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Vertex Pharmaceuticals Inc. 13F holders

1,770 funds reported a position in Vertex Pharmaceuticals Inc. in their 13F for the quarter ended 30 June 2026, together 242.3 million shares worth $120.14 billion. Against the quarter before, 149 opened a position, 696 added, 616 trimmed and 110 sold out; together they bought a net 1.2 million shares. The largest holders: Capital World Investors, BlackRock, Inc. and Capital Research Global Investors.

Funds holding1,770+65 on Q1 2026
Shares they held242.3Mworth $120.14 billion
Net bought on the quarter1.2M sharesabout $606.1 million at the funds' values
Funds buying to selling845 to 726opened or added, to cut or sold
Opened 149Added 696Held 291Trimmed 616Sold out 110
Opened: 149 fundsAdded: 696 fundsHeld: 291 fundsTrimmed: 616 fundsSold out: 110 funds

What each fund did in VRTX against its 13F for the quarter before; a change under 0.1% of a holding counts as held

Q3 2024: 1,551 funds, 242.1 million shares1,551Q3 2024Q4 2024: 1,565 funds, 236.9 million shares1,565Q4 2024Q1 2025: 1,620 funds, 240.8 million shares1,620Q1 2025Q2 2025: 1,567 funds, 242.5 million shares1,567Q2 2025Q3 2025: 1,528 funds, 238.9 million shares1,528Q3 2025Q4 2025: 1,678 funds, 242.3 million shares1,678Q4 2025Q1 2026: 1,705 funds, 237.8 million shares1,705Q1 2026Q2 2026: 1,770 funds, 242.3 million shares1,770Q2 2026

Funds reporting a position in VRTX in their 13F, each quarter; hover a bar for the shares they held

Filed so far for the quarter to 30 September 2026

4,696 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 993 reported a position in Vertex Pharmaceuticals Inc.: 60 opened one, 412 added, 309 trimmed and 44 sold out, a net 171,600 shares sold.

FundChange in sharesShares nowStatusFiling
DekaBank Deutsche Girozentrale-310,265196,192trimmed13F
Assenagon Asset Management S.A.-299,8171,219,311trimmed13F
B. Metzler seel. Sohn & Co. AG-218,24213,139trimmed13F
Barclays PLC-208,595524,679trimmed13F
Agf Management Ltd-207,410561trimmed13F
Citigroup Inc.-174,367532,601trimmed13F
Montrusco Bolton Investments Inc.+149,888149,888new13F
Deutsche Bank AG+116,4311,695,541added13F
Pictet Asset Management Holding SA+101,910641,165added13F
AMF Tjanstepension AB+74,005388,770added13F
Ami Asset Management Corp.+66,94966,949new13F
Geode Capital Management, LLC+64,1216,081,969added13F
Principal Financial Group Inc.+54,016443,527added13F
E. Ohman J:or Asset Management AB+48,73157,554added13F
Mackenzie Financial Corp.+47,440150,368added13F
LPL Financial LLC+43,793332,904added13F
Mitsubishi UFJ Asset Management Co., Ltd.+35,218682,411added13F
Amundi-34,1531,512,356trimmed13F
Ofi Invest Asset Management+37,14747,596added13F
Swiss Life Asset Management Ltd+26,511118,125added13F
Robeco Institutional Asset Management B.V.+24,439428,835added13F
NorthCrest Asset Manangement, LLC+24,80526,359added13F
NEOS Investment Management LLC+23,704217,010added13F
Aberdeen Group plc+332,265542,866added13F
Livforsakringsbolaget Skandia, Omsesidigt+21,92027,700added13F

The largest moves in the name among the funds that have filed, against each fund's previous 13F.

The well-known funds

Of the 44 funds followed here, 1 reported a position in Vertex Pharmaceuticals Inc. in a 13F for the quarter ended 30 September 2026, and 10 more in a 13F for an earlier quarter, the latest each has filed. The largest: Capital Research Global Investors, 19.5 million shares worth $9.68 billion, 1.4% of its reported book (its 13F for the quarter ended 30 June 2026). In the quarter, 1 fund added or opened a position and 0 trimmed or sold out; together they bought a net 64,121 shares, about $33.4 million at the funds' own value per share on 30 September 2026. A change under 0.1% of a holding counts as held.

