Vertex Pharmaceuticals Inc. 13F holders
1,770 funds reported a position in Vertex Pharmaceuticals Inc. in their 13F for the quarter ended 30 June 2026, together 242.3 million shares worth $120.14 billion. Against the quarter before, 149 opened a position, 696 added, 616 trimmed and 110 sold out; together they bought a net 1.2 million shares. The largest holders: Capital World Investors, BlackRock, Inc. and Capital Research Global Investors.
What each fund did in VRTX against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in VRTX in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
4,696 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 993 reported a position in Vertex Pharmaceuticals Inc.: 60 opened one, 412 added, 309 trimmed and 44 sold out, a net 171,600 shares sold.
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 1 reported a position in Vertex Pharmaceuticals Inc. in a 13F for the quarter ended 30 September 2026, and 10 more in a 13F for an earlier quarter, the latest each has filed. The largest: Capital Research Global Investors, 19.5 million shares worth $9.68 billion, 1.4% of its reported book (its 13F for the quarter ended 30 June 2026). In the quarter, 1 fund added or opened a position and 0 trimmed or sold out; together they bought a net 64,121 shares, about $33.4 million at the funds' own value per share on 30 September 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Capital Research Global Investors | 19,490,637 | $9.68 billion | 1.4% | -1,635,327 | trimmed | 30 June 2026, an earlier quarter | 13F |
| Geode Capital Management | 6,081,969 | $3.17 billion | 0.2% | +64,121 | added | 30 September 2026 | 13F |
| Norges Bank | 2,971,681 | $1.48 billion | 0.1% | held | 30 June 2026, an earlier quarter | 13F | |
| FMR LLC | 1,457,158 | $723.8 million | 0.0% | -563,107 | trimmed | 30 June 2026, an earlier quarter | 13F |
| Citadel Advisors | 510,430 | $253.5 million | 0.1% | +171,132 | added | 30 June 2026, an earlier quarter | 13F |
| Millennium Management | 468,410 | $232.7 million | 0.2% | +437,587 | added | 30 June 2026, an earlier quarter | 13F |
| Renaissance Technologies | 320,008 | $159.0 million | 0.2% | -101,680 | trimmed | 30 June 2026, an earlier quarter | 13F |
| Two Sigma Investments | 285,000 | $141.6 million | 0.1% | -93,146 | trimmed | 30 June 2026, an earlier quarter | 13F |
| Baillie Gifford | 272,561 | $135.4 million | 0.1% | +73,140 | added | 30 June 2026, an earlier quarter | 13F |
| Bridgewater Associates | 10,865 | $5.4 million | 0.0% | -2,492 | trimmed | 30 June 2026, an earlier quarter | 13F |
| Point72 Asset Management | 2,625 | $1.3 million | 0.0% | +2,625 | new | 30 June 2026, an earlier quarter | 13F |
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| Capital World Investors | 26,115,014 | 10.78% | $12.97 billion | 1.53% | +746,890 | 13F |
| BlackRock, Inc. | 24,109,373 | 9.95% | $11.98 billion | 0.18% | +139,856 | 13F |
| Capital Research Global Investors | 19,490,637 | 8.04% | $9.68 billion | 1.35% | -1,635,327 | 13F |
| Vanguard Capital Management LLC | 16,580,713 | 6.84% | $8.24 billion | 0.18% | +67,903 | 13F |
| State Street Corp. | 11,871,459 | 4.90% | $5.90 billion | 0.17% | +141,320 | 13F |
| Invesco Ltd. | 8,043,052 | 3.32% | $4.00 billion | 0.32% | +150,441 | 13F |
| JPMorgan Chase & Co. | 6,517,600 | 2.69% | $3.26 billion | 0.19% | -515,556 | 13F |
| Geode Capital Management, LLC | 6,017,848 | 2.48% | $2.98 billion | 0.16% | -121,773 | 13F |
| Vanguard Portfolio Management LLC | 4,878,987 | 2.01% | $2.42 billion | 0.11% | -266,622 | 13F |
| Capital International Investors | 4,695,144 | 1.94% | $2.33 billion | 0.48% | -430,933 | 13F |
| Loomis Sayles & Co. L P | 3,920,953 | 1.62% | $1.95 billion | 2.44% | -82,868 | 13F |
| Franklin Resources Inc. | 3,347,253 | 1.38% | $1.66 billion | 0.36% | +2,796,121 | 13F |
| Wellington Management Group LLP | 3,247,658 | 1.34% | $1.61 billion | 0.28% | +35,069 | 13F |
| Morgan Stanley | 3,242,139 | 1.34% | $1.61 billion | 0.09% | +53,258 | 13F |
| UBS AM, a distinct business unit of UBS Asset Management Americas LLC | 3,086,683 | 1.27% | $1.53 billion | 0.28% | +29,287 | 13F |
| Bank of America Corp. | 3,039,178 | 1.25% | $1.51 billion | 0.10% | +160,995 | 13F |
| Jennison Associates LLC | 2,998,530 | 1.24% | $1.49 billion | 0.89% | +258,471 | 13F |
| Norges Bank | 2,971,681 | 1.23% | $1.48 billion | 0.15% | 13F | |
| AllianceBernstein L.P. | 3,019,315 | 1.25% | $1.35 billion | 0.45% | -891,471 | 13F |
