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Tempus AI, Inc.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 30 July 2026: press release. Guidance figures: 1 raised, 1 kept. The quarter’s numbers.

Key takeaways

  • Revenue rose 22% to $382.5 million: Total revenue was $382.5 million for the quarter, up from $314.6 million a year earlier. Six-month revenue was $730.6 million, up from $570.4 million. Source
  • Oncology volume growth reached 31%: Oncology volume grew 31% year-over-year, up from 28% in the prior quarter. Oncology volume is the largest driver cited for Diagnostics growth. Source
  • Diagnostics revenue up 20%: Diagnostics revenue was $289.3 million, up 20%, driven by Oncology volume growth. Source
  • Data and Applications revenue up 28%: Data and Applications revenue was $93.2 million, up 28%. Insights revenue grew 36% year-over-year. Source
  • MRD volume reached 9,000 tests: MRD volume was 9,000 tests, up from 6,500 last quarter. Tempus Preview now gives preliminary results for high-impact biomarkers within about 24 hours of tissue receipt. Source
  • Large deals drove about $200 million bookings: Large deals with BioNTech, Daiichi Sankyo, Level Set Bio and Incyte Pharmaceuticals contributed to about $200 million of total bookings this quarter. Source
  • Personalis MRD technology to be integrated: Personalis' NeXT Personal MRD technology is to be integrated into Tempus' diagnostic platform, under the agreement announced July 20, 2026. Source

“Our strategy is working given the investments we have made in AI over the past several years are driving some of the best growth rates we have seen in our two largest businesses - Oncology Diagnostics and Data Licensing.”

Eric Lefkofsky, Founder and CEO of Tempus

Guidance

AreaPeriodFigureAgainst last quarter
Revenue SourceFull year 2026$1.595 to $1.605 billionRaised from $1.59 to $1.60 billion
Adjusted EBITDA SourceFull year 2026~$65 millionKept

What changed from last quarter

  • Guidance raised: 2026 revenue guidance raised to $1.595 to $1.605 billion from $1.59 to $1.60 billion. Source
  • Guidance kept: Full-year 2026 Adjusted EBITDA guidance of about $65 million was kept. Source
  • New: Agreement announced July 20, 2026 to acquire Personalis at $16.25 per share, about $1.5 billion enterprise value. Source
  • New: FDA approved xT Tumor Only, which the company said will move tissue testing to ADLT pricing. Source

Results and growth drivers

  • Revenue rose 22% to $382.5 million: Total revenue was $382.5 million for the quarter, up from $314.6 million a year earlier. Six-month revenue was $730.6 million, up from $570.4 million. Source
  • Oncology volume growth reached 31%: Oncology volume grew 31% year-over-year, up from 28% in the prior quarter. Oncology volume is the largest driver cited for Diagnostics growth. Source
  • Net income of $5.6 million: Net income was $5.6 million, or $0.03 per diluted share, compared with a net loss of $42.8 million in the second quarter of 2025. Source
  • Adjusted EBITDA reached $8.0 million: Adjusted EBITDA was $8.0 million, compared with negative $5.6 million a year earlier. Non-GAAP loss from operations was $2.7 million, against $17.0 million a year earlier. Source

Segments and revenue lines

  • Diagnostics revenue up 20%: Diagnostics revenue was $289.3 million, up 20%, driven by Oncology volume growth. Source
  • Data and Applications revenue up 28%: Data and Applications revenue was $93.2 million, up 28%. Insights revenue grew 36% year-over-year. Source
  • Hereditary revenue grew 5%: Hereditary revenue grew 5% in the quarter, below the 31% Oncology volume growth cited for Diagnostics. Source

“With clinical adoption and reimbursement momentum building, we believe we are collectively well positioned to capture this”

Eric Lefkofsky, Founder and CEO of Tempus

Products and customers

  • MRD volume reached 9,000 tests: MRD volume was 9,000 tests, up from 6,500 last quarter. Tempus Preview now gives preliminary results for high-impact biomarkers within about 24 hours of tissue receipt. Source
  • First lab with dual CDx approval: The company became the first laboratory to hold FDA companion diagnostic approval for both tumor-only and tumor-normal comprehensive genomic profiling. Source
  • Keck School of Medicine collaboration: The collaboration with the Keck School of Medicine of USC covers the AI platform, molecular diagnostics and clinical trial matching across more than 1.5 million annual patient visits. Source
  • Digital pathology consortium launched: The IMS Open-Source Consortium with Yale New Haven Hospital and Memorial Sloan Kettering Cancer Center aims to standardize digital pathology. Source

Costs, margins and pricing

  • Gross margin rose to 64.4%: Gross profit was $246.5 million, up 26%. Gross margin was 64.4%, against 62.0% a year earlier. Non-GAAP gross margin was 65.7%, up from 62.8%. Source
  • Data and Applications margin lower: Data and Applications gross margin was 70.2%, down from 72.7% a year earlier. Diagnostics gross margin rose to 62.6% from 58.8%. Source
  • First-quarter stock compensation was $56.3 million: The first-quarter net loss carried $56.3 million of stock compensation and related payroll taxes. The second-quarter comparable amount was $55.6 million.

Demand and the order book

  • About $200 million of new licenses: The company signed about $200 million of new Data and Applications licenses in the quarter. Source
  • Large deals drove about $200 million bookings: Large deals with BioNTech, Daiichi Sankyo, Level Set Bio and Incyte Pharmaceuticals contributed to about $200 million of total bookings this quarter. Source

Capital, cash and returns to shareholders

  • Cash and securities reached $820.7 million: Cash and marketable securities were $820.7 million at June 30, 2026, up from $643.8 million at March 31, 2026. Source
  • $460 million convertible notes issued: The company completed a $460 million offering of 0.0% convertible senior notes due 2032. Source
  • Operating cash use was $80.8 million: Net cash used in operating activities was $80.8 million for the six months ended June 30, 2026, compared with $61.5 million a year earlier. Source

Strategy and investment

  • Personalis MRD technology to be integrated: Personalis' NeXT Personal MRD technology is to be integrated into Tempus' diagnostic platform, under the agreement announced July 20, 2026. Source
  • Oncology foundation model delivered to AstraZeneca: Management reported initial results from the first version of its oncology foundation model, which was delivered to AstraZeneca. Source
  • Existing Personalis collaboration cited: Management said the existing collaboration with Personalis already combines MRD technology with Tempus' commercial infrastructure. Source

Coming up, as management said on 30 July 2026

  • Personalis deal expected to close: Management expects the Personalis transaction to close in late Q4 2026 or early 2027. Guidance does not include its impact. Source

Figures management reported

FigureReported
Large customers SourceBioNTech, Daiichi Sankyo, Level Set Bio, Incyte Pharmaceuticals

Risks management discussed

  • External: Revenue guidance excludes any effect from the pending Personalis acquisition, so the deal's timing and terms are not reflected in the figures. Source

Earlier plans management reported on

  • Not stated: Management restated its full-year 2026 Adjusted EBITDA expectation, describing it as a continuing expectation. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.