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Stock research / United States / KRYS · Biological Products, (No Diagnostic Substances) · Nasdaq

Krystal Biotech, Inc. (KRYS)

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Krystal Biotech, Inc. (KRYS) reported revenue of $119 million for Q2 FY2026, the quarter ended 30 June 2026, up 24.1% on the same quarter a year earlier. Net income was $55 million, up 42.9% on the year, and diluted earnings per share $1.79. The figures are the company's own, from the 10-Q it filed with the SEC on 3 August 2026.

Revenue$119 millionup 24.1%
Net income$55 millionup 42.9%
Diluted EPS$1.79
QuarterQ2 FY2026ended 30 June 2026

Krystal Biotech (KRYS) in brief

Krystal Biotech (KRYS) reported revenue of $389 million for fiscal 2025, the year ended 31 December 2025, up 33.9% on the year before.
Read moreNet income was $205 million and diluted earnings per share $6.84. Revenue was $291 million in fiscal 2024, $51 million in fiscal 2023, $0 million in fiscal 2022 and $0 million in fiscal 2021. Net income in the same years was $89 million, $11 million, a loss of $140 million and a loss of $70 million. Over the twelve months to 30 June 2026, Krystal Biotech reported revenue of $440 million and net income of $241 million. Krystal Biotech had 30 million shares outstanding at the latest filed count. At 30 June 2026 it carried $0 million of debt and $428 million of cash. At the close of 8 October 2026 the market cap of Krystal Biotech was $9.7 billion, 41.0 times its earnings over the last twelve months.

Ratios

From the filings

ROE17.8%
ROCE14.6%
Operating margin44.9%
Net margin54.8%
FCF margin58.5%
Interest covern/a
Debt to equity0.00
Cash conversion1.13
Share count, 1 year2.3%
Sales CAGR, 3 yearsn/a
Profit CAGR, 3 yearsn/a
EPS, TTM$7.98

At the close of 8 October 2026

Price$327.30
Market cap$9.7 billion
Stock P/E41.02
Price to book7.13
EV / EBITDAn/a
Dividend yieldn/a
Market cap / sales21.99
52-week high$378.15
52-week low$181.47
Price, 1 year74.9%
Price CAGR, 3 years40.9%
Price CAGR, 5 years44.7%
Worked from the filed figures; hover a name for the formula.
Read moreThe priced ones use the latest daily close from SimFin. Krystal Biotech, Inc.'s balance sheet shows no borrowings, so debt here is nil; lease liabilities are a separate line. Nothing here is a valuation or a view.
KRYSgreeksoup.ai
Daily closes to 8 October 2026, adjusted for splits; prices from SimFin.
Read moreDay by day for the last three years; before that one point a week, carrying the week's last close and its average daily volume, so a volume bar means the same thing across the whole series; the bars sit under the price on their own scale, on the right. The moving averages need consecutive days and are drawn from the daily part. P/E is the close over the trailing four quarters' EPS as filed at each filing date, on the current share count; the dashed line is the median over the range shown. Sales and margin are quarterly revenue and the operating margin from the tables above. EV/EBITDA, price to book and market cap to sales use the latest filed balance sheet and share count at each date. Before the quarters on file begin, P/E, price to book and market cap to sales stand on each annual report from the day it was filed. Drawn in your browser; the range and overlay you pick are remembered here only.

The public record on KRYS

Filings17 in twelve months: 10 current reports (8-K), about 4 results of operations; 2 other events; 2 regulation fd disclosure; 1 shareholder vote; 1 officer or director change
Planned insider sales19 Form 144 notices in twelve months, $94.6 million; latest 4 September 2026
Options tapeput/call 0.49 by open interest at the 8 October 2026 close; the straddle prices a 4.7% move to 16 October 2026
13F holders7 of the followed funds hold it; largest FMR LLC; 3 Schedule 13D or 13G filings in twelve months
Insider trading142 sales and 0 purchases on Form 4 in twelve months
Congress0 House trades disclosed in six months
Short interest3.2 million shares short, 13.23 days to cover at 15 September 2026
Documentsthe 10-K, the 10-Qs, the proxy and 4 earnings press releases, each linked

