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Stock research / United States / OPK · Pharmaceutical Preparations · Nasdaq

Opko Health, Inc. (OPK)

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Opko Health, Inc. (OPK) reported revenue of $164 million for Q2 FY2026, the quarter ended 30 June 2026, up 4.3% on the same quarter a year earlier. Net income was -$8 million, and diluted earnings per share $-0.01. The figures are the company's own, from the 10-Q it filed with the SEC on 27 July 2026.

Revenue$164 millionup 4.3%
Net income-$8 million
Diluted EPS$-0.01
QuarterQ2 FY2026ended 30 June 2026

Opko Health (OPK) in brief

Opko Health (OPK) reported revenue of $607 million for fiscal 2025, the year ended 31 December 2025, down 14.9% on the year before.
Read moreNet loss was $226 million and the diluted loss per share $0.30. Revenue was $713 million in fiscal 2024, $863 million in fiscal 2023, $1.0 billion in fiscal 2022 and $1.8 billion in fiscal 2021. Net income in the same years was a loss of $53 million, a loss of $189 million, a loss of $328 million and a loss of $30 million. Over the twelve months to 30 June 2026, Opko Health reported revenue of $588 million and net loss of $73 million. Revenue fell 15.8% a year, compounded, over the five years to fiscal 2025. Opko Health had 746 million shares outstanding at the latest filed count. At 30 June 2026 it carried $349 million of debt and $301 million of cash. At the close of 29 October 2026 the market cap of Opko Health was $1.2 billion.

Ratios

From the filings

ROE-6.2%
ROCE-3.1%
Operating margin-8.2%
Net margin-12.4%
FCF margin-22.8%
Interest cover-1.07
Debt to equity0.29
Cash conversionn/a
Share count, last 12 months-6.0%
Sales CAGR, 3 years-15.5%
Profit CAGR, 3 yearsn/a
EPS, TTM-$0.09

At the close of 29 October 2026

Price$1.67
Market cap$1.2 billion
Stock P/En/a
Price to book1.05
EV / EBITDA31.22
Dividend yieldn/a
Market cap / sales2.12
52-week high$1.73
52-week low$1.10
Price, 1 year16.8%
Price CAGR, 3 years10.7%
Price CAGR, 5 years-15.1%
Worked from the filed figures; hover a name for the formula.
Read moreThe priced ones use the latest price, the last regular-hours trade on IEX. Debt to equity here stands on long-term debt as Opko Health, Inc. files it, with lease liabilities counted separately and never inside it. Nothing here is a valuation or a view.
OPKgreeksoup.ai
Daily prices to 29 October 2026, adjusted for splits; from 28 September 2026 each day's price is the last regular-hours trade on IEX.
Read moreData provided for free by IEX. By accessing or using IEX Historical Data, you agree to the IEX Historical Data Terms of Use. Day by day for the last three years; before that one point a week, carrying the week's last close and its average daily volume, so a volume bar means the same thing across the whole series; the bars sit under the price on their own scale, on the right. The moving averages need consecutive days and are drawn from the daily part. P/E is the close over the trailing four quarters' EPS as filed at each filing date, on the current share count; the dashed line is the median over the range shown. Sales and margin are quarterly revenue and the operating margin from the tables above. EV/EBITDA, price to book and market cap to sales use the latest filed balance sheet and share count at each date. Before the quarters on file begin, P/E, price to book and market cap to sales stand on each annual report from the day it was filed. Drawn in your browser; the range and overlay you pick are remembered here only.

The public record on OPK

Dividendsno dividend in its filings for fiscal 2009 onward
Filings17 in twelve months: 8 current reports (8-K), about 3 results of operations; 2 material agreement; 1 other events; 1 new financial obligation; 1 shareholder vote
Planned insider salesno Form 144 notice in twelve months
Options tapeput/call 0.04 by open interest at the 29 October 2026 close; the straddle prices a 31.1% move to 20 November 2026
13F holders223 funds reported a position for the quarter to 30 June 2026; largest Rubric Capital Management LP
Insider trading0 sales and 34 purchases on Form 4 in twelve months
Congress0 House trades disclosed in six months
Short interest34.0 million shares short, 5.26 days to cover at 15 October 2026
Documentsthe 10-K, the 10-Qs, the proxy and 3 earnings press releases, each linked

