Zymeworks Inc. 13F holders
202 funds reported a position in Zymeworks Inc. in their 13F for the quarter ended 30 June 2026, together 69.6 million shares worth $1.82 billion. Against the quarter before, 21 opened a position, 60 added, 73 trimmed and 30 sold out; together they sold a net 2.4 million shares. The largest holders: EcoR1 Capital, LLC, Rubric Capital Management LP and BlackRock, Inc.
Funds holding202-10 on Q1 2026
Shares they held69.6Mworth $1.82 billion
Net sold on the quarter2.4M sharesabout $63.2 million at the funds' values
Funds buying to selling81 to 103opened or added, to cut or sold
Opened 21Added 60Held 46Trimmed 73Sold out 30
What each fund did in ZYME against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in ZYME in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
2,671 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 24 reported a position in Zymeworks Inc.: 3 opened one, 9 added, 2 trimmed and 2 sold out, a net 1.1 million shares sold.
| Fund | Change in shares | Shares now | Status | Filing |
|---|---|---|---|---|
| Assenagon Asset Management S.A. | -995,985 | 1,508,069 | trimmed | 13F |
| Y-Intercept (Hong Kong) Ltd | -65,180 | 18,275 | trimmed | 13F |
| Tema Etfs LLC | +7,254 | 112,869 | added | 13F |
| State of Alaska, Department of Revenue | +3,865 | 3,865 | new | 13F |
| Sterling Capital Management LLC | +1,342 | 1,507 | added | 13F |
| North Growth Management Ltd. | +1,000 | 47,000 | added | 13F |
| GF Fund Management Co. Ltd | +139 | 1,724 | added | 13F |
| Nisa Investment Advisors, LLC | +102 | 583 | added | 13F |
| Gamma Investing LLC | +62 | 1,176 | added | 13F |
| Versant Capital Management, Inc | +49 | 94 | added | 13F |
| SJS Investment Consulting Inc. | +46 | 123 | added | 13F |
| Farther Finance Advisors, LLC | +22 | 52 | added | 13F |
| Mather Group, LLC. | +13 | 13 | new | 13F |
| James T. Borello RIA | +2 | 2 | new | 13F |
| Inspire Investing, LLC | -332 | 0 | sold out | 13F |
| PSP Research LLC | -10,000 | 0 | sold out | 13F |
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 4 reported a position in Zymeworks Inc. in a 13F for the quarter ended 30 June 2026. The largest: Citadel Advisors, 914,136 shares worth $23.9 million, 0.0% of its reported book. New this quarter: Two Sigma Investments. In the quarter, 3 funds added or opened a position and 1 trimmed or sold out; together they sold a net 96,123 shares, about $2.5 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Citadel Advisors | 914,136 | $23.9 million | 0.0% | -235,882 | trimmed | 30 June 2026 | 13F |
| FMR LLC | 702,568 | $18.4 million | 0.0% | +35,415 | added | 30 June 2026 | 13F |
| Geode Capital Management | 692,410 | $18.1 million | 0.0% | +32,470 | added | 30 June 2026 | 13F |
| Two Sigma Investments | 71,874 | $1.9 million | 0.0% | +71,874 | new | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| EcoR1 Capital, LLC | 22,970,388 | 33.00% | $600.4 million | 29.77% | no change | 13F |
| Rubric Capital Management LP | 7,000,000 | 10.06% | $183.0 million | 1.68% | no change | 13F |
| BlackRock, Inc. | 4,251,030 | 6.11% | $111.1 million | 0.00% | -302,858 | 13F |
| Perceptive Advisors LLC | 4,182,953 | 6.01% | $109.3 million | 1.70% | +672,875 | 13F |
| BVF Inc. | 3,649,142 | 5.24% | $95.4 million | 2.44% | -85,000 | 13F |
| Assenagon Asset Management S.A. | 2,504,054 | 3.60% | $65.5 million | 0.04% | 13F | |
| Morgan Stanley | 2,231,260 | 3.21% | $58.3 million | 0.00% | -249,308 | 13F |
| BNP Paribas Asset Management Holding S.A. | 1,781,116 | 2.56% | $46.6 million | 0.05% | -126,923 | 13F |
| Vanguard Capital Management LLC | 1,558,998 | 2.24% | $40.8 million | 0.00% | -146,582 | 13F |
| Nextech Invest Ltd. | 1,113,946 | 1.60% | $29.1 million | 1.38% | no change | 13F |
| State Street Corp. | 1,088,216 | 1.56% | $28.4 million | 0.00% | +76,439 | 13F |
| Dimensional Fund Advisors LP | 994,955 | 1.43% | $26.0 million | 0.01% | -144,180 | 13F |
| Citadel Advisors LLC | 914,136 | 1.31% | $23.9 million | 0.01% | -235,882 | 13F |
| Nomura Asset Management International Inc. | 889,802 | 1.28% | $23.3 million | 0.04% | new | 13F |
| FMR LLC | 702,568 | 1.01% | $18.4 million | 0.00% | +35,415 | 13F |
| Geode Capital Management, LLC | 692,410 | 0.99% | $18.1 million | 0.00% | +32,470 | 13F |
| Prosight Management, LP | 674,434 | 0.97% | $17.6 million | 3.04% | +135,385 | 13F |
| Qube Research & Technologies Ltd | 593,590 | 0.85% | $15.5 million | 0.02% | +81,653 | 13F |
| Vanguard Portfolio Management LLC | 510,032 | 0.73% | $13.3 million | 0.00% | +10,157 | 13F |
