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Genmab A/S (GMAB)

Genmab is a Danish biotechnology company that creates antibody medicines for cancer and other serious diseases. It was incorporated on 11 June 1998 as a shelf company under Danish law, commenced operations in February 1999 and was converted into a public limited liability company on 31 May 1999. The shares are listed on Nasdaq Copenhagen and the American depositary shares on Nasdaq in the US, and the domicile is Carl Jacobsens Vej 30 in Valby, Denmark. Deal figures are stated in US dollars.

Genmab A/S

Genmab is a Danish biotechnology company that creates antibody medicines for cancer and other serious diseases. It was incorporated on 11 June 1998 as a shelf company under Danish law, commenced operations in February 1999 and was converted into a public limited liability company on 31 May 1999. The shares are listed on Nasdaq Copenhagen and the American depositary shares on Nasdaq in the US, and the domicile is Carl Jacobsens Vej 30 in Valby, Denmark. Deal figures are stated in US dollars.

Its own medicines

Two co-owned products are on the market. Epcoritamab, sold as EPKINLY in countries including the US and Japan and as TEPKINLY in the EU, is a bispecific antibody approved for the treatment of multiple B-cell malignancies and is developed and commercialised in collaboration with AbbVie. Tivdak, or tisotumab vedotin, is an antibody-drug conjugate approved in territories including the US, Europe and Japan for adult patients with recurrent or metastatic cervical cancer with disease progression on or after prior systemic therapy. Genmab became a commercial-stage company with the launch of Tivdak in 2021, began commercialising EPKINLY with AbbVie in 2023, and launched Tivdak in Japan and Germany in 2025.

The pipeline

Five proprietary products or product candidates are in active clinical development, counting programmes where Genmab retains at least 50% of product rights. The company states that its current priorities are epcoritamab, Rina-S and petosemtamab. Rina-S, an antibody-drug conjugate aimed at folate receptor alpha, is in Phase III for platinum-resistant ovarian cancer, platinum-sensitive ovarian cancer and endometrial cancer. Petosemtamab, which binds EGFR and the receptor known as LGR5, is in Phase III for newly diagnosed and recurrent or metastatic head and neck squamous cell carcinoma. Both are wholly owned by Genmab. In December 2025 further development of acasunlimab was discontinued.

The royalty book

Six approved medicines created by Genmab or built with its technology are sold by other companies, which pay royalties and milestones while Genmab does none of the commercial work. Four are marketed by J&J: daratumumab as DARZALEX, amivantamab as RYBREVANT, teclistamab as TECVAYLI and talquetamab as TALVEY. Novartis markets ofatumumab as Kesimpta and Amgen markets teprotumumab as TEPEZZA. BIZENGRI, licensed to Partner Therapeutics for the US, joined the royalty portfolio through the acquisition of Merus. Under the 2012 daratumumab agreement Genmab recorded a $55.0 million upfront fee, and its tiered royalties run from 12% on annual net sales up to $750 million to 20% on net sales above $3.0 billion.

The two partner deals

The June 2020 AbbVie agreement brought a $750 million upfront payment, with up to $1.06 billion in further development, regulatory and sales milestones now contractually available. Genmab is the principal for epcoritamab sales in the US and Japan, takes tiered royalties between 22% and 26% elsewhere, and otherwise splits profits and development costs with AbbVie on a 50:50 basis. On Tivdak, from 1 January 2025 Genmab took sole responsibility for development and commercialisation in Europe and all other regions excluding the US and China, records those sales, and pays Pfizer royalties in the low teens on them. It continues to co-promote Tivdak with Pfizer in the US, where Pfizer leads operations.

Platforms and facilities

The antibody platforms are DuoBody for bispecific antibodies, HexaBody to increase potency through hexamerization, DuoHexaBody which does the same for bispecifics, HexElect which combines two HexaBody molecules for more selective binding, and the ADC platforms bought with ProfoundBio in May 2024, with further platforms gained from Merus. Genmab manufactures nothing itself, relying on collaboration partners and contract manufacturers for clinical and commercial supply, and has no involvement with manufacturing the partner-marketed medicines. Material leased sites include the 175,130 square foot corporate headquarters in Valby, laboratory and office space in Ballerup, three sites in Utrecht, two in Plainsboro, New Jersey, and offices in Tokyo and Suzhou.

