Defilade Capital Management, L.P.
Defilade Capital Management, L.P. reported 39 US-listed holdings worth $746.9 million in its 13F for the quarter ended 30 June 2026, filed 14 August 2026. Its largest: Eli Lilly & Co. (6.3%), Pfizer Inc. (5.7%) and Veeva Systems Inc. (5.6%). Against the quarter before, it opened 20 positions, added to 8, trimmed 10 and sold out of 12.
The 14 largest of its 39 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.
What the fund reported holding at each quarter's end; hover a bar for the number of positions
What its reported holdings returned
Held through each quarter, the holdings it reported returned +3.1% over the 2 quarters to 30 June 2026, against +9.5% for the S&P 500.
Not the fund's own return: each 13F's holdings are kept unchanged until the next one, so trades inside a quarter, dividends, cash and fees are left out. A rough guide to how its picks have done over time.
What it did on the quarter
Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held
Opened 20
- Veeva Systems Inc. VEEV$42.0 million
- Biomarin Pharmaceutical Inc. BMRN$39.0 million
- Baxter International Inc. BAX$31.1 million
- Insulet Corp. PODD$26.9 million
- Thermo Fisher Scientific Inc. TMO$26.0 million
- Abbott Laboratories ABT$25.9 million
- Ascendis Pharma A/s ASND$25.3 million
- Solventum Corp. SOLV$24.4 million
and 12 more in the table below
Added to 8
- Eli Lilly & Co. LLY+18,390 shares · +89%
- Insmed Inc. INSM+86,929 shares · +45%
- Pfizer Inc. PFE+307,614 shares · +21%
- PTC Therapeutics, Inc. PTCT+57,534 shares · +15%
- Oric Pharmaceuticals Inc. ORIC+204,762 shares · +24%
- Cogent Biosciences Inc. COGT+40,851 shares · +12%
- Evommune Inc. EVMN+114,556 shares · +17%
- Ocular Therapeutix Inc. OCUL+2,641 shares · +0%
Trimmed 10
- Revolution Medicines, Inc. RVMD-233,145 shares · -74%
- Denali Therapeutics Inc. DNLI-968,103 shares · -71%
- Zimmer Biomet Holdings, Inc. ZBH-261,735 shares · -45%
- ICU Medical Inc. ICUI-148,591 shares · -58%
- Globus Medical Inc. GMED-214,713 shares · -61%
- Pacs Group Inc. PACS-388,505 shares · -64%
- Lantheus Holdings, Inc. LNTH-116,739 shares · -47%
- Olema Pharmaceuticals Inc. OLMA-579,778 shares · -39%
and 2 more in the table below
Sold out of 12
- Henry Schein Inc. HSIC$46.0 million last quarter
- Becton Dickinson & Co. BDX$43.9 million last quarter
- Dexcom Inc. DXCM$33.8 million last quarter
- Intuitive Surgical Inc. ISRG$31.2 million last quarter
- Neurocrine Biosciences Inc. NBIX$27.7 million last quarter
- Integer Holdings Corp. ITGR$18.7 million last quarter
- Biogen Inc. BIIB$17.7 million last quarter
- Tandem Diabetes Care Inc. TNDM$14.6 million last quarter
What it holds
| Company | Shares | Value | Of its book | Change in shares |
|---|---|---|---|---|
| Eli Lilly & Co. LLY | 39.1K | $46.9 million | 6.28% | +18.4K |
| Pfizer Inc. PFE | 1.8M | $42.7 million | 5.71% | +307.6K |
| Veeva Systems Inc. VEEV | 236.7K | $42.0 million | 5.62% | new |
| Biomarin Pharmaceutical Inc. BMRN | 682.0K | $39.0 million | 5.22% | new |
| PTC Therapeutics, Inc. PTCT | 433.7K | $35.4 million | 4.74% | +57.5K |
| Baxter International Inc. BAX | 1.5M | $31.1 million | 4.17% | new |
| Insmed Inc. INSM | 281.8K | $30.0 million | 4.02% | +86.9K |
| Zimmer Biomet Holdings, Inc. ZBH | 317.4K | $27.3 million | 3.66% | -261.7K |
| Insulet Corp. PODD | 176.9K | $26.9 million | 3.61% | new |
| Thermo Fisher Scientific Inc. TMO | 51.9K | $26.0 million | 3.49% | new |
| Abbott Laboratories ABT | 285.8K | $25.9 million | 3.47% | new |
| Ascendis Pharma A/s ASND | 94.8K | $25.3 million | 3.39% | new |
| Solventum Corp. SOLV | 316.5K | $24.4 million | 3.27% | new |
| Medtronic plc MDT | 303.3K | $23.7 million | 3.18% | new |
| Elanco Animal Health Inc. ELAN | 864.1K | $21.3 million | 2.85% | -67.0K |
| Agios Pharmaceuticals Inc. AGIO | 546.8K | $20.3 million | 2.72% | new |
| Envista Holdings Corp. NVST | 726.1K | $19.1 million | 2.56% | new |
| Revolution Medicines, Inc. RVMD | 82.8K | $15.5 million | 2.08% | -233.1K |
| ICU Medical Inc. ICUI | 105.7K | $15.5 million | 2.07% | -148.6K |
| Cogent Biosciences Inc. COGT | 393.4K | $15.2 million | 2.04% | +40.9K |
| Lantheus Holdings, Inc. LNTH | 132.7K | $14.7 million | 1.97% | -116.7K |
| Ocular Therapeutix Inc. OCUL | 1.5M | $14.6 million | 1.96% | +2.6K |
| Eledon Pharmaceuticals Inc. ELDN | 3.5M | $13.9 million | 1.86% | -38.8K |
| Tyra Biosciences Inc. TYRA | 376.9K | $12.0 million | 1.61% | new |
| Olema Pharmaceuticals Inc. OLMA | 924.8K | $11.6 million | 1.55% | -579.8K |
| Oric Pharmaceuticals Inc. ORIC | 1.0M | $11.3 million | 1.52% | +204.8K |
| Larimar Therapeutics Inc. LRMR | 3.7M | $11.2 million | 1.50% | new |
| Globus Medical Inc. GMED | 139.6K | $11.0 million | 1.48% | -214.7K |
| Enovis Corp. ENOV | 531.9K | $11.0 million | 1.47% | new |
| Evommune Inc. EVMN | 793.1K | $10.5 million | 1.41% | +114.6K |
| Teleflex Inc. TFX | 80.1K | $10.2 million | 1.36% | new |
| Denali Therapeutics Inc. DNLI | 391.9K | $10.1 million | 1.35% | -968.1K |
| Glaukos Corp. GKOS | 66.5K | $9.3 million | 1.24% | new |
| Staar Surgical Co. STAA | 322.1K | $9.2 million | 1.24% | new |
| Pacs Group Inc. PACS | 215.7K | $9.2 million | 1.23% | -388.5K |
| Crinetics Pharmaceuticals in CRNX | 239.4K | $9.0 million | 1.20% | new |
| LivaNova plc LIVN | 107.4K | $8.8 million | 1.18% | new |
| Black Diamond Therapeutics I BDTX | 1.7M | $3.1 million | 0.41% | new |
| Mereo Biopharma Group PLC MREO | 7.6M | $2.4 million | 0.32% | no change |