Tango Therapeutics, Inc. 13F holders
247 funds reported a position in Tango Therapeutics, Inc. in their 13F for the quarter ended 30 June 2026, together 214.7 million shares worth $6.63 billion. Against the quarter before, 72 opened a position, 102 added, 53 trimmed and 22 sold out; together they bought a net 29.8 million shares. The largest holders: RTW Investments, LP, BlackRock, Inc. and FMR LLC.
What each fund did in TNGX against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in TNGX in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
2,671 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 23 reported a position in Tango Therapeutics, Inc.: 6 opened one, 7 added, 3 trimmed and 2 sold out, a net 110,890 shares bought.
| Fund | Change in shares | Shares now | Status | Filing |
|---|---|---|---|---|
| Congress Asset Management Co. | +97,708 | 478,454 | added | 13F |
| Assenagon Asset Management S.A. | -94,400 | 595,912 | trimmed | 13F |
| Y-Intercept (Hong Kong) Ltd | +61,636 | 61,636 | new | 13F |
| Guardian Partners Inc. | +30,000 | 30,000 | new | 13F |
| Connective Portfolio Management, LLC | +15,000 | 15,000 | new | 13F |
| SmartHarvest Portfolios, LLC | -7,256 | 39,113 | trimmed | 13F |
| Sterling Capital Management LLC | +4,152 | 4,647 | added | 13F |
| GF Fund Management Co. Ltd | +1,777 | 4,629 | added | 13F |
| Tema Etfs LLC | +1,560 | 56,944 | added | 13F |
| Farther Finance Advisors, LLC | -322 | 55 | trimmed | 13F |
| Gamma Investing LLC | +248 | 1,111 | added | 13F |
| Nisa Investment Advisors, LLC | +221 | 6,437 | added | 13F |
| Harbor Capital Advisors, Inc. | +210 | 210 | new | 13F |
| Signaturefd, LLC | +200 | 200 | new | 13F |
| TFC Financial Management, Inc. | +180 | 1,830 | added | 13F |
| SJS Investment Consulting Inc. | +2 | 2 | new | 13F |
| MassMutual Private Wealth & Trust, FSB | -8 | 0 | sold out | 13F |
| Physician Wealth Advisors, Inc. | -18 | 0 | sold out | 13F |
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 8 reported a position in Tango Therapeutics, Inc. in a 13F for the quarter ended 30 June 2026. The largest: FMR LLC, 12.3 million shares worth $385.5 million, 0.0% of its reported book. New this quarter: Renaissance Technologies. In the quarter, 7 funds added or opened a position and 1 trimmed or sold out; together they bought a net 4.8 million shares, about $150.7 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| FMR LLC | 12,333,339 | $385.5 million | 0.0% | +2,427,420 | added | 30 June 2026 | 13F |
| Geode Capital Management | 3,742,791 | $117.0 million | 0.0% | +1,067,014 | added | 30 June 2026 | 13F |
| Renaissance Technologies | 748,300 | $23.4 million | 0.0% | +748,300 | new | 30 June 2026 | 13F |
| Alyeska | 691,109 | $21.6 million | 0.1% | +673,911 | added | 30 June 2026 | 13F |
| Millennium Management | 496,036 | $15.5 million | 0.0% | +70,392 | added | 30 June 2026 | 13F |
| Point72 Asset Management | 298,339 | $9.3 million | 0.0% | -235,598 | trimmed | 30 June 2026 | 13F |
| Two Sigma Investments | 241,783 | $7.6 million | 0.0% | +68,651 | added | 30 June 2026 | 13F |
| Citadel Advisors | 181,059 | $5.7 million | 0.0% | +1,636 | added | 30 June 2026 | 13F |
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| RTW Investments, LP | 13,900,620 | 6.47% | $434.5 million | 3.71% | +600,000 | 13F |
| BlackRock, Inc. | 12,438,444 | 5.79% | $388.8 million | 0.01% | +3,690,399 | 13F |
| FMR LLC | 12,333,339 | 5.74% | $385.5 million | 0.02% | +2,427,420 | 13F |
| Farallon Capital Management, L.l.c. | 12,277,000 | 5.72% | $383.8 million | 2.27% | +3,179,589 | 13F |
| Boxer Capital Management, LLC | 10,876,219 | 5.07% | $340.0 million | 25.61% | no change | 13F |
| Goldman Sachs Group Inc. | 9,980,620 | 4.65% | $312.0 million | 0.03% | +4,904,228 | 13F |
| TCG Crossover Management, LLC | 9,081,201 | 4.23% | $283.9 million | 6.82% | -1,449,870 | 13F |
| Paradigm Biocapital Advisors LP | 6,357,523 | 2.96% | $198.7 million | 3.72% | +2,347,844 | 13F |
| Price T Rowe Associates Inc. | 6,348,827 | 2.96% | $198.5 million | 0.02% | +5,459,427 | 13F |
