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Ultragenyx Pharmaceutical Inc. (RARE)

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Ultragenyx Pharmaceutical Inc. (RARE) reported revenue of $214 million for Q2 FY2026, the quarter ended 30 June 2026, up 28.1% on the same quarter a year earlier. Net income was -$92 million, and diluted earnings per share $-0.90. The figures are the company's own, from the 10-Q it filed with the SEC on 5 August 2026.

Revenue$214 millionup 28.1%
Net income-$92 million
Diluted EPS$-0.90
QuarterQ2 FY2026ended 30 June 2026

Ultragenyx Pharmaceutical (RARE) in brief

Ultragenyx Pharmaceutical (RARE) reported revenue of $673 million for fiscal 2025, the year ended 31 December 2025, up 20.1% on the year before.
Read moreNet loss was $575 million and the diluted loss per share $5.83. Revenue was $560 million in fiscal 2024, $434 million in fiscal 2023, $363 million in fiscal 2022 and $351 million in fiscal 2021. Net income in the same years was a loss of $569 million, a loss of $607 million, a loss of $707 million and a loss of $454 million. Over the twelve months to 30 June 2026, Ultragenyx Pharmaceutical reported revenue of $717 million and net loss of $586 million. Revenue grew 19.9% a year, compounded, over the five years to fiscal 2025. Ultragenyx Pharmaceutical had 99 million shares outstanding at the latest filed count. At 30 June 2026 it carried $0 million of debt and $125 million of cash. At the close of 27 October 2026 the market cap of Ultragenyx Pharmaceutical was $1.7 billion.

Ratios

From the filings

ROEn/a
ROCEn/a
Operating margin-73.6%
Net margin-81.7%
FCF marginn/a
Interest covern/a
Debt to equityn/a
Cash conversionn/a
Share count, last 12 months2.3%
Sales CAGR, 3 years22.8%
Profit CAGR, 3 yearsn/a
EPS, TTM-$5.84

At the close of 27 October 2026

Price$16.76
Market cap$1.7 billion
Stock P/En/a
Price to bookn/a
EV / EBITDAn/a
Dividend yieldn/a
Market cap / sales2.30
52-week high$36.54
52-week low$12.88
Price, 1 year-52.5%
Price CAGR, 3 years-20.1%
Price CAGR, 5 years-27.7%
Worked from the filed figures; hover a name for the formula.
Read moreThe priced ones use the latest price, the last regular-hours trade on IEX. Ultragenyx Pharmaceutical Inc.'s balance sheet shows no borrowings, so debt here is nil; lease liabilities are a separate line. Nothing here is a valuation or a view.
RAREgreeksoup.ai
Daily prices to 27 October 2026, adjusted for splits; from 28 September 2026 each day's price is the last regular-hours trade on IEX.
Read moreData provided for free by IEX. By accessing or using IEX Historical Data, you agree to the IEX Historical Data Terms of Use. Day by day for the last three years; before that one point a week, carrying the week's last close and its average daily volume, so a volume bar means the same thing across the whole series; the bars sit under the price on their own scale, on the right. The moving averages need consecutive days and are drawn from the daily part. P/E is the close over the trailing four quarters' EPS as filed at each filing date, on the current share count; the dashed line is the median over the range shown. Sales and margin are quarterly revenue and the operating margin from the tables above. EV/EBITDA, price to book and market cap to sales use the latest filed balance sheet and share count at each date. Before the quarters on file begin, P/E, price to book and market cap to sales stand on each annual report from the day it was filed. Drawn in your browser; the range and overlay you pick are remembered here only.

