Wave Life Sciences, Inc. (WVE)
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Wave Life Sciences, Inc. (WVE) reported revenue of $13 million for Q3 FY2026, the quarter ended 30 September 2026, up 72.9% on the same quarter a year earlier. Net income was -$62 million, and diluted earnings per share $-0.30. The figures are the company's own, from the 10-Q it filed with the SEC on 27 October 2026.
Revenue$13 millionup 72.9%
Net income-$62 million
Diluted EPS$-0.30
QuarterQ3 FY2026ended 30 September 2026
Wave Life Sciences (WVE) in brief
Wave Life Sciences (WVE) reported revenue of $43 million for fiscal 2025, the year ended 31 December 2025, down 60.5% on the year before.
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Net loss was $204 million and the diluted loss per share $1.21. Revenue was $108 million in fiscal 2024, $113 million in fiscal 2023, $4 million in fiscal 2022 and $41 million in fiscal 2021. Net income in the same years was a loss of $97 million, a loss of $58 million, a loss of $162 million and a loss of $122 million. Over the twelve months to 30 September 2026, Wave Life Sciences reported revenue of $71 million and net loss of $211 million. Revenue grew 16.3% a year, compounded, over the five years to fiscal 2025. Wave Life Sciences had 197 million shares outstanding at the latest filed count. At 30 September 2026 it carried $0 million of debt and $197 million of cash. At the close of 29 October 2026 the market cap of Wave Life Sciences was $715 million.Ratios
From the filings
ROE-52.4%
ROCE-56.6%
Operating margin-320.9%
Net margin-296.9%
FCF marginn/a
Interest covern/a
Debt to equity0.00
Cash conversionn/a
Share count, last 12 months23.0%
Sales CAGR, 3 years127.1%
Profit CAGR, 3 yearsn/a
EPS, TTM-$1.07
At the close of 29 October 2026
Price$3.62
Market cap$715 million
Stock P/En/a
Price to book1.78
EV / EBITDAn/a
Dividend yieldn/a
Market cap / sales10.08
52-week high$21.31
52-week low$3.07
Price, 1 year-56.1%
Price CAGR, 3 years-12.6%
Price CAGR, 5 years-4.6%
Worked from the filed figures; hover a name for the formula.
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The priced ones use the latest price, the last regular-hours trade on IEX. Wave Life Sciences, Inc.'s balance sheet shows no borrowings, so debt here is nil; lease liabilities are a separate line. Nothing here is a valuation or a view.WVEgreeksoup.ai
Daily prices to 29 October 2026, adjusted for splits; from 28 September 2026 each day's price is the last regular-hours trade on IEX.
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Data provided for free by IEX. By accessing or using IEX Historical Data, you agree to the IEX Historical Data Terms of Use. Day by day for the last three years; before that one point a week, carrying the week's last close and its average daily volume, so a volume bar means the same thing across the whole series; the bars sit under the price on their own scale, on the right. The moving averages need consecutive days and are drawn from the daily part. P/E is the close over the trailing four quarters' EPS as filed at each filing date, on the current share count; the dashed line is the median over the range shown. Sales and margin are quarterly revenue and the operating margin from the tables above. EV/EBITDA, price to book and market cap to sales use the latest filed balance sheet and share count at each date. Before the quarters on file begin, P/E, price to book and market cap to sales stand on each annual report from the day it was filed. Drawn in your browser; the range and overlay you pick are remembered here only.The public record on WVE
| Dividends | no dividend in its filings for fiscal 2013 onward |
| Filings | 30 in twelve months: 16 current reports (8-K), about 10 regulation FD disclosure; 8 other events; 6 results of operations; 2 material agreement; 1 shareholder vote |
| Planned insider sales | 15 Form 144 notices in twelve months, $11.5 million; latest 12 August 2026 |
| Options tape | put/call 0.1 by open interest at the 29 October 2026 close; the straddle prices a 257.5% move to 20 November 2026 |
| 13F holders | 239 funds reported a position for the quarter to 30 June 2026; largest Ra Capital Management, L.P. |
| Insider trading | 47 sales and 6 purchases on Form 4 in twelve months |
| Congress | 0 House trades disclosed in six months |
| Short interest | 21.2 million shares short, 6.53 days to cover at 15 October 2026 |
| Documents | the 10-K, the 10-Qs, the proxy and 6 earnings press releases, each linked |
Quarterly results, the last 20 quarters
| Q4 FY2020 * | Q2 FY2021 | Q3 FY2021 | Q1 FY2022 | Q2 FY2022 | Q3 FY2022 | Q4 FY2022 * | Q1 FY2023 | Q2 FY2023 | Q3 FY2023 | Q4 FY2023 * | Q1 FY2024 | Q2 FY2024 | Q1 FY2025 | Q2 FY2025 | Q3 FY2025 | Q4 FY2025 * | Q1 FY2026 | Q2 FY2026 | Q3 FY2026 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | 9.4 | 2.8 | 36.4 | 1.8 | 0.4 | 0.3 | 1.2 | 12.9 | 22.1 | 49.2 | 29.1 | 12.5 | 19.7 | 9.2 | 8.7 | 7.6 | 17.2 | 38.2 | 2.3 | 13.2 |
| R&D | 30.0 | 31.6 | 31.1 | 27.5 | 29.7 | 27.6 | 31.1 | 31.0 | 33.3 | 31.6 | 34.1 | 33.4 | 40.4 | 40.6 | 43.5 | 45.9 | 52.8 | 47.4 | 51.3 | 53.8 |