From Genmab's annual report on Form 20-F for the year ended 31 December 2025. That filing answers Item 5, the operating and financial review, with page references to a document attached to it rather than with text, so this description is written from Item 4, the business description, alone. The filing

Compare with another name

Genmab A/S files a 20-F with the SEC once a year, in US dollars. In the year to 31 December 2025 it reported revenue of USD 3,720 million, up 19.2% on the year before. Its profit was USD 963 million, down 15.0%, and diluted earnings per share USD 15.37.

Genmab (GMAB) in brief

Genmab (GMAB) reported revenue of USD 3.7 billion for the year to 31 December 2025, up 19.2% on the year before.
Read moreProfit attributable to shareholders was USD 963 million and diluted earnings per share USD 15.37. Revenue was USD 3.1 billion in 2024 and USD 2.4 billion in 2023. Profit attributable to shareholders in the same years was USD 1.1 billion and USD 631 million. At the close of 10 November 2026 the market cap of Genmab was $34.7 billion, 35.2 times its earnings for 2025.

The share in the US

Last close$54.08 on 10 November 2026
52-week range$23.85 (2 June 2026) to $57.35 (28 October 2026)
Over one yearup 86.1%
Market cap$34.7 billion: 64,238,408 shares outstanding at 31 December 2025 (20-F), each US share standing for 0.1 of an ordinary share
P/E, latest fiscal year35.2: the last close over diluted EPS for the year to Dec 2025, USD 15.37 per ordinary share times 0.1, USD 1.54 per US share. The company reports once a year, so this is the latest fiscal year, not the last four quarters.

US dollars per share as it trades in the US; the market cap and the P/E are worked out here, not filed. Prices from IEX, for splits.

Ratios

From the latest annual report, the year to Dec 2025, in dollars

ROE16.5%
ROCE9.6%
Operating margin28.6%
Net margin25.9%
FCF margin30.9%
Interest cover3.96
Debt to equity0.90
Cash conversion1.23
Share count, last 12 months-2.1%
Sales CAGR, 3 yearsn/a
Profit CAGR, 3 yearsn/a
EPS$1.54

At the close of 10 November 2026

Price$54.08
Market cap$34.7 billion
Stock P/E35.19
Price to book5.94
EV / EBITDAn/a
Dividend yieldn/a
Market cap / sales9.34
52-week high$57.35
52-week low$23.85
Price, 1 year86.1%
Price CAGR, 3 yearsn/a
Price CAGR, 5 yearsn/a
Worked from the filed figures; hover a name for the formula.
Read moreThe priced ones use the latest price, the last regular-hours trade on IEX. Debt to equity here stands on the borrowings total Genmab A/S states in its annual report, never added up from its parts; lease liabilities are a separate line. Nothing here is a valuation or a view.
GMABgreeksoup.ai
Daily prices to 10 November 2026, adjusted for splits; from 28 September 2026 each day's price is the last regular-hours trade on IEX.
Read moreData provided for free by IEX. By accessing or using IEX Historical Data, you agree to the IEX Historical Data Terms of Use. Day by day for the last three years; before that one point a week, carrying the week's last close and its average daily volume, so a volume bar means the same thing across the whole series; the bars sit under the price on their own scale, on the right. The moving averages need consecutive days and are drawn from the daily part. This company reports once a year, so every view here moves once a year, on the day each annual report was filed, and holds until the next. P/E is the close over the year's EPS per US share: the EPS as filed, times the 0.1 of an ordinary share one US share stands for. Sales and margin are each year's revenue and its operating margin. EV/EBITDA, price to book and market cap to sales set the close against that year's balance sheet and its share count per US share. The dashed line is the median over the range shown. Drawn in your browser; the range and overlay you pick are remembered here only.

