Orchestra BioMed Holdings, Inc. 13F holders
77 funds reported a position in Orchestra BioMed Holdings, Inc. in their 13F for the quarter ended 30 June 2026, together 27.7 million shares worth $119.4 million. Against the quarter before, 25 opened a position, 22 added, 15 trimmed and 13 sold out; together they bought a net 4.6 million shares. The largest holders: RTW Investments, LP, Perceptive Advisors LLC and BlackRock, Inc.
Funds holding77+12 on Q1 2026
Shares they held27.7Mworth $119.4 million
Net bought on the quarter4.6M sharesabout $19.8 million at the funds' values
Funds buying to selling47 to 28opened or added, to cut or sold
Opened 25Added 22Held 15Trimmed 15Sold out 13
What each fund did in OBIO against its 13F for the quarter before; a change under 0.1% of a holding counts as held
Funds reporting a position in OBIO in their 13F, each quarter; hover a bar for the shares they held
Filed so far for the quarter to 30 September 2026
3,405 funds have filed their 13F for the quarter so far; the rest are due by 16 November 2026. Of those, 15 reported a position in Orchestra BioMed Holdings, Inc.: 3 opened one, 7 added, 0 trimmed and 2 sold out, a net 13,769 shares sold.
| Fund | Change in shares | Shares now | Status | Filing |
|---|---|---|---|---|
| Daytona Street Capital LLC | +26,750 | 123,148 | added | 13F |
| China Universal Asset Management Co., Ltd. | +1,437 | 10,967 | added | 13F |
| Sterling Capital Management LLC | +1,167 | 1,307 | added | 13F |
| IFP Advisors, Inc | +920 | 90,528 | added | 13F |
| Mirae Asset Global Investments Co., Ltd. | +393 | 3,071 | added | 13F |
| Gamma Investing LLC | +296 | 296 | new | 13F |
| SJS Investment Consulting Inc. | +193 | 193 | new | 13F |
| Farther Finance Advisors, LLC | +142 | 142 | new | 13F |
| GF Fund Management Co. Ltd | +104 | 1,277 | added | 13F |
| Caitong International Asset Management Co., Ltd | +11 | 26 | added | 13F |
| AdvisorNet Financial, Inc | -1,696 | 0 | sold out | 13F |
| Y-Intercept (Hong Kong) Ltd | -43,486 | 0 | sold out | 13F |
The largest moves in the name among the funds that have filed, against each fund's previous 13F.
The well-known funds
Of the 44 funds followed here, 6 reported a position in Orchestra BioMed Holdings, Inc. in a 13F for the quarter ended 30 June 2026. The largest: Geode Capital Management, 1.0 million shares worth $4.4 million, 0.0% of its reported book. Sold out: Millennium Management, Point72 Asset Management. In the quarter, 2 funds added or opened a position and 5 trimmed or sold out; together they sold a net 327,264 shares, about $1.4 million at the funds' own value per share on 30 June 2026. A change under 0.1% of a holding counts as held.
| Fund | Shares | Value | Of its book | Change on the quarter | Status | Quarter ended | Filing |
|---|---|---|---|---|---|---|---|
| Geode Capital Management | 1,007,908 | $4.4 million | 0.0% | +522,416 | added | 30 June 2026 | 13F |
| Alyeska | 1,000,000 | $4.3 million | 0.0% | no change | held | 30 June 2026 | 13F |
| Renaissance Technologies | 90,000 | $388,350 | 0.0% | +19,100 | added | 30 June 2026 | 13F |
| Citadel Advisors | 56,191 | $242,464 | 0.0% | -22,994 | trimmed | 30 June 2026 | 13F |
| Two Sigma Investments | 22,563 | $97,359 | 0.0% | -37,544 | trimmed | 30 June 2026 | 13F |
| FMR LLC | 265 | $1,142 | 0.0% | -17,811 | trimmed | 30 June 2026 | 13F |
| Millennium Management | 0 | $0 | 0.0% | -702,543 | exited | 30 June 2026 | 13F |
| Point72 Asset Management | 0 | $0 | 0.0% | -87,888 | exited | 30 June 2026 | 13F |
Value is what the fund reported.