| Operating income | -30.3 | -39.8 | -7.6 | -38.1 | -42.2 | -38.9 | -43.6 | -30.3 | -23.5 | 4.4 | -18.7 | -34.5 | -35.0 | -49.8 | -52.8 | -56.4 | -56.5 | -31.3 | -73.8 | -66.0 |
| Operating margin | -321% | -1435% | -21% | -2177% | -11244% | -13649% | -3516% | -234% | -106% | 9% | -64% | -275% | -178% | -543% | -606% | -741% | -327% | -82% | -3248% | -502% |
| Pre-tax income | -29.6 | -38.8 | -6.2 | -37.8 | -41.3 | -39.0 | -43.0 | -27.4 | -21.1 | 6.6 | -16.3 | -31.6 | -32.9 | -46.9 | -50.5 | -53.9 | -53.2 | -26.1 | -69.4 | -61.9 |
| Tax rate | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | -10% | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| Net income | -28.8 | -38.8 | -6.2 | -37.8 | -41.3 | -39.0 | -43.7 | -27.4 | -21.1 | 7.3 | -16.3 | -31.6 | -32.9 | -46.9 | -50.5 | -53.9 | -53.2 | -26.1 | -69.4 | -61.9 |
| Net margin | -305% | -1396% | -17% | -2161% | -11012% | -13686% | -3528% | -212% | -95% | 15% | -56% | -252% | -167% | -511% | -580% | -708% | -308% | -68% | -3053% | -471% |
| Diluted EPS | -$0.59 | -$0.78 | -$0.12 | -$0.62 | -$0.62 | -$0.42 | -$0.47 | -$0.27 | -$0.20 | $0.07 | -$0.15 | -$0.24 | -$0.25 | -$0.29 | -$0.31 | -$0.32 | -$0.30 | -$0.13 | -$0.34 | -$0.30 |
| Operating cash flow | -31.4 | -9.4 | -28.2 | -39.9 | -28.8 | -25.6 | -33.4 | 85.5 | -37.3 | -34.5 | -33.2 | -33.4 | -27.5 | -63.0 | -46.0 | -44.7 | -33.8 | -59.6 | -53.6 | -60.1 |
| Capital expenditure | 0.6 | 0.3 | 0.1 | 0.2 | 0.5 | 0.5 | 0.2 | 0.5 | 0.1 | 0.2 | 0.4 | 0.4 | 0.1 | 0.2 | 0.3 | 0.2 | n/a | 0.4 | 0.9 | 0.0 |
| Free cash flow | -32.0 | -9.7 | -28.3 | -40.1 | -29.3 | -26.1 | -33.6 | 85.0 | -37.3 | -34.7 | -33.6 | -33.8 | -27.5 | -63.2 | -46.3 | -44.9 | n/a | -60.0 | -54.5 | -60.2 |
| Shares outstanding | 49m | 51m | 52m | 61m | 87m | 87m | 87m | 98m | 99m | 99m | 119m | 122m | 122m | 154m | 156m | 160m | 188m | 192m | 193m | 197m |
| Filing | 10-K | 10-Q | 10-Q | 10-Q | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q |
Each quarter as filed, linked to its filing.
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* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS, and its diluted share count where shown, are from the company's results press release for that quarter, checked against the company's filed figures or a second data source. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.Income statement (profit and loss), 11 fiscal years and the trailing twelve months
Play it forward: change any box and its column follows; every box opens at the company's own record, shown under the row's name, and says when you set it outside every year in the table.
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Each column runs from the last twelve months as filed to the year chosen in its heading, at a yearly rate. Sales growth starts at the company's own five-year rate and eases a third of the way each year toward the median of the 129 peers in Pharmaceutical Products (15.3% a year), because a rate far from the rest rarely lasts. Before you open a year, the strip reads today's price backwards: the yearly sales growth that brings EPS, at the company's own margins, tax and share count, to today's price at the median P/E of the 65 peers in Pharmaceutical Products (22.5). Low, middle, high opens three columns for one year: the low and high cases take the company's own weaker and stronger years in the table (the lower and upper quarter of its yearly sales growth and operating margin) and the lower and higher of today's P/E and its peers'; the middle is the boxes as they open. Net income keeps the share that went to minority holders; EPS is net income over the diluted shares, on the same basis as the EPS in the table. The price is that year's EPS at the P/E you set, and the yearly return runs from today's price to the year's end. These are your assumptions and your arithmetic, not an estimate of ours. The link carries your columns, so you can send the forecast to someone.| FY2015 | FY2016 † | FY2017 † | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | 0.2 | 1.1 | 3.9 | 14.4 | 16.0 | 20.1 | 41.0 | 3.6 | 113 | 108 | 42.7 | 70.9 |
| Research and development | 9.1 | 40.8 | 79.3 | 134 | 175 | 131 | 122 | 116 | 130 | 160 | 183 | 205 |
| Operating income | -19.3 | -55.7 | -103 | -160 | -208 | -153 | -127 | -163 | -68.0 | -110 | -215 | -228 |
| Operating margin | -12696.1% | -5102.6% | -2635.0% | -1106.7% | -1303.4% | -763.9% | -310.1% | -4459.3% | -60.0% | -101.9% | -504.1% | -320.9% |
| Pre-tax income | -19.2 | -55.2 | -101 | -147 | -194 | -151 | -122 | -161 | -58.2 | -97.0 | -204 | -211 |
| Income tax | 0.0 | 0.5 | 0.8 | 0.1 | 0.0 | -0.8 | -0.2 | 0.7 | -0.7 | 0.0 | 0.0 | 0.0 |
| Net income | -19.2 | -55.7 | -102 | -147 | -194 | -150 | -122 | -162 | -57.5 | -97.0 | -204 | -211 |
| Net margin | -12631.6% | -5097.1% | -2621.0% | -1017.4% | -1211.5% | -746.7% | -298.4% | -4434.7% | -50.8% | -89.6% | -478.3% | -296.9% |
| Diluted EPS | -$1.83 | -$2.43 | -$3.85 | -$5.06 | -$5.72 | -$3.82 | -$2.36 | -$2.05 | -$0.54 | -$0.70 | -$1.21 | -$1.07 |
| Filing | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
From each year's 10-K, linked; TTM is the last four quarters.
