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Diadema Partners LP

CIK 2026172 · latest 13F filed 14 August 2026 · Read the filing on EDGAR

Diadema Partners LP reported 77 US-listed holdings worth $264.6 million in its 13F for the quarter ended 30 June 2026, filed 14 August 2026. Its largest: United Therapeutics Corp. (10.9%), Revolution Medicines, Inc. (9.9%) and Abivax SA (8.2%). Against the quarter before, it opened 29 positions, added to 21, trimmed 19 and sold out of 38.

Reported holdings$264.6M+9.2% on Q1 2026
Positions77-9 on Q1 2026
The largest ten62.7%of its reported holdings
Latest 13FQ2 2026filed 14 August 2026
Where the money is
OpenedAdded toTrimmed
UTHR10.9%RVMD9.9%ABVX8.2%COGT7.2%BMRN6.8%VKTX6.5%EWTX4.2%KOD3.2%IMCR3.1%FDMT2.9%RCUS2.6%JNJ2.1%63 more29.1%

The 14 largest of its 77 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.

Reported holdings, quarter by quarter
Q4 2024: $88.7 million in 54 positions$88.7MQ4 24Q1 2025: $125.1 million in 43 positions$125MQ1 25Q2 2025: $160.8 million in 46 positions$161MQ2 25Q3 2025: $143.6 million in 59 positions$144MQ3 25Q4 2025: $167.9 million in 73 positions$168MQ4 25Q1 2026: $242.2 million in 86 positions$242MQ1 26Q2 2026: $264.6 million in 77 positions$265MQ2 26

What the fund reported holding at each quarter's end; hover a bar for the number of positions

What its reported holdings returned

Held through each quarter, the holdings it reported returned +56.1% over the 6 quarters to 30 June 2026, against +27.4% for the S&P 500.

Its reported holdingsThe S&P 500
100120140160Q4 24Q1 25Q2 25Q3 25Q4 25Q1 26Q2 26Its holdings +56.1%S&P 500 +27.4%

Not the fund's own return: each 13F's holdings are kept unchanged until the next one, so trades inside a quarter, dividends, cash and fees are left out. A rough guide to how its picks have done over time.

What it did on the quarter

Opened 29Added 21Held 8Trimmed 19Sold out 38
Opened: 29Added: 21Held: 8Trimmed: 19Sold out: 38

Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held

Opened 29

  1. Edgewise Therapeutics Inc. EWTX$11.1 million
  2. 4D Molecular Therapeutics in FDMT$7.6 million
  3. Relay Therapeutics Inc. RLAY$4.3 million
  4. Taysha Gene Therapies Inc. TSHA$3.6 million
  5. Nurix Therapeutics Inc. NRIX$2.9 million
  6. Oruka Therapeutics Inc. ORKA$2.6 million
  7. Vera Therapeutics Inc. VERA$2.5 million
  8. Contineum Therapeutics Inc. CTNM$2.0 million

and 21 more in the table below

Added to 21

  1. United Therapeutics Corp. UTHR+25,686 shares · +94%
  2. Abivax SA ABVX+87,700 shares · +115%
  3. Revolution Medicines, Inc. RVMD+58,346 shares · +72%
  4. Biomarin Pharmaceutical Inc. BMRN+164,617 shares · +111%
  5. Cogent Biosciences Inc. COGT+170,900 shares · +53%
  6. Novo Nordisk A/S NVO+85,423 shares · +586%
  7. Bioage Labs Inc. BIOA+86,334 shares · +144%
  8. Immunocore Hldgs PLC IMCR+61,674 shares · +32%

and 13 more in the table below

Trimmed 19

  1. Johnson & Johnson JNJ-31,771 shares · -59%
  2. Viking Therapeutics Inc. VKTX-83,373 shares · -16%
  3. Monte Rosa Therapeutics Inc. GLUE-108,916 shares · -58%
  4. Harmony Biosciences Holdings, Inc. HRMY-66,000 shares · -71%
  5. Corbus Pharmaceuticals Hldgs CRBP-138,693 shares · -32%
  6. Macrogenics Inc. MGNX-225,597 shares · -38%
  7. Mannkind Corp. MNKD-170,600 shares · -91%
  8. Annexon Inc. ANNX-105,400 shares · -79%

