Open the filing on EDGARTable of ContentsSeptember 30, 2025 Third Quarter Ended September 30, 2025 Financial and Operating Results (continued) September 30, 2025 Third Quarter Ended September 30, 2025 Financial and Operating Results (continued) September 30, 2025 2025 GuidanceSeptember 30, 2025(Dollars in millions, except per share amounts) 2025 Guidance (continued)September 30, 2025(Dollars in millions) 2026 ConsiderationsSeptember 30, 2025 Dispositions and Exchange of Partial InterestsSeptember 30, 2025(Dollars in thousands) Earnings Call Information and About the CompanySeptember 30, 2025 Consolidated Statements of OperationsSeptember 30, 2025(Dollars in thousands, except per share amounts) Consolidated Balance SheetsSeptember 30, 2025(In thousands) Funds From Operations and Funds From Operations per ShareSeptember 30, 2025(In thousands) Funds From Operations and Funds From Operations per Share (continued)September 30, 2025(In thousands, except per share amounts) Company ProfileSeptember 30, 2025 Investor InformationSeptember 30, 2025 Financial and Asset Base HighlightsSeptember 30, 2025(Dollars in thousands, except per share amounts) Financial and Asset Base Highlights (continued)September 30, 2025(Dollars in thousands, except annual rental revenue per occupied RSF amounts) High-Quality and Diverse Client BaseSeptember 30, 2025 Key Operating MetricsSeptember 30, 2025 Same Property PerformanceSeptember 30, 2025 Same Property Performance (Continued)September 30, 2025(Dollars in thousands) Leasing ActivitySeptember 30, 2025(Dollars per RSF) Contractual Lease ExpirationsSeptember 30, 2025 Top 20 TenantsSeptember 30, 2025(Dollars in thousands, except average market cap amounts) Summary of Properties and OccupancySeptember 30, 2025(Dollars in thousands, except per RSF amounts) Property ListingSeptember 30, 2025(Dollars in thousands) Property Listing (continued)September 30, 2025(Dollars in thousands) Property Listing (continued)September 30, 2025(Dollars in thousands) Property Listing (continued)September 30, 2025(Dollars in thousands) Property Listing (continued)September 30, 2025(Dollars in thousands) Property Listing (continued)September 30, 2025(Dollars in thousands) Investments in Real EstateSeptember 30, 2025 Investments in Real EstateSeptember 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Recent DeliveriesSeptember 30, 2025 New Class A/A+ Development and Redevelopment Properties: Recent DeliveriesSeptember 30, 2025(Dollars in thousands) Key New Class A/A+ Development and Redevelopment Properties: 2025 and 2026 Stabilization (Near-Term Deliveries)September 30, 2025 Key New Class A/A+ Development and Redevelopment Properties: 2027 and Beyond Stabilization (Intermediate-Term Deliveries)September 30, 2025 New Class A/A+ Development and Redevelopment Properties: Current ProjectsSeptember 30, 2025 New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)September 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of PipelineSeptember 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)September 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)September 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)September 30, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)September 30, 2025(Dollars in thousands) Construction SpendingSeptember 30, 2025(Dollars in thousands) Capitalization of InterestSeptember 30, 2025(Dollars in thousands) Capitalization of Interest (continued)September 30, 2025 Capitalization of Interest (continued)September 30, 2025 Capitalization of Interest (continued)September 30, 2025 Capitalization of Interest (continued)September 30, 2025 Joint Venture Financial InformationSeptember 30, 2025 Joint Venture Financial Information (continued)September 30, 2025(In thousands) InvestmentsSeptember 30, 2025(Dollars in thousands) Balance SheetSeptember 30, 2025 Key Credit MetricsSeptember 30, 2025 Summary of DebtSeptember 30, 2025(Dollars in millions) Summary of Debt (continued)September 30, 2025 Summary of Debt (continued)September 30, 2025(Dollars in thousands) Summary of Debt (continued)September 30, 2025(Dollars in thousands) Summary of Debt (continued)September 30, 2025(Dollars in thousands) Definitions and ReconciliationsSeptember 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025 Definitions and Reconciliations (continued)September 30, 2025
ALEXANDRIA’S LONG-STANDING TRACK RECORD OF MONETIZING EMBEDDED ASSET VALUE: 2019 - YTD 3Q25 DISPOSITIONS AND PARTIAL INTEREST SALES NASDAQ BIOTECHNOLOGY INDEX (NBI) TSR CONTINUES TO BROADLY TRACK THE DIRECTIONAL PATH OF THE S&P 500 INDEX TSR 2025 RECYCLED ASSETS SOLD OR TO BE SOLD TO FUND OUR CAPITAL NEEDS AND ENABLE ACHIEVEMENT OF 80% ANNUAL RENTAL REVENUE FROM MEGACAMPUSES
ALEXANDRIA’S DISCIPLINED COST-CONTROL AND EFFICIENCY INITIATIVES HAVE DRIVEN SUBSTANTIAL REDUCTIONS IN GENERAL AND ADMINISTRATIVE EXPENSESAlexandria’s 2025 overhead is approximately half that of other S&P 500 REITs
AFTER A SLOW START TO THE YEAR, NOVEL FDA APPROVALS HAVERESUMED A HEALTHY PACE THROUGH THE THIRD QUARTER ALEXANDRIA’S LIFE SCIENCE INDUSTRY ANDCORPORATE RESPONSIBILITY LEADERSHIP ALEXANDRIA’S MEGACAMPUS™ PLATFORM DRIVES SUPERIOR OPERATING RESULTS BY CLUSTERING HIGH-QUALITY COLLABORATIVE LIFE SCIENCE AND ADVANCED TECHNOLOGIES FACILITIES IN TOP INNOVATION MARKETS ALEXANDRIA EXECUTES LARGEST LIFE SCIENCE LEASE IN COMPANY HISTORY WITH A LONG-STANDING MULTINATIONAL PHARMACEUTICAL TENANT FOR A 466,598 RSF BUILD-TO-SUIT RESEARCH HUB AT THE CAMPUS POINT MEGACAMPUS™ IN SAN DIEGO
Guidance for 2025 has been updated to reflect our current view of existing market conditions and assumptions for the year ending December 31, 2025. There can be no assurance that actual amounts will Key Future Megacampus™ Development Project Key Active, Committed Near-Term, and Future Megacampus™ Development Projects Our Megacampus™ Properties Account for 77% of Our Annual Rental Revenue Three Months Ended (unless stated otherwise)9/30/256/30/253/31/2512/31/249/30/24Selected financial data from consolidated financial statements and related informationRental revenues$541,070(1)$553,377$552,112$566,535$579,569Tenant recoveries$194,779$183,902$191,063$196,714$196,175General and administrative expenses$29,224$29,128$30,675$32,730$43,945General and administrative expenses as a percentage of net operating income - trailing 12 months5.7%6.3%6.9%7.6%8.9%Operating margin68%71%70%70%71%Adjusted EBITDA margin71%71%71%72%70%Adjusted EBITDA - quarter annualized$2,130,008$2,174,160$2,165,632$2,273,480$2,219,632Adjusted EBITDA - trailing 12 months$2,185,820$2,208,226$2,218,722$2,228,921$2,184,298Net debt at end of period $13,085,745$12,844,726$12,687,856$11,762,176$12,191,574Net debt and preferred stock to Adjusted EBITDA - quarter annualized6.1x5.9x5.9x5.2x5.5xNet debt and preferred stock to Adjusted EBITDA - trailing 12 months6.0x5.8x5.7x5.3x5.6xTotal debt and preferred stock at end of period$13,593,541$13,294,100$13,090,834$12,244,374$12,691,601Gross assets at end of period$43,791,893$43,770,007$43,486,989$43,152,628$44,112,770Total debt and preferred stock to gross assets at end of period31%30%30%28%29%Fixed-charge coverage ratio - quarter annualized3.9x4.1x4.3x4.3x4.4xFixed-charge coverage ratio - trailing 12 months4.1x4.3x4.4x4.5x4.5xUnencumbered net operating income as a percentage of total net operating income100.0%99.7%99.8%99.9%99.1%Closing stock price at end of period$83.34$72.63$92.51$97.55$118.75Common shares outstanding (in thousands) at end of period 170,339170,146170,130172,203172,244Total equity capitalization at end of period$14,196,059$12,357,709$15,738,715$16,798,446$20,454,023Total market capitalization at end of period$27,789,600$25,651,809$28,829,549$29,042,820$33,145,624Dividend per share - quarter/annualized$1.32/$5.28$1.32/$5.28$1.32/$5.28$1.32/$5.28$1.30/$5.20Dividend payout ratio for the quarter60%57%57%55%55%Dividend yield - annualized6.3%7.3%5.7%5.4%4.4%Amounts related to operating leases:Operating lease liabilities at end of period$361,986$363,419$371,412$507,127$648,338Rent expense$10,645$12,139$11,666$10,685$10,180Capitalized interest$86,091(2)$82,423$80,065$81,586$86,496Average real estate basis capitalized during the period$8,407,332$8,107,180$8,026,566$8,118,010$8,281,318Weighted-average interest rate for capitalization of interest during the period4.10%4.07%3.99%4.02%3.98%Refer to “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Includes a $4.4 million adjustment during 3Q25 to place one tenant located in the Seattle market on cash basis for which collection of future lease payments was no longer probable. (2)Increase in capitalized interest primarily attributable to three repositioning capital projects, which commenced or had increased construction during 3Q25, in our Greater Boston and Texas markets. Three Months Ended (unless stated otherwise)9/30/256/30/253/31/2512/31/249/30/24Amounts included in funds from operations and non-revenue-enhancing capital expendituresStraight-line rent revenue$18,821$18,536$22,023$17,653$29,087Amortization of acquired below-market leases$6,456$10,196$15,222$15,512$17,312Amortization of deferred revenue related to tenant-funded and -built landlord improvements$5,455$2,401$1,651$1,214$329Straight-line rent expense on ground leases$114$87$149$1,021$789Cash payment for ground lease extension$ - $ - $(135,000)$(135,000)$ - Stock compensation expense$10,293$12,530$10,064$12,477$15,525Amortization of loan fees $4,505$4,615$4,691$4,620$4,222Amortization of debt discounts$325$335$349$333$330Non-revenue-enhancing capital expenditures:Building improvements $3,948$4,622$3,789$4,313$4,270Tenant improvements and leasing commissions$16,707$23,971$73,483$81,918$55,920Funds from operations attributable to noncontrolling interests$80,236$80,860$81,012$76,111$78,113Operating statistics and related information (at end of period)Number of properties - North America375384386391406RSF - North America (including development and redevelopment projects under construction)42,887,96443,699,92243,687,34344,124,00146,748,734Total square footage - North America66,417,02667,220,33768,518,18469,289,41173,611,815Annual rental revenue per occupied RSF - North America$58.94$58.68$58.38$56.98$57.09Occupancy of operating properties - North America90.6%(1)90.8%91.7%94.6%94.7%Occupancy of operating and redevelopment properties - North America85.8%86.2%86.9%89.7%89.7%Weighted-average remaining lease term (in years) 7.57.47.67.57.5Total leasing activity - RSF1,171,344769,8151,030,5531,310,9991,486,097Lease renewals and re-leasing of space - change in average new rental rates over expiring rates:Rental rate changes15.2%5.5%18.5%18.1%5.1%Rental rate changes (cash basis)6.1%6.1%7.5%3.3%1.5%RSF (included in total leasing activity above)354,367483,409884,4081,024,8621,278,857Top 20 tenants:Annual rental revenue$768,528$795,244$754,354$741,965$796,898Annual rental revenue from investment-grade or publicly traded large cap tenants90%89%87%92%92%Weighted-average remaining lease term (in years) 9.49.49.69.39.5Same property performance - percentage change over comparable quarter from prior year:Net operating income changes(6.0)%(2)(5.4)%(3.1)%0.6%1.5%Net operating income changes (cash basis)(3.1)%(2)2.0%5.1%6.3%6.5% September 30, 2025September 30, 2025Same Property Financial DataThree Months EndedNine Months EndedSame Property Statistical DataThree Months EndedNine Months EndedPercentage change over comparable period from prior year:Number of same properties316314Net operating income changes(1)(6.0)%(3.1)%Rentable square feet31,953,03231,739,397Net operating income changes (cash basis)(1)(3.1)%3.0%(2)Occupancy - current-period average91.4%92.6%Operating margin67%68%Occupancy - same-period prior-year average94.8%94.6% YearRSFPercentage ofOccupied RSFAnnual Rental Revenue (per RSF)(1)Percentage of Annual Rental Revenue2025(2)434,3711.3%$50.711.1%20263,084,6519.1%$54.438.5%20273,177,0259.4%$55.068.9%20283,954,06311.7%$50.6310.1%20292,115,0706.3%$47.025.0%20302,999,4538.9%$43.326.6%20313,654,09910.8%$55.3610.2%2032968,8482.9%$58.142.9%20332,382,9217.1%$49.055.9%20343,031,4609.0%$67.1610.3%Thereafter7,915,52023.5%$76.0630.5% Summary of properties Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSan Francisco Bay AreaMission BayMegacampus: Alexandria Center® for Science and Technology - Mission Bay(1)1,557,403212,796(3) - 1,770,1998$63,19195.6%95.6%1455(2), 1515(2), 1655, and 1725 Third Street, 1450, 1500, and 1700 Owens Street, and 455 Mission Bay Boulevard SouthMission Bay1,557,403212,796 - 1,770,199863,19195.695.6South San FranciscoMegacampus: Alexandria Technology Center® - Gateway(1)1,431,486 - 237,6841,669,1701276,37780.769.2600(2), 601, 611, 630(2), 650(2), 651, 681, 685, 701, 751, 901(2), and 951(2) Gateway BoulevardMegacampus: Alexandria Center® for Advanced Technologies - South San Francisco812,453 - 107,250919,703551,35195.684.4213(1), 249, 259, 269, and 279 East Grand AvenueAlexandria Center® for Life Science - South San Francisco504,252 - - 504,252328,61983.083.0201 Haskins Way and 400 and 450 East Jamie CourtMegacampus: Alexandria Center® for Advanced Technologies - Tanforan445,232 - - 445,23222,359100.0100.01122 and 1150 El Camino RealAlexandria Center® for Life Science - Millbrae(1)285,346 - - 285,346135,828100.0100.0230 Harriet Tubman Way500 Forbes Boulevard(1)155,685 - - 155,685110,908100.0100.0South San Francisco3,634,454 - 344,9343,979,38824205,44289.181.3Greater StanfordMegacampus: Alexandria Center® for Life Science - San Carlos738,038 - - 738,038943,98386.586.5825, 835, 960, and 1501-1599 Industrial RoadAlexandria Stanford Life Science District705,442 - - 705,442954,52086.486.43160, 3165, 3170, and 3181 Porter Drive and 3301, 3303, 3305, 3307, and 3330 Hillview Avenue3412, 3420, 3440, 3450, and 3460 Hillview Avenue340,103 - - 340,103524,59386.586.53875 Fabian Way228,000 - - 228,00019,642100.0100.02475 and 2625/2627/2631 Hanover Street and 1450 Page Mill Road198,548 - - 198,548313,774100.0100.02100 and 2200 Geng Road62,526 - - 62,52622,732100.0100.03350 West Bayshore Road61,431 - - 61,43113,64173.273.2Greater Stanford2,334,088 - - 2,334,08830152,88588.988.9San Francisco Bay Area7,525,945212,796344,9348,083,67562$421,51890.4%86.4%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.(2)We own 100% of this property. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSan DiegoTorrey PinesMegacampus: One Alexandria Square1,090,828 - - 1,090,82810$77,20890.9%90.9%3115 and 3215(1) Merryfield Row, 3010, 3013, and 3033 Science Park Road, 10935, 10945, 10955, and 10970 Alexandria Way, 10996 Torreyana Road, and 3545 Cray CourtARE Torrey Ridge299,138 - - 299,138313,26379.779.710578, 10618, and 10628 Science Center DriveARE Nautilus218,640 - - 218,640415,108100.0100.03530 and 3550 John Hopkins Court and 3535 and 3565 General Atomics CourtTorrey Pines1,608,606 - - 1,608,60617105,57990.190.1University Town CenterMegacampus: Campus Point by Alexandria(1)1,310,696426,927 - 1,737,623884,05899.599.59880(2), 10210, 10290, and 10300 Campus Point Drive and 4135, 4155, 4224, and 4242 Campus Point CourtMegacampus: 5200 Illumina Way(1)792,687 - - 792,687629,978100.0100.09625 Towne Centre Drive(1)163,648 - - 163,64816,520100.0100.0University Town Center2,267,031426,927 - 2,693,95815120,55699.799.7Sorrento MesaMegacampus: SD Tech by Alexandria(1)829,437221,589 - 1,051,0261137,84196.196.19605, 9645, 9675, 9725, 9735, 9808, 9855, and 9868 Scranton Road, and 10055, 10065, and 10075 Barnes Canyon RoadMegacampus: Sequence District by Alexandria671,039 - - 671,039623,458100.0100.06290, 6310, 6340, 6350, 6420, and 6450 Sequence DriveSummers Ridge Science Park(1)316,531 - - 316,531411,521100.0100.09965, 9975, 9985, and 9995 Summers Ridge RoadScripps Science Park by Alexandria144,113 - - 144,113111,379100.0100.010102 Hoyt Park DriveARE Portola101,857 - - 101,85734,207100.0100.06175, 6225, and 6275 Nancy Ridge Drive5810/5820 Nancy Ridge Drive83,354 - - 83,35414,621100.0100.09877 Waples Street63,774 - - 63,77412,680100.0100.05871 Oberlin Drive33,842 - - 33,84212,103100.0100.0Sorrento Mesa2,243,947221,589 - 2,465,5362897,81098.698.6Sorrento Valley3911, 3931, 3985, 4025, 4031, and 4045 Sorrento Valley Boulevard151,406 - - 151,40662,50232.732.711045 and 11055 Roselle Street43,313 - - 43,31322,19196.196.1Sorrento Valley194,719 - - 194,71984,69346.846.8San Diego6,314,303648,516 - 6,962,81968$328,63895.2%95.2%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.(2)We own 100% of this property. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSeattleLake UnionMegacampus: Alexandria Center® for Life Science - Eastlake1,151,672 - - 1,151,6729$69,33391.6%91.6%1150, 1201(1), 1208(1), 1551, 1600, and 1616 Eastlake Avenue East, 188 and 199 East Blaine Street, and 1600 Fairview Avenue EastMegacampus: Alexandria Center® for Advanced Technologies - South Lake Union413,178227,577 - 640,755423,43698.898.8400(1) and 701 Dexter Avenue North, 428 Westlake Avenue North, and 219 Terry Avenue NorthLake Union1,564,850227,577 - 1,792,4271392,76993.593.5Elliott Bay410 West Harrison Street and 410 Elliott Avenue West20,101 - - 20,1012710100.0100.0BothellMegacampus: Alexandria Center® for Advanced Technologies - Canyon Park1,065,132 - - 1,065,1322221,27787.187.122121 and 22125 17th Avenue Southeast, 22021, 22025, 22026, 22030, 22118, and 22122 20th Avenue Southeast, 22333, 22422, 22515, 22522, 22722, and 22745 29th Drive Southeast, 21540, 22213 and 22309 30th Drive Southeast, and 1629, 1631, 1725, 1916, and 1930 220th Street SoutheastAlexandria Center® for Advanced Technologies - Monte Villa Parkway464,889 - - 464,889611,41283.983.93301, 3303, 3305, 3307, 3555, and 3755 Monte Villa ParkwayBothell1,530,021 - - 1,530,0212832,68986.186.1Other63,057 - - 63,0572666100.0100.0Seattle3,178,029227,577 - 3,405,60645126,83490.190.1MarylandRockvilleMegacampus: Alexandria Center® for Life Science - Shady Grove1,691,960 - - 1,691,9602093,26894.694.69601, 9603, 9605, 9704, 9708, 9712, 9714, 9800, 9804, 9808, 9900, and 9950 Medical Center Drive, 14920 and 15010 Broschart Road, 9920 Belward Campus Drive, and 9810 and 9820 Darnestown Road1330 Piccard Drive131,507 - - 131,50714,324100.0100.01405 and 1450(1) Research Boulevard114,182 - - 114,18222,95872.872.81500 and 1550 East Gude Drive91,359 - - 91,35921,844100.0100.05 Research Place63,852 - - 63,85213,108100.0100.05 Research Court51,520 - - 51,52011,976100.0100.012301 Parklawn Drive49,185 - - 49,18511,598100.0100.0Rockville2,193,565 - - 2,193,56528$109,07694.4%94.4%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalMaryland (continued)GaithersburgAlexandria Technology Center® - Gaithersburg I619,061 - - 619,0619$19,64293.6%93.6%9, 25, 35, 45, 50, and 55 West Watkins Mill Road and 910, 930, and 940 Clopper RoadAlexandria Technology Center® - Gaithersburg II486,300 - - 486,300717,64095.195.1700, 704, and 708 Quince Orchard Road and 19, 20, 21, and 22 Firstfield Road20400 Century Boulevard81,006 - - 81,00611,858100.0100.0401 Professional Drive63,207 - - 63,20711,43482.782.7950 Wind River Lane50,000 - - 50,00011,234100.0100.0620 Professional Drive27,950 - - 27,95011,207100.0100.0Gaithersburg1,327,524 - - 1,327,5242043,01594.494.4Beltsville8000/9000/10000 Virginia Manor Road 191,884 - - 191,88413,396100.0100.0101 West Dickman Street(1)142,933 - - 142,93311,72671.371.3Beltsville334,817 - - 334,81725,12287.887.8Maryland3,855,906 - - 3,855,90650157,21393.993.9Research TriangleResearch TriangleMegacampus: Alexandria Center® for Life Science - Durham2,214,887 - - 2,214,8871644,55097.697.66, 8, 10, 12, 14, 40, 41, 42, and 65 Moore Drive, 21, 25, 27, 29, and 31Alexandria Way, 2400 Ellis Road, and 14 TW Alexander DriveMegacampus: Alexandria Center® for Advanced Technologies and AgTech - Research Triangle711,693 - - 711,693628,72692.992.96, 8, 10, and 12 Davis Drive and 5 and 9 Laboratory DriveMegacampus: Alexandria Center® for Sustainable Technologies259,962 - - 259,96267,25984.884.8104, 108, 110, 112, and 114 TW Alexander Drive and 5 Triangle DriveAlexandria Technology Center® - Alston160,574 - - 160,57432,79878.278.2100, 800, and 801 Capitola DriveAlexandria Innovation Center® - Research Triangle136,635 - - 136,63534,01995.395.37010, 7020, and 7030 Kit Creek Road2525 East NC Highway 5482,996 - - 82,99613,580100.0100.0407 Davis Drive81,956 - - 81,95613,323100.0100.0Research Triangle3,648,703 - - 3,648,70336$94,25594.9%94.9%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalNew York CityNew York CityMegacampus: Alexandria Center® for Life Science - New York City742,700 - - 742,7003$69,31798.3%98.3%430 and 450 East 29th StreetNew York City742,700 - - 742,700369,31798.398.3TexasAustinMegacampus: Intersection Campus1,525,359 - - 1,525,3591233,69483.083.0507 East Howard Lane, 13011 McCallen Pass, 13813 and 13929 Center Lake Drive, and 12535, 12545, 12555, and 12565 Riata Vista CircleAustin1,525,359 - - 1,525,3591233,69483.083.0Greater HoustonAlexandria Center® for Advanced Technologies at The Woodlands 120,828 - 73,298194,12613,17241.525.88800 Technology Forest PlaceTexas1,646,187 - 73,2981,719,4851336,86679.976.5Canada979,575 - 56,3141,035,8891120,18690.385.4Non-cluster/other markets315,440 - - 315,440912,19569.669.6North America, excluding properties held for sale37,303,0131,672,2962,100,86841,076,1773611,975,48690.6%85.8%Properties held for sale 1,811,787 - - 1,811,7871453,26665.9%65.9%Total - North America39,114,8001,672,2962,100,86842,887,964375$2,028,752 99 Coolidge Avenue4135 Campus Point CourtGreater Boston/Cambridge/Inner SuburbsSan Diego/University Town Center191,396 RSF426,927 RSF81% Leased/Negotiating 100% Leased Property/Market/SubmarketSquare FootagePercentageOccupancy(1)Dev/RedevIn ServiceCIPTotalLeasedLeased/NegotiatingInitialStabilizedUnder construction2025 and 2026 stabilization99 Coolidge Avenue/Greater Boston/Cambridge/Inner SuburbsDev129,413191,396320,80981%81%4Q234Q264135 Campus Point Court/San Diego/University Town CenterDev - 426,927426,9271001003Q263Q2610075 Barnes Canyon Road/San Diego/Sorrento MesaDev31,490221,589253,07968681Q252H268800 Technology Forest Place/Texas/Greater HoustonRedev50,09473,298123,39241412Q234Q26CanadaRedev194,47656,314250,79078783Q234Q25405,473969,5241,374,99780802027 and beyond stabilizationOne Hampshire Street/Greater Boston/CambridgeRedev - 104,956104,956 - - 20272028311 Arsenal Street/Greater Boston/Cambridge/Inner SuburbsRedev56,904333,758390,6627720272027421 Park Drive/Greater Boston/FenwayDev - 392,011392,011131320272028401 Park Drive/Greater Boston/FenwayRedev - 137,675137,675 - - 2027202740, 50, and 60 Sylvan Road/Greater Boston/Route 128Redev - 596,064596,06433334Q262027Other/Greater BostonRedev - 453,869453,869 - - 202720271450 Owens Street/San Francisco Bay Area/Mission BayDev - 212,796212,796 - 4920272027651 Gateway Boulevard/San Francisco Bay Area/South San Francisco(2)Redev89,022237,684326,70621211Q242027269 East Grand Avenue/San Francisco Bay Area/South San FranciscoRedev - 107,250107,250 - - 2H262027701 Dexter Avenue North/Seattle/Lake UnionDev - 227,577227,57723234Q262027145,9262,803,6402,949,566100% Pre-leased committed near-term project expected to commence construction in the next yearCampus Point by Alexandria/San Diego/University Town Center(3)Dev - 466,598466,59810010020282028Total 2027 and beyond stabilization and committed near-term project145,9263,270,2383,416,1642528551,3994,239,7624,791,16141%43%(1)Initial occupancy dates are subject to leasing and/or market conditions. Stabilized occupancy may vary depending on single tenancy versus multi-tenancy. Multi-tenant projects may increase in occupancy over time. (2)We continue to build out this project on a floor-by-floor basis. As of September 30, 2025, the remaining cost to complete is $138 million, or 28% of the total cost at completion. (3)Represents a single-tenant project that expands the existing Campus Point by Alexandria Megacampus, where we currently have a 55% interest. The project is fully leased to a longtime multinational pharmaceutical tenant that currently occupies two buildings within the Megacampus: one building aggregating 52,620 RSF and another building aggregating 52,853 RSF. These buildings generated annual rental revenue of $7.5 million as of 3Q25. At the beginning of 2026, the tenant will vacate the 52,620 RSF building, and during 2028, the tenant will vacate the 52,853 RSF building. We expect to fund the majority of future construction costs at the Megacampus until our ownership interest increases from 55% to 75%, after which future capital would be contributed pro rata with our joint venture partner. Our Ownership InterestAt 100%Unlevered YieldsProperty/Market/SubmarketIn ServiceCIPCost to CompleteTotal atCompletionInitial StabilizedInitial Stabilized (Cash Basis)Under construction2025 and 2026 stabilization with 80% leased/negotiating99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs100%$154,608$210,017$79,375$444,0006.0%6.8%4135 Campus Point Court/San Diego/University Town Center55.0% - 412,619111,381524,0009.0%6.2%10075 Barnes Canyon Road/San Diego/Sorrento Mesa50.0%25,573217,84177,586321,0005.5%5.7%8800 Technology Forest Place/Texas/Greater Houston100%60,48046,5264,994112,0006.3%6.0%Canada100%95,75014,6714,579115,0006.0%6.0%336,411901,6742027 and beyond stabilization(1)One Hampshire Street/Greater Boston/Cambridge100% - 173,897TBD311 Arsenal Street/Greater Boston/Cambridge/Inner Suburbs100%21,756298,829421 Park Drive/Greater Boston/Fenway100% - 561,633401 Park Drive/Greater Boston/Fenway100% - 174,40240, 50, and 60 Sylvan Road/Greater Boston/Route 128100% - 511,925Other/Greater Boston100% - 160,9501450 Owens Street/San Francisco Bay Area/Mission Bay25.0% - 245,677651 Gateway Boulevard/San Francisco Bay Area/South San Francisco50.0%116,744232,429137,827487,0005.0%5.1%269 East Grand Avenue/San Francisco Bay Area/South San Francisco100% - 109,065TBD701 Dexter Avenue North/Seattle/Lake Union100% - 293,922138,5002,762,729474,9113,664,403100% Pre-leased committed near-term project expected to commence construction in the next yearCampus Point by Alexandria/San Diego/University Town Center(2)55.0% - 60,398599,602660,0007.3%6.5%Total$474,911$3,724,801$2,670,000(3)$6,870,000(3)Our share of investment(3)(4)$410,000$3,100,000$2,180,000$5,690,000Refer to “Initial stabilized yield (unlevered)” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We expect to provide total estimated costs and related yields for each project with estimated stabilization in 2027 and beyond over the next several quarters.