PTC Therapeutics (PTCT) Q4 FY2025 earnings: revenue $165 million, down 22.7% on the year
PTC Therapeutics, Inc. (PTCT) reported revenue of $165 million for Q4 FY2025, the quarter ended 31 December 2025, down 22.7% on the same quarter a year earlier. Net income was -$135 million, and diluted earnings per share $-1.67. The figures are the company's own, from the 10-K it filed with the SEC on 19 February 2026.
The quarter, against the one before and a year earlier
| Line | Q4 FY2025 | Q3 FY2025 | Q4 FY2024 | Change on the year |
|---|---|---|---|---|
| Revenue | 165 | 211 | 213 | -22.7% |
| Research and development | 133 | 100 | 125 | +6.7% |
| Selling, general and administrative | 96.9 | 84.0 | 84.7 | +14.4% |
| Operating income | -71.3 | 3.0 | -162 | n/a |
| Operating margin | -43.3% | 1.4% | -76.2% | |
| Pre-tax income | -139 | -23.1 | -94.7 | n/a |
| Income tax | -4.1 | -39.0 | -28.8 | n/a |
| Net income | -135 | 15.9 | -65.9 | n/a |
| Net margin | -82.0% | 7.5% | -30.9% | |
| Diluted EPS | -$1.67 | $0.20 | -$0.85 | n/a |
Read more
Fourth quarters are the year less the first three quarters. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.Cash flow and capital returned
| Line | Q4 FY2025 | Q3 FY2025 | Q4 FY2024 | Change on the year |
|---|---|---|---|---|
| Operating cash flow | -34.3 | -66.3 | -30.0 | n/a |
| Capital expenditure | 2.4 | 3.4 | 3.8 | -37.0% |
| Free cash flow | -36.6 | -69.7 | -33.8 | n/a |
| Free cash flow margin | -22.3% | -33.1% | -15.8% | |
| Cash from investing | 34.0 | -290 | 268 | -87.3% |
| Cash from financing | 303 | 15.2 | 26.5 | +1042.8% |
| Depreciation and amortisation | 12.9 | 11.1 | 6.8 | +90.7% |
| Share-based compensation | 18.5 | 19.4 | 17.2 | +7.4% |
| Diluted shares, weighted | 81m | 87m | 77m | +5.0% |
| Shares outstanding at period end | 81m | 80m | 78m | +4.9% |
Cash flow lines for the quarter; where the company files them year to date, the quarter is the difference between two filings.
Balance sheet at quarter end
| Line | Q4 FY2025 | Q3 FY2025 | Q4 FY2024 | Change on the year |
|---|---|---|---|---|
| Shareholders' equity | -205 | -156 | -1,098 | n/a |
| Debt | 287 | 286 | 285 | +0.4% |
| Operating lease liabilities | 93.6 | 95.5 | 74.9 | +24.9% |
| Finance lease liabilities | 3.0 | 13.8 | 15.6 | -80.7% |
| Other liabilities | 2,721 | 2,404 | 2,427 | +12.1% |
| Total liabilities and equity | 2,899 | 2,644 | 1,705 | +70.0% |
| Fixed assets | 55.4 | 57.0 | 61.0 | -9.2% |
| Goodwill | 82.3 | 82.3 | 82.3 | +0.0% |
| Intangible assets | 389 | 396 | 119 | +227.2% |
| Investments | 961 | 1,015 | 360 | +166.9% |
| Cash and equivalents | 985 | 673 | 780 | +26.3% |
| Receivables | 182 | 203 | 159 | +14.5% |
| Inventory | 79.6 | 52.7 | 23.2 | +243.4% |
| Other assets | 166 | 164 | 121 | +36.4% |
| Total assets | 2,899 | 2,644 | 1,705 | +70.0% |
Questions
What was PTC Therapeutics' revenue in Q4 FY2025?
