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Collegium Pharmaceutical, Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 26 February 2026: press release. Guidance figures: 3 kept. The quarter’s numbers.

Key takeaways

  • Quarterly net revenue rose 13%: Product revenues, net were $205.4 million in the 2025 quarter, up 13% from $181.9 million in the 2024 quarter. Source
  • Full-year adjusted EBITDA rose 15%: Adjusted EBITDA for FY 2025 was $460.5 million, up 15% from $401.2 million for FY 2024. Source
  • Jornay PM quarterly revenue up 57%: Jornay PM net revenue was a record $45.9 million in the 2025 quarter, up 57% year-over-year. Source
  • Prescriptions reached an all-time high: Jornay PM prescriptions were over 200,000 in the 2025 quarter, up 16%, and over 760,000 for FY 2025, up 20%. Source
  • Hikma gets exclusive Nucynta AG rights: Hikma holds the exclusive right to sell the Collegium-supplied authorized generics of Nucynta and Nucynta ER in the United States. Source
  • Credit facility closed in December: A $980 million syndicated credit facility closed in December, with part of the proceeds used to repay the remaining $581 million of the previous term loan. Source
  • 2026 guidance reaffirmed: Full-year 2026 guidance for product revenues, Jornay PM revenues and adjusted EBITDA was reaffirmed, with the ranges unchanged. Source

“In our first full year of owning Jornay PM, we grew full-year net revenue by 48% and reached a record number of prescribers in support of our differentiated medicine for the treatment of ADHD.”

Vikram Karnani, President and Chief Executive Officer

Guidance

AreaPeriodFigureAgainst last quarter
Product revenues, net Sourcefull-year 2026$805 to $825 millionKept
Jornay PM revenue, net Sourcefull-year 2026$190 to $200 millionKept
Adjusted EBITDA Sourcefull-year 2026$455 to $475 millionKept

What changed from last quarter

  • New: A $980 million syndicated credit facility closed in December; part of it repaid the remaining $581 million of the previous term loan. Source
  • Ended: The previous $646 million Pharmakon term loan was repaid; the remaining balance was $581 million. Source
  • New: In January, supply and quality agreements were announced with Hikma under the April 2024 authorized generic agreement. Source
  • Guidance kept: Full-year 2026 guidance for product revenues, Jornay PM revenues and adjusted EBITDA is reaffirmed. Source

Results and growth drivers

  • Quarterly net revenue rose 13%: Product revenues, net were $205.4 million in the 2025 quarter, up 13% from $181.9 million in the 2024 quarter. Source
  • Full-year net revenue reached a record: Full-year product revenues, net were $780.6 million, up 24% from $631.4 million, described in the release as record full-year net revenues. Source
  • Full-year adjusted EBITDA rose 15%: Adjusted EBITDA for FY 2025 was $460.5 million, up 15% from $401.2 million for FY 2024. Source
  • Quarterly adjusted EBITDA rose 18%: Adjusted EBITDA was $127.3 million in the 2025 quarter, compared with $107.7 million in the 2024 quarter. Source

Jornay PM demand and prescribers

  • Jornay PM quarterly revenue up 57%: Jornay PM net revenue was a record $45.9 million in the 2025 quarter, up 57% year-over-year. Source
  • Prescriptions reached an all-time high: Jornay PM prescriptions were over 200,000 in the 2025 quarter, up 16%, and over 760,000 for FY 2025, up 20%. Source
  • Prescriber count reached 29,000: 29,000 healthcare providers wrote Jornay PM prescriptions in the 2025 quarter, an all-time high and up 21% year-over-year. Source
  • Real-world evidence work continued: In 2025 the company presented at four scientific congresses and completed four real-world evidence studies; four posters were presented in January. Source

“We remain committed to our capital deployment strategy, prioritizing business development opportunities, opportunistic share repurchases, and paying down debt, all of which are intended to create long-term value.”

Colleen Tupper, Chief Financial Officer

Pain portfolio performance

  • Pain portfolio up 5% in quarter: Pain portfolio net revenues were $159.6 million in the 2025 quarter, up 5%; full-year pain revenues were a record $631.7 million, up 6%. Source
  • Belbuca grew 7% in quarter: Belbuca net revenue was $59.1 million in the 2025 quarter, up 7%, and $221.7 million for FY 2025, up 5%. Source
  • Xtampza ER fell 6% in quarter: Xtampza ER net revenue was $48.6 million in the 2025 quarter, down 6%, and $199.3 million for FY 2025, up 4%. Source
  • Nucynta Franchise grew 15% in quarter: Nucynta Franchise net revenue was $47.9 million in the 2025 quarter, up 15%, and $196.3 million for FY 2025, up 11%. Source