Quarterly results, the last 20 quarters

Q3 FY2021Q4 FY2021Q1 FY2022Q2 FY2022Q3 FY2022Q4 FY2022Q1 FY2023Q2 FY2023Q3 FY2023Q4 FY2023Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024Q1 FY2025Q2 FY2025Q3 FY2025Q4 FY2025Q1 FY2026Q2 FY2026
Revenue386401329310180185238265179182174182174184150157152148124164
Cost of revenue244293244194148129138n/an/an/a13213113499.010710710284.478.483.6
Gross profit14210985.311631.356.099.3n/an/an/a42.151.740.184.742.649.449.964.045.880.0
Gross margin37%27%26%37%17%30%42%n/an/an/a24%28%23%46%28%32%33%43%37%49%
R&D18.321.018.317.318.819.532.618.219.419.421.924.128.830.430.830.330.132.829.233.2
SG&A10513811810179.774.075.679.872.272.970.268.898.267.059.159.653.850.548.652.9
Operating income37.8-63.1-72.4-10.7-87.8-55.3-30.67.0-64.4-69.0-71.5-61.714.2-33.1-67.2-60.048.1-38.3-51.0-7.0
Operating margin10%-16%-22%-3%-49%-30%-13%3%-36%-38%-41%-34%8%-18%-45%-38%32%-26%-41%-4%
Interest expensen/an/an/a3.13.0n/a3.43.33.43.57.78.217.414.215.570.311.411.310.911.4
Pre-tax income31.5-65.8-76.7-86.3-126-102-17.0-16.4-78.4-72.5-83.2-10.648.435.0-73.4-16341.4-46.9-61.0-13.4
Tax rate9%n/an/an/an/an/an/an/an/an/an/an/a49%60%n/an/a48%n/an/an/a
Net income28.7-73.8-55.4-102-86.1-85.2-18.3-19.6-84.5-66.5-81.8-10.324.914.0-67.6-14821.6-31.3-54.8-8.4
Net margin7%-18%-17%-33%-48%-46%-8%-7%-47%-37%-47%-6%14%8%-45%-95%14%-21%-44%-5%
Diluted EPS$0.04-$0.11-$0.08-$0.14-$0.11-$0.11-$0.02-$0.03 basic-$0.11-$0.09 basic-$0.12-$0.01$0.03$0.01-$0.10-$0.19$0.03-$0.04-$0.07-$0.01
Operating cash flow33.4-5.6-19.9-11.5-32.2-31.6-22.6-0.433.1-38.3-35.6-26.4-77.1-44.4-34.6-83.4-34.6-25.9-19.3-43.5
Capital expenditure7.26.75.35.47.66.33.06.04.23.04.47.27.95.43.23.33.12.71.83.0
Free cash flow26.2-12.4-25.1-16.9-39.8-38.0-25.7-6.428.9-41.3-40.0-33.7-85.0-49.8-37.7-86.7-37.8-28.6-21.1-46.5
Buybacksn/an/an/an/an/an/a0.00.00.00.050.00.023.816.50.018.315.313.54.813.0
Shares outstanding681m681m682m772m773m773m773m773m773m697m697m697m682m672m793m794m768m759m755m746m
Filing10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q
Each quarter as filed, linked to its filing.
Read moreMoney is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

Income statement (profit and loss), 17 fiscal years and the trailing twelve months

FY2009FY2010 †FY2011 †FY2012 †FY2013 †FY2014 †FY2015 †FY2016 †FY2017 †FY2018 †FY2019FY2020FY2021FY2022FY2023 †FY2024FY2025TTM
Revenue4.428.528.047.096.591.14481,1179669909021,4351,7751,004863713607588
Cost of revenue2.913.517.227.910.49.41935646206055728941,193716545495401348
Gross profit1.515.010.719.286.181.8254553346386329541582288318219206240
Gross margin34.9%52.6%38.4%40.7%89.2%89.7%56.8%49.5%35.8%38.9%36.5%37.7%32.8%28.7%36.8%30.6%33.9%40.8%
Research and development10.85.911.419.553.983.610211412612611875.376.873.989.6105124125
Selling, general and administrative10.418.119.227.855.357.9172407415358343356469373301304223206
Operating income-22.1-11.1-23.2-37.3-79.6-146-121-96.6-276-171-27457.718.8-226-157-152-117-48.2
Operating margin-501.3%-39.1%-82.9%-79.2%-82.5%-160.0%-26.9%-8.6%-28.6%-17.3%-30.4%4.0%1.1%-22.5%-18.2%-21.3%-19.3%-8.2%
Interest expense1.81.21.0n/an/an/an/an/an/an/an/an/a18.912.113.547.50.045.0
Pre-tax income-24.1-12.0-24.2-37.1-104-171-160-96.8-272-177-30548.7-14.0-392-184-10.4-241-79.8
Income tax-0.0-0.0-19.4-9.61.70.0-114-56.118.9-38.77.117.615.5-63.54.442.8-15.7-7.0
Effective tax raten/an/an/an/an/an/an/an/an/an/an/a36.2%n/an/an/an/an/an/a
Net income-30.1-18.9-1.3-29.0-114-172-52.1-48.4-305-153-31530.6-30.1-328-189-53.2-226-72.9
Net margin-681.6%-66.4%-4.6%-61.7%-118.5%-188.4%-11.6%-4.3%-31.6%-15.5%-34.9%2.1%-1.7%-32.7%-21.9%-7.5%-37.2%-12.4%
Diluted EPS-$0.15 basic-$0.08-$0.01-$0.11-$0.32-$0.41-$0.11-$0.10-$0.55-$0.27-$0.53$0.05-$0.05-$0.46-$0.25-$0.08-$0.30-$0.09
Filing10-K10-K10-K10-K10-K10-K8-K8-K8-K10-K10-K10-K10-K10-K10-K10-K10-K
From each year's 10-K, linked; TTM is the last four quarters.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are. † The year as the company last restated it in a later filing; rest on a figure for the one first filed. EPS is as filed.