| Siren, L.L.C. | 6,179,364 | 2.88% | $193.2 million | 3.92% | +522,259 | 13F |
| State Street Corp. | 5,979,806 | 2.79% | $186.9 million | 0.01% | +1,327,912 | 13F |
| Vanguard Capital Management LLC | 5,957,348 | 2.77% | $186.2 million | 0.00% | +795,917 | 13F |
| Adage Capital Partners GP, L.l.c. | 5,600,000 | 2.61% | $175.1 million | 0.25% | -7,209,485 | 13F |
| Jupiter Topco LLC | 5,056,352 | 2.36% | $158.0 million | 0.06% | first 13F | 13F |
| Deep Track Capital, LP | 4,200,000 | 1.96% | $131.3 million | 1.93% | +1,450,000 | 13F |
| Deerfield Management Company, L.P. | 4,190,611 | 1.95% | $131.0 million | 1.63% | +43,798 | 13F |
| Woodline Partners LP | 4,000,567 | 1.86% | $125.1 million | 0.39% | -3,999,446 | 13F |
| TRV GP IV, LLC | 6,374,574 | 2.97% | $120.2 million | 47.37% | no change | 13F |
| Geode Capital Management, LLC | 3,742,791 | 1.74% | $117.0 million | 0.01% | +1,067,014 | 13F |
| Perceptive Advisors LLC | 3,377,000 | 1.57% | $105.6 million | 1.64% | +2,568,847 | 13F |
| Seven Fleet Capital Management LP | 3,228,144 | 1.50% | $95.7 million | 15.79% | +2,726,132 | 13F |
| Logos Global Management LP | 2,850,000 | 1.33% | $89.1 million | 3.83% | -150,000 | 13F |
| Caligan Partners LP | 2,500,103 | 1.16% | $78.2 million | 3.77% | +91,305 | 13F |
| Holocene Advisors, LP | 2,410,939 | 1.12% | $75.4 million | 0.17% | -1,521,664 | 13F |
| Commodore Capital LP | 2,250,000 | 1.05% | $70.3 million | 4.19% | new | 13F |
| Balyasny Asset Management L.P. | 2,016,379 | 0.94% | $63.0 million | 0.12% | -1,810,280 | 13F |
| Jefferies Financial Group Inc. | 2,010,534 | 0.94% | $62.8 million | 0.59% | new | 13F |
| Franklin Resources Inc. | 1,887,211 | 0.88% | $59.0 million | 0.01% | +590,928 | 13F |
| Candriam S.C.A. | 1,630,553 | 0.76% | $50.9 million | 0.23% | +361,307 | 13F |
| Vanguard Portfolio Management LLC | 1,585,111 | 0.74% | $49.6 million | 0.00% | +683,645 | 13F |
| JPMorgan Chase & Co. | 1,418,193 | 0.66% | $46.3 million | 0.00% | +1,350,867 | 13F |
| Polar Capital Holdings Plc | 1,480,740 | 0.69% | $46.3 million | 0.13% | new | 13F |
| Vivo Capital, LLC | 1,379,769 | 0.64% | $43.1 million | 3.94% | -775,011 | 13F |
| DV Equities, LLC | 1,318,551 | 0.61% | $41.2 million | 5.97% | first 13F | 13F |
| Cormorant Asset Management, LP | 1,300,000 | 0.61% | $40.6 million | 2.08% | -125,000 | 13F |
| Northern Trust Corp. | 1,231,933 | 0.57% | $38.5 million | 0.00% | +368,993 | 13F |
| Stempoint Capital LP | 1,223,019 | 0.57% | $38.2 million | 6.62% | +821,181 | 13F |
| Federated Hermes, Inc. | 1,214,613 | 0.57% | $38.0 million | 0.06% | +1,214,259 | 13F |
| Voya Investment Management LLC | 1,103,030 | 0.51% | $34.5 million | 0.03% | +927,561 | 13F |
| Charles Schwab Investment Management Inc. | 1,072,059 | 0.50% | $33.5 million | 0.00% | +233,384 | 13F |
| American Century Companies Inc. | 1,013,794 | 0.47% | $31.7 million | 0.01% | new | 13F |
| Nantahala Capital Management, LLC | 1,001,318 | 0.47% | $31.3 million | 0.95% | 13F | |
| Integral Health Asset Management, LLC | 1,000,000 | 0.47% | $31.3 million | 1.28% | +550,000 | 13F |
| Vanguard Fiduciary Trust Co. | 915,565 | 0.43% | $28.6 million | 0.01% | +252,644 | 13F |
| Nuveen, LLC | 890,170 | 0.41% | $27.8 million | 0.01% | +529,352 | 13F |
| Samlyn Capital, LLC | 766,473 | 0.36% | $24.0 million | 0.40% | new | 13F |
| Renaissance Technologies LLC | 748,300 | 0.35% | $23.4 million | 0.03% | new | 13F |
| Soleus Capital Management, L.P. | 709,000 | 0.33% | $22.2 million | 0.76% | +259,000 | 13F |
| ArrowMark Colorado Holdings LLC | 708,385 | 0.33% | $22.1 million | 0.92% | no change | 13F |
| Bellevue Group AG | 694,182 | 0.32% | $21.7 million | 0.46% | -1,705,818 | 13F |
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on TNGX
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 95,700 | $3.0 million | 30 June 2026 | 13F |
| Citadel Advisors | Puts | 62,500 | $2.0 million | 30 June 2026 | 13F |