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Change is shares against the fund's previous 13F; a fund with one filing read shows no change. 13Fs cover long US positions of managers above $100 million and are filed up to 45 days after the quarter.The largest holders
| Fund | Shares | Share of all | Value | Of its book | Change in shares | Filing |
|---|---|---|---|---|---|---|
| RTW Investments, LP | 9,556,063 | 34.51% | $41.2 million | 0.35% | +1,250,000 | 13F |
| Perceptive Advisors LLC | 5,037,906 | 18.19% | $21.7 million | 0.34% | no change | 13F |
| BlackRock, Inc. | 2,510,387 | 9.07% | $10.8 million | 0.00% | +1,874,673 | 13F |
| Vanguard Capital Management LLC | 2,022,916 | 7.30% | $8.7 million | 0.00% | -181,403 | 13F |
| Geode Capital Management, LLC | 1,007,908 | 3.64% | $4.4 million | 0.00% | +522,416 | 13F |
| Alyeska Investment Group, L.P. | 1,000,000 | 3.61% | $4.3 million | 0.01% | no change | 13F |
| Propel Bio Management, LLC | 896,701 | 3.24% | $3.9 million | 2.02% | no change | 13F |
| UBS AM, a distinct business unit of UBS Asset Management Americas LLC | 642,154 | 2.32% | $2.8 million | 0.00% | new | 13F |
| State Street Corp. | 516,050 | 1.86% | $2.2 million | 0.00% | +346,640 | 13F |
| Rice Hall James & Associates, LLC | 424,000 | 1.53% | $1.8 million | 0.09% | +404,999 | 13F |
| Charles Schwab Investment Management Inc. | 349,544 | 1.26% | $1.5 million | 0.00% | +84,045 | 13F |
| Northern Trust Corp. | 343,640 | 1.24% | $1.5 million | 0.00% | +225,366 | 13F |
| UBS Group AG | 325,773 | 1.18% | $1.4 million | 0.00% | +275,463 | 13F |
| Vanguard Fiduciary Trust Co. | 292,253 | 1.06% | $1.3 million | 0.00% | +57,039 | 13F |
| Vanguard Portfolio Management LLC | 274,973 | 0.99% | $1.2 million | 0.00% | new | 13F |
| Knott David M Jr | 253,651 | 0.92% | $1.1 million | 0.58% | no change | 13F |
| Flat Footed LLC | 251,372 | 0.91% | $1.1 million | 0.19% | new | 13F |
| Simplify Asset Management Inc. | 219,387 | 0.79% | $946,655 | 0.01% | no change | 13F |
| Goldman Sachs Group Inc. | 179,606 | 0.65% | $775,000 | 0.00% | +24,364 | 13F |
| Dafna Capital Management LLC | 126,841 | 0.46% | $547,319 | 0.10% | no change | 13F |
| Renaissance Technologies LLC | 90,000 | 0.32% | $388,350 | 0.00% | +19,100 | 13F |
| IFP Advisors, Inc | 89,608 | 0.32% | $386,659 | 0.01% | -9,279 | 13F |
| Daytona Street Capital LLC | 96,398 | 0.35% | $379,336 | 0.28% | +43,798 | 13F |
| Bank of New York Mellon Corp | 86,103 | 0.31% | $371,534 | 0.00% | new | 13F |
| Bridgeway Capital Management, LLC | 80,600 | 0.29% | $347,789 | 0.01% | +10,000 | 13F |
| Susquehanna International Group, LLP | 65,804 | 0.24% | $283,944 | 0.00% | -31,717 | 13F |
| Citadel Advisors LLC | 56,191 | 0.20% | $242,464 | 0.00% | -22,994 | 13F |
| Nuveen, LLC | 52,118 | 0.19% | $224,889 | 0.00% | new | 13F |
| Holos Integrated Wealth LLC | 51,595 | 0.19% | $204,316 | 0.10% | no change | 13F |
| NewEdge Advisors, LLC | 44,083 | 0.16% | $190,218 | 0.00% | no change | 13F |
| Y-Intercept (Hong Kong) Ltd | 43,486 | 0.16% | $187,642 | 0.00% | new | 13F |
| Deutsche Bank AG | 39,672 | 0.14% | $171,383 | 0.00% | new | 13F |
| XTX Topco Ltd | 38,814 | 0.14% | $167,482 | 0.00% | new | 13F |
| Wells Fargo & Company | 36,356 | 0.13% | $156,876 | 0.00% | new | 13F |
| HighTower Advisors, LLC | 35,375 | 0.13% | $152,643 | 0.00% | +17,100 | 13F |
| Affinity Asset Advisors, LLC | 33,400 | 0.12% | $144,121 | 0.01% | -369,150 | 13F |
| Price T Rowe Associates Inc. | 32,689 | 0.12% | $142,000 | 0.00% | new | 13F |
| Rhumbline Advisers | 31,940 | 0.12% | $137,813 | 0.00% | new | 13F |
| Morgan Stanley | 29,160 | 0.11% | $125,826 | 0.00% | -6,479 | 13F |
