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Viatris Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 26 February 2026: press release. Guidance figures: 15 new. The quarter’s numbers.

Key takeaways

  • Fourth-quarter revenue rose 5%: Total revenues were $3.7 billion, up 5% reported and up 2% on a divestiture-adjusted operational basis versus fourth-quarter 2024. Source
  • Fourth-quarter loss tied to plants: The company attributed the fourth-quarter U.S. GAAP net loss of $(340) million mainly to contractual termination costs, remediation costs and manufacturing variances at plants slated for sale or closure. Source
  • Adjusted EPS up 6% in quarter: Adjusted EPS was $0.57 in the fourth quarter, up 6% reported, and adjusted EBITDA was $1.0 billion, up 2% reported. The company attributed both mainly to brands performance. Source
  • New product revenue reached $324 million: New product revenues were about $78 million in the fourth quarter and about $324 million for 2025, the company said. Source
  • Restructuring spans commercial and supply: Restructuring is expected to optimize commercial capabilities, enabling functions, R&D, medical affairs, regulatory activities, and sourcing and supply chain, including inventory. Source
  • Free cash flow excluding transaction costs $2.2B: Operating cash flow was $2.3 billion for 2025, and free cash flow excluding transaction costs was $2.2 billion. Source
  • Nashik shutdown included in guidance: The company said it considered the Nashik fire and facility shutdown when formulating its 2026 financial guidance. Source

“2025 was a year of strong execution across our global business, and we enter 2026 from a position of strength,”

Scott A. Smith, CEO, Viatris

Guidance

AreaPeriodFigureAgainst last quarter
Total revenues Sourcefiscal year 2026$14,450 - $14,950 million (midpoint $14,700 million)New
Adjusted EBITDA Sourcefiscal year 2026$4,150 - $4,450 million (midpoint $4,300 million)New
Adjusted EPS Sourcefiscal year 2026$2.33 - $2.47 (midpoint $2.40)New
Free cash flow excluding transaction and restructuring costs Sourcefiscal year 2026$1,950 - $2,350 million (midpoint $2,150 million)New
U.S. GAAP net cash provided by operating activities Sourcefiscal year 2026$1.7 billion - $2.0 billion (midpoint approximately $1.85 billion)New
Capital expenditures Sourcefiscal year 2026$350 - $450 millionNew
Free cash flow (reported basis) Sourcefiscal year 2026$1,250 - $1,650 millionNew
Transaction- and restructuring-related costs in free cash flow bridge Sourcefiscal year 2026approximately $700 millionNew
New product revenues Sourcefiscal year 2026$450 million - $550 millionNew
Restructuring pre-tax charges Sourcecommitted restructuring activities of the enterprise-wide strategic review$700 million - $850 million total, including $50 million - $100 million non-cashNew
Restructuring savings Sourceonce fully implemented$600 million - $700 millionNew
Total cost savings Sourceover the next 3 years$650MNew
Reinvestment of savings Sourceover the next 3 yearsup to $250MNew
Global workforce reduction Sourcerestructuring activities, primarily over the next three yearsup to approximately 10%New
Exchange rates used for 2026 guidance Sourcefiscal year 2026CNY 7.19; EUR 0.87; INR 85.80; JPY 144.35 (per US dollar as the release presents them)New

What changed from last quarter

  • New guidance: The company provided 2026 financial guidance for total revenues, adjusted EBITDA, adjusted EPS and free cash flow. Source
  • New: The enterprise-wide strategic review concluded, and the company began committed restructuring activities. Source
  • Ended: Viatris sold its convertible preferred equity stake in Biocon Biologics to Biocon for $815 million, and the transaction closed in the first quarter of 2026. Source
  • New: A fire occurred in mid-February 2026 in a service area at the Nashik, India oral solid dose plant, and manufacturing there was suspended. Source
  • New: The FDA accepted the sNDA for MR-141 for presbyopia and assigned a PDUFA goal date of October 17, 2026. Source
  • New: The FDA accepted the NDA for the low-dose estrogen weekly patch for contraception and set a PDUFA goal date of July 30, 2026. Source
  • New: The FDA approved a generic version of Sandostatin LAR Depot, octreotide acetate for injectable suspension, in December 2025. Source
  • New: Inpefa (sotagliflozin) launched in the United Arab Emirates in January 2026, the first country in Viatris' current operations to commercialize it. Source
  • New: The FDA cleared the IND application for MR-146, an AAV gene therapy candidate for neurotrophic keratopathy, in December 2025. Source
  • New: The company had been on track to submit a Japanese NDA for pitolisant in narcolepsy by end-2025, and both pitolisant J-NDAs are now under review by PMDA. Source

