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Azenta, Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 21 November 2025: press release. Guidance figures: 2 new. The quarter’s numbers.

Key takeaways

  • Fourth-quarter revenue rose 6%: Revenue was $159 million, up 6%. Organic growth was 4%, mainly from higher Multiomics revenue. Source
  • Adjusted EBITDA rose 29%: Quarterly adjusted EBITDA was $21 million, a 13.0% margin. Full-year adjusted EBITDA was $66 million, an 11.2% margin. Source
  • Multiomics led quarterly growth: Multiomics quarterly revenue rose 11% from $66 million a year earlier, with organic growth of 10%. Source
  • Cash and securities of $546 million: Cash, restricted cash and marketable securities totalled $546 million at fiscal year-end, September 30, 2025. Source
  • Organic growth target of 3% to 5%: Management expects fiscal 2026 organic revenue growth of 3% to 5% after fiscal 2025 organic growth of 3%. Source
  • Margin expansion target of about 300 basis points: Management expects adjusted EBITDA margin expansion of approximately 300 basis points in fiscal 2026, after 310 basis points in fiscal 2025. Source
  • Classification error corrected in prior periods: Costs were misallocated among cost of revenue, R&D and SG&A. Cost of revenue and R&D were understated, and SG&A overstated, by equal amounts. Source

“Fiscal 2025 was a transformative year for Azenta. We achieved 3% core revenue growth and meaningful margin expansion,”

John Marotta, President and Chief Executive Officer

Guidance

AreaPeriodFigureAgainst last quarter
Organic revenue growth Sourcefiscal 20263% to 5%New
Adjusted EBITDA margin expansion Sourcefiscal 2026 relative to fiscal 2025approximately 300 basis pointsNew

What changed from last quarter

  • New guidance: Fiscal 2026 guidance was given in this release: organic revenue growth of 3% to 5% and adjusted EBITDA margin expansion of about 300 basis points. Source
  • New: Prior-period financial statements were revised for an immaterial classification error among cost of revenue, R&D and SG&A. Source

Results and growth drivers

  • Fourth-quarter revenue rose 6%: Revenue was $159 million, up 6%. Organic growth was 4%, mainly from higher Multiomics revenue. Source
  • Full-year revenue rose 4%: Fiscal 2025 revenue was $594 million, up 4%. Organic revenue was up 3%, largely from higher Multiomics revenue. Source
  • Quarter operating income of $2 million: Operating margin was 1.2% for the quarter. The full-year operating loss was $27 million, a margin of (4.5%). Source
  • Adjusted EBITDA rose 29%: Quarterly adjusted EBITDA was $21 million, a 13.0% margin. Full-year adjusted EBITDA was $66 million, an 11.2% margin. Source
  • One-time tax benefit in GAAP results: A one-time $45.6 million tax benefit from a worthless stock deduction on a foreign subsidiary was excluded from non-GAAP results. Source
  • Full-year total diluted EPS was ($1.30): Total diluted EPS for fiscal 2025 was ($1.30), against ($3.10) a year earlier. Continuing operations EPS was $0.52. Source

Segments and regions

  • Multiomics led quarterly growth: Multiomics quarterly revenue rose 11% from $66 million a year earlier, with organic growth of 10%. Source
  • Sample Management organic revenue flat: Sample Management Solutions revenue was $86 million, up 2%. Organic revenue was flat, with Cryogenic Systems lower. Source
  • Full-year Multiomics revenue rose 6%: Multiomics full-year organic growth was 5%, driven by Next Generation Sequencing. Source

“We enter fiscal 2026 in a healthier position, with a more streamlined and accountable structure, with sharper focus on the customer, and growing momentum across the business.”

