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Stock research / United States / INSM / Insiders

Insmed Inc. insider trading

In twelve months insiders at Insmed bought nothing and sold $167M on the open market; 130 of the 169 sales were under plans set months before.

Bought on the open marketNonein twelve months
Sold on the open market$167M169 sales
Sales set in advance130 of 169under Rule 10b5-1 plans
Pay taken in stockNone
New to this? How to read this page
  1. Insiders are the people who run the company: officers, directors and owners of 10% or more. They must report a trade on Form 4 within two business days.
  2. A purchase on the open market is the strongest sign: the insider spent their own money.
  3. A sale under a trading plan (Rule 10b5-1) says little: its dates were fixed months before. Sales outside a plan say more, but insiders sell for many reasons, such as taxes or a house.
  4. Grants, option exercises and shares held back for tax are left out.
  5. What is a Form 4? · Form 4 codes

What kind of trades

Insiders only sold: 169 sales worth $167M, and 130 of them were under plans set months before, which say little.

Purchasebought with their own money
Pay in stock, own choiceowed cash, chose shares
Sale outside a planthe insider picked the day
Sale under a plandates fixed months before
Says littlecompany plans, board pay, cash units
Bought
none
Sold
39130 under a plan

Every Form 4 line of the last twelve months, counted by kind. The grades come from the filing itself: whether the insider paid cash, whether a plan set the date, whether pay was taken in stock by choice.

Insider trades on the share price

last twelve months

72 marks over twelve months, each in its grade: solid for the stronger signs, hollow or grey for the ones that say little.

PurchasePay in stock, own choiceSale outside a planSale under a planSays little

The blue line is the daily close over twelve months. Each mark is one insider's trades on one day, on that day's price, sized by dollar value. Solid marks are the stronger signs; hollow and grey marks say little. Hover or tap a mark for who, how much and why.

Trades worth a closer look

A purchase stands out when two or more of these hold: a senior insider, several insiders buying within 90 days, a fall of 10% or more in the three months before, or over $1 million. A sale outside a plan is judged the same way. These are the Feed's rules.

Who traded

dollars, twelve months

10 insiders traded. The most: Adsett Roger, sale outside a plan $33.8M; sale under a plan $14.5M.

One row per insider, sold to the left and bought to the right, split by grade: the paler part of a bar is the part that says little.

How it compares

every company on the site

Open-market sales, twelve months

Open-market purchases, twelve months

    The bar ranks every company on the site from the lowest on the left to the highest on the right, in three equal thirds; the small figures under it are the values where each third starts, and the black tick is the middle company. The orange dot is this company; the grey ticks are the other companies in its industry (hover or tap for names). A hatched block is companies tied at none.