Hikma authorized generic agreements

  • Hikma gets exclusive Nucynta AG rights: Hikma holds the exclusive right to sell the Collegium-supplied authorized generics of Nucynta and Nucynta ER in the United States. Source
  • Collegium shares in AG net profits: Collegium would receive a significant share of AG net profits, which would decline with the number of third-party generic equivalents sold, if any. Source
  • Supply and quality agreements signed: Supply and quality agreements with Hikma were announced in January under the authorized generic arrangement. Source

“Our investments to expand the sales force and sharpen our marketing approach are already fueling additional momentum.”

Vikram Karnani, President and Chief Executive Officer

Costs, margins and earnings

  • Quarterly GAAP operating expenses up 12%: GAAP operating expenses were $67.6 million in the quarter, up 12%; adjusted operating expenses were $57.5 million, up 13%. Source
  • Full-year adjusted operating expenses up 58%: Adjusted operating expenses were $237.3 million for FY 2025, up 58% from $150.6 million, excluding stock-based compensation and other adjustments. Source
  • Full-year GAAP net income lower: GAAP net income was $62.9 million for FY 2025 against $69.2 million for FY 2024; diluted EPS was $1.73 versus $1.86. Source
  • Adjusted EPS of $7.42 for year: Non-GAAP adjusted net income was $289.3 million, or $7.42 adjusted EPS, against $254.8 million and $6.45 for FY 2024. Source

Cash, debt and credit facility

  • Cash from operations $329.3 million: Operating cash flow was $329.3 million for FY 2025 and $123.0 million in the 2025 quarter; cash and marketable securities ended the year at $386.7 million. Source
  • Credit facility closed in December: A $980 million syndicated credit facility closed in December, with part of the proceeds used to repay the remaining $581 million of the previous term loan. Source
  • Facility has three components: The new facility has a five-year $580 million term loan, a $300 million delayed draw term loan and a $100 million revolver. Source
  • Lower interest rate expected: The new facility carries a reduced rate, which management expects to produce meaningful annualized interest savings. Source

Capital returns and business development

  • $25 million of shares repurchased: The CFO said operating cash flows and debt terms improved, and $25 million of shares were repurchased during 2025. Source
  • Undrawn facility tranches available: The delayed draw term loan and revolver are both undrawn and available for general corporate purposes, including future business development. Source
  • Disciplined capital deployment strategy: Management described its strategy as growing the commercial portfolio, with Jornay PM as lead growth driver, and deploying capital in a disciplined way. Source

Strategy and 2026 guidance

  • 2026 guidance reaffirmed: Full-year 2026 guidance for product revenues, Jornay PM revenues and adjusted EBITDA was reaffirmed, with the ranges unchanged. Source
  • Jornay PM and pain growth expected: The CFO expects another year of significant growth for Jornay PM and durable performance from the pain portfolio in 2026. Source
  • Sales force and marketing investment: The CEO said investments in the sales force and marketing approach are already adding momentum to Jornay PM. Source

Coming up, as management said on 26 February 2026

  • Nucynta ER authorized generic launch: Hikma is expected to launch the Nucynta ER authorized generic in the first quarter of 2026. Source
  • Investor conferences through April 2026: The company will present at five investor conferences between March 9 and April 15, 2026, in Miami and virtually. Source

Figures management reported

FigureReported
Jornay PM net revenue, 2025 quarter Source$45.9 million
Jornay PM net revenue, FY 2025 Source$148.9 million
Jornay PM prescriptions, 2025 quarter Sourceover 200,000
Jornay PM prescriptions, FY 2025 Sourceover 760,000
Jornay PM prescribers, 2025 quarter Source29,000
Pain portfolio net revenue, FY 2025 Source$631.7 million
Belbuca net revenue, FY 2025 Source$221.7 million
Xtampza ER net revenue, FY 2025 Source$199.3 million
Nucynta Franchise net revenue, FY 2025 Source$196.3 million

Risks management discussed

  • External: Collegium's share of Nucynta AG net profits would decline as third-party generic equivalents are sold for each product, if any. Source
  • Financial: GAAP results in the guidance period could be materially affected by items the company cannot predict, such as stock-based compensation and acquisition related expenses. Source

Earlier plans management reported on

  • Met: The CEO said the company delivered on its 2025 strategic priorities: Jornay PM growth, pain portfolio durability and capital deployment. Source
  • Not stated: The Hikma supply and quality agreements follow the authorized generic agreement announced in April 2024. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.