The public record on RARE

Dividendsno dividend in its filings for fiscal 2012 onward
Filings31 in twelve months: 22 current reports (8-K), about 14 other events; 5 results of operations; 3 material agreement; 1 officer or director change; 1 shareholder vote
Planned insider sales16 Form 144 notices in twelve months, $1.5 million; latest 15 September 2026
Options tapeput/call 0.29 by open interest at the 27 October 2026 close; the straddle prices a 10.1% move to 30 October 2026
13F holders311 funds reported a position for the quarter to 30 June 2026; largest BlackRock, Inc.
Insider trading28 sales and 0 purchases on Form 4 in twelve months
Congress1 House trade disclosed in six months
Short interest20.1 million shares short, 5.18 days to cover at 15 October 2026
Documentsthe 10-K, the 10-Qs, the proxy and 5 earnings press releases, each linked

Quarterly results, the last 20 quarters

Q3 FY2021Q4 FY2021 *Q1 FY2022Q2 FY2022Q3 FY2022Q4 FY2022 *Q1 FY2023Q2 FY2023Q3 FY2023Q4 FY2023 *Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024 *Q1 FY2025 †Q2 FY2025 †Q3 FY2025Q4 FY2025 *Q1 FY2026Q2 FY2026
Revenue81.683.479.989.390.710310010898.1127109147139165139167160207136214
R&D113123143155237171166165157161178162170188166165216203187167
SG&A53.959.467.368.169.872.876.681.474.976.878.280.680.482.587.087.086.687.988.088.0
Operating income-89.8-103-137-142-225-146-154-148-145-122-165-116-132-122-143-108-171-113-169-75.0
Operating margin-110%-123%-171%-158%-248%-141%-153%-137%-148%-96%-152%-79%-95%-74%-103%-65%-107%-55%-124%-35%
Pre-tax income-72.8-122-152-158-239-153-163-159-159-127-170-131-133-133-150-114-180-128-184-91.0
Net income-73.0-122-152-158-245-152-164-160-160-123-171-132-134-133-151-115-180-129-185-92.0
Net margin-89%-147%-191%-177%-270%-147%-163%-148%-163%-97%-157%-90%-96%-81%-109%-69%-113%-62%-136%-43%
Diluted EPS-$1.08-$1.78-$2.19-$2.26-$3.50-$2.16-$2.33-$2.25-$2.23-$1.52-$2.03-$1.52-$1.40-$1.39-$1.57-$1.17-$1.81-$1.29-$1.84-$0.90
Operating cash flow-59.6-54.3-118-77.3-95.3-90.3-157-116-118-83.9-191-77.0-67.0-79.5-166-108-91.4-99.8-197-97.0
Capital expenditure20.616.032.230.926.027.025.013.93.71.63.22.01.60.71.02.51.3n/a1.01.0
Free cash flow-80.2-70.4-150-108-121-117-182-130-122-85.5-194-79.0-68.6-80.2-167-111-92.7n/a-198-98.0
Shares outstanding68m69m70m70m70m70m71m71m72m82m83m92m92m92m94m96m96m97m98m99m
Filing10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q
Each quarter as filed, linked to its filing.
Read more* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS, and its diluted share count where shown, are from the company's results press release for that quarter, checked against the company's filed figures or a second data source. A quarter marked † is shown as the company last restated it in a later filing, so it compares with the quarters around it on one basis; rest on a figure for the one first filed. EPS is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

Income statement (profit and loss), 10 fiscal years and the trailing twelve months

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023 †FY2024 †FY2025TTM
Revenue0.12.651.5104271351363434560673717
Cost of revenuen/a0.01.1n/an/an/an/an/an/an/an/a
Gross profitn/a2.650.3n/an/an/an/an/an/an/an/a
Gross marginn/a100.0%97.8%n/an/an/an/an/an/an/an/a
Research and development183232294357412497706648698750773
Selling, general and administrative64.999.9128162183220278310322349351
Operating income-248-329-371-424-330-382-649-569-536-535-528
Operating margin-186471.4%-12593.5%-721.2%-409.0%-121.8%-108.6%-178.6%-131.1%-95.7%-79.5%-73.6%
Pre-tax income-246-318-197-399-185-453-702-608-568-571-582
Income tax0.0-16.20.53.31.21.05.7-2.02.04.0n/a
Net income-246-302-198-403-187-454-707-607-569-575-586
Net margin-184867.7%-11567.3%-383.7%-388.3%-68.8%-129.2%-194.7%-139.7%-101.6%-85.4%-81.7%
Diluted EPS-$6.21-$7.12-$3.97-$7.12-$3.07-$6.70-$10.12-$8.25-$6.29-$5.83-$5.84
Filing10-K10-K10-K10-K10-K10-K10-K10-K10-K10-K
From each year's 10-K, linked; TTM is the last four quarters.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are. † The year as the company last restated it in a later filing; rest on a figure for the one first filed. EPS is as filed.