    Every Form 4 line

    Purchase: bought on the open market with their own moneyTook pay in stock, own choice: owed cash, chose shares instead; a softer signSale: sold on the open market, not under a plan set in advanceSale, trading plan: under a Rule 10b5-1 plan set up months before, so the date was fixed in advanceGrey lines: plan purchases, pay in stock taken by the whole board or under a company plan, and units paid in cash; they say little about the insider's own view
    TradedInsiderRoleTypeSharesPriceValueFiling
    9 September 2026Brennan David RDirectorSaleafter a 40% rise over three months · 39% below its one-year high · Form 144 notice 10 September 202625,000$124.00$3.1 millionForm 4
    17 August 2026Sharoky Melvin Md, by Padonia, LLCDirectorSaleafter a 20% rise over three months · 39% below its one-year high · Form 144 notice 17 August 20265,000$127.53$637,650Form 4
    10 August 2026Adsett RogerChief Operating OfficerSaleafter a 30% rise over three months · 36% below its one-year high · Form 144 notice 10 August 2026239,850$133.27$32.0 millionForm 4
    6 August 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 August 20268,895$127.00$1.1 millionForm 4
    6 August 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 August 202618,278$129.40$2.4 millionForm 4
    23 July 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 23 July 20264,828$105.62$509,933Form 4
    23 July 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 23 July 20265,872$106.43$624,957Form 4
    9 July 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 July 20265,005$116.55$583,333Form 4
    9 July 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 July 20262,335$117.62$274,643Form 4
    9 July 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 July 20263,359$118.52$398,109Form 4
    6 July 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 July 20264,854$109.02$529,183Form 4
    6 July 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 July 20267,448$110.60$823,749Form 4
    25 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 25 June 202612,091$102.34$1.2 millionForm 4
    25 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 25 June 20261,836$103.10$189,292Form 4
    25 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 25 June 20263,723$104.28$388,234Form 4
    25 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 25 June 20262,456$105.27$258,543Form 4
    25 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 25 June 20261,292$106.27$137,301Form 4
    22 June 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 22 June 20261,806$95.82$173,051Form 4
    8 June 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 8 June 20266,515$94.03$612,605Form 4
    5 June 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 5 June 20261,858$103.78$192,823Form 4
    3 June 2026Adsett RogerChief Operating OfficerSaleafter a 31% fall over three months · 51% below its one-year high · Form 144 notice 3 June 20262,370$102.27$242,380Form 4
    3 June 2026Bonstein SaraChief Financial OfficerSaleafter a 31% fall over three months · 51% below its one-year high · Form 144 notice 3 June 20262,404$102.27$245,857Form 4
    3 June 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 31% fall over three months · 51% below its one-year high · Form 144 notice 3 June 20262,159$102.27$220,801Form 4
    3 June 2026Lewis WilliamChair and CEOSaleafter a 31% fall over three months · 51% below its one-year high · Form 144 notice 3 June 20267,605$102.27$777,763Form 4
    3 June 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 June 20262,566$102.27$262,425Form 4
    22 May 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 22 May 20266,149$108.47$666,982Form 4
    18 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 May 20265,753$105.32$605,906Form 4
    18 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 May 202611,836$106.39$1.3 millionForm 4
    18 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 May 20267,975$106.97$853,086Form 4
    14 May 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 14 May 202610,479$117.54$1.2 millionForm 4
    13 May 2026Bonstein SaraChief Financial OfficerSaleafter a 21% fall over three months · 44% below its one-year high · Form 144 notice 13 May 20268,272$116.18$961,041Form 4
    13 May 2026Adsett RogerChief Operating OfficerSaleafter a 21% fall over three months · 44% below its one-year high · Form 144 notice 13 May 20265,837$116.18$678,143Form 4
    13 May 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 14 May 20264,470$112.76$504,037Form 4
    13 May 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 14 May 20263,384$116.18$393,153Form 4
    13 May 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 21% fall over three months · 44% below its one-year high · Form 144 notice 13 May 20264,109$116.18$477,384Form 4
    13 May 2026Lewis WilliamChair and CEOSaleafter a 21% fall over three months · 44% below its one-year high · Form 144 notice 13 May 202613,283$116.18$1.5 millionForm 4
    11 May 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 11 May 202612,119$100.35$1.2 millionForm 4
