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Ionis Pharmaceuticals (IONS) Q4 FY2022 earnings: revenue $152 million, down 65.5% on the year

Ionis Pharmaceuticals Inc. (IONS) reported revenue of $152 million for Q4 FY2022, the quarter ended 31 December 2022, down 65.5% on the same quarter a year earlier. Net income was -$52 million, and diluted earnings per share $-0.37. The figures are the company's own, from the 10-K it filed with the SEC on 22 February 2023.

Revenue$152 milliondown 65.5%
Net income-$52 million
Diluted EPS$-0.37
QuarterQ4 FY2022ended 31 December 2022

The quarter, against the one before and a year earlier

LineQ4 FY2022Q3 FY2022Q4 FY2021Change on the year
Revenue152160440-65.5%
Cost of revenue3.71.52.2+65.5%
Gross profit148158438-66.1%
Gross margin97.6%99.1%99.5%
Selling, general and administrative48.034.437.6+27.5%
Operating income-208-59.2221n/a
Operating margin-137.0%-37.0%50.1%
Interest expense1.72.12.2-22.7%
Pre-tax income-44.3-46.7225n/a
Income tax8.10.30.3+2609.0%
Effective tax raten/an/a0.1%
Net income-52.4-47.0225n/a
Net margin-34.5%-29.4%51.0%
Diluted EPS-$0.37-$0.33$1.41n/a
$ million except per share.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow and capital returned

LineQ4 FY2022Q3 FY2022Q4 FY2021Change on the year
Operating cash flow-200-24.4204n/a
Capital expenditure4.15.52.5+65.4%
Free cash flow-204-30.0201n/a
Free cash flow margin-134.5%-18.8%45.7%
Cash from investing212-18495.1+123.1%
Cash from financing-51.01.8-62.5n/a
Depreciation and amortisation3.64.44.4-18.0%
Share-based compensation25.723.822.3+15.4%
Buybacksn/an/a0.0n/a
Diluted shares, weightedn/a142m160mn/a
Shares outstanding at period end142m142m141m+0.6%

Cash flow lines for the quarter; where the company files them year to date, the quarter is the difference between two filings.

Balance sheet at quarter end

LineQ4 FY2022Q3 FY2022Q4 FY2021Change on the year
Shareholders' equity573594772-25.8%
Debt1,1941,2541,221-2.2%
Operating lease liabilities179n/a19.4+820.9%
Other liabilities588573599-1.9%
Total liabilities and equity2,5342,4222,612-3.0%
Fixed assets74.3181178-58.3%
Intangible assetsn/a29.629.0n/a
Investments2,2202,2461,881+18.0%
Cash and equivalents276315869-68.2%
Inventory22.020.624.8-11.2%
Total assets2,5342,4222,612-3.0%

Questions

What was Ionis Pharmaceuticals' revenue in Q4 FY2022?

Ionis Pharmaceuticals (IONS) reported revenue of $152 million for Q4 FY2022, the quarter ended 31 December 2022, down 65.5% on the same quarter a year earlier.

How much did Ionis Pharmaceuticals earn in Q4 FY2022?

Net loss for Q4 FY2022 was $52 million, and the diluted loss per share $0.37.

When did Ionis Pharmaceuticals report Q4 FY2022 results?

Ionis Pharmaceuticals filed its 10-K for the quarter ended 31 December 2022 with the SEC on 22 February 2023.

Quarterly results, the last 20 quarters

Q3 FY2021Q4 FY2021Q1 FY2022Q2 FY2022Q3 FY2022Q4 FY2022Q1 FY2023Q2 FY2023Q3 FY2023Q4 FY2023Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024Q1 FY2025Q2 FY2025Q3 FY2025Q4 FY2025Q1 FY2026Q2 FY2026
Revenue133440142134160152131188144325119225134227132452157203246268
Cost of revenue3.12.24.24.71.53.71.32.52.23.12.24.21.13.81.54.22.38.03.02.7
Gross profit130438138129158148129186142321117221133223130448154195243265
Gross margin98%99%97%96%99%98%99%99%98%99%98%98%99%98%99%99%99%96%99%99%
SG&A31.137.634.133.834.448.045.546.170.071.052.665.161.688.176.290.696.8130150150
Operating income-85.8221-57.5-85.5-59.2-208-114-90.2-143-6.1-150-66.1-149-111-147140-160-214-117-102
Operating margin-65%50%-41%-64%-37%-137%-87%-48%-99%-2%-125%-29%-111%-49%-112%31%-102%-105%-48%-38%
Interest expense2.32.22.12.12.11.71.62.34.24.64.24.54.24.24.14.14.24.85.24.6
Pre-tax income-83.8225-64.1-103-46.7-44.3-113-77.4-141-2.8-143-66.2-144-107-147124-128-228-92.3-113
Tax raten/a0%n/an/an/an/an/an/an/an/an/an/an/an/an/a-0%n/an/an/an/a
Net income-82.5225-65.2-105-47.0-52.4-124-85.3-147-9.3-143-66.3-140-104-147124-129-229-92.5-115
Net margin-62%51%-46%-79%-29%-35%-95%-45%-102%-3%-120%-29%-105%-46%-112%27%-82%-113%-38%-43%
Diluted EPS-$0.58$1.41-$0.46-$0.74-$0.33-$0.37-$0.87-$0.60-$1.03-$0.06-$0.98-$0.45-$0.95-$0.66-$0.93$0.70-$0.80-$1.41-$0.56-$0.69
Operating cash flow-55.6204-31.6-18.1-24.4-200-134-97.4-10932.9-150-120-115-116-151151-131-138-793566
Capital expenditure3.32.52.73.35.54.110.512.02.1n/a4.56.29.125.512.612.35.321.321.816.1
Free cash flow-58.9201-34.4-21.4-30.0-204-144-109-111n/a-154-126-124-142-163139-137-159-815549
Buybacks0.00.0n/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/a
Shares outstanding141m141m142m142m142m142m143m143m143m144m146m146m158m158m159m159m161m163m166m166m
Filing10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q
Each quarter as filed, linked to its filing.
Read moreMoney is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

10-K for the period ended 31 December 2022, filed 22 February 2023: the filing.