Revenue by region FY2023 to FY2025

FY2023FY2024FY2025Share
of the parts, latest year
United States59854643671.9%
CL68.565.062.410.3%
Ireland14148.451.48.5%
Spain23.524.626.74.4%
Mexico20.223.925.54.2%
Other Countries2.23.14.30.7%
Israel9.71.80.50.1%
United StatesCLIrelandSpainMexicoOther CountriesIsrael
863FY2023713FY2024607FY2025

$ million; hover a block for its figure and share

From the company's 10-Ks, in its own words (latest 10-K).
Read moreEach year's figures come from the most recent 10-K that includes that year. A year is shown only where the parts add up to the revenue above. Fiscal years are labelled by the year they end in.

Cash flow and capital returned

FY2009FY2010 †FY2011 †FY2012 †FY2013 †FY2014 †FY2015 †FY2016 †FY2017 †FY2018 †FY2019FY2020FY2021FY2022FY2023 †FY2024FY2025TTM
Operating cash flow-23.5-18.7-18.5-25.4-55.7-90.416432.0-92.1-109-17339.538.3-95.2-28.2-183-179-123
Capital expenditure0.10.82.01.54.04.710.818.546.527.912.733.732.224.616.325.012.310.6
Free cash flow-23.6-19.5-20.5-26.9-59.6-95.115313.5-139-137-1855.86.2-120-44.5-208-191-134
Free cash flow margin-533.7%-68.4%-73.1%-57.2%-61.8%-104.4%34.2%1.2%-14.3%-13.8%-20.5%0.4%0.3%-11.9%-5.2%-29.2%-31.4%-22.8%
Cash from investing-22.6-2.8-14.8-24.830.3-5.7-99.2-20.7-46.7-26.1-13.3-18.335.991.0-18.2352230206
Cash from financing81.9-2.886.96.01847.333.0-35.261.0141175-35.1-10.423.0-11.3184-118-52.7
Depreciation and amortisation0.62.23.810.215.214.942.296.610297.393.885.478.710910598.291.689.7
Share-based compensation4.26.57.05.111.014.826.142.728.321.813.48.913.618.511.411.010.710.8
Buybacksn/an/a7.80.00.0n/an/an/an/an/an/an/an/a0.00.090.247.046.6
Diluted shares, weighted233m255m281mn/an/an/a488m556m559m563m595m641m648m719m752m694m751m755m
Shares outstanding at period endn/a255m255m298mn/an/an/an/an/an/an/an/an/an/an/an/an/a746m
Filing10-K10-K10-K10-K10-K10-K8-K8-K8-K10-K10-K10-K10-K10-K10-K10-K10-K
Cash paid in the year, from the cash flow statement.
Read moreThe dividend per share is as declared. Diluted shares are the weighted average for the year; a falling count is the buybacks net of issuance. TTM sums the last four quarters; the share counts are the latest quarter's.

