Design Therapeutics, Inc. 13F holders
136 funds reported a position in Design Therapeutics, Inc. in their 13F for the quarter ended 30 June 2026, together 43.3 million shares worth $626.5 million. Against the quarter before, 26 opened a position, 61 added, 32 trimmed and 16 sold out; together they bought a net 5.3 million shares. The largest holders: SR One Capital Management, LP, Logos Global Management LP and Baker Bros. Advisors LP.
Funds holding136+11 on Q1 2026
Shares they held43.3Mworth $626.5 million
Net bought on the quarter5.3M sharesabout $76.9 million at the funds' values
Funds buying to selling87 to 48opened or added, to cut or sold
Opened 26Added 61Held 16Trimmed 32Sold out 16
What each fund did in DSGN against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in DSGN in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
3,241 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 22 reported a position in Design Therapeutics, Inc.: 2 opened one, 10 added, 4 trimmed and 2 sold out, a net 48,136 shares bought.
| Fund | Change in shares | Shares now | Status | Filing |
|---|---|---|---|---|
| China Universal Asset Management Co., Ltd. | +22,479 | 112,419 | added | 13F |
| Y-Intercept (Hong Kong) Ltd | +19,558 | 32,468 | added | 13F |
| Profund Advisors LLC | +14,351 | 14,351 | new | 13F |
| Nisa Investment Advisors, LLC | -11,700 | 3,124 | trimmed | 13F |
| Caitong International Asset Management Co., Ltd | +2,833 | 4,092 | added | 13F |
| Sterling Capital Management LLC | +901 | 1,009 | added | 13F |
| State of Wyoming | -812 | 1,754 | trimmed | 13F |
| Gamma Investing LLC | +685 | 2,135 | added | 13F |
| Oppenheimer & Co. Inc. | -441 | 31,646 | trimmed | 13F |
| Mirae Asset Global Investments Co., Ltd. | +405 | 3,198 | added | 13F |
| SJS Investment Consulting Inc. | +268 | 272 | added | 13F |
| Private Wealth Management Group, LLC | -112 | 421 | trimmed | 13F |
| GF Fund Management Co. Ltd | +106 | 1,315 | added | 13F |
| Parkside Financial Bank & Trust | +70 | 70 | new | 13F |
| Farther Finance Advisors, LLC | +18 | 38 | added | 13F |
| True Wealth Design, LLC | +5 | 23 | added | 13F |
| MassMutual Private Wealth & Trust, FSB | -239 | 0 | sold out | 13F |
| Stone House Investment Management, LLC | -239 | 0 | sold out | 13F |
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 7 reported a position in Design Therapeutics, Inc. in a 13F for the quarter ended 30 June 2026. The largest: Point72 Asset Management, 2.4 million shares worth $34.2 million, 0.1% of its reported book. In the quarter, 3 funds added or opened a position and 4 trimmed or sold out; together they sold a net 226,769 shares, about $3.3 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Point72 Asset Management | 2,366,453 | $34.2 million | 0.1% | -356,301 | trimmed | 30 June 2026 | 13F |
| Geode Capital Management | 958,417 | $13.9 million | 0.0% | +265,899 | added | 30 June 2026 | 13F |
| FMR LLC | 776,462 | $11.2 million | 0.0% | -21,949 | trimmed | 30 June 2026 | 13F |
| Renaissance Technologies | 387,913 | $5.6 million | 0.0% | -20,287 | trimmed | 30 June 2026 | 13F |
| Millennium Management | 147,714 | $2.1 million | 0.0% | +38,786 | added | 30 June 2026 | 13F |
| Citadel Advisors | 81,971 | $1.2 million | 0.0% | -149,542 | trimmed | 30 June 2026 | 13F |
