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Ionis Pharmaceuticals Inc. insider trading

In twelve months insiders at Ionis Pharmaceuticals bought $1.1M and sold $134M on the open market; 96 of the 124 sales were under plans set months before.

Bought on the open market$1.1M2 purchases
Sold on the open market$134M124 sales
Sales set in advance96 of 124under Rule 10b5-1 plans
Pay taken in stockNone
New to this? How to read this page
  1. Insiders are the people who run the company: officers, directors and owners of 10% or more. They must report a trade on Form 4 within two business days.
  2. A purchase on the open market is the strongest sign: the insider spent their own money.
  3. A sale under a trading plan (Rule 10b5-1) says little: its dates were fixed months before. Sales outside a plan say more, but insiders sell for many reasons, such as taxes or a house.
  4. Grants, option exercises and shares held back for tax are left out.
  5. What is a Form 4? · Form 4 codes

What kind of trades

2 purchases worth $1.1M against 124 sales worth $134M; 96 of the sales were under plans set months before.

Purchasebought with their own money
Pay in stock, own choiceowed cash, chose shares
Sale outside a planthe insider picked the day
Sale under a plandates fixed months before
Says littlecompany plans, board pay, cash units
Bought
2 open market
Sold
2896 under a plan

Every Form 4 line of the last twelve months, counted by kind. The grades come from the filing itself: whether the insider paid cash, whether a plan set the date, whether pay was taken in stock by choice.

Insider trades on the share price

last twelve months

82 marks over twelve months, each in its grade: solid for the stronger signs, hollow or grey for the ones that say little.

PurchasePay in stock, own choiceSale outside a planSale under a planSays little

The blue line is the daily close over twelve months. Each mark is one insider's trades on one day, on that day's price, sized by dollar value. Solid marks are the stronger signs; hollow and grey marks say little. Hover or tap a mark for who, how much and why.

Trades worth a closer look

A purchase stands out when two or more of these hold: a senior insider, several insiders buying within 90 days, a fall of 10% or more in the three months before, or over $1 million. A sale outside a plan is judged the same way. These are the Feed's rules.

Who traded

dollars, twelve months

12 insiders traded. The most: Monia Brett P, sale outside a plan $8.5M; sale under a plan $21.8M.

One row per insider, sold to the left and bought to the right, split by grade: the paler part of a bar is the part that says little.

How it compares

every company on the site

Open-market sales, twelve months

Open-market purchases, twelve months

    The bar ranks every company on the site from the lowest on the left to the highest on the right, in three equal thirds; the small figures under it are the values where each third starts, and the black tick is the middle company. The orange dot is this company; the grey ticks are the other companies in its industry (hover or tap for names). A hatched block is companies tied at none.

