Taysha Gene Therapies, Inc. 13F holders
208 funds reported a position in Taysha Gene Therapies, Inc. in their 13F for the quarter ended 30 June 2026, together 299.6 million shares worth $2.06 billion. Against the quarter before, 38 opened a position, 99 added, 41 trimmed and 22 sold out; together they bought a net 31.5 million shares. The largest holders: Avoro Capital Advisors LLC, Ra Capital Management, L.P. and Goldman Sachs Group Inc.
Funds holding208+17 on Q1 2026
Shares they held299.6Mworth $2.06 billion
Net bought on the quarter31.5M sharesabout $216.6 million at the funds' values
Funds buying to selling137 to 63opened or added, to cut or sold
Opened 38Added 99Held 29Trimmed 41Sold out 22
What each fund did in TSHA against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in TSHA in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
3,241 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 29 reported a position in Taysha Gene Therapies, Inc.: 3 opened one, 13 added, 4 trimmed and 1 sold out, a net 61,062 shares bought.
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 6 reported a position in Taysha Gene Therapies, Inc. in a 13F for the quarter ended 30 June 2026. The largest: FMR LLC, 13.3 million shares worth $90.8 million, 0.0% of its reported book. Sold out: Renaissance Technologies, Point72 Asset Management. In the quarter, 2 funds added or opened a position and 5 trimmed or sold out; together they sold a net 1.4 million shares, about $9.3 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| FMR LLC | 13,336,413 | $90.8 million | 0.0% | -984,842 | trimmed | 30 June 2026 | 13F |
| Geode Capital Management | 6,560,394 | $44.7 million | 0.0% | +1,028,439 | added | 30 June 2026 | 13F |
| Norges Bank | 2,233,600 | $15.2 million | 0.0% | held | 30 June 2026 | 13F | |
| Millennium Management | 2,126,838 | $14.5 million | 0.0% | -1,154,982 | trimmed | 30 June 2026 | 13F |
| Citadel Advisors | 1,535,287 | $10.5 million | 0.0% | +1,124,152 | added | 30 June 2026 | 13F |
| Two Sigma Investments | 234,716 | $1.6 million | 0.0% | -507,365 | trimmed | 30 June 2026 | 13F |
| Renaissance Technologies | 0 | $0 | 0.0% | -413,203 | exited | 30 June 2026 | 13F |
| Point72 Asset Management | 0 | $0 | 0.0% | -461,856 | exited | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 23,888,888 | 7.97% | $162.7 million | 1.46% | +2,188,888 | 13F |
| Ra Capital Management, L.P. | 23,555,648 | 7.86% | $160.4 million | 1.39% | no change | 13F |
| Goldman Sachs Group Inc. | 22,713,118 | 7.58% | $154.7 million | 0.02% | +343,473 | 13F |
| BlackRock, Inc. | 20,691,927 | 6.91% | $140.9 million | 0.00% | +2,326,319 | 13F |
| Vestal Point Capital, LP | 19,415,000 | 6.48% | $132.2 million | 3.09% | +1,415,000 | 13F |
| Morgan Stanley | 16,487,479 | 5.50% | $112.3 million | 0.01% | -1,477,892 | 13F |
| RTW Investments, LP | 13,560,258 | 4.53% | $92.3 million | 0.79% | -119,990 | 13F |
| FMR LLC | 13,336,413 | 4.45% | $90.8 million | 0.00% | -984,842 | 13F |
| Vanguard Capital Management LLC | 12,478,595 | 4.17% | $85.0 million | 0.00% | +2,247,093 | 13F |
| State Street Corp. | 11,421,920 | 3.81% | $77.8 million | 0.00% | +212,842 | 13F |
| Siren, L.L.C. | 9,846,579 | 3.29% | $67.1 million | 1.36% | +1,016,666 | 13F |
| Octagon Capital Advisors LP | 9,693,244 | 3.24% | $66.0 million | 6.06% | +833,333 | 13F |
| Geode Capital Management, LLC | 6,560,394 | 2.19% | $44.7 million | 0.00% | +1,028,439 | 13F |
| Polar Capital Holdings Plc | 5,117,133 | 1.71% | $34.8 million | 0.10% | -537,207 | 13F |
| MPM Bioimpact LLC | 4,500,000 | 1.50% | $30.6 million | 1.87% | new | 13F |
| D. E. Shaw & Co., Inc. | 4,398,652 | 1.47% | $30.0 million | 0.02% | -28,649 | 13F |
| Baker Bros. Advisors LP | 4,004,756 | 1.34% | $27.3 million | 0.14% | no change | 13F |
| Wellington Management Group LLP | 3,975,605 | 1.33% | $27.1 million | 0.01% | +3,349,244 | 13F |
| Healthcare of Ontario Pension Plan Trust Fund | 3,885,501 | 1.30% | $26.5 million | 0.04% | +1,002,200 | 13F |
| GordonMD Global Investments LP | 723,185 | 0.24% | $24.5 million | 11.86% | -14,365 | 13F |
| Casdin Capital, LLC | 3,250,000 | 1.08% | $22.1 million | 1.11% | no change | 13F |
| Vanguard Portfolio Management LLC | 3,140,009 | 1.05% | $21.4 million | 0.00% | +1,117,511 | 13F |
