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Eli Lilly & Co.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 5 August 2026: press release. Guidance figures: 2 raised, 3 lowered, 1 kept. The quarter’s numbers.

Key takeaways

  • Revenue rose 48% to $23.0 billion: Q2 revenue was $22,974 million, up from $15,558 million. Volume rose 60%, partly offset by a 13% fall in realized prices. Six-month revenue was $42,773 million, up 51%. Source
  • Reported EPS rose 26% to $7.94: Non-GAAP EPS was $8.38, up 33% from $6.31. Reported and non-GAAP EPS both include $3.03 of acquired IPR&D charges, against $0.14 a year earlier. Six-month reported diluted EPS was $16.19. Source
  • Full-year revenue range raised: The 2026 revenue range rose to $85.0 billion to $87.0 billion from $82 billion to $85 billion. The non-GAAP EPS range is now $35.50 to $36.50, with the top end lowered. Source
  • Ex-U.S. revenue up 80%: Revenue outside the U.S. rose to $8.6 billion, with volume up 113%, mostly on Mounjaro. Realized prices fell 36%, mainly because Mounjaro was added to China's NRDL. Jardiance included a $250 million milestone. Source
  • Mounjaro revenue up 91%: Worldwide Mounjaro revenue was $9.9 billion. U.S. Mounjaro revenue was $4.8 billion, up 45%. Revenue outside the U.S. was $5.2 billion, up 172%, mostly on volume growth. Source
  • Retatrutide data package now complete: Three additional Phase 3 obesity trials of retatrutide were positive. The company says the clinical data package is complete for global registrations in obesity, sleep apnea and knee pain. Source
  • $2.8 billion IPR&D charges in Q2: Acquired IPR&D charges were $2.8 billion, against $154 million a year earlier. Six-month charges were $3,360 million. Reported and non-GAAP EPS both include these charges. Source

“Lilly's momentum continues, as we delivered 48% revenue growth and raised our full-year guidance,”

David A. Ricks, Lilly chair and CEO

Guidance

AreaPeriodFigureAgainst last quarter
Revenue SourceFY2026$85.0 billion to $87.0 billionRaised from $82 billion to $85 billion
Performance margin (non-GAAP) SourceFY202649.0% to 50.5%Raised from 47.0% to 48.5%
Tax rate (non-GAAP) SourceFY202618% to 19%Kept
Earnings per share (non-GAAP) SourceFY2026$35.50 to $36.50Lowered from $35.50 to $37.00
Shares outstanding (assumption) SourceFY2026approximately 894 millionLowered from approximately 895 million
Euro exchange rate (assumption) SourceFY20261.14 (Euro)Lowered from 1.16 (Euro)
Excluded acquired IPR&D cut-off Sourceafter June 30, 2026IPR&D incurred after June 30, 2026 not included

What changed from last quarter

  • Guidance raised: Full-year revenue guidance raised. Both ends of the range moved up. Source
  • Guidance raised: Non-GAAP performance margin range raised by 2 percentage points at each end. Source
  • Guidance lowered: Non-GAAP EPS range top end lowered by $0.50, to $36.50, after Q2 acquired IPR&D charges. Source
  • Guidance kept: Non-GAAP tax rate range kept at 18% to 19%. Source
  • New: Foundayo added to the list of Key Products in Q2 2026. Source
  • New: Four acquisitions agreed in Q1 2026 were reported as completed in Q2 2026. Source
  • New: Agreement to acquire AtaiBeckley, Inc. entered after quarter end. Source
  • New: Retatrutide clinical data package described as complete for global registrations. Source
  • New: Additional $4.5 billion committed to Indiana manufacturing sites. Source
  • New: Submission for orforglipron in type 2 diabetes made in the U.S. in the quarter. Source