(2)Refer to footnote 3 on the prior page for additional details.(3)Represents dollar amount rounded to the nearest $10 million and includes preliminary estimated amounts for projects listed as TBD.(4)Represents our share of investment based on our ownership percentage upon completion of development or redevelopment projects. 76% of Our Total Development and Redevelopment Pipeline RSF MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionCommitted Near TermFutureTotal(1)San Francisco Bay AreaMegacampus: Alexandria Center® for Science and Technology - Mission Bay/Mission Bay25.0%$245,677212,796 - - 212,7961450 Owens StreetMegacampus: Alexandria Technology Center® - Gateway/South San Francisco50.0%259,005237,684 - 291,000528,684651 Gateway BoulevardMegacampus: Alexandria Center® for Advanced Technologies - South San Francisco/South San Francisco100%115,720107,250 - 90,000197,250211(2) and 269 East Grand AvenueMegacampus: Alexandria Center® for Advanced Technologies - Tanforan/South San Francisco100%429,101 - - 1,930,0001,930,0001122, 1150, and 1178 El Camino RealAlexandria Center® for Life Science - Millbrae/South San Francisco48.5%158,718 - - 348,401348,401201 and 231 Adrian Road and 30 Rollins RoadMegacampus: Alexandria Center® for Life Science - San Carlos/Greater Stanford100%479,347 - - 1,497,8301,497,830960 Industrial Road, 987 and 1075 Commercial Street, and 888 Bransten Road3825 and 3875 Fabian Way/Greater Stanford100%164,226 - - 478,000478,0002100, 2200, 2300, and 2400 Geng Road/Greater Stanford100%81,552 - - 240,000240,000Megacampus: 88 Bluxome Street/SoMa100%418,909 - - 1,070,9251,070,925$2,352,255557,730 - 5,946,1566,503,886Refer to “Megacampus” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.(2)Includes a property in which we own a partial interest through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionCommitted Near TermFutureTotal(1)San DiegoMegacampus: Campus Point by Alexandria/University Town Center55.0%(3)$620,470426,927466,598500,8591,394,38410010(2), 10140(2), 10210, and 10260 Campus Point Drive and 4135, 4161, 4165, and 4224 Campus Point CourtMegacampus: SD Tech by Alexandria/Sorrento Mesa50.0%414,636221,589 - 493,845715,4349805 Scranton Road and 10075 Barnes Canyon Road11255 and 11355 North Torrey Pines Road/Torrey Pines100%158,326 - - 215,000215,000Megacampus: One Alexandria Square/Torrey Pines100%64,545 - - 125,280125,28010975 and 10995 Torreyana RoadMegacampus: 5200 Illumina Way/University Town Center51.0%17,536 - - 451,832451,8329625 Towne Centre Drive/University Town Center30.0%837 - - 100,000100,000Megacampus: Sequence District by Alexandria/Sorrento Mesa100%48,303 - - 1,661,9151,661,9156290, 6310, 6340, 6350, and 6450 Sequence Drive4075 Sorrento Valley Boulevard/Sorrento Valley100%28,167 - - 144,000144,000Other development and redevelopment projects(4)78,036 - - 475,000475,0001,430,856648,516466,5984,167,7315,282,845SeattleMegacampus: Alexandria Center® for Advanced Technologies - South Lake Union/Lake Union(5)584,896227,577 - 1,057,4001,284,977601 and 701 Dexter Avenue North and 800 Mercer Street1010 4th Avenue South/SoDo100%62,116 - - 544,825544,825410 West Harrison Street/Elliott Bay100% - - - 91,00091,000Megacampus: Alexandria Center® for Advanced Technologies - Canyon Park/Bothell100%19,739 - - 230,000230,00021660 20th Avenue SoutheastOther development and redevelopment projects100%151,672 - - 706,087706,087$818,423227,577 - 2,629,3122,856,889Refer to “Megacampus” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.(2)We have a 100% interest in this property.(3)The noncontrolling interest share of our joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases from 55% to 75%, after which future capital would be contributed pro rata with our partner.(4)Includes a property in which we own a partial interest through a real estate joint venture. (5)We have a 100% interest in 601 and 701 Dexter Avenue North aggregating 415,977 RSF and a 60% interest in the future development project at 800 Mercer Street aggregating 869,000 RSF. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionCommitted Near TermFutureTotal(1)MarylandMegacampus: Alexandria Center® for Life Science - Shady Grove/Rockville100%$25,629 - - 296,000296,0009830 Darnestown Road25,629 - - 296,000296,000Research TriangleMegacampus: Alexandria Center® for Life Science - Durham/Research Triangle100%163,894 - - 2,060,0002,060,000Megacampus: Alexandria Center® for Advanced Technologies and AgTech - Research Triangle/Research Triangle100%111,537 - - 1,170,0001,170,0004 and 12 Davis DriveMegacampus: Alexandria Center® for NextGen Medicines/Research Triangle100%113,456 - - 1,055,0001,055,0003029 East Cornwallis RoadMegacampus: Alexandria Center® for Sustainable Technologies/Research Triangle100%55,732 - - 750,000750,000120 TW Alexander Drive, 2752 East NC Highway 54, and 10 South Triangle Drive100 Capitola Drive/Research Triangle100% - - - 65,96565,965Other development and redevelopment projects100%4,185 - - 76,26276,262448,804 - - 5,177,2275,177,227New York CityMegacampus: Alexandria Center® for Life Science - New York City/New York City100%175,666 - - 550,000(2)550,000$175,666 - - 550,000550,000Refer to “Megacampus” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.(2)During the three months ended September 30, 2024, we filed a lawsuit against the New York City Health + Hospitals Corporation and the New York City Economic Development Corporation for fraud and breach of contract concerning our option to ground lease a land parcel to develop a future world-class life science building within the Alexandria Center® for Life Science - New York City Megacampus. Refer to our quarterly report on Form 10-Q for the three months ended September 30, 2025 filed with the Securities and Exchange Commission on October 27, 2025 for additional details. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionCommitted Near TermFutureTotal(1)TexasAlexandria Center® for Advanced Technologies at The Woodlands/Greater Houston100%$49,57573,298 - 116,405189,7038800 Technology Forest Place1001 Trinity Street and 1020 Red River Street/Austin100%133,684 - - 250,010250,010Other development and redevelopment projects100%59,432 - - 344,000344,000242,69173,298 - 710,415783,713Canada100%14,67156,314 - 371,743428,057Other development and redevelopment projects100%47,504 - - 350,000350,000Total pipeline as of September 30, 2025, excluding properties held for sale8,596,2643,773,164466,59824,257,78228,497,544Properties held for sale112,681 - - 939,756939,756Total pipeline as of September 30, 2025$8,708,945(2)3,773,164466,59825,197,53829,437,300 Construction spendingNine Months Ended September 30, 2025Projected Guidance Midpoint for Year Ending December 31, 2025Year Ended December 31, 2024Construction of Class A/A+ properties:Active construction projectsUnder construction$799,723$1,240,000$1,791,097Future pipeline pre-constructionPrimarily Megacampus expansion pre-construction work (entitlement, design, and site work)365,654500,000426,948Revenue- and non-revenue-enhancing capital expenditures230,867415,000(1)273,377Construction spending (before contributions from noncontrolling interests or tenants):1,396,2442,155,0002,491,422Contributions from noncontrolling interests (consolidated real estate joint ventures)(156,668)(230,000)(2)(343,798)Tenant-funded and -built landlord improvements(171,153)(175,000)(129,152)Total construction spending$1,068,423$1,750,000$2,018,4722025 guidance range for construction spending$1,450,000 - $2,050,000 Average Real Estate Basis Capitalized During YTD 3Q25Percentage of Total Average Real Estate Basis CapitalizedLeased/NegotiatingKey Categories of Real Estate Basis CapitalizedConstruction of Class A/A+ properties:Development and redevelopment of projects under construction and one 100% pre-leased committed near-term project expected to commence construction in the next year:2025 and 2026 stabilization80%$650,0048%2027 and beyond stabilization28%2,157,70126Smaller redevelopments and repositioning of capital projects1,128,760(1)14Future pipeline projects with critical pre-construction milestones during 4Q25 and 2026:(3)Megacampus projects3,032,254(2)(3)37Non-Megacampus projects1,211,641(3)15Total average real estate basis capitalized(4)$8,180,360100% DebtStated RateInterest Rate(1)Maturity Date(2)Principal Payments Remaining for the Periods Ending December 31,PrincipalUnamortized (Deferred Financing Cost), (Discount)/PremiumTotal20252026202720282029ThereafterUnsecured senior line of credit and commercial paper program(3)(3)4.52%(3)1/22/30(3)$ - $ - $ - $ - $ - $1,550,000$1,550,000$(1,458)$1,548,542Unsecured senior notes payable4.30%4.501/15/26 - 300,000 - - - - 300,000(160)299,840Unsecured senior notes payable3.80%3.964/15/26 - 350,000 - - - - 350,000(285)349,715Unsecured senior notes payable3.95%4.131/15/27 - - 350,000 - - - 350,000(684)349,316Unsecured senior notes payable3.95%4.071/15/28 - - - 425,000 - - 425,000(994)424,006Unsecured senior notes payable4.50%4.607/30/29 - - - - 300,000 - 300,000(860)299,140Unsecured senior notes payable2.75%2.8712/15/29 - - - - 400,000 - 400,000(1,757)398,243Unsecured senior notes payable4.70%4.817/1/30 - - - - - 450,000450,000(1,779)448,221Unsecured senior notes payable4.90%5.0512/15/30 - - - - - 700,000700,000(4,143)695,857Unsecured senior notes payable3.375%3.488/15/31 - - - - - 750,000750,000(3,866)746,134Unsecured senior notes payable2.00%2.125/18/32 - - - - - 900,000900,000(6,275)893,725Unsecured senior notes payable1.875%1.972/1/33 - - - - - 1,000,0001,000,000(6,458)993,542Unsecured senior notes payable2.95%3.073/15/34 - - - - - 800,000800,000(6,668)793,332Unsecured senior notes payable4.75%4.884/15/35 - - - - - 500,000500,000(4,615)495,385Unsecured senior notes payable5.50%5.6610/1/35 - - - - - 550,000550,000(6,470)543,530Unsecured senior notes payable5.25%5.385/15/36 - - - - - 400,000400,000(3,853)396,147Unsecured senior notes payable4.85%4.934/15/49 - - - - - 300,000300,000(2,785)297,215Unsecured senior notes payable4.00%3.912/1/50 - - - - - 700,000700,0009,880709,880Unsecured senior notes payable3.00%3.085/18/51 - - - - - 850,000850,000(10,938)839,062Unsecured senior notes payable3.55%3.633/15/52 - - - - - 1,000,0001,000,000(13,339)986,661Unsecured senior notes payable5.15%5.264/15/53 - - - - - 500,000500,000(7,427)492,573Unsecured senior notes payable5.625%5.715/15/54 - - - - - 600,000600,000(6,525)593,475Unsecured debt weighted-average interest rate/subtotal3.97 - 650,000350,000425,000700,00011,550,00013,675,000(81,459)13,593,541Weighted-average interest rate/total 3.97%$ - $650,000$350,000$425,000$700,000$11,550,000$13,675,000$(81,459)$13,593,541Balloon payments$ - $650,000$350,000$425,000$700,000$11,550,000$13,675,000$(81,459)$13,593,541Principal amortization - - - - - - - - - Total debt$ - $650,000$350,000$425,000$700,000$11,550,000$13,675,000$(81,459)$13,593,541Fixed-rate debt$ - $650,000$350,000$425,000$700,000$10,000,000$12,125,000$(80,001)$12,044,999Variable-rate debt - - - - - 1,550,0001,550,000(1,458)1,548,542Total debt$ - $650,000$350,000$425,000$700,000$11,550,000$13,675,000$(81,459)$13,593,541Weighted-average stated rate on maturing debtN/A4.03%3.95%3.95%3.50%3.89% Key Active and Future Megacampus™ Development Project Key Future Megacampus™ Development Project ALEXANDRIA: THE MOST TRUSTED BRAND IN LIFE SCIENCE REAL ESTATE™ WE INVENTED IT.WE DOMINATE IT. ALEXANDRIA’SMEGACAMPUS™ PLATFORM REPRESENTS77%OF OUR ANNUAL RENTAL REVENUE COMPANY HIGHLIGHTSPagePageMission and Cluster Model .....................................................................iiiEARNINGS PRESS RELEASEThird Quarter Ended September 30, 2025 Financial and Operating Results ................................................................................1Earnings Call Information and About the Company .......................82025 Guidance .........................................................................................4Consolidated Statements of Operations ..........................................92026 Considerations ...............................................................................6Consolidated Balance Sheets............................................................10Dispositions and Exchange of Partial Interests...................................7Funds From Operations and Funds From Operations per Share 11SUPPLEMENTAL INFORMATIONCompany Profile.......................................................................................14External Growth / Investments in Real EstateInvestor Information .................................................................................15Investments in Real Estate ................................................................32Financial and Asset Base Highlights.....................................................16New Class A/A+ Development and Redevelopment Properties:High-Quality and Diverse Client Base .................................................18Recent Deliveries ...........................................................................34Internal Operating MetricsCurrent Projects..............................................................................36Key Operating Metrics.............................................................................19Summary of Pipeline......................................................................40Same Property Performance..................................................................20Construction Spending........................................................................45Leasing Activity.........................................................................................22Capitalization of Interest .....................................................................46Contractual Lease Expirations ...............................................................23Joint Venture Financial Information...................................................51Top 20 Tenants .........................................................................................24Balance Sheet ManagementSummary of Properties and Occupancy ..............................................25Investments ..........................................................................................53Property Listing ........................................................................................26Balance Sheet ......................................................................................54Key Credit Metrics ...............................................................................55Summary of Debt .................................................................................56Definitions and ReconciliationsDefinitions and Reconciliations..........................................................61 Summary of Key Items That May Impact 2026 Results Interest Sold/AcquiredSquare FootageGain on Sales of Real EstatePropertySubmarket/MarketDate of TransactionOperatingFuture Development PriceDispositionsCompleted in 1H25$260,639$13,165Completed in 3Q25:5505 Morehouse Drive(1)Sorrento Mesa/San Diego 8/26/25100%79,945 - 45,000 - Other Various35,23276Total dispositions completed in 3Q2580,232(2)76(3)Completed in October 2025: 550 Arsenal Street(4)Cambridge/Inner Suburbs/Greater Boston10/15/25100%249,275281,59299,250 - OtherVarious68,1294,362167,379(2)4,362Total dispositions as of October 27, 2025508,250$17,603Our share of pending dispositions subject to non-refundable deposits, signed letters of intent, and/or purchase and sale agreement negotiations1,032,495Completed and pending YTD 2025 dispositions, excluding exchange of partial interests (see below)$1,540,7452025 guidance range for dispositions and sales of partial interests$1,100,000 - $1,900,0002025 guidance midpoint for dispositions and sales of partial interests$1,500,000Exchange of partial interests(5)Disposition of Pacific Technology ParkSorrento Mesa/San Diego9/9/2550%544,352 - $96,000$9,290Acquisition of 199 East Blaine StreetLake Union/Seattle9/9/2570%115,084 - (94,430)Difference in sales price received in cash$1,570 Three Months EndedNine Months Ended 9/30/256/30/253/31/2512/31/249/30/249/30/259/30/24Revenues: Income from rentals$735,849$737,279$743,175$763,249$775,744$2,216,303$2,286,457Other income16,09524,76114,98325,69615,86355,83940,992Total revenues751,944762,040758,158788,945791,6072,272,1422,327,449Expenses:Rental operations239,234224,433226,395240,432233,265690,062668,833General and administrative29,22429,12830,67532,73043,94589,027135,629Interest54,85255,29650,87655,65943,550161,024130,179Depreciation and amortization340,230346,123342,062330,108293,9981,028,415872,272Impairment of real estate323,870(1)129,60632,154186,5645,741485,63036,504Loss on early extinguishment of debt107 - - - - 107 - Total expenses987,517784,586682,162845,493620,4992,454,2651,843,417Equity in earnings (losses) of unconsolidated real estate joint ventures201(9,021)(507)6,635139(9,327)424Investment income (loss)28,161(30,622)(49,992)(67,988)15,242(52,453)14,866Gain on sales of real estate9,366 - 13,165101,80627,11422,53127,506Net (loss) income(197,845)(62,189)38,662(16,095)213,603(221,372)526,828Net income attributable to noncontrolling interests(34,909)(44,813)(47,601)(46,150)(45,656)(127,323)(141,634)Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s stockholders(232,754)(107,002)(8,939)(62,245)167,947(348,695)385,194Net income attributable to unvested restricted stock awards(2,183)(2,609)(2,660)(2,677)(3,273)(7,452)(10,717)Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s common stockholders$(234,937)$(109,611)$(11,599)$(64,922)$164,674$(356,147)$374,477Net (loss) income per share attributable to Alexandria Real Estate Equities, Inc.’s common stockholders:Basic$(1.38)$(0.64)$(0.07)$(0.38)$0.96$(2.09)$2.18Diluted$(1.38)$(0.64)$(0.07)$(0.38)$0.96$(2.09)$2.18Weighted-average shares of common stock outstanding:Basic170,181170,135170,522172,262172,058170,278172,007Diluted170,181170,135170,522172,262172,058170,278172,007Dividends declared per share of common stock$1.32$1.32$1.32$1.32$1.30$3.96$3.87 Same Property Performance:Net Operating Income ChangesRental Rate Growth: Renewed/Re-Leased SpaceMargins(2)Favorable Lease Structure(3)OperatingAdjusted EBITDAStrategic Lease Structure by Owner and Operator of Collaborative Megacampus Ecosystems68%71%Increasing cash flowsPercentage of leases containing annual rent escalations97%Stable cash flowsLong-Duration Lease Terms(4)Percentage of triple net leases91%9.4 Years7.5 YearsLower capex burdenPercentage of leases providing for therecapture of capital expenditures 92%Top 20 TenantsAll Tenants Incremental Annual Net Operating Income Generated From YTD 3Q25 Deliveries Consolidated Real Estate Joint VenturesPropertyMarketSubmarketNoncontrolling Interest Share(1)Operating RSF at 100%50 and 60 Binney StreetGreater BostonCambridge/Inner Suburbs66.0%532,39575/125 Binney StreetGreater BostonCambridge/Inner Suburbs60.0%388,270100 and 225 Binney Street and 300 Third StreetGreater BostonCambridge/Inner Suburbs70.0%870,64115 Necco StreetGreater BostonSeaport Innovation District43.3%345,996285, 299, 307, and 345 Dorchester AvenueGreater BostonSeaport Innovation District40.0% - (2)Alexandria Center® for Science and Technology - Mission Bay(3)San Francisco Bay AreaMission Bay75.0%548,215601, 611, 651(2), 681, 685, and 701 Gateway BoulevardSan Francisco Bay AreaSouth San Francisco50.0%874,234751 Gateway BoulevardSan Francisco Bay AreaSouth San Francisco49.0%230,592211 and 213 East Grand AvenueSan Francisco Bay AreaSouth San Francisco70.0%300,930500 Forbes BoulevardSan Francisco Bay AreaSouth San Francisco90.0%155,685Alexandria Center® for Life Science - MillbraeSan Francisco Bay AreaSouth San Francisco51.5%285,3463215 Merryfield RowSan DiegoTorrey Pines70.0%170,523Campus Point by Alexandria(2)(4)San DiegoUniversity Town Center45.0%(5)1,212,4145200 Illumina WaySan DiegoUniversity Town Center49.0%792,6879625 Towne Centre DriveSan DiegoUniversity Town Center70.0%163,648SD Tech by Alexandria(2)(6)San DiegoSorrento Mesa50.0%829,437Summers Ridge Science Park(7)San DiegoSorrento Mesa70.0%316,5311201 and 1208 Eastlake Avenue EastSeattleLake Union70.0%206,134400 Dexter Avenue NorthSeattleLake Union70.0%290,754800 Mercer StreetSeattleLake Union40.0% - (2)Unconsolidated Real Estate Joint VenturesPropertyMarketSubmarketOur Ownership Share(8)Operating RSF at 100%1655 and 1725 Third StreetSan Francisco Bay AreaMission Bay10.0%586,2081450 Research BoulevardMarylandRockville73.2%(9)42,012101 West Dickman StreetMarylandBeltsville58.4%(9)142,933 We hold investments in publicly traded companies and privately held entities primarily involved in the life science industry. The tables below summarize components of our investment income LiquidityLimited Outstanding Borrowings and Significant Availability on Unsecured Senior Line of Credit(in millions)$4.2B(in millions)Availability under our unsecured senior line of credit, net of amounts outstanding under our commercial paper program$3,450Cash, cash equivalents, and restricted cash584Investments in publicly traded companies124Liquidity as of September 30, 2025$4,158Net Debt and Preferred Stock to Adjusted EBITDA(1)Fixed-Charge Coverage Ratio(1) This section contains additional details for sections throughout the Supplemental Information and the accompanying Earnings Press Release, as well as explanations and reconciliations of certain non- Annual rental revenue Class A/A+ properties and AAA locations Development, redevelopment, and pre-construction (continued) Fixed-charge coverage ratio Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s Initial stabilized yield (unlevered) Investments Investments in real estate Investments in real estate (continued) Joint venture financial information Key items included in net income attributable to Alexandria’s common stockholders Net debt and preferred stock to Adjusted EBITDA Net operating income, net operating income (cash basis), and operating margin Net operating income, net operating income (cash basis), and operating margin (continued) Operating statistics Same property comparisons (continued) Stabilized occupancy date Unencumbered net operating income as a percentage of total net operating income Weighted-average shares of common stock outstanding - diluted ALEXANDRIA CONTINUES TO HAVE A STRONG AND FLEXIBLE BALANCE SHEET WITH SIGNIFICANT LIQUIDITY Alexandria Real Estate Equities, Inc. Reports: Solid leasing volume and rental rate increases Leasing progress on temporary vacancy Alexandria’s development and redevelopment pipeline delivered incremental annual net operating Strong and flexible balance sheet Subsequent event We will host a conference call on Tuesday, October 28, 2025, at 