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 14 August 2026 | 13G/A | Nextech Crossover I GP S.a. r.l. and 9 others | 0 | 0.0% | 30 June 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 August 2026 | 13G/A | TCG Crossover GP II, LLC and 5 others | 10.1 million | 7.0% | 30 June 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 August 2026 | 13G/A | Woodline Partners LP and 1 other | 4.0 million | 2.5% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 14 August 2026 | 13G/A | Farallon Capital Management, L.L.C. and 57 others | 16.3 million | 9.8% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 14 August 2026 | 13G | The Goldman Sachs Group, Inc. and 3 others | 9.7 million | 6.0% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 12 August 2026 | 13G/A | Adage Capital Management, L.P. and 5 others | 5.6 million | 3.4% | 30 June 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | Nextech Crossover I GP S.a. r.l. and 9 others | 7.3 million | 5.1% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 15 May 2026 | 13G | RTW Investments, LP and 3 others | 13.3 million | 9.3% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | TCG Crossover GP II, LLC and 5 others | 11.6 million | 8.1% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 15 May 2026 | 13G/A | Woodline Partners LP and 1 other | 8.0 million | 5.6% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 13 May 2026 | 13G/A | Adage Capital Management, L.P. and 5 others | 12.8 million | 9.0% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 11 May 2026 | 13G/A | Farallon Capital Partners, L.P. and 55 others | 11.3 million | 7.8% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 6 May 2026 | 13G | FMR LLC and 3 others | 9.9 million | 6.9% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 4 May 2026 | 13G/A | Invus Public Equities, L.P. and 15 others | 5.7 million | 4.0% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 27 March 2026 | 13G/A | The Vanguard Group and 1 other | 0 | 0.0% | 13 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | TCG Crossover GP II, L.P. and 5 others | 13.5 million | 10.0% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 17 February 2026 | 13G/A | EcoR1 Capital, LLC and 5 others | 0 | 0.0% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | Woodline Partners LP and 1 other | 10.1 million | 7.5% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 13 February 2026 | 13G/A | Invus Public Equities, L.P. and 15 others | 8.2 million | 6.1% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 12 February 2026 | 13G | Adage Capital Management, L.P. and 5 others | 10.6 million | 7.9% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 10 February 2026 | 13D/A | Third Rock Ventures IV, L.P. and 2 others | 6.4 million | 4.7% | 6 February 2026 | EDGAR | |
| 6 February 2026 | 13G/A | Farallon Capital Partners, L.P. and 61 others | 13.5 million | 10.0% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 30 January 2026 | 13G | The Vanguard Group and 1 other | 6.8 million | 5.0% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 21 January 2026 | 13G | BlackRock, Inc. and 1 other | 8.5 million | 6.3% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 21 November 2025 | 13D/A | Third Rock Ventures IV, L.P. and 2 others | 7.9 million | 5.8% | 19 November 2025 | EDGAR | |
| 14 November 2025 | 13G/A | TCG Crossover GP II, LLC and 5 others | 8.5 million | 6.3% | 30 September 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 November 2025 | 13D/A | Third Rock Ventures IV, L.P. and 2 others | 9.4 million | 7.0% | 12 November 2025 | EDGAR | |
| 13 November 2025 | 13G/A | Adage Capital Management, L.P. and 5 others | 2.5 million | 2.3% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 12 November 2025 | 13G/A | Farallon Capital Partners, L.P. and 55 others | 10.8 million | 9.7% | 30 September 2025 | passive, under 20% (13d-1(c)) | EDGAR |
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 30 September 2026 | 2,937 | $24.42 | SEC |
| 29 September 2026 | 2,251 | $24.30 | SEC |
| 28 September 2026 | 1 | $24.92 | SEC |
| 24 September 2026 | 491,105 | $24.45 | SEC |
| 8 September 2026 | 22,289 | $22.52 | SEC |
| 25 August 2026 | 1 | $24.51 | SEC |
| 24 August 2026 | 1,764 | $23.88 | SEC |
| 20 August 2026 | 67 | $25.20 | SEC |