Revenue and earnings growth

  • Revenue rose 48% to $23.0 billion: Q2 revenue was $22,974 million, up from $15,558 million. Volume rose 60%, partly offset by a 13% fall in realized prices. Six-month revenue was $42,773 million, up 51%. Source
  • Reported EPS rose 26% to $7.94: Non-GAAP EPS was $8.38, up 33% from $6.31. Reported and non-GAAP EPS both include $3.03 of acquired IPR&D charges, against $0.14 a year earlier. Six-month reported diluted EPS was $16.19. Source
  • Operating income up 31%: Q2 operating income was $8,978 million, up from $6,867 million. Reported net income was $7,095 million, up 25%. Non-GAAP net income was $7,493 million. Source
  • Full-year revenue range raised: The 2026 revenue range rose to $85.0 billion to $87.0 billion from $82 billion to $85 billion. The non-GAAP EPS range is now $35.50 to $36.50, with the top end lowered. Source

Regions and pricing

  • U.S. revenue up 33%: U.S. revenue rose to $14.4 billion on 37% volume growth, with realized prices down 3%. Excluding rebate and discount adjustments, U.S. price would have fallen about 9%. Source
  • Ex-U.S. revenue up 80%: Revenue outside the U.S. rose to $8.6 billion, with volume up 113%, mostly on Mounjaro. Realized prices fell 36%, mainly because Mounjaro was added to China's NRDL. Jardiance included a $250 million milestone. Source
  • Rebate adjustments offset part of decline: Adjustments to rebate and discount estimates, mainly on Trulicity, Zepbound and Mounjaro, partly offset lower U.S. prices. The first half also benefited from sales-based milestones and these adjustments. Source

“Lilly's future, after 150 years, has never been brighter.”

David A. Ricks, Lilly chair and CEO

Products and customers

  • Key Products reached $15.7 billion: Key Products revenue reached $15.7 billion, led by Mounjaro and Zepbound. Key Products in Immunology, Oncology and Neuroscience grew 121% against Q2 2025. Source
  • Mounjaro revenue up 91%: Worldwide Mounjaro revenue was $9.9 billion. U.S. Mounjaro revenue was $4.8 billion, up 45%. Revenue outside the U.S. was $5.2 billion, up 172%, mostly on volume growth. Source
  • Zepbound U.S. revenue up 44%: U.S. Zepbound revenue was $4.9 billion. Lower realized prices reflected previously announced cash-pay price reductions, partly offset by rebate and discount adjustments. Source
  • Smaller products reported growth: Ebglyss revenue was $201 million, up 131%. Kisunla was $167 million, against $49 million. Omvoh was $102 million, up 36%. Inluriyo ($75 million) and Foundayo ($98 million) had no prior-year revenue. Source
  • Foundayo and Zepbound coverage expanded: The release says Foundayo and Zepbound are now covered for millions of Americans. It also lists a Medicare Part D patient explainer for both products. Source

Costs and margins

  • Gross margin 85.8% of revenue: Gross margin rose 50% to $19.7 billion. Non-GAAP gross margin was 86.3% of revenue. Management cited improved cost of production and favorable product mix, partly offset by lower realized prices. Source
  • R&D rose 14% to $3.8 billion: R&D was 17% of revenue, reflecting continued investment in early and late-stage portfolio work. Six-month R&D was $7,329 million, up 21%. Source
  • Promotion lifted selling costs 25%: Marketing, selling and administrative costs rose to $3.4 billion, mainly from promotion supporting ongoing and planned launches. Source

Pipeline and regulatory progress

  • Retatrutide data package now complete: Three additional Phase 3 obesity trials of retatrutide were positive. The company says the clinical data package is complete for global registrations in obesity, sleep apnea and knee pain. Source
  • Ebglyss gets eight-week maintenance dosing: The FDA approved Ebglyss for one maintenance dose every eight weeks in moderate-to-severe atopic dermatitis. Source
  • Jaypirca approved in Europe for CLL: The European Commission approved Jaypirca as monotherapy for adults with chronic lymphocytic leukemia across all lines of therapy. Source
  • Orforglipron type 2 diabetes submitted: A U.S. submission for orforglipron in type 2 diabetes was made in the quarter. Foundayo's obesity approval came earlier, in Q1. Source
  • Olomorasib and VERVE-102 updates: Olomorasib received Breakthrough Therapy designation for previously treated KRAS G12C pancreatic cancer. VERVE-102 reduced LDL-C by up to 62% after a single dose. Source