2:00 p.m. Eastern Time (“ET”)/11:00 a.m. Pacific Time (“PT”), which is open to the general public, to discuss our financial and operating The following table presents a reconciliation of net income (loss) attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in The following table presents a reconciliation of net income (loss) per share attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a Alexandria’s executive and senior management team consists of Corporate Headquarters New York Stock Exchange Trading Symbol Information Requests26 North Euclid Avenue Common stock: ARE Phone:(626) 578-0777Pasadena, California 91101 Email:corporateinformation@are.comwww.are.com Website:investor.are.com Stable Cash Flows From Our High-Quality and Diverse Mix of Approximately 700 TenantsInvestment-Grade or Publicly Traded Large Cap Tenants90%of ARE’s Top 20 Tenant Annual Rental Revenue53%of ARE’s TotalAnnual Rental Revenue Three Months EndedNine Months EndedYear EndedSeptember 30, 2025September 30, 2025December 31, 2024Including Straight-Line RentCash BasisIncluding Straight-Line RentCash BasisIncluding Straight-Line RentCash BasisLeasing activity:Renewed/re-leased space(1) Rental rate changes15.2%6.1%13.6%6.8%16.9%7.2%New rates$56.91$57.07$59.45$59.17$65.48$64.18Expiring rates$49.42$53.77$52.34$55.41$56.01$59.85RSF354,3671,722,1843,888,139Tenant improvements/leasing commissions$47.15$66.29$46.89Weighted-average lease term7.3 years9.5 years8.5 yearsPreviously vacant/developed/redeveloped space leased(2)New rates$85.31$76.33$74.93$69.16$59.44$57.34Previously vacant RSF256,633550,986672,474Developed/redeveloped RSF560,344(3)698,542493,341Weighted-average lease term15.4 years14.7 years10.0 yearsLeasing activity summary (totals):New rates$76.72$70.51$65.96$63.37$64.16$62.68RSF1,171,3442,971,7125,053,954Weighted-average lease term14.6 years12.6 years8.9 yearsLease expirations(1)Expiring rates$66.03$67.63$56.68$57.98$53.82$57.24RSF800,421(4)3,549,0525,005,638 90% of Top 20 Tenant Annual Rental Revenue Is From Investment-Grade Investments in real estate not be materially higher or lower than these expectations. Our guidance for 2025 is subject to a number of variables and uncertainties, including actions and changes in policy by the current U.S. administration Three Months Ended September 30,Nine Months Ended September 30,20252024$ Change% Change20252024$ Change% ChangeIncome from rentals:Same properties$430,646$451,763$(21,117)(4.7)%$1,330,669$1,353,855$(23,186)(1.7)%Non-same properties110,424127,806(17,382)(13.6)315,890383,949(68,059)(17.7)Rental revenues541,070579,569(38,499)(6.6)1,646,5591,737,804(91,245)(5.3)Same properties167,933165,5792,3541.4492,718460,69032,0287.0Non-same properties26,84630,596(3,750)(12.3)77,02687,963(10,937)(12.4)Tenant recoveries194,779196,175(1,396)(0.7)569,744548,65321,0913.8Income from rentals735,849775,744(39,895)(5.1)2,216,3032,286,457(70,154)(3.1)Same properties352386(34)(8.8)1,1271,058696.5Non-same properties15,74315,4772661.754,71239,93414,77837.0Other income16,09515,8632321.555,83940,99214,84736.2Same properties598,931617,728(18,797)(3.0)1,824,5141,815,6038,9110.5Non-same properties153,013173,879(20,866)(12.0)447,628511,846(64,218)(12.5)Total revenues751,944791,607(39,663)(5.0)2,272,1422,327,449(55,307)(2.4)Same properties199,051192,2296,8223.5587,333539,27148,0628.9Non-same properties40,18341,036(853)(2.1)102,729129,562(26,833)(20.7)Rental operations239,234233,2655,9692.6690,062668,83321,2293.2Same properties399,880425,499(25,619)(6.0)1,237,1811,276,332(39,151)(3.1)Non-same properties112,830132,843(20,013)(15.1)344,899382,284(37,385)(9.8)Net operating income$512,710$558,342$(45,632)(8.2)%(1)$1,582,080$1,658,616$(76,536)(4.6)%(1)Net operating income - same properties$399,880$425,499$(25,619)(6.0)%$1,237,181$1,276,332$(39,151)(3.1)%Straight-line rent revenue (8,019)(21,594)13,575(62.9)(19,703)(96,437)76,734(79.6)Amortization of acquired below-market leases and deferred revenue related to tenant-funded and -built landlord improvements(8,167)(7,739)(428)5.5(26,385)(24,055)(2,330)9.7Net operating income - same properties (cash basis)$383,694$396,166$(12,472)(3.1)%$1,191,093$1,155,840$35,2533.0% RSFNumber of PropertiesAnnual Rental RevenueMarketOperatingDevelopmentRedevelopmentTotal% of TotalTotal% of TotalPer RSFGreater Boston9,096,225583,4071,626,32211,305,95426%64$708,46435%$89.74San Francisco Bay Area7,525,945212,796344,9348,083,6751962421,5182167.18San Diego6,314,303648,516 - 6,962,8191668328,6381554.67Seattle3,178,029227,577 - 3,405,606845126,834644.29Maryland3,855,906 - - 3,855,906950157,213844.00Research Triangle3,648,703 - - 3,648,70393694,255527.22New York City742,700 - - 742,7002369,317394.97Texas1,646,187 - 73,2981,719,48541336,866228.02Canada979,575 - 56,3141,035,88921120,186122.83Non-cluster/other markets315,440 - - 315,4401912,195155.52Properties held for sale1,811,787 - - 1,811,78741453,266344.62North America39,114,8001,672,2962,100,86842,887,964100%375$2,028,752100%$58.943,773,164 311 Arsenal Street421 Park Drive401 Park Drive40, 50, and 60 Sylvan Road(1)Greater Boston/Cambridge/Inner SuburbsGreater Boston/FenwayGreater Boston/FenwayGreater Boston/Route 128333,758 RSF392,011 RSF137,675 RSF596,064 RSF Debt covenantsUnsecured Senior Notes PayableUnsecured Senior Line of CreditDebt Covenant Ratios(1)RequirementSeptember 30, 2025RequirementSeptember 30, 2025Total Debt to Total Assets≤ 60%32%≤ 60.0%33.6%Secured Debt to Total Assets≤ 40% - %≤ 45.0% - %Consolidated EBITDA to Interest Expense≥ 1.5x9.8x≥ 1.50x3.58xUnencumbered Total Asset Value to Unsecured Debt≥ 150%302%N/AN/AUnsecured Interest Coverage RatioN/AN/A≥ 1.75x8.54x As of 10/27/25As of 7/21/25Key Changesto MidpointKey AssumptionsLowHighLowHighOperating occupancy percentage in North America as of December 31, 202590.0%91.6%(1)90.9%92.5%90 bps reductionLease renewals and re-leasing of space:Rental rate changes7.0%15.0%9.0%17.0%200 bps reduction(2)Rental rate changes (cash basis)0.5%8.5%0.5%8.5%No changeSame property performance:Net operating income changes(4.7)%(2.7)%(3.7)%(1.7)%100 bps reductionNet operating income changes (cash basis)(1.2)%0.8%(1.2)%0.8%No changeStraight-line rent revenue$75$95$96$116$21 million reductionGeneral and administrative expenses$112$127$112$127No ChangeCapitalization of interest$320$350$320$350Interest expense$195$225$185$215$10 million increase(3)Realized gains on non-real estate investments(4)$100$120$100$130$5 million reduction CONFERENCE CALLINFORMATION:Tuesday, October 28, 20252:00 p.m. Eastern Time11:00 a.m. Pacific Time(833) 366-1125 or(412) 902-6738Ask to join the conference call for Alexandria Real Estate Equities, Inc.CONTACT INFORMATION:Alexandria Real Estate Equities, Inc.corporateinformation@are.comJOEL S. MARCUSExecutive Chairman &Founder PETER M. MOGLIAChief Executive Officer & Chief Investment OfficerMARC E. BINDAChief Financial Officer & Treasurer PAULA SCHWARTZManaging Director,Rx Communications Group(917) 633-7790 GAAP financial measures and the reasons why we use these supplemental measures of performance and believe they provide useful information to investors. Additional detail can be found in our most recent common stockholders common stockholders (continued) 99 Coolidge Avenue500 North Beacon Street and 4 Kingsbury Avenue(1)Greater Boston/Cambridge/Inner SuburbsGreater Boston/Cambridge/Inner Suburbs129,413 RSF248,018 RSF100% Occupancy92% Occupancy As of September 30, 2025Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsInvestments in real estate$4,103,608$99,393Cash, cash equivalents, and restricted cash160,6462,341Other assets445,47910,533Secured notes payable - (67,315)Other liabilities(230,757)(5,351)Redeemable noncontrolling interests(58,662) - $4,420,314$39,601 (loss) and non-real estate investments. Refer to “Investments” under “Definitions and reconciliations” in the Supplemental Information for additional details. ALEXANDRIA HAS THE LONGEST WEIGHTED-AVERAGE REMAINING DEBT TERM We expect to introduce 2026 guidance on December 3, 2025 at our Investor Day. The following is an initial summary of key items that are expected to impact 2026 results: Fixed-rate and variable-rate debtFixed-RateDebtVariable-Rate DebtTotalPercentageWeighted-AverageInterest Rate(1)Remaining Term(in years)Unsecured senior notes payable$12,044,999$ - $12,044,99988.6%3.90%12.6Unsecured senior line of credit(2) and commercial paper program(3) - 1,548,5421,548,54211.44.524.3(4)Total/weighted average$12,044,999$1,548,542$13,593,541100.0%3.97%11.6(4)Percentage of total debt88.6%11.4%100.0% related to the regulatory environment, life science funding, the U.S. Food and Drug Administration and National Institutes of Health, trade, and other areas. For additional discussion relating to risks and uncertainties results for the third quarter ended September 30, 2025. To participate in this conference call, dial (833) 366-1125 or (412) 902-6738 shortly before 2:00 p.m. ET/11:00 a.m. PT and ask the operator to join the call for 3Q25 and YTD 3Q25 Net Loss per Share - Diluted of $(1.38) and $(2.09), respectively; and income of $16 million commencing during 3Q25, with an additional $111 million of incremental 9/30/256/30/253/31/2512/31/249/30/24Assets Investments in real estate$31,743,917$32,160,600$32,121,712$32,110,039$32,951,777Investments in unconsolidated real estate joint ventures39,60140,23450,08639,87340,170Cash and cash equivalents579,474520,545476,430552,146562,606Restricted cash4,7057,4037,3247,70117,031Tenant receivables6,4096,2676,8756,4096,980Deferred rent1,257,3781,232,7191,210,5841,187,0311,216,176Deferred leasing costs505,241491,074489,287485,959516,872Investments1,537,6381,476,6961,479,6881,476,9851,519,327Other assets 1,700,7851,688,0911,758,4421,661,3061,657,189Total assets$37,375,148$37,623,629$37,600,428$37,527,449$38,488,128Liabilities, Noncontrolling Interests, and EquitySecured notes payable$ - $153,500$150,807$149,909$145,000Unsecured senior notes payable12,044,99912,042,60712,640,14412,094,46512,092,012Unsecured senior line of credit and commercial paper1,548,5421,097,993299,883 - 454,589Accounts payable, accrued expenses, and other liabilities2,432,7262,360,8402,281,4142,654,3512,865,886Dividends payable230,603229,686228,622230,263227,191Total liabilities16,256,87015,884,62615,600,87015,128,98815,784,678Commitments and contingenciesRedeemable noncontrolling interests58,6629,6129,61219,97216,510Alexandria Real Estate Equities, Inc.’s stockholders’ equity:Common stock1,7031,7011,7011,7221,722Additional paid-in capital16,669,80217,200,94917,509,14817,933,57218,238,438Accumulated other comprehensive loss(32,203)(27,415)(46,202)(46,252)(22,529)Alexandria Real Estate Equities, Inc.’s stockholders’ equity16,639,30217,175,23517,464,64717,889,04218,217,631Noncontrolling interests4,420,3144,554,1564,525,2994,489,4474,469,309Total equity21,059,61621,729,39121,989,94622,378,48922,686,940Total liabilities, noncontrolling interests, and equity$37,375,148$37,623,629$37,600,428$37,527,449$38,488,128 accordance with U.S. generally accepted accounting principles (“GAAP”), including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations accordance with GAAP, including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations per share attributable to Alexandria’s common best-in-class, mission-driven life science REIT making a positive and lasting impact on the Development and RedevelopmentUnder Construction100% Pre-leased Committed Near Term(1)Operating2025 and 2026 2027 and BeyondFutureSubtotalTotalSquare footageOperating37,303,013 - - - - - 37,303,013Future Class A/A+ development and redevelopment properties - 969,5242,803,640466,59824,257,78228,497,54428,497,544Future development and redevelopment square feet currently included in rental properties(2) - - - (52,620)(2,082,454)(2,135,074)(2,135,074)Total square footage, excluding properties held for sale37,303,013969,5242,803,640413,97822,175,32826,362,47063,665,483Properties held for sale1,811,787 - - - 939,756939,7562,751,543Total square footage39,114,800969,5242,803,640413,97823,115,08427,302,22666,417,026Investments in real estateGross book value as of September 30, 2025(3)$29,451,717$901,674$2,762,729$60,398$4,984,144$8,708,945(4)$38,160,662Properties held for sale883,455 - - - 112,681112,681996,136Total gross investment in real estate, excluding properties held for sale$28,568,262$901,674$2,762,729$60,398$4,871,463$8,596,264$37,164,526 Is Within Our Megacampus™ Ecosystems We present certain operating statistics related to our properties, including number of Unencumbered net operating income as a percentage of total net operating income is a non- Furthermore, we believe net operating income is useful to investors as a performance •Leasing volume of 1.2 million RSF during 3Q25. Net debt and preferred stock to Adjusted EBITDA is a non-GAAP financial measure that we Annual rental revenue represents the annualized fixed base rental obligations, calculated in Class A/A+ properties are properties clustered in AAA locations that provide innovative Initial stabilized yield is calculated as the estimated amounts of net operating income at The following table reconciles net income (loss) to net operating income and net operating The stabilized occupancy date represents the estimated date on which a development or From time to time, we enter into capital market transactions, including forward equity sales Operating occupancy as of June 30, 202590.8%Assets with vacancy designated as held for sale during 3Q25 now excluded from operating occupancy and expected to be sold primarily in 4Q250.9Reduction in occupancy, primarily from 3Q25 lease expirations(1.1)(1)Operating occupancy as of September 30, 202590.6Key vacant space leased with future delivery1.6(2)Operating occupancy as of September 30, 2025, including leased but not yet delivered space92.2% Key capital events •In October 2025, we completed dispositions aggregating $167.4 million across three Fixed-charge coverage ratio is a non-GAAP financial measure representing the ratio of 61 individuals averaging 24 years of real estate experience, annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, as well as other documents filed with or furnished to the SEC from time to time. Revenue-enhancing and repositioning capital expenditures represent spending to reposition The following table reconciles our investments in real estate as of September 30, 2025: The square footage presented in the table below is classified as operating as of We present components of balance sheet and operating results information related to our real We present a tabular comparison of items, whether gain or loss, that may facilitate a high- The following table reconciles the number of same properties to total properties for the nine Aggregated $68 Million,(1) Including $16 Million in 3Q25 We hold investments in publicly traded companies and privately held entities primarily that could cause actual results to differ materially from those anticipated, refer to our discussion of “forward-looking statements” on page 8 of the Earnings Press Release as well as our SEC filings, including our September 30, 2025Year Ended December 31, 2024Three Months EndedNine Months EndedRealized gains$9,646(1)$19,115(1)$59,124(2)Unrealized gains (losses)18,515(3)(71,568)(4)(112,246)(5)Investment income (loss)$28,161$(52,453)$(53,122) Alexandria Real Estate Equities, Inc. The audio webcast can be accessed at www.are.com in the “For Investors” section. A replay of the call will be available for a limited time from 4:00 p.m. ET/1:00 p.m. PT on 3Q25 and YTD 3Q25 FFO per Share - Diluted, as Adjusted, of $2.22 and $6.85, respectively annual net operating income anticipated to deliver by 4Q26 primarily from projects that are 80% attributable to Alexandria’s common stockholders - diluted, and funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted, for the periods below: stockholders - diluted, and funds from operations per share attributable to Alexandria’s common stockholders - diluted, as adjusted, for the periods below. Per share amounts may not add due to world. With our founding in 1994, Alexandria pioneered the life science real estate niche. properties, RSF, occupancy percentage, leasing activity, and contractual lease expirations as of the end GAAP financial measure that we believe is useful to investors as a performance measure of the results measure of our consolidated properties because, when compared across periods, net operating income or Publicly Traded Large Cap Tenants(1) believe is useful to investors as a supplemental measure of evaluating our balance sheet leverage. Net accordance with GAAP, including the amortization of deferred revenue related to tenant-funded and tenants with highly dynamic and collaborative environments that enhance their ability to successfully stabilization divided by our investment in the property. For this calculation, we exclude any tenant- income (cash basis) and computes operating margin: redevelopment project is expected to reach occupancy of 95% or greater. agreements (“Forward Agreements”), to fund acquisitions, to fund construction of our development and •Includes the largest life science lease in company history with a long-standing multinational Adjusted EBITDA to cash interest and fixed charges. We believe that this ratio is useful to investors as a GAAP-basis accounting for real estate assets utilizes historical cost accounting and assumes submarkets and recognized a gain on sales of real estate of $4.4 million. Refer to or significantly change the use of a property, including through improvement in the asset quality from The following table reconciles net income (loss) to funds from operations for the share of September 30, 2025. These lease expirations or vacant space at recently acquired properties represent estate joint ventures, which are not presented, or intended to be presented, in accordance with GAAP. level understanding of our results and provide context for the disclosures included in this Supplemental months ended September 30, 2025: •Core operations - Slower demand across the life science sector and increased supply for life science real estate could negatively impact future occupancy. Additional considerations involved in the life science industry. We recognize, measure, present, and disclose these investments as AMONG S&P 500 REITS AT 2X THE AVERAGE DEBT TERM FOR THESE REITS •In August 2025, we repaid a secured construction loan aggregating $154.6 million with an 0.4M RSFOPERATING 1.3M RSFOPERATING 0.7M RSFOPERATING 0.4M RSFOPERATING most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. Tuesday, October 28, 2025. The replay number is (877) 344-7529 or (412) 317-0088, and the access code is 6086829. including 13 years with Alexandria. Our executive management (In thousands)Investments in Real EstateGross investments in real estate$38,160,662Less: accumulated depreciation(6,416,745)Investments in real estate$31,743,917 of the period. We believe these measures are useful to investors because they facilitate an of operations of our unencumbered real estate assets as it reflects those income and expense items that leased/negotiating rounding. Alexandria is the preeminent and longest-tenured owner, operator, and developer of reflects trends in occupancy rates, rental rates, and operating costs, which provide a perspective not debt and preferred stock is equal to the sum of total consolidated debt less cash, cash equivalents, and tenant-built landlord improvements, for leases in effect as of the end of the period, related to our recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. These funded and tenant-built landlord improvements from our investment in the property. Our initial stabilized redevelopment projects, and for general working capital purposes. While the Forward Agreements are that real estate values diminish over time. In an effort to overcome the difference between real estate pharmaceutical tenant for a 16-year build-to-suit lease expansion aggregating MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionCommitted Near TermFutureTotal(1)Greater BostonMegacampus: Alexandria Center® at One Kendall Square/Cambridge100%$173,897104,956 - - 104,956One Hampshire StreetMegacampus: The Arsenal on the Charles/Cambridge/Inner Suburbs100%311,016333,758 - 34,157367,915 311 Arsenal StreetMegacampus: 480 Arsenal Way and 446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue/Cambridge/Inner Suburbs100%233,479191,396 - 560,000751,396446, 458, and 500 Arsenal Street, and 99 Coolidge AvenueMegacampus: Alexandria Center® for Life Science - Fenway/Fenway100%736,035529,686 - - 529,686401 and 421 Park DriveMegacampus: Alexandria Center® for Life Science - Waltham/Route 128100%576,242596,064 - 515,0001,111,06440, 50, and 60 Sylvan Road, and 35 Gatehouse DriveMegacampus: Alexandria Center® at Kendall Square/Cambridge100%212,439 - - 174,500174,500100 Edwin H. Land BoulevardMegacampus: Alexandria Technology Square®/Cambridge100%8,449 - - 100,000100,000Megacampus: 285, 299, 307, and 345 Dorchester Avenue/Seaport Innovation District60.0%295,345 - - 1,040,0001,040,00010 Necco Street/Seaport Innovation District100%106,373 - - 175,000175,000215 Presidential Way/Route 128100%6,816 - - 112,000112,000Other development and redevelopment projects100%379,674453,869 - 1,348,5411,802,410$3,039,7652,209,729 - 4,059,1986,268,927Refer to “Megacampus” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties. supplemental measure of our ability to satisfy fixed financing obligations and preferred stock dividends. Adjusted EBITDA and Adjusted EBITDA margin We believe Adjusted EBITDA provides investors with relevant and useful information as it Weighted-Average Remaining Term of 11.6 Years “Dispositions and exchange of partial interests” in the Earnings Press Release for additional Class B to Class A/A+. consolidated real estate joint ventures attributable to noncontrolling interests and our share of future opportunities for which we have the intent, subject to market conditions and leasing, to commence We present the proportionate share of certain financial line items as follows: (i) for each real estate joint Information, our most recent annual report on Form 10-K, and our subsequent quarterly reports on Form Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalGreater BostonCambridge/Inner SuburbsMegacampus: Alexandria Center® at Kendall Square2,213,867 - - 2,213,8678$212,82893.4%93.4%50(1), 60(1), 75/125(1), 90, 100(1), and 225(1) Binney Street, 140 First Street, and 300 Third Street(1)Megacampus: Alexandria Center® at One Kendall Square1,284,745 - 104,9561,389,70112148,64492.585.5One Kendall Square (Buildings 100, 200, 300, 400, 500, 600/700, 1400, 1800, and 2000), 325 and 399 Binney Street, and One Hampshire StreetMegacampus: Alexandria Technology Square®1,196,987 - - 1,196,987774,95772.972.9100, 200, 300, 400, 500, 600, and 700 Technology Square Megacampus: The Arsenal on the Charles787,760 - 333,7581,121,5181346,67878.054.8 311, 321, and 343 Arsenal Street, 300, 400, and 500 North Beacon Street, 1, 2, 3, and 4 Kingsbury Avenue, and 100, 200, and 400 Talcott AvenueMegacampus: 480 Arsenal Way, 446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue(1)386,780191,396 - 578,176519,97572.672.6Cambridge/Inner Suburbs5,870,139191,396438,7146,500,24945503,08285.679.6FenwayMegacampus: Alexandria Center® for Life Science - Fenway1,314,508392,011137,6751,844,1943100,66587.579.2401 and 421 Park Drive and 201 Brookline AvenueSeaport Innovation District5 and 15(1) Necco Street459,395 - - 459,395247,22697.097.0Seaport Innovation District459,395 - - 459,395247,22697.097.0Route 128Megacampus: Alexandria Center® for Life Science - Waltham466,094 - 596,0641,062,158538,531100.043.940, 50, and 60 Sylvan Road, 35 Gatehouse Drive, and 840 Winter Street19, 225, and 235 Presidential Way585,226 - - 585,226314,19497.097.0Route 1281,051,320 - 596,0641,647,384852,72598.362.8Other400,863 - 453,869854,73264,76659.728.0Greater Boston9,096,225583,4071,626,32211,305,95464$708,46486.8%73.6%Our Megacampus™ Properties Account for 77% of Our Annual Rental RevenueRefer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. follows: include the following: PASADENA, Calif. - October 27, 2025 - Alexandria Real Estate Equities, Inc. (NYSE: ARE) interest rate of 7.18%, which was secured by our development project at 99 Coolidge Avenue Three Months EndedNine Months Ended(Dollars in thousands)9/30/259/30/249/30/259/30/24Net (loss) income$(197,845)$213,603$(221,372)$526,828Equity in (earnings) losses of unconsolidated real estate joint