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Stock research / United States / AZN / Year to 31 December 2025

AstraZeneca PLC (AZN) annual results, year to 31 December 2025: revenue USD 58,739 million, from the 20-F

AstraZeneca PLC files a 20-F with the SEC once a year, in US dollars. In the year to 31 December 2025 it reported revenue of USD 58,739 million, up 8.6% on the year before. Its profit attributable to shareholders was USD 10,225 million, up 45.3%, and diluted earnings per share USD 6.54.

The year to 31 December 2025, against the year before

Year toDec 2024Dec 2025
Revenue54,07358,739
Cost of sales10,20710,633
Gross profit43,86648,106
Research and development13,58314,232
Selling, general and administrative19,97719,933
Operating profit10,00313,743
Finance costs1,7421,694
Profit before tax8,69112,402
Income tax1,6502,169
Profit for the year7,04110,233
Profit attributable to shareholders7,03510,225
Filing20-F20-F

USD million, from the 20-F on the SEC's EDGAR, linked in the last row, on the IFRS tags the company filed. A line the company does not file under the standard tag is left out rather than estimated.

Year toDec 2024Dec 2025
Diluted EPS4.506.54
Basic EPS4.546.60
Filing20-F20-F

USD per ordinary share, as filed.

Cash flow

Year toDec 2024Dec 2025
Cash from operations11,86114,575
Purchase of property, plant and equipment1,9242,810
Free cash flow9,93711,765
Dividends paid4,6294,971
Filing20-F20-F

USD million. Free cash flow is cash from operations less the purchase of property, plant and equipment, arithmetic on the two filed lines.

Balance sheet at year end

Year toDec 2024Dec 2025
Total assets104,035114,074
Equity attributable to shareholders40,78648,667
Cash and cash equivalents5,4885,711
Borrowings, as filed30,29529,622
Lease liabilities1,4521,803
Trade and other receivables12,97215,177
Inventories5,2886,557
Goodwill21,02521,242
Filing20-F20-F

USD million, at each fiscal year end.

Ratios on the filed lines

Year toDec 2024Dec 2025
Gross margin81.1%81.9%
Operating margin18.5%23.4%
Net margin13.0%17.4%
Free cash flow margin18.4%20.0%
Return on year-end equity17.2%21.0%
Effective tax rate19.0%17.5%
Filing20-F20-F

Arithmetic on the filed lines of the same year.

Every annual report here

Source

20-F for the year to 31 December 2025, filed 24 February 2026, accession 0001104659-26-019130: the filing on EDGAR. All of AstraZeneca PLC's filings: EDGAR company page. The figures are in US dollars as filed.

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