    11 May 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 11 May 2026830$101.18$83,979Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 2026433$134.18$58,100Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 2026599$135.18$80,973Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 20265,318$137.01$728,619Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 20262,721$137.86$375,117Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 20261,247$139.09$173,445Form 4
    4 May 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 May 2026381$139.60$53,188Form 4
    16 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 16 April 20262,246$142.99$321,156Form 4
    16 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 16 April 20265,373$143.81$772,691Form 4
    16 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 16 April 20262,255$144.66$326,208Form 4
    16 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 16 April 2026825$145.79$120,277Form 4
    6 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 6 April 2026787$161.73$127,282Form 4
    6 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 6 April 20268,478$163.23$1.4 millionForm 4
    6 April 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 6 April 20261,434$164.01$235,190Form 4
    1 April 2026Adsett RogerChief Operating OfficerSaletrading plan set in advance · Form 144 notice 1 April 20266,715$163.18$1.1 millionForm 4
    1 April 2026Adsett RogerChief Operating OfficerSaletrading plan set in advance · Form 144 notice 1 April 202619,001$164.11$3.1 millionForm 4
    1 April 2026Adsett RogerChief Operating OfficerSaletrading plan set in advance · Form 144 notice 1 April 202662,344$164.95$10.3 millionForm 4
    30 March 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 30 March 202619,638$150.98$3.0 millionForm 4
    19 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 March 20261,629$142.17$231,595Form 4
    19 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 March 20264,537$143.42$650,697Form 4
    19 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 March 20264,533$144.11$653,251Form 4
    5 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 5 March 20262,083$144.23$300,431Form 4
    5 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 5 March 20262,589$145.27$376,104Form 4
    5 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 5 March 20263,899$146.66$571,827Form 4
    5 March 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 5 March 20262,128$147.54$313,965Form 4
    24 February 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 24 February 20264,852$153.93$746,868Form 4
    24 February 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 24 February 20264,151$155.06$643,654Form 4
    24 February 2026Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 24 February 202615,771$156.53$2.5 millionForm 4
    19 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 February 20261,988$149.17$296,550Form 4
    19 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 February 20261,891$150.10$283,839Form 4
    19 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 February 20263,413$151.12$515,773Form 4
    19 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 February 20262,377$151.92$361,114Form 4
    19 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 19 February 20261,030$153.38$157,981Form 4
    9 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 February 20264,888$147.17$719,367Form 4
    9 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 February 20267,221$148.02$1.1 millionForm 4
    9 February 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 9 February 20261,287$148.83$191,544Form 4
    5 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 5 February 2026869$152.44$132,470Form 4
    3 February 2026Adsett RogerChief Operating OfficerSaleafter a 14% fall over three months · 26% below its one-year high · Form 144 notice 3 February 2026791$156.17$123,530Form 4
    3 February 2026Bonstein SaraChief Financial OfficerSaleafter a 14% fall over three months · 26% below its one-year high · Form 144 notice 3 February 2026748$156.34$116,942Form 4
    3 February 2026Lewis WilliamChair and CEOSaleafter a 14% fall over three months · 26% below its one-year high · Form 144 notice 3 February 20263,009$156.34$470,427Form 4
    3 February 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 14% fall over three months · 26% below its one-year high · Form 144 notice 3 February 2026640$156.27$100,013Form 4
    3 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 2026795$155.77$123,837Form 4
    2 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 2026563$152.06$85,610Form 4
    2 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 2026928$153.16$142,132Form 4
    2 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 20263,349$154.56$517,621Form 4
    2 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 20263,042$155.46$472,909Form 4
    2 February 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 3 February 2026100$156.86$15,686Form 4
    20 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 20 January 20261,006$156.80$157,741Form 4