Balance sheet at year end

FY2009FY2010 †FY2011 †FY2012 †FY2013 †FY2014 †FY2015 †FY2016 †FY2017 †FY2018 †FY2019FY2020FY2021FY2022FY2023 †FY2024FY2025TTM
Funded by
Shareholders' equity31.623.11611798768422,0002,0461,8441,7911,6151,6721,6851,5621,3891,3651,2681,184
Non-controlling interestn/an/an/a-0.5-3.4-6.40.0n/an/an/an/an/an/an/an/an/an/an/a
Redeemable equityn/an/a24.424.40.0n/an/an/an/an/an/an/an/an/an/an/an/an/a
Debtn/an/an/a5.215.815.914.012.713.54.7270251205256242437344349
Operating lease liabilitiesn/an/an/an/an/an/an/an/an/an/a27.729.833.128.054.148.836.834.0
Finance lease liabilitiesn/an/an/an/an/an/an/an/an/an/a4.02.82.97.17.34.13.42.7
Other liabilitiesn/a54.844.281.4503416786707733655393518473314319345280260
Total liabilities and equityn/a77.82292901,3921,2682,8002,7672,5902,4512,3092,4732,4002,1672,0122,2001,9321,829
Owned
Fixed assetsn/a2.65.415.717.016.4132123147145127141n/a82.975.470.173.971.5
Goodwilln/a5.939.880.5226224743705717700672681521596598529484482
Intangible assetsn/a6.876.784.274.562.6638764684614529475322824740617516478
Investmentsn/a5.16.715.630.722.534.741.140.631.220.715.710.728.116.154.614.240.2
Cash and equivalents42.718.071.527.418696.919416991.596.585.572.213515395.9427364301
Receivablesn/a11.912.521.219.820.019422016614413528626012712311890.381.9
Inventoryn/a16.413.322.318.116.639.747.249.342.353.413286.574.165.756.865.861.9
Other assetsn/a11.23.523.08198088246986956786876701,066282297328323314
Total assetsn/a77.82292901,3921,2682,8002,7672,5902,4512,3092,4732,4002,1672,0122,2001,9321,829
Filing10-K10-K10-K10-K10-K10-K8-K8-K8-K10-K10-K10-K10-K10-K10-K10-K10-K
At the fiscal year end; the TTM column is the latest quarter end.
Read moreBoth totals are the company's own. Other liabilities is the filed total less the rows above it: payables, deferred revenue, taxes, borrowings the rows above do not carry and the rest; other assets is the same on the other side. Investments add the current and non-current lines as filed. Debt is the company's own stated total where it files one, otherwise its long-term debt with the current maturities, never parts added together. A row is left blank in a year where the lines shown overlap and the remainder would fall below nil.

Compounded growth

10 years5 years3 yearsTTM
Sales growth, compounded3.1%-15.8%-15.5%-11.5%
Profit growth, compoundedn/an/an/an/a
Return on equity, average-10.3%-11.6%-11.8%-17.8%
Yearly growth, compounded; TTM is the last four quarters against the four before.
Read moreReturn on equity is net income over shareholders' equity at each year end, averaged over the window (the TTM column is the latest year alone); equity is the parent's shareholders' equity as tagged in the 10-K. Arithmetic on filed numbers, nothing forecast.

Questions

What was Opko Health's revenue in fiscal 2025?

Opko Health (OPK) reported revenue of $607 million for fiscal 2025, the year ended 31 December 2025, down 14.9% on the year before.

How much did Opko Health earn in fiscal 2025?

Net loss was $226 million for fiscal 2025, and the diluted loss per share $0.30.

What is Opko Health's market cap?

The market cap of Opko Health was $1.2 billion at the close of 29 October 2026.

How much debt does Opko Health have?

At 30 June 2026 Opko Health carried $349 million of debt and $301 million of cash.