    Every Form 4 line

    Purchase: bought on the open market with their own moneyTook pay in stock, own choice: owed cash, chose shares instead; a softer signSale: sold on the open market, not under a plan set in advanceSale, trading plan: under a Rule 10b5-1 plan set up months before, so the date was fixed in advanceGrey lines: plan purchases, pay in stock taken by the whole board or under a company plan, and units paid in cash; they say little about the insider's own view
    TradedInsiderRoleTypeSharesPriceValueFiling
    16 October 2026Devers Shannon L.EVP, Chief Human Resources OfcSaleafter a 21% fall over three months · 50% below its one-year high · Form 144 notice 16 October 20261,357$43.54$59,082Form 4
    16 October 2026Swayze Eric, by SonEVP ResearchSaleafter a 21% fall over three months · 50% below its one-year high53$43.54$2,308Form 4
    31 July 2026Hayden Michael R, by SpouseDirectorPurchaseafter a 31% fall over three months · 40% below its one-year high5,000$51.60$258,000Form 4
    30 July 2026Hayden Michael R, by SpouseDirectorPurchaseafter a 29% fall over three months · 38% below its one-year high15,000$53.38$800,700Form 4
    7 July 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 7 July 20265,536$83.58$462,693Form 4
    7 July 2026Bennett C Frank, by TrustEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 7 July 202615,000$85.46$1.3 millionForm 4
    7 July 2026Diaz Allene M.DirectorSaletrading plan set in advance · Form 144 notice 7 July 202610,111$85.42$863,637Form 4
    7 July 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 7 July 2026362$84.30$30,517Form 4
    1 July 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 1 July 202699$79.45$7,866Form 4
    1 July 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 1 July 202611,419$79.04$902,551Form 4
    26 June 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 28 April 20265,635$80.16$451,699Form 4
    26 June 2026O'Neil Patrick R.EVP CLO & General CounselSaletrading plan set in advance · Form 144 notice 26 June 20263,069$80.00$245,520Form 4
    26 June 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSaletrading plan set in advance · Form 144 notice 26 June 202626,000$81.05$2.1 millionForm 4
    26 June 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 13 May 202650,000$80.59$4.0 millionForm 4
    25 June 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 13 May 202621,072$78.49$1.7 millionForm 4
    25 June 2026Swayze EricEVP ResearchSaletrading plan set in advance · Form 144 notice 25 June 202610,602$79.18$839,492Form 4
    24 June 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 13 May 202614,565$78.41$1.1 millionForm 4
    15 June 2026Berthelsen Spencer RDirectorSaletrading plan set in advance · Form 144 notice 15 June 20268,000$73.49$587,920Form 4
    12 June 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 12 June 202641,004$73.09$3.0 millionForm 4
    12 June 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 12 June 202619,842$74.05$1.5 millionForm 4
    1 June 2026Berthelsen Spencer RDirectorSaletrading plan set in advance · Form 144 notice 1 June 20268,000$75.67$605,360Form 4
    14 May 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 13 May 20263,220$78.68$253,347Form 4
    13 May 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 13 May 20261,316$78.01$102,665Form 4
    4 May 2026Loscalzo JosephDirectorSaletrading plan set in advance · Form 144 notice 4 May 202659,508$74.90$4.5 millionForm 4
    4 May 2026Loscalzo JosephDirectorSaletrading plan set in advance · Form 144 notice 4 May 202617,781$75.58$1.3 millionForm 4
    1 May 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 20268,680$73.35$636,704Form 4
    1 May 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 20261,431$74.45$106,534Form 4
    28 April 2026Baroldi JosephEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 28 April 20261,626$71.79$116,727Form 4
    16 April 2026Jenne KyleEVP, Chf GL Pdt Str OfcrSaleafter a 3% fall over three months · 13% below its one-year high · Form 144 notice 16 April 20264,902$75.17$368,488Form 4
    16 April 2026Birchler BrianEVP, Corp and Development OpsSaleafter a 3% fall over three months · 13% below its one-year high · Form 144 notice 16 April 2026973$75.04$73,016Form 4
    16 April 2026Baroldi JosephEVP, Chief Business OfficerSaleafter a 3% fall over three months · 13% below its one-year high · Form 144 notice 16 April 20265,619$74.56$418,953Form 4
    15 April 2026Parshall B LynneDirectorSaletrading plan set in advance · Form 144 notice 11 February 20264,466$76.19$340,265Form 4
    15 April 2026Parshall B LynneDirectorSaletrading plan set in advance · Form 144 notice 11 February 2026534$76.97$41,102Form 4
    2 April 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 3 March 20266,193$74.05$458,613Form 4
    1 April 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 202620,105$75.50$1.5 millionForm 4
    1 April 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 20262,216$75.95$168,314Form 4
    19 March 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSaletrading plan set in advance · Form 144 notice 19 March 20265,812$70.97$412,486Form 4
    17 March 2026Hougen Elizabeth LEVP, Finance & CFOSaletrading plan set in advance · Form 144 notice 16 March 202610,172$73.21$744,662Form 4
    16 March 2026Hougen Elizabeth LEVP, Finance & CFOSaletrading plan set in advance · Form 144 notice 16 March 2026205,608$72.38$14.9 millionForm 4