Quarterly results, the last 12 quarters

Q3 FY2023Q4 FY2023 *Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024 *Q1 FY2025 †Q2 FY2025 †Q3 FY2025Q4 FY2025 *Q1 FY2026Q2 FY2026
Revenue8.642.145.270.383.891.188.296.097.8107116119
R&D10.611.411.015.613.513.514.314.414.614.815.314.5
SG&A23.724.826.127.628.731.332.635.137.641.341.039.9
Operating income-26.03.1-6.78.622.441.436.339.441.444.453.758.4
Operating margin-304%7%-15%12%27%45%41%41%42%41%46%49%
Pre-tax income80.7n/a0.916.029.848.643.646.848.051.161.466.1
Tax rate0%n/a0%3%9%6%18%18%-65%-1%9%17%
Net income80.78.70.915.627.245.535.738.379.451.455.954.8
Net margin944%21%2%22%32%50%41%40%81%48%48%46%
Diluted EPS$2.79$0.30$0.03$0.53$0.91$1.53$1.20$1.29$2.66$1.70$1.83$1.79
Operating cash flow-21.2-7.215.9-4.258.952.831.052.739.777.580.474.8
Capital expenditure1.81.81.31.11.00.86.21.91.72.17.13.6
Free cash flow-23.0-9.114.6-5.357.852.024.850.838.075.473.271.2
Shares outstanding28m28m29m29m29m29m29m29m29m29m29m30m
Filing10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q
Each quarter as filed, linked to its filing.
Read more* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS and diluted share count are from the company's results press release for that quarter, used where the release gives the same revenue and net income as the table. A quarter marked † is shown as the company last restated it in a later filing, so it compares with the quarters around it on one basis; rest on a figure for the one first filed. EPS is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

Income statement (profit and loss), 5 fiscal years and the trailing twelve months

FY2021FY2022FY2023FY2024FY2025TTM
Revenue0.00.050.7291389440
Research and development27.942.546.453.658.059.2
Selling, general and administrativen/a77.798.4114147160
Operating income-68.3-145-11065.7161198
Operating marginn/an/a-216.4%22.6%41.5%44.9%
Interest expense1.50.00.0n/an/an/a
Pre-tax income-69.6-14012.995.4189227
Income tax0.00.02.06.2-15.4-14.8
Effective tax raten/an/a15.2%6.5%-8.1%-6.6%
Net income-69.6-14010.989.2205241
Net marginn/an/a21.6%30.7%52.6%54.8%
Diluted EPS-$3.13-$5.49$0.39$3.00$6.84$7.98
Filing10-K10-K10-K10-K10-K
From each year's 10-K, linked; TTM is the last four quarters.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow and capital returned

FY2021FY2022FY2023FY2024FY2025TTM
Operating cash flow-47.9-101-88.8123201272
Capital expenditure68.353.011.84.212.014.6
Free cash flow-116-154-101119189258
Free cash flow marginn/an/a-198.4%41.0%48.5%58.5%
Cash from investing-227-11482.6-163-58.4-218
Cash from financing34835.320327.08.724.0
Depreciation and amortisation2.84.1n/an/an/an/a
Share-based compensation15.333.239.949.154.554.7
Diluted shares, weighted22m25m28m30m30m31m
Shares outstanding at period end25m26m28m29m29m30m
Filing10-K10-K10-K10-K10-K
Cash paid in the year, from the cash flow statement.
Read moreThe dividend per share is as declared. Diluted shares are the weighted average for the year; a falling count is the buybacks net of issuance. TTM sums the last four quarters; the share counts are the latest quarter's.

