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Myriad Genetics Inc.: Q1 FY2026 earnings call

What management said about Q1 FY2026, from the documents filed with the SEC on 5 May 2026: press release. Guidance figures: 4 kept. The quarter’s numbers.

Key takeaways

  • Revenue grew 2% year-over-year: Revenue was $200.4 million against $195.9 million a year earlier. Average revenue per test rose 2%, and test volume was stable at 385,000. Source
  • Net loss and adjusted EBITDA: The GAAP net loss was $34.1 million, or $0.36 per share. Adjusted loss per share was $0.09, and adjusted EBITDA was $(4.5) million. Source
  • Prenatal revenue and volume fell: Prenatal Health revenue was $41.9 million, down 15%, with volume down 12% to 153,000 tests. Management cited a difficult year-over-year comparison. Source
  • Precise MRD launched for breast cancer: The ultrasensitive Precise MRD assay launched, with a limited launch for breast cancer patients. Management said early feedback has been positive. Source
  • Women's Health impairment of $5.4 million: A $5.4 million goodwill and long-lived asset impairment was recorded on the Women's Health reporting unit and certain intangible assets. Source
  • Gross margin 68.7%, up 20 basis points: Gross margin was 68.7% in the first quarter of 2026, up 20.0 basis points from the first quarter of 2025. Source

“We are seeing strong performance across a number of key areas, including the Cancer Care Continuum as we begin to realize a return on our focused strategy.”

Sam Raha, President and CEO

Guidance

AreaPeriodFigureAgainst last quarter
Revenue SourceFull year 2026$860 - $880 millionKept
Revenue phasing SourceSecond half vs first half 20262H’26 revenue greater than 1H’26Kept
Adjusted gross margin SourceFull year 202668% - 69%Kept
Adjusted EBITDA SourceFull year 2026$37 - $49 millionKept

What changed from last quarter

  • Guidance kept: The release is titled as reiterating full-year 2026 financial guidance. Source
  • Guidance withdrawn: The prior release’s first-quarter adjusted EBITDA expectation is not repeated in this release.
  • New: Precise MRD, an ultrasensitive assay, was launched in the quarter. Source
  • New: FDA approved MyChoice CDx as companion diagnostic for Zejula in advanced ovarian cancer. Source
  • New: Japan’s health ministry approved MyChoice CDx for prostate cancer patients, as a companion diagnostic for Lynparza. Source
  • New: A national payor updated its medical policy to cover expanded carrier screen tests. Source
  • New: A dedicated hereditary cancer sales force was implemented, with other programs for germline testing. Source

Results and growth drivers

  • Revenue grew 2% year-over-year: Revenue was $200.4 million against $195.9 million a year earlier. Average revenue per test rose 2%, and test volume was stable at 385,000. Source
  • Net loss and adjusted EBITDA: The GAAP net loss was $34.1 million, or $0.36 per share. Adjusted loss per share was $0.09, and adjusted EBITDA was $(4.5) million. Source
  • Test volume flat, mix shifted: Cancer Care Continuum and Mental Health volume growth offset a Prenatal Health volume decline, leaving total volume unchanged year-over-year. Source

Product categories and volumes

  • Cancer Care Continuum revenue up 4%: Cancer Care Continuum revenue was $120.2 million, up 4%, with volume up 13% to 96,000 tests. Hereditary cancer revenue rose 5% on 14% higher volume. Source
  • Prenatal revenue and volume fell: Prenatal Health revenue was $41.9 million, down 15%, with volume down 12% to 153,000 tests. Management cited a difficult year-over-year comparison. Source
  • Mental Health revenue rose 24%: Mental Health revenue was $38.3 million, up 24%, on 7% GeneSight volume growth to 136,000 tests and improved reimbursement trends. Source
  • Prolaris revenue grew 3%: Prolaris testing revenue grew 3% year-over-year in the quarter, as the company continues work on its first AI-enabled prostate cancer test. Source

“Our limited launch of Precise MRD for breast cancer patients has received positive early feedback and we remain on track with our other planned launches in 2026, as part of our milestone-rich year.”

