Septerna (SEPN) Q3 FY2026 earnings: revenue $19 million, down 12.2% on the year
Septerna, Inc. (SEPN) reported revenue of $19 million for Q3 FY2026, the quarter ended 30 September 2026, down 12.2% on the same quarter a year earlier. Net income was -$27 million, and diluted earnings per share $-0.57. The figures are the company's own, from the 10-Q it filed with the SEC on 9 November 2026.
Revenue
$19 million
-12.2% on the year · -29.4% on the quarter
Q4 FY2024Q3 FY2026
Operating margin
-144.2%
12.2% a year earlier
Q4 FY2024Q3 FY2026
Net income
-$27 million
Q4 FY2024Q3 FY2026
Diluted EPS
-$0.57
Q4 FY2024Q3 FY2026
this quarterthe same quarter a year earlierHover a bar for its figure.
What management said
Guidance figures: 1 new, 1 kept.
Revenue below prior-year quarter: Third-quarter revenue was $18.9 million against $21.5 million a year earlier. Nine-month revenue was $72.2 million against $21.8 million. Second-quarter revenue was $26.7 million.
Net loss against prior-year profit: Net loss was $26.6 million, compared with $13.0 million in the second quarter and net income of $8.2 million a year earlier.
R&D spend up year on year: Research and development expenses were $36.6 million, up from $35.1 million in the second quarter and $24.3 million a year earlier. Nine-month R&D expenses were $101.2 million.
$ million except per share. Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.
Cash flow
$ million
Q3 FY2026
Q2 FY2026
Q3 FY2025
On the quarter
On the year
Last 8 quarters
Operating cash flow
-13.8
-22.2
169
Capital expenditure
0.1
0.0
0.0
+876.9%
Free cash flow
-13.9
-22.2
169
Free cash flow margin
-73.6%
-82.9%
785.3%
Cash from investing
33.5
18.4
-38.4
+81.8%
Cash from financing
62.7
16.8
0.3
+273.0%
+23,758.6%
Depreciation and amortisation
0.4
0.4
0.4
0.0%
0.0%
Share-based compensation
5.9
5.1
2.5
+16.7%
+133.9%
Diluted shares, weighted
47m
45m
46m
+4.2%
+2.9%
Shares outstanding at period end
47m
46m
45m
+3.8%
+6.2%
Cash flow lines for the quarter; where the company files them year to date, the quarter is the difference between two filings.
Balance sheet
$ million
Q3 FY2026
Q2 FY2026
Q3 FY2025
On the quarter
On the year
Last 8 quarters
Shareholders' equity
428
387
389
+10.7%
+10.1%
Debt
0.0
0.0
0.0
Operating lease liabilities
19.5
20.1
22.0
-3.3%
-11.4%
Other liabilities
172
160
196
+7.6%
-12.2%
Total liabilities and equity
619
567
607
+9.3%
+2.1%
Fixed assets
3.8
3.9
4.3
-1.8%
-11.3%
Investments
398
432
242
-7.8%
+64.8%
Cash and equivalents
167
84.7
320
+97.4%
-47.8%
Receivables
18.9
12.2
8.6
+55.3%
+118.4%
Other assets
31.5
34.2
32.1
-7.8%
-2.0%
Total assets
619
567
607
+9.3%
+2.1%
Questions
What was Septerna's revenue in Q3 FY2026?
Septerna (SEPN) reported revenue of $19 million for Q3 FY2026, the quarter ended 30 September 2026, down 12.2% on the same quarter a year earlier.
How much did Septerna earn in Q3 FY2026?
Net loss for Q3 FY2026 was $27 million, and the diluted loss per share $0.57.
When did Septerna report Q3 FY2026 results?
Septerna filed its 10-Q for the quarter ended 30 September 2026 with the SEC on 9 November 2026.
Each quarter as filed, linked to its filing. Read more* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS, and its diluted share count where shown, are from the company's results press release for that quarter, checked against the company's filed figures or a second data source. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.
10-Q for the period ended 30 September 2026, filed 9 November 2026: the filing.