Madrigal Pharmaceuticals, Inc. 13F holders
414 funds reported a position in Madrigal Pharmaceuticals, Inc. in their 13F for the quarter ended 30 June 2026, together 23.7 million shares worth $12.73 billion. Against the quarter before, 66 opened a position, 144 added, 131 trimmed and 41 sold out; together they sold a net 410,796 shares. The largest holders: Baker Bros. Advisors LP, RTW Investments, LP and Jupiter Topco LLC.
Funds holding414+34 on Q1 2026
Shares they held23.7Mworth $12.73 billion
Net sold on the quarter410,796 sharesabout $220.5 million at the funds' values
Funds buying to selling210 to 172opened or added, to cut or sold
Opened 66Added 144Held 71Trimmed 131Sold out 41
What each fund did in MDGL against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in MDGL in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
2,671 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 75 reported a position in Madrigal Pharmaceuticals, Inc.: 14 opened one, 15 added, 17 trimmed and 6 sold out, a net 185,709 shares sold.
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 8 reported a position in Madrigal Pharmaceuticals, Inc. in a 13F for the quarter ended 30 June 2026. The largest: Citadel Advisors, 507,233 shares worth $272.4 million, 0.2% of its reported book. New this quarter: Two Sigma Investments. Sold out: Bridgewater Associates. In the quarter, 3 funds added or opened a position and 5 trimmed or sold out; together they sold a net 260,547 shares, about $139.9 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Citadel Advisors | 507,233 | $272.4 million | 0.2% | +53,390 | added | 30 June 2026 | 13F |
| Geode Capital Management | 374,880 | $201.3 million | 0.0% | -80,990 | trimmed | 30 June 2026 | 13F |
| FMR LLC | 356,201 | $191.3 million | 0.0% | -155,527 | trimmed | 30 June 2026 | 13F |
| Norges Bank | 213,886 | $114.8 million | 0.0% | held | 30 June 2026 | 13F | |
| Point72 Asset Management | 137,029 | $73.6 million | 0.1% | -88,481 | trimmed | 30 June 2026 | 13F |
| Millennium Management | 81,196 | $43.6 million | 0.0% | +40,343 | added | 30 June 2026 | 13F |
| Renaissance Technologies | 45,942 | $24.7 million | 0.0% | -25,928 | trimmed | 30 June 2026 | 13F |
| Two Sigma Investments | 566 | $303,914 | 0.0% | +566 | new | 30 June 2026 | 13F |
| Bridgewater Associates | 0 | $0 | 0.0% | -3,920 | exited | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| Baker Bros. Advisors LP | 2,143,131 | 9.04% | $1.15 billion | 5.79% | +1,430 | 13F |
| RTW Investments, LP | 1,993,687 | 8.41% | $1.07 billion | 9.14% | no change | 13F |
| Jupiter Topco LLC | 1,936,099 | 8.16% | $1.04 billion | 0.42% | first 13F | 13F |
| Avoro Capital Advisors LLC | 1,833,333 | 7.73% | $984.4 million | 8.84% | +15,152 | 13F |
| Paulson & Co. Inc. | 1,340,020 | 5.65% | $719.5 million | 27.93% | -52,168 | 13F |
| BlackRock, Inc. | 1,200,770 | 5.06% | $644.8 million | 0.01% | -359,195 | 13F |
| Vanguard Capital Management LLC | 835,668 | 3.52% | $448.7 million | 0.01% | +8,524 | 13F |
| Wellington Management Group LLP | 825,714 | 3.48% | $443.4 million | 0.08% | +130,756 | 13F |
| Vanguard Portfolio Management LLC | 781,731 | 3.30% | $419.8 million | 0.02% | -59,414 | 13F |
| State Street Corp. | 527,057 | 2.22% | $283.0 million | 0.01% | -82,468 | 13F |
| Citadel Advisors LLC | 507,233 | 2.14% | $272.4 million | 0.16% | +53,390 | 13F |
| UBS Group AG | 401,708 | 1.69% | $215.7 million | 0.03% | +283,929 | 13F |
| Geode Capital Management, LLC | 374,880 | 1.58% | $201.3 million | 0.01% | -80,990 | 13F |
| FMR LLC | 356,201 | 1.50% | $191.3 million | 0.01% | -155,527 | 13F |
| William Blair Investment Management, LLC | 324,123 | 1.37% | $174.0 million | 0.52% | -16,396 | 13F |
| Invesco Ltd. | 301,435 | 1.27% | $161.9 million | 0.01% | -28,084 | 13F |
| Armistice Capital, LLC | 288,000 | 1.21% | $154.6 million | 4.28% | +23,417 | 13F |
| Lord, Abbett & Co. LLC | 281,500 | 1.19% | $151.2 million | 0.45% | +38,774 | 13F |
| Assenagon Asset Management S.A. | 248,428 | 1.05% | $133.4 million | 0.09% | 13F | |
| Goldman Sachs Group Inc. | 246,280 | 1.04% | $132.2 million | 0.01% | -31,091 | 13F |
| Polar Capital Holdings Plc | 244,274 | 1.03% | $131.2 million | 0.37% | -45,036 | 13F |
| Ameriprise Financial Inc. | 231,205 | 0.97% | $124.1 million | 0.03% | +133,024 | 13F |
| Norges Bank | 213,886 | 0.90% | $114.8 million | 0.01% | 13F | |
| Artisan Partners Limited Partnership | 210,205 | 0.89% | $112.9 million | 0.18% | +26,665 | 13F |
| Pictet Asset Management Holding SA | 192,896 | 0.81% | $103.5 million | 0.10% | +5,656 | 13F |
| Jane Street Group, LLC | 191,541 | 0.81% | $102.8 million | 0.07% | +155,703 | 13F |