ventures(201)(139)9,327(424)General and administrative expenses29,22443,94589,027135,629Interest expense54,85243,550161,024130,179Depreciation and amortization340,230293,9981,028,415872,272Impairment of real estate323,8705,741485,63036,504Loss on early extinguishment of debt107 - 107 - Gain on sales of real estate(9,366)(27,114)(22,531)(27,506)Investment (income) loss(28,161)(15,242)52,453(14,866)Net operating income512,710558,3421,582,0801,658,616Straight-line rent revenue(18,821)(29,087)(59,380)(125,676)Amortization of deferred revenue related to tenant-funded and -built landlord improvements(5,455)(329)(9,507)(329)Amortization of acquired below-market leases(6,456)(17,312)(31,874)(70,167)Provision for expected credit losses on financial instruments - - 285 - Net operating income (cash basis)$481,978$511,614$1,481,604$1,462,444Net operating income (cash basis) - annualized$1,927,912$2,046,456$1,975,472$1,949,925Net operating income (from above)$512,710$558,342$1,582,080$1,658,616Total revenues$751,944$791,607$2,272,142$2,327,449Operating margin68%71%70%71% understanding of certain trends for our properties. We compute the number of properties, RSF, Redevelopment - placed intoDevelopment - under constructionPropertiesservice after January 1, 2024Properties99 Coolidge Avenue1840 Winter Street11450 Owens Street1Alexandria Center® for Advanced Technologies - Monte Villa Parkway610075 Barnes Canyon Road1421 Park Drive174135 Campus Point Court1Acquisitions after January 1, 2024Properties701 Dexter Avenue North1Other363Development - placed intoUnconsolidated real estate JVs4service after January 1, 2024PropertiesProperties held for sale149810 Darnestown Road1Total properties excluded from same properties619820 Darnestown Road11150 Eastlake Avenue East1Same properties3144155 Campus Point Court1Total properties in North America as of September 30, 2025375201 Brookline Avenue19808 Medical Center Drive1230 Harriet Tubman Way1500 North Beacon Street and 4 Kingsbury Avenue210935, 10945, and 10955 Alexandria Way312Redevelopment - under constructionProperties40, 50, and 60 Sylvan Road3269 East Grand Avenue1651 Gateway Boulevard1401 Park Drive18800 Technology Forest Place1311 Arsenal Street1One Hampshire Street1Canada4Other215 are incurred at the unencumbered property level. Unencumbered net operating income is derived from Key changes to our 2025 guidance include the following: immediately apparent from net income or loss. Net operating income can be used to measure the initial Three Months EndedNine Months Ended9/30/256/30/253/31/2512/31/249/30/249/30/259/30/24Net (loss) income attributable to Alexandria’s common stockholders - basic and diluted$(234,937)$(109,611)$(11,599)$(64,922)$164,674$(356,147)$374,477Depreciation and amortization of real estate assets338,182343,729339,381327,198291,2581,021,292864,326Noncontrolling share of depreciation and amortization from consolidated real estate JVs(45,327)(36,047)(33,411)(34,986)(32,457)(114,785)(94,725)Our share of depreciation and amortization from unconsolidated real estate JVs8529421,0541,0611,0752,8483,177Gain on sales of real estate(9,824)(1) - (13,165)(100,109)(27,114)(22,989)(27,506)Impairment of real estate - rental properties and land323,870(2)131,090 - 184,5325,741454,9607,923Allocation to unvested restricted stock awards (1,648)(1,222)(686)(1,182)(2,908)(3,590)(7,657)Funds from operations attributable to Alexandria’s common stockholders - diluted(3)371,168328,881281,574311,592400,269981,5891,120,015Unrealized (gains) losses on non-real estate investments(18,515)21,93868,14579,776(2,610)71,56832,470Impairment of non-real estate investments25,139(4)39,21611,18020,26610,33875,53537,824Impairment of real estate - 7,18932,1542,032 - 39,34328,581Loss on early extinguishment of debt107 - - - - 107 - Increase (decrease) in provision for expected credit losses on financial instruments - - 285(434) - 285 - Allocation to unvested restricted stock awards(74)(794)(1,329)(1,407)(125)(2,156)(1,640)Funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted$377,825$396,430$392,009$411,825$407,872$1,166,271$1,217,250 Three Months EndedNine Months Ended9/30/256/30/253/31/2512/31/249/30/249/30/259/30/24Net (loss) income per share attributable to Alexandria’s common stockholders - diluted$(1.38)$(0.64)$(0.07)$(0.38)$0.96$(2.09)$2.18Depreciation and amortization of real estate assets1.731.811.801.701.515.344.49Gain on sales of real estate(0.06) - (0.08)(0.58)(0.16)(0.14)(0.16)Impairment of real estate - rental properties and land1.900.77 - 1.070.032.670.05Allocation to unvested restricted stock awards(0.01)(0.01) - - (0.01)(0.02)(0.05)Funds from operations per share attributable to Alexandria’s common stockholders - diluted2.181.931.651.812.335.766.51Unrealized (gains) losses on non-real estate investments(0.11)0.130.400.46(0.02)0.420.19Impairment of non-real estate investments0.150.230.070.120.060.450.22Impairment of real estate - 0.040.190.01 - 0.230.17Allocation to unvested restricted stock awards - - (0.01)(0.01) - (0.01)(0.01)Funds from operations per share attributable to Alexandria’s common stockholders - diluted, as adjusted$2.22$2.33$2.30$2.39$2.37$6.85$7.08Weighted-average shares of common stock outstanding - dilutedEarnings per share - diluted170,181170,135170,522172,262172,058170,278172,007Funds from operations - diluted, per share170,305170,192170,599172,262172,058170,351172,007Funds from operations - diluted, as adjusted, per share170,305170,192170,599172,262172,058170,351172,007 collaborative Megacampus™ ecosystems in AAA life science innovation cluster locations, restricted cash, plus preferred stock outstanding as of the end of the period. Refer to the definition of operating RSF. Annual rental revenue is presented using 100% of the annual rental revenue from our properties are typically well-located, professionally managed, and well-maintained, offering a wide range yield excludes the benefit of leverage. Our cash rents related to our development and redevelopment Tenant recoveries outstanding, we are required to consider the potential dilutive effect of our Forward Agreements under values and historical cost accounting for real estate assets, the Nareit Board of Governors established Cash interest is equal to interest expense calculated in accordance with GAAP plus capitalized interest, allows investors to evaluate the operating performance of our business activities without having to 466,598 RSF, located on the Campus Point by Alexandria Megacampus in our University team alone averages 19 years with Alexandria. unconsolidated real estate joint ventures: first-time conversion from non-laboratory space to laboratory space, or to commence future ground-up venture that we consolidate in our financial statements, which are controlled by us through contractual 10-Q. We believe that such tabular presentation promotes a better understanding for investors of the •During 3Q25, we placed into service development projects aggregating 185,517 RSF that are details. Statements of OperationsBalance SheetGains and LossesCarrying AmountUnrealizedRealizedDifference between proceeds received upon disposition and historical costPublicly traded companiesFair valueChanges in fair valuePrivately held entities without readily determinable fair values that:Report NAVFair value, using NAV as a practical expedientChanges in NAV, as a practical expedient to fair valueDo not report NAVCost, adjusted for observable price changes and impairments(1)Observable price changes(1)Impairments to reduce costs to fair value, which result in an adjusted cost basis and the differences between proceeds received upon disposition and adjusted or historical costEquity method investmentsContributions, adjusted for our share of the investee’s earnings or losses, less distributions received, reduced by other-than-temporary impairments Our share of unrealized gains or losses reported by the investeeOur share of realized gains or losses reported by the investee, and other-than-temporary impairments •Same property net operating income decrease for 3Q25 compared to 3Q24 of 6.0% reflects a decline relative to the first half of 2025. Refer to “Same property performance” in the Additionally, a copy of this Earnings Press Release and Supplemental Information for the third quarter ended September 30, 2025 is available in the “For Investors” section of our website at www.are.com announced financial and operating results for the third quarter ended September 30, 2025. in our Cambridge/Inner Suburbs submarket. The project is currently 81% leased/negotiating ALEXANDRIA’S DEVELOPMENT AND REDEVELOPMENT DELIVERIES ARE EXPECTED TO PROVIDE INCREMENTAL GROWTH IN ANNUAL NET OPERATING INCOME The following table reconciles net income (loss), the most directly comparable financial occupancy percentage, leasing activity, and contractual lease expirations at 100%, excluding RSF at assets classified in continuing operations, which are not subject to any mortgage, deed of trust, lien, or stabilized yields of our properties by calculating net operating income generated by a property divided by funds from operations as an improved measurement tool. Since its introduction, funds from operations Adjusted EBITDA and Adjusted EBITDA margin for further information on the calculation of Adjusted consolidated properties and our share of annual rental revenue for our unconsolidated real estate joint of amenities and featuring premium construction materials and finishes. Class A/A+ properties are projects are generally expected to increase over time due to contractual annual rent escalations. Our the treasury stock method. Under this method, we also include the dilutive effect of unvested restricted including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland, TenantRemaining Lease Term(1) (in years)Aggregate RSFAnnual Rental Revenue(1)Percentage of Annual Rental Revenue(1)Investment-Grade Credit RatingsAverage Market Cap(in billions)Moody’sS&P1Bristol-Myers Squibb Company5.71,283,860$110,8655.5%A2A$106.52Eli Lilly and Company9.11,086,16590,8054.5Aa3A+$753.23Moderna, Inc.13.2462,10071,5713.5 - - $13.34Takeda Pharmaceutical Company Limited9.7549,75947,8992.4Baa1BBB+$45.65AstraZeneca PLC6.4440,08739,4131.9A1A+$223.06Eikon Therapeutics, Inc.(2)13.3311,80638,9131.9 - - $ - 7Roche7.5647,06936,3831.8Aa2AA$256.88Illumina, Inc.5.1857,96735,9241.8Baa3BBB$17.19Alphabet Inc.2.2589,21833,2601.6Aa2AA+$2,231.610United States Government4.8429,35929,597(3)1.5AaaAA+$ - 11Novartis AG2.3377,09529,4631.5Aa3AA-$240.212Uber Technologies, Inc.57.0(4)1,009,18827,8201.4Baa1BBB$167.113Boston Children's Hospital11.5309,23126,2941.3Aa2AA$ - 14The Regents of the University of California9.7364,60624,3181.2Aa2AA$ - 15Sanofi5.3267,27821,8511.1Aa3AA$127.116New York University6.8218,98321,1101.0Aa2AA-$ - 17Merck & Co., Inc.7.9333,12421,0011.0Aa3A+$225.818Charles River Laboratories, Inc.9.8253,03620,9591.0 - - $8.219Cloud Software Group, Inc.1.0(5)216,27820,5531.0 - - $ - 20Massachusetts Institute of Technology4.3242,42820,5291.0AaaAAA$ - Total/weighted-average9.4(4)10,248,637$768,52837.9% less amortization of loan fees and debt premiums (discounts). account for differences recognized because of investing and financing decisions related to our real 1)The midpoint of our guidance range for 2025 net (loss) income per share was reduced by $3.44 from $0.50 to $(2.94). In addition to the items discussed in item 2 below, the update to our guidance range Town Center submarket. Non-revenue-enhancing capital expenditures represent costs required to maintain the current development: rights or majority voting rights, but of which we own less than 100%, we apply the noncontrolling interest $87MREDUCTION IN ANNUAL NETOPERATING INCOME(1)FROM 2025 DISPOSITIONS(2)32 TOTAL TRANSACTIONS(2)$1.5BTOTAL SALES(2) corporate-level decisions made and activities performed that significantly affect comparison of our 89% occupied across multiple submarkets and delivered incremental annual net operating or by following this link: https://www.are.com/fs/2025q3.pdf. Supplemental Information for additional details. Property/Market/SubmarketOur Ownership InterestRSF Placed in ServiceOccupancy Percentage(3)Total ProjectUnlevered Yields3Q25 Delivery Date(2)Prior to 1/1/251Q252Q253Q25TotalInitial StabilizedInitial Stabilized (Cash Basis)RSFInvestmentDevelopment projects99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs7/15/25100%116,414 - - 12,999129,413100%320,809$444,0006.0%6.8%500 North Beacon Street and 4 Kingsbury Avenue/Greater Boston/Cambridge/Inner Suburbs8/23/25100%211,574 - - 36,444248,01892%248,018429,0006.55.9230 Harriet Tubman Way/San Francisco Bay Area/South San FranciscoN/A48.5% - 285,346 - - 285,346100%285,346476,0007.56.210935, 10945, and 10955 Alexandria Way/San Diego/Torrey Pines7/1/25100%93,492 - 119,202122,302334,996100%334,996480,0007.26.910075 Barnes Canyon Road/San Diego/Sorrento Mesa7/23/2550.0% - 17,718 - 13,77231,490100%253,079321,0005.55.7Redevelopment projects651 Gateway Boulevard/San Francisco Bay Area/South San FranciscoN/A50.0%67,017 - 22,005 - 89,02275%326,706487,0005.05.1CanadaN/A100%78,4876,43076,567 - 161,484100%250,790115,0006.06.0Weighted average/total7/5/25566,984309,494217,774185,5171,279,7692,019,744$2,752,0006.3%6.1% Tenant recoveries represent revenues comprising reimbursement of real estate taxes, and is expected to be delivered in 4Q26. In connection with the repayment, we recognized a measure calculated and presented in accordance with GAAP, to Adjusted EBITDA and calculates the Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsSeptember 30, 2025September 30, 2025(In thousands)Three Months EndedNine Months EndedThree Months EndedNine Months EndedNet income (loss)$34,909$127,323$201$(9,327)Depreciation and amortization of real estate assets45,327114,7858522,848Gain on sale of interest of unconsolidated JV - - (458)(458)Impairment of real estate - - - 8,673Funds from operations$80,236$242,108$595$1,736 properties classified as held for sale, for all properties in which we have an investment, including other security interest, as of the period for which income is presented. our investment in the property. Net operating income excludes certain components from net income in has become a widely used non-GAAP financial measure among equity REITs. We believe that funds EBITDA. ventures. Annual rental revenue per RSF is computed by dividing annual rental revenue by the sum of generally newer or have undergone substantial redevelopment and are generally expected to command estimates for initial stabilized yields, initial stabilized yields (cash basis), and total costs at completion stock awards (“RSAs”) with forfeitable dividends in the calculation of diluted shares. Key highlightsYTDOperating results3Q253Q243Q253Q24Net (loss) income attributable to Alexandria’s common stockholders - diluted:In millions$(234.9)$164.7$(356.1)$374.5Per share$(1.38)$0.96$(2.09)$2.18Funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted:In millions$377.8$407.9$1,166.3$1,217.3Per share$2.22$2.37$6.85$7.08 Research Triangle, and New York City. for 2025 net (loss) income per share includes the following: estate and non-real estate investments, our capital structure, capital market transactions, and variances revenues of a stabilized property, including the associated costs for renewed and re-leased space. economic ownership percentage to each financial item to arrive at the amount of such cumulative operating results from period to period. We also believe that this tabular presentation will supplement for •Leasing of previously vacant space aggregating 256,633 RSF, up 40%, over the quarterly EXECUTIVE MANAGEMENT TEAMJoel S. MarcusPeter M. MogliaExecutive Chairman & FounderChief Executive Officer & Chief Investment OfficerDaniel J. RyanHunter L. KassCo-President & Regional Market Director - San DiegoCo-President & Regional Market Director - Greater BostonMarc E. BindaLawrence J. DiamondChief Financial Officer & TreasurerCo-Chief Operating Officer & Regional Market Director - MarylandJoseph HakmanHart ColeCo-Chief Operating Officer & Chief Strategic Transactions OfficerExecutive Vice President - Capital Markets/Strategic Operations & Co-Regional Market Director - SeattleJackie B. ClemGary D. DeanGeneral Counsel & SecretaryExecutive Vice President - Real Estate Legal AffairsAndres R. GavinetOnn C. LeeChief Accounting OfficerExecutive Vice President - AccountingKristina A. Fukuzaki-CarlsonMadeleine T. AlsbrookExecutive Vice President - Business OperationsExecutive Vice President - Talent Management Dev/RedevRSF of Lease Expirations Targeted forDevelopment and RedevelopmentProperty/Submarket20252026Thereafter(1)TotalCommitted near-term project:Campus Point by Alexandria/University Town CenterDev - 52,620 - 52,620Future projects:446, 458, and 500 Arsenal Street/Cambridge/Inner SuburbsDev - - 116,623116,623Other/Greater BostonRedev - - 167,549167,5491122 and 1150 El Camino Real/South San FranciscoDev - - 375,232375,2323875 Fabian Way/Greater StanfordDev - - 228,000228,0002100 and 2200 Geng Road/Greater Stanford Dev - - 62,52662,526960 Industrial Road/Greater StanfordDev - - 112,590112,590Campus Point by Alexandria/University Town CenterDev - - 96,80596,805Sequence District by Alexandria/Sorrento MesaDev/Redev - - 555,754555,754410 West Harrison Street/Elliott BayDev - - 17,20517,205Other/SeattleDev - - 63,05763,057100 Capitola Drive/Research Triangle Dev - - 39,37039,370CanadaRedev - - 247,743247,743 - - 2,082,4542,082,454Total - 52,6202,082,4542,135,074 income of $16 million. •Operating occupancy has decreased four consecutive quarters from 94.7% as of September 30, 2024 to 90.6% as of September 30, 2025. insurance, utilities, repairs and maintenance, common area expenses, and other operating expenses Life Science Product, Service, and Device 1.4M RSFACTIVE/FUTURE loss on early extinguishment of debt of $107 thousand for the write-off of unamortized Adjusted EBITDA margin: properties owned by our consolidated and unconsolidated real estate joint ventures. For operating from operations is helpful to investors as an additional measure of the performance of an equity order to provide results that are more closely related to the results of operations of our properties. For 100% of the RSF of our consolidated properties and our share of the RSF of properties held in higher annual rental rates compared to other classes of similar properties. AAA locations are in close represent our initial estimates at the commencement of the project. We expect to update this information 2019 - YTD 3Q25AGGREGATE$10BTotal Proceeds(1)$3.6BTotal Gains onSales of Real Estate(2)$1.4BTotal Impairmentsof Real Estate(2) 1.9M RSFFUTURE 1.3M RSFACTIVE/FUTURE 1.5M RSFFUTURE The following table reconciles interest expense, the most directly comparable financial resulting from the volatility of market conditions outside of our control. For example, we exclude gains or For any questions, please contact corporateinformation@are.com; Joel S. Marcus, executive chairman and founder; Peter M. Moglia, chief executive officer and chief investment officer; Marc E. Binda, noncontrolling interest share of each component presented; and (ii) for each real estate joint venture that investors an understanding of our disclosures and real estate operating results. Gains or losses on sales average over the last five quarters. •Potential additional impairments of real estate (including impairments on stabilized and non-stabilized properties and land) that may be recognized in 4Q25 ranging from $0 to $685 million, related to •A significant 3Q25 delivery consisted of 122,302 RSF at 10935, 10945, and 10955
- Before the benefit of excluding assets designated as held for sale which contained vacancy, 3Q25 occupancy declined 1.1% compared to 2Q25, primarily related to 3Q25 lease and earned in the period during which the applicable expenses are incurred and the tenant’s obligation Equity Research Coverage deferred financing costs in 3Q25. The following table reconciles debt to net debt and preferred stock and computes the ratio to REIT. Moreover, we believe that funds from operations, as adjusted, allows investors to compare our metrics based on annual rental revenue, refer to the definition of annual rental revenue herein. The following table summarizes unencumbered net operating income as a percentage of total example, interest expense is not necessarily linked to the operating performance of a real estate asset Multinational Pharmaceutical unconsolidated real estate joint ventures. As of September 30, 2025, approximately 91% of our leases proximity to concentrations of specialized skills, knowledge, institutions, and related businesses. It is upon completion of the project, or sooner if there are significant changes to the expected project yields The weighted-average shares of common stock outstanding used in calculating EPS - diluted, measure calculated and presented in accordance with GAAP, to cash interest and computes fixed- losses on the early extinguishment of debt to allow investors to measure our performance independent The charts below present our reported same property results (“As reported”), which reflect the operating performance of all consolidated properties that were fully operational throughout the chief financial officer and treasurer; or Paula Schwartz, managing director of Rx Communications Group, at (917) 633-7790. As of September 30, 2025, Alexandria has a total market capitalization of Dividend payout ratio (common stock) we do not control and do not consolidate, which are instead controlled jointly or by our joint venture of real estate and impairments of assets classified as held for sale are related to corporate-level assets that could potentially be sold in 4Q25 or 2026, and if such assets meet the held for sale criteria in 4Q25, considering market factors, buyer ability to perform, our desire to proceed with a sale at •Rental rate increases on lease renewals and re-leasing of space of 15.2% and 6.1% (cash Three Months Ended(Dollars in thousands)9/30/256/30/253/31/2512/31/249/30/24Net (loss) income$(197,845)$(62,189)$38,662$(16,095)$213,603Interest expense54,85255,29650,87655,65943,550Income taxes3,7371,0201,1451,8551,877Depreciation and amortization340,230346,123342,062330,108293,998Stock compensation expense10,29312,53010,06412,47715,525Loss on early extinguishment of debt107 - - - - Gain on sales of real estate(9,366) - (13,165)(101,806)(27,114)Unrealized (gains) losses on non-real estate investments(18,515)21,93868,14579,776(2,610)Impairment of real estate323,870129,60632,154186,5645,741Impairment of non-real estate investments25,13939,21611,18020,26610,338Increase (decrease) in provision for expected credit losses on financial instruments - - 285(434) - Adjusted EBITDA$532,502$543,540$541,408$568,370$554,908Total revenues$751,944$762,040$758,158$788,945$791,607Adjusted EBITDA margin71%71%71%72%70% Alexandria Way on the One Alexandria Square Megacampus in our Torrey Pines to reimburse us arises. expirations. These lease expirations resulting in the 1.1% decline in occupancy previously generated annual rental revenue aggregating approximately $29.0 million and had a September 30, 2025December 31, 2024InvestmentsCostUnrealized GainsUnrealized LossesCarrying AmountCarrying AmountPublicly traded companies$197,229$28,964$(101,901)$124,292$105,667Entities that report NAV482,73498,002(40,603)540,133609,866Entities that do not report NAV:Entities with observable price changes80,45453,409(9,614)124,249174,737Entities without observable price changes422,519 - - 422,519400,487Investments accounted for under the equity method N/AN/AN/A326,445186,228September 30, 2025$1,182,936(6)$180,375$(152,118)$1,537,638$1,476,985December 31, 2024$1,207,146$228,100$(144,489)$1,476,985 performance to the performance of other real estate companies on a consistent basis, without having to Adjusted EBITDA: ALEXANDRIA net operating income: and is often incurred at the corporate level rather than at the property level. In addition, depreciation and (on an annual rental revenue basis) were triple net leases, which require tenants to pay substantially all important to note that our definition of property classification may not be directly comparable to other or costs. FFO per share - diluted, and FFO per share - diluted, as adjusted, during each period are calculated as charge coverage ratio: of our indebtedness and capital structure. We believe that adjusting for the effects of impairments and comparative quarterly periods presented. To provide additional