greeksoup/ stock research

Tempus AI, Inc.: Q3 FY2026 earnings call

What management said about Q3 FY2026, from the documents filed with the SEC on 2 November 2026: press release. Guidance figures: 1 raised, 2 kept. The quarter’s numbers.

Key takeaways

  • Revenue rose 23% to $411.5 million: Total revenue was $411.5 million, up 23% from $334.2 million a year earlier. Nine-month revenue was $1,142.1 million, up from $904.6 million. Source
  • Adjusted EBITDA rose to $25.6 million: Adjusted EBITDA was $25.6 million, against $1.5 million in the third quarter of 2025. Non-GAAP income from operations was $14.4 million, against a loss of $(8.7) million. Source
  • Diagnostics revenue grew 20%: Diagnostics revenue was $303.5 million, against $252.9 million in the third quarter of 2025. Source
  • Oncology volume growth accelerated to 32%: Oncology volume growth accelerated to 32%, from 31% in the second quarter, according to the prior release. Source
  • Data and Applications revenue grew 33%: Data and Applications revenue was $108.1 million, against $81.3 million, with Insights revenue up 29%. The segment had grown 28% in the second quarter. Source
  • BMS licensing deal up to $137.5 million: Tempus is directly licensing oncology data and models to BMS for up to $137.5 million over five years. Source
  • Cash and securities reached $854.4 million: Cash and marketable securities were $854.4 million at quarter end, against $820.7 million at June 30, 2026. Source
  • Personalis acquisition cleared regulatory review: Regulatory review of the pending Personalis acquisition was cleared. Source

“Q3 was another record quarter, as we delivered $411.5 million of revenue, led by accelerating unit growth of 32% in our oncology business and increasing momentum of 33% revenue growth in Data & Applications,”

Eric Lefkofsky, founder and CEO of Tempus

Guidance

AreaPeriodFigureAgainst last quarter
Full-year 2026 revenue SourceFull year 2026$1.60 to $1.605 billionRaised from $1.595 to $1.605 billion
Full-year 2026 revenue growthFull year 2026~25%Kept
Adjusted EBITDA SourceFull year 2026~$65 millionKept

What changed from last quarter

  • Guidance raised: Full-year 2026 revenue guidance was raised to $1.60 to $1.605 billion; the lower end rose from $1.595 billion. Source
  • Guidance kept: Full-year 2026 Adjusted EBITDA guidance of about $65 million was maintained. Source
  • New: Multi-year collaboration with Merck and Moderna announced to support commercialization of individualized neoantigen therapy drugs. Source
  • New: Direct licensing of oncology data and models to BMS announced in October. Source
  • New: Initiative announced to build a research platform of 100,000 whole genomes linked to longitudinal clinical information. Source
  • New: Regulatory review of the pending Personalis acquisition was cleared. Source
  • New: Two FDA 510(k) clearances received for Tempus ECG-PH and ECG-MR, extending the non-invasive AI cardiology products. Source

Results and growth drivers

  • Revenue rose 23% to $411.5 million: Total revenue was $411.5 million, up 23% from $334.2 million a year earlier. Nine-month revenue was $1,142.1 million, up from $904.6 million. Source
  • Net loss narrowed to $14.9 million: Net loss was $(14.9) million, against $(80.0) million in the third quarter of 2025. The net loss included $42.8 million of unrealized gains on marketable securities. Source
  • Adjusted EBITDA rose to $25.6 million: Adjusted EBITDA was $25.6 million, against $1.5 million in the third quarter of 2025. Non-GAAP income from operations was $14.4 million, against a loss of $(8.7) million. Source
  • Non-GAAP net income turned positive: Non-GAAP net income was $13.4 million, or $0.07 per share, against a non-GAAP net loss of $(19.6) million a year earlier. Source

Diagnostics segment

  • Diagnostics revenue grew 20%: Diagnostics revenue was $303.5 million, against $252.9 million in the third quarter of 2025. Source
  • Oncology volume growth accelerated to 32%: Oncology volume growth accelerated to 32%, from 31% in the second quarter, according to the prior release. Source
  • Hereditary revenue growth slowed to 3%: Hereditary revenue grew 3%, against 5% in the second quarter. This slower Hereditary growth offset part of the Oncology volume gain in Diagnostics. Source
  • MRD test volume up 300%: Minimal residual disease volume was about 12,000 tests, against about 9,000 tests in the second quarter, according to the prior release. Source

“These results reinforce the durability of our model as our best-in-class diagnostic platform enhances our data and AI offerings, distinguishes our business from our many competitors, and helps drive our performance quarter after quarter.”