| Price T Rowe Associates Inc. | 187,226 | 0.79% | $100.5 million | 0.01% | -140,884 | 13F |
| AllianceBernstein L.P. | 189,458 | 0.80% | $99.2 million | 0.03% | +64,011 | 13F |
| Charles Schwab Investment Management Inc. | 184,324 | 0.78% | $99.0 million | 0.01% | -32,396 | 13F |
| Toronto Dominion Bank | 181,432 | 0.77% | $97.4 million | 0.16% | +50,972 | 13F |
| Rock Springs Capital Management LP | 174,999 | 0.74% | $94.0 million | 4.59% | +4,000 | 13F |
| Hood River Capital Management LLC | 169,084 | 0.71% | $90.8 million | 0.66% | -80,427 | 13F |
| Holocene Advisors, LP | 152,924 | 0.64% | $82.1 million | 0.19% | new | 13F |
| Susquehanna International Group, LLP | 148,610 | 0.63% | $79.8 million | 0.07% | +126,394 | 13F |
| Morgan Stanley | 139,009 | 0.59% | $74.6 million | 0.00% | -52,285 | 13F |
| Point72 Asset Management, L.P. | 137,029 | 0.58% | $73.6 million | 0.12% | -88,481 | 13F |
| Bank of America Corp. | 134,036 | 0.57% | $72.0 million | 0.01% | -55,491 | 13F |
| Bank of New York Mellon Corp | 128,520 | 0.54% | $69.0 million | 0.01% | -7,388 | 13F |
| Woodline Partners LP | 125,899 | 0.53% | $67.6 million | 0.21% | no change | 13F |
| Vanguard Fiduciary Trust Co. | 121,583 | 0.51% | $65.3 million | 0.01% | -6,496 | 13F |
| Clearbridge Investments, LLC | 109,325 | 0.46% | $58.7 million | 0.05% | +84,878 | 13F |
| Erste Asset Management GmbH | 110,210 | 0.46% | $58.1 million | 0.45% | -50,000 | 13F |
| Marshall Wace, LLP | 101,859 | 0.43% | $54.7 million | 0.05% | +79,957 | 13F |
| Fiera Capital Corp | 99,857 | 0.42% | $53.6 million | 0.20% | -74,154 | 13F |
| American Century Companies Inc. | 99,396 | 0.42% | $53.4 million | 0.02% | -64,537 | 13F |
| Northern Trust Corp. | 98,510 | 0.42% | $52.9 million | 0.01% | -50,704 | 13F |
| New York State Common Retirement Fund | 94,743 | 0.40% | $50.9 million | 0.06% | +19,614 | 13F |
| Westfield Capital Management Co. LP | 93,931 | 0.40% | $50.4 million | 0.17% | -882 | 13F |
| HRT Financial LP | 84,634 | 0.36% | $45.4 million | 0.08% | new | 13F |
| Deutsche Bank AG | 83,916 | 0.35% | $45.1 million | 0.01% | -14,151 | 13F |
The 50 largest of the 414 funds that reported a position in MDGL in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on MDGL
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Puts | 94,000 | $50.5 million | 30 June 2026 | 13F |
| Citadel Advisors | Calls | 86,900 | $46.7 million | 30 June 2026 | 13F |
| Millennium Management | Calls | 36,000 | $19.3 million | 30 June 2026 | 13F |
| Two Sigma Investments | Puts | 6,700 | $3.6 million | 30 June 2026 | 13F |
| Point72 Asset Management | Calls | 3,400 | $1.8 million | 30 June 2026 | 13F |
| Two Sigma Investments | Calls | 3,200 | $1.7 million | 30 June 2026 | 13F |
| Point72 Asset Management | Puts | 2,200 | $1.2 million | 30 June 2026 | 13F |
| Millennium Management | Puts | 1,300 | $698,035 | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 29 July 2026 | 13G/A | BlackRock, Inc. and 1 other | 1.1 million | 4.6% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | Janus Henderson Group PLC and 1 other | 2.0 million | 8.8% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | Paulson & Co. Inc. and 1 other | 1.4 million | 6.1% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 27 March 2026 | 13G/A | The Vanguard Group and 1 other | 0 | 0.0% | 13 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | Janus Henderson Group PLC and 1 other | 1.6 million | 7.0% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | Paulson & Co. Inc. and 1 other | 1.7 million | 7.5% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 12 December 2025 | 13D/A | Rebecca Taub, M.D. | 1.8 million | 7.8% | 10 December 2025 | No changes, except that the Reporting Person no longer serves as Chief Medical Officer of the Issuer; the Reporting Person serves as Senior Scientific and Medical Advisor of the Issuer and continues to serve as a member of the Board of Dire | EDGAR |
| 12 December 2025 | 13D/A | Paul A Friedman, M.D. | 1.8 million | 7.8% | 10 December 2025 | No changes, except that the Reporting Person no longer serves as Chairman of the Board and Chief Executive Officer of the Issuer; the Reporting Person continues to serve as a member of the Board of Directors of the Issuer. | EDGAR |
| 14 November 2025 | 13G/A | Janus Henderson Group PLC and 1 other | 1.8 million | 8.3% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 15 September 2026 | 3 | $540.06 | SEC |
| 28 August 2026 | 1,165 | $543.69 | SEC |
| 20 August 2026 | 253 | $540.16 | SEC |
| 18 August 2026 | 22 | $524.87 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.