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Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are. † The year as the company last restated it in a later filing; rest on a figure for the one first filed. EPS is as filed.Cash flow and capital returned
Follow the cash: free cash flow, which is operating cash flow less capital expenditure and share-based pay, for five years and after, in today's money.
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The figure a share at the top is what a discounted cash flow calls intrinsic value, worked out on your assumptions. Everything after year five is one sum: the sixth year's cash, growing at the long-run rate every year after, added up and brought back to today's money. Each year runs from the last twelve months as filed. Sales growth opens where Play it forward does: the company's own five-year rate, easing a third of the way each year toward the median of the 129 peers in Pharmaceutical Products (15.3% a year); change a year and the years after it follow. Operating cash flow, capital expenditure and share-based pay open at the company's own median share of sales over its last five years, shown under each row. Share-based pay is taken off because operating cash flow adds back the shares paid to staff as if they cost nothing; set it to 0 to leave it in. Capital spending counts every capital line the company files in its cash flow, such as equipment it leases to customers, software, wells or property it develops, named under the row, while the Capital expenditure row in the table below stays the one line as filed; buying a business, securities or a finished property is not counted. The discount rate opens at 10%, about what US stocks have returned a year over the long run, so it is the return you give up by holding this company instead of the market; the growth after year five opens at 3%, a little under the US economy's long-run growth in dollars, because no company outgrows it for ever. Net debt is the debt and short-term borrowings less the cash on the latest balance sheet that shows the debt; the figure per share divides what is left by the diluted share count. These are your assumptions and your arithmetic, not an estimate of ours. The link carries them, so you can send them to someone.| FY2015 | FY2016 † | FY2017 † | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | -12.5 | -31.9 | -83.7 | -22.9 | -188 | -116 | -89.0 | -128 | -19.4 | -151 | -187 | -207 |
| Capital expenditure | 1.9 | 5.6 | 18.9 | 9.9 | 3.9 | 1.3 | 0.6 | 1.4 | 1.1 | 0.9 | 0.7 | n/a |
| Free cash flow | -14.4 | -37.5 | -103 | -32.8 | -192 | -117 | -89.6 | -129 | -20.5 | -152 | -188 | n/a |
| Free cash flow margin | -9463.2% | -3433.3% | -2634.4% | -227.6% | -1202.2% | -584.4% | -218.6% | -3539.1% | -18.1% | -140.3% | -440.5% | n/a |
| Cash from investing | n/a | -5.6 | -18.9 | -9.9 | -3.9 | -1.3 | -0.6 | -1.3 | -1.1 | -0.9 | -0.7 | -235 |
| Cash from financing | n/a | 29.1 | 94.4 | 65.1 | 164 | 155 | 55.8 | 67.2 | 133 | 254 | 488 | 443 |
| Depreciation and amortisation | 0.6 | 0.8 | 2.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
| Share-based compensation | 4.0 | 6.8 | 12.1 | 15.6 | 19.5 | 14.3 | 16.4 | 17.2 | 9.8 | 13.1 | 25.0 | 37.4 |
| Diluted shares, weighted | n/a | n/a | n/a | n/a | n/a | n/a | 52m | 79m | 106m | 138m | 169m | 204m |
| Shares outstanding at period end | 22m | 24m | 28m | 29m | 34m | 49m | 60m | 87m | 119m | 153m | 188m | 197m |
| Filing | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K |
Cash paid in the year, from the cash flow statement.
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The dividend per share is as declared. Diluted shares are the weighted average for the year; a falling count is the buybacks net of issuance. TTM sums the last four quarters; the share counts are the latest quarter's.Balance sheet at year end
| FY2015 | FY2016 † | FY2017 † | FY2018 | FY2019 | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 | TTM | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Funded by | ||||||||||||
| Shareholders' equity | 153 | 135 | 140 | 73.3 | 63.7 | 82.8 | 32.5 | -45.1 | 39.6 | 210 | 518 | 402 |
| Redeemable equity | n/a | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 7.9 | 0.0 |
| Debt | n/a | n/a | n/a | n/a | n/a | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| Operating lease liabilities | n/a | n/a | n/a | n/a | 29.3 | 25.6 | 25.0 | 32.1 | 25.4 | 17.8 | 9.4 | 38.9 |
| Other liabilities | 11.9 | 22.1 | 34.2 | 215 | 183 | 163 | 142 | 151 | 202 | 117 | 103 | 67.1 |
| Total liabilities and equity | 165 | 165 | 182 | 296 | 284 | 279 | 207 | 146 | 275 | 352 | 638 | 508 |
| Owned | ||||||||||||
| Fixed assets | 2.8 | 8.6 | 27.3 | 39.9 | 36.4 | 29.2 | 22.3 | 17.3 | 13.1 | 10.1 | 7.4 | 6.2 |
| Investments | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | 0.0 | 234 |
| Cash and equivalents | 161 | 150 | 143 | 175 | 147 | 184 | 151 | 88.5 | 200 | 302 | 602 | 197 |
| Receivables | n/a | n/a | 1.0 | 10.0 | 20.0 | 30.0 | n/a | n/a | 21.1 | 1.4 | 1.3 | 12.0 |
| Other assets | 1.4 | 5.9 | 11.0 | 71.2 | 80.7 | 35.5 | 34.2 | 40.6 | 40.4 | 38.6 | 27.8 | 58.7 |
| Total assets | 165 | 165 | 182 | 296 | 284 | 279 | 207 | 146 | 275 | 352 | 638 | 508 |
| Filing | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | 10-K | |
At the fiscal year end; the TTM column is the latest quarter end.
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Both totals are the company's own. Other liabilities is the filed total less the rows above it: payables, deferred revenue, taxes, borrowings the rows above do not carry and the rest; other assets is the same on the other side. Investments add the current and non-current lines as filed. Debt is the company's own stated total where it files one, otherwise its long-term debt with the current maturities, never parts added together. A row is left blank in a year where the lines shown overlap and the remainder would fall below nil.Compounded growth
| 10 years | 5 years | 3 years | TTM | |
|---|---|---|---|---|
| Sales growth, compounded | 75.7% | 16.3% | 127.1% | 57.0% |
| Profit growth, compounded | n/a | n/a | n/a | n/a |
| Return on equity, average | -156.2% | -151.8% | -77.0% | -39.4% |
Yearly growth, compounded; TTM is the last four quarters against the four before.