Sam Raha, President and CEO

Products, approvals and data

  • Precise MRD launched for breast cancer: The ultrasensitive Precise MRD assay launched, with a limited launch for breast cancer patients. Management said early feedback has been positive. Source
  • FDA approval for MyChoice CDx: The FDA approved MyChoice CDx as the companion diagnostic for Zejula in patients with advanced ovarian cancer. Source
  • Japan approval for prostate use: Japan approved MyChoice CDx for prostate cancer patients. Clinicians in Japan can now order the test for HRD in ovarian cancer and BRCA status in breast and prostate cancer. Source
  • Payor coverage for carrier screens: A national payor updated its medical policy in April 2026 to cover expanded carrier screen tests, including the Foresight Universal Plus test. Source
  • Data presented at spring meetings: Data were shared at annual clinical society meetings, including on Precise MRD after adjuvant therapy in ovarian cancer. Source

Costs, impairment and interest

  • Adjusted operating expenses up $7.9 million: GAAP operating expenses were $168.3 million, up $5.1 million. Adjusted operating expenses were $148.5 million, reflecting multi-year strategic investment. Source
  • Women's Health impairment of $5.4 million: A $5.4 million goodwill and long-lived asset impairment was recorded on the Women's Health reporting unit and certain intangible assets. Source
  • Interest expense rose to $4.1 million: Interest expense was $4.1 million against $0.8 million a year earlier, and total other expense was $3.4 million. Source
  • Severance now reported under realignment: Severance costs previously in other one-time expenses are now reported under strategic realignment, and $1.7 million for the prior-year quarter was reclassified. Source

“We are confident these tests will be important drivers of our growth in 2027 and beyond.”

Sam Raha, President and CEO

Gross margin and pricing

  • Gross margin 68.7%, up 20 basis points: Gross margin was 68.7% in the first quarter of 2026, up 20.0 basis points from the first quarter of 2025. Source
  • Adjusted gross margin 68.8% against 69.0%: Adjusted gross profit was $137.9 million against $135.1 million, giving an adjusted gross margin of 68.8% against 69.0% a year earlier. Source
  • Cost of revenue rose slightly: Cost of revenue was $62.8 million against $61.7 million, and gross profit was $137.6 million against $134.2 million. Source

Cash, liquidity and shareholder returns

  • Cash used in operations $15.7 million: Adjusted operating cash outflow was $13.4 million in the quarter, after the reported net cash used in operating activities of $15.7 million. Source
  • Adjusted free cash flow negative: Capital expenditures and capitalized software totaled $6.5 million, resulting in adjusted free cash flow of $(19.9) million. Source
  • Cash balance down to $124.4 million: Cash and cash equivalents were $124.4 million at March 31, 2026, down from $149.6 million at December 31, 2025. Source
  • No buybacks or dividends described: Financing activities used $3.0 million in the quarter. The release does not describe share repurchases or dividends. Source

Strategy and launch plans

  • Dedicated hereditary sales force: The company implemented a dedicated hereditary cancer sales force and other programs, aimed at expected continued growth in germline testing. Source
  • Milestone-rich year of launches: Management described 2026 as a milestone-rich year and expects these tests to be drivers of growth in 2027 and beyond. Source
  • CONNECTOR study enrollment progressing: Enrollment in the multi-site CONNECTOR study of the FirstGene prenatal screen continues to progress, according to the release. Source
  • Reiterated guidance and launch plans: The release states management remains confident in the 2026 launch plan, with the guidance ranges reiterated under the guidance section. Source

Coming up, as management said on 5 May 2026

  • AI prostate test launch in Q2: Launch of the AI-enabled prostate cancer test, developed with PATHOMIQ, is expected in the second quarter of 2026. Source
  • Prenatal performance expected to improve: Management expects improved performance in Prenatal Health for the remainder of 2026, following steps it describes as decisive. Source
  • CONNECTOR study could support launches: If successful, the CONNECTOR study is expected to support future commercial launch activities and expand prenatal testing capabilities. Source

Figures management reported

FigureReported
Cancer Care Continuum product revenue Source$120.2 million, up 4%
Prenatal Health product revenue Source$41.9 million, down 15%
GeneSight product revenue Source$38.3 million, up 24%
Prolaris testing revenue growth Sourceup 3% year-over-year
Pipeline launch SourcePrecise MRD launched; limited launch for breast cancer
FDA approval SourceMyChoice CDx companion diagnostic for Zejula
Japan approval SourceMyChoice CDx companion diagnostic for Lynparza, prostate cancer
R&D expense Source$27.1 million (prior year $27.5 million)

Risks management discussed

  • Operational: Prenatal volume was affected by disruption from the 2Q25 order management system implementation, which management said it continues to address. Source

Earlier plans management reported on

  • Met: The prior release expected a targeted alpha launch in March 2026. This release reports Precise MRD as launched, with a limited launch for breast cancer.
  • On track: Management said it remains on track with its other planned launches in 2026. Source
  • Not stated: The prior release planned a FirstGene commercial launch in the second half of 2026. This release ties future commercial launch activity to the CONNECTOR study.
  • Not stated: The prior release gave a first-quarter revenue range of $200 to $203 million. This release reports first-quarter revenue of $200.4 million.

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.