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Veracyte, Inc.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 30 July 2026: press release. Guidance figures: 3 raised. The quarter’s numbers.

Key takeaways

  • Testing revenue grew 19 percent: Testing revenue increased 19% to $145.7 million from $122.3 million in Q2 2025, driven by Decipher Prostate and Afirma Thyroid tests. Source
  • Decipher revenue reached $91.9 million: Decipher grew 20% to $91.9 million, the largest revenue component demonstrating strong prostate cancer diagnostics adoption. Source
  • Afirma revenue increased to $51.2 million: Afirma grew 18% to $51.2 million, reflecting continued adoption of thyroid cancer genomic classifier. Source
  • GAAP net income reached $25.5 million: GAAP net income $25.5 million, or 17.0% of revenue, improved $26.5 million from Q2 2025 loss. Source
  • Adjusted EBITDA reached $44.0 million: Adjusted EBITDA of $44.0 million, representing 29.2% of revenue, improved 23% from Q2 2025 quarter. Source
  • Gross margin improved to 72 percent: Gross margin expanded 300 basis points to 72% from 69% in Q2 2025, reflecting operational efficiency and scale. Source
  • Prosigna Breast Test launched in market: Launched Prosigna Breast Test in U.S. for early-stage HR+ breast cancer patients, meaningfully expanding ability to serve cancer care continuum. Source
  • TrueMRD Monitoring Test now available: Launched TrueMRD Monitoring Test for muscle-invasive bladder cancer patients, expanding platform into new disease indication. Source
  • Medicare coverage secured for TrueMRD: Secured Medicare coverage for TrueMRD platform, representing first Medicare coverage decision for whole-genome sequencing-based monitoring test. Source
  • Operating cash flow reached $81 million: Net cash from operations in first six months 2026 reached $81.0 million, an improvement of $42.1 million versus prior-year period. Source
  • Total revenue guidance raised to $590-596M: Total revenue guidance raised to $590-596 million representing 14-15% growth, up from $582-592 million guidance. Source
  • Testing revenue guidance increased to $576-582M: Testing revenue guidance raised to $576-582 million representing 17-18% growth, up from $570-580 million guidance. Source

Guidance

AreaPeriodFigureAgainst last quarter
Total revenue Source2026 full year$590 million to $596 millionRaised from $582 million to $592 million
Testing revenue Source2026 full year$576 million to $582 millionRaised from $570 million to $580 million
Adjusted EBITDA margin Source2026 full yeargreater than 26 percentRaised from approximately 25 percent

What changed from last quarter

  • Guidance raised: Total revenue guidance raised to $590-596 million from $582-592 million, reflecting strong execution and momentum across business. Source
  • Guidance raised: Testing revenue guidance raised to $576-582 million from $570-580 million as both core and newly launched tests perform well. Source
  • Guidance raised: Adjusted EBITDA margin guidance increased to >26% from ~25%, reflecting stronger operating leverage and execution. Source
  • New: Prosigna Breast Test launched in U.S. for early-stage hormone-receptor positive breast cancer patients, meaningfully expanding addressable market. Source
  • New: TrueMRD Monitoring Test launched for muscle-invasive bladder cancer patients, bringing whole-genome sequencing platform to new indication. Source
  • New: Medicare coverage secured for TrueMRD platform, representing first Medicare coverage for whole-genome sequencing-based TrueMRD monitoring test. Source

Testing Revenue and Product Growth

  • Testing revenue grew 19 percent: Testing revenue increased 19% to $145.7 million from $122.3 million in Q2 2025, driven by Decipher Prostate and Afirma Thyroid tests. Source
  • Decipher revenue reached $91.9 million: Decipher grew 20% to $91.9 million, the largest revenue component demonstrating strong prostate cancer diagnostics adoption. Source
  • Afirma revenue increased to $51.2 million: Afirma grew 18% to $51.2 million, reflecting continued adoption of thyroid cancer genomic classifier. Source
  • Total revenue reached $150.3 million: Total revenue increased 15% to $150.3 million from $130.2 million in prior-year quarter. Source