| Two Sigma Investments | 32,925 | $476,425 | 0.0% | +16,625 | added | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| SR One Capital Management, LP | 6,526,476 | 15.07% | $94.4 million | 9.09% | no change | 13F |
| Logos Global Management LP | 3,000,000 | 6.93% | $43.4 million | 1.87% | +1,050,000 | 13F |
| Baker Bros. Advisors LP | 2,678,430 | 6.18% | $38.8 million | 0.20% | +92,452 | 13F |
| Driehaus Capital Management LLC | 2,661,115 | 6.14% | $38.5 million | 0.22% | +916,128 | 13F |
| BlackRock, Inc. | 2,660,024 | 6.14% | $38.5 million | 0.00% | +526,260 | 13F |
| Point72 Asset Management, L.P. | 2,366,453 | 5.46% | $34.2 million | 0.05% | -356,301 | 13F |
| Trails Edge Capital Partners, LP | 2,001,282 | 4.62% | $29.0 million | 4.60% | +1,149,269 | 13F |
| Frazier Life Sciences Management, L.P. | 1,809,854 | 4.18% | $26.2 million | 0.57% | new | 13F |
| Vivo Capital, LLC | 1,612,903 | 3.72% | $23.3 million | 2.13% | no change | 13F |
| Vanguard Capital Management LLC | 1,571,022 | 3.63% | $22.7 million | 0.00% | +221,172 | 13F |
| Caption Management, LLC | 1,118,098 | 2.58% | $16.2 million | 0.57% | +1,031,390 | 13F |
| Almitas Capital LLC | 1,026,893 | 2.37% | $14.9 million | 3.56% | -503,442 | 13F |
| Geode Capital Management, LLC | 958,417 | 2.21% | $13.9 million | 0.00% | +265,899 | 13F |
| Sofinnova Investments, Inc. | 865,135 | 2.00% | $12.5 million | 0.67% | new | 13F |
| FMR LLC | 776,462 | 1.79% | $11.2 million | 0.00% | -21,949 | 13F |
| Morgan Stanley | 765,425 | 1.77% | $11.1 million | 0.00% | +108,860 | 13F |
| State Street Corp. | 736,221 | 1.70% | $10.7 million | 0.00% | +76,646 | 13F |
| Woodline Partners LP | 700,354 | 1.62% | $10.1 million | 0.03% | -261,147 | 13F |
| Dimensional Fund Advisors LP | 694,743 | 1.60% | $10.1 million | 0.00% | +262,903 | 13F |
| Goldman Sachs Group Inc. | 656,584 | 1.52% | $9.5 million | 0.00% | +151,866 | 13F |
| Jacobs Levy Equity Management, Inc. | 565,597 | 1.31% | $8.2 million | 0.03% | +276,212 | 13F |
| Acadian Asset Management LLC | 537,479 | 1.24% | $7.8 million | 0.01% | -79,002 | 13F |
| Siren, L.L.C. | 523,212 | 1.21% | $7.6 million | 0.15% | new | 13F |
| Qube Research & Technologies Ltd | 437,079 | 1.01% | $6.3 million | 0.01% | +402,896 | 13F |
| Renaissance Technologies LLC | 387,913 | 0.90% | $5.6 million | 0.01% | -20,287 | 13F |
| Kennedy Capital Management LLC | 384,036 | 0.89% | $5.6 million | 0.10% | +112,482 | 13F |
| Northern Trust Corp. | 353,197 | 0.82% | $5.1 million | 0.00% | +52,918 | 13F |
| Algert Global LLC | 296,085 | 0.68% | $4.3 million | 0.05% | +91,346 | 13F |
| Acuta Capital Partners, LLC | 282,564 | 0.65% | $4.1 million | 2.85% | +136,664 | 13F |
| Charles Schwab Investment Management Inc. | 271,264 | 0.63% | $3.9 million | 0.00% | +29,779 | 13F |
| Vanguard Portfolio Management LLC | 251,442 | 0.58% | $3.6 million | 0.00% | +112,877 | 13F |
| Vanguard Fiduciary Trust Co. | 230,202 | 0.53% | $3.3 million | 0.00% | +34,544 | 13F |
| Prudential Financial Inc. | 224,170 | 0.52% | $3.2 million | 0.00% | +178,360 | 13F |
| D. E. Shaw & Co., Inc. | 195,645 | 0.45% | $2.8 million | 0.00% | -274,625 | 13F |
| Eversept Partners, LP | 190,000 | 0.44% | $2.7 million | 0.15% | new | 13F |
| KVP Capital Advisors, LP | 185,000 | 0.43% | $2.7 million | 1.97% | new | 13F |
| J. Goldman & Co LP | 176,770 | 0.41% | $2.6 million | 0.09% | new | 13F |