| Ameriprise Financial Inc. | 2,604,822 | 1.08% | $1.29 billion | 0.26% | -28,659 | 13F |
| Northern Trust Corp. | 2,486,478 | 1.03% | $1.24 billion | 0.14% | -77,786 | 13F |
| Goldman Sachs Group Inc. | 2,481,761 | 1.02% | $1.23 billion | 0.13% | +63,886 | 13F |
| Clearbridge Investments, LLC | 2,342,915 | 0.97% | $1.16 billion | 0.96% | -358,060 | 13F |
| Victory Capital Management Inc. | 2,173,152 | 0.90% | $1.08 billion | 0.61% | +284,631 | 13F |
| Charles Schwab Investment Management Inc. | 2,041,282 | 0.84% | $1.01 billion | 0.14% | +120,411 | 13F |
| Legal & General Group Plc | 1,870,015 | 0.77% | $928.9 million | 0.19% | -85,749 | 13F |
| Price T Rowe Associates Inc. | 1,728,421 | 0.71% | $858.6 million | 0.09% | -31,701 | 13F |
| Bank of New York Mellon Corp | 1,672,623 | 0.69% | $830.8 million | 0.14% | +86,196 | 13F |
| Deutsche Bank AG | 1,579,110 | 0.65% | $784.4 million | 0.23% | +41,374 | 13F |
| Amundi | 1,546,509 | 0.64% | $768.2 million | 0.18% | +74,013 | 13F |
| Assenagon Asset Management S.A. | 1,519,128 | 0.63% | $754.6 million | 0.49% | 13F | |
| FMR LLC | 1,457,158 | 0.60% | $723.8 million | 0.03% | -563,107 | 13F |
| Vanguard Fiduciary Trust Co. | 1,425,390 | 0.59% | $708.0 million | 0.16% | -40,334 | 13F |
| Jupiter Topco LLC | 1,259,997 | 0.52% | $625.8 million | 0.26% | first 13F | 13F |
| Dimensional Fund Advisors LP | 1,168,956 | 0.48% | $580.7 million | 0.10% | +179,614 | 13F |
| WCM Investment Management, LLC | 1,152,094 | 0.48% | $575.6 million | 1.04% | +30,753 | 13F |
| Nuveen, LLC | 1,081,685 | 0.45% | $537.3 million | 0.13% | -2,810 | 13F |
| Royal Bank of Canada | 980,259 | 0.40% | $486.9 million | 0.08% | -131,612 | 13F |
| BNP Paribas Asset Management Holding S.A. | 897,893 | 0.37% | $446.0 million | 0.45% | +49,846 | 13F |
| Wells Fargo & Company | 749,528 | 0.31% | $372.3 million | 0.07% | +4,533 | 13F |
| Arrowstreet Capital, Limited Partnership | 738,378 | 0.30% | $366.8 million | 0.16% | +99,428 | 13F |
| Barclays PLC | 733,274 | 0.30% | $364.2 million | 0.12% | +70,011 | 13F |
| Swiss National Bank | 717,440 | 0.30% | $356.4 million | 0.19% | -27,160 | 13F |
| UBS Group AG | 712,259 | 0.29% | $353.8 million | 0.06% | +81,641 | 13F |
| Citigroup Inc. | 706,968 | 0.29% | $351.2 million | 0.16% | +24,161 | 13F |
| HSBC Holdings PLC | 676,247 | 0.28% | $335.8 million | 0.16% | +20,804 | 13F |
| Mitsubishi UFJ Asset Management Co., Ltd. | 647,193 | 0.27% | $321.5 million | 0.18% | +49,696 | 13F |
| AQR Capital Management LLC | 616,170 | 0.25% | $305.0 million | 0.11% | +445,139 | 13F |
| Sumitomo Mitsui Trust Group, Inc. | 611,907 | 0.25% | $304.0 million | 0.17% | -2,541 | 13F |
| American Century Companies Inc. | 580,901 | 0.24% | $288.6 million | 0.13% | -232,384 | 13F |
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on VRTX
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 244,600 | $121.5 million | 30 June 2026 | 13F |
| Citadel Advisors | Puts | 134,600 | $66.9 million | 30 June 2026 | 13F |
| Millennium Management | Puts | 49,000 | $24.3 million | 30 June 2026 | 13F |
| Millennium Management | Calls | 46,400 | $23.0 million | 30 June 2026 | 13F |
| Point72 Asset Management | Calls | 14,400 | $7.2 million | 30 June 2026 | 13F |
| Two Sigma Investments | Calls | 1,800 | $894,114 | 30 June 2026 | 13F |
| Point72 Asset Management | Puts | 1,600 | $794,768 | 30 June 2026 | 13F |
| Two Sigma Investments | Puts | 600 | $298,038 | 30 June 2026 | 13F |
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 14 May 2026 | 13G/A | Capital World Investors and 1 other | 25.7 million | 10.1% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 14 May 2026 | 13G/A | Capital Research Global Investors and 1 other | 21.1 million | 8.3% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 30 April 2026 | 13G | Vanguard Capital Management and 1 other | 19.0 million | 7.5% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 27 March 2026 | 13G/A | The Vanguard Group and 1 other | 0 | 0.0% | 13 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 12 February 2026 | 13G/A | Capital Research Global Investors and 1 other | 17.3 million | 6.8% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 31 August 2026 | 3 | $541.69 | SEC |
| 26 August 2026 | 1,828 | $552.85 | SEC |
| 25 August 2026 | 4,566 | $547.59 | SEC |
| 24 August 2026 | 237 | $548.05 | SEC |
| 5 August 2026 | 255 | $478.71 | SEC |
| 28 July 2026 | 608 | $479.00 | SEC |
| 22 July 2026 | 3,256 | $482.00 | SEC |
| 17 July 2026 | 102 | $486.03 | SEC |
| 16 July 2026 | 18 | $477.08 | SEC |