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Acadia Pharmaceuticals (ACAD) FY2025 results: revenue $1.1 billion, up 11.9% on the year

Acadia Pharmaceuticals Inc. (ACAD) reported revenue of $1.1 billion for fiscal 2025, the year ended 31 December 2025, up 11.9% on the year before. Net income was $391 million, up 72.7%, and diluted earnings per share $2.30. The figures are the company's own, from the 10-K it filed with the SEC on 26 February 2026.

Revenue
$1.1 billion
+11.9% on the year
FY2018FY2025
Operating margin
9.8%
24.1% a year earlier
FY2018FY2025
Net income
$391 million
+72.7% on the year
FY2018FY2025
Diluted EPS
$2.30
+69.1% on the year
FY2018FY2025

this yearthe year beforeHover a bar for its figure.

The year in brief

What management said about the year

  • Revenue grew on GAAP and adjusted bases: GAAP total revenues were $284 million in the fourth quarter of 2025, up 9%, and $1.07 billion for the full year, up 12%. Non-GAAP adjusted total revenues were $298 million for the quarter, up 16%, and $1.08 billion for the year, up 14%.
  • NUPLAZID adjusted quarterly sales rose 17%: Non-GAAP adjusted NUPLAZID net sales were $189 million in the fourth quarter, up 17% from $161 million. GAAP net sales for the quarter were $174 million.
  • Volume rose 9% for year, 13% in quarter: NUPLAZID volume grew 9% over the full year 2025 and 13% in the fourth quarter. The company stated the GAAP accounting adjustment does not reflect this underlying commercial performance.
  • IRA rebate estimate raised $20 million: The company recorded a $20 million change in estimate to NUPLAZID IRA rebate accruals covering sales from 2022 through 2025, after first IRA invoices came in above expectations. Non-GAAP figures reallocate this amount to the years the sales were earned.
  • DAYBUE quarterly sales rose 13%: DAYBUE net product sales were $110 million in the fourth quarter, up 13% from $97 million, mainly due to growth in unit sales.
Read the Q4 FY2025 earnings call summary

The four quarters: Q1 FY2025 · Q2 FY2025 · Q3 FY2025 · Q4 FY2025

Income statement (profit and loss)

$ millionFY2025FY2024FY2023On the yearLast 8 years
Revenue1,072958726+11.9%
Cost of revenue89.081.841.6+8.7%
Gross profit983876685+12.2%
Gross margin91.7%91.5%94.3%
Research and development329303352+8.4%
Selling, general and administrative549488407+12.4%
Operating income105231-73.4-54.6%
Operating margin9.8%24.1%-10.1%
Pre-tax income139258-51.0-46.2%
Income tax-25231.610.2
Effective tax rate-181.5%12.3%n/a
Net income391226-61.3+72.7%
Net margin36.5%23.6%-8.4%
Diluted EPS$2.30$1.36-$0.37+69.1%
$ million except per share.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow

$ millionFY2025FY2024FY2023On the yearLast 8 years
Operating cash flow11015816.7-30.4%
Capital expenditure4.70.50.1+796.7%
Free cash flow10515716.7-33.1%
Free cash flow margin9.8%16.4%2.3%
Cash from investing-303-30.532.0
Cash from financing49.96.825.1+628.8%
Depreciation and amortisation11.815.95.6-26.0%
Share-based compensation52.167.066.4-22.2%
Diluted shares, weighted170m166m164m+2.1%
Shares outstanding at period end170m167m165m+2.2%

Balance sheet

$ millionFY2025FY2024FY2023On the yearLast 8 years
Shareholders' equity1,227733432+67.5%
Debt0.00.00.0
Operating lease liabilities40.642.047.8-3.5%
Other liabilities296413269-28.3%
Total liabilities and equity1,5641,188749+31.7%
Fixed assets7.54.24.6+78.2%
Intangible assets10912065.5-9.1%
Investments642436250+47.1%
Cash and equivalents178320189-44.4%
Receivables12198.798.3+23.0%
Inventory11191.740.4+21.5%
Other assets395117101+236.9%
Total assets1,5641,188749+31.7%

10-K for the year ended 31 December 2025, filed 26 February 2026: the filing.