FundSharesValueOf its bookChange on the quarterStatusQuarter endedFiling
Capital Research Global Investors19,490,637$9.68 billion1.4%-1,635,327trimmed30 June 2026, an earlier quarter13F
Geode Capital Management6,081,969$3.17 billion0.2%+64,121added30 September 202613F
Norges Bank2,971,681$1.48 billion0.1%held30 June 2026, an earlier quarter13F
FMR LLC1,457,158$723.8 million0.0%-563,107trimmed30 June 2026, an earlier quarter13F
Citadel Advisors510,430$253.5 million0.1%+171,132added30 June 2026, an earlier quarter13F
Millennium Management468,410$232.7 million0.2%+437,587added30 June 2026, an earlier quarter13F
Renaissance Technologies320,008$159.0 million0.2%-101,680trimmed30 June 2026, an earlier quarter13F
Two Sigma Investments285,000$141.6 million0.1%-93,146trimmed30 June 2026, an earlier quarter13F
Baillie Gifford272,561$135.4 million0.1%+73,140added30 June 2026, an earlier quarter13F
Bridgewater Associates10,865$5.4 million0.0%-2,492trimmed30 June 2026, an earlier quarter13F
Point72 Asset Management2,625$1.3 million0.0%+2,625new30 June 2026, an earlier quarter13F
Value is what the fund reported.
Read moreChange is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.

The largest holders

FundSharesShare of allValueOf its bookChange in sharesFiling
Capital World Investors26,115,01410.78%$12.97 billion1.53%+746,89013F
BlackRock, Inc.24,109,3739.95%$11.98 billion0.18%+139,85613F
Capital Research Global Investors19,490,6378.04%$9.68 billion1.35%-1,635,32713F
Vanguard Capital Management LLC16,580,7136.84%$8.24 billion0.18%+67,90313F
State Street Corp.11,871,4594.90%$5.90 billion0.17%+141,32013F
Invesco Ltd.8,043,0523.32%$4.00 billion0.32%+150,44113F
JPMorgan Chase & Co.6,517,6002.69%$3.26 billion0.19%-515,55613F
Geode Capital Management, LLC6,017,8482.48%$2.98 billion0.16%-121,77313F
Vanguard Portfolio Management LLC4,878,9872.01%$2.42 billion0.11%-266,62213F
Capital International Investors4,695,1441.94%$2.33 billion0.48%-430,93313F
Loomis Sayles & Co. L P3,920,9531.62%$1.95 billion2.44%-82,86813F
Franklin Resources Inc.3,347,2531.38%$1.66 billion0.36%+2,796,12113F
Wellington Management Group LLP3,247,6581.34%$1.61 billion0.28%+35,06913F
Morgan Stanley3,242,1391.34%$1.61 billion0.09%+53,25813F
UBS AM, a distinct business unit of UBS Asset Management Americas LLC3,086,6831.27%$1.53 billion0.28%+29,28713F
Bank of America Corp.3,039,1781.25%$1.51 billion0.10%+160,99513F
Jennison Associates LLC2,998,5301.24%$1.49 billion0.89%+258,47113F
Norges Bank2,971,6811.23%$1.48 billion0.15%13F
AllianceBernstein L.P.3,019,3151.25%$1.35 billion0.45%-891,47113F
Ameriprise Financial Inc.2,604,8221.08%$1.29 billion0.26%-28,65913F
Northern Trust Corp.2,486,4781.03%$1.24 billion0.14%-77,78613F
Goldman Sachs Group Inc.2,481,7611.02%$1.23 billion0.13%+63,88613F
Clearbridge Investments, LLC2,342,9150.97%$1.16 billion0.96%-358,06013F
Victory Capital Management Inc.2,173,1520.90%$1.08 billion0.61%+284,63113F
Charles Schwab Investment Management Inc.2,041,2820.84%$1.01 billion0.14%+120,41113F
Legal & General Group Plc1,870,0150.77%$928.9 million0.19%-85,74913F
Price T Rowe Associates Inc.1,728,4210.71%$858.6 million0.09%-31,70113F
Bank of New York Mellon Corp1,672,6230.69%$830.8 million0.14%+86,19613F
Deutsche Bank AG1,579,1100.65%$784.4 million0.23%+41,37413F
Amundi1,546,5090.64%$768.2 million0.18%+74,01313F
Assenagon Asset Management S.A.1,519,1280.63%$754.6 million0.49%13F
FMR LLC1,457,1580.60%$723.8 million0.03%-563,10713F
Vanguard Fiduciary Trust Co.1,425,3900.59%$708.0 million0.16%-40,33413F
Jupiter Topco LLC1,259,9970.52%$625.8 million0.26%first 13F13F
Dimensional Fund Advisors LP1,168,9560.48%$580.7 million0.10%+179,61413F
WCM Investment Management, LLC1,152,0940.48%$575.6 million1.04%+30,75313F
Nuveen, LLC1,081,6850.45%$537.3 million0.13%-2,81013F
Royal Bank of Canada980,2590.40%$486.9 million0.08%-131,61213F
BNP Paribas Asset Management Holding S.A.897,8930.37%$446.0 million0.45%+49,84613F
Wells Fargo & Company749,5280.31%$372.3 million0.07%+4,53313F
Arrowstreet Capital, Limited Partnership738,3780.30%$366.8 million0.16%+99,42813F
Barclays PLC733,2740.30%$364.2 million0.12%+70,01113F
Swiss National Bank717,4400.30%$356.4 million0.19%-27,16013F
UBS Group AG712,2590.29%$353.8 million0.06%+81,64113F
Citigroup Inc.706,9680.29%$351.2 million0.16%+24,16113F
HSBC Holdings PLC676,2470.28%$335.8 million0.16%+20,80413F
Mitsubishi UFJ Asset Management Co., Ltd.647,1930.27%$321.5 million0.18%+49,69613F
AQR Capital Management LLC616,1700.25%$305.0 million0.11%+445,13913F
Sumitomo Mitsui Trust Group, Inc.611,9070.25%$304.0 million0.17%-2,54113F
American Century Companies Inc.580,9010.24%$288.6 million0.13%-232,38413F
The 50 largest of the 1,770 funds that reported a position in VRTX in their 13F for the quarter ended 30 June 2026, by the value each reported.
Read moreShare of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?