| ADAR1 Capital Management, LLC | 3,040,466 | 1.01% | $20.7 million | 0.98% | +61,037 | 13F |
| Pictet Asset Management Holding SA | 2,770,701 | 0.92% | $18.9 million | 0.02% | +2,751,383 | 13F |
| Aberdeen Group plc | 2,327,152 | 0.78% | $15.8 million | 0.02% | +1,306,089 | 13F |
| Farallon Capital Management, L.l.c. | 2,250,000 | 0.75% | $15.3 million | 0.09% | new | 13F |
| Norges Bank | 2,233,600 | 0.75% | $15.2 million | 0.00% | 13F | |
| Northern Trust Corp. | 2,226,210 | 0.74% | $15.2 million | 0.00% | +411,892 | 13F |
| Charles Schwab Investment Management Inc. | 2,200,695 | 0.73% | $15.0 million | 0.00% | +392,096 | 13F |
| Millennium Management LLC | 2,126,838 | 0.71% | $14.5 million | 0.01% | -1,154,982 | 13F |
| Orbimed Advisors LLC | 2,000,000 | 0.67% | $13.6 million | 0.26% | new | 13F |
| Rice Hall James & Associates, LLC | 1,992,229 | 0.66% | $13.6 million | 0.66% | +47,558 | 13F |
| Vanguard Fiduciary Trust Co. | 1,896,474 | 0.63% | $12.9 million | 0.00% | +366,013 | 13F |
| B Group, Inc. | 1,800,556 | 0.60% | $12.3 million | 6.96% | no change | 13F |
| Affinity Asset Advisors, LLC | 1,750,000 | 0.58% | $11.9 million | 0.59% | +750,000 | 13F |
| Barclays PLC | 1,630,659 | 0.54% | $11.1 million | 0.00% | -1,181,351 | 13F |
| Citadel Advisors LLC | 1,535,287 | 0.51% | $10.5 million | 0.01% | +1,124,152 | 13F |
| Heights Capital Management, Inc. | 1,500,000 | 0.50% | $10.2 million | 2.36% | new | 13F |
| Seven Fleet Capital Management LP | 1,504,400 | 0.50% | $9.9 million | 1.64% | +878,692 | 13F |
| Palo Alto Investors LP | 1,391,382 | 0.46% | $9.5 million | 1.31% | no change | 13F |
| Bank of America Corp. | 1,372,845 | 0.46% | $9.3 million | 0.00% | -304,201 | 13F |
| Granahan Investment Management, LLC | 1,305,177 | 0.44% | $8.9 million | 0.32% | +421,936 | 13F |
| Quantum Private Wealth, LLC | 812,027 | 0.27% | $5.5 million | 1.42% | -37,185 | 13F |
| First Trust Advisors LP | 791,169 | 0.26% | $5.4 million | 0.00% | new | 13F |
| JPMorgan Chase & Co. | 766,282 | 0.26% | $5.2 million | 0.00% | +11,500 | 13F |
| Sands Capital Alternatives, LLC | 724,873 | 0.24% | $4.9 million | 0.81% | no change | 13F |
| Bank of New York Mellon Corp | 697,971 | 0.23% | $4.8 million | 0.00% | +89,848 | 13F |
| BNP Paribas Financial Markets | 640,035 | 0.21% | $4.4 million | 0.00% | +519,835 | 13F |
| Panagora Asset Management Inc. | 590,387 | 0.20% | $4.0 million | 0.01% | +408,223 | 13F |
| UBS Group AG | 588,427 | 0.20% | $4.0 million | 0.00% | +70,729 | 13F |
The 50 largest of the 208 funds that reported a position in TSHA in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on TSHA
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 115,000 | $783,150 | 30 June 2026 | 13F |
| Citadel Advisors | Puts | 62,900 | $428,349 | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 14 August 2026 | 13G/A | RA Capital Management, L.P. and 7 others | 32.9 million | 9.9% | 30 June 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 13 August 2026 | 13G/A | Morgan Stanley and 3 others | 16.2 million | 5.1% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | RTW Investments, LP and 3 others | 20.7 million | 7.0% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | Vestal Point Capital, LP and 3 others | 18.0 million | 6.3% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | RTW Investments, LP and 3 others | 23.4 million | 8.3% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G | Vestal Point Capital, LP and 3 others | 13.8 million | 5.0% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 5 February 2026 | 13G/A | FMR LLC and 3 others | 13.5 million | 4.9% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 21 January 2026 | 13G/A | BlackRock, Inc. and 1 other | 17.9 million | 6.5% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 14 November 2025 | 13G/A | RA Capital Management, L.P. and 7 others | 27.7 million | 9.9% | 30 September 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 November 2025 | 13G/A | Octagon Capital Advisors LP and 5 others | 9.1 million | 3.3% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 8 September 2026 | 505 | $5.60 | SEC |
| 4 September 2026 | 386 | $5.57 | SEC |
| 1 September 2026 | 22 | $5.69 | SEC |
| 24 August 2026 | 394 | $6.09 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.