    20 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 20 January 20261,243$158.37$196,854Form 4
    20 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 20 January 20265,967$158.99$948,693Form 4
    20 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 20 January 20262,229$159.85$356,306Form 4
    20 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 20 January 2026254$160.70$40,818Form 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 20263,974$167.73$666,559Form 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 20267,176$168.63$1.2 millionForm 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 20266,996$169.57$1.2 millionForm 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 2026160$170.24$27,238Form 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 2026297$171.31$50,879Form 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 2026297$172.36$51,191Form 4
    12 January 2026Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 12 January 2026315$174.86$55,081Form 4
    9 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 8 January 20261,887$186.19$351,341Form 4
    8 January 2026Adsett RogerChief Operating OfficerSaleafter a 4% rise over three months · 19% below its one-year high · Form 144 notice 8 January 20262,059$174.17$358,616Form 4
    8 January 2026Bonstein SaraChief Financial OfficerSaleafter a 4% rise over three months · 19% below its one-year high · Form 144 notice 8 January 20261,447$174.17$252,024Form 4
    8 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 8 January 20261,660$173.87$288,624Form 4
    8 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 8 January 20263,251$174.17$566,227Form 4
    8 January 2026Lewis WilliamChair and CEOSaleafter a 4% rise over three months · 19% below its one-year high · Form 144 notice 8 January 20263,223$174.17$561,350Form 4
    8 January 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 4% rise over three months · 19% below its one-year high · Form 144 notice 8 January 20261,053$174.17$183,401Form 4
    7 January 2026Adsett RogerChief Operating OfficerSaleafter a 9% rise over three months · 17% below its one-year high · Form 144 notice 8 January 2026802$175.07$140,406Form 4
    7 January 2026Bonstein SaraChief Financial OfficerSaleafter a 9% rise over three months · 17% below its one-year high · Form 144 notice 8 January 20261,678$175.07$293,767Form 4
    7 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 8 January 20261,434$175.84$252,155Form 4
    7 January 2026Lewis WilliamChair and CEOSaleafter a 9% rise over three months · 17% below its one-year high · Form 144 notice 8 January 20262,357$175.07$412,640Form 4
    7 January 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 9% rise over three months · 17% below its one-year high · Form 144 notice 8 January 2026709$175.07$124,125Form 4
    6 January 2026Adsett RogerChief Operating OfficerSaleafter a 8% rise over three months · 17% below its one-year high · Form 144 notice 7 January 20261,429$173.33$247,689Form 4
    6 January 2026Bonstein SaraChief Financial OfficerSaleafter a 8% rise over three months · 17% below its one-year high · Form 144 notice 7 January 20261,517$173.33$262,942Form 4
    6 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 7 January 20264,783$173.47$829,707Form 4
    6 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 7 January 20262,830$174.21$493,014Form 4
    6 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 7 January 2026957$175.01$167,485Form 4
    6 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 7 January 20261,615$173.33$279,928Form 4
    6 January 2026Lewis WilliamChair and CEOSaleafter a 8% rise over three months · 17% below its one-year high · Form 144 notice 7 January 20264,096$173.33$709,960Form 4
    6 January 2026Smith Michael AlexanderChief Legal OfficerSaleafter a 8% rise over three months · 17% below its one-year high · Form 144 notice 7 January 20261,396$173.33$241,969Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 20262,799$169.29$473,843Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 20263,205$170.61$546,805Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 20262,836$171.19$485,495Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 2026286$171.92$49,169Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 20261,820$173.45$315,679Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 2026655$174.28$114,153Form 4
    5 January 2026Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 6 January 2026702$175.73$123,362Form 4
    2 January 2026Schaeffer Orlov S NicoleChief People Strategy OfficerSaletrading plan set in advance · Form 144 notice 2 January 202631,030$174.28$5.4 millionForm 4
    2 January 2026Schaeffer Orlov S NicoleChief People Strategy OfficerSaletrading plan set in advance · Form 144 notice 2 January 202634,103$175.17$6.0 millionForm 4
    2 January 2026Schaeffer Orlov S NicoleChief People Strategy OfficerSaletrading plan set in advance · Form 144 notice 2 January 202612,832$176.08$2.3 millionForm 4
    2 January 2026Schaeffer Orlov S NicoleChief People Strategy OfficerSaletrading plan set in advance · Form 144 notice 2 January 20269,125$177.17$1.6 millionForm 4
