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Ionis Pharmaceuticals Inc. planned insider sales

In the last twelve months insiders at Ionis Pharmaceuticals Inc. filed 62 Form 144 notices of planned sales, 1.9 million shares worth $147.6 million at the time of filing, from 20 sellers. The latest, filed 16 October 2026: Devers Shannon L. (officer), 1,357 shares worth $59,708, planned for around 16 October 2026 through Morgan Stanley Smith Barney.

FiledSellerRelationshipSharesValuePlanned saleSold, per Form 4BrokerHow acquiredFiling
16 October 2026Devers Shannon L.Officer1,357$59,70816 October 20261,357 shares from 16 October 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
7 July 2026Kordasiewicz Holly B.Officer1,287$108,4947 July 2026362 shares from 7 July 2026Stifel Nicolaus & Company IncRestricted StockForm 144
7 July 2026Diaz Allene M.Director10,111$863,6377 July 202610,111 shares from 7 July 2026Stifel Nicolaus & Company IncStock Option ExerciseForm 144
7 July 2026Bennett C FrankOfficer67,386$5.7 million7 July 202620,536 shares from 7 July 2026Stifel Nicolaus & Company IncOwned Shares; Stock Option ExerciseForm 144
1 July 2026Klein Joseph IiiDirector11,518$910,4171 July 202611,518 shares from 1 July 2026Stifel Nicolaus & Company IncStock Option ExerciseForm 144
26 June 2026O'Neil Patrick R.Officer3,069$245,52026 June 20263,069 shares from 26 June 2026Stifel Nicolaus & Company IncRestricted StockForm 144
26 June 2026Baroldi MarianaMember of immediate family of any of the foregoing5,635$451,69926 June 2026No matching Form 4 saleStifel Nicolaus & Company IncStock Option ExerciseForm 144
26 June 2026Schneider EugeneOfficer47,884$3.9 million26 June 202626,000 shares from 26 June 2026Stifel Nicolaus & Company IncStock Option ExerciseForm 144
25 June 2026Swayze EricOfficer10,602$839,28725 June 202610,602 shares from 25 June 2026Stifel Nicolaus & Company IncRestricted StockForm 144
15 June 2026Berthelsen Spencer RDirector8,000$587,92015 June 20268,000 shares from 15 June 2026Fidelity Brokerage Services LLCStock Option ExerciseForm 144
12 June 2026Kordasiewicz Holly B.Officer60,846$4.5 million12 June 202660,846 shares from 12 June 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
1 June 2026Berthelsen Spencer RDirector8,000$605,3601 June 20268,000 shares from 1 June 2026Fidelity Brokerage Services LLCOptions Granted - 07/01/2016Form 144
13 May 2026Monia Brett POfficer100,000$7.8 million13 May 202690,173 shares from 13 May 2026Stifel Nicolaus & Company IncStock OptionsForm 144
4 May 2026Loscalzo JosephDirector54,321$4.3 million4 May 202677,289 shares from 4 May 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
28 April 2026Baroldi JosephOfficer1,626$116,72728 April 20267,261 shares from 28 April 2026Stifel Nicolaus & Company IncRestricted StockForm 144
16 April 2026Birchler BrianOfficer973$73,36216 April 2026973 shares from 16 April 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 April 2026Jenne KyleOfficer4,902$369,60016 April 20264,902 shares from 16 April 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 April 2026Baroldi JosephOfficer5,619$423,66016 April 20265,619 shares from 16 April 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
31 March 2026Diaz Allene M.Director68,800$5.5 million3 March 2026No matching Form 4 saleStifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
19 March 2026Schneider EugeneOfficer5,812$412,48619 March 20265,812 shares from 19 March 2026Stifel Nicolaus & Company IncPerformance Stock UnitsForm 144
16 March 2026Hougen Elizabeth LOfficer225,200$16.3 million16 March 2026225,220 shares from 16 March 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
10 March 2026Jenne KyleDirector58,253$4.4 million10 March 202637,277 shares from 10 March 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
9 March 2026O'Neil Patrick R.Officer13,217$994,6129 March 202610,148 shares from 9 March 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
3 March 2026Baroldi JosephOfficer4,096$325,0593 March 20266,659 shares from 3 March 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
3 March 2026Baroldi MarianaOfficer8,198$655,8403 March 2026No matching Form 4 saleStifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
3 March 2026Loscalzo JosephDirector24,000$1.9 million3 March 20261,032 shares from 3 March 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
3 March 2026Devers Shannon L.Officer39,014$3.1 million3 March 202626,299 shares from 3 March 2026Stifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
3 March 2026Klein Joseph IiiDirector65,345$5.0 million3 March 202653,764 shares from 3 March 2026Stifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
13 February 2026Swayze EricOfficer15,642$1.3 million13 February 202615,642 shares from 13 February 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
11 February 2026Parshall B LynneDirector10,000$827,40011 February 202610,000 shares from 11 February 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