| Redmile Group, LLC | 491,654 | 0.71% | $12.9 million | 0.86% | no change | 13F |
| Capricorn Fund Managers Ltd | 486,529 | 0.70% | $12.7 million | 1.02% | -520,681 | 13F |
| Goldman Sachs Group Inc. | 470,822 | 0.68% | $12.3 million | 0.00% | -128,664 | 13F |
| Arrowstreet Capital, Limited Partnership | 418,497 | 0.60% | $10.9 million | 0.01% | -325,401 | 13F |
| Deutsche Bank AG | 397,190 | 0.57% | $10.4 million | 0.00% | -524,060 | 13F |
| Hillsdale Investment Management Inc. | 382,922 | 0.55% | $10.0 million | 0.23% | +37,300 | 13F |
| First Trust Advisors LP | 340,363 | 0.49% | $8.9 million | 0.01% | new | 13F |
| Granahan Investment Management, LLC | 336,157 | 0.48% | $8.8 million | 0.31% | +85,384 | 13F |
| Northern Trust Corp. | 321,073 | 0.46% | $8.4 million | 0.00% | +863 | 13F |
| Pictet Asset Management Holding SA | 308,187 | 0.44% | $7.4 million | 0.01% | +298,931 | 13F |
| Picton Mahoney Asset Management | 271,343 | 0.39% | $7.1 million | 0.07% | +14,653 | 13F |
| Silvercrest Asset Management Group LLC | 223,766 | 0.32% | $5.8 million | 0.04% | +60,117 | 13F |
| Bank of America Corp. | 219,071 | 0.31% | $5.7 million | 0.00% | -17,683 | 13F |
| Wells Fargo & Company | 217,199 | 0.31% | $5.7 million | 0.00% | +27,563 | 13F |
| SummitTX Capital, L.P. | 210,802 | 0.30% | $5.5 million | 0.14% | -110,625 | 13F |
| Man Group plc | 210,779 | 0.30% | $5.5 million | 0.01% | +20,889 | 13F |
| Federated Hermes, Inc. | 187,995 | 0.27% | $4.9 million | 0.01% | +5,585 | 13F |
| Raymond James Financial Inc. | 166,416 | 0.24% | $4.4 million | 0.00% | -9,995 | 13F |
| State of Wisconsin Investment Board | 155,579 | 0.22% | $4.1 million | 0.01% | +89,473 | 13F |
| Charles Schwab Investment Management Inc. | 152,416 | 0.22% | $4.0 million | 0.00% | -32,708 | 13F |
| Kennedy Capital Management LLC | 145,386 | 0.21% | $3.8 million | 0.07% | -2,840 | 13F |
| D. E. Shaw & Co., Inc. | 144,807 | 0.21% | $3.8 million | 0.00% | -90,814 | 13F |
| Diadema Partners LP | 142,132 | 0.20% | $3.7 million | 1.40% | no change | 13F |
| Citigroup Inc. | 131,441 | 0.19% | $3.4 million | 0.00% | +17,114 | 13F |
| Bank of New York Mellon Corp | 131,106 | 0.19% | $3.4 million | 0.00% | +7,001 | 13F |
| XTX Topco Ltd | 125,877 | 0.18% | $3.3 million | 0.04% | -18,005 | 13F |
| Nuveen, LLC | 119,389 | 0.17% | $3.1 million | 0.00% | -532,273 | 13F |
| Panagora Asset Management Inc. | 118,603 | 0.17% | $3.1 million | 0.01% | -88,251 | 13F |
| UBS Group AG | 115,095 | 0.17% | $3.0 million | 0.00% | -56,684 | 13F |
| Invesco Ltd. | 112,212 | 0.16% | $2.9 million | 0.00% | -13,418 | 13F |
| AQR Capital Management LLC | 111,282 | 0.16% | $2.9 million | 0.00% | +20,613 | 13F |
The 50 largest of the 202 funds that reported a position in ZYME in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on ZYME
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 52,200 | $1.4 million | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 15 May 2026 | 13G/A | Rubric Capital Management LP and 3 others | 7.0 million | 9.5% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 April 2026 | 13G | Perceptive Advisors LLC and 5 others | 4.0 million | 5.4% | 8 April 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 13 February 2026 | 13G/A | Rubric Capital Management LP and 3 others | 5.8 million | 7.7% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 12 February 2026 | 13G/A | Morgan Stanley and 1 other | 2.5 million | 3.4% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 19 November 2025 | 13D/A | EcoR1 Capital, LLC and 2 others | 23.0 million | 30.7% | 16 November 2025 | Scott Platshon, one of EcoR1's employees, resigned from the Issuer's board of directors as of November 16, 2025. Concurrently with his resignation, Mr. Platshon was appointed as the Issuer's Acting Chief Investment Officer. Oleg Nodelman, t | EDGAR |
| 14 November 2025 | 13G/A | Redmile Group, LLC and 3 others | 3.7 million | 4.9% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 14 November 2025 | 13G/A | Biotechnology Value Fund L P and 19 others | 3.9 million | 5.2% | 30 September 2025 | passive, under 20% (13d-1(c)) | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 21 September 2026 | 17,984 | $26.57 | SEC |
| 18 September 2026 | 1,155 | $27.48 | SEC |
| 27 August 2026 | 56 | $29.31 | SEC |
| 25 August 2026 | 43 | $28.77 | SEC |
| 24 August 2026 | 79 | $28.67 | SEC |
| 19 August 2026 | 6 | $26.07 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.