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Xenon Pharmaceuticals Inc. 13F holders

315 funds reported a position in Xenon Pharmaceuticals Inc. in their 13F for the quarter ended 30 June 2026, together 101.1 million shares worth $6.10 billion. Against the quarter before, 42 opened a position, 126 added, 86 trimmed and 22 sold out; together they bought a net 712,529 shares. The largest holders: FMR LLC, BlackRock, Inc. and Avoro Capital Advisors LLC.

Funds holding315+25 on Q1 2026
Shares they held101.1Mworth $6.10 billion
Net bought on the quarter712,529 sharesabout $43.0 million at the funds' values
Funds buying to selling168 to 108opened or added, to cut or sold
Opened 42Added 126Held 59Trimmed 86Sold out 22
Opened: 42 fundsAdded: 126 fundsHeld: 59 fundsTrimmed: 86 fundsSold out: 22 funds

What each fund did in XENE against its 13F for the quarter before; a change under 0.1% of a holding counts as held

Q3 2024: 203 funds, 75.9 million shares203Q3 2024Q4 2024: 209 funds, 76.3 million shares209Q4 2024Q1 2025: 206 funds, 76.8 million shares206Q1 2025Q2 2025: 206 funds, 83.3 million shares206Q2 2025Q3 2025: 219 funds, 85.7 million shares219Q3 2025Q4 2025: 246 funds, 84.6 million shares246Q4 2025Q1 2026: 290 funds, 100.4 million shares290Q1 2026Q2 2026: 315 funds, 101.1 million shares315Q2 2026

Funds reporting a position in XENE in their 13F, each quarter; hover a bar for the shares they held

Filed so far for the quarter to 30 September 2026

2,671 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 27 reported a position in Xenon Pharmaceuticals Inc.: 3 opened one, 11 added, 7 trimmed and 7 sold out, a net 71,286 shares bought.

FundChange in sharesShares nowStatusFiling
Y-Intercept (Hong Kong) Ltd+57,97357,973new13F
J. Safra Sarasin Holding AG+15,26033,010added13F
Wedmont Private Capital+11,27511,275new13F
Elmwood Wealth Management, Inc.+3,76013,577added13F
Sterling Capital Management LLC+2,8943,239added13F
Assetmark, Inc.-2,38216,952trimmed13F
Mutual of America Capital Management LLC-1,009108,594trimmed13F
KBC Group NV+599129,609added13F
Nisa Investment Advisors, LLC+4672,297added13F
GF Fund Management Co. Ltd+4162,179added13F
Gamma Investing LLC+312830added13F
Farther Finance Advisors, LLC-12096trimmed13F
IFP Advisors, Inc+661,937added13F
SBI Securities Co., Ltd.+481,036added13F
Mather Group, LLC.+3434new13F
SJS Investment Consulting Inc.-307trimmed13F
Physician Wealth Advisors, Inc.+2134added13F
Signaturefd, LLC-21739trimmed13F
CoreCap Advisors, LLC-1317trimmed13F
First Horizon Corp.-817trimmed13F
MassMutual Private Wealth & Trust, FSB+118added13F
Abel Hall, LLC-3,8090sold out13F
Ares Financial Consulting, LLC-120sold out13F
Blue Trust, Inc.-7240sold out13F
Citizens Financial Group Inc.-5,2910sold out13F

The largest moves in the name among the funds that have filed, against each fund's previous 13F.

The well-known funds

Of the 44 funds followed here, 9 reported a position in Xenon Pharmaceuticals Inc. in a 13F for the quarter ended 30 June 2026. The largest: FMR LLC, 9.6 million shares worth $582.4 million, 0.0% of its reported book. New this quarter: Point72 Asset Management. In the quarter, 4 funds added or opened a position and 4 trimmed or sold out; together they sold a net 1.5 million shares, about $91.6 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.

FundSharesValueOf its bookChange on the quarterStatusQuarter endedFiling
FMR LLC9,647,998$582.4 million0.0%-1,170,493trimmed30 June 202613F
Two Sigma Investments1,642,848$99.2 million0.1%+1,036,763added30 June 202613F
Citadel Advisors1,401,242$84.6 million0.0%-1,251,748trimmed30 June 202613F
Geode Capital Management1,370,114$82.7 million0.0%+277,182added30 June 202613F
Alyeska697,692$42.1 million0.1%-601,777trimmed30 June 202613F
Millennium Management376,777$22.7 million0.0%+174,992added30 June 202613F
Duquesne Family Office238,600$14.4 million0.3%no changeheld30 June 202613F
Renaissance Technologies187,110$11.3 million0.0%-113,390trimmed30 June 202613F
Point72 Asset Management130,378$7.9 million0.0%+130,378new30 June 202613F
Value is what the fund reported.
Read moreChange is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.