Peers: Pharmaceutical Products

CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Eli Lilly & Co. LLY$1.29 trillion44.5668.5%n/a45.5%1.230.5%
Johnson & Johnson JNJ$662.4 billion41.6919.7%n/a7.8%0.551.9%
AbbVie Inc. ABBV$513.9 billion82.15n/a26.2%10.4%n/a2.3%
Merck & Co., Inc. MRK$361.0 billion117.057.6%n/a4.6%1.292.3%
Novartis AG NVS *$307.3 billion22.5230.3%n/a8.4%0.622.5%
AstraZeneca PLC AZN *$270.6 billion26.6821.0%23.4%8.6%0.571.8%
Abbott Laboratories ABT$180.9 billion33.8410.6%15.8%8.1%0.642.4%
Novo Nordisk A/S NVO *$174.8 billion11.3452.8%41.3%6.4%0.674.5%
Pfizer Inc. PFE$170.7 billion39.415.1%n/a-0.2%0.745.7%
Vertex Pharmaceuticals Inc. VRTX$136.8 billion31.4421.8%38.0%10.2%0.00n/a
Bristol-Myers Squibb Co. BMY$125.5 billion13.6139.5%22.6%4.2%1.834.1%
Sanofi SNY *$105.2 billion12.0910.9%n/a6.2%0.265.1%
All 167 in Pharmaceutical Products
CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Eli Lilly & Co. LLY$1.29 trillion44.5668.5%n/a45.5%1.230.5%
Johnson & Johnson JNJ$662.4 billion41.6919.7%n/a7.8%0.551.9%
AbbVie Inc. ABBV$513.9 billion82.15n/a26.2%10.4%n/a2.3%
Merck & Co., Inc. MRK$361.0 billion117.057.6%n/a4.6%1.292.3%
Novartis AG NVS *$307.3 billion22.5230.3%n/a8.4%0.622.5%
AstraZeneca PLC AZN *$270.6 billion26.6821.0%23.4%8.6%0.571.8%
Amgen Inc. AMGN$249.1 billion28.6474.8%30.0%9.1%4.902.1%
Gilead Sciences, Inc. GILD$205.5 billionn/a-27.4%-8.2%5.5%2.221.9%
Abbott Laboratories ABT$180.9 billion33.8410.6%15.8%8.1%0.642.4%
Novo Nordisk A/S NVO *$174.8 billion11.3452.8%41.3%6.4%0.674.5%
Pfizer Inc. PFE$170.7 billion39.415.1%n/a-0.2%0.745.7%
Vertex Pharmaceuticals Inc. VRTX$136.8 billion31.4421.8%38.0%10.2%0.00n/a
Bristol-Myers Squibb Co. BMY$125.5 billion13.6139.5%22.6%4.2%1.834.1%
Sanofi SNY *$105.2 billion12.0910.9%n/a6.2%0.265.1%
GSK plc GSK *$97.7 billion13.1134.9%24.3%4.1%1.083.5%
Moderna, Inc. MRNA$88.9 billionn/a-46.6%-149.0%-27.6%0.09n/a
Regeneron Pharmaceuticals, Inc. REGN$86.6 billion20.2013.7%24.7%9.3%0.060.4%
Takeda Pharmaceutical Company Limited TAK *$63.3 billionn/a-2.1%0.1%-1.7%0.663.3%
argenx SE ARGX *$55.5 billion45.8617.6%n/a89.9%0.00n/a
Teva Pharmaceutical Industries Ltd. TEVA$48.3 billion69.139.1%9.3%4.1%2.14n/a
IDEXX Laboratories Inc. IDXX$45.4 billion40.5070.7%32.0%12.8%0.60n/a
Biogen Inc. BIIB$36.9 billion106.761.8%4.3%2.3%0.41n/a
Royalty Pharma plc RPRX$36.7 billion35.278.3%59.6%10.0%0.921.4%
Genmab A/S GMAB *$36.3 billion36.7416.5%28.6%19.2%0.90n/a
Zoetis Inc. ZTS$32.6 billion12.9883.1%n/a1.5%2.872.6%
Roivant Sciences Ltd. ROIV$27.1 billionn/a-6.3%-7,914.8%-67.6%0.00n/a
United Therapeutics Corp. UTHR$25.3 billion21.2320.5%44.4%2.5%0.00n/a
Insmed Inc. INSM$24.5 billionn/a-83.4%-37.1%240.0%0.76n/a
Alnylam Pharmaceuticals, Inc. ALNY$23.3 billion9.0375.6%19.5%56.2%0.28n/a
BioNTech SE BNTX *$22.4 billionn/a-5.9%-49.0%4.3%0.01n/a
Viatris Inc. VTRS$22.1 billionn/a-2.9%-0.6%4.4%0.942.5%
Exelixis, Inc. EXEL$16.2 billion19.8448.3%40.2%9.1%0.00n/a
Halozyme Therapeutics, Inc. HALO$15.0 billion39.14288.1%35.9%41.2%14.95n/a
Neurocrine Biosciences Inc. NBIX$14.9 billion21.4719.1%23.6%34.4%0.00n/a
BridgeBio Pharma, Inc. BBIO$13.9 billionn/an/a-38.5%167.3%n/an/a
Jazz Pharmaceuticals plc JAZZ$13.5 billion14.3319.6%19.5%12.6%0.91n/a