Fourth-quarter and full-year results

  • Fourth-quarter revenue rose 5%: Total revenues were $3.7 billion, up 5% reported and up 2% on a divestiture-adjusted operational basis versus fourth-quarter 2024. Source
  • Full-year revenue fell 3%: Full-year total revenues were $14.3 billion, down 3% reported and down 1% on a divestiture-adjusted operational basis, from $14.7 billion in 2024. Source
  • Full-year net loss includes goodwill charge: The 2025 U.S. GAAP net loss was $(3,514.9) million, including a $2.9 billion goodwill impairment charge from the interim test as of March 31, 2025. Source
  • Fourth-quarter loss tied to plants: The company attributed the fourth-quarter U.S. GAAP net loss of $(340) million mainly to contractual termination costs, remediation costs and manufacturing variances at plants slated for sale or closure. Source
  • Adjusted EPS up 6% in quarter: Adjusted EPS was $0.57 in the fourth quarter, up 6% reported, and adjusted EBITDA was $1.0 billion, up 2% reported. The company attributed both mainly to brands performance. Source

Segments, regions and product categories

  • Greater China and Emerging Markets grew: Brands net sales grew in Greater China and Emerging Markets in the fourth quarter, with certain key brands also growing in Developed Markets. Source
  • Generics hit by North America competition: Fourth-quarter Generics net sales were affected by expected competition on certain North American products and by Japanese government price regulation. Source
  • Full-year Brands flat, Generics down 8%: For 2025, Brands net sales were $9.2 billion, flat reported and up 3% divestiture-adjusted, while Generics net sales fell 8% reported to $5.1 billion. Source
  • Developed Markets and Emerging Markets fell: Full-year Developed Markets net sales fell 5% reported to $8.5 billion, and Emerging Markets net sales fell 2% reported to $2.2 billion. Source

“Today marks an important inflection point in Viatris’ evolution.”

Scott A. Smith, CEO, Viatris

Products and pipeline

  • New product revenue reached $324 million: New product revenues were about $78 million in the fourth quarter and about $324 million for 2025, the company said. Source
  • Six regulatory decisions expected in 2026: Management anticipates regulatory decisions for six product candidates in 2026, along with multiple important pipeline milestones. Source
  • EpiPen sales rose sharply: EpiPen Auto-Injectors net sales were $79.0 million in the fourth quarter and $469.7 million for 2025, against $73.1 million and $392.0 million a year earlier. Source

Restructuring and cost actions

  • Restructuring spans commercial and supply: Restructuring is expected to optimize commercial capabilities, enabling functions, R&D, medical affairs, regulatory activities, and sourcing and supply chain, including inventory. Source
  • Most savings to lift operating cash flow: Most of the expected savings are expected to improve operating cash flow, the company said. Source
  • Remaining cash costs mainly severance: Remaining restructuring cash costs of $650 million to $750 million are expected to be primarily severance and employee benefits expense. Source

“Our strong performance for the fourth quarter and full year reflect our continued disciplined execution as we delivered on our 2025 financial commitments.”