Balance sheet at year end

FY2021FY2022FY2023FY2024FY2025TTM
Funded by
Shareholders' equity5945227799461,2201,359
Debtn/a0.00.00.00.00.0
Operating lease liabilities7.07.46.66.07.67.0
Other liabilities25.728.833.1103107134
Total liabilities and equity6265588181,0561,3341,501
Owned
Fixed assets112162161155151154
Investments161222236405460675
Cash and equivalents341162358345496428
Receivablesn/a0.042.0105127139
Inventoryn/a0.07.026.540.545.6
Other assets11.513.014.019.859.359.7
Total assets6265588181,0561,3341,501
Filing10-K10-K10-K10-K10-K
At the fiscal year end; the TTM column is the latest quarter end.
Read moreBoth totals are the company's own. Other liabilities is the filed total less the rows above it: payables, deferred revenue, taxes, borrowings the rows above do not carry and the rest; other assets is the same on the other side. Investments add the current and non-current lines as filed. Debt is the company's own stated total where it files one, otherwise its long-term debt with the current maturities, never parts added together. A row is left blank in a year where the lines shown overlap and the remainder would fall below nil.

Compounded growth

10 years5 years3 yearsTTM
Sales growth, compoundedn/an/an/a22.6%
Profit growth, compoundedn/an/an/a64.6%
Return on equity, averagen/a-2.2%9.2%16.8%
Yearly growth, compounded; TTM is the last four quarters against the four before.
Read moreReturn on equity is net income over shareholders' equity at each year end, averaged over the window (the TTM column is the latest year alone); equity is the parent's shareholders' equity as tagged in the 10-K. Arithmetic on filed numbers, nothing forecast.