The public record on GMAB

Dividendsno dividend in its filings for fiscal 2017 onward
Filings66 in twelve months: 64 reports on Form 6-K, most often capital Increase in Genmab as a Result of Employee Warrant Exercise (7); major Shareholder Announcement (6); transactions with Shares and Linked Securities in Genmab A/S Made by Managerial Employees and Their Closely Associated Persons (5); grant of Restricted Stock Units and Warrants to Employees in Genmab (4); transactions in Connection with Share Buy-back Program (3)
Planned insider sales1 Form 144 notice in twelve months, $704,327; latest 10 November 2026
Options tapeput/call 0.27 by open interest at the 10 November 2026 close; the straddle prices a 5.7% move to 20 November 2026
13F holders294 funds reported a position for the quarter to 30 June 2026; largest Paradigm Biocapital Advisors LP
Congress0 House trades disclosed in six months
Short interest9.7 million shares short, 1.24 days to cover at 30 October 2026

Income statement (profit and loss), 3 fiscal years

Year toDec 2023Dec 2024Dec 2025
Revenue2,3903,1213,720
Cost of sales33.0143238
Research and development1,1071,4141,606
Selling, general and administrative478549626
Operating profit7729721,065
Finance costs254291269
Profit before tax8171,3261,204
Income tax186193241
Profit for the year6311,133963
Profit attributable to shareholders6311,133963
Filing20-F20-F20-F
USD million, from each year's annual report on the SEC's EDGAR, linked in the last row, on the IFRS tags the company filed.
Read moreA line the company does not file under the standard tag is left out rather than estimated. Profit attributable to shareholders is the profit for the year; the company reports no minority interests. Profit for the year includes the part that belongs to minority shareholders; profit attributable to shareholders is the part EPS is struck on. Each year links to its own page.
Year toDec 2023Dec 2024Dec 2025
Diluted EPS9.5817.5315.37
Basic EPS9.6717.6615.50
Filing20-F20-F20-F

USD per ordinary share, as filed. One US-listed share can stand for more or fewer ordinary shares; the P/E above puts the two on the same basis.

Revenue by region

Dec 2023Dec 2024Dec 2025Share
of the parts, latest year
DK2,3292,8683,32689.4%
Japan6.01222135.7%
United States55.01311804.8%
Netherlands0.00.01.0under 0.1%
China0.00.00.0n/a
DKJapanUnited StatesNetherlands FY2025
2,390Dec 20233,121Dec 20243,720Dec 2025

USD million; hover a block for its figure and share; a part named with years is one the company split its revenue into only then

USD million, from the latest 20-F, in the company's own words. A year is shown only where the parts add up to the revenue above.

Cash flow statement

Year toDec 2023Dec 2024Dec 2025
Cash from operations1,0711,1261,186
Purchase of property, plant and equipment53.027.037.0
Free cash flow1,0181,0991,149
Cash from investing-185-1,447-5,643
Cash from financing-89.0-5664,789
Filing20-F20-F20-F
USD million, from the cash flow statement as filed.
Read morePurchase of property, plant and equipment is the cash line as filed; purchases of intangible assets and acquisitions are not in it. Free cash flow is cash from operations less that purchase, arithmetic on the two filed lines. Cash from investing and from financing are the company's own section totals, below zero where cash went out. Buybacks are the cash paid for the company's own shares.

Balance sheet at year end

Year toDec 2023Dec 2024Dec 2025
Funded by
Equity attributable to shareholders4,6875,1375,847
Borrowings, as filed0.00.05,274
Lease liabilities114144152
Other liabilities4311,1331,600
Total equity and liabilities5,2326,41412,873
Owned
Property, plant and equipment142137153
Goodwill0.0355355
Other intangible assets15.01,7289,123
Cash and cash equivalents2,2041,3801,715
Trade and other receivables7339231,112
Inventories8.09.018.0
Other assets2,1301,882397
Total assets5,2326,41412,873
Filing20-F20-F20-F
USD million, at each fiscal year end.
Read moreBoth totals are the company's own; other liabilities and other assets are each total less the rows shown. Borrowings is the company's own stated total where it files one; it is never added up from its parts here.