    16 March 2026Hougen Elizabeth LEVP, Finance & CFOSaletrading plan set in advance · Form 144 notice 16 March 20269,440$72.77$686,902Form 4
    10 March 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 202616,512$75.47$1.2 millionForm 4
    10 March 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 202617,591$76.34$1.3 millionForm 4
    10 March 2026Jenne KyleEVP, Chf GL Pdt Str OfcrSaletrading plan set in advance · Form 144 notice 10 March 202621,191$75.50$1.6 millionForm 4
    10 March 2026Jenne KyleEVP, Chf GL Pdt Str OfcrSaletrading plan set in advance · Form 144 notice 10 March 202616,086$76.30$1.2 millionForm 4
    9 March 2026O'Neil Patrick R.EVP CLO & General CounselSaletrading plan set in advance · Form 144 notice 9 March 202610,148$75.25$763,662Form 4
    9 March 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 20267,382$74.11$547,087Form 4
    9 March 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 2026117,604$75.26$8.9 millionForm 4
    9 March 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 20261,684$75.58$127,282Form 4
    4 March 2026Loscalzo JosephDirectorSaletrading plan set in advance · Form 144 notice 3 March 2026200$80.00$16,000Form 4
    4 March 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 3 March 2026238$80.00$19,040Form 4
    4 March 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 3 March 2026201$80.00$16,080Form 4
    3 March 2026Loscalzo JosephDirectorSaletrading plan set in advance · Form 144 notice 3 March 2026832$80.33$66,833Form 4
    3 March 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 202613,526$79.17$1.1 millionForm 4
    3 March 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 20266,794$80.00$543,486Form 4
    3 March 2026Klein Joseph IiiDirectorSaletrading plan set in advance · Form 144 notice 3 March 20261,012$80.82$81,788Form 4
    3 March 2026Diaz Allene M.DirectorSaletrading plan set in advance39,265$79.11$3.1 millionForm 4
    3 March 2026Diaz Allene M.DirectorSaletrading plan set in advance14,608$79.88$1.2 millionForm 4
    3 March 2026Diaz Allene M.DirectorSaletrading plan set in advance1,005$80.80$81,203Form 4
    3 March 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 3 March 202614,321$79.11$1.1 millionForm 4
    3 March 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 3 March 20265,030$80.00$402,395Form 4
    3 March 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 3 March 2026755$80.84$61,032Form 4
    3 March 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 202671,600$79.10$5.7 millionForm 4
    3 March 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 202612,687$79.88$1.0 millionForm 4
    3 March 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 2026802$80.76$64,771Form 4
    3 March 2026Baroldi JosephEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 3 March 20264,096$79.36$325,059Form 4
    3 March 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 3 March 20262,088$80.41$167,892Form 4
    3 March 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaletrading plan set in advance · Form 144 notice 3 March 202636$81.01$2,916Form 4
    13 February 2026Swayze EricEVP ResearchSaletrading plan set in advance · Form 144 notice 13 February 20269,435$81.56$769,511Form 4
    13 February 2026Swayze EricEVP ResearchSaletrading plan set in advance · Form 144 notice 13 February 20266,207$82.07$509,403Form 4
    11 February 2026Parshall B LynneDirectorSaletrading plan set in advance · Form 144 notice 11 February 20265,000$82.72$413,588Form 4
    6 February 2026Monia Brett PChief Executive OfficerSaletrading plan set in advance · Form 144 notice 6 February 202629,430$85.79$2.5 millionForm 4
    2 February 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 202620,000$82.60$1.7 millionForm 4
    2 February 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 202648,626$83.03$4.0 millionForm 4
    2 February 2026Bennett C FrankEVP, Chief Scientific OfficerSaletrading plan set in advance · Form 144 notice 2 February 202616,463$83.03$1.4 millionForm 4
    30 January 2026Swayze EricEVP ResearchSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20266,179$82.93$512,446Form 4
    30 January 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20266,179$83.45$515,630Form 4
    30 January 2026O'Neil Patrick R.EVP CLO & General CounselSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20266,179$83.53$516,153Form 4
    30 January 2026Monia Brett PChief Executive OfficerSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 202662,970$82.72$5.2 millionForm 4
    30 January 2026Hougen Elizabeth LEVP, Finance & CFOSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20266,988$83.24$581,702Form 4
    30 January 2026Birchler BrianEVP, Corp and Development OpsSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20266,179$83.03$513,048Form 4
    30 January 2026Bennett C FrankEVP, Chief Scientific OfficerSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20265,885$82.95$488,141Form 4
    30 January 2026Baroldi JosephEVP, Chief Business OfficerSaleafter a 11% rise over three months · at its one-year high · Form 144 notice 30 January 20265,296$82.96$439,364Form 4
    22 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 22 January 20263,977$81.34$323,490Form 4
    16 January 2026Swayze EricEVP ResearchSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20269,884$75.34$744,661Form 4
    16 January 2026Swayze Eric, by SonEVP ResearchSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 202649$75.97$3,723Form 4
