Rhythm Pharmaceuticals, Inc. 13F holders
305 funds reported a position in Rhythm Pharmaceuticals, Inc. in their 13F for the quarter ended 30 June 2026, together 77.4 million shares worth $8.57 billion. Against the quarter before, 56 opened a position, 105 added, 100 trimmed and 41 sold out; together they bought a net 2.8 million shares. The largest holders: Ra Capital Management, L.P., BlackRock, Inc. and Baker Bros. Advisors LP.
Funds holding305+20 on Q1 2026
Shares they held77.4Mworth $8.57 billion
Net bought on the quarter2.8M sharesabout $306.5 million at the funds' values
Funds buying to selling161 to 141opened or added, to cut or sold
Opened 56Added 105Held 43Trimmed 100Sold out 41
What each fund did in RYTM against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in RYTM in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
2,671 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 41 reported a position in Rhythm Pharmaceuticals, Inc.: 6 opened one, 10 added, 7 trimmed and 5 sold out, a net 32,730 shares sold.
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 10 reported a position in Rhythm Pharmaceuticals, Inc. in a 13F for the quarter ended 30 June 2026. The largest: Geode Capital Management, 1.5 million shares worth $170.3 million, 0.0% of its reported book. New this quarter: Duquesne Family Office. Sold out: Alyeska. In the quarter, 4 funds added or opened a position and 6 trimmed or sold out; together they sold a net 870,624 shares, about $96.7 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Geode Capital Management | 1,533,698 | $170.3 million | 0.0% | +117,429 | added | 30 June 2026 | 13F |
| Capital Research Global Investors | 1,532,303 | $170.1 million | 0.0% | +416,843 | added | 30 June 2026 | 13F |
| Citadel Advisors | 1,263,652 | $140.3 million | 0.1% | -154,967 | trimmed | 30 June 2026 | 13F |
| FMR LLC | 1,025,840 | $113.9 million | 0.0% | -663,831 | trimmed | 30 June 2026 | 13F |
| Norges Bank | 685,844 | $76.1 million | 0.0% | held | 30 June 2026 | 13F | |
| Point72 Asset Management | 414,210 | $46.0 million | 0.1% | -432,591 | trimmed | 30 June 2026 | 13F |
| Millennium Management | 316,719 | $35.2 million | 0.0% | -135,106 | trimmed | 30 June 2026 | 13F |
| Duquesne Family Office | 203,618 | $22.6 million | 0.5% | +203,618 | new | 30 June 2026 | 13F |
| Renaissance Technologies | 68,281 | $7.6 million | 0.0% | -189,730 | trimmed | 30 June 2026 | 13F |
| Two Sigma Investments | 4,600 | $510,738 | 0.0% | +300 | added | 30 June 2026 | 13F |
| Alyeska | 0 | $0 | 0.0% | -32,589 | exited | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| Ra Capital Management, L.P. | 6,666,837 | 8.61% | $740.2 million | 6.43% | no change | 13F |
| BlackRock, Inc. | 6,156,902 | 7.95% | $683.6 million | 0.01% | -80,249 | 13F |
| Baker Bros. Advisors LP | 5,604,483 | 7.24% | $622.3 million | 3.13% | no change | 13F |
| Primecap Management Co. | 3,168,853 | 4.09% | $351.8 million | 0.21% | -248,656 | 13F |
| Vanguard Portfolio Management LLC | 3,136,895 | 4.05% | $348.3 million | 0.02% | +96,177 | 13F |
| Vanguard Capital Management LLC | 3,005,977 | 3.88% | $333.8 million | 0.01% | +38,152 | 13F |
| JPMorgan Chase & Co. | 2,652,746 | 3.43% | $292.2 million | 0.02% | +1,099,102 | 13F |
| Perceptive Advisors LLC | 2,586,295 | 3.34% | $287.2 million | 4.47% | +212,500 | 13F |
| State Street Corp. | 2,573,529 | 3.32% | $285.7 million | 0.01% | +301,678 | 13F |
| Price T Rowe Associates Inc. | 2,566,171 | 3.31% | $284.9 million | 0.03% | +911,295 | 13F |
| Westfield Capital Management Co. LP | 2,208,595 | 2.85% | $245.2 million | 0.80% | +279,472 | 13F |
| Goldman Sachs Group Inc. | 2,126,502 | 2.75% | $236.1 million | 0.03% | +161,070 | 13F |
| Federated Hermes, Inc. | 1,785,716 | 2.31% | $198.3 million | 0.28% | +499,413 | 13F |
| Polar Capital Holdings Plc | 1,663,632 | 2.15% | $184.7 million | 0.53% | +48,046 | 13F |
| Geode Capital Management, LLC | 1,533,698 | 1.98% | $170.3 million | 0.01% | +117,429 | 13F |
| Capital Research Global Investors | 1,532,303 | 1.98% | $170.1 million | 0.02% | +416,843 | 13F |
| Citadel Advisors LLC | 1,263,652 | 1.63% | $140.3 million | 0.08% | -154,967 | 13F |
| Checkpoint Capital L.P. | 1,186,000 | 1.53% | $131.7 million | 33.78% | -41,200 | 13F |
| Siren, L.L.C. | 1,136,275 | 1.47% | $126.2 million | 2.56% | +410,764 | 13F |
| Morgan Stanley | 1,112,240 | 1.44% | $123.5 million | 0.01% | +408,262 | 13F |