and 11 more in the table below

Sold out of 38

  1. Bridgebio Pharma Inc.$18.6 million last quarter
  2. Jazz Pharmaceuticals plc JAZZ$10.4 million last quarter
  3. Terns Pharmaceuticals Inc. TERN$9.6 million last quarter
  4. Incyte Corp. INCY$7.3 million last quarter
  5. TG Therapeutics, Inc. TGTX$6.9 million last quarter
  6. Bridgebio Pharma Inc. BBIO$6.3 million last quarter
  7. Eli Lilly & Co. LLY$5.5 million last quarter
  8. AbbVie Inc. ABBV$5.2 million last quarter

What it holds

CompanySharesValueOf its bookChange in shares
United Therapeutics Corp. UTHR53.0K$28.7 million10.85%+25.7K
Revolution Medicines, Inc. RVMD139.2K$26.1 million9.86%+58.3K
Abivax SA ABVX163.6K$21.6 million8.16%+87.7K
Cogent Biosciences Inc. COGT493.7K$19.1 million7.22%+170.9K
Biomarin Pharmaceutical Inc. BMRN312.8K$17.9 million6.77%+164.6K
Viking Therapeutics Inc. VKTX441.8K$17.2 million6.51%-83.4K
Edgewise Therapeutics Inc. EWTX272.2K$11.1 million4.18%new
Kodiak Sciences Inc. KOD218.1K$8.5 million3.21%+25.2K
Immunocore Hldgs PLC IMCR254.9K$8.1 million3.06%+61.7K
4D Molecular Therapeutics in FDMT571.1K$7.6 million2.87%new
Arcus Biosciences, Inc. RCUS223.8K$6.9 million2.61%-14.3K
Johnson & Johnson JNJ22.0K$5.6 million2.11%-31.8K
Novo Nordisk A/S NVO100.0K$4.8 million1.82%+85.4K
Corvus Pharmaceuticals Inc. CRVS294.8K$4.4 million1.66%+50.0K
Relay Therapeutics Inc. RLAY230.7K$4.3 million1.63%new
Zymeworks Inc. ZYME142.1K$3.7 million1.40%no change
Bioage Labs Inc. BIOA146.3K$3.6 million1.36%+86.3K
Taysha Gene Therapies Inc. TSHA522.6K$3.6 million1.35%new
Nurix Therapeutics Inc. NRIX121.5K$2.9 million1.11%new
Corbus Pharmaceuticals Hldgs CRBP301.3K$2.8 million1.07%-138.7K
Indivior Pharmaceuticals, Inc. INDV67.5K$2.8 million1.05%-3.9K
Inventiva SA IVA740.8K$2.7 million1.03%+388.4K
Oruka Therapeutics Inc. ORKA27.8K$2.6 million1.00%new
Vaxcyte Inc. PCVX45.1K$2.6 million0.99%+20.0K
Relmada Therapeutics Inc. RLMD361.4K$2.5 million0.95%+160.5K
Vera Therapeutics Inc. VERA57.6K$2.5 million0.93%new
Contineum Therapeutics Inc. CTNM119.7K$2.0 million0.74%new
Bicycle Therapeutics PLC BCYC462.7K$2.0 million0.74%-13.7K
Monte Rosa Therapeutics Inc. GLUE78.4K$1.9 million0.72%-108.9K
Viridian Therapeutics Inc. VRDN100.0K$1.8 million0.69%new
Macrogenics Inc. MGNX374.4K$1.7 million0.65%-225.6K
Proqr Thrapeutics N V PRQR926.0K$1.7 million0.65%+745.9K
Spruce Biosciences Inc. SPRB30.0K$1.6 million0.61%+20.0K
Ardelyx Inc. ARDX303.0K$1.5 million0.58%new