6 February 2026Monia Brett POfficer290,203$24.8 million6 February 2026190,203 shares from 6 February 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
2 February 2026Bennett C FrankOfficer85,089$7.1 million2 February 2026170,178 shares from 2 February 2026Stifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
30 January 2026Baroldi JosephOfficer5,296$439,69430 January 20265,296 shares from 30 January 2026Morgan Stanley Smith BarneyPSU granted under 2011 Equity Incentive PlanForm 144
30 January 2026Bennett C FrankOfficer5,885$487,89830 January 20265,885 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026Birchler BrianOfficer6,179$512,27230 January 20266,179 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026O'Neil Patrick R.Officer6,179$512,90630 January 20266,179 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026Swayze EricOfficer6,179$512,90630 January 20266,179 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026Schneider EugeneOfficer6,179$512,90630 January 20266,179 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026Hougen Elizabeth LOfficer6,988$580,04930 January 20266,988 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
30 January 2026Monia Brett POfficer, Director62,970$5.2 million30 January 202662,970 shares from 30 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
22 January 2026Devers Shannon L.Officer3,977$323,49022 January 20263,977 shares from 22 January 2026Stifel Nicolaus & Company IncRestricted Stock UnitsForm 144
21 January 2026Baroldi MarianaMember of immediate family of any of the foregoing1,171$93,68016 January 2026No matching Form 4 saleMorgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Jenne KyleOfficer1,823$138,96416 January 20251,823 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Kordasiewicz Holly B.Officer4,141$315,48516 January 20254,141 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Baroldi JosephOfficer6,999$559,92016 January 20268,056 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Devers Shannon L.Officer8,353$636,62616 January 20268,353 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Birchler BrianOfficer8,480$646,37616 January 20268,480 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Bennett C FrankOfficer8,977$684,26416 January 20268,977 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026O'Neil Patrick R.Officer9,191$700,60316 January 20269,191 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Schneider EugeneOfficer9,302$709,07216 January 20269,302 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Swayze EricOfficer9,884$753,50116 January 20269,933 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Hougen Elizabeth LOfficer12,922$985,10916 January 202612,922 shares from 16 January 2026Morgan Stanley Smith BarneyPSUs granted under 2011 Equity Incentive PlanForm 144
16 January 2026Monia Brett POfficer, Director44,034$3.4 million16 January 202644,034 shares from 16 January 2026Morgan Stanley Smith BarneyRSUs granted under 2011 Equity Incentive PlanForm 144
7 January 2026Devers Shannon L.Officer9,390$795,1177 January 202644,199 shares from 7 January 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
2 January 2026Swayze EricOfficer23,463$1.6 million2 January 202623,463 shares from 2 January 2026Stifel Nicolaus & Company IncOption ExerciseForm 144
1 December 2025Joseph WenderDirector14,479$1.2 million1 December 202528,000 shares from 1 December 2025Goldman Sachs & Co. LLCRestricted Stock Units; Acquired upon option exerciseForm 144
25 November 2025Klein Joseph IiiDirector12,000$960,00025 November 202512,000 shares from 25 November 2025UBS Financial Services, Inc.Exercise of Stock OptionForm 144
25 November 2025Devers Shannon L.Officer42,322$3.4 million25 November 202516,777 shares from 25 November 2025Stifel Nicolaus & Company IncOption ExerciseForm 144
19 November 2025Joan E. HermanDirector44,000$3.3 million19 November 202544,000 shares from 19 November 2025Goldman Sachs & Co. LLCStock OptionsForm 144
31 October 2025Loscalzo JosephOfficer16,000$1.2 million31 October 202516,000 shares from 31 October 2025Stifel Nicolaus & Company IncOption ExerciseForm 144
31 October 2025Geary Richard SOfficer126,168$9.5 million31 October 2025125,568 shares from 31 October 2025Stifel Nicolaus & Company IncOption Exercise; Restricted Stock UnitsForm 144
30 October 2025Joseph WenderDirector33,600$2.5 million30 October 202528,000 shares from 30 October 2025Goldman Sachs & Co. LLCRestricted Stock Units; Acquired upon option exerciseForm 144
A Form 144 is the notice an insider files with the SEC before selling restricted or control shares over the Rule 144 thresholds; it says what may be sold, not what was.
Read moreValue is the filer's own aggregate market value. Sold, per Form 4: the same seller's open-market sales on Form 4 from the notice's date to 90 days after, added up, as they appear on the insiders page; a holder who files no Form 4, such as some large holders, never shows one. What is a Form 144?