insight and a retrospective view of the performance of our ongoing operating portfolio, the charts also present an alternative calculation of our partners through contractual rights or majority voting rights, we apply our economic ownership S&P 500 REITS(excluding Alexandria) decisions to dispose of real estate. Gains or losses on early extinguishment of debt are related to $27.8 billion and an asset base in North America that includes 39.1 million RSF of a particular price, and other factors. Investments basis) for 3Q25 and 13.6% and 6.8% (cash basis) for YTD 3Q25. Alexandria is currently covered by the following research analysts. This list may be incomplete and is subject to change as firms initiate or discontinue coverage of our company. Please note that any opinions, estimates, or forecasts regarding our historical or predicted performance made by these analysts are theirs alone and do not represent opinions, estimates, or forecasts of Alexandria or our management. Alexandria does not by our reference or distribution of the information below imply our endorsement of or concurrence with any opinions, estimates, or forecasts of these analysts. Interested persons may obtain copies of analysts’ reports on their own as we do not distribute these reports. Several of these firms may, from time to time, own our stock and/or hold other long or short positions in our stock and may provide compensated services to us. submarket. Stabilized Properties weighted-average lease expiration date at the end of July 2025. We are currently marketing these spaces. account for differences recognized because of real estate acquisition and disposition decisions, Same property comparisons Three Months Ended(Dollars in thousands)9/30/256/30/253/31/2512/31/249/30/24Unencumbered net operating income$512,710$535,766$530,691$547,921$553,589Encumbered net operating income - 1,8411,0725924,753Total net operating income$512,710$537,607$531,763$548,513$558,342Unencumbered net operating income as a percentage of total net operating income100.0%99.7%99.8%99.9%99.1% amortization, because of historical cost accounting and useful life estimates, may distort comparability of The following table presents our new Class A/A+ development and redevelopment pipeline, real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other equity REITs. Dividend payout ratio (common stock) is the ratio of the absolute dollar amount of dividends follows. Also shown are the weighted-average unvested shares associated with unvested RSAs with gains or losses on sales of real estate, significant impairments and realized gains or losses on non-real same property performance, using the 3Q25 same property pool (“3Q25 same properties”) for each period presented. We believe this alternative presentation provides a useful operating trend primarily by Land About the Company •Potential additional gain on sales of real estate that may be recognized in 4Q25 ranging from $0 to $240 million related to assets that may be sold in 4Q25. percentage to each financial item to arrive at our proportionate share of each component presented. corporate-level financing decisions focused on our capital structure strategy. Significant realized and operating properties and 4.2 million RSF of Class A/A+ properties undergoing construction (Dollars in thousands)9/30/256/30/253/31/2512/31/249/30/24Secured notes payable$ - $153,500$150,807$149,909$145,000Unsecured senior notes payable 12,044,99912,042,60712,640,14412,094,46512,092,012Unsecured senior line of credit and commercial paper1,548,5421,097,993299,883 - 454,589Unamortized deferred financing costs76,38378,57480,77677,64979,610Cash and cash equivalents(579,474)(520,545)(476,430)(552,146)(562,606)Restricted cash(4,705)(7,403)(7,324)(7,701)(17,031)Preferred stock - - - - - Net debt and preferred stock$13,085,745$12,844,726$12,687,856$11,762,176$12,191,574Adjusted EBITDA: - quarter annualized$2,130,008$2,174,160$2,165,632$2,273,480$2,219,632 - trailing 12 months$2,185,820$2,208,226$2,218,722$2,228,921$2,184,298Net debt and preferred stock to Adjusted EBITDA: - quarter annualized6.1x5.9x5.9x5.2x5.5x - trailing 12 months6.0x5.8x5.7x5.3x5.6x •82% of our leasing activity during the last twelve months was generated from our existing •Initial stabilized yield reflects rental income, including contractual rent escalations and any rent We classify rental revenues and tenant recoveries generated through the leasing of real •Annual net operating income (cash basis) from recently delivered projects is expected to 20% to 30% financing decisions, capital structure, capital market transactions, variances resulting from the volatility Three Months Ended(Dollars in thousands)9/30/256/30/253/31/2512/31/249/30/24Adjusted EBITDA$532,502$543,540$541,408$568,370$554,908Interest expense$54,852$55,296$50,876$55,659$43,550Capitalized interest86,09182,42380,06581,58686,496Amortization of loan fees(4,505)(4,615)(4,691)(4,620)(4,222)Amortization of debt discounts(325)(335)(349)(333)(330)Cash interest and fixed charges$136,113$132,769$125,901$132,292$125,494Fixed-charge coverage ratio: - quarter annualized3.9x4.1x4.3x4.3x4.4x - trailing 12 months4.1x4.3x4.4x4.5x4.5x •As of September 30, 2025: •Our guidance for operating occupancy percentage in North America as of December 31, 2025 assumes an approximate 1% benefit related to a range of assets with vacancy that (1)Comprises the following: (i) 0.3% related to lease expirations that became vacant in 3Q25 and have been re- operating performance at the property level. Impairments of real estate have been excluded in deriving excluding properties held for sale, as a percentage of gross assets and as a percentage of annual rental operating expenses (including increases thereto) in addition to base rent. Annual rental revenue on our common stock (shares of common stock outstanding on the respective record dates multiplied by nonforfeitable dividends used in calculating amounts allocable to these awards pursuant to the two-class estate investments, changes in provision for expected credit losses on financial instruments, and 20% to 30% 5.8 Years Average Debt Term of S&P 500 REITs as of June 30, 2025 removing properties expected to be sold. •These potential impairments and gains on sales of real estate will not impact our funds from operations per share pursuant to the Nareit definition of funds from operations. unrealized gains or losses on non-real estate investments, impairments of real estate and non-real and one 100% pre-leased committed near-term project expected to commence As a result of changes within our total property portfolio during the comparative periods Our long-term lease with a high-credit tenant underscores the strength and uniqueness of the Alexandria brand, as underpinned by:•Enduring tenant relationships and commitment to innovation•Expertise in design, development, and operations•Our Megacampus platform supporting tenant growth and talent recruitment and retention tenant base. concessions over the term(s) of the lease(s), calculated on a straight-line basis, and any estate assets within revenues in income from rentals in our consolidated statements of operations. We of market conditions outside of our control, or other corporate activities that may not be representative of increase by $50 million upon the burn-off of initial free rent, which has a weighted-average leased with a future delivery upon completion of construction (and is included in item 2 below); (ii) 0.2% •Our non-real estate investments aggregated $1.5 billion. Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a best-in-class, mission-driven life science REIT making a positive and lasting impact on the world. With our founding in 1994, could potentially qualify for designation as held for sale by December 31, 2025, but that have not yet qualified as of September 30, 2025. After considering this potential adjustment, The components of balance sheet and operating results information related to our real estate Credit ratings net operating income because we do not consider impairments of real estate to be property-level revenue as of September 30, 2025: excludes these operating expenses recovered from our tenants. Amounts recovered from our tenants the related dividend per share) to funds from operations attributable to Alexandria’s common method for each of the respective periods presented below. significant termination fees allows investors to evaluate performance from period to period on a estate investments, and acceleration of stock compensation expense due to the resignation of an (1)All covenant ratio titles utilize terms as defined in the respective debt and credit agreements. The calculation of consolidated EBITDA is based on the definitions contained in our loan agreements and is not directly comparable to (1)Represents the weighted-average interest rate as of the end of the applicable period, including expense/income related to the amortization of loan fees, amortization of debt premiums (discounts), and other bank fees. (3.1)% construction in the next year. 2)The midpoint of our guidance range for 2025 funds from operations per share - diluted, as adjusted, was reduced by 25 cents, from $9.26 to $9.01. The primary drivers of the change include the following: presented, including changes from assets acquired or sold, properties placed into development or amortization of deferred revenue related to tenant-funded and tenant-built landlord improvements. provide investors with a separate presentation of rental revenues and tenant recoveries in “Same 3Q25YTD 3Q25Lease renewals and re-leasing of space:Rental rate increase15.2%13.6%Rental rate increase (cash basis)6.1%6.8%RSF354,3671,722,184Leasing of previously vacant space - RSF256,633550,986Leasing of development and redevelopment space - RSF560,344698,542Total leasing activity - RSF1,171,3442,971,712 the operating performance of our properties. vacancy at one asset in our Greater Stanford submarket, which was recently acquired with the intent to remaining period of approximately three months. Alexandria pioneered the life science real estate niche. Alexandria is the preeminent and longest-tenured owner, operator, and developer of collaborative Megacampus™ ecosystems in AAA life science innovation SIGNIFICANTLIQUIDITYPERCENTAGE OF FIXED-RATE DEBT SINCE 2021(1)$4.2B96.7%REMAINING DEBT TERM(IN YEARS)DEBT INTEREST RATE11.63.97%Longest Among S&P 500 REITs(3)
- Unrealized gains presented in our consolidated balance sheet were $28.3 million, joint ventures do not represent our legal claim to those items. For each entity that we do not wholly own, operating expenses. Impairments of real estate relate to changes in the values of our assets and do not the midpoint of our guidance range for occupancy as of December 31, 2025 implies an 80 bps decline in operating occupancy percentage during 4Q25. related to these operating expenses, along with base rent, are classified in income from rentals in our stockholders - diluted, as adjusted. Percentage of(Dollars in thousands)Book ValueGross AssetsAnnual Rental RevenueProjects under active construction and one 100% pre-leased committed near-term project expected to commence in the next year$3,724,8019% - %Future development projects(1) and land parcels primarily located in Megacampuses4,871,463111$8,596,26420%1% consistent basis without having to account for differences recognized because of investing and financing the computation of EBITDA as described in Exchange Act Release No. 47226. (2)As of September 30, 2025, we had no outstanding balance on our unsecured senior line of credit. Same Property - Net Operating Income Same Property - Net Operating Income (Cash Basis) NBI TSR1,441% executive officer are not related to the operating performance of our real estate assets as they result redevelopment, and development or redevelopment properties recently placed into service, the redevelop office to laboratory space but for which we are now evaluating options to reposition for advanced •Initial stabilized yield (cash basis) reflects cash rents at the stabilization date after initial rental LARGEST, HIGHEST-QUALITYASSET BASE CLUSTERED IN THE KEY CENTERS OF LIFE SCIENCE INNOVATIONSECTOR-LEADING CLIENT BASE OF ~700 TENANTSHIGH-QUALITY CASH FLOWSPROVEN UNDERWRITINGFORTRESS BALANCE SHEETLONG-TENURED, HIGHLY EXPERIENCED MANAGEMENT TEAM TOP 15% property performance” in this Supplemental Information because we believe it promotes investors’ Three Months EndedNine Months Ended(In thousands)9/30/256/30/253/31/2512/31/249/30/249/30/259/30/24Basic shares for earnings per share170,181170,135170,522172,262172,058170,278172,007Unvested RSAs with forfeitable dividends - - - - - - - Diluted shares for earnings per share170,181170,135170,522172,262172,058170,278172,007Basic shares for funds from operations per share and funds from operations per share, as adjusted170,181170,135170,522172,262172,058170,278172,007Unvested RSAs with forfeitable dividends1245777 - - 73 - Diluted shares for funds from operations per share and funds from operations per share, as adjusted170,305170,192170,599172,262172,058170,351172,007Weighted-average unvested RSAs with nonforfeitable dividends used in calculating the allocations of net income, funds from operations, and funds from operations, as adjusted1,9171,9982,0532,4172,8381,9892,901 •A 1.0% reduction in projected 2025 same property net operating income and a 0.9% reduction in our projected operating occupancy percentage in North America as of December 31, 2025 (at the •During 1Q25 - 4Q26, we expect to deliver annual net operating income representing nearly cluster locations, including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland, Research Triangle, and New York City. As of September 30, 2025, Alexandria has a total market capitalization the joint venture agreement generally determines what equity holders can receive upon capital events, Represents the credit ratings assigned by S&P Global Ratings or Moody’s Ratings as of reflect the current operating performance with respect to related revenues or expenses. Our comprising gross unrealized gains and losses aggregating $180.4 million and •There are key lease expirations primarily located in the Greater Boston, San Francisco Bay Area, and San Diego markets aggregating 1.2 million RSF with a weighted-average lease consolidated statements of operations. Placed Into ServiceNear-Term DeliveriesYTD 3Q254Q25 - 4Q26$68M$111M94% Occupied80%Leased/Negotiating712,785 RSF969,524 RSF (3)The commercial paper program provides us with the ability to issue up to $2.5 billion of commercial paper notes that bear interest at short-term fixed rates and can generally be issued with a maturity of 30 days or less and with a decisions related to our real estate and non-real estate investments or other corporate activities that from strategic, corporate-level non-real estate investment decisions and external market conditions. technologies use; and (iii) 0.6% of other occupancy declines, primarily from space that became vacant during consolidated total income from rentals, as well as rental operating expenses in our operating results, can The 2018 White Paper published by the Nareit Board of Governors (the “Nareit White Paper”) Alexandria has a long-standing and proven track record of developing Class A/A+ concessions, if any, have elapsed and our total cash investment in the property. understanding of our operating results. We believe that the presentation of tenant recoveries is useful to midpoints of our guidance ranges), primarily due to slower than anticipated re-leasing of expiring spaces and lease-up of vacancy in our operating portfolio, reflecting reduced demand across the life of $27.8 billion and an asset base in North America that includes 39.1 million RSF of operating properties and 4.2 million RSF of Class A/A+ properties undergoing construction and one 100% pre-leased committed such as sales or refinancing, or in the event of a liquidation. Equity holders are normally entitled to their Market2025 Contractual Lease Expirations (in RSF)Annual Rental Revenue(per RSF)(1)2026 Contractual Lease Expirations (in RSF)Annual Rental Revenue(per RSF)(1)LeasedNegotiating/AnticipatingTargeted for Future Development/RedevelopmentRemainingExpiringLeasesTotal(2)LeasedNegotiating/AnticipatingTargeted for FutureDevelopment/RedevelopmentRemainingExpiring LeasesTotalGreater Boston21,892 - - 12,11334,005$57.84119,97811,897 - 229,566361,441$57.14San Francisco Bay Area - - - 55,76655,76664.7528,609103,596 - 282,976415,18169.31San Diego23,3271,579 - 48,79473,70062.02 - - 52,620(3)275,029327,64953.34Seattle50,552 - - 23,75674,30822.8034,719 - - 137,715172,43424.17Maryland1,136 - - 18,33819,47433.48 - 6,823 - 151,847158,67021.38Research Triangle10,4783,951 - 4,84319,272N/A22,660 - - 165,542188,20241.69New York City - 11,798 - 7,82519,623105.2212,168 - - 62,24174,40972.35Texas - - - - - - - - - - - - Canada - - - 40,67940,67910.72247,743 - - 1,755249,49821.72Non-cluster/other markets - - - - - - - - - 31,65931,65964.43Subtotal107,38517,328 - 212,114336,82744.52465,877122,31652,6201,338,3301,979,14348.10Key lease expirations(4) - - - 97,54497,54472.08 - - - 1,105,5081,105,50865.74Total107,38517,328 - 309,658434,371$50.71465,877122,31652,6202,443,8383,084,651$54.43Percentage of expiring leases25%4%0%71%100%15%4%2%79%100% September 30, 2025. A credit rating is not a recommendation to buy, sell, or hold securities and may be 8% growth in total net operating income from 2024 from projects that are 85% leased. impairments of real estate represent the write-down in the value of the assets to the estimated fair value maximum maturity of 397 days from the date of issuance. Borrowings under the program are used to fund short-term capital needs and are backed by our unsecured senior line of credit. In the event we are unable to issue $152.1 million, respectively. Dividend yield expiration date of March 19, 2026 and annual rental revenue aggregating $81 million, which are expected to become vacant upon lease expiration. We expect downtime on these may not be representative of the operating performance of our properties. Impairments of non-real estate investments and changes in the provision for expected credit losses on 3Q25 which we are currently marketing. These lease expirations resulting in the 1.1% decline in occupancy Public Biotechnology - Approved or Marketed show significant changes from period to period. In order to supplement an evaluation of our results of defines funds from operations as net income (computed in accordance with GAAP), excluding gains or investors as a supplemental measure of our ability to recover operating expenses under our triple net properties clustered in highly dynamic and collaborative Megacampus environments that science industry. commercial paper notes or refinance outstanding borrowings under terms equal to or more favorable than those under our unsecured senior line of credit, we expect to borrow under the unsecured senior line of credit at Unconsolidated real estate joint ventures’ debtAt 100%Unconsolidated Joint VentureMaturity DateStated RateInterest Rate(1)Aggregate CommitmentDebt Balance(2)Our Share101 West Dickman Street10/29/26SOFR+1.95%(3)6.20%$26,750$18,99958.4%1450 Research Boulevard12/6/26SOFR+1.95%(3)6.26%13,0008,93273.2%1655 and 1725 Third Street2/10/356.37%6.44%500,000496,79410.0%$539,750$524,725 near-term project expected to commence construction in the next year. Alexandria has a long-standing and proven track record of developing Class A/A+ properties clustered in highly dynamic and collaborative respective legal ownership of any residual cash from a joint venture only after all liabilities, priority Smaller redevelopments and repositioning of capital projects(1) - $1.1 billion S&P 500 Index TSR1,221% subject to revision or withdrawal at any time. Summary of occupancy less cost to sell. These impairments result from investing decisions or a deterioration in market •76% of the RSF in our total development and redevelopment pipeline is within our Capitalization rates A sector-leading REIT with a high-quality, diverse tenant base, strong margins, and long lease •Investment income of $28.2 million for 3Q25 presented in our consolidated statement of spaces ranging from 6 to 24 months on a weighted-average basis. Refer to “Contractual lease expirations” in the Supplemental Information for additional details. (1)Our guidance assumes an approximate 1% benefit related to a range of assets with vacancy that could potentially qualify for classification as held for sale in 4Q25 that have not yet reached the criteria for held for sale designation as of previously generated annual rental revenue aggregating approximately $29.0 million and had a weighted- financial instruments are not related to the operating performance of our real estate as they represent Other(1) BMOCantor FitzgeraldDeutsche Bank AGJefferiesJohn Kim / Juan SanabriaRichard AndersonTayo Okusanya / Samuel OhiomahJoe Dickstein / Katie Elders(212) 885-4115 / (312) 845-4074(929) 441-6927(212) 250-9284 / (212) 250-0057(212) 778-8771 / (917) 421-1968BNP Paribas ExaneCFRAEvercore ISIMizuho Securities USA LLCNate Crossett / Monir KoummalNathan SchmidtSteve Sakwa / James KammertVikram Malhotra(646) 342-1588 / (646) 342-1554(646) 517-1144(212) 446-9462 / (312) 705-4233(212) 282-3827BofA SecuritiesCitigroup Global Markets Inc.Green StreetRBC Capital MarketsFarrell Granath / Jeff SpectorNicholas Joseph / Seth BergeyDylan BurzinskiMichael Carroll(646) 855-1351 / (646) 855-1363(212) 816-1909 / (212) 816-2066(949) 640-8780(440) 715-2649BTIG, LLCCitizensJ.P. Morgan Securities LLCRobert W. Baird & Co. IncorporatedTom Catherwood / Michael TompkinsAaron Hecht / Linda FuAnthony Paolone / Ray ZhongWesley Golladay / Nicholas Thillman(212) 738-6140 / (212) 527-3566(415) 835-3963 / (415) 869-4411(212) 622-6682 / (212) 622-5411(216) 737-7510 / (414) 298-5053Fixed Income Research CoverageRating AgenciesBarclays Capital Inc.J.P. Morgan Securities LLCMoody’s Ratings S&P Global RatingsSrinjoy Banerjee / Ishaan PandyaMark Streeter / Tyler Schachner(212) 553-0376 Michael Souers(212) 526-3521 / (212) 526-2970(212) 834-5086 / (212) 834-2238 (212) 438-2508CreditSightsMizuho Securities USA LLCNicholas MogliaThierry Perrein(212) 340-3886(212) 205-7665 losses on sales of real estate, and impairments of real estate, plus depreciation and amortization of operations over a given quarterly or annual period, we analyze the operating performance for all •A reduction in projected 2025 realized gains on non-real estate investments. The midpoint of our revised guidance range for 2025 realized gains on non-real estate investments assumes leases, including recoveries of utilities, repairs and maintenance, insurance, property taxes, common Investment-grade or publicly traded large cap tenants SOFR+0.855%. As of September 30, 2025, we had $1.5 billion of commercial paper notes outstanding. enhance our tenants’ ability to successfully recruit and retain world-class talent and inspire Dividend yield for the quarter represents the annualized quarter dividend divided by the Megacampus environments that enhance our tenants’ ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to distributions, and claims have been repaid or satisfied. conditions. We also exclude realized and unrealized investment gain or loss, which results from Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsSeptember 30, 2025September 30, 2025Three Months EndedNine Months EndedThree Months EndedNine Months EndedTotal revenues$118,646$353,241$2,700$7,963Rental operations(38,170)(108,978)(1,025)(3,008)80,476244,2631,6754,955General and administrative(630)(2,193)(20)(101)Interest(151)(905)(1,060)(3,118)Depreciation and amortization of real estate assets(45,327)(114,785)(852)(2,848)Impairment of real estate - - - (8,673)Gain on sale of interest of unconsolidated JV - - 458458Fixed returns allocated to redeemable noncontrolling interests(1)541943 - - $34,909$127,323$201$(9,327)Straight-line rent and below-market lease revenue $6,663$16,857$172$506Funds from operations(2)$80,236$242,108$595$1,736 Operating PropertiesOperating and Redevelopment PropertiesMarket9/30/256/30/259/30/249/30/256/30/259/30/24Greater Boston86.8%(1)(2)90.1%94.6%73.6%76.7%80.9%San Francisco Bay Area90.4(1)(3)88.994.186.485.291.1San Diego95.294.896.095.294.896.0Seattle90.190.392.390.190.391.3Maryland93.993.996.293.993.996.2Research Triangle94.9(1)92.897.594.992.897.5New York