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Veracyte, Inc.: Q3 FY2026 earnings call

What management said about Q3 FY2026, from the documents filed with the SEC on 4 November 2026: press release. Guidance figures: 1 lowered, 1 narrowed, 1 new, 1 kept. The quarter’s numbers.

Key takeaways

  • Revenue grew 15% to $151.8M: Total revenue was $151.8M against $131.9M a year earlier. Testing revenue was $146.4M, up 15%, driven by Decipher Prostate and Afirma. Source
  • Prosigna IVD product sales up 40%: Product revenue was $4.6M, up 40%. Management attributed this to adoption of Prosigna IVD after phase III OPTIMA trial results at ASCO. Source
  • Non-GAAP operating expenses up 24%: GAAP operating expenses were $90.5M against $68.3M. Non-GAAP operating expenses were $72.9M, up from $58.6M a year earlier. Source
  • GAAP net income up $12.4M: GAAP net income was $31.5M, a rise of $12.4M. GAAP diluted EPS was $0.38, up $0.14 from a year earlier. Source
  • Adjusted EBITDA up 4%: Adjusted EBITDA was $41.2M, an improvement of 4%. The reconciliation shows 27.2% of revenue, against 30.1% in the third quarter of 2025. Source
  • Quarter operating cash $40.3M: Operating cash generated in the quarter was $40.3M. Cash, equivalents and short-term investments totaled $370.5M at September 30. Source

“We delivered solid third quarter results supported by strong profitability and cash generation,”

Marc Stapley, chief executive officer of Veracyte

Guidance

AreaPeriodFigureAgainst last quarter
Total revenue Source2026$590 million to $593 millionNarrowed, top end cut from $590 million to $596 million
Testing revenue Source2026$571 million to $573 millionLowered from $576 million to $582 million
Adjusted EBITDA margin Source2026greater than 26%Kept
Share repurchases SourceProgram term of 12 monthsup to $100 million of common stockNew

What changed from last quarter

  • Guidance lowered: Total revenue guidance moved to $590 million to $593 million from $590 million to $596 million; the top of the range came down. Source
  • Guidance lowered: Testing revenue guidance moved to $571 million to $573 million from $576 million to $582 million. Source
  • Guidance kept: Adjusted EBITDA margin expectation of greater than 26% continued from the prior release. Source
  • New: Acquired Convergent Genomics, adding a urinary tumor DNA testing platform for bladder cancer care. Source
  • New: Medicare reimbursement secured for Prosigna Breast ROR in eligible early-stage HR+ breast cancer patients. The second quarter release reported only the launch. Source

Revenue and test volume growth

  • Revenue grew 15% to $151.8M: Total revenue was $151.8M against $131.9M a year earlier. Testing revenue was $146.4M, up 15%, driven by Decipher Prostate and Afirma. Source
  • Total test volume rose 15%: Total volume was 52,744 tests, up 15%. Testing volume was 49,498 tests, up 13%. Volume for each test grew 12% year-over-year. Source
  • Testing growth slower than second quarter: Testing revenue grew 15% in the third quarter, against 19% in the second quarter according to the prior release.

Product lines and test counts

  • Decipher Prostate revenue up 12%: Decipher Prostate revenue was $92.3M, up 12%, against 20% growth to $91.9M in the second quarter. Afirma revenue rose 19% to $51.5M. Source
  • Prosigna IVD product sales up 40%: Product revenue was $4.6M, up 40%. Management attributed this to adoption of Prosigna IVD after phase III OPTIMA trial results at ASCO. Source
  • Decipher and Afirma test counts: About 29,900 Decipher Prostate tests and about 19,100 Afirma tests were cited as the volume drivers for the quarter. Source
  • Biopharma revenue little changed: Biopharmaceutical and other revenue was $0.7M against $0.8M a year earlier. The second quarter release tied the earlier decline to Veracyte SAS restructuring. Source

“our differentiated financial profile enables us to continue investing in the business to drive long-term growth.”

Marc Stapley, chief executive officer of Veracyte

Margins, costs and earnings

  • Gross margin rose to 71%: Total gross margin was 71%, against 69% a year earlier. Non-GAAP gross margin was 74%, against 73%. Source
  • Non-GAAP operating expenses up 24%: GAAP operating expenses were $90.5M against $68.3M. Non-GAAP operating expenses were $72.9M, up from $58.6M a year earlier. Source
  • GAAP net income up $12.4M: GAAP net income was $31.5M, a rise of $12.4M. GAAP diluted EPS was $0.38, up $0.14 from a year earlier. Source
  • Non-GAAP EPS flat at $0.51: Non-GAAP diluted EPS was $0.51, the same as in the third quarter of 2025. Source
  • Adjusted EBITDA up 4%: Adjusted EBITDA was $41.2M, an improvement of 4%. The reconciliation shows 27.2% of revenue, against 30.1% in the third quarter of 2025. Source
  • Legal costs adjusted out of results: Legal proceedings expenses of $3.2M were the main item excluded from third-quarter non-GAAP operating expenses. Source

Cash flow and liquidity

  • Quarter operating cash $40.3M: Operating cash generated in the quarter was $40.3M. Cash, equivalents and short-term investments totaled $370.5M at September 30. Source
  • Nine-month operating cash up $37.6M: Operating cash flow for the first nine months of 2026 was $121.3M, up $37.6M from the same period in 2025. Source
  • Cash balance lower than June: Cash, equivalents and short-term investments were $485.2M at June 30, 2026. The nine-month cash flow statement shows $153.2M paid for business acquisitions.
  • Buyback funded from available cash: Management said the repurchase program would be funded from available cash and cash equivalents. Source

Evidence, reach and portfolio

  • Decipher Prostate evidence expanded: New predictive evidence supports Decipher Prostate use in treatment intensification decisions for intermediate-risk and very high-risk prostate cancer. Source
  • Over 1 million patients served: Cumulative patients served with Veracyte tests passed 1 million, which the company described as a key milestone. Source
  • Urology portfolio widened by acquisition: The Convergent Genomics acquisition adds a urinary tumor DNA test for bladder cancer care to the urology portfolio. Source

Management's view of the quarter

  • Results and cash generation: Chief executive Marc Stapley summarized the quarter as supported by profitability and cash generation. Source
  • Continued investment in growth: The company said its financial profile enables continued investment in the business for long-term growth. Source
  • Confidence in long-term prospects: Management said it remains confident in the long-term prospects of its business. Source

Coming up, as management said on 4 November 2026

  • Evidence-based catalysts expected: Management expects catalysts to support growth in core franchises while advancing breast and bladder strategies. No dates were given. Source

Figures management reported

FigureReported
Patient volumes Sourcemore than 1 million patients served to date
Test volume Source52,744 tests, up 15%

Risks management discussed

  • Demand: Management noted limited near-term revenue from recently launched tests, a factor in the testing guidance range. Source

Earlier plans management reported on

  • Missed: Management said Decipher Prostate volume was below its expectations, while Afirma outperformed. Source
  • Not stated: Management said it continues to expect the margin. The release gives no status against the target. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.