Options the funds reported on VRTX

FundOptionShares under the optionsValue of those sharesQuarter endedFiling
Citadel AdvisorsCalls244,600$121.5 million30 June 202613F
Citadel AdvisorsPuts134,600$66.9 million30 June 202613F
Millennium ManagementPuts49,000$24.3 million30 June 202613F
Millennium ManagementCalls46,400$23.0 million30 June 202613F
Point72 Asset ManagementCalls14,400$7.2 million30 June 202613F
Two Sigma InvestmentsCalls1,800$894,11430 June 202613F
Point72 Asset ManagementPuts1,600$794,76830 June 202613F
Two Sigma InvestmentsPuts600$298,03830 June 202613F
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
Read moreThey are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.

Schedule 13D and 13G filed on the name, last twelve months

FiledScheduleWhoHoldingOf the classEvent dateRule or purposeFiling
14 May 202613G/ACapital World Investors and 1 other25.7 million10.1%31 March 2026passive, institutional (13d-1(b))EDGAR
14 May 202613G/ACapital Research Global Investors and 1 other21.1 million8.3%31 March 2026passive, institutional (13d-1(b))EDGAR
30 April 202613GVanguard Capital Management and 1 other19.0 million7.5%31 March 2026passive, institutional (13d-1(b))EDGAR
27 March 202613G/AThe Vanguard Group and 1 other00.0%13 March 2026passive, institutional (13d-1(b))EDGAR
12 February 202613G/ACapital Research Global Investors and 1 other17.3 million6.8%31 December 2025passive, institutional (13d-1(b))EDGAR
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
Read moreAmendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13G

Fails to deliver

Settlement dateShares failedPriceFile
31 August 20263$541.69SEC
26 August 20261,828$552.85SEC
25 August 20264,566$547.59SEC
24 August 2026237$548.05SEC
5 August 2026255$478.71SEC
28 July 2026608$479.00SEC
22 July 20263,256$482.00SEC
17 July 2026102$486.03SEC
16 July 202618$477.08SEC
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.
Read moreLargest in the window: 4,566 on 25 August 2026. A fail is an operational fact about settlement, not a position.