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Return on equity is net income over shareholders' equity at each year end, averaged over the window (the TTM column is the latest year alone); equity is the parent's shareholders' equity as tagged in the 10-K. Arithmetic on filed numbers, nothing forecast.Questions
What was Wave Life Sciences' revenue in fiscal 2025?
Wave Life Sciences (WVE) reported revenue of $43 million for fiscal 2025, the year ended 31 December 2025, down 60.5% on the year before.
How much did Wave Life Sciences earn in fiscal 2025?
Net loss was $204 million for fiscal 2025, and the diluted loss per share $1.21.
What is Wave Life Sciences' market cap?
The market cap of Wave Life Sciences was $715 million at the close of 29 October 2026.
How much debt does Wave Life Sciences have?
At 30 September 2026 Wave Life Sciences carried $0 million of debt and $197 million of cash.
Peers: Pharmaceutical Products
| Company | Market cap | P/E | ROE | Op. margin | Sales growth TTM | Debt to equity | Div. yield |
|---|---|---|---|---|---|---|---|
| Eli Lilly & Co. LLY | $1.29 trillion | 44.56 | 68.5% | n/a | 45.5% | 1.23 | 0.5% |
| Johnson & Johnson JNJ | $662.4 billion | 41.69 | 19.7% | n/a | 7.8% | 0.55 | 1.9% |
| AbbVie Inc. ABBV | $513.9 billion | 82.15 | n/a | 26.2% | 10.4% | n/a | 2.3% |
| Merck & Co., Inc. MRK | $361.0 billion | 117.05 | 7.6% | n/a | 4.6% | 1.29 | 2.3% |
| Novartis AG NVS * | $307.3 billion | 22.52 | 30.3% | n/a | 8.4% | 0.62 | 2.5% |
| AstraZeneca PLC AZN * | $270.6 billion | 26.68 | 21.0% | 23.4% | 8.6% | 0.57 | 1.8% |
| Abbott Laboratories ABT | $180.9 billion | 33.84 | 10.6% | 15.8% | 8.1% | 0.64 | 2.4% |
| Novo Nordisk A/S NVO * | $174.8 billion | 11.34 | 52.8% | 41.3% | 6.4% | 0.67 | 4.5% |
| Pfizer Inc. PFE | $170.7 billion | 39.41 | 5.1% | n/a | -0.2% | 0.74 | 5.7% |
| Vertex Pharmaceuticals Inc. VRTX | $136.8 billion | 31.44 | 21.8% | 38.0% | 10.2% | 0.00 | n/a |
| Bristol-Myers Squibb Co. BMY | $125.5 billion | 13.61 | 39.5% | 22.6% | 4.2% | 1.83 | 4.1% |
| Sanofi SNY * | $105.2 billion | 12.09 | 10.9% | n/a | 6.2% | 0.26 | 5.1% |
All 167 in Pharmaceutical Products
| Company | Market cap | P/E | ROE | Op. margin | Sales growth TTM | Debt to equity | Div. yield |
|---|---|---|---|---|---|---|---|
| Eli Lilly & Co. LLY | $1.29 trillion | 44.56 | 68.5% | n/a | 45.5% | 1.23 | 0.5% |
| Johnson & Johnson JNJ | $662.4 billion | 41.69 | 19.7% | n/a | 7.8% | 0.55 | 1.9% |
| AbbVie Inc. ABBV | $513.9 billion | 82.15 | n/a | 26.2% | 10.4% | n/a | 2.3% |
| Merck & Co., Inc. MRK | $361.0 billion | 117.05 | 7.6% | n/a | 4.6% | 1.29 | 2.3% |
| Novartis AG NVS * | $307.3 billion | 22.52 | 30.3% | n/a | 8.4% | 0.62 | 2.5% |
| AstraZeneca PLC AZN * | $270.6 billion | 26.68 | 21.0% | 23.4% | 8.6% | 0.57 | 1.8% |
| Amgen Inc. AMGN | $249.1 billion | 28.64 | 74.8% | 30.0% | 9.1% | 4.90 | 2.1% |
| Gilead Sciences, Inc. GILD | $205.5 billion | n/a | -27.4% | -8.2% | 5.5% | 2.22 | 1.9% |
| Abbott Laboratories ABT | $180.9 billion | 33.84 | 10.6% | 15.8% | 8.1% | 0.64 | 2.4% |
| Novo Nordisk A/S NVO * | $174.8 billion | 11.34 | 52.8% | 41.3% | 6.4% | 0.67 | 4.5% |
| Pfizer Inc. PFE | $170.7 billion | 39.41 | 5.1% | n/a | -0.2% | 0.74 | 5.7% |
| Vertex Pharmaceuticals Inc. VRTX | $136.8 billion | 31.44 | 21.8% | 38.0% | 10.2% | 0.00 | n/a |
| Bristol-Myers Squibb Co. BMY | $125.5 billion | 13.61 | 39.5% | 22.6% | 4.2% | 1.83 | 4.1% |
| Sanofi SNY * | $105.2 billion | 12.09 | 10.9% | n/a | 6.2% | 0.26 | 5.1% |
| GSK plc GSK * | $97.7 billion | 13.11 | 34.9% | 24.3% | 4.1% | 1.08 | 3.5% |
| Moderna, Inc. MRNA | $88.9 billion | n/a | -46.6% | -149.0% | -27.6% | 0.09 | n/a |
| Regeneron Pharmaceuticals, Inc. REGN | $86.6 billion | 20.20 | 13.7% | 24.7% | 9.3% | 0.06 | 0.4% |