PTC Therapeutics (PTCT) reported revenue of $165 million for Q4 FY2025, the quarter ended 31 December 2025, down 22.7% on the same quarter a year earlier.
How much did PTC Therapeutics earn in Q4 FY2025?
Net loss for Q4 FY2025 was $135 million, and the diluted loss per share $1.67.
When did PTC Therapeutics report Q4 FY2025 results?
PTC Therapeutics filed its 10-K for the year that ended with the quarter on 19 February 2026; the fourth quarter is the year less the first three.
Quarterly results, the last 12 quarters
| Q3 FY2023 | Q4 FY2023 * | Q1 FY2024 | Q2 FY2024 | Q3 FY2024 | Q4 FY2024 * | Q1 FY2025 | Q2 FY2025 | Q3 FY2025 | Q4 FY2025 * | Q1 FY2026 | Q2 FY2026 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | 197 | 307 | 210 | 187 | 197 | 213 | 1,176 | 179 | 211 | 165 | 273 | 361 |
| R&D | 164 | 121 | 116 | 132 | 161 | 125 | 109 | 113 | 100 | 133 | 101 | 99.2 |
| SG&A | 80.9 | 76.3 | 73.3 | 69.5 | 73.5 | 84.7 | 81.0 | 85.3 | 84.0 | 96.9 | 86.2 | 80.6 |
| Operating income | -118 | 5.8 | -45.5 | -40.2 | -54.5 | -162 | 970 | -35.0 | 3.0 | -71.3 | 45.0 | 149 |
| Operating margin | -60% | 2% | -22% | -22% | -28% | -76% | 82% | -20% | 1% | -43% | 16% | 41% |
| Pre-tax income | -167 | -157 | -84.7 | -85.7 | -98.0 | -94.7 | 930 | -71.1 | -23.1 | -139 | -2.5 | 97.5 |
| Tax rate | n/a | n/a | n/a | n/a | n/a | n/a | 7% | n/a | n/a | n/a | n/a | 14% |
| Net income | -133 | -156 | -91.6 | -99.2 | -107 | -65.9 | 867 | -64.8 | 15.9 | -135 | -2.8 | 83.5 |
| Net margin | -68% | -51% | -44% | -53% | -54% | -31% | 74% | -36% | 8% | -82% | -1% | 23% |
| Diluted EPS | -$1.76 | -$2.06 | -$1.20 | -$1.29 | -$1.39 | -$0.85 | $10.04 | -$0.83 | $0.20 | -$1.67 | -$0.03 | $0.92 |
| Operating cash flow | -14.5 | -100 | 70.8 | -71.5 | -77.0 | -30.0 | 870 | -58.3 | -66.3 | -34.3 | -59.0 | 129 |
| Capital expenditure | 6.4 | 5.6 | 9.6 | n/a | 0.5 | 3.8 | 1.7 | 1.3 | 3.4 | 2.4 | 1.2 | 2.2 |
| Free cash flow | -20.9 | -106 | 61.2 | n/a | -77.5 | -33.8 | 868 | -59.6 | -69.7 | -36.6 | -60.2 | 127 |
| Shares outstanding | 75m | 76m | 77m | 77m | 77m | 78m | 79m | 79m | 80m | 81m | 83m | 83m |
| Filing | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-K | 10-Q | 10-Q | 10-Q | 10-K | 10-Q | 10-Q |
Read more
* The fourth quarter is the full year less the first three quarters, because the company files the year and not the quarter on its own. A fourth quarter's EPS and diluted share count are from the company's results press release for that quarter, used where the release gives the same revenue and net income as the table. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.Source
10-K for the period ended 31 December 2025, filed 19 February 2026, accession 0001104659-26-017575: the filing on EDGAR. All of PTC Therapeutics, Inc.'s filings: EDGAR company page.
The same record on your computer
GreekSoup is also a free program for your own computer. It reads these same filings for the names you follow, refreshed as they land, with no account. One pasted line installs it.