Business development and acquisitions

  • Four Q2 acquisitions completed: Orna Therapeutics, Ajax Therapeutics, Centessa Pharmaceuticals and Kelonia Therapeutics were completed in Q2. The Orna and Ajax deals primarily drove the $2.8 billion acquired IPR&D charge. Source
  • Three infectious disease acquisitions: After June 30, the company completed three acquisitions to build an infectious disease portfolio. The release does not name them. Source
  • AtaiBeckley acquisition agreed: Lilly agreed to acquire AtaiBeckley for treatment-resistant depression and other mental health conditions. The release gives no completion date. Source

Charges, tax and excluded items

  • $2.8 billion IPR&D charges in Q2: Acquired IPR&D charges were $2.8 billion, against $154 million a year earlier. Six-month charges were $3,360 million. Reported and non-GAAP EPS both include these charges. Source
  • Impairment and integration charge of $703 million: The $703 million charge was mainly accelerated vesting of employee equity awards and acquisition and integration costs. The six-month special charges of $982 million also include litigation matters. Source
  • Tax rate rose on non-deductible IPR&D: The reported effective tax rate was 23.3%, against 16.5% a year earlier. The non-GAAP effective tax rate was 22.2%. Source
  • Equity gains excluded from non-GAAP EPS: Net gains on equity securities were $0.39 per share in Q2, against $0.09 a year earlier. Non-GAAP EPS removes these gains. Source

Capital and shareholder returns

  • Indiana manufacturing commitment: The company committed $4.5 billion more to expand Indiana manufacturing sites. It also opened its first dedicated genetic medicine facility. Source
  • Dividend per share up 15%: Dividends paid were $1.73 per share in Q2, against $1.50. Year to date, dividends were $3.46 per share, against $3.00. Source
  • Diluted share count lower: Weighted-average diluted shares were 893.7 million in Q2, against 899.8 million a year earlier. Source
  • Net interest expense increased: Net interest expense was $274 million in Q2, against $209 million a year earlier. Six-month net interest expense was $527 million. Source

Coming up, as management said on 5 August 2026

  • Retatrutide filing planned for Q1 2027: The company plans to submit a Biologics License Application to the FDA for retatrutide in the first quarter of 2027. Source
  • Investment Community Meeting in December: The company announced a planned Investment Community Meeting for December 7, 2026, in its Q1 release.

Figures management reported

FigureReported
Mounjaro revenue (Q2, worldwide) Source$9.9 billion
Zepbound revenue (Q2, U.S.) Source$4.9 billion
Ebglyss revenue (Q2) Source$201 million
Jaypirca revenue (Q2) Source$192 million
Kisunla revenue (Q2) Source$167 million
Omvoh revenue (Q2) Source$102 million
Inluriyo revenue (Q2) Source$75 million
Foundayo revenue (Q2) Source$98 million
R&D expense (Q2) Source$3.8 billion, 17% of revenue
Approval: Ebglyss maintenance dosing (U.S.) Sourceone dose every eight weeks
Approval: Jaypirca in CLL (European Union) Sourcemonotherapy, all lines of therapy
Trial readouts: retatrutide Phase 3 obesity Sourcethree additional trials positive

Risks management discussed

  • Financial: Non-deductible acquired IPR&D charges raised the Q2 effective tax rate to 23.3%. Source
  • Regulatory: Mounjaro's addition to China's NRDL lowered realized prices outside the U.S. Source
  • External: Realized U.S. prices would have fallen about 9% excluding rebate and discount adjustments. Source
  • Operational: Acquisition integration and employee equity vesting drove the $703 million special charge. Source

Earlier plans management reported on

  • Met: The Q1 release described these as agreements to acquire. The Q2 release reports all four as completed. Source
  • Not stated: The company says it has committed the amount. The release gives no timing for spending. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.