    2 January 2026Schaeffer Orlov S NicoleChief People Strategy OfficerSaletrading plan set in advance · Form 144 notice 2 January 2026200$177.78$35,556Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 2025350$162.26$56,791Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 20251,465$163.19$239,073Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 2025447$164.24$73,415Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 2025697$165.21$115,151Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 20251,783$166.60$297,048Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 20251,431$167.29$239,392Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 20252,175$168.54$366,574Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 20251,938$169.58$328,646Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 2025362$170.26$61,634Form 4
    18 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 18 December 202551$171.20$8,731Form 4
    5 December 2025Sharoky Melvin MdDirectorSaleafter a 41% rise over three months · 4% below its one-year high · Form 144 notice 5 December 202520,000$205.01$4.1 millionForm 4
    4 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 December 20254,516$204.62$924,064Form 4
    4 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 December 20252,222$205.66$456,977Form 4
    4 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 December 20252,921$206.49$603,157Form 4
    4 December 2025Lewis WilliamChair and CEOSaletrading plan set in advance · Form 144 notice 4 December 20251,040$207.42$215,717Form 4
    1 December 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 1 December 20251,450$205.98$298,671Form 4
    1 December 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 1 December 20255,886$207.03$1.2 millionForm 4
    1 December 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 1 December 20251,559$207.73$323,851Form 4
    24 November 2025Anderson Elizabeth MDirectorSaleafter a 61% rise over three months · at its one-year high · Form 144 notice 24 November 20255,000$204.58$1.0 millionForm 4
    17 November 2025Lee LeoDirectorSaleafter a 55% rise over three months · at its one-year high · Form 144 notice 17 November 20253,212$193.51$621,554Form 4
    17 November 2025Lee LeoDirectorSaleafter a 55% rise over three months · at its one-year high · Form 144 notice 17 November 202517,594$194.49$3.4 millionForm 4
    17 November 2025Lee LeoDirectorSaleafter a 55% rise over three months · at its one-year high · Form 144 notice 17 November 202514,944$195.39$2.9 millionForm 4
    17 November 2025Lee LeoDirectorSaleafter a 55% rise over three months · at its one-year high · Form 144 notice 17 November 202524,076$196.61$4.7 millionForm 4
    17 November 2025Lee LeoDirectorSaleafter a 55% rise over three months · at its one-year high · Form 144 notice 17 November 202515,174$197.40$3.0 millionForm 4
    14 November 2025Anderson Elizabeth MDirectorSaleafter a 51% rise over three months · at its one-year high · Form 144 notice 13 November 202510,000$195.87$2.0 millionForm 4
    12 November 2025Schaeffer Orlov S NicoleChief People Strategy OfficerSaleafter a 58% rise over three months · at its one-year high · Form 144 notice 12 November 20254,078$192.45$784,811Form 4
    12 November 2025Schaeffer Orlov S NicoleChief People Strategy OfficerSaleafter a 58% rise over three months · at its one-year high · Form 144 notice 12 November 20256,575$193.64$1.3 millionForm 4
    12 November 2025Schaeffer Orlov S NicoleChief People Strategy OfficerSaleafter a 58% rise over three months · at its one-year high · Form 144 notice 12 November 202519,183$194.44$3.7 millionForm 4
    12 November 2025Schaeffer Orlov S NicoleChief People Strategy OfficerSaleafter a 58% rise over three months · at its one-year high · Form 144 notice 12 November 2025164$195.88$32,124Form 4
    11 November 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 12 November 20255,467$188.38$1.0 millionForm 4
    11 November 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 12 November 202512,224$189.36$2.3 millionForm 4
    11 November 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 12 November 202510,622$190.33$2.0 millionForm 4
    11 November 2025Flammer Martina M.D.Chief Medical OfficerSaletrading plan set in advance · Form 144 notice 12 November 20252,913$191.04$556,500Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20251,342$181.01$242,915Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20257,619$181.88$1.4 millionForm 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20254,286$182.60$782,624Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20254,032$183.92$741,565Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20253,243$184.91$599,663Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20253,636$185.93$676,041Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20251,572$187.15$294,200Form 4
    3 November 2025Smith Michael AlexanderChief Legal OfficerSaletrading plan set in advance · Form 144 notice 3 November 20251,400$187.97$263,158Form 4
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