Dr. Reddy’s Laboratories Limited RDY *$11.8 billion26.0511.4%15.0%3.2%0.210.6%
Elanco Animal Health Inc. ELAN$11.6 billionn/a-3.0%n/a12.0%0.56n/a
Bio-Techne Corp. TECH$11.3 billion63.238.6%20.7%-0.4%0.090.4%
Biomarin Pharmaceutical Inc. BMRN$11.1 billion155.191.2%4.4%11.2%0.66n/a
Twist Bioscience Corp. TWST$10.9 billionn/a-30.7%-33.6%19.2%0.03n/a
Repligen Corp. RGEN$10.6 billion258.472.0%8.2%16.5%0.26n/a
Kymera Therapeutics, Inc. KYMR$10.5 billionn/a-21.6%-396.0%133.8%0.00n/a
Madrigal Pharmaceuticals, Inc. MDGL$10.0 billionn/a-62.1%-25.1%149.0%0.65n/a
Krystal Biotech, Inc. KRYS$9.6 billion40.6417.8%44.9%22.6%0.00n/a
Protagonist Therapeutics, Inc. PTGX$9.3 billion140.039.9%20.7%34.8%0.00n/a
Corcept Therapeutics Inc. CORT$9.3 billion204.677.8%0.8%16.0%0.00n/a
ImmunityBio, Inc. IBRX$9.2 billionn/an/a-151.9%192.9%n/an/a
TG Therapeutics, Inc. TGTX$8.9 billion21.2073.1%17.1%76.1%1.23n/a
Cytokinetics Inc. CYTK$8.8 billionn/an/a-1,046.1%-21.1%n/an/a
Arrowhead Pharmaceuticals, Inc. ARWR$8.5 billionn/a-68.7%-33.8%16.8%1.86n/a
Kiniksa Pharmaceuticals International, plc KNSA$8.3 billion75.1015.4%13.8%58.2%0.00n/a
Alkermes plc. ALKS$7.6 billion119.423.7%7.0%10.8%0.84n/a
Axsome Therapeutics, Inc. AXSM$7.5 billionn/a-230.1%-24.0%56.9%2.26n/a
Ionis Pharmaceuticals Inc. IONS$7.4 billionn/a-128.5%-68.0%-7.4%3.01n/a
Amneal Pharmaceuticals, Inc. AMRX$6.8 billion43.55476.5%14.6%9.3%80.86n/a
Lantheus Holdings, Inc. LNTH$6.5 billion24.2321.0%19.4%2.3%0.43n/a
Rhythm Pharmaceuticals, Inc. RYTM$6.4 billionn/a-199.4%-83.6%53.5%1.03n/a
Ligand Pharmaceuticals Inc. LGND$6.3 billion33.9420.4%32.6%54.9%1.16n/a
CG Oncology, Inc. CGON$5.6 billionn/a-21.8%-4,056.2%1,030.3%0.00n/a
Mirum Pharmaceuticals, Inc. MIRM$5.6 billionn/an/a-134.9%44.0%n/an/a
PTC Therapeutics, Inc. PTCT$5.4 billionn/an/a12.8%-35.1%n/an/a
Scholar Rock Holding Corp. SRRK$5.4 billionn/an/an/an/a0.77n/a
Crispr Therapeutics AG CRSP$5.2 billionn/a-25.8%-3,990.0%-64.8%0.34n/a
Gossamer Bio, Inc. GOSS$5.2 billionn/an/a-311.7%32.4%n/an/a
Travere Therapeutics, Inc. TVTX$4.8 billionn/a-177.2%-6.8%77.1%24.58n/a
Adaptive Biotechnologies Corp. ADPT$4.5 billionn/a-44.7%-12.2%50.1%2.34n/a
Iovance Biotherapeutics, Inc. IOVA$4.3 billionn/a-39.3%-92.7%34.5%0.00n/a
Relay Therapeutics, Inc. RLAY$4.3 billionn/a-32.1%-2,999.7%23.9%0.00n/a
Indivior Pharmaceuticals, Inc. INDV$4.2 billionn/an/a40.6%16.4%n/an/a
Arcutis Biotherapeutics, Inc. ARQT$4.0 billion152.2912.9%7.4%76.1%0.49n/a
Liquidia Corp. LQDA$4.0 billion32.8771.0%37.4%2,233.6%n/an/a
AbCellera Biologics Inc. ABCL$4.0 billionn/a-18.4%-340.2%101.3%0.00n/a
Tango Therapeutics, Inc. TNGX$3.8 billionn/a-12.1%-253.4%121.5%0.00n/a
Organon & Co. OGN$3.6 billion17.9620.8%n/a-2.5%8.500.6%
Xenon Pharmaceuticals Inc. XENE$3.6 billionn/a-32.9%n/an/a0.00n/a
Acadia Pharmaceuticals Inc. ACAD$3.6 billion9.3529.1%7.6%11.8%0.00n/a
Viking Therapeutics, Inc. VKTX$3.4 billionn/a-106.6%n/an/a0.43n/a
Bausch Health Companies Inc. BHC$3.3 billionn/an/a11.2%10.8%n/an/a
DBV Technologies S.A. DBVT$3.2 billionn/a-139.5%-5,420.1%-31.5%0.00n/a
Tarsus Pharmaceuticals, Inc. TARS$3.2 billionn/a-13.4%-8.0%105.2%0.210.0%
Ideaya Biosciences, Inc. IDYA$3.2 billionn/an/an/an/a0.00n/a
Denali Therapeutics Inc. DNLI$3.1 billionn/an/an/an/a0.00n/a