John Marotta, President and Chief Executive Officer

Products and customers

  • Sequencing and gene synthesis growth in quarter: Quarterly Multiomics growth came from Next Generation Sequencing and Gene Synthesis, while Sanger sequencing revenue declined year over year. Source
  • Full-year Sanger and gene synthesis decline: For fiscal 2025, Next Generation Sequencing growth was partly offset by lower Sanger sequencing and Gene Synthesis revenue. Source
  • Sample Management consumables and storage growth: Full-year growth in Clinical Biostores, Consumables and Instruments and Sample Storage was partly offset by Cryogenic Systems and Automated Stores. Source

Costs, margins and pricing

  • Quarterly gross margin flat at 45.4%: Gross margin was 45.4%, flat year over year. Management cited cost discipline and sales mix, offset by Multiomics costs and volumes. Source
  • Adjusted gross margin down 20 basis points: Adjusted gross margin was 46.7% for the quarter, with higher Multiomics costs and lower volumes as the stated reasons. Source
  • Full-year gross margin up 110 basis points: Full-year gross margin was 45.5%. Adjusted gross margin was 46.9%, up 100 basis points, on product mix and cost reduction. Source
  • Quarterly operating expenses down 4%: Quarterly operating expenses were $70 million, with lower SG&A, transformation and restructuring, partly offset by higher R&D. Source
  • Full-year adjusted operating expenses up 1%: Adjusted operating expenses for fiscal 2025 were $263 million, with higher SG&A partly offset by lower R&D. Source

Cash, capital and cash flow

  • Cash and securities of $546 million: Cash, restricted cash and marketable securities totalled $546 million at fiscal year-end, September 30, 2025. Source
  • Capital spending of $34 million: Capital expenditures were $8 million in the fourth quarter and $34 million for fiscal 2025. Source
  • Operating cash flow rose to $72 million: Net cash from operating activities was $72.2 million for fiscal 2025, against $49.7 million in fiscal 2024. Free cash flow is not stated in this release. Source

Strategy, people and portfolio

  • Simplified organization and Azenta Business System: Management said the organization was simplified and execution strengthened, with improvements in quality, delivery and productivity. Source
  • Transformation costs tied to 2024 plan: Fiscal 2025 transformation costs were $10.4 million, relating to actions under the 2024 cost reduction plan. Source
  • Discontinued operations weighed on total EPS: Discontinued operations reduced diluted EPS by $0.08 in the quarter. Total diluted EPS for the quarter was $1.02. Source

Fiscal 2026 guidance

  • Organic growth target of 3% to 5%: Management expects fiscal 2026 organic revenue growth of 3% to 5% after fiscal 2025 organic growth of 3%. Source
  • Margin expansion target of about 300 basis points: Management expects adjusted EBITDA margin expansion of approximately 300 basis points in fiscal 2026, after 310 basis points in fiscal 2025. Source
  • Guidance given on non-GAAP basis: Forward-looking guidance is non-GAAP only; the company says a GAAP reconciliation is not available without unreasonable effort. Source

Accounting revision and controls

  • Classification error corrected in prior periods: Costs were misallocated among cost of revenue, R&D and SG&A. Cost of revenue and R&D were understated, and SG&A overstated, by equal amounts. Source
  • Other immaterial prior errors also revised: Previously out-of-period immaterial errors were also corrected by revising prior periods presented in this release. Source
  • Internal control effect under evaluation: Management is evaluating the classification error's effect on internal control over financial reporting. Source

Coming up, as management said on 21 November 2025

  • Higher free cash flow expected in fiscal 2026: Management expects higher free cash flow generation in fiscal 2026, alongside 3% to 5% organic growth and about 300 basis points of margin expansion. Source
  • Revision details to follow in 10-K: Further information on the revisions will be provided in the Form 10-K for the fiscal year ended September 30, 2025. Source

Risks management discussed

  • Operational: Higher costs and lower volumes in parts of the Multiomics segment weighed on gross margin in the quarter. Source
  • Demand: Sanger sequencing revenue declined year over year in the quarter, and Sanger and Gene Synthesis declined for the full year. Source
  • Regulatory: Management is still assessing how the classification error affects internal control over financial reporting. Source

Earlier plans management reported on

  • On track: In August, management said it remained on track to meet full-year fiscal 2025 goals.
  • On track: In August, management said the operational turnaround was progressing as planned.

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.