| FMR LLC | 1,025,840 | 1.33% | $113.9 million | 0.01% | -663,831 | 13F |
| Pictet Asset Management Holding SA | 957,785 | 1.24% | $106.3 million | 0.10% | +290,739 | 13F |
| Jupiter Topco LLC | 925,490 | 1.20% | $102.8 million | 0.04% | first 13F | 13F |
| Woodline Partners LP | 758,891 | 0.98% | $84.3 million | 0.26% | no change | 13F |
| AllianceBernstein L.P. | 894,723 | 1.16% | $77.8 million | 0.03% | -15,690 | 13F |
| Clearbridge Investments, LLC | 696,473 | 0.90% | $77.3 million | 0.06% | +87,036 | 13F |
| Rock Springs Capital Management LP | 692,598 | 0.89% | $76.9 million | 3.75% | +2,850 | 13F |
| Norges Bank | 685,844 | 0.89% | $76.1 million | 0.01% | 13F | |
| Franklin Resources Inc. | 577,033 | 0.75% | $64.1 million | 0.01% | -49,812 | 13F |
| Charles Schwab Investment Management Inc. | 552,738 | 0.71% | $61.4 million | 0.01% | +26,279 | 13F |
| Integral Health Asset Management, LLC | 550,000 | 0.71% | $61.1 million | 2.50% | -50,000 | 13F |
| Invesco Ltd. | 543,271 | 0.70% | $60.3 million | 0.01% | +178,965 | 13F |
| Northern Trust Corp. | 540,332 | 0.70% | $60.0 million | 0.01% | +41,818 | 13F |
| UBS AM, a distinct business unit of UBS Asset Management Americas LLC | 514,850 | 0.67% | $57.2 million | 0.01% | -26,600 | 13F |
| Wellington Management Group LLP | 488,747 | 0.63% | $54.3 million | 0.01% | +214,990 | 13F |
| Vanguard Fiduciary Trust Co. | 445,723 | 0.58% | $49.5 million | 0.01% | +23,812 | 13F |
| Loomis Sayles & Co. L P | 434,102 | 0.56% | $48.2 million | 0.06% | -31,000 | 13F |
| Candriam S.C.A. | 433,025 | 0.56% | $48.0 million | 0.22% | -31,315 | 13F |
| Squarepoint Ops LLC | 422,921 | 0.55% | $47.0 million | 0.09% | +159,953 | 13F |
| Point72 Asset Management, L.P. | 414,210 | 0.54% | $46.0 million | 0.07% | -432,591 | 13F |
| Sofinnova Investments, Inc. | 408,027 | 0.53% | $45.3 million | 2.42% | -42,069 | 13F |
| Ameriprise Financial Inc. | 401,634 | 0.52% | $44.6 million | 0.01% | +17,677 | 13F |
| Adage Capital Partners GP, L.l.c. | 397,000 | 0.51% | $44.1 million | 0.06% | -328,744 | 13F |
| Bank of New York Mellon Corp | 394,044 | 0.51% | $43.8 million | 0.01% | +100,746 | 13F |
| Braidwell LP | 381,128 | 0.49% | $42.3 million | 1.62% | +70,500 | 13F |
| Assenagon Asset Management S.A. | 372,982 | 0.48% | $41.4 million | 0.03% | 13F | |
| Artisan Partners Limited Partnership | 354,816 | 0.46% | $39.4 million | 0.06% | -35,853 | 13F |
| Bank of America Corp. | 325,470 | 0.42% | $36.1 million | 0.00% | -303,197 | 13F |
| Orbimed Advisors LLC | 322,900 | 0.42% | $35.9 million | 0.68% | +8,800 | 13F |
| Millennium Management LLC | 316,719 | 0.41% | $35.2 million | 0.03% | -135,106 | 13F |
The 50 largest of the 305 funds that reported a position in RYTM in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on RYTM
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Calls | 28,000 | $3.1 million | 30 June 2026 | 13F |
| Citadel Advisors | Puts | 17,500 | $1.9 million | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 13 October 2026 | 13G | Jpmorgan Chase & Co. and 1 other | 3.6 million | 5.1% | 30 September 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 15 May 2026 | 13G/A | Perceptive Advisors LLC and 7 others | 3.5 million | 5.1% | 31 March 2026 | passive, under 20% (13d-1(c)) | EDGAR |
| 30 April 2026 | 13G | Vanguard Capital Management and 1 other | 3.4 million | 5.0% | 31 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 27 March 2026 | 13G/A | The Vanguard Group and 1 other | 0 | 0.0% | 13 March 2026 | passive, institutional (13d-1(b)) | EDGAR |
| 17 February 2026 | 13G/A | RA Capital Management, L.P. and 7 others | 6.7 million | 9.9% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 12 February 2026 | 13G/A | Primecap Management Co and 1 other | 3.5 million | 5.2% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 30 January 2026 | 13G/A | The Vanguard Group and 1 other | 6.2 million | 9.3% | 31 December 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 14 November 2025 | 13G/A | Primecap Management Co and 1 other | 4.3 million | 6.4% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
| 30 October 2025 | 13G/A | The Vanguard Group and 1 other | 5.0 million | 7.5% | 30 September 2025 | passive, institutional (13d-1(b)) | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 30 September 2026 | 43 | $95.71 | SEC |
| 23 September 2026 | 2 | $99.27 | SEC |
| 26 August 2026 | 3,997 | $113.35 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.