Ratios on the filed lines

Year toDec 2023Dec 2024Dec 2025
Operating margin32.3%31.1%28.6%
Net margin26.4%36.3%25.9%
Free cash flow margin42.6%35.2%30.9%
Return on year-end equity13.5%22.1%16.5%
Effective tax rate22.8%14.6%20.0%
Filing20-F20-F20-F

Arithmetic on the filed lines of the same year: margins over revenue, return on equity as profit attributable to shareholders over year-end equity, tax over profit before tax.

Questions

What was Genmab's revenue in 2025?

Genmab (GMAB) reported revenue of USD 3.7 billion for the year to 31 December 2025, up 19.2% on the year before.

How much did Genmab earn in 2025?

Profit attributable to shareholders was USD 963 million for the year to 31 December 2025, and diluted earnings per share USD 15.37.

What is Genmab's P/E ratio?

At the close of 10 November 2026, Genmab traded at 35.2 times its earnings for 2025.

What is Genmab's market cap?

The market cap of Genmab was $34.7 billion at the close of 10 November 2026.

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TTM
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Johnson & Johnson JNJ$675.9 billion42.5419.7%n/a7.8%0.551.9%
AbbVie Inc. ABBV$519.4 billion50.58n/a32.2%10.7%n/a2.4%
Merck & Co., Inc. MRK$364.8 billion152.575.5%n/a4.9%1.202.3%
Novartis AG NVS *$311.5 billion22.8330.3%n/a8.4%0.622.5%
AstraZeneca PLC AZN *$289.7 billion28.5621.0%23.4%8.6%0.571.7%
Abbott Laboratories ABT$191.3 billion41.219.2%13.8%10.0%0.612.3%
Novo Nordisk A/S NVO *$181.7 billion11.8452.8%41.3%6.4%0.674.3%
Pfizer Inc. PFE$167.3 billion41.944.5%n/a1.3%0.705.9%
Vertex Pharmaceuticals Inc. VRTX$138.9 billion35.2419.0%33.2%10.5%0.22n/a
Bristol-Myers Squibb Co. BMY$128.4 billion13.9239.5%22.6%4.2%1.834.0%
Sanofi SNY *$117.6 billion13.5710.9%n/a6.2%0.264.6%
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TTM
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Eli Lilly & Co. LLY$1.35 trillion46.5168.5%n/a45.5%1.230.4%
Johnson & Johnson JNJ$675.9 billion42.5419.7%n/a7.8%0.551.9%
AbbVie Inc. ABBV$519.4 billion50.58n/a32.2%10.7%n/a2.4%
Merck & Co., Inc. MRK$364.8 billion152.575.5%n/a4.9%1.202.3%
Novartis AG NVS *$311.5 billion22.8330.3%n/a8.4%0.622.5%
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Gilead Sciences, Inc. GILD$212.1 billionn/a-29.6%-7.6%6.5%2.011.9%
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Harmony Biosciences Holdings, Inc. HRMY$2.0 billion11.1116.7%22.2%19.8%0.14n/a
Eton Pharmaceuticals, Inc. ETON$1.9 billion44.3657.4%28.8%100.6%0.27n/a
Zenas BioPharma, Inc. ZBIO$1.9 billionn/an/an/an/a1.41n/a
Biocryst Pharmaceuticals Inc. BCRX$1.9 billionn/an/a-30.1%60.3%n/an/a