| Takeda Pharmaceutical Company Limited TAK * | $63.3 billion | n/a | -2.1% | 0.1% | -1.7% | 0.66 | 3.3% |
| argenx SE ARGX * | $55.5 billion | 45.86 | 17.6% | n/a | 89.9% | 0.00 | n/a |
| Teva Pharmaceutical Industries Ltd. TEVA | $48.3 billion | 69.13 | 9.1% | 9.3% | 4.1% | 2.14 | n/a |
| IDEXX Laboratories Inc. IDXX | $45.4 billion | 40.50 | 70.7% | 32.0% | 12.8% | 0.60 | n/a |
| Biogen Inc. BIIB | $36.9 billion | 106.76 | 1.8% | 4.3% | 2.3% | 0.41 | n/a |
| Royalty Pharma plc RPRX | $36.7 billion | 35.27 | 8.3% | 59.6% | 10.0% | 0.92 | 1.4% |
| Genmab A/S GMAB * | $36.3 billion | 36.74 | 16.5% | 28.6% | 19.2% | 0.90 | n/a |
| Zoetis Inc. ZTS | $32.6 billion | 12.98 | 83.1% | n/a | 1.5% | 2.87 | 2.6% |
| Roivant Sciences Ltd. ROIV | $27.1 billion | n/a | -6.3% | -7,914.8% | -67.6% | 0.00 | n/a |
| United Therapeutics Corp. UTHR | $25.3 billion | 21.23 | 20.5% | 44.4% | 2.5% | 0.00 | n/a |
| Insmed Inc. INSM | $24.5 billion | n/a | -83.4% | -37.1% | 240.0% | 0.76 | n/a |
| Alnylam Pharmaceuticals, Inc. ALNY | $23.3 billion | 9.03 | 75.6% | 19.5% | 56.2% | 0.28 | n/a |
| BioNTech SE BNTX * | $22.4 billion | n/a | -5.9% | -49.0% | 4.3% | 0.01 | n/a |
| Viatris Inc. VTRS | $22.1 billion | n/a | -2.9% | -0.6% | 4.4% | 0.94 | 2.5% |
| Exelixis, Inc. EXEL | $16.2 billion | 19.84 | 48.3% | 40.2% | 9.1% | 0.00 | n/a |
| Halozyme Therapeutics, Inc. HALO | $15.0 billion | 39.14 | 288.1% | 35.9% | 41.2% | 14.95 | n/a |
| Neurocrine Biosciences Inc. NBIX | $14.9 billion | 21.47 | 19.1% | 23.6% | 34.4% | 0.00 | n/a |
| BridgeBio Pharma, Inc. BBIO | $13.9 billion | n/a | n/a | -38.5% | 167.3% | n/a | n/a |
| Jazz Pharmaceuticals plc JAZZ | $13.5 billion | 14.33 | 19.6% | 19.5% | 12.6% | 0.91 | n/a |
| Dr. Reddy’s Laboratories Limited RDY * | $11.8 billion | 26.05 | 11.4% | 15.0% | 3.2% | 0.21 | 0.6% |
| Elanco Animal Health Inc. ELAN | $11.6 billion | n/a | -3.0% | n/a | 12.0% | 0.56 | n/a |
| Bio-Techne Corp. TECH | $11.3 billion | 63.23 | 8.6% | 20.7% | -0.4% | 0.09 | 0.4% |
| Biomarin Pharmaceutical Inc. BMRN | $11.1 billion | 155.19 | 1.2% | 4.4% | 11.2% | 0.66 | n/a |
| Twist Bioscience Corp. TWST | $10.9 billion | n/a | -30.7% | -33.6% | 19.2% | 0.03 | n/a |
| Repligen Corp. RGEN | $10.6 billion | 258.47 | 2.0% | 8.2% | 16.5% | 0.26 | n/a |
| Kymera Therapeutics, Inc. KYMR | $10.5 billion | n/a | -21.6% | -396.0% | 133.8% | 0.00 | n/a |
| Madrigal Pharmaceuticals, Inc. MDGL | $10.0 billion | n/a | -62.1% | -25.1% | 149.0% | 0.65 | n/a |
| Krystal Biotech, Inc. KRYS | $9.6 billion | 40.64 | 17.8% | 44.9% | 22.6% | 0.00 | n/a |
| Protagonist Therapeutics, Inc. PTGX | $9.3 billion | 140.03 | 9.9% | 20.7% | 34.8% | 0.00 | n/a |
| Corcept Therapeutics Inc. CORT | $9.3 billion | 204.67 | 7.8% | 0.8% | 16.0% | 0.00 | n/a |
| ImmunityBio, Inc. IBRX | $9.2 billion | n/a | n/a | -151.9% | 192.9% | n/a | n/a |
| TG Therapeutics, Inc. TGTX | $8.9 billion | 21.20 | 73.1% | 17.1% | 76.1% | 1.23 | n/a |
| Cytokinetics Inc. CYTK | $8.8 billion | n/a | n/a | -1,046.1% | -21.1% | n/a | n/a |
| Arrowhead Pharmaceuticals, Inc. ARWR | $8.5 billion | n/a | -68.7% | -33.8% | 16.8% | 1.86 | n/a |
| Kiniksa Pharmaceuticals International, plc KNSA | $8.3 billion | 75.10 | 15.4% | 13.8% | 58.2% | 0.00 | n/a |
| Alkermes plc. ALKS | $7.6 billion | 119.42 | 3.7% | 7.0% | 10.8% | 0.84 | n/a |
| Axsome Therapeutics, Inc. AXSM | $7.5 billion | n/a | -230.1% | -24.0% | 56.9% | 2.26 | n/a |
| Ionis Pharmaceuticals Inc. IONS | $7.4 billion | n/a | -128.5% | -68.0% | -7.4% | 3.01 | n/a |
| Amneal Pharmaceuticals, Inc. AMRX | $6.8 billion | 43.55 | 476.5% | 14.6% | 9.3% | 80.86 | n/a |
| Lantheus Holdings, Inc. LNTH | $6.5 billion | 24.23 | 21.0% | 19.4% | 2.3% | 0.43 | n/a |