Beam Therapeutics Inc. BEAM$3.0 billionn/a-8.0%-242.3%158.9%0.09n/a
Nurix Therapeutics, Inc. NRIX$3.0 billion11.7330.5%41.3%738.8%0.000.0%
Viridian Therapeutics, Inc. VRDN$2.8 billionn/a-58.4%-569.7%23,220.3%0.54n/a
Silence Therapeutics plc SLN$2.8 billionn/a-155.8%-11,106.8%-97.7%0.00n/a
Neogen Corp. NEOG$2.7 billionn/a-2.7%-0.8%-0.3%0.37n/a
Adma Biologics, Inc. ADMA$2.6 billion16.7941.4%43.8%8.0%0.48n/a
NewAmsterdam Pharma Co. N.V. NAMS$2.4 billionn/a-41.1%-3,432.2%-88.9%0.00n/a
Supernus Pharmaceuticals, Inc. SUPN$2.4 billionn/a-4.1%-5.7%26.9%0.00n/a
Precigen, Inc. PGEN$2.4 billionn/an/an/an/a2.15n/a
Arcus Biosciences, Inc. RCUS$2.4 billionn/a-99.1%-415.4%-55.3%0.22n/a
Celldex Therapeutics, Inc. CLDX$2.3 billionn/a-42.1%-207,534.4%-97.3%0.00n/a
Prestige Consumer Healthcare Inc. PBH$2.3 billion13.669.0%26.3%-1.4%1.05n/a
Aurinia Pharmaceuticals Inc. AUPH$2.3 billion7.5151.1%48.4%19.8%0.00n/a
Recursion Pharmaceuticals, Inc. RXRX$2.3 billionn/a-56.7%-991.7%-15.1%0.02n/a
Harmony Biosciences Holdings, Inc. HRMY$2.2 billion12.5318.1%24.0%24.3%0.15n/a
Agios Pharmaceuticals, Inc. AGIO$2.2 billionn/a-40.1%-466.8%140.6%0.00n/a
Perrigo Co. plc PRGO$2.2 billionn/a-69.0%-37.7%-4.2%1.317.3%
Vericel Corp. VCEL$2.2 billion91.346.5%6.0%23.0%0.00n/a
Biocryst Pharmaceuticals Inc. BCRX$2.2 billionn/an/a-33.3%68.7%n/an/a
Xencor Inc. XNCR$2.2 billionn/a-32.5%-205.8%-28.6%0.21n/a
Immunome Inc. IMNM$2.1 billionn/a-48.4%n/an/a0.00n/a
Septerna, Inc. SEPN$2.1 billionn/a-6.3%-44.0%13,520.1%0.00n/a
Zymeworks Inc. ZYME$2.1 billionn/a-186.6%-419.0%-69.8%0.00n/a
Trulieve Cannabis Corp. TRLV$2.0 billionn/a-61.8%-24.3%-3.9%0.38n/a
Sarepta Therapeutics, Inc. SRPT$2.0 billionn/a-8.9%-7.3%-20.4%0.55n/a
Vir Biotechnology, Inc. VIR$2.0 billionn/a-25.6%-92.4%1,495.9%0.00n/a
Schrodinger, Inc. SDGR$1.9 billionn/a-16.5%-59.2%8.9%0.00n/a
Xeris Biopharma Holdings, Inc. XERS$1.9 billionn/an/a10.9%36.3%n/an/a
Intellia Therapeutics, Inc. NTLA$1.9 billionn/a-55.0%-711.7%12.6%0.00n/a
Zenas BioPharma, Inc. ZBIO$1.8 billionn/an/an/an/a1.20n/a
Maze Therapeutics, Inc. MAZE$1.8 billionn/an/an/an/a0.09n/a
uniQure N.V. QURE$1.8 billionn/a-77.8%-1,071.5%30.2%0.15n/a
Novavax Inc. NVAX$1.7 billionn/an/a-56.6%-61.6%n/an/a
Nuvation Bio Inc. NUVB$1.7 billionn/a-59.0%-81.0%1,083.6%0.98n/a
Ultragenyx Pharmaceutical Inc. RARE$1.7 billionn/an/a-73.6%17.5%n/an/a
ANI Pharmaceuticals Inc. ANIP$1.6 billion15.5718.1%15.4%30.9%1.02n/a
Stoke Therapeutics, Inc. STOK$1.6 billionn/a-60.2%-809.7%-86.2%0.00n/a
UroGen Pharma Ltd. URGN$1.6 billionn/an/a-35.3%100.3%n/an/a
Immunocore Holdings plc IMCR$1.6 billionn/a-4.3%-5.2%21.0%0.940.0%
Ocular Therapeutix, Inc. OCUL$1.6 billionn/a-58.0%-603.0%-8.1%0.14n/a
Phibro Animal Health Corp. PAHC$1.6 billion16.0025.9%12.8%17.1%1.911.2%
Innoviva, Inc. INVA$1.5 billion5.2029.0%36.9%18.8%0.21n/a
Eton Pharmaceuticals, Inc. ETON$1.5 billion137.6927.2%15.4%81.5%0.60n/a
Pacira BioSciences, Inc. PCRX$1.4 billion103.972.2%2.7%5.7%0.54n/a
Taysha Gene Therapies, Inc. TSHA$1.4 billionn/a-38.6%-2,792.3%-32.3%0.13n/a
Omeros Corp. OMER$1.4 billionn/an/an/an/an/an/a
Syndax Pharmaceuticals Inc. SNDX$1.3 billionn/a-1,462.1%-77.1%222.3%16.17n/a
Cronos Group Inc. CRON$1.2 billion16.826.5%-1.4%37.5%0.00n/a
Opko Health, Inc. OPK$1.2 billionn/a-6.2%-8.2%-11.5%0.29n/a