Agios Pharmaceuticals, Inc. AGIO$1.9 billionn/a-38.1%-297.7%214.4%0.00n/a
Trulieve Cannabis Corp. TRLV$1.9 billionn/a-57.8%-25.6%-9.1%0.37n/a
Generate Biomedicines, Inc. GENB$1.8 billionn/an/an/an/a0.00n/a
Stoke Therapeutics, Inc. STOK$1.8 billionn/a-69.0%-913.1%-86.3%0.00n/a
Sarepta Therapeutics, Inc. SRPT$1.8 billionn/a-7.5%-2.5%-18.9%0.56n/a
Nurix Therapeutics, Inc. NRIX$1.7 billion6.8730.5%41.3%738.8%0.000.0%
Novavax Inc. NVAX$1.7 billionn/an/a-21.2%-61.3%n/an/a
Immunocore Holdings plc IMCR$1.7 billionn/a-7.7%-6.8%13.1%0.940.0%
Ultragenyx Pharmaceutical Inc. RARE$1.6 billionn/an/a-64.0%15.8%n/an/a
Precigen, Inc. PGEN$1.6 billion129.2029.1%21.4%n/a1.12n/a
ANI Pharmaceuticals Inc. ANIP$1.6 billion14.0318.3%16.0%25.9%0.95n/a
uniQure N.V. QURE$1.6 billionn/a-79.0%-1,001.7%28.0%0.17n/a
Intellia Therapeutics, Inc. NTLA$1.6 billionn/a-69.5%-821.2%-8.1%0.12n/a
Nuvation Bio Inc. NUVB$1.5 billionn/a-59.6%-61.2%654.2%1.25n/a
Pacira BioSciences, Inc. PCRX$1.5 billion39.235.3%4.8%3.7%0.41n/a
Ocular Therapeutix, Inc. OCUL$1.5 billionn/a-74.1%-680.9%-9.7%0.17n/a
Phibro Animal Health Corp. PAHC$1.4 billion13.8524.6%12.5%10.1%1.761.4%
Korsana Biosciences, Inc. KRSA$1.4 billionn/an/an/an/a0.00n/a
Taysha Gene Therapies, Inc. TSHA$1.4 billionn/a-38.6%-2,792.3%-32.3%0.13n/a
Avalyn Pharma Inc. AVLN$1.4 billionn/an/an/an/a0.04n/a
Innoviva, Inc. INVA$1.4 billion9.5917.0%38.8%12.8%0.23n/a
Mannkind Corp. MNKD$1.4 billionn/an/a-2.9%31.7%n/an/a
Inhibrx Biosciences, Inc. INBX$1.3 billionn/an/an/an/an/an/a
Opko Health, Inc. OPK$1.3 billionn/a-13.3%-25.5%-21.9%0.43n/a
Cronos Group Inc. CRON$1.3 billion20.065.4%3.4%55.8%0.00n/a
Rapport Therapeutics, Inc. RAPP$1.2 billionn/an/an/an/a0.00n/a
Omeros Corp. OMER$1.2 billionn/an/an/an/an/an/a
UroGen Pharma Ltd. URGN$1.2 billionn/an/a-12.4%159.3%n/an/a
Amphastar Pharmaceuticals, Inc. AMPH$1.2 billion13.2812.1%18.7%3.1%0.75n/a
Harrow, Inc. HROW$1.1 billionn/a-97.6%-2.0%21.3%10.03n/a
Cryoport, Inc. CYRX$1.1 billionn/a-7.8%-20.0%1.1%0.39n/a
Odyssey Therapeutics, Inc. ODTX$957 millionn/an/an/an/a0.00n/a
Aktis Oncology, Inc. AKTS$934 millionn/an/an/an/a0.00n/a
MeiraGTx Holdings plc MGTX$906 million13.5436.6%46.3%948.3%0.46n/a
Monte Rosa Therapeutics, Inc. GLUE$896 millionn/a-26.4%-214.5%-61.3%0.00n/a
Syndax Pharmaceuticals Inc. SNDX$851 millionn/an/a-61.7%159.5%n/an/a
Lexicon Pharmaceuticals, Inc. LXRX$838 millionn/a-38.1%-147.4%-45.6%0.32n/a
Rigel Pharmaceuticals Inc. RIGL$827 million2.8369.0%26.3%2.2%0.02n/a
Verastem, Inc. VSTM$824 millionn/an/an/an/a11.82n/a
Ironwood Pharmaceuticals Inc. IRWD$797 million5.35n/a62.9%18.1%n/an/a