Revenue by product or service FY2023 to FY2025

FY2023FY2024FY2025Share
of the parts, latest year
Product sales18028536954.8%
Royalty18327530445.2%
Collaboration and license7100n/a
Product salesRoyaltyCollaboration and license
434FY2023560FY2024673FY2025

$ million; hover a block for its figure and share

From the company's 10-Ks, in its own words (latest 10-K).
Read moreEach year's figures come from the most recent 10-K that includes that year. A year is shown only where the parts add up to the revenue above. Fiscal years are labelled by the year they end in.

Revenue by region FY2023 to FY2025

FY2023FY2024FY2025Share
of the parts, latest year
North America30734037756.0%
Latin America7713117025.3%
Europe, Middle East, and Africa488010816.0%
Asia-Pacific29182.7%
North AmericaLatin AmericaEurope, Middle East, and AfricaAsia-Pacific
434FY2023560FY2024673FY2025

$ million; hover a block for its figure and share

From the company's 10-Ks, in its own words (latest 10-K).
Read moreEach year's figures come from the most recent 10-K that includes that year. A year is shown only where the parts add up to the revenue above. Fiscal years are labelled by the year they end in.

Cash flow and capital returned

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023 †FY2024 †FY2025TTM
Operating cash flow-161-254-291-345-132-339-380-475-414-466-485
Capital expenditure10.22.84.124.843.973.111644.07.06.0n/a
Free cash flow-171-257-295-370-176-412-497-519-421-472n/a
Free cash flow margin-128694.0%-9825.3%-572.2%-357.0%-65.0%-117.2%-136.7%-119.5%-75.2%-70.1%n/a
Cash from investing91.155.5-33.3-13.0-179-195-292168-18.023639.9
Cash from financing139136337679600119501388399478n/a
Depreciation and amortisation3.45.819.58.512.313.218.226.036.035.033.4
Share-based compensation48.368.080.182.085.7105130135158153109
Diluted shares, weightedn/an/an/an/a61m68m70m74m91m99m102m
Shares outstanding at period end41m44m51m58m67m69m70m82m92m97m99m
Filing10-K10-K10-K10-K10-K10-K10-K10-K10-K10-K
Cash paid in the year, from the cash flow statement.
Read moreThe dividend per share is as declared. Diluted shares are the weighted average for the year; a falling count is the buybacks net of issuance. TTM sums the last four quarters; the share counts are the latest quarter's.

Balance sheet at year end

FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023 †FY2024 †FY2025TTM
Funded by
Shareholders' equity4743836096541,154923352275255-80.0-291
Redeemable equityn/an/an/an/an/an/an/a0.07.07.07.0
Debtn/an/an/an/a0.00.00.00.00.00.00.0
Operating lease liabilitiesn/an/an/a29.838.530.519.830.630.024.0n/a
Finance lease liabilitiesn/an/an/an/a0.70.40.0n/an/an/an/a
Other liabilities66.71071114525665691,1731,1851,2111,5811,548
Total liabilities and equity5414917201,1351,7601,5221,5451,4911,5031,5321,264
Owned
Fixed assets17.121.820.044.373.5141260291266244235
Goodwilln/a44.444.444.444.444.444.444.444.044.044.0
Intangible assetsn/a142129129131131160166178176172
Investments337144346327499692764564571316311
Cash and equivalents161100113434714308133214174421125
Receivablesn/a5.212.732.823.128.440.473.4122158200
Inventoryn/a0.87.111.513.016.226.834.045.052.059.0
Other assets25.532.646.4113262162117105103121118
Total assets5414917201,1351,7601,5221,5451,4911,5031,5321,264
Filing10-K10-K10-K10-K10-K10-K10-K10-K10-K10-K
At the fiscal year end; the TTM column is the latest quarter end.
Read moreBoth totals are the company's own. Other liabilities is the filed total less the rows above it: payables, deferred revenue, taxes, borrowings the rows above do not carry and the rest; other assets is the same on the other side. Investments add the current and non-current lines as filed. Debt is the company's own stated total where it files one, otherwise its long-term debt with the current maturities, never parts added together. A row is left blank in a year where the lines shown overlap and the remainder would fall below nil.