| Algert Global LLC | 28,486 | 0.10% | $122,917 | 0.00% | +13,830 | 13F |
| Meramec Financial Planners, LLC | 30,000 | 0.11% | $114,600 | 0.04% | no change | 13F |
| Axq Capital, LP | 25,448 | 0.09% | $109,808 | 0.01% | new | 13F |
| Invesco Ltd. | 24,689 | 0.09% | $106,533 | 0.00% | new | 13F |
| MetLife Investment Management, LLC | 23,994 | 0.09% | $103,534 | 0.00% | new | 13F |
| Bank of America Corp. | 23,822 | 0.09% | $102,792 | 0.00% | -28,939 | 13F |
| JPMorgan Chase & Co. | 20,880 | 0.08% | $99,181 | 0.00% | +16,622 | 13F |
| Two Sigma Investments, LP | 22,563 | 0.08% | $97,359 | 0.00% | -37,544 | 13F |
| Canada Pension Plan Investment Board | 21,100 | 0.08% | $91,047 | 0.00% | +9,800 | 13F |
| New York State Common Retirement Fund | 20,400 | 0.07% | $88,026 | 0.00% | new | 13F |
| Citigroup Inc. | 20,165 | 0.07% | $87,012 | 0.00% | -5,364 | 13F |
The 50 largest of the 77 funds that reported a position in OBIO in their 13F for the quarter ended 30 June 2026, by the value each reported.
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Share of all is the fund's part of all the shares the funds reported. Change is shares against the fund's 13F for the quarter before. A 13F lists a manager's long positions in US-listed shares at the quarter's end. What is a 13F?Options the funds reported on OBIO
| Fund | Option | Shares under the options | Value of those shares | Quarter ended | Filing |
|---|---|---|---|---|---|
| Citadel Advisors | Puts | 17,600 | $75,944 | 30 June 2026 | 13F |
| Citadel Advisors | Calls | 12,100 | $52,212 | 30 June 2026 | 13F |
A 13F lists calls and puts by the shares they cover and what those shares were worth at the quarter's end, not what the options cost.
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They are not counted in the holdings above. A put gains when the stock falls, a call when it rises, and a fund may hold either to hedge.Schedule 13D and 13G filed on the name, last twelve months
| Filed | Schedule | Who | Holding | Of the class | Event date | Rule or purpose | Filing |
|---|---|---|---|---|---|---|---|
| 29 April 2026 | 13D/A | RTW Investments, LP and 3 others | 11.9 million | 19.2% | 27 April 2026 | EDGAR | |
| 27 February 2026 | 13G/A | Medtronic plc and 3 others | 10.1 million | 17.8% | 31 December 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 25 February 2026 | 13D/A | RTW Investments, LP and 3 others | 11.9 million | 19.7% | 23 February 2026 | Item 4 of the Schedule 13D is hereby amended and supplemented as follows: On February 23, 2026, the RTW Funds submitted notices to the Issuer increasing the Maximum Percentage under the Pre-Funded Warrants from 9.99% to 19.99%. In accordanc | EDGAR |
| 19 November 2025 | 13G | Tasso Partners, LLC and 3 others | 3.1 million | 5.5% | 15 November 2025 | passive, under 20% (13d-1(c)) | EDGAR |
| 14 November 2025 | 13G/A | Perceptive Advisors LLC and 5 others | 5.7 million | 10.0% | 30 September 2025 | passive, under 20% (13d-1(c)) | EDGAR |
A Schedule 13D is filed by anyone who crosses 5% of a class with intent to influence; a 13G by a passive holder.
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Amendments (/A) report a change, including an exit to zero. Holding and percentage are as the filer stated them on the cover page; the purpose is the filer's own words, cut short. 13D and 13GFails to deliver
| Settlement date | Shares failed | Price | File |
|---|---|---|---|
| 11 August 2026 | 1,040 | $4.46 | SEC |
| 21 July 2026 | 57 | $3.71 | SEC |
| 16 July 2026 | 222 | $3.65 | SEC |
Shares that failed to deliver at settlement, per day, from the SEC's half-month files, which arrive about two weeks after the period.