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Harmony Biosciences Holdings (HRMY) FY2025 results: revenue $868 million, up 21.5% on the year

Harmony Biosciences Holdings, Inc. (HRMY) reported revenue of $868 million for fiscal 2025, the year ended 31 December 2025, up 21.5% on the year before. Net income was $159 million, up 9.1%, and diluted earnings per share $2.71. The figures are the company's own, from the 10-K it filed with the SEC on 24 February 2026.

Revenue
$868 million
+21.5% on the year
FY2019FY2025
Operating margin
24.0%
26.7% a year earlier
FY2019FY2025
Net income
$159 million
+9.1% on the year
FY2019FY2025
Diluted EPS
$2.71
+8.0% on the year
FY2019FY2025

this yearthe year beforeHover a bar for its figure.

The year in brief

What management said about the year

Guidance figures: 1 kept.

  • Q4 WAKIX revenue rose 21%: WAKIX net product revenue was $243.8 million for the quarter, compared with $201.3 million a year earlier, up 21%.
  • Full-year revenue rose about 22%: Full-year 2025 net product revenue was $868.5 million, compared with $714.7 million in 2024, growth of about 22%.
  • Patients on WAKIX rose about 400: Average patients on WAKIX rose by about 400 to about 8,500 in Q4 2025, the third consecutive quarter of about 400 or more additions.
  • Q4 GAAP net income fell: Q4 GAAP net income was $22.5 million, or $0.38 per diluted share, compared with $49.5 million, or $0.85 per diluted share, in Q4 2024.
  • Promotion began on pediatric approval: After the pediatric cataplexy approval, the commercial team started full promotional efforts immediately, according to management.
Read the Q4 FY2025 earnings call summary

The four quarters: Q1 FY2025 · Q2 FY2025 · Q3 FY2025 · Q4 FY2025

Income statement (profit and loss)

$ millionFY2025FY2024FY2023On the yearLast 8 years
Revenue868715582+21.5%
Cost of revenue198157121+26.5%
Gross profit670558461+20.1%
Gross margin77.2%78.1%79.2%
Research and development19014676.1+30.0%
Operating income208191192+9.2%
Operating margin24.0%26.7%33.0%
Interest expense14.617.523.8-16.3%
Pre-tax income215192173+12.1%
Income tax56.446.344.5+21.7%
Effective tax rate26.2%24.1%25.7%
Net income159145129+9.1%
Net margin18.3%20.4%22.1%
Diluted EPS$2.71$2.51$2.13+8.0%
$ million except per share.
Read moreFree cash flow is operating cash flow less capital expenditure; the effective tax rate is income tax over pre-tax income; margins are the line over revenue. Gross profit is revenue less cost of revenue, and operating income is revenue less the company's own total costs, where the statement does not print those lines. Those four are arithmetic on the filed numbers; everything else is as filed. Money is in $ million as the company files it, or in $ billion by the switch above the tables; per share figures and share counts are as they are.

Cash flow

$ millionFY2025FY2024FY2023On the yearLast 8 years
Operating cash flow348220219+58.4%
Capital expenditure0.31.20.3-73.1%
Free cash flow348219219+59.1%
Free cash flow margin40.1%30.6%37.6%
Cash from investing-39.6-67.5-46.4
Cash from financing-9.0-11.0-106
Depreciation and amortisationn/a24.124.4
Share-based compensation44.942.631.7+5.4%
Buybacksn/an/a100
Diluted shares, weighted59m58m60m+1.2%
Shares outstanding at period end58m57m57m+1.0%

Balance sheet

$ millionFY2025FY2024FY2023On the yearLast 8 years
Shareholders' equity870659467+32.0%
Debt164179194-8.7%
Operating lease liabilities4.50.81.1+448.9%
Other liabilities233160150+45.8%
Total liabilities and equity1,272999811+27.3%
Fixed assetsn/a1.30.4
Intangible assets89.4113137-21.1%
Investments130123114+5.6%
Cash and equivalents753453312+66.1%
Receivables96.883.074.1+16.6%
Inventory5.47.25.4-25.6%
Other assets198218169-9.5%
Total assets1,272999811+27.3%

10-K for the year ended 31 December 2025, filed 24 February 2026: the filing.