| Millennium Management LLC | 147,714 | 0.34% | $2.1 million | 0.00% | +38,786 | 13F |
| Raymond James Financial Inc. | 138,521 | 0.32% | $2.0 million | 0.00% | +30,072 | 13F |
| Balyasny Asset Management L.P. | 111,103 | 0.26% | $1.6 million | 0.00% | new | 13F |
| Elmind Capital, LP | 107,900 | 0.25% | $1.6 million | 0.39% | -100,000 | 13F |
| Nuveen, LLC | 104,734 | 0.24% | $1.5 million | 0.00% | -22,081 | 13F |
| Dafna Capital Management LLC | 102,600 | 0.24% | $1.5 million | 0.28% | new | 13F |
| Bank of New York Mellon Corp | 92,069 | 0.21% | $1.3 million | 0.00% | +12,424 | 13F |
| China Universal Asset Management Co., Ltd. | 89,940 | 0.21% | $1.3 million | 0.08% | +54,831 | 13F |
| Citadel Advisors LLC | 81,971 | 0.19% | $1.2 million | 0.00% | -149,542 | 13F |
| SummitTX Capital, L.P. | 80,663 | 0.19% | $1.2 million | 0.03% | new | 13F |
| American Century Companies Inc. | 76,825 | 0.18% | $1.1 million | 0.00% | +11,187 | 13F |
| Palumbo Wealth Management LLC | 71,744 | 0.17% | $1.0 million | 0.22% | +336 | 13F |
| AQR Capital Management LLC | 71,114 | 0.16% | $1.0 million | 0.00% | +45,157 | 13F |
The 50 largest of the 136 funds that reported a position in DSGN in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on DSGN
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 13,900 | $201,133 | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 14 August 2026 | 13G/A | Point72 Asset Management, L.P. and 5 others | 2.4 million | 3.8% | 30 June 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 August 2026 | 13G | Sirenia Capital Management LP and 3 others | 6.0 million | 9.5% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 9 June 2026 | 13G | Point72 Asset Management, L.P. and 5 others | 3.2 million | 5.1% | 8 June 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 15 May 2026 | 13G/A | Point72 Asset Management, L.P. and 5 others | 2.7 million | 4.4% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 11 March 2026 | 13D/A | SR One Capital Fund I Aggregator, LP and 3 others | 6.6 million | 10.7% | 9 March 2026 | Not applicable. | EDGAR |
| 17 February 2026 | 13G/A | Point72 Asset Management, L.P. and 5 others | 5.4 million | 9.4% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 18 November 2025 | 13D/A | Logos Global Management LP and 4 others | 2.5 million | 4.4% | 14 November 2025 | The reporting persons filed this Schedule 13D because Dr. William was on the Issuer' board of directors. Dr. William resigned from the Issuer's board of directors on September 9, 2025. The reporting persons will routinely monitor the Issuer | EDGAR |
| 12 November 2025 | 13D/A | Logos Global Management LP and 4 others | 3.3 million | 5.7% | 7 November 2025 | The reporting persons filed this Schedule 13D because Dr. William was on the Issuer's board of directors. Dr. William has resigned from the Issuer's board of directors on September 9, 2025. The reporting persons will routinely monitor the I | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 30 September 2026 | 884 | $12.62 | SEC |
| 24 September 2026 | 305 | $12.36 | SEC |
| 22 September 2026 | 317 | $12.55 | SEC |
| 4 September 2026 | 9 | $15.03 | SEC |
| 2 September 2026 | 335 | $15.14 | SEC |
| 1 September 2026 | 638 | $15.09 | SEC |
| 26 August 2026 | 6,929 | $15.68 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.