Cue Biopharma Inc. Com CUE48.4K$1.5 million0.58%new
Mineralys Therapeutics Inc. MLYS56.3K$1.5 million0.57%+30.0K
Prothena Corp. PLC PRTA149.5K$1.5 million0.55%new
Voyager Therapeutics Inc. VYGR413.6K$1.4 million0.55%-10.0K
Unicycive Therapeutics Inc. UNCY303.7K$1.4 million0.54%+197.6K
Phathom Pharmaceuticals Inc. PHAT129.9K$1.4 million0.53%+75.3K
Spyre Therapeutics Inc. SYRE15.0K$1.3 million0.50%new
Cybin Inc. HELP200.0K$1.3 million0.50%new
Equillium Inc. EQ400.3K$1.3 million0.48%-33.6K
Xeris Biopharma Holdings Inc. XERS132.7K$1.1 million0.40%no change
Pharvaris N V PHVS29.3K$1.0 million0.38%no change
Harmony Biosciences Holdings, Inc. HRMY26.9K$978,1180.37%-66.0K
Selecta Biosciences, Inc. RNAC87.1K$907,1340.34%new
Rigel Pharmaceuticals Inc. RIGL22.8K$892,5620.34%new
Summit Therapeutics Inc. SMMT60.0K$874,2000.33%new
Precigen Inc. PGEN135.3K$771,1700.29%+80.0K
Definium Therapeutics Inc. DFTX15.5K$726,8150.27%new
Pelthos Therapeutics Inc. PTHS24.8K$700,0850.26%no change
Pepgen Inc. PEPG373.3K$671,9110.25%+222.4K
Enliven Therapeutics Inc. ELVN10.0K$507,5000.19%+9.8K
Connect Biopharma Hldgs Ltd CNTB197.0K$468,8240.18%-3.7K
Larimar Therapeutics Inc. LRMR146.6K$447,2430.17%-20.0K
Cellectar Biosciences Inc. CLRB138.3K$384,5880.15%new
Foghorn Therapeutics Inc. FHTX66.9K$326,5110.12%-13.0K
Aytu Biopharma Inc. AYTU148.5K$319,3740.12%-204.5K
Ocugen Inc. OCGN200.0K$306,0000.12%no change
Urogen Pharma Ltd URGN7.1K$262,6420.10%-16.0K
Amgen Inc. AMGN102.7K$214,6450.08%new
Heron Therapeutics Inc. HRTX458.7K$195,7830.07%new
Talphera Inc. TLPH153.6K$158,1700.06%no change
Annexon Inc. ANNX27.5K$157,1160.06%-105.4K
Monopar Therapeutics Inc. MNPR1.6K$150,9220.06%no change
Lakeland Inds Inc. LAKE14.1K$150,8150.06%new
Upstream Bio Inc. UPB19.1K$132,1240.05%-2.5K
Meiragtx Holdings PLC MGTX8.4K$113,0520.04%new
Jatt II Acquisition Corp. JATT9.0K$102,4790.04%new
Kailera Therapeutics Inc. KLRA3.6K$79,7710.03%new
Mannkind Corp. MNKD16.0K$68,1730.03%-170.6K
Entera Bio Ltd ENTX23.3K$41,1700.02%no change
Ars Pharmaceuticals Inc. SPRY4.9K$38,9290.01%new
Aprea Therapeutics Inc. APRE44.9K$36,0290.01%new
Tvardi Therapeutics Inc. TVRD16.6K$31,5530.01%new
Nextcure Inc. NXTC7.7K$12,3870.00%new
Every US-listed position in the fund's 13F for the quarter ended 30 June 2026, by the value it reported.
Read moreChange is shares against its 13F for the quarter before; the 38 it sold out of are in the box above.