Compounded growth

10 years5 years3 yearsTTM
Sales growth, compoundedn/a19.9%22.8%17.5%
Profit growth, compoundedn/an/an/an/a
Return on equity, average-103.8%-173.3%-221.6%n/a
Yearly growth, compounded; TTM is the last four quarters against the four before.
Read moreReturn on equity is net income over shareholders' equity at each year end, averaged over the window (the TTM column is the latest year alone); equity is the parent's shareholders' equity as tagged in the 10-K. Arithmetic on filed numbers, nothing forecast.

Questions

What was Ultragenyx Pharmaceutical's revenue in fiscal 2025?

Ultragenyx Pharmaceutical (RARE) reported revenue of $673 million for fiscal 2025, the year ended 31 December 2025, up 20.1% on the year before.

How much did Ultragenyx Pharmaceutical earn in fiscal 2025?

Net loss was $575 million for fiscal 2025, and the diluted loss per share $5.83.

What is Ultragenyx Pharmaceutical's market cap?

The market cap of Ultragenyx Pharmaceutical was $1.7 billion at the close of 27 October 2026.

How much debt does Ultragenyx Pharmaceutical have?

At 30 June 2026 Ultragenyx Pharmaceutical carried $0 million of debt and $125 million of cash.

Peers: Pharmaceutical Products

CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Eli Lilly & Co. LLY$1.21 trillion43.0278.8%n/a49.6%1.620.5%
Johnson & Johnson JNJ$646.9 billion40.7219.7%n/a7.8%0.552.0%
AbbVie Inc. ABBV$506.2 billion80.92n/a26.2%10.4%n/a2.4%
Merck & Co., Inc. MRK$349.9 billion113.467.6%n/a4.6%1.292.4%
Novartis AG NVS *$299.2 billion21.9330.3%n/a8.4%0.622.6%
AstraZeneca PLC AZN *$263.7 billion26.0021.0%23.4%8.6%0.571.9%
Abbott Laboratories ABT$178.5 billion33.3810.6%15.8%8.1%0.642.4%
Novo Nordisk A/S NVO *$172.7 billion11.2052.8%41.3%6.4%0.674.5%
Pfizer Inc. PFE$169.8 billion39.205.1%n/a-0.2%0.745.8%
Vertex Pharmaceuticals Inc. VRTX$132.0 billion30.3321.8%38.0%10.2%0.00n/a
Bristol-Myers Squibb Co. BMY$125.8 billion13.5641.6%24.2%3.1%1.934.1%
GSK plc GSK *$102.3 billion13.7334.9%24.3%4.1%1.083.3%
All 126 in Pharmaceutical Products
CompanyMarket capP/EROEOp. marginSales growth
TTM
Debt to equityDiv. yield
Eli Lilly & Co. LLY$1.21 trillion43.0278.8%n/a49.6%1.620.5%
Johnson & Johnson JNJ$646.9 billion40.7219.7%n/a7.8%0.552.0%
AbbVie Inc. ABBV$506.2 billion80.92n/a26.2%10.4%n/a2.4%
Merck & Co., Inc. MRK$349.9 billion113.467.6%n/a4.6%1.292.4%
Novartis AG NVS *$299.2 billion21.9330.3%n/a8.4%0.622.6%
AstraZeneca PLC AZN *$263.7 billion26.0021.0%23.4%8.6%0.571.9%
