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Ionis Pharmaceuticals (IONS) Q4 FY2021 earnings: revenue $440 million, up 51.6% on the year

Ionis Pharmaceuticals Inc. (IONS) reported revenue of $440 million for Q4 FY2021, the quarter ended 31 December 2021, up 51.6% on the same quarter a year earlier. Net income was $225 million, and diluted earnings per share $1.41. The figures are the company's own, from the 10-K it filed with the SEC on 25 February 2022.

Revenue$440 millionup 51.6%
Net income$225 million
Diluted EPS$1.41
QuarterQ4 FY2021ended 31 December 2021

The quarter, against the one before and a year earlier

LineQ4 FY2021Q3 FY2021A year earlierChange on the year
Revenue440133n/an/a
Cost of revenue2.23.1n/an/a
Gross profit438130n/an/a
Gross margin99.5%97.7%n/a
Selling, general and administrative37.631.1n/an/a
Operating income221-85.8n/an/a
Operating margin50.1%-64.5%n/a
Interest expense2.22.3n/an/a
Pre-tax income225-83.8n/an/a
Income tax0.3-1.3n/an/a
Effective tax rate0.1%n/an/a
Net income225-82.5n/an/a
Net margin51.0%-62.0%n/a
Diluted EPS$1.41-$0.58n/an/a
$ million except per share.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow and capital returned

LineQ4 FY2021Q3 FY2021A year earlierChange on the year
Operating cash flow204-55.6n/an/a
Capital expenditure2.53.3n/an/a
Free cash flow201-58.9n/an/a
Free cash flow margin45.7%-44.3%n/a
Cash from investing95.1122n/an/a
Cash from financing-62.51.5n/an/a
Depreciation and amortisation4.44.3n/an/a
Share-based compensation22.330.5n/an/a
Buybacks0.00.0n/an/a
Diluted shares, weighted160m141mn/an/a
Shares outstanding at period end141m141mn/an/a

Cash flow lines for the quarter; where the company files them year to date, the quarter is the difference between two filings.

Balance sheet at quarter end

LineQ4 FY2021Q3 FY2021A year earlierChange on the year
Shareholders' equity772531n/an/a
Debt1,2211,282n/an/a
Operating lease liabilities19.4n/an/an/a
Other liabilities599602n/an/a
Total liabilities and equity2,6122,415n/an/a
Fixed assets178180n/an/a
Intangible assets29.030.0n/an/a
Investments1,8811,354n/an/a
Cash and equivalents869633n/an/a
Inventory24.822.9n/an/a
Other assetsn/a195n/an/a
Total assets2,6122,415n/an/a

Questions

What was Ionis Pharmaceuticals' revenue in Q4 FY2021?

Ionis Pharmaceuticals (IONS) reported revenue of $440 million for Q4 FY2021, the quarter ended 31 December 2021, up 51.6% on the same quarter a year earlier.

How much did Ionis Pharmaceuticals earn in Q4 FY2021?

Net income for Q4 FY2021 was $225 million, and diluted earnings per share $1.41.

When did Ionis Pharmaceuticals report Q4 FY2021 results?

Ionis Pharmaceuticals filed its 10-K for the quarter ended 31 December 2021 with the SEC on 25 February 2022.

Quarterly results, the last 20 quarters

Q3 FY2021Q4 FY2021Q1 FY2022Q2 FY2022Q3 FY2022Q4 FY2022Q1 FY2023Q2 FY2023Q3 FY2023Q4 FY2023Q1 FY2024Q2 FY2024Q3 FY2024Q4 FY2024Q1 FY2025Q2 FY2025Q3 FY2025Q4 FY2025Q1 FY2026Q2 FY2026
Revenue133440142134160152131188144325119225134227132452157203246268
Cost of revenue3.12.24.24.71.53.71.32.52.23.12.24.21.13.81.54.22.38.03.02.7
Gross profit130438138129158148129186142321117221133223130448154195243265
Gross margin98%99%97%96%99%98%99%99%98%99%98%98%99%98%99%99%99%96%99%99%
SG&A31.137.634.133.834.448.045.546.170.071.052.665.161.688.176.290.696.8130150150
Operating income-85.8221-57.5-85.5-59.2-208-114-90.2-143-6.1-150-66.1-149-111-147140-160-214-117-102
Operating margin-65%50%-41%-64%-37%-137%-87%-48%-99%-2%-125%-29%-111%-49%-112%31%-102%-105%-48%-38%
Interest expense2.32.22.12.12.11.71.62.34.24.64.24.54.24.24.14.14.24.85.24.6
Pre-tax income-83.8225-64.1-103-46.7-44.3-113-77.4-141-2.8-143-66.2-144-107-147124-128-228-92.3-113
Tax raten/a0%n/an/an/an/an/an/an/an/an/an/an/an/an/a-0%n/an/an/an/a
Net income-82.5225-65.2-105-47.0-52.4-124-85.3-147-9.3-143-66.3-140-104-147124-129-229-92.5-115
Net margin-62%51%-46%-79%-29%-35%-95%-45%-102%-3%-120%-29%-105%-46%-112%27%-82%-113%-38%-43%
Diluted EPS-$0.58$1.41-$0.46-$0.74-$0.33-$0.37-$0.87-$0.60-$1.03-$0.06-$0.98-$0.45-$0.95-$0.66-$0.93$0.70-$0.80-$1.41-$0.56-$0.69
Operating cash flow-55.6204-31.6-18.1-24.4-200-134-97.4-10932.9-150-120-115-116-151151-131-138-793566
Capital expenditure3.32.52.73.35.54.110.512.02.1n/a4.56.29.125.512.612.35.321.321.816.1
Free cash flow-58.9201-34.4-21.4-30.0-204-144-109-111n/a-154-126-124-142-163139-137-159-815549
Buybacks0.00.0n/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/an/a
Shares outstanding141m141m142m142m142m142m143m143m143m144m146m146m158m158m159m159m161m163m166m166m
Filing10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q10-Q10-K10-Q10-Q
Each quarter as filed, linked to its filing.
Read moreMoney is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and the share count are as they are. Free cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Cash flow lines filed year to date are the difference between two filings. Shares outstanding are at the period end where the balance sheet tags them, otherwise the count on the filing's cover page. A derived fourth-quarter EPS is left blank when a split in the year makes the arithmetic meaningless.

10-K for the period ended 31 December 2021, filed 25 February 2022: the filing.