Options it reported

CompanyOptionShares under the optionsValue of those shares
Viking Therapeutics Inc. VKTXCalls1.2M$47.6 million
Abivax SA ABVXCalls349.2K$46.5 million
Bristol-Myers Squibb Co. BMYCalls600.0K$34.6 million
Abivax SA ABVXPuts252.4K$33.6 million
Bristol-Myers Squibb Co. BMYPuts330.6K$19.0 million
Corcept Therapeutics Inc. CORTCalls206.3K$17.9 million
Kymera Therapeutics Inc. KYMRCalls149.7K$17.2 million
Novartis AG NVSPuts100.0K$15.7 million
Uniqure NV QUREPuts299.0K$13.8 million
Viking Therapeutics Inc. VKTXPuts350.5K$13.7 million
Biogen Inc. BIIBCalls60.0K$13.0 million
Capricor Therapeutics Inc. CAPRPuts534.4K$12.9 million
Summit Therapeutics Inc. SMMTCalls860.2K$12.5 million
Eli Lilly & Co. LLYPuts10.0K$12.0 million
Incyte Corp. INCYPuts105.4K$11.9 million
Uniqure NV QURECalls235.4K$10.8 million
BioNTech SE BNTXCalls100.0K$9.3 million
Capricor Therapeutics Inc. CAPRCalls329.3K$7.9 million
Novartis AG NVSCalls50.0K$7.8 million
Replimune Group, Inc. REPLCalls696.3K$7.7 million
Kodiak Sciences Inc. KODCalls196.7K$7.7 million
Moderna, Inc. MRNAPuts100.0K$7.0 million
Hims & Hers Health, Inc. HIMSCalls200.0K$6.9 million
Hims & Hers Health, Inc. HIMSPuts193.7K$6.7 million
Corbus Pharmaceuticals Hldgs CRBPCalls633.8K$5.9 million
Sellas Life Sciences Group I SLSCalls400.0K$5.9 million
Kodiak Sciences Inc. KODPuts146.9K$5.7 million
Alumis Inc. ALMSCalls200.0K$5.6 million
Royalty Pharma PLC RPRXCalls100.0K$5.6 million
Replimune Group, Inc. REPLPuts502.5K$5.6 million
Bioage Labs Inc. BIOACalls200.1K$4.9 million
Biohaven Ltd BHVNCalls317.0K$4.7 million
Tenax Therapeutics Inc. TENXCalls307.0K$4.5 million
TG Therapeutics, Inc. TGTXCalls75.7K$4.2 million
Monte Rosa Therapeutics Inc. GLUECalls170.1K$4.1 million
Arcus Biosciences, Inc. RCUSCalls124.0K$3.8 million
Unicycive Therapeutics Inc. UNCYCalls792.6K$3.7 million
Amgen Inc. AMGNCalls10.0K$3.6 million
Intellia Therapeutics Inc. NTLACalls200.0K$3.4 million
Celldex Therapeutics Inc. CLDXPuts86.0K$3.2 million
Vaxcyte Inc. PCVXCalls53.1K$3.1 million
Summit Therapeutics Inc. SMMTPuts200.0K$2.9 million
Vaxcyte Inc. PCVXPuts48.9K$2.8 million
Novo Nordisk A/S NVOPuts55.9K$2.7 million
Cytokinetics Inc. CYTKPuts30.0K$2.6 million
Vera Therapeutics Inc. VERAPuts50.0K$2.1 million
Celcuity Inc. CELCCalls20.0K$2.1 million
Annexon Inc. ANNXCalls353.2K$2.0 million
Septerna Inc. SEPNPuts59.7K$2.0 million
Corvus Pharmaceuticals Inc. CRVSCalls133.4K$2.0 million
Celldex Therapeutics Inc. CLDXCalls50.9K$1.9 million
Adma Biologics, Inc. ADMACalls200.0K$1.7 million
Eyepoint Pharmaceuticals Inc. EYPTCalls106.3K$1.5 million
Sellas Life Sciences Group I SLSPuts100.0K$1.5 million
Evolus Inc. EOLSCalls200.0K$1.4 million
Cormedix Inc. CRMDPuts167.5K$1.3 million
Editas Medicine, Inc. EDITCalls400.0K$1.3 million
Pyxis Oncology Inc. PYXSCalls388.2K$1.2 million
Aquestive Therapeutics Inc. AQSTCalls214.6K$892,736
Cybin Inc. HELPCalls100.0K$661,000
Voyager Therapeutics Inc. VYGRCalls150.0K$525,000
CG Oncology Inc. CGONCalls7.3K$518,665
Elicio Therapeutics Inc. ELTXCalls112.1K$438,311
Elicio Therapeutics Inc. ELTXPuts100.0K$391,000
Inovio Pharmaceuticals Inc. INOCalls275.2K$302,720
Vistagen Therapeutics Inc. VTGNCalls57.7K$13,040
Atyr Pharma Inc. ATYRPuts12.5K$7,460
Meiragtx Holdings PLC MGTXCalls500$6,755
Jade Biosciences Inc. JBIOPuts1.0K$3,174
Erasca Inc. ERASCalls100$1,832
Cue Biopharma Inc. Com CUECalls6$6

71 option lines. A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost; they are not counted in the holdings above.