Doretta Mistras, CFO, Viatris

Margins and cash generation

  • Fourth-quarter adjusted gross margin rose: Adjusted gross margin was 56.8% in the fourth quarter, up from 56.3% a year earlier, on adjusted gross profit of $2.1 billion. Source
  • Full-year adjusted gross margin fell: Adjusted gross margin was 56.3% for 2025, down from 57.9% in 2024, on adjusted gross profit of $8.1 billion. Source
  • Free cash flow excluding transaction costs $2.2B: Operating cash flow was $2.3 billion for 2025, and free cash flow excluding transaction costs was $2.2 billion. Source
  • Full-year capital spending rose 16%: Capital expenditures were $378.8 million for 2025, up 16% from $326.0 million in 2024. Source

Capital and shareholder returns

  • Over $1 billion returned in 2025: The company returned more than $1 billion to shareholders in 2025 and expects a balanced capital allocation approach for 2026. Source
  • Cash for deployment in 2026: Management expects significant cash to be available for deployment under its balanced capital allocation framework. Source
  • Dividends and buybacks through year-to-date: In the third-quarter release, the company said it had returned more than $920 million year-to-date, including $500 million in share repurchases.

Manufacturing and 2026 guidance basis

  • Indore impact on 2025 revenue: The company estimated the Indore Impact on 2025 total revenues at approximately $370 million. Source
  • Nashik shutdown included in guidance: The company said it considered the Nashik fire and facility shutdown when formulating its 2026 financial guidance. Source
  • Unsigned-deal IPR&D excluded from guidance: 2026 guidance excludes acquired IPR&D for unsigned deals, which the company said cannot be reasonably forecast. Source
  • No GAAP net or EPS guidance given: The company gave no forward-looking U.S. GAAP net earnings or diluted EPS guidance, citing items it cannot predict with reasonable certainty. Source

Coming up, as management said on 26 February 2026

  • Investor Event set for March 19: Executives will outline long-term revenue and earnings growth, portfolio strategy, R&D capabilities and pipeline programs at an investor event. Source
  • Nashik plant to resume in April: Manufacturing at the Nashik facility is suspended, and the company currently expects to resume operations beginning in April 2026. Source
  • Restructuring to finish over three years: The company expects the restructuring activities, with associated costs and savings, to be completed primarily over the next three years. Source
  • Inpefa launches planned in more countries: Further Inpefa launches are planned in multiple countries over the next several years, beyond the United Arab Emirates launch. Source

In management's words

“In 2026, we anticipate continued operational growth driven by our base business and net cost savings.”

Doretta Mistras, CFO, Viatris

Figures management reported

FigureReported
Product sales: Lipitor Source$377.3 million in Q4 2025; $1,549.3 million for 2025
R&D spend (U.S. GAAP) Source$965.9 million for 2025; $274.7 million in Q4 2025
IPR&D impairment after clinical results Source$71.7 million in Q4 2025; $73.9 million for 2025

Risks management discussed

  • Operational: A February 2026 fire at the Nashik oral solid dose facility led to a temporary manufacturing suspension. Source
  • Regulatory: The Indore impact reflects supply disruptions and an FDA warning letter and import alert on the Indore oral finished dose facility. Source
  • Demand: Expected competition on certain North American generic products reduced fourth-quarter Generics net sales. Source
  • Regulatory: Government price regulation in Japan had a negative effect on fourth-quarter sales. Source
  • Financial: Fair-value remeasurement of Biocon Biologics preferred shares produced losses in the fourth quarter and full year. Source

Earlier plans management reported on

  • Met: The company stated it met or exceeded its 2025 financial guidance across all key metrics. Source
  • Met: The company said it returned over $1 billion to shareholders in 2025. Source
  • Met: The company had been on track to submit the narcolepsy J-NDA by the end of 2025, and both applications are now under review. Source
  • Not stated: In the third-quarter release, the company anticipated approval by mid-2026; the fourth-quarter release gives a PDUFA date of July 30, 2026.
  • Not stated: In the third-quarter release, the company anticipated meaningful net cost savings over a multi-year period, with some reinvestment.
  • Not stated: In the third-quarter release the company planned an investor event in the first quarter of 2026; the fourth-quarter release sets it for March 19, 2026.

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.