| Rhythm Pharmaceuticals, Inc. RYTM | $6.4 billion | n/a | -199.4% | -83.6% | 53.5% | 1.03 | n/a |
| Ligand Pharmaceuticals Inc. LGND | $6.3 billion | 33.94 | 20.4% | 32.6% | 54.9% | 1.16 | n/a |
| CG Oncology, Inc. CGON | $5.6 billion | n/a | -21.8% | -4,056.2% | 1,030.3% | 0.00 | n/a |
| Mirum Pharmaceuticals, Inc. MIRM | $5.6 billion | n/a | n/a | -134.9% | 44.0% | n/a | n/a |
| PTC Therapeutics, Inc. PTCT | $5.4 billion | n/a | n/a | 12.8% | -35.1% | n/a | n/a |
| Scholar Rock Holding Corp. SRRK | $5.4 billion | n/a | n/a | n/a | n/a | 0.77 | n/a |
| Crispr Therapeutics AG CRSP | $5.2 billion | n/a | -25.8% | -3,990.0% | -64.8% | 0.34 | n/a |
| Gossamer Bio, Inc. GOSS | $5.2 billion | n/a | n/a | -311.7% | 32.4% | n/a | n/a |
| Travere Therapeutics, Inc. TVTX | $4.8 billion | n/a | -177.2% | -6.8% | 77.1% | 24.58 | n/a |
| Adaptive Biotechnologies Corp. ADPT | $4.5 billion | n/a | -44.7% | -12.2% | 50.1% | 2.34 | n/a |
| Iovance Biotherapeutics, Inc. IOVA | $4.3 billion | n/a | -39.3% | -92.7% | 34.5% | 0.00 | n/a |
| Relay Therapeutics, Inc. RLAY | $4.3 billion | n/a | -32.1% | -2,999.7% | 23.9% | 0.00 | n/a |
| Indivior Pharmaceuticals, Inc. INDV | $4.2 billion | n/a | n/a | 40.6% | 16.4% | n/a | n/a |
| Arcutis Biotherapeutics, Inc. ARQT | $4.0 billion | 152.29 | 12.9% | 7.4% | 76.1% | 0.49 | n/a |
| Liquidia Corp. LQDA | $4.0 billion | 32.87 | 71.0% | 37.4% | 2,233.6% | n/a | n/a |
| AbCellera Biologics Inc. ABCL | $4.0 billion | n/a | -18.4% | -340.2% | 101.3% | 0.00 | n/a |
| Tango Therapeutics, Inc. TNGX | $3.8 billion | n/a | -12.1% | -253.4% | 121.5% | 0.00 | n/a |
| Organon & Co. OGN | $3.6 billion | 17.96 | 20.8% | n/a | -2.5% | 8.50 | 0.6% |
| Xenon Pharmaceuticals Inc. XENE | $3.6 billion | n/a | -32.9% | n/a | n/a | 0.00 | n/a |
| Acadia Pharmaceuticals Inc. ACAD | $3.6 billion | 9.35 | 29.1% | 7.6% | 11.8% | 0.00 | n/a |
| Viking Therapeutics, Inc. VKTX | $3.4 billion | n/a | -106.6% | n/a | n/a | 0.43 | n/a |
| Bausch Health Companies Inc. BHC | $3.3 billion | n/a | n/a | 11.2% | 10.8% | n/a | n/a |
| DBV Technologies S.A. DBVT | $3.2 billion | n/a | -139.5% | -5,420.1% | -31.5% | 0.00 | n/a |
| Tarsus Pharmaceuticals, Inc. TARS | $3.2 billion | n/a | -13.4% | -8.0% | 105.2% | 0.21 | 0.0% |
| Ideaya Biosciences, Inc. IDYA | $3.2 billion | n/a | n/a | n/a | n/a | 0.00 | n/a |
| Denali Therapeutics Inc. DNLI | $3.1 billion | n/a | n/a | n/a | n/a | 0.00 | n/a |
| Beam Therapeutics Inc. BEAM | $3.0 billion | n/a | -8.0% | -242.3% | 158.9% | 0.09 | n/a |
| Nurix Therapeutics, Inc. NRIX | $3.0 billion | 11.73 | 30.5% | 41.3% | 738.8% | 0.00 | 0.0% |
| Viridian Therapeutics, Inc. VRDN | $2.8 billion | n/a | -58.4% | -569.7% | 23,220.3% | 0.54 | n/a |
| Silence Therapeutics plc SLN | $2.8 billion | n/a | -155.8% | -11,106.8% | -97.7% | 0.00 | n/a |
| Neogen Corp. NEOG | $2.7 billion | n/a | -2.7% | -0.8% | -0.3% | 0.37 | n/a |
| Adma Biologics, Inc. ADMA | $2.6 billion | 16.79 | 41.4% | 43.8% | 8.0% | 0.48 | n/a |
| NewAmsterdam Pharma Co. N.V. NAMS | $2.4 billion | n/a | -41.1% | -3,432.2% | -88.9% | 0.00 | n/a |
| Supernus Pharmaceuticals, Inc. SUPN | $2.4 billion | n/a | -4.1% | -5.7% | 26.9% | 0.00 | n/a |
| Precigen, Inc. PGEN | $2.4 billion | n/a | n/a | n/a | n/a | 2.15 | n/a |
| Arcus Biosciences, Inc. RCUS | $2.4 billion | n/a | -99.1% | -415.4% | -55.3% | 0.22 | n/a |
| Celldex Therapeutics, Inc. CLDX | $2.3 billion | n/a | -42.1% | -207,534.4% | -97.3% | 0.00 | n/a |
| Prestige Consumer Healthcare Inc. PBH | $2.3 billion | 13.66 | 9.0% | 26.3% | -1.4% | 1.05 | n/a |
| Aurinia Pharmaceuticals Inc. AUPH | $2.3 billion | 7.51 | 51.1% | 48.4% | 19.8% | 0.00 | n/a |
| Recursion Pharmaceuticals, Inc. RXRX | $2.3 billion | n/a | -56.7% | -991.7% | -15.1% | 0.02 | n/a |