    16 January 2026Schneider EugeneEVP, Chf Clinical Develop OfcrSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20269,302$75.59$703,138Form 4
    16 January 2026O'Neil Patrick R.EVP CLO & General CounselSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20269,191$75.84$697,045Form 4
    16 January 2026Monia Brett PChief Executive OfficerSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 202644,034$74.82$3.3 millionForm 4
    16 January 2026Kordasiewicz Holly B.EVP, Chief Development OfficerSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20264,141$75.66$313,308Form 4
    16 January 2026Jenne KyleEVP, Chf GL Pdt Str OfcrSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20261,823$75.96$138,475Form 4
    16 January 2026Hougen Elizabeth LEVP, Finance & CFOSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 202612,922$75.22$971,993Form 4
    16 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20268,353$75.95$634,410Form 4
    16 January 2026Birchler BrianEVP, Corp and Development OpsSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20268,480$75.11$636,933Form 4
    16 January 2026Bennett C FrankEVP, Chief Scientific OfficerSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20268,977$75.15$674,622Form 4
    16 January 2026Baroldi JosephEVP, Chief Business OfficerSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20266,907$75.75$523,205Form 4
    16 January 2026Baroldi Joseph, by SpouseEVP, Chief Business OfficerSaleafter a 4% rise over three months · 8% below its one-year high · Form 144 notice 16 January 20261,149$75.78$87,071Form 4
    7 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 7 January 202625,545$85.36$2.2 millionForm 4
    7 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 7 January 20262,101$85.36$179,341Form 4
    7 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 7 January 20263,460$84.62$292,785Form 4
    7 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 7 January 20263,829$84.62$324,010Form 4
    7 January 2026Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 7 January 20269,264$84.62$783,920Form 4
    2 January 2026Swayze EricEVP ResearchSaletrading plan set in advance · Form 144 notice 2 January 20265,125$78.57$402,671Form 4
    2 January 2026Swayze EricEVP ResearchSaletrading plan set in advance · Form 144 notice 2 January 202618,338$79.27$1.5 millionForm 4
    1 December 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 1 December 202520,571$80.67$1.7 millionForm 4
    1 December 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 1 December 20257,429$81.23$603,486Form 4
    25 November 2025Klein Joseph Iii, by TrustDirectorSaletrading plan set in advance · Form 144 notice 25 November 20254,000$80.00$320,000Form 4
    25 November 2025Klein Joseph Iii, by TrustDirectorSaletrading plan set in advance · Form 144 notice 25 November 20254,000$80.00$320,000Form 4
    25 November 2025Klein Joseph Iii, by TrustDirectorSaletrading plan set in advance · Form 144 notice 25 November 20254,000$80.00$320,000Form 4
    25 November 2025Devers Shannon L.EVP, Chief Human Resources OfcSaletrading plan set in advance · Form 144 notice 25 November 202516,777$80.91$1.4 millionForm 4
    19 November 2025Herman Joan EDirectorSaleafter a 73% rise over three months · at its one-year high · Form 144 notice 19 November 202512,000$72.13$865,590Form 4
    19 November 2025Herman Joan EDirectorSaleafter a 73% rise over three months · at its one-year high · Form 144 notice 19 November 202532,000$72.13$2.3 millionForm 4
    6 November 2025Birchler BrianEVP, Corp and Development OpsSaletrading plan set in advance8,000$76.17$609,379Form 4
    6 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 202514,738$76.10$1.1 millionForm 4
    6 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 202518,300$75.42$1.4 millionForm 4
    5 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 2025800$75.01$60,008Form 4
    5 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 2025801$75.01$60,083Form 4
    3 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 2025775$75.05$58,167Form 4
    3 November 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 2025905$75.05$67,924Form 4
    31 October 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 30 October 202511,200$75.16$841,776Form 4
    31 October 2025Loscalzo JosephDirectorSaletrading plan set in advance · Form 144 notice 31 October 202516,000$75.10$1.2 millionForm 4
    31 October 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 202534,585$75.11$2.6 millionForm 4
    31 October 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 202534,664$75.11$2.6 millionForm 4
    31 October 2025Geary Richard SEVP, Chief Development OfficerSaletrading plan set in advance · Form 144 notice 31 October 202520,000$75.11$1.5 millionForm 4
    30 October 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 30 October 20252,484$72.19$179,320Form 4
    30 October 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 30 October 20258,341$73.16$610,228Form 4
    30 October 2025Wender Joseph H, by TrustDirectorSaletrading plan set in advance · Form 144 notice 30 October 20255,975$73.85$441,254Form 4
    A filing with several lines appears once per line.
    Read morePay taken in stock by the insider's own choice has the filing's footnote, word for word, in the note under it; for the others, hold the pointer on the type. An award filed at no price shows n/a.