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Adma Biologics, Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 25 February 2026: press release. Guidance figures: 2 raised, 7 kept. The quarter’s numbers.

Key takeaways

  • Full-year revenue rose 20%: Full-year 2025 revenue reached $510.2 million, up $83.7 million or 20%. Excluding a 2024 Medicaid rebate accrual adjustment, growth was about 23%. Source
  • Adjusted EBITDA rose 40%: Full-year adjusted EBITDA reached $231.0 million, up 40%. Full-year adjusted net income was $160.8 million, up 35%. Source
  • ASCENIV sales rose 51%: ASCENIV revenue was $362.5 million for 2025, up 51%. Management tied growth to demand, prescriber adoption and record utilization exiting the year. Source
  • Full-year gross margin rose to 57.4%: Full-year gross margin was 57.4% against 51.5%, and fourth-quarter corporate gross margin was 63.8%. Full-year gross profit was $292.8 million. Source
  • Three plasma centers to be sold: ADMA agreed in December 2025 to divest three plasma centers for $12 million and keep seven centers, with long-term supply agreements with the buyer. Source
  • Year-end cash about $88 million: Cash was about $88 million at year end, largely excluding plasma divestiture proceeds. The balance sheet shows $87.6 million, down from $103.1 million. Source
  • SG-001 preclinical work advanced: SG-001 preclinical development advanced in 2025, and a pre-IND package is planned for submission to the FDA in 2026. Source

“2025 marked a year of disciplined execution, record performance and meaningful strategic progress for ADMA, and we are entering 2026 with significant momentum,”

Adam Grossman, President and Chief Executive Officer of ADMA

Guidance

AreaPeriodFigureAgainst last quarter
Total revenue SourceFY 2026exceed $635 millionRaised from $630 million
Adjusted Net Income SourceFY 2026exceed $255 millionKept
Adjusted EBITDA SourceFY 2026exceed $360 millionRaised from $355 million
Total revenue SourceFY 2027exceed $775 millionKept
Adjusted Net Income SourceFY 2027exceed $315 millionKept
Adjusted EBITDA SourceFY 2027exceed $455 millionKept
Total annual revenue target SourceFY 2029greater than $1.1 billionKept
Adjusted EBITDA target SourceFY 2029at least $700 millionKept
SG-001 peak annual revenue Sourcelong term (peak)$300 - $500 millionKept

What changed from last quarter

  • Guidance raised: FY 2026 total revenue guidance increased to approximately $635 million from $630 million.
  • Guidance raised: FY 2026 Adjusted EBITDA guidance increased to approximately $360 million from $355 million.
  • Guidance kept: FY 2026 Adjusted Net Income guidance was reiterated at approximately $255 million.
  • Guidance kept: The fiscal 2029 targets of more than $1.1 billion in revenue and at least $700 million in Adjusted EBITDA were restated. Source
  • New: Terry Kohler was appointed Chief Financial Officer and Treasurer, succeeding Brad Tade, who retired. Source
  • New: The company said direct-to-patient initiatives had recently commenced, alongside field execution and medical education. Source

Full-year and fourth-quarter results

  • Full-year revenue rose 20%: Full-year 2025 revenue reached $510.2 million, up $83.7 million or 20%. Excluding a 2024 Medicaid rebate accrual adjustment, growth was about 23%. Source
  • Fourth-quarter revenue rose 18%: Fourth-quarter revenue was $139.2 million, up 18% year over year. Fourth-quarter gross profit rose 40% to $88.8 million. Source
  • Adjusted EBITDA rose 40%: Full-year adjusted EBITDA reached $231.0 million, up 40%. Full-year adjusted net income was $160.8 million, up 35%. Source
  • Fourth-quarter GAAP net income fell: Fourth-quarter GAAP net income was $49.4 million, against $111.9 million a year earlier, when a $84.3 million tax benefit was recognized. Source
  • Diluted EPS declined year over year: Diluted EPS was $0.60 for full year 2025 against $0.81 in 2024, and $0.20 for the fourth quarter against $0.46. Source

ASCENIV and other product sales

  • ASCENIV sales rose 51%: ASCENIV revenue was $362.5 million for 2025, up 51%. Management tied growth to demand, prescriber adoption and record utilization exiting the year. Source
  • BIVIGAM and intermediates declined: BIVIGAM sales fell 14% to $122.0 million. Intermediates and other products fell 75% to $8.6 million. Source
  • Plasma collection revenue rose 62%: Plasma collection center revenue was $17.0 million, up 62% from $10.5 million in 2024. Source

“Yield-enhanced production is now fully integrated into commercial operations, our plasma collection network has been strategically repositioned to improve margins and working capital efficiency, and our balance sheet continues to strengthen.”