Peers: Pharmaceutical Products

CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Amgen Inc. AMGN$220.3 billion25.3274.8%30.0%9.1%4.901.8%
Gilead Sciences, Inc. GILD$182.6 billionn/a-27.4%-8.2%5.5%2.222.1%
Moderna, Inc. MRNA$78.6 billionn/a-46.6%-149.0%-27.6%0.09n/a
argenx SE ARGX *$50.7 billion41.8317.6%n/a89.9%0.00n/a
Biogen Inc. BIIB$32.2 billion38.664.4%10.1%0.3%0.39n/a
BioNTech SE BNTX *$23.1 billionn/a-5.9%-49.0%4.3%0.01n/a
Exelixis, Inc. EXEL$14.7 billion18.5646.7%39.9%9.2%0.00n/a
Neurocrine Biosciences Inc. NBIX$14.4 billion20.7119.1%23.6%34.4%0.00n/a
Halozyme Therapeutics, Inc. HALO$12.5 billion32.79288.1%35.9%41.2%13.50n/a
Bio-Techne Corp. TECH$11.3 billion63.008.6%20.7%-0.4%0.090.4%
Krystal Biotech, Inc. KRYS$9.7 billion41.0217.8%44.9%22.6%0.00n/a
Repligen Corp. RGEN$9.2 billion224.442.0%8.2%16.5%0.26n/a
All 42 in Pharmaceutical Products
CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Eli Lilly & Co. LLY$1.10 trillion39.2578.8%n/a49.6%1.410.5%
Johnson & Johnson JNJ$618.1 billion29.7224.8%n/a8.1%0.442.0%
ABBVIE Inc. ABBV$481.4 billion76.95n/a26.2%10.4%n/a2.5%
Merck & Co., Inc. MRK$351.3 billion113.907.6%n/a4.6%1.292.3%
Novartis AG NVS *$273.1 billion20.0230.3%n/a8.4%0.622.9%
AstraZeneca PLC AZN *$246.3 billion24.2821.0%23.4%8.6%0.612.0%
Amgen Inc. AMGN$220.3 billion25.3274.8%30.0%9.1%4.901.8%
Gilead Sciences, Inc. GILD$182.6 billionn/a-27.4%-8.2%5.5%2.222.1%
Abbott Laboratories ABT$171.6 billion31.8710.6%15.8%8.1%0.582.4%
Novo Nordisk A/S NVO *$170.8 billion11.0652.8%41.3%6.4%0.674.6%
Pfizer Inc. PFE$158.6 billion36.615.1%n/a-0.2%0.716.2%
Vertex Pharmaceuticals Inc. VRTX$127.5 billion29.2921.8%38.0%10.2%0.00n/a
Bristol-Myers Squibb Co. BMY$121.7 billion13.1241.6%24.2%3.1%1.924.2%
Sanofi SNY *$98.1 billion11.2210.9%n/a6.2%0.265.5%
GSK plc GSK *$93.4 billion12.6734.9%24.3%4.1%0.883.6%
Moderna, Inc. MRNA$78.6 billionn/a-46.6%-149.0%-27.6%0.09n/a
Regeneron Pharmaceuticals, Inc. REGN$78.4 billion18.2813.7%24.7%9.3%0.060.5%
Takeda Pharmaceutical Company Limited TAK *$58.5 billionn/a-2.1%0.1%-1.7%0.663.5%
argenx SE ARGX *$50.7 billion41.8317.6%n/a89.9%0.00n/a
Teva Pharmaceutical Industries Ltd. TEVA$45.7 billion65.429.1%9.3%4.1%2.140.0%
IDEXX Laboratories Inc. IDXX$40.5 billion36.0970.7%32.0%12.8%0.60n/a
Biogen Inc. BIIB$32.2 billion38.664.4%10.1%0.3%0.39n/a
Zoetis Inc. ZTS$30.3 billion12.0483.1%n/a1.5%2.872.8%
Roivant Sciences Ltd. ROIV$24.7 billionn/a-6.3%-7,914.8%-67.6%0.00n/a
Genmab A/S GMAB *$23.2 billion23.4516.5%28.6%19.2%0.90n/a
BioNTech SE BNTX *$23.1 billionn/a-5.9%-49.0%4.3%0.01n/a
United Therapeutics Corp. UTHR$22.7 billion19.0620.5%44.4%2.5%0.00n/a
Viatris Inc. VTRS$20.0 billionn/a-2.9%-0.6%4.4%0.812.8%
Exelixis, Inc. EXEL$14.7 billion18.5646.7%39.9%9.2%0.00n/a
Jazz Pharmaceuticals plc JAZZ$14.4 billion15.3419.6%19.5%12.6%0.91n/a
Neurocrine Biosciences Inc. NBIX$14.4 billion20.7119.1%23.6%34.4%0.00n/a
Corcept Therapeutics Inc. CORT$12.8 billion282.247.8%0.8%16.0%0.00n/a
Halozyme Therapeutics, Inc. HALO$12.5 billion32.79288.1%35.9%41.2%13.50n/a
Bio-Techne Corp. TECH$11.3 billion63.008.6%20.7%-0.4%0.090.4%
Elanco Animal Health Inc. ELAN$11.3 billionn/a-3.0%n/a12.0%0.56n/a
Biomarin Pharmaceutical Inc. BMRN$10.6 billion148.351.2%4.4%11.2%0.66n/a
Dr. Reddy’s Laboratories Limited RDY *$10.2 billion22.8511.4%15.0%3.2%0.050.7%
Krystal Biotech, Inc. KRYS$9.7 billion41.0217.8%44.9%22.6%0.00n/a
Repligen Corp. RGEN$9.2 billion224.442.0%8.2%16.5%0.26n/a
Cytokinetics Inc. CYTK$8.6 billionn/an/a-1,046.1%-21.1%n/an/a
Arrowhead Pharmaceuticals, Inc. ARWR$8.6 billionn/a-68.7%-33.8%16.8%1.47n/a
Lantheus Holdings, Inc. LNTH$6.5 billion24.1821.0%19.4%2.3%0.43n/a
11 companies share its SEC industry code (Biological Products, (No Diagnostic Substances)); the rest are the names nearest in size in its wider industry, Pharmaceutical Products, one of the Fama-French 48 industries, a published grouping of SEC industry codes.
Read moreBy market capitalisation; a click on a heading sorts by it, largest first, and a second click turns it round. Each figure is the same arithmetic as the ratio box above, on each company's own filings and latest close; a name marked * is a foreign company that files once a year, on its latest fiscal year.

Filings

FilingPeriodFiledWhere
10-Q30 June 20263 August 2026EDGAR
10-Q31 March 20264 May 2026EDGAR
10-K31 December 202517 February 2026EDGAR
10-Q30 September 20253 November 2025EDGAR
10-Q30 June 20254 August 2025EDGAR
10-Q31 March 20256 May 2025EDGAR
10-K31 December 202419 February 2025EDGAR
10-Q30 September 20244 November 2024EDGAR
10-Q30 June 20245 August 2024EDGAR
10-Q31 March 20246 May 2024EDGAR

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