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Veracyte, Inc.: Q1 FY2026 earnings call

What management said about Q1 FY2026, from the documents filed with the SEC on 5 May 2026: press release. Guidance figures: 3 raised. The quarter’s numbers.

Key takeaways

  • Total and testing revenue grew: Total revenue was $139.1 million and testing revenue $135.1 million, each up on the first quarter of 2025, with testing growth driven by Decipher Prostate and Afirma. Source
  • Adjusted EBITDA margin widened: Adjusted EBITDA was $42.8 million, or 30.8% of revenue, against $24.7 million and 21.6% of revenue a year earlier. Source
  • Decipher and Afirma drove testing growth: Decipher revenue was $86.5 million and Afirma revenue $46.4 million; the company named both as drivers of testing revenue growth. Source
  • Gross margin rose on both bases: GAAP gross margin was 73%, up from 69%; non-GAAP gross margin was 76%, up from 72%. Source
  • Operating cash flow rose: Operating cash flow was $35.2 million, $29.9 million more than in the same period of 2025. Source
  • Prosigna LDT and TrueMRD launches upcoming: Management said the upcoming Prosigna LDT and TrueMRD launches are two of the most significant new products in company history, expanding reach in breast and bladder cancers. Source

“Our growing clinical evidence continues to set us apart, and this quarter strengthened it even further.”

Marc Stapley, Veracyte’s CEO

Guidance

AreaPeriodFigureAgainst last quarter
Total revenue Source2026$582 million to $592 million, or 13% to 14% growthRaised from $570 million to $582 million, or 10% to 13% growth
Testing revenue (excluding new tests) Source2026$570 million to $580 million, or 16% to 18% growthRaised from $560 million to $570 million, or 14% to 16% growth
Adjusted EBITDA margin Source2026greater than 26%Raised from approximately 25%

What changed from last quarter

  • Guidance raised: Total revenue guidance for 2026 was raised from the prior range. Source
  • Guidance raised: Testing revenue guidance for 2026, excluding new tests, was raised from the prior range. Source
  • Guidance raised: The adjusted EBITDA margin guidance was raised to greater than 26% from approximately 25%. Source
  • New: Two executive appointments were announced: Kevin Haas as Chief Development and Technology Officer and Tracy Ward as Chief Human Resources Officer. Source

Results and growth drivers

  • Total and testing revenue grew: Total revenue was $139.1 million and testing revenue $135.1 million, each up on the first quarter of 2025, with testing growth driven by Decipher Prostate and Afirma. Source
  • Diluted EPS and other income: Diluted EPS was $0.35 on GAAP net income of $28.7 million, and non-GAAP diluted EPS was $0.52. Other income, net was $7.3 million. Source
  • Adjusted EBITDA margin widened: Adjusted EBITDA was $42.8 million, or 30.8% of revenue, against $24.7 million and 21.6% of revenue a year earlier. Source
  • 2026 guidance raised on all three: Management raised all three 2026 guidance measures: total revenue, testing revenue and adjusted EBITDA margin. Figures are in the guidance list. Source

Products and revenue mix

  • Decipher and Afirma drove testing growth: Decipher revenue was $86.5 million and Afirma revenue $46.4 million; the company named both as drivers of testing revenue growth. Source
  • Product revenue rose 3%: Product revenue was $3.7 million, a smaller line within total revenue, rising 3% from a year earlier. Source
  • Biopharma revenue fell with Veracyte SAS: Biopharmaceutical and other revenue fell to $0.3 million as Veracyte SAS restructuring and liquidation proceedings progressed; the company called the decrease expected. Source

“We believe we are approaching an inflection point with the upcoming launches of Prosigna LDT and TrueMRD”

Marc Stapley, Veracyte’s CEO

Costs and margins

  • Gross margin rose on both bases: GAAP gross margin was 73%, up from 69%; non-GAAP gross margin was 76%, up from 72%. Source
  • Non-GAAP operating expenses rose 7%: Non-GAAP operating expenses reached $64.6 million; GAAP operating expenses were $78.5 million against $76.6 million. Source
  • R&D rose while G&A fell: GAAP research and development expense rose to $27.1 million from $17.7 million, while GAAP general and administrative expense fell to $23.7 million from $33.8 million. Source

Cash, capital and equity

  • Operating cash flow rose: Operating cash flow was $35.2 million, $29.9 million more than in the same period of 2025. Source
  • Cash and investments totaled $439.1 million: Cash, cash equivalents and short-term investments totaled $439.1 million at March 31, 2026. Source
  • Capital spending was $3.0 million: Purchases of property, plant and equipment were $3.0 million, against $1.8 million in the first quarter of 2025. Source
  • Equity award tax payments: Taxes paid on vested restricted stock units were $9.4 million; proceeds from option exercises and stock purchases were $2.7 million. Source

Clinical evidence and launches

  • Prosigna LDT and TrueMRD launches upcoming: Management said the upcoming Prosigna LDT and TrueMRD launches are two of the most significant new products in company history, expanding reach in breast and bladder cancers. Source
  • Phase III trials completed enrollment: Enrollment was completed for the GUIDANCE and G-MAJOR phase III trials of Decipher. Source
  • European Urology Oncology data published: Published data show Decipher can stratify risk among patients undergoing active surveillance, according to the company. Source

Leadership changes

  • Two senior executives appointed: Kevin Haas was appointed Chief Development and Technology Officer and Tracy Ward Chief Human Resources Officer. Source

Coming up, as management said on 5 May 2026

  • AUA meeting Decipher studies: More than 15 studies on Decipher Prostate and Decipher Bladder are to be presented at the AUA Annual Meeting the following week. Source

Figures management reported

FigureReported
Total volume Source47,615 tests, up 17%
Testing volume Source45,248 tests, up 19%
Decipher volume Sourceapproximately 28,000 tests, up 24%
Afirma volume Sourceapproximately 17,200 tests, up 12%

Risks management discussed

  • Operational: Restructuring and liquidation of Veracyte SAS produced $4.2 million of adjustments excluded from non-GAAP results. Source
  • Regulatory: Legal proceedings expenses of $0.6 million and an assessment of licensing and strategic investments of $1.7 million were excluded from non-GAAP results. Source

Earlier plans management reported on

  • Ahead: Management said volume growth and profitability in the quarter were above its expectations and profitability targets. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.