QuidelOrtho Corp. QDEL$791 millionn/a-20.6%-4.9%-4.5%1.64n/a
Ginkgo Bioworks Holdings, Inc. DNA$775 millionn/a-63.9%-242.5%-44.2%0.00n/a
Nektar Therapeutics NKTR$770 millionn/a-17.4%-257.8%-27.2%0.00n/a
Arbutus Biopharma Corp. ABUS$762 million3.38256.5%81.1%1,142.6%0.00n/a
Collegium Pharmaceutical, Inc. COLL$760 million24.4612.9%15.2%7.7%3.65n/a
Ardelyx, Inc. ARDX$754 millionn/a-33.8%-7.7%17.6%1.54n/a
Janux Therapeutics, Inc. JANX$736 millionn/a-11.0%-599.3%132.9%0.00n/a
Zevra Therapeutics, Inc. ZVRA$709 million9.8632.7%60.8%75.1%0.00n/a
Kura Oncology, Inc. KURA$695 millionn/a-1,630.7%-394.3%n/a0.55n/a
Design Therapeutics, Inc. DSGN$679 millionn/a-36.6%n/an/a0.00n/a
Wave Life Sciences, Inc. WVE$671 millionn/a-52.4%-320.9%n/a0.00n/a
Geron Corp. GERN$627 millionn/an/an/an/a0.53n/a
Aclaris Therapeutics, Inc. ACRS$626 millionn/a-47.7%-1,414.0%-59.3%0.00n/a
Myriad Genetics Inc. MYGN$541 millionn/a-48.0%-14.3%-2.6%0.45n/a
Monopar Therapeutics MNPR$481 millionn/an/an/an/a0.00n/a
Arvinas, Inc. ARVN$452 millionn/a-1.8%-12.1%-11.8%0.00n/a
Gyre Therapeutics, Inc. GYRE$452 millionn/a-37.5%-20.6%13.5%0.00n/a
Evolus, Inc. EOLS$450 millionn/an/a-4.8%13.9%n/an/a
Phathom Pharmaceuticals, Inc. PHAT$442 millionn/an/a-9.3%86.8%n/an/a
Aquestive Therapeutics, Inc. AQST$442 millionn/an/a-114.1%12.5%n/an/a
CytomX Therapeutics, Inc. CTMX$434 millionn/a-30.0%-676.5%-87.7%0.00n/a
Puma Biotechnology, Inc. PBYI$420 million17.6516.3%11.3%9.4%0.00n/a
CorMedix Inc. CRMD$416 million2.5040.6%47.0%n/a0.00n/a
Crescent Biopharma, Inc. CBIO$386 millionn/an/an/an/a0.00n/a
Canopy Growth Corp. CGC$251 millionn/an/a-54.2%10.7%0.38n/a
Atrium Therapeutics, Inc. RNA$141 millionn/an/an/an/an/an/a
Gossamer Bio, Inc. GOSS$69 millionn/an/a-140.0%78.0%n/an/a
124 companies share its SEC industry code (Pharmaceutical Preparations); the rest are the names nearest in size in its wider industry, Pharmaceutical Products, one of the Fama-French 48 industries, a published grouping of SEC industry codes.
Read moreBy market capitalisation; a click on a heading sorts by it, largest first, and a second click turns it round. Each figure is the same arithmetic as the ratio box above, on each company's own filings and latest close; a name marked * is a foreign company that files once a year, on its latest fiscal year.

Annual reports on EDGAR

FormYear toFiled
20-F31 December 202517 February 2026EDGAR
20-F31 December 202412 February 2025EDGAR
20-F31 December 202314 February 2024EDGAR
20-F31 December 202222 February 2023EDGAR
20-F31 December 202116 February 2022EDGAR
20-F31 December 202029 March 2021EDGAR
20-F31 December 201930 March 2020EDGAR