Rapport Therapeutics, Inc. RAPP$1.2 billionn/an/an/an/a0.00n/a
Amphastar Pharmaceuticals, Inc. AMPH$1.1 billion15.9310.2%15.7%1.0%0.79n/a
Harrow, Inc. HROW$1.1 billionn/a-244.9%-1.0%21.1%19.24n/a
Janux Therapeutics, Inc. JANX$1.1 billionn/a-11.1%-598.1%5,367.0%0.00n/a
Mannkind Corp. MNKD$1.1 billionn/an/a2.3%30.5%n/an/a
Inhibrx Biosciences, Inc. INBX$1.1 billionn/an/an/an/an/an/a
Rigel Pharmaceuticals Inc. RIGL$961 million3.1575.7%31.5%3.3%0.09n/a
Kura Oncology, Inc. KURA$940 millionn/a-612.8%-411.9%n/a0.20n/a
QuidelOrtho Corp. QDEL$940 millionn/a-59.1%-30.8%-2.5%1.63n/a
Monte Rosa Therapeutics, Inc. GLUE$928 millionn/a-33.1%-633.0%-83.9%0.00n/a
Cryoport, Inc. CYRX$926 millionn/an/an/an/a0.38n/a
MeiraGTx Holdings plc MGTX$914 million13.6736.6%46.3%948.3%0.46n/a
Verastem, Inc. VSTM$874 millionn/an/an/an/a1.48n/a
Arbutus Biopharma Corp. ABUS$846 million5.4259.2%82.0%1,078.8%0.00n/a
Nektar Therapeutics NKTR$799 millionn/a-17.4%-257.8%-27.2%0.00n/a
Collegium Pharmaceutical, Inc. COLL$780 million19.3715.4%19.5%14.3%3.50n/a
Ardelyx, Inc. ARDX$772 millionn/a-37.4%-7.9%16.8%1.69n/a
Wave Life Sciences, Inc. WVE$715 millionn/a-52.4%-320.9%n/a0.00n/a
Design Therapeutics, Inc. DSGN$694 millionn/a-35.1%n/an/a0.00n/a
Gyre Therapeutics, Inc. GYRE$676 millionn/a-29.7%-14.0%16.8%0.00n/a
Lexicon Pharmaceuticals, Inc. LXRX$666 millionn/a-35.0%-131.4%-29.0%0.29n/a
Myriad Genetics Inc. MYGN$637 millionn/a-37.1%-12.2%-3.2%0.40n/a
Zevra Therapeutics, Inc. ZVRA$614 million11.0226.8%60.5%119.4%0.00n/a
Geron Corp. GERN$608 millionn/an/an/an/a0.55n/a
Ironwood Pharmaceuticals Inc. IRWD$598 million4.70n/a60.1%26.2%n/an/a
CorMedix Inc. CRMD$593 million3.5740.6%47.0%n/a0.00n/a
Aclaris Therapeutics, Inc. ACRS$559 millionn/a-60.8%-1,050.2%-51.0%0.00n/a
Puma Biotechnology, Inc. PBYI$538 million20.2619.3%13.2%-2.9%0.00n/a
Arvinas, Inc. ARVN$516 million79.051.7%-5.7%-15.0%0.00n/a
Phathom Pharmaceuticals, Inc. PHAT$507 millionn/an/a-9.3%86.8%n/an/a
Aquestive Therapeutics, Inc. AQST$505 millionn/an/a-97.5%22.6%n/an/a
CytomX Therapeutics, Inc. CTMX$496 millionn/a-26.4%-476.2%-87.0%0.00n/a
Evolus, Inc. EOLS$495 millionn/an/a-5.9%13.9%n/an/a
Monopar Therapeutics MNPR$483 millionn/an/an/an/a0.00n/a
Crescent Biopharma, Inc. CBIO$391 millionn/an/an/an/a0.00n/a
120 companies share its SEC industry code (Pharmaceutical Preparations); the rest are the names nearest in size in its wider industry, Pharmaceutical Products, one of the Fama-French 48 industries, a published grouping of SEC industry codes.
Read moreBy market capitalisation; a click on a heading sorts by it, largest first, and a second click turns it round. Each figure is the same arithmetic as the ratio box above, on each company's own filings and latest close; a name marked * is a foreign company that files once a year, on its latest fiscal year.

Filings

FilingPeriodFiledWhere
10-Q/A30 June 202628 August 2026EDGAR
10-Q/A31 March 202628 August 2026EDGAR
10-Q30 June 202627 July 2026EDGAR
10-Q31 March 202628 April 2026EDGAR
10-K31 December 202526 February 2026EDGAR
10-Q30 September 202529 October 2025EDGAR
10-Q30 June 202531 July 2025EDGAR
10-Q31 March 20251 May 2025EDGAR
10-K/A31 December 202421 March 2025EDGAR
10-K31 December 20243 March 2025EDGAR