The largest holders

FundSharesShare of allValueOf its bookChange in sharesFiling
FMR LLC9,647,9989.54%$582.4 million0.03%-1,170,49313F
BlackRock, Inc.7,522,4827.44%$454.1 million0.01%+1,882,36413F
Avoro Capital Advisors LLC5,777,7775.71%$348.7 million3.13%no change13F
Polar Capital Holdings Plc4,570,5564.52%$275.9 million0.78%+165,24413F
Driehaus Capital Management LLC4,418,5574.37%$266.7 million1.55%-73,09613F
Jupiter Topco LLC4,186,5194.14%$252.7 million0.10%first 13F13F
Price T Rowe Associates Inc.3,248,2193.21%$196.1 million0.02%+1,918,62813F
JPMorgan Chase & Co.2,617,3602.59%$157.4 million0.01%+693,75013F
Capital International Investors2,361,6392.34%$142.5 million0.03%-313,08813F
T. Rowe Price Investment Management, Inc.2,168,5812.14%$130.9 million0.09%+1,216,62613F
State Street Corp.1,969,6291.95%$118.9 million0.00%+249,09613F
Two Sigma Investments, LP1,642,8481.62%$99.2 million0.08%+1,036,76313F
Deerfield Management Company, L.P.1,615,6961.60%$97.5 million1.21%no change13F
Affinity Asset Advisors, LLC1,595,0001.58%$96.3 million4.77%-80,00013F
Westfield Capital Management Co. LP1,507,2941.49%$91.0 million0.30%+105,81113F
AllianceBernstein L.P.1,562,2761.55%$90.8 million0.03%+158,97913F
Franklin Resources Inc.1,437,7121.42%$86.8 million0.02%+157,13513F
Wellington Management Group LLP1,425,4921.41%$86.0 million0.01%-3,404,14913F
Citadel Advisors LLC1,401,2421.39%$84.6 million0.05%-1,251,74813F
Geode Capital Management, LLC1,370,1141.36%$82.7 million0.00%+277,18213F
Siren, L.L.C.1,318,5641.30%$79.6 million1.62%no change13F
BNP Paribas Asset Management Holding S.A.1,290,7311.28%$77.9 million0.08%-51,29713F
Pictet Asset Management Holding SA1,187,7231.17%$71.6 million0.07%+508,01413F
Braidwell LP1,131,4521.12%$68.3 million2.62%-207,00013F
Nuveen, LLC993,1260.98%$59.9 million0.01%+743,09013F
Invesco Ltd.903,4580.89%$54.5 million0.00%+844,35513F
Orbimed Advisors LLC892,4710.88%$53.9 million1.02%-167,50013F
Caligan Partners LP889,9440.88%$53.7 million2.59%-503,08313F
American Century Companies Inc.884,3190.87%$53.4 million0.02%+205,00513F
Federated Hermes, Inc.883,7370.87%$53.3 million0.08%-88,50013F
Capital World Investors862,7750.85%$52.1 million0.01%+22,70313F
Goldman Sachs Group Inc.773,6250.77%$46.7 million0.01%+3,75013F
Vanguard Portfolio Management LLC749,6510.74%$45.2 million0.00%+206,58913F
Vestal Point Capital, LP700,0000.69%$42.3 million0.99%+60,10013F
Alyeska Investment Group, L.P.697,6920.69%$42.1 million0.11%-601,77713F
Marshall Wace, LLP689,3420.68%$41.6 million0.04%new13F
Rock Springs Capital Management LP683,9070.68%$41.3 million2.02%-79,11313F
Northern Trust Corp.671,5660.66%$40.5 million0.01%+143,78313F
Panagora Asset Management Inc.664,0310.66%$40.1 million0.12%new13F
First Turn Management, LLC600,2000.59%$36.2 million3.88%-186,64413F
Tudor Investment Corp. Et Al545,3870.54%$32.9 million0.14%+49,79613F
Loomis Sayles & Co. L P527,2730.52%$31.8 million0.04%-37,62413F
Octagon Capital Advisors LP490,0000.48%$29.6 million2.71%no change13F
Novo Holdings A/s485,4380.48%$29.3 million1.70%no change13F
Candriam S.C.A.462,7680.46%$27.9 million0.13%-13,72613F
TimesSquare Capital Management, LLC451,5930.45%$27.3 million0.40%+92,30013F
Logos Global Management LP450,0000.45%$27.2 million1.17%no change13F
Trails Edge Capital Partners, LP440,0000.44%$26.6 million4.22%no change13F
Bank of New York Mellon Corp421,5180.42%$25.4 million0.00%+25,38013F
Algert Global LLC419,7730.42%$25.3 million0.30%+155,57313F
The 50 largest of the 315 funds that reported a position in XENE in their 13F for the quarter ended 30 June 2026, by the value each reported.
Read moreShare of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?

Options the funds reported on XENE

FundOptionShares under the optionsValue of those sharesQuarter endedFiling
Citadel AdvisorsCalls38,400$2.3 million30 June 202613F
Citadel AdvisorsPuts8,500$513,06030 June 202613F
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
Read moreThey are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.

Schedule 13D and 13G filed on the name, last twelve months

FiledScheduleWhoHoldingOf the classEvent dateRule or purposeFiling
13 August 202613G/AWellington Management Group LLP and 5 others1.4 million1.5%30 June 2026passive, institutional (13d-1(b))EDGAR
7 August 202613G/AFMR LLC and 3 others10.0 million10.3%31 July 2026passive, institutional (13d-1(b))EDGAR
6 August 202613G/AFMR LLC and 3 others9.6 million9.9%30 June 2026passive, institutional (13d-1(b))EDGAR
15 May 202613G/AJanus Henderson Group PLC and 1 other4.2 million4.5%31 March 2026passive, institutional (13d-1(b))EDGAR
15 May 202613G/ADriehaus Capital Management LLC and 1 other4.5 million4.9%31 December 2025passive, institutional (13d-1(b))EDGAR
15 May 202613G/AAvoro Capital Advisors LLC and 3 others5.8 million6.3%31 March 2026passive, institutional (13d-1(b))EDGAR
10 February 202613GWellington Management Group LLP and 7 others4.8 million6.2%31 December 2025passive, institutional (13d-1(b))EDGAR
14 November 202513GJanus Henderson Group PLC and 1 other3.9 million5.1%30 September 2025passive, institutional (13d-1(b))EDGAR
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
Read moreAmendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13G

Fails to deliver

Settlement dateShares failedPriceFile
1 September 2026671$60.22SEC
24 August 202616$60.77SEC
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.
Read moreLargest in the window: 671 on 1 September 2026. A fail is an operational fact about settlement, not a position.