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Gilead Sciences, Inc. GILD$197.4 billionn/a-27.4%-8.2%5.5%2.222.0%
Abbott Laboratories ABT$178.5 billion33.3810.6%15.8%8.1%0.642.4%
Novo Nordisk A/S NVO *$172.7 billion11.2052.8%41.3%6.4%0.674.5%
Pfizer Inc. PFE$169.8 billion39.205.1%n/a-0.2%0.745.8%
Vertex Pharmaceuticals Inc. VRTX$132.0 billion30.3321.8%38.0%10.2%0.00n/a
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GSK plc GSK *$102.3 billion13.7334.9%24.3%4.1%1.083.3%
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Acadia Pharmaceuticals Inc. ACAD$3.5 billion9.0829.1%7.6%11.8%0.00n/a
Ideaya Biosciences, Inc. IDYA$3.2 billionn/an/an/an/a0.00n/a
Denali Therapeutics Inc. DNLI$3.1 billionn/an/an/an/a0.00n/a
Tarsus Pharmaceuticals, Inc. TARS$3.1 billionn/a-13.4%-8.0%105.2%0.210.0%
DBV Technologies S.A. DBVT$3.0 billionn/a-109.7%-3,543.8%29.2%0.00n/a
Nurix Therapeutics, Inc. NRIX$2.9 billion11.5730.5%41.3%738.8%0.000.0%
Viking Therapeutics, Inc. VKTX$2.9 billionn/a-131.0%n/an/a0.00n/a
Silence Therapeutics plc SLN$2.8 billionn/a-155.8%-11,106.8%-97.7%0.00n/a
Viridian Therapeutics, Inc.\DE VRDN$2.7 billionn/a-58.4%-569.7%23,220.3%0.54n/a
Neogen Corp. NEOG$2.7 billionn/a-2.7%-0.8%-0.3%0.37n/a
Beam Therapeutics Inc. BEAM$2.6 billionn/a-8.0%-242.3%158.9%0.09n/a
Adma Biologics, Inc. ADMA$2.5 billion15.9841.4%43.8%8.0%0.48n/a
NewAmsterdam Pharma Co. N.V. NAMS$2.4 billionn/a-41.1%-3,432.2%-88.9%0.00n/a
Supernus Pharmaceuticals, Inc. SUPN$2.4 billionn/a-10.7%-15.7%24.9%0.00n/a
Celldex Therapeutics, Inc. CLDX$2.4 billionn/a-42.1%-207,534.4%-97.3%0.00n/a
Bausch Health Companies Inc. BHC$2.4 billionn/an/a8.1%10.1%n/a20.3%
Arcus Biosciences, Inc. RCUS$2.3 billionn/a-99.1%-415.4%-55.3%0.22n/a
Aurinia Pharmaceuticals Inc. AUPH$2.3 billion7.5451.1%48.4%19.8%0.00n/a
Agios Pharmaceuticals, Inc. AGIO$2.3 billionn/a-40.1%-466.8%140.6%0.00n/a
Prestige Consumer Healthcare Inc. PBH$2.2 billion13.289.0%26.3%-1.4%1.05n/a
Xencor Inc. XNCR$2.2 billionn/a-32.5%-205.8%-28.6%0.21n/a
Perrigo Co. plc PRGO$2.2 billionn/a-69.0%-37.7%-4.2%1.317.2%
Vericel Corp. VCEL$2.2 billion92.136.5%6.0%23.0%0.00n/a
Harmony Biosciences Holdings, Inc. HRMY$2.2 billion12.3218.1%24.0%24.3%0.15n/a
Precigen, Inc. PGEN$2.2 billionn/an/an/an/a2.15n/a
Recursion Pharmaceuticals, Inc. RXRX$2.2 billionn/a-56.7%-991.7%-15.1%0.02n/a
Immunome Inc. IMNM$2.1 billionn/a-48.4%n/an/a0.00n/a
Biocryst Pharmaceuticals Inc. BCRX$2.1 billionn/an/a-33.3%68.7%n/an/a