City98.388.985.198.388.985.1Texas79.9(1)82.195.576.578.991.8Subtotal90.891.094.985.986.390.0Canada90.390.795.585.485.882.6Non-cluster/other markets69.672.672.869.672.672.8North America90.6%(1)(4)90.8%94.7%85.8%86.2%89.7% 3Q25. Megacampus ecosystems. average lease expiration date at the end of July 2025. terms operations consisted of $34.8 million of realized gains, $18.5 million of unrealized gains, and In addition, we believe that excluding charges related to stock compensation and unrealized 2024YTD 9/30/25 SUPPLEMENTAL the write-down of non-real estate investments when their fair values decrease below their respective operating real estate assets, and after adjustments for our share of consolidated and unconsolidated consolidated properties that were fully operating for the entirety of the comparative periods presented, (4)We calculate the weighted-average remaining term of our commercial paper notes by using the maturity date of our unsecured senior line of credit. Using the maturity date of our outstanding commercial paper notes, the approximately $15 million in 4Q25, compared to the quarterly average realized gains of approximately $32 million per quarter for the nine months ended September 30, 2025. area expenses, and other operating expenses, and of our ability to mitigate the effect to net income for Capitalization rates are calculated based on net operating income and net operating income closing common stock price at the end of the quarter. productivity, efficiency, creativity, and success. Development, redevelopment, and pre-construction •Capitalized interest - There is approximately $4.2 billion of average real estate basis capitalized during YTD 3Q25 related to future pipeline projects undergoing critical pre-construction transformative life science companies through our venture capital platform. We believe our unique business model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher (2)In October 2025, we executed a one-year lease extension aggregating 247,743 RSF with an investment-grade rated government institution tenant at a recently acquired office property in our Canada market. At acquisition, this building was (2)Represents temporary vacancies as of September 30, 2025 aggregating 617,458 RSF, primarily in the Greater investment decisions that occur at the corporate level related to non-real estate investments in publicly CREDIT RATING RANKING AMONG ALL PUBLICLY TRADED U.S. REITS(2) (1) Development and Redevelopment ProjectsIncremental Annual Net Operating IncomeRSFOccupied/Leased/NegotiatingPercentage(dollars in millions)Placed into service:1H25$52527,26896%3Q2516185,51789Placed into service in YTD 3Q25$68(1)712,78594%Expected to be placed into service:4Q25 through 4Q26$111(2)969,524(3)80%(4) gains or losses facilitates for investors a comparison of our business activities across periods without the $25.1 million of impairment charges. carrying values due to changes in general market or other conditions outside of our control. Significant partnerships and real estate joint ventures. Impairments represent the write-down of assets when fair Projected capital contributions from partners in consolidated real estate joint ventures to fund constructionTimingAmount(2)4Q25 through 2026$130,9802027 and beyond35,925Total$166,905 Investment-grade or publicly traded large cap tenants represent tenants that are investment- consolidated weighted-average maturity of our debt is 11.1 years. The commercial paper notes sold during the nine months ended September 30, 2025 were issued at a weighted-average yield to maturity of 4.64% and had a (As of September 30, 2025, unless stated otherwise)Occupancy of operating properties in North America90.6%Percentage of annual rental revenue in effect from Megacampus™ platform77%Percentage of annual rental revenue in effect from investment-grade or publicly traded large cap tenants53%Operating margin68%Adjusted EBITDA margin71%Percentage of leases containing annual rent escalations97%Weighted-average remaining lease term:Top 20 tenants9.4yearsAll tenants7.5yearsStrong 3Q25 tenant collections:3Q25 tenant rents and receivables collected as of October 27, 202599.9% We believe that this information can help investors estimate the balance sheet and operating referred to as same properties. We separately present quarterly and year-to-date same property results any significant variability to components of our operating expenses. (cash basis) annualized, excluding lease termination fees, on stabilized operating assets for the quarter originally targeted for a future change in use, but we instead renewed the existing tenant through the beginning of 2027, with no incremental capital investment. We continue to evaluate options to convert this space, subject to market Boston, San Francisco Bay Area, San Diego, and Seattle markets, that are leased and expected to be occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For more information on Alexandria, please visit www.are.com. 3)Our guidance range for net debt and preferred stock Adjusted EBITDA - 4Q25 annualized increased from less than or equal to 5.2x to a range of 5.5x to 6.0x. The primary drivers of the change include the activities, including various phases of entitlement, design, site work, and other activities necessary to begin aboveground vertical construction. We expect these projects to reach traded companies and certain privately held entities. Therefore, we do not consider these activities to be volatility resulting from market forces outside of our control. Adjusted EBITDA has limitations as a items, whether a gain or loss, included in the tabular disclosure for current periods are described in weighted-average maturity term of 17 days. value over the recoverability period is less than the carrying value due to changes in general market grade rated or publicly traded companies with an average daily market capitalization greater than $10 results information related to our partially owned entities. Presenting this information provides a to align with the interim financial information required by the SEC in our management’s discussion and A key component of our business model is our disciplined allocation of capital to the conditions. The impact from this renewal on our 2025 rental rate changes is anticipated to result in a reduction of approximately 2.0%. Weighted-average interest rate for capitalization of interest occupied upon completion of building and/or tenant improvements. The weighted-average expected delivery preceding the date on which the property is sold, or near-term prospective net operating income. following: Gross assets Space Intentionally Blank Alexandria also provides strategic capital to transformative life science an indication of operating performance of our real estate assets at the property level. Our calculation of anticipated pre-construction milestones on April 14, 2026, on a weighted-average real estate investment basis. We will evaluate, on an asset-by-asset basis, whether to (i) proceed with Advanced Technologies(2) ARE TSR1,064% measure of our performance. Adjusted EBITDA does not reflect our historical expenditures or future INFORMATION further detail in this Supplemental Information and accompanying Earnings Press Release. conditions and do not necessarily reflect the operating performance of the properties during the Other key highlights billion for the twelve months ended September 30, 2025, as reported by Bloomberg Professional perspective not immediately available from consolidated financial statements and one that can analysis of our financial condition and results of operations. These same properties are analyzed (3)The increase in the midpoint of our guidance range for 2025 interest expense is primarily due to the $450 million reduction to the midpoint of our guidance range for 2025 dispositions and sales of partial interests, which includes expected development and redevelopment of new Class A/A+ properties, as well as property enhancements date is approximately May 1, 2026 and the expected annual rental revenue is approximately $46 million. The following table reconciles income from rentals to tenant recoveries: net operating income also excludes charges incurred from changes in certain financing decisions, such Dividend strategy to share net cash flows from operating activities with stockholders while companies through our venture capital platform. We believe our unique business model Under construction - 2025 and 2026 stabilization - $650.0 million (80% leased/negotiating) additional pre-construction and/or construction activities based on leasing demand and/or market conditions, (ii) pause future investments, or (iii) consider the potential dispositions of •A $450 million reduction in the midpoint of our guidance range for 2025 dispositions and sales of partial interests. This includes expected delays in the closing of certain dispositions that are now 1450 Owens Street651 Gateway Boulevard269 East Grand Avenue701 Dexter Avenue NorthSan Francisco Bay Area/Mission BaySan Francisco Bay Area/South San FranciscoSan Francisco Bay Area/South San FranciscoSeattle/Lake Union212,796 RSF237,684 RSF107,250 RSF227,577 RSF requirements for capital expenditures or contractual commitments. While Adjusted EBITDA is a relevant Forward-Looking Statements corresponding period. The weighted-average interest rate required for calculating capitalization of interest pursuant delays in the closing of certain dispositions that are now anticipated to be completed in 1H26. Services. Credit ratings from Moody’s Ratings and S&P Global Ratings reflect credit ratings of the (1) (2) supplement an understanding of the joint venture assets, liabilities, revenues, and expenses included in separately from properties acquired subsequent to the first day in the earliest comparable quarterly or identified during the underwriting of certain acquired properties. These efforts are primarily concentrated Gross assets are calculated as total assets plus accumulated depreciation: Key items included in net income attributable to Alexandria’s common stockholders:YTD3Q253Q243Q253Q243Q253Q243Q253Q24(in millions, except per share amounts)AmountPer Share - DilutedAmountPer Share - DilutedUnrealized gains (losses) on non-real estate investments$18.5$2.6$0.11$0.02$(71.6)$(32.5)$(0.42)$(0.19)Gain on sales of real estate9.427.10.060.1622.527.50.130.16Impairment of non-real estate investments(25.1)(10.3)(0.15)(0.06)(75.5)(37.8)(0.45)(0.22)Impairment of real estate(1)(323.9)(5.7)(1.90)(0.03)(485.6)(36.5)(2.85)(0.22)Loss on early extinguishment of debt(0.1) - - - (0.1) - - - Increase in provision for expected credit losses on financial instruments - - - - (0.3) - - - Total$(321.2)$13.7$(1.88)$0.09$(610.6)$(79.3)$(3.59)$(0.47)(1)Refer to “Funds from operations and funds from operations per share” in the Earnings Press Release for additional details. Capitalized interest (1) as losses on early extinguishment of debt and changes in provision for expected credit losses on Average Debt OutstandingWeighted-Average Interest RateSeptember 30, 2025September 30, 2025Three Months EndedNine Months EndedThree Months EndedNine Months EndedLong-term fixed-rate debt$12,121,219$12,290,2033.88%3.86%Short-term variable-rate unsecured senior line of credit and commercial paper program debt1,503,453935,3534.644.64Blended-average interest rate13,624,67213,225,5563.963.92Loan fee amortization and annual facility fee related to unsecured senior line of creditN/AN/A0.140.13Total/weighted average$13,624,672$13,225,5564.10%4.05% retaining a significant portion for reinvestment Refer to “Megacampus” under “Definitions and reconciliations” in the Supplemental Information for additional details. anticipated to be completed in 1H26. and diligent underwriting ensure a high-quality and diverse tenant base that results in Key operating metrics these real estate assets. If we cease activities necessary to prepare a project for its intended use, costs related to such project, including interest, payroll, property taxes, insurance, and measure of performance, it does not represent net income (loss) or cash flows from operations Public/Private Mix (Cost)Tenant/Non-Tenant Mix (Cost) Megacampus™ VS Critical milestones in 4Q25 and 2026 - Future Megacampus projects(2) - $3.0 billion Three Months EndedNine Months Ended(In thousands)9/30/256/30/253/31/2512/31/249/30/249/30/259/30/24Income from rentals$735,849$737,279$743,175$763,249$775,744$2,216,303$2,286,457Rental revenues(541,070)(553,377)(552,112)(566,535)(579,569)(1,646,559)(1,737,804)Tenant recoveries$194,779$183,902$191,063$196,714$196,175$569,744$548,653 (4)Represents realized gains and losses included in funds from operations per share - diluted, as adjusted, and excludes significant impairments realized on non-real estate investments, if any. The midpoint of our revised guidance range for to GAAP represents a weighted-average rate as of the end of the applicable period, based on the rates tenant’s parent entity, and there can be no assurance that a tenant’s parent entity will satisfy the tenant’s our consolidated results. year-to-date period presented, properties that underwent development or redevelopment at any time in collaborative Megacampus™ ecosystems within AAA life science innovation clusters, as well as other (1)Includes projects with existing buildings that are generating or can generate operating cash flows. Also includes We compute funds from operations, as adjusted, as funds from operations calculated in This document includes “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. (In thousands)9/30/256/30/253/31/2512/31/249/30/24Total assets$37,375,148$37,623,629$37,600,428$37,527,449$38,488,128Accumulated depreciation6,416,7456,146,3785,886,5615,625,1795,624,642Gross assets$43,791,893$43,770,007$43,486,989$43,152,628$44,112,770 financial instruments, as these charges often relate to corporate strategy. Property operating expenses •A reduction in projected Adjusted EBITDA in 4Q25 related to the changes in same property performance (net operating income) and realized gains on non-real estate investments as described above. higher occupancy levels, longer lease terms, higher rental income, higher returns, and other costs directly related and essential to the construction of Class A/A+ properties, will be expensed as incurred. Refer to “Capitalization of interest” in the Supplemental Information for calculated and presented in accordance with GAAP, and it should not be considered as an alternative to 2025 realized gains on non-real estate investments assumes approximately $15 million in 4Q25, compared to the quarterly average realized gains of approximately $32 million per quarter for the nine months ended September 30, 2025. •Common stock dividend declared of $1.32 per share for 3Q25, aggregating $5.28 per Public Biotechnology - Preclinical or Clinical Stage applicable to borrowings outstanding during the period, including expense/income related to interest rate 230 Harriet Tubman Way10935, 10945, and 10955 Alexandria Way(2)10075 Barnes Canyon RoadSan Francisco Bay Area/South San FranciscoSan Diego/Torrey PinesSan Diego/Sorrento Mesa285,346 RSF334,996 RSF31,490 RSF100% Occupancy100% Occupancy100% Occupancy lease obligation upon such tenant’s default. We monitor the credit quality and related material changes during the comparative periods, unconsolidated real estate joint ventures, properties classified as held strategic locations that support innovation and growth. These projects are generally focused on development rights associated with existing operating campuses. Operating metrics3Q25YTD 3Q25(dollars in millions)Net operating income (cash basis) - annualized$1,928(1)$1,975(Decline)/Increase compared to 3Q24 and YTD 3Q24, annualized(5.8)%(2)1.3%(2)Same property performance:Net operating income changes(6.0)%(3.1)%Net operating income changes (cash basis) (3.1)%3.0%Occupancy - current-period average91.4%92.6%Occupancy - same-period prior-year average94.8%94.6% 10075 Barnes Canyon Road8800 Technology Forest PlaceSan Diego/Sorrento MesaTexas/Greater Houston221,589 RSF73,298 RSF68% Leased/Negotiating41% Leased/Negotiating We capitalize interest cost as a cost of a project during periods for which activities necessary (1)Total square footage includes 2,135,074 RSF of buildings currently in operation that we expect to demolish or redevelop and commence future construction subject to market conditions and leasing. Refer to “Investments in real estate” accordance with the Nareit White Paper, excluding significant gains, losses, and impairments realized Such forward-looking statements include, without limitation, statements regarding our projected 2025 earnings per share, projected 2025 funds from operations per share, projected 2025 funds from operations per included in determining net operating income primarily consist of costs that are related to our operating Refer to “Investments” in the Supplemental Information for additional details. those indicators in evaluating performance or liquidity. The components of balance sheet and operating results information related to our real estate greater long-term asset value. For more information on Alexandria, please visit additional details. A Megacampus ecosystem is a cluster campus that consists of approximately 1 million RSF or Refer to “Key assumptions” and “Key sources and uses of capital” on the following page. common share for the twelve months ended September 30, 2025, up 14 cents, or 2.7%, over hedge agreements, amortization of loan fees, amortization of debt premiums (discounts), and other bank of our tenants. Material changes that cause a tenant’s market capitalization to decrease below $10 for sale, and corporate entities (legal entities performing general and administrative functions), which are providing high-quality, generic, and reusable spaces that meet the real estate requirements of a wide Government Institutions under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties. to develop, redevelop, or reposition a project for its intended use are ongoing, provided that on non-real estate investments, unrealized gains or losses on non-real estate investments, impairments share, as adjusted, projected net operating income, and our projected sources and uses of capital. You can identify the forward-looking statements by their use of forward-looking words, such as “forecast,” properties, such as utilities, repairs, and maintenance; rental expense related to ground leases; joint ventures are limited as an analytical tool as the overall economic ownership interest does not As of 10/27/25As of 7/21/25 MidpointKey Changesto MidpointKey Sources and Uses of CapitalRangeMidpointCertain Completed ItemsSources of capital:Increase in debt$60$260$160See below$(290)$450 million increaseNet cash provided by operating activities after dividends425525475475Dispositions and sales of partial interests (refer to page 7) 1,1001,9001,500(1)1,950$450 million decreaseTotal sources of capital$1,585$2,685$2,135$2,135Uses of capital:Construction$1,450$2,050$1,750$1,750Acquisitions and other opportunistic uses of capital - 500250$208(2)250Ground lease prepayment135135135$135135Total uses of capital$1,585$2,685$2,135$2,135Increase in debt (included above):Issuance of unsecured senior notes payable$550$550$550$550$550Repayment of unsecured note payable(600)(600)(600)$(600)(600)Repayment of secured note payable(154)(154)(154)$(154)(3)(154)Unsecured senior line of credit, commercial paper, and other264464364(86)Increase in debt$60$260$160$(290)$450 million increase www.are.com. greater, including operating, active development/redevelopment, and land RSF less operating RSF fees. A separate calculation is performed to determine our weighted-average interest rate for Space Intentionally Blank the twelve months ended September 30, 2024. billion, which are not immediately reflected in the twelve-month average, may result in their exclusion excluded from same property results. Additionally, termination fees, if any, are excluded from the results BBB+Stable Projected 2025 Earnings per Share and Funds From Operations per Share Attributable to Alexandria’s Common Stockholders - DilutedAs of 10/27/25As of 7/21/25Key Changes to MidpointNet (loss) income per share(1)$(5.68) to $(0.20)$0.40 to $0.60(2)Depreciation and amortization of real estate assets7.057.05Gain on sales of real estate(0.14) to (1.54)(0.08)(2)Impairment of real estate - rental properties and land(3)6.69 to 2.670.77(2)Allocation to unvested restricted stock awards(0.03)(0.03)Funds from operations per share(4)$7.89 to $7.95$8.11 to $8.31Unrealized losses on non-real estate investments0.420.53Impairment of non-real estate investments(3)0.450.30Impairment of real estate0.230.23Allocation to unvested restricted stock awards(0.01)(0.01)Funds from operations per share, as adjusted(4)$8.98 to $9.04$9.16 to $9.36Midpoint$9.01$9.26Reduction of 25 cents(2) (2)Includes $3.7 billion of projects that are currently under construction and one 100% pre-leased committed near-term project expected to commence vertical construction in 2026. range of tenants. Upon completion, each development or redevelopment project is expected to generate (1)Includes interest expense and amortization of loan fees. expenditures for the asset have been made and interest cost has been incurred. Activities necessary to of real estate primarily consisting of right-of-use assets and pre-acquisition costs related to projects that •Realized gains on non-real estate investments - The midpoint of our revised guidance range for 2025 realized gains on non-real estate investments assumes approximately $15 million in “guidance,” “goals,” “projects,” “estimates,” “anticipates,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” “targets,” or “will,” or the negative of those words or similar words. These forward-looking contracted services, such as janitorial, engineering, and landscaping; property taxes and insurance; and In order to calculate the Adjusted EBITDA margin, we divide Adjusted EBITDA by total represent our legal claim to each of our joint ventures’ assets, liabilities, or results of operations. In expected to be demolished. The following table reconciles our annual rental revenue and development capitalization for each month. The rate will vary each month due to changes in variable interest rates, •Dividend yield of 6.3% as of September 30, 2025 and dividend payout ratio of 60% for the from this measure. of same properties. (2)Represents outstanding principal, net of unamortized deferred financing costs, as of September 30, 2025. increases in rental income, net operating income, and cash flows. Our development and redevelopment develop, redevelop, or reposition a project include pre-construction activities such as entitlements, we decided to no longer pursue, gains or losses on early extinguishment of debt, changes in the statements are based on our current expectations, beliefs, projections, future plans and strategies, anticipated events or trends, and similar expressions concerning matters that are not historical facts, as well as a property-level salaries. General and administrative expenses consist primarily of accounting and 4Q25, compared to the quarterly average realized gains of approximately $32 million per quarter for the nine months ended September 30, 2025. Refer to “Investments” in the We are not able to forecast the net income of future periods without unreasonable effort and revenues as presented in our consolidated statements of operations. We believe that this supplemental addition, joint venture financial information may include financial information related to the Projects under active construction with stabilization in 2025-2027 and beyond and one 100% pre-leased committed near-term project expected to commence in the next year - $3.7 billion and redevelopment pipeline RSF, excluding properties classified as held for sale, as of September 30, outstanding debt balances, the proportion of variable-rate debt to fixed-rate debt, the amount and terms Tenant base (3)This loan is subject to a fixed SOFR floor of 0.75%. three months ended September 30, 2025. projects are generally in locations that are highly desirable to high-quality entities, which we believe BiomedicalInstitutions(3) permitting, design, site work, and other activities preceding commencement of construction of provision for expected credit losses on financial instruments, significant termination fees, acceleration of number of assumptions concerning future events. There can be no assurance that actual results will not be materially higher or lower than these expectations. These statements are subject to risks, uncertainties, corporate compensation, corporate insurance, professional fees, rent, and supplies that are incurred as therefore do not provide a reconciliation for fixed-charge coverage ratio on a forward-looking basis. This Supplemental Information for additional details. performance measure provides investors with additional useful information regarding the profitability of unconsolidated real estate joint ventures that we do not control. We believe that in order to facilitate for Space Intentionally Blank 2025: Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. of interest rate hedge agreements, and the amount of loan fee and premium (discount) amortization. Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details. 13%Public Private Biotechnology 21%Tenant (3)