Volume Growth Across Portfolio

  • Testing volume grew 14 percent: Testing volume increased 14% to 48,389 tests from prior year, reflecting strong patient demand for diagnostics. Source
  • Decipher volume reached approximately 29,700 tests: Decipher testing volume grew 17% to approximately 29,700 tests, indicating accelerating adoption in prostate cancer. Source
  • Afirma volume reached approximately 18,600 tests: Afirma testing volume grew 10% to approximately 18,600 tests, reflecting continued thyroid cancer screening volume. Source

Profitability and Earnings Growth

  • GAAP net income reached $25.5 million: GAAP net income $25.5 million, or 17.0% of revenue, improved $26.5 million from Q2 2025 loss. Source
  • Adjusted EBITDA reached $44.0 million: Adjusted EBITDA of $44.0 million, representing 29.2% of revenue, improved 23% from Q2 2025 quarter. Source
  • Non-GAAP diluted EPS increased to $0.54: Non-GAAP diluted EPS increased $0.10 to $0.54. GAAP diluted EPS improved $0.32 to $0.31. Source

Margin Expansion and Cost Performance

  • Gross margin improved to 72 percent: Gross margin expanded 300 basis points to 72% from 69% in Q2 2025, reflecting operational efficiency and scale. Source
  • Non-GAAP gross margin reached 75 percent: Non-GAAP gross margin improved to 75% from 72% in prior quarter, demonstrating strong unit economics. Source
  • Operating expenses decreased from prior year: GAAP operating expenses decreased to $85.6 million from $95.0 million in Q2 2025. Non-GAAP operating expenses grew 16% to $70.0 million reflecting R&D investments. Source

Product Launches and Market Expansion

  • Prosigna Breast Test launched in market: Launched Prosigna Breast Test in U.S. for early-stage HR+ breast cancer patients, meaningfully expanding ability to serve cancer care continuum. Source
  • TrueMRD Monitoring Test now available: Launched TrueMRD Monitoring Test for muscle-invasive bladder cancer patients, expanding platform into new disease indication. Source
  • Medicare coverage secured for TrueMRD: Secured Medicare coverage for TrueMRD platform, representing first Medicare coverage decision for whole-genome sequencing-based monitoring test. Source

Clinical Evidence Expansion

  • OPTIMA trial supports Prosigna clinical utility: New predictive evidence from OPTIMA trial published supporting Prosigna clinical utility. ENZAMET trial expanding Decipher clinical evidence base. Source
  • Nearly 60 presentations during quarter: Decipher and Afirma featured in nearly 60 abstracts and presentations during Q2, strengthening clinical validation and market awareness. Source

Cash Generation and Balance Sheet

  • Operating cash flow reached $81 million: Net cash from operations in first six months 2026 reached $81.0 million, an improvement of $42.1 million versus prior-year period. Source
  • Q2 generated $45.8 million operating cash: Q2 alone generated $45.8 million of cash from operations, supporting continued investment in growth. Source
  • Cash and investments total $485.2 million: Cash, cash equivalents and short-term investments totaled $485.2 million at quarter-end, providing strong financial flexibility. Source

Full-Year 2026 Guidance Raised

  • Total revenue guidance raised to $590-596M: Total revenue guidance raised to $590-596 million representing 14-15% growth, up from $582-592 million guidance. Source
  • Testing revenue guidance increased to $576-582M: Testing revenue guidance raised to $576-582 million representing 17-18% growth, up from $570-580 million guidance. Source
  • Adjusted EBITDA margin guidance >26 percent: Adjusted EBITDA margin guidance increased to greater than 26% from approximately 25%, reflecting operational leverage. Source

Figures management reported

FigureReported
Testing volume Q2 2026 Source48,389 tests, 14% growth
Decipher testing volume Q2 2026 Source~29,700 tests, 17% growth
Afirma testing volume Q2 2026 Source~18,600 tests, 10% growth
Testing revenue Q2 2026 Source$145.7 million, 19% growth

Earlier plans management reported on

  • Met: Both Prosigna Breast Test and TrueMRD Monitoring Test launched in Q2 2026 as previously indicated in Q1 guidance. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.