Adam Grossman, President and Chief Executive Officer of ADMA

Margins and cost lines

  • Full-year gross margin rose to 57.4%: Full-year gross margin was 57.4% against 51.5%, and fourth-quarter corporate gross margin was 63.8%. Full-year gross profit was $292.8 million. Source
  • Yield-enhanced production drives 2026 margins: Management described 2026 as the first full year of yield-enhanced output, which it expects to support sustained gross margin growth. Source
  • SG&A rose on compensation and insurance: SG&A reached $91.6 million, up from $74.1 million, mainly on higher compensation for business and manufacturing growth, plus insurance premiums, professional fees and software. Source
  • R&D rose on SG-001 spending: R&D expense was $4.8 million for 2025, against $1.8 million in 2024, reflecting investment in SG-001. Source

Demand, payers and distribution

  • Payer coverage broadened across channels: Management described broad and improving payer coverage for ASCENIV and BIVIGAM across commercial plans and Medicare Part B, supporting consistent patient access. Source
  • McKesson Specialty distribution agreement signed: A new authorized distribution agreement with McKesson Specialty covers ASCENIV and BIVIGAM and is expected to open more sites of care and patient populations. Source
  • Distribution expected to aid receivables: Management expects the expanded distribution platform to improve accounts receivable performance and cash conversion as the partnership ramps up. Source

“we are confident in our ability to generate operating leverage and execute against both our near- and long-term targets”

Adam Grossman, President and Chief Executive Officer of ADMA

Plasma network repositioning

  • Three plasma centers to be sold: ADMA agreed in December 2025 to divest three plasma centers for $12 million and keep seven centers, with long-term supply agreements with the buyer. Source
  • Third-party plasma suppliers exceeded expectations: Third-party suppliers exceeded expectations in 2025, and new contracts give access to more than 280 plasma collection centers. Source
  • Plasma actions expected to cut costs: Management expects the plasma actions to deliver accretive cost savings beginning in 2026 and to support supply through the late 2030s and beyond. Source

Cash, balance sheet and capital

  • Year-end cash about $88 million: Cash was about $88 million at year end, largely excluding plasma divestiture proceeds. The balance sheet shows $87.6 million, down from $103.1 million. Source
  • Treasury stock held at $32.1 million: Treasury stock at cost was $32.1 million for 1,919,070 shares at year end, against none a year earlier, as the company reports ongoing share repurchases. Source
  • Long-term debt declined modestly: Long-term debt was $69.3 million at year end, against $72.3 million a year earlier. Source

Pipeline and SG-001

  • SG-001 preclinical work advanced: SG-001 preclinical development advanced in 2025, and a pre-IND package is planned for submission to the FDA in 2026. Source
  • Broad serotype coverage targeted: The company said SG-001 is designed for broad pneumococcal serotype coverage, including prevalent and emerging serotypes not fully covered by current vaccines. Source
  • Pre-IND package could enable registrational path: The company said the pre-IND package could potentially enable direct progression into a registrational trial, which the release describes as an accelerated path. Source

Leadership transition

  • Kohler's prior CFO roles: Kohler most recently served as CFO of OptiNose, through its acquisition by Paratek, and earlier as CFO of Verrica Pharmaceuticals. Source
  • Tade consulting through July 2026: Brad Tade will serve in a consulting capacity to support the transition through July 2026. Source
  • Tade retirement after tenure: Brad Tade retires as CFO and Treasurer; the company credits his tenure with its move to sustained profitability. Source

Clinical evidence for ASCENIV

  • Peer-reviewed study supports ASCENIV: A peer-reviewed study by Tan et al. reported reductions in infections and hospitalizations in patients who switched to ASCENIV after failing prior IVIG. Source
  • 71% of patients improved clinically: In that study, 71% of patients improved clinically, with the greatest impact in the first six months of treatment. Source
  • Investigator analyses show infection reductions: Investigator-initiated analyses reported statistically significant infection reductions, which the company says support payer engagement and medical education. Source

Coming up, as management said on 25 February 2026

  • Cash generation expected through 2026: Management expects cost savings, improved financial flexibility and stockholder returns to support growth and balance sheet work during 2026. Source
  • Distribution diversification continues in 2026: Management said constructive discussions continue to further diversify distribution in 2026, supporting product growth and operational efficiency. Source

Figures management reported

FigureReported
ASCENIV product revenue, FY 2025 Source$362.5 million
BIVIGAM product revenue, FY 2025 Source$122.0 million
Plasma collection center revenue, FY 2025 Source$17.0 million
Gross margin, FY 2025 Source57.4%
Corporate gross margin, fourth quarter 2025 Source63.8%
R&D expense, FY 2025 Source$4.8 million
Patients improved clinically in peer-reviewed study Source71%

Risks management discussed

  • Operational: Voluntary withdrawal and product replacement costs were $6.2 million for the year and were excluded from Adjusted EBITDA. Source
  • Operational: Management cites confidence in long-term supply continuity as one of the drivers of ASCENIV growth into 2026. Source

Earlier plans management reported on

  • On track: Management said the transaction remains on track to close in the first quarter of 2026. Source
  • Met: Yield-enhanced production moved into routine commercial execution in 2025, with continued FDA lot releases. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.