- Significant net cash flows provided by operating activities after dividends retained for results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater Space Intentionally Blank aboveground building improvements. The advancement of pre-construction efforts is focused on Alexandria is known for our high-quality and diverse tenant base, with 53% of our stock compensation expense due to the resignations of executive officers, deal costs, the income tax assumptions, and other important factors that could cause actual results to differ materially from the results discussed in the forward-looking statements. Factors that might cause such a difference include, without part of corporate office management. We calculate operating margin as net operating income divided by is due to the inherent difficulty of forecasting the timing and/or amount of items that depend on market our operating activities. investors a clear understanding of our operating results and our total assets and liabilities, joint venture Incremental annual net operating income on development and redevelopment projects (Dollars in thousands)Annual Rental RevenueDevelopment and Redevelopment Pipeline RSFMegacampus$1,522,94220,092,287Core and non-core452,5446,270,183Total$1,975,48626,362,470Megacampus as a percentage of annual rental revenue and of total development and redevelopment pipeline RSF77%76% 5.5x to 6.0x long-term asset value. reinvestment aggregating $2.3 billion for the years ended December 31, 2021 through 2024 •General and administrative expenses - Over the past several years, we have implemented comprehensive measures to reduce our expenditures across our organization, including our reducing the time required to deliver projects to prospective tenants. These critical activities add effect related to such items, and the amount of such items that is allocable to our unvested restricted annual rental revenue being generated from tenants that are investment-grade rated or Under construction and committed near-term project - stabilization in 2027 and beyond - $2.2 billion (28% leased/negotiating) 20%Non-Income-Producing Assets limitation, our failure to obtain capital (debt, construction financing, and/or equity) or refinance debt maturities, lower than expected yields, increased interest rates and operating costs, adverse economic or real total revenues. conditions outside of our control, including the timing of dispositions, capital events, and financing (1)Represents revenue-enhancing and non-revenue-enhancing capital expenditures before contributions from noncontrolling interests and tenant-funded and tenant-built landlord improvements for the year ending December 31, 2025. Our financial information should be examined in conjunction with our consolidated statements of operations Baa1Negative 40% to 60% Space Intentionally Blank Total equity capitalization and the midpoint of our 2025 guidance range. general and administrative expenses. These initiatives are expected to generate a reduction in general and administrative expenses of approximately $49 million, or 29%, during the year Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details on the square footage in service and under construction, if applicable. significant value for future ground-up development and are required for the vertical construction of stock awards. We compute the amount that is allocable to our unvested restricted stock awards with Incremental annual net operating income represents the amount of net operating income, on share of the 2025 revenue-enhancing and non-revenue-enhancing capital expenditures is projected to be $320 million at the midpoint of our guidance for 2025 construction spending. estate developments in our markets, our failure to successfully place into service and lease any properties undergoing development or redevelopment and our existing space held for future development or publicly traded large cap companies. The quality, diversity, breadth, and depth of our decisions, as well as quarterly components such as gain on sales of real estate, unrealized gains or We are not able to forecast the net income of future periods without unreasonable effort and and balance sheets. Joint venture financial information should not be considered an alternative to our Development projects generally consist of the ground-up development of generic and (1)Includes vacant square footage as of September 30, 2025. •In addition, as described in the “2026 Considerations” section of guidance, in light of market buildings. If we cease activities necessary to prepare a project for its intended use, interest costs related (1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 42,449 ALEXANDRIA’S MEGACAMPUS OCCUPANCY OUTPERFORMS THE MARKET(1) (4) 3.6x to 4.1x (2)Represents contractual capital commitments from existing real estate joint venture partners to fund construction. ending December 31, 2025 (at the midpoint of our 2025 guidance range) compared to the year ended December 31, 2024. Given that some of these costs savings are expected to be Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. nonforfeitable dividends using the two-class method. Under the two-class method, we allocate net an annual basis, expected to be realized upon a project being placed into service and achieving full redevelopment (including new properties acquired for that purpose), our failure to successfully operate or lease acquired properties, decreased rental rates, increased vacancy rates or failure to renew or replace We believe that in order to facilitate for investors a clear understanding of our operating (1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 42,449 RSF that were vacant and/or unleased at delivery. losses on non-real estate investments, impairments of real estate, impairments of non-real estate significant relationships with our tenants provide Alexandria with high-quality and stable (1)Refer to the table below for a summary of our previously disclosed key lease expirations that became vacant in 1Q25: We use Adjusted EBITDA as a supplemental performance measure of our operations, for Total equity capitalization is equal to the outstanding shares of common stock multiplied by the therefore do not provide a reconciliation for Adjusted EBITDA on a forward-looking basis. This is due to consolidated financial statements, which are presented and prepared in accordance with GAAP. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. reusable laboratory facilities. Redevelopment projects consist of the permanent change in use of RSF that were vacant and/or unleased at delivery. and life science industry conditions and our continued focus on capital efficiency, our Board of to such project are expensed as incurred. ALEXANDRIA’SMEGACAMPUS PLATFORM77%of Annual Rental Revenue 87%Private Future development projects(5) and land parcels, primarily located in Megacampuses with critical milestones in 4Q25 and 2026 - $4.9 billion 79%Non-Tenant (2)Represents the average delivery date for deliveries that occurred during the current quarter, weighted by annual rental revenue. income (after amounts attributable to noncontrolling interests) to common stockholders and to unvested temporary in nature, we anticipate approximately half of the cost reductions expected to be achieved in 2025 will continue in 2026. occupancy. Incremental annual net operating income is calculated as the initial stabilized yield multiplied PropertySubmarketVacant RSF as of 3Q25Vacant RSF leased as of 3Q25 with future delivery%Included in 3Q25 occupancy and same property results:Alexandria Technology Square® MegacampusCambridge182,05489,22249%507 East Howard Lane and 13813 Center Lake DriveAustin247,246102,93042429,300192,15245%Classified as held for sale as of 3Q25 (excluded from occupancy and same property results):409 Illinois StreetMission Bay234,249N/A7 Triangle DriveResearch Triangle104,531N/ATotal 1Q25 key lease expirations vacant at 3Q25768,080 expiring leases, defaults on or non-renewal of leases by tenants, adverse general and local economic conditions, an unfavorable capital market environment, decreased leasing activity or lease renewals, failure to results, net operating income should be examined in conjunction with net income or loss as presented in investments, and changes in provision for expected credit losses on financial instruments. Our attempt We are not able to forecast the net income of future periods without unreasonable effort and cash flows. Alexandria’s underwriting team and long-term industry relationships positively financial and operational decision-making, and as a supplemental means of evaluating period-to-period closing price on the last trading day at the end of each period presented. the inherent difficulty of forecasting the timing and/or amount of items that depend on market conditions Strong and flexible balance sheet with significant liquidity; top 15% credit rating ranking among all Net Operating IncomeNet Operating Income (Cash Basis)Percentage Change in Same Property Performance1Q252Q253Q251Q252Q253Q25As reported (3.1)%(5.4)%(6.0)%5.1%2.0%(3.1)%3Q25 same properties0.3%(2.5)%(6.0)%8.0%5.6%(3.1)% (2)Includes expected partial deliveries through 4Q26 from projects expected to stabilize in 2027 and beyond, (1)Represents a laboratory property with significant near-term lease expirations. acquired office, warehouse, or shell space into laboratory space. We generally will not commence new (3)Occupancy reflects total operating RSF placed in service as of each respective delivery date when the space was placed into service. Subsequent occupancy changes are not reflected. Directors expects to carefully evaluate our 2026 dividend strategy. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. restricted stock awards with nonforfeitable dividends by applying the respective weighted-average by the project’s total cost at completion. obtain LEED and other healthy building certifications and efficiencies, and other risks and uncertainties detailed in our filings with the Securities and Exchange Commission (“SEC”). Accordingly, you are cautioned our consolidated statements of operations. Net operating income should not be considered as an to predict these amounts may produce significant but inaccurate estimates, which would be potentially therefore do not provide a reconciliation for net debt and preferred stock to Adjusted EBITDA on a comparisons on a consistent basis. Adjusted EBITDA is calculated as earnings before interest, taxes, outside of our control, including the timing of dispositions, capital events, and financing decisions, as distinguish us from all other publicly traded REITs and real estate companies. Space Intentionally Blank 100% Pre-Leased Committed Near-Term Development (1)An observable price is a price observed in an orderly transaction for an identical or similar investment of the same Contractual lease expirations for properties classified as held for sale as of September 30, 2025 are excluded from the information on this page. including speculative future leasing that is not yet fully committed. Refer to the initial and stabilized occupancy publicly traded U.S. REITs (2)Dispositions completed during the three months ended September 30, 2025 had annual net operating income of $4.3 million (based on 2Q25 annualized) with a weighted-average disposition date of September 2, 2025. Additionally, •Dispositions and equity-type capital development projects for aboveground construction of new Class A/A+ laboratory space without first Critical milestones in 4Q25 and 2026 - Future Non-Megacampus projects - $1.2 billion Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details. Cash interest shares outstanding during each quarter-to-date and year-to-date period. This may result in a difference not to place undue reliance on such forward-looking statements. All forward-looking statements are made as of the date of this Earnings Press Release and Supplemental Information, and unless otherwise stated, alternative to net income or loss as an indication of our performance, nor as an alternative to cash flows misleading for our investors. forward-looking basis. This is due to the inherent difficulty of forecasting the timing and/or amount of depreciation, and amortization (“EBITDA”), excluding stock compensation expense, gains or losses on Total market capitalization issuer. Observable price changes result from, among other things, equity transactions for the same issuer with well as quarterly components such as gain on sales of real estate, unrealized gains or losses on non- Percentage of ARE’s Annual Rental Revenue Ongoing execution of Alexandria’s 2025 capital recycling strategy Net operating income is a non-GAAP financial measure calculated as net income (loss), the years under “New Class A/A+ development and redevelopment properties: current projects” in the October 2025 dispositions had annual net operating income of $13.0 million (based on 3Q25 annualized) with a weighted-average disposition date of October 13, 2025. (1)Includes our share of a gain on sale of real estate asset by an unconsolidated real estate joint venture of $458 thousand, which is classified as equity in earnings of unconsolidated real estate joint ventures in our consolidated securing significant pre-leasing for such space, except when there is solid market demand for high- •As of October 27, 2025, our share of pending dispositions subject to non-refundable deposits, signed letters of intent, and/or purchase and sale agreement negotiations aggregated WEIGHTED AVERAGE (1)Represents amounts in effect as of September 30, 2025. (1)Quarter annualized. •$27.8 billion in total market capitalization. of the summation of the quarter-to-date and year-to-date amounts. Neither funds from operations nor we assume no obligation to update this information and expressly disclaim any obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. For as a measure of our liquidity or our ability to make distributions. similar rights and obligations executed during the reporting period, including subsequent equity offerings or other items that depend on market conditions outside of our control, including the timing of dispositions, early extinguishment of debt, gains or losses on sales of real estate, impairments of real estate, changes real estate investments, impairments of real estate, impairments of non-real estate investments, and Supplemental Information for additional details. (3)Excludes a gain on sale of interest related to an unconsolidated real estate joint venture of $458 thousand, which is classified as equity in earnings of unconsolidated real estate joint ventures in our consolidated statement of operations. Executive and senior management team most directly comparable financial measure calculated and presented in accordance with GAAP, statements of operations. Cash interest is equal to interest expense calculated in accordance with GAAP plus (2)Excludes month-to-month leases aggregating 85,652 RSF as of September 30, 2025. We expect to fund a significant portion of our capital requirements for the year ending quality Class A/A+ properties. (2)Decrease in net operating income (cash basis) includes the impact of operating properties disposed of after $1.0 billion. We expect these dispositions to close in late 4Q25; therefore, the corresponding reduction in EBITDA is expected to impact 1Q26. Refer to “Dispositions and exchange of Total market capitalization is equal to the sum of total equity capitalization and total debt. reported equity transactions related to the same issuer. funds from operations, as adjusted, should be considered as alternatives to net income (determined in (1)In addition to the real estate joint ventures listed, we have one consolidated real estate joint venture in the Greater Boston market in which a partner holds a $48.7 million redeemable noncontrolling interest earning a fixed return. •$14.2 billion in total equity capitalization. more discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated in our forward-looking statements, and risks to our business in general, please refer to our (1) (3)Represents the RSF related to projects expected to stabilize by 4Q26. Does not include RSF for partial capital events, and financing decisions, as well as quarterly components such as gain on sales of real in provision for expected credit losses on financial instruments, and significant termination fees. Adjusted (4)Represents a retail shopping center with future development opportunity. We originally acquired the property in 2021 with the intent to demolish the retail center and develop it into laboratory space. However, due to the project’s financial changes in provision for expected credit losses on financial instruments. Our attempt to predict these (2)Primarily represents impairment charges to reduce the carrying amount of our investments in real estate assets to their respective estimated fair values less costs to sell upon their classification as held for sale in 3Q25, including (i) excluding equity in the earnings of our unconsolidated real estate joint ventures, general and (1) (3)Relates to a single-tenant, 100% pre-leased development project aggregating 466,598 RSF that expands the existing Campus Point by Alexandria Megacampus. At the beginning of 2026, the tenant will vacate 52,620 RSF, which capitalized interest, less amortization of loan fees and debt premiums (discounts). Refer to the definition January 1, 2024. Excluding these dispositions, net operating income (cash basis) - annualized for the three December 31, 2025 through dispositions of non-core assets, land, partial interest sales, and Refer to “Same property comparisons” under “Definitions and reconciliations” in the Supplemental Information for additional details, including a reconciliation of same properties to total properties. “Definitions and reconciliations” also (2)Represents a property currently under construction or in our future development and redevelopment pipeline. Refer to the sections under “New Class A/A+ development and redevelopment properties” in the Supplemental partial interests” in the Earnings Press Release for additional details. 91%Megacampus73%Market Alexandria’s executive and senior management team has unique experience and accordance with GAAP) as indications of financial performance, or to cash flows from operating deliveries through 4Q26 from projects expected to stabilize in 2027 and beyond. SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. We are not able to forecast the net income of future periods without unreasonable effort and $206.2 million related to our only property located in Long Island City, in our New York City market, which was a full building conversion to laboratory/office space and is currently 52% occupied, (ii) $43.4 million related to a retail •Net debt and preferred stock to Adjusted EBITDA of 6.1x and fixed-charge coverage ratio of outlook and the substantial capital that development would have required, we decided to recycle the capital generated by the disposition into our development and redevelopment pipeline. The capitalization rates of the disposition were estate, unrealized gains or losses on non-real estate investments, impairments of real estate, EBITDA also excludes unrealized gains or losses and significant realized gains or losses and amounts may produce significant but inaccurate estimates, which would be potentially misleading for our Percentage of Total Average Real Estate Basis Capitalized During YTD 3Q25 administrative expenses, interest expense, depreciation and amortization, impairments of real estate, generated annual rental revenue of $4.1 million as of 3Q25, from an existing building to allow for the demolition and development of the new, build-to-suit life science building at this site. Refer to “New Class A/A+ development and months ended September 30, 2025 would have decreased by 1.2%, and for the nine months ended contains definitions of “Tenant recoveries” and “Net operating income” and their respective reconciliations from the most directly comparable financial measures presented in accordance with GAAP. of fixed-charge coverage ratio for a reconciliation of interest expense, the most directly comparable Pre-construction activities include entitlements, permitting, design, site work, and other Information for additional details. Non-stabilized Properties sales to owner/users. We expect dispositions of land to represent 20% - 30% of our total Annual rental revenue and RSF include 100% of each property managed by us in North America. Refer to “Annual rental revenue” and “Investment-grade or publicly traded large cap tenants” under “Definitions and reconciliations” in the shopping center at 550 Arsenal Street that was originally intended to be a life science development in our Cambridge/Inner Suburbs submarket that was sold in October 2025, (iii) $31.8 million related to a vacant property that would (4)Represents the current leased/negotiating percentage of development and redevelopment projects that are •We expect construction spending in 2026 to be similar or slightly higher than the $1.75 billion midpoint of our guidance range for 2025 construction in order to complete our active 6.1% and 5.4% (cash basis) based upon net operating income and net operating income (cash basis), respectively, for 3Q25 annualized. activities (determined in accordance with GAAP) as measures of liquidity, nor are they indicative of the expertise in creating, owning, and operating highly dynamic and collaborative therefore do not provide a reconciliation for net operating income on a forward-looking basis. This is due 3.9x for 3Q25 annualized, with 4Q25 annualized targets of 5.5x to 6.0x and 3.6x to 4.1x, impairments of non-real estate investments, and changes in provision for expected credit losses on impairments that result from our non-real estate investments. These non-real estate investment amounts investors. 18%Occupancy Outperformance redevelopment properties: current projects” in the Supplemental Information for additional details. gains or losses on early extinguishment of debt, gains or losses on sales of real estate, and investment September 30, 2025 would have increased by 7.3%, compared to the corresponding periods in 2024. (3)Includes 409 and 499 Illinois, 1450, 1500, and 1700 Owens Street, and 455 Mission Bay Boulevard South. Operating RSF excludes 409 and 499 Illinois, which met the criteria to be designated as held for sale as of September financial measure calculated and presented in accordance with GAAP, to cash interest. require significant re-leasing capital in our Research Triangle submarket, and (iv) $27.8 million related to land parcels in our Sorrento Mesa submarket. 