| Harmony Biosciences Holdings, Inc. HRMY | $2.2 billion | 12.53 | 18.1% | 24.0% | 24.3% | 0.15 | n/a |
| Agios Pharmaceuticals, Inc. AGIO | $2.2 billion | n/a | -40.1% | -466.8% | 140.6% | 0.00 | n/a |
| Perrigo Co. plc PRGO | $2.2 billion | n/a | -69.0% | -37.7% | -4.2% | 1.31 | 7.3% |
| Vericel Corp. VCEL | $2.2 billion | 91.34 | 6.5% | 6.0% | 23.0% | 0.00 | n/a |
| Biocryst Pharmaceuticals Inc. BCRX | $2.2 billion | n/a | n/a | -33.3% | 68.7% | n/a | n/a |
| Xencor Inc. XNCR | $2.2 billion | n/a | -32.5% | -205.8% | -28.6% | 0.21 | n/a |
| Immunome Inc. IMNM | $2.1 billion | n/a | -48.4% | n/a | n/a | 0.00 | n/a |
| Septerna, Inc. SEPN | $2.1 billion | n/a | -6.3% | -44.0% | 13,520.1% | 0.00 | n/a |
| Zymeworks Inc. ZYME | $2.1 billion | n/a | -186.6% | -419.0% | -69.8% | 0.00 | n/a |
| Trulieve Cannabis Corp. TRLV | $2.0 billion | n/a | -61.8% | -24.3% | -3.9% | 0.38 | n/a |
| Sarepta Therapeutics, Inc. SRPT | $2.0 billion | n/a | -8.9% | -7.3% | -20.4% | 0.55 | n/a |
| Vir Biotechnology, Inc. VIR | $2.0 billion | n/a | -25.6% | -92.4% | 1,495.9% | 0.00 | n/a |
| Schrodinger, Inc. SDGR | $1.9 billion | n/a | -16.5% | -59.2% | 8.9% | 0.00 | n/a |
| Xeris Biopharma Holdings, Inc. XERS | $1.9 billion | n/a | n/a | 10.9% | 36.3% | n/a | n/a |
| Intellia Therapeutics, Inc. NTLA | $1.9 billion | n/a | -55.0% | -711.7% | 12.6% | 0.00 | n/a |
| Zenas BioPharma, Inc. ZBIO | $1.8 billion | n/a | n/a | n/a | n/a | 1.20 | n/a |
| Maze Therapeutics, Inc. MAZE | $1.8 billion | n/a | n/a | n/a | n/a | 0.09 | n/a |
| uniQure N.V. QURE | $1.8 billion | n/a | -77.8% | -1,071.5% | 30.2% | 0.15 | n/a |
| Novavax Inc. NVAX | $1.7 billion | n/a | n/a | -56.6% | -61.6% | n/a | n/a |
| Nuvation Bio Inc. NUVB | $1.7 billion | n/a | -59.0% | -81.0% | 1,083.6% | 0.98 | n/a |
| Ultragenyx Pharmaceutical Inc. RARE | $1.7 billion | n/a | n/a | -73.6% | 17.5% | n/a | n/a |
| ANI Pharmaceuticals Inc. ANIP | $1.6 billion | 15.57 | 18.1% | 15.4% | 30.9% | 1.02 | n/a |
| Stoke Therapeutics, Inc. STOK | $1.6 billion | n/a | -60.2% | -809.7% | -86.2% | 0.00 | n/a |
| UroGen Pharma Ltd. URGN | $1.6 billion | n/a | n/a | -35.3% | 100.3% | n/a | n/a |
| Immunocore Holdings plc IMCR | $1.6 billion | n/a | -4.3% | -5.2% | 21.0% | 0.94 | 0.0% |
| Ocular Therapeutix, Inc. OCUL | $1.6 billion | n/a | -58.0% | -603.0% | -8.1% | 0.14 | n/a |
| Phibro Animal Health Corp. PAHC | $1.6 billion | 16.00 | 25.9% | 12.8% | 17.1% | 1.91 | 1.2% |
| Innoviva, Inc. INVA | $1.5 billion | 5.20 | 29.0% | 36.9% | 18.8% | 0.21 | n/a |
| Eton Pharmaceuticals, Inc. ETON | $1.5 billion | 137.69 | 27.2% | 15.4% | 81.5% | 0.60 | n/a |
| Pacira BioSciences, Inc. PCRX | $1.4 billion | 103.97 | 2.2% | 2.7% | 5.7% | 0.54 | n/a |
| Taysha Gene Therapies, Inc. TSHA | $1.4 billion | n/a | -38.6% | -2,792.3% | -32.3% | 0.13 | n/a |
| Omeros Corp. OMER | $1.4 billion | n/a | n/a | n/a | n/a | n/a | n/a |
| Syndax Pharmaceuticals Inc. SNDX | $1.3 billion | n/a | -1,462.1% | -77.1% | 222.3% | 16.17 | n/a |
| Cronos Group Inc. CRON | $1.2 billion | 16.82 | 6.5% | -1.4% | 37.5% | 0.00 | n/a |
| Opko Health, Inc. OPK | $1.2 billion | n/a | -6.2% | -8.2% | -11.5% | 0.29 | n/a |
| Rapport Therapeutics, Inc. RAPP | $1.2 billion | n/a | n/a | n/a | n/a | 0.00 | n/a |
| Amphastar Pharmaceuticals, Inc. AMPH | $1.1 billion | 15.93 | 10.2% | 15.7% | 1.0% | 0.79 | n/a |
| Harrow, Inc. HROW | $1.1 billion | n/a | -244.9% | -1.0% | 21.1% | 19.24 | n/a |
| Janux Therapeutics, Inc. JANX | $1.1 billion | n/a | -11.1% | -598.1% | 5,367.0% | 0.00 | n/a |
| Mannkind Corp. MNKD | $1.1 billion | n/a | n/a | 2.3% | 30.5% | n/a | n/a |
| Inhibrx Biosciences, Inc. INBX | $1.1 billion | n/a | n/a | n/a | n/a | n/a | n/a |