Zymeworks Inc. ZYME$2.1 billionn/a-186.6%-419.0%-69.8%0.00n/a
Trulieve Cannabis Corp. TRLV$2.1 billionn/a-61.8%-24.3%-3.9%0.38n/a
Septerna, Inc. SEPN$2.0 billionn/a-6.3%-44.0%13,520.1%0.00n/a
Sarepta Therapeutics, Inc. SRPT$2.0 billionn/a-8.9%-7.3%-20.4%0.55n/a
Vir Biotechnology, Inc. VIR$2.0 billionn/a-25.6%-92.4%1,495.9%0.00n/a
Xeris Biopharma Holdings, Inc. XERS$1.8 billionn/an/a10.9%36.3%n/an/a
Maze Therapeutics, Inc. MAZE$1.8 billionn/an/an/an/a0.09n/a
Zenas BioPharma, Inc. ZBIO$1.7 billionn/an/an/an/a1.20n/a
Intellia Therapeutics, Inc. NTLA$1.7 billionn/a-55.0%-711.7%12.6%0.00n/a
Schrodinger, Inc. SDGR$1.7 billionn/a-16.5%-59.2%8.9%0.00n/a
UroGen Pharma Ltd. URGN$1.7 billionn/an/a-35.3%100.3%n/an/a
Ultragenyx Pharmaceutical Inc. RARE$1.7 billionn/an/a-73.6%17.5%n/an/a
Novavax Inc. NVAX$1.7 billionn/an/a-56.6%-61.6%n/an/a
Immunocore Holdings plc IMCR$1.6 billionn/a-4.3%-5.2%21.0%0.940.0%
Stoke Therapeutics, Inc. STOK$1.6 billionn/a-60.2%-809.7%-86.2%0.00n/a
ANI Pharmaceuticals Inc. ANIP$1.6 billion15.1318.1%15.4%30.9%1.02n/a
Nuvation Bio Inc. NUVB$1.6 billionn/a-59.0%-81.0%1,083.6%0.98n/a
Phibro Animal Health Corp. PAHC$1.6 billion15.7825.9%12.8%17.1%1.911.3%
Innoviva, Inc. INVA$1.5 billion5.1129.0%36.9%18.8%0.210.0%
Pacira BioSciences, Inc. PCRX$1.4 billion104.002.2%2.7%5.7%0.54n/a
Amphastar Pharmaceuticals, Inc. AMPH$1.1 billion15.1310.2%15.7%1.0%0.79n/a
QuidelOrtho Corp. QDEL$928 millionn/a-59.1%-30.8%-2.5%1.63n/a
Collegium Pharmaceutical, Inc. COLL$748 million18.5615.4%19.5%14.3%3.50n/a
85 companies share its SEC industry code (Pharmaceutical Preparations); the rest are the names nearest in size in its wider industry, Pharmaceutical Products, one of the Fama-French 48 industries, a published grouping of SEC industry codes.
Read moreBy market capitalisation; a click on a heading sorts by it, largest first, and a second click turns it round. Each figure is the same arithmetic as the ratio box above, on each company's own filings and latest close; a name marked * is a foreign company that files once a year, on its latest fiscal year.

Filings

FilingPeriodFiledWhere
10-Q30 June 20265 August 2026EDGAR
10-Q31 March 20266 May 2026EDGAR
10-K31 December 202518 February 2026EDGAR
10-Q30 September 20255 November 2025EDGAR
10-Q30 June 20256 August 2025EDGAR
10-Q31 March 20257 May 2025EDGAR
10-K31 December 202419 February 2025EDGAR
10-Q30 September 20246 November 2024EDGAR
10-Q30 June 20242 August 2024EDGAR
10-Q31 March 20243 May 2024EDGAR