Eric Lefkofsky, founder and CEO of Tempus

Data and Applications segment

  • Data and Applications revenue grew 33%: Data and Applications revenue was $108.1 million, against $81.3 million, with Insights revenue up 29%. The segment had grown 28% in the second quarter. Source
  • Pathos-related revenue declined: Pathos AI related-party revenue in the segment was $22.1 million, against $24.9 million. SB Tempus related-party revenue was zero, against $6.3 million. Source
  • Nine-month segment revenue rose: Nine-month Data and Applications revenue was $288.2 million, against $216.1 million in the prior-year period. Source

Margins and operating costs

  • Gross margin rose to 64.8%: Gross margin was 64.8%, against 62.8% a year earlier. Non-GAAP gross margin was 65.9%, against 63.6%. Source
  • Data and Applications margin improved: Data and Applications gross margin was 71.5%, against 68.5%. Diagnostics gross margin was 62.4%, against 61.0%. Source
  • Operating expenses rose on SG&A: Operating expenses were $323.6 million, against $270.9 million, with SG&A at $231.9 million. Non-GAAP operating expenses were $256.8 million, against $221.2 million. Source
  • Stock-based compensation expense rose: Stock-based compensation expense was $48.1 million, against $34.0 million a year earlier. Nine-month stock-based compensation was $154.9 million, against $79.4 million. Source

Data licensing and collaborations

  • BMS licensing deal up to $137.5 million: Tempus is directly licensing oncology data and models to BMS for up to $137.5 million over five years. Source
  • Alzheimer's and dementia data licensing: BMS and Pathos are licensing data for patients with Alzheimer's or dementia for $55 million over five years, extending the platform beyond oncology. Source
  • Merck and Moderna neoantigen collaboration: Multi-year collaboration to support potential commercialization of intismeran autogene, being evaluated with KEYTRUDA in resected melanoma and other cancer types. Source

Cash, debt and share count

  • Cash and securities reached $854.4 million: Cash and marketable securities were $854.4 million at quarter end, against $820.7 million at June 30, 2026. Source
  • Operating cash outflow narrowed: Net cash used in operating activities was $71.6 million for the nine months, against $181.3 million a year earlier. Purchases of property and equipment were $23.7 million. Source
  • Convertible note proceeds lower this year: Nine-month proceeds from convertible senior notes were $443.1 million, net of the initial purchasers' discount, against $726.5 million a year earlier. Source
  • Class A shares outstanding increased: Class A shares outstanding were 177.2 million at September 30, 2026, up from 173.2 million at December 31, 2025. Weighted-average shares were 181.3 million for the quarter. Source

Personalis acquisition and product milestones

  • Personalis acquisition cleared regulatory review: Regulatory review of the pending Personalis acquisition was cleared. Source
  • Personalis deal priced at $16.25 per share: The prior release said Tempus agreed to acquire Personalis for $16.25 per share, about $1.5 billion enterprise value, to integrate its NeXT Personal MRD technology.
  • 100,000-genome research platform announced: An initiative was announced to build a research platform of 100,000 whole genomes linked to longitudinal clinical information over several years. Source
  • Two FDA clearances for ECG products: Two 510(k) clearances from the FDA were received for Tempus ECG-PH and ECG-MR, extending the non-invasive AI cardiology products. Source

Coming up, as management said on 2 November 2026

  • Personalis shareholder vote on November 30: Personalis shareholder meeting to approve the acquisition is planned for November 30, 2026. Source
  • Personalis closing expected late Q4 or early 2027: The prior release said the Personalis transaction is expected to close in late Q4 2026 or early 2027, and that guidance assumed no impact from it.

Figures management reported

FigureReported
Data licensing bookings, year to date Sourcemore than $550 million

Risks management discussed

  • Financial: Management said the forecast items excluded from its Adjusted EBITDA reconciliation are not within its control and may vary greatly between periods. Source

Earlier plans management reported on

  • Not stated: Management continued to expect Adjusted EBITDA of about $65 million for 2026. The release does not state progress against this figure. Source
  • Not stated: The prior release gave expected closing timing for the Personalis transaction. The current release does not restate it.

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.