| Rigel Pharmaceuticals Inc. RIGL | $961 million | 3.15 | 75.7% | 31.5% | 3.3% | 0.09 | n/a |
| Kura Oncology, Inc. KURA | $940 million | n/a | -612.8% | -411.9% | n/a | 0.20 | n/a |
| QuidelOrtho Corp. QDEL | $940 million | n/a | -59.1% | -30.8% | -2.5% | 1.63 | n/a |
| Monte Rosa Therapeutics, Inc. GLUE | $928 million | n/a | -33.1% | -633.0% | -83.9% | 0.00 | n/a |
| Cryoport, Inc. CYRX | $926 million | n/a | n/a | n/a | n/a | 0.38 | n/a |
| MeiraGTx Holdings plc MGTX | $914 million | 13.67 | 36.6% | 46.3% | 948.3% | 0.46 | n/a |
| Verastem, Inc. VSTM | $874 million | n/a | n/a | n/a | n/a | 1.48 | n/a |
| Arbutus Biopharma Corp. ABUS | $846 million | 5.42 | 59.2% | 82.0% | 1,078.8% | 0.00 | n/a |
| Nektar Therapeutics NKTR | $799 million | n/a | -17.4% | -257.8% | -27.2% | 0.00 | n/a |
| Collegium Pharmaceutical, Inc. COLL | $780 million | 19.37 | 15.4% | 19.5% | 14.3% | 3.50 | n/a |
| Ardelyx, Inc. ARDX | $772 million | n/a | -37.4% | -7.9% | 16.8% | 1.69 | n/a |
| Wave Life Sciences, Inc. WVE | $715 million | n/a | -52.4% | -320.9% | n/a | 0.00 | n/a |
| Design Therapeutics, Inc. DSGN | $694 million | n/a | -35.1% | n/a | n/a | 0.00 | n/a |
| Gyre Therapeutics, Inc. GYRE | $676 million | n/a | -29.7% | -14.0% | 16.8% | 0.00 | n/a |
| Lexicon Pharmaceuticals, Inc. LXRX | $666 million | n/a | -35.0% | -131.4% | -29.0% | 0.29 | n/a |
| Myriad Genetics Inc. MYGN | $637 million | n/a | -37.1% | -12.2% | -3.2% | 0.40 | n/a |
| Zevra Therapeutics, Inc. ZVRA | $614 million | 11.02 | 26.8% | 60.5% | 119.4% | 0.00 | n/a |
| Geron Corp. GERN | $608 million | n/a | n/a | n/a | n/a | 0.55 | n/a |
| Ironwood Pharmaceuticals Inc. IRWD | $598 million | 4.70 | n/a | 60.1% | 26.2% | n/a | n/a |
| CorMedix Inc. CRMD | $593 million | 3.57 | 40.6% | 47.0% | n/a | 0.00 | n/a |
| Aclaris Therapeutics, Inc. ACRS | $559 million | n/a | -60.8% | -1,050.2% | -51.0% | 0.00 | n/a |
| Puma Biotechnology, Inc. PBYI | $538 million | 20.26 | 19.3% | 13.2% | -2.9% | 0.00 | n/a |
| Arvinas, Inc. ARVN | $516 million | 79.05 | 1.7% | -5.7% | -15.0% | 0.00 | n/a |
| Phathom Pharmaceuticals, Inc. PHAT | $507 million | n/a | n/a | -9.3% | 86.8% | n/a | n/a |
| Aquestive Therapeutics, Inc. AQST | $505 million | n/a | n/a | -97.5% | 22.6% | n/a | n/a |
| CytomX Therapeutics, Inc. CTMX | $496 million | n/a | -26.4% | -476.2% | -87.0% | 0.00 | n/a |
| Evolus, Inc. EOLS | $495 million | n/a | n/a | -5.9% | 13.9% | n/a | n/a |
| Monopar Therapeutics MNPR | $483 million | n/a | n/a | n/a | n/a | 0.00 | n/a |
| Crescent Biopharma, Inc. CBIO | $391 million | n/a | n/a | n/a | n/a | 0.00 | n/a |
120 companies share its SEC industry code (Pharmaceutical Preparations); the rest are the names nearest in size in its wider industry, Pharmaceutical Products, one of the Fama-French 48 industries, a published grouping of SEC industry codes.
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By market capitalisation; a click on a heading sorts by it, largest first, and a second click turns it round. Each figure is the same arithmetic as the ratio box above, on each company's own filings and latest close; a name marked * is a foreign company that files once a year, on its latest fiscal year.Filings
| Filing | Period | Filed | Where |
|---|---|---|---|
| 10-Q | 30 September 2026 | 27 October 2026 | EDGAR |
| 10-Q | 30 June 2026 | 30 July 2026 | EDGAR |
| 10-K/A | 31 December 2025 | 30 April 2026 | EDGAR |
| 10-Q | 31 March 2026 | 28 April 2026 | EDGAR |
| 10-K | 31 December 2025 | 26 February 2026 | EDGAR |
| 10-Q | 30 September 2025 | 10 November 2025 | EDGAR |
| 10-Q | 30 June 2025 | 30 July 2025 | EDGAR |
| 10-Q | 31 March 2025 | 8 May 2025 | EDGAR |
| 10-K/A | 31 December 2024 | 29 April 2025 | EDGAR |
| 10-K | 31 December 2024 | 4 March 2025 | EDGAR |