2019 - YTD 3Q25 DISPOSITIONS AND PARTIAL INTEREST SALES Total Shareholder ReturnFrom ARE’s IPO on May 27, 1997 to September 30, 2025 Supplemental Information for additional details, including our methodology of calculating annual rental revenue from unconsolidated real estate joint ventures and average market capitalization, respectively. activities preceding commencement of construction of aboveground building improvements. The expected to stabilize during 4Q25 through 4Q26. (5)In September 2025, we completed an exchange of partial interests in two consolidated joint ventures, Pacific Technology Park and 199 East Blaine Street, with one joint venture partner, resulting in a sales price received by cash of $1.6 Leasing activity includes 100% of results for properties in North America in which we have an investment. dispositions and sales of partial interests for 2025. availability of funds for our cash needs, including our ability to make distributions. construction projects and significant revenue- and non-revenue-enhancing capital expenditures necessary to lease vacant space. Given the factors previously described that could This document is not an offer to sell or a solicitation to buy securities of Alexandria Real Estate Equities, Inc. Any offers to sell or solicitations to buy our securities shall be made only by means of a to the inherent difficulty of forecasting the timing and/or amount of items that depend on market Megacampus real estate in key life science cluster locations to catalyze innovation. From financial instruments. Our attempt to predict these amounts may produce significant but inaccurate As of September 30, 2025. Annual rental revenue represents amounts in effect as of September 30, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details, including our methodology of calculating (4)Includes lease expirations at 20 properties primarily located in the Greater Boston, San Francisco Bay Area, and San Diego markets aggregating 1.2 million RSF with a weighted-average lease expiration date of March 19, 2026 and are classified in our consolidated statements of operations outside of total revenues. respectively. income or loss. We believe net operating income provides useful information to investors regarding our (1)Decrease in net operating income includes the impact of operating properties disposed of after January 1, 2024. Excluding these dispositions, net operating income for the three months ended September 30, 2025 would have 2025. (3)Calculated in accordance with standards established by the Nareit Board of Governors. million: advancement of pre-construction efforts is focused on reducing the time required to deliver projects to Refer to “Same property comparisons” under “Definitions and reconciliations” in the Supplemental Information for additional details, including a reconciliation of same properties to total properties. “Definitions and reconciliations” also (dollars in millions)Sales PriceTotal dispositions completed as of October 27, 2025$508Our share of pending transactions subject to non-refundable deposits, signed letters of intent, and/or purchase and sale agreement negotiations1,032Our share of completed and pending 2025 dispositions and sales of partial interests$1,540(1) prospectus approved for that purpose. Unless otherwise indicated, the “Company,” “Alexandria,” “ARE,” “we,” “us,” and “our” refer to Alexandria Real Estate Equities, Inc. and our consolidated subsidiaries. annual rental revenue from unconsolidated real estate joint ventures. conditions outside of our control, including the timing of dispositions, capital events, and financing annual rental revenue aggregating $81 million, which are expected to become vacant at lease expiration and re-leased to new tenants, including the following: negatively impact EBITDA, we may require significant equity-type capital to manage our leverage profile. design to development to the management of our high-quality, sustainable real estate, as estimates, which would be potentially misleading for our investors. •General and administrative expenses of $89.0 million for YTD 3Q25, representing cost (1)We expect to have limited borrowings, with less than $500.0 million outstanding on our unsecured senior line of credit and commercial paper program by the end of 2025. We expect to reduce the outstanding balance with •Significant liquidity of $4.2 billion, or 4.2x our debt maturities through 2027. Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details. (4)Primarily related to four non-real estate investments in privately held entities that do not report NAV. decreased by 3.7%, and for the nine months ended September 30, 2025 would have increased by 0.8%, compared to the corresponding periods in 2024. (4)Includes 10210, 10260, 10290, and 10300 Campus Point Drive and 4110, 4135, 4155, 4161, 4165, 4224, and 4242 Campus Point Court. financial condition and results of operations because it primarily reflects those income and expense (1)Excludes month-to-month leases aggregating 85,652 RSF and 136,131 RSF as of September 30, 2025 and December 31, 2024, respectively. During the trailing twelve months ended September 30, 2025, we granted free (1)Based on annual rental revenue in effect as of September 30, 2025. Net cash provided by operating activities after dividends GENERAL AND ADMINISTRATIVE EXPENSES AS A PERCENTAGE OF NET OPERATING INCOME(2) Non-Income-Producing Assets as a Percentage of Gross Assets
- We sold our 50% controlling interest in Pacific Technology Park, a non-Megacampus comprising five non-laboratory properties that were 93% occupied, at capitalization rates of 4.9% and 5.0% (cash basis). The disposition had prospective tenants. These critical activities add significant value for future ground-up development and contains definitions of “Tenant recoveries” and “Net operating income” and their respective reconciliations from the most directly comparable financial measures presented in accordance with GAAP. (1)Includes the real estate basis related to the 617,458 RSF of vacant space as of September 30, 2025 that is leased but not yet delivered. The weighted-average expected delivery date is approximately May 1, 2026. (i)Recently acquired properties comprising two properties aggregating 137,970 RSF in our Greater Stanford submarket for which we are evaluating options to reposition for advanced technologies use; Alexandria®, Lighthouse Design® logo, Building the Future of Life-Changing Innovation®, That’s What’s in Our DNA®, Megacampus™, At the Vanguard and Heart of the Life Science Ecosystem™, Alexandria decisions, as well as quarterly components such as gain on sales of real estate, unrealized gains or proceeds from our 2025 dispositions expected to close in 4Q25. Refer to “Dispositions and exchange of partial interests” in the Earnings Press Release for additional details. •We expect a significant source of funding to come from the sale of non-core assets in 2026. We anticipate an end to our large-scale non-core asset sales program in 2026 or early well as our ongoing cultivation of collaborative environments with unique amenities and reductions of $46.6 million or 34%, compared to YTD 3Q24, primarily the result of cost- (5)The noncontrolling interest share of our joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases from 55% to 75%, rent concessions averaging 1.2 months per annum. •Only 7% of our total debt matures through 2027. (2)Eikon Therapeutics, Inc. is a private biotechnology company led by renowned biopharmaceutical executive Roger Perlmutter, formerly an executive vice president at Merck & Co., Inc. As of February 25, 2025, the company has raised over items that are incurred at the property level. Therefore, we believe net operating income is a useful consolidated annual net operating income of $9.4 million based on 2Q25 annualized (at 100%). As of September 30, 2025, we no longer have any ownership interest in Pacific Technology Park, and the consolidated net operating 2025 DISPOSITIONS BY REAL ESTATE CLASSIFICATION(2) Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details, including its reconciliation from the most directly comparable financial measure presented in accordance with GAAP. (2)Includes four key projects on the following pages for additional details, which represent a total average capitalized real estate basis of approximately $1.2 billion during YTD 3Q25. (1)Image represents 60 Sylvan Road on the Alexandria Center® for Life Science - Waltham Megacampus. The project is expected to capture demand in our Route 128 submarket. are required for the vertical construction of buildings. Ultimately, these projects will provide high-quality (2)The decline in occupancy in 3Q25 was primarily due to one lease expiration of 78,380 RSF in Cambridge which we are marketing and a 72,846 RSF lease expiration located in Watertown which has been leased but was not (1)Represents the percentage of our annual rental revenue generated by professional services, finance, telecommunications, construction/real estate companies, and retail-related tenants. (ii)Two properties comprising 163,648 RSF in our University Town Center submarket and 118,225 RSF in our Torrey Pines submarket for which we are evaluating options to re-lease or reposition from single tenancy to multi-tenancy; (1)Reflects previously disclosed lease expirations aggregating 768,080 RSF that became vacant in 1Q25 as presented on page 25, “Summary of properties and occupancy” in the Supplemental Information. As of 3Q25, 338,780 RSF of (2)Refer to footnotes 2 through 4 on page 58 under “Fixed-rate and variable-rate debt” for additional details. Center®, Alexandria Technology Square®, Alexandria Technology Center®, and Alexandria Innovation Center® are copyrights and trademarks of Alexandria Real Estate Equities, Inc. All other company names, losses on non-real estate investments, impairments of real estate, impairments of non-real estate after which future capital would be contributed pro rata with our partner. Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details. Net cash provided by operating activities after dividends is reduced by distributions to (2)Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in the Supplemental Information for additional details, including total project costs. 2027. As of September 30, 2025, 77% of our annual rental revenue is from our Megacampus™ platform, and we expect this percentage to continue to grow over time. $1.2 billion in private venture capital funding. events, the Alexandria team has a best-in-class reputation of excellence in life science real control and efficiency initiatives related to reducing personnel-related costs and streamlining Key Credit Metrics TargetsAs of 10/27/25As of 7/21/25Key ChangesNet debt and preferred stock to Adjusted EBITDA - 4Q25 annualized 5.5x to 6.0xLess than or equal to 5.2x0.6x increase(2)Fixed-charge coverage ratio - 4Q25 annualized3.6x to 4.1x4.0x to 4.5x0.4x reduction income is no longer included in our statement of operations following the sale. measure for investors to evaluate the operating performance of our consolidated real estate assets. Net •11.6 years weighted-average remaining term of debt, longest among S&P 500 REITs. (1)Represents an allocation of joint venture earnings to redeemable noncontrolling interests for properties in the Greater Boston and San Francisco Bay Area markets. These redeemable noncontrolling interests earn a fixed return on (3)Includes future pipeline projects that are expected to reach anticipated pre-construction milestones, including various phases of entitlement, design, site work, and other activities necessary to begin aboveground vertical (2)68% of our annual rental revenue from advanced technologies tenants is from investment-grade or publicly traded large cap tenants. occupied as of September 30, 2025. (iii)One property aggregating 83,354 RSF in our Sorrento Mesa submarket, where the in-place credit tenant will relocate and expand into our development project at 10075 Barnes Canyon Road, which is expected to be delivered in facilities and are expected to generate significant revenue and cash flows. this vacant space met the criteria for classification as held for sale and has been excluded from our same property results. The remaining 429,300 RSF is included in our same property results for the three and nine months ended (6)Includes 9605, 9645, 9675, 9725, 9735, 9805, 9808, 9855, and 9868 Scranton Road and 10055, 10065, and 10075 Barnes Canyon Road. trademarks, and logos referenced herein are the property of their respective owners. investments, and changes in provision for expected credit losses on financial instruments. Our attempt (3)Includes the largest life science lease in company history, executed in July 2025 with a long-standing multinational pharmaceutical tenant. The 16-year expansion build-to-suit lease aggregates 466,598 RSF and is located (3)Includes leases, which are not subject to annual appropriations, with governmental entities such as the National Institutes of Health and the General Services Administration. Approximately 3% of the annual rental revenue derived from our noncontrolling interests and excludes changes in operating assets and liabilities as they represent timing •We acquired our partner’s 70% noncontrolling interest at 199 East Blaine Street, a fully occupied laboratory building located in our Alexandria Center® for Life Science - Eastlake Megacampus, with a weighted-average remaining lease (1)Represents the weighted-average interest rate as of the end of the applicable period, including amortization of loan fees, amortization of debt premiums (discounts), and other bank fees. their investment rather than participate in the operating results of the properties. estate. Alexandria’s highly experienced management team includes regional market business processes. Given that some of these cost savings are expected to be temporary in (1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 42,449 RSF that were vacant and/or unleased at delivery. operating income on a cash basis is net operating income adjusted to exclude the effect of straight-line construction on April 14, 2026 on a weighted-average real estate investment basis. We will evaluate whether to proceed with additional pre-construction and/or construction activities based on leasing demand and/or market (3)80% of our annual rental revenue from biomedical institutions is from investment-grade or publicly traded large cap tenants. (3)Increase in occupancy from 2Q25 is primarily due to the classification as held for sale of 409 and 499 Illinois Street on the Alexandria Center® for Science and Technology - Mission Bay Megacampus as of September 30, 2025, •Since 2021, our quarter-end fixed-rate debt has averaged 96.7%. 2H26; and (1)Consists of realized gains of $34.8 million and $94.7 million, partially offset by impairment charges of $25.1 million and $75.5 million during the three and nine months ended September 30, 2025, respectively. September 30, 2025. Excluding the impact of this vacant 429,300 RSF, same property net operating income changes for the three and nine months ended September 30, 2025 would have been (4.2)% and (1.3)% (cash basis), and (7)Includes 9965, 9975, 9985, and 9995 Summers Ridge Road.
- Dividends and net cash provided by operating activities after dividends (1)As of October 27, 2025, completed dispositions aggregated $508.3 million and our share of pending transactions subject to non-refundable deposits, signed letters of intent, or purchase and sale agreement negotiations aggregated (1)Represents a single-tenant project that expands the existing Campus Point by Alexandria Megacampus, where we currently have a 55% interest. Refer to “New Class A/A+ development and redevelopment properties: current at the Campus Point by Alexandria Megacampus in our University Town Center submarket. Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for leases with the United States Government is cancellable prior to the lease expiration date. to predict these amounts may produce significant but inaccurate estimates, which would be potentially term of 1.3 years. The purchase price exceeded the book value of the noncontrolling interest by $66.3 million, which was recognized in additional paid-in capital. As of September 30, 2025, we own 100% of 199 East Blaine Street. (2)Reflects any extension options that we control. differences. Refer to “Same property performance” and “Definitions and reconciliations” in the Supplemental Information for additional details. “Definitions and reconciliations” contains the definition of “Net operating income” and its reconciliation (2)Refer to “Funds from operations and funds from operations per share” in the Earnings Press Release and “Definitions and reconciliations” in the Supplemental Information for additional details. (2)Includes expected partial deliveries through 4Q26 from projects expected to stabilize in 2027 and beyond, including speculative future leasing that is not yet fully committed. Our share of incremental annual net operating income from conditions, pause future investments, or consider the potential disposition of real estate assets. WEIGHTED-AVERAGE REMAINING DEBT TERM (IN YEARS) partially offset by the new vacancy at 3301 Hillview Avenue, located in our Greater Stanford submarket, previously occupied by an acquired software tenant, for which we are evaluating options to reposition as an advanced directors with leading reputations and long-standing relationships within the life science rent, amortization of acquired above- and below-market lease revenue, amortization of deferred revenue nature, we anticipate approximately half of the cost reduction expected to be achieved in (iv)113,097 RSF at our Alexandria Center® at One Kendall Square Megacampus in our Cambridge submarket. We plan to upgrade most of these spaces, most of which have not undergone major improvements since our acquisition in (2)Consists of realized gains of $117.2 million, partially offset by impairment charges aggregating $58.1 million during the year ended December 31, 2024. •Total debt and preferred stock to gross assets of 31%. (1.9)% and 4.2% (cash basis), respectively. Development, redevelopment, and pre-construction spending also includes the following (8)In addition to the real estate joint ventures listed, we hold an interest in one insignificant unconsolidated real estate joint venture, $1.0 billion. We expect to achieve a weighted-average capitalization rate on our projected 2025 dispositions and sales of partial interests (excluding land and including stabilized and non-stabilized operating properties) in the 7.5% - 8.5% projects” in the Supplemental Information for additional details. additional details. (4)Includes (i) ground leases for land at 1455 and 1515 Third Street (two buildings aggregating 422,980 RSF) and (ii) leases at 1655 and 1725 Third Street (two buildings aggregating 586,208 RSF) in our Mission Bay submarket owned by (1)Source: U.S. House Committee on Energy and Commerce, “The 21st Century Cures Discussion Document White Paper,” January 27, 2015. •From 2013 to 2025, dividends per share and funds from operations per share, as adjusted have been highly correlated, with cumulative increases of 102% and 105%, respectively. (3)Refer to footnotes 2 through 4 under “Fixed-rate and variable-rate debt” in “Summary of debt” for additional details. from the most directly comparable financial measure presented in accordance with GAAP. misleading for our investors. (4)In addition to capitalized interest, we incur additional capitalized project costs, including property taxes, insurance, and other costs directly related and essential to the construction of Class A/A+ properties. If we cease activities development and redevelopment projects expected to be placed into service primarily commencing from 4Q25 through 4Q26 is projected to be $83 million. Refer to the initial and stabilized occupancy years under “New Class A/A+ technologies campus. 2016. (3)Consists of unrealized gains of $51.3 million primarily resulting from the increase in fair values of our investments in publicly traded entities and investments in privately held entities that report NAV and $32.8 million resulting from related to tenant-funded and tenant-built landlord improvements, and changes in the provision for Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. communities in their respective innovation clusters. We believe that our experience, (2)Includes the impact of initial free rent concessions that burned off after January 1, 2024 for development and redevelopment projects that were placed into service in 2023 and accordingly are part of our same property pool for the (1)Image represents 500 North Beacon Street on The Arsenal on the Charles Megacampus. 2025 will continue in 2026.
- $166.9 million of capital contribution commitments from existing real estate joint venture As of September 30, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (9)Represents a joint venture with a local real estate operator in which our joint venture partner manages the day-to-day activities that significantly affect the economic performance of the joint venture. range. We expect dispositions of land to represent 20% - 30% of our total dispositions and sales of partial interest sales for the year ending December 31, 2025. Refer to “Dispositions and exchange of partial interests” in the Earnings Press (2)Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including future development and redevelopment square feet currently included in rental properties. (4)Includes 75,735 of vacant RSF at one recently acquired asset in our Greater Stanford submarket for which we are evaluating options to reposition for advanced technologies use. our unconsolidated real estate joint venture in which we have an ownership interest of 10%. Annual rental revenue is presented using 100% of the annual rental revenue from our consolidated properties and our share of annual rental costs: (i) amounts to bring certain acquired properties up to market standard and/or other costs identified (2)Source: PhRMA, “Medicines in Development for Chronic Diseases: 2024 Report.” necessary to prepare a project for its intended use, costs related to such project are expensed as incurred. Annualized capitalized operating expenses and payroll represent approximately 2% and 1%, respectively, of the total (4)Includes temporary vacancies as of September 30, 2025 aggregating 617,458 RSF, or 1.6% of total operating RSF, primarily in the Greater Boston, San Francisco Bay Area, San Diego, and Seattle markets, which are leased development and redevelopment properties: current projects” in the Supplemental Information for additional details.
- The factors previously described could lead to a reduction in funds from operations per share, as adjusted and net cash provided by operating activities. At the current dividend rate, (1)Excludes an exchange of partial interests of Pacific Technology Park and 199 East Blaine Street with nominal accounting reclassifications of unrealized gains recognized in prior periods into realized gains upon our realization of investments during the three months ended September 30, 2025. nine months ended September 30, 2025, including at 325 Binney Street in our Cambridge submarket, 15 Necco Street in our Seaport Innovation District submarket, and 751 Gateway Boulevard in our South San Francisco submarket. (2)Image represents 10955 Alexandria Way on the One Alexandria Square Megacampus. expected credit losses on financial instruments required by GAAP. We believe that net operating income (1)Represents the average quarterly percentage fixed-rate debt as of each quarter-end from January 1, 2021 through September 30, 2025. expertise, reputation, and key relationships in the real estate and life science industries We continue to evaluate the business plans and re-leasing strategies for these projects to maximize occupancy and rental revenue. We expect downtime on the 1.2 million RSF to range from 6 to 24 months on a weighted-average basis, •As a percentage of net operating income, our general and administrative expenses for the Release for additional details. (3)Balances exclude accumulated depreciation and our share of the cost basis associated with our properties held by our unconsolidated real estate joint ventures, which is classified as investments in unconsolidated real estate joint revenue from our unconsolidated real estate joint ventures. Excluding these ground leases, the weighted-average remaining lease term for our top 20 tenants was 7.7 years as of September 30, 2025. (3)Source: Centers for Disease Control and Prevention, “Heart Disease Facts,” October 24, 2024. Represents the latest published data, which reflects the U.S. estimate for 2022. partners to fund construction from 4Q25 through 2027 and beyond. (1)Excludes unrealized gains or losses on non-real estate investments after September 30, 2025 that are required to be recognized in earnings and are excluded from funds from operations per share, as adjusted. during the acquisition process (generally within two years of acquisition) and (ii) permanent conversion average real estate basis subject to capitalization for YTD 3Q25. (1)Refer to footnote 1 under “Same property performance” in the Supplemental Information for additional details. (1)Refer to page 2 in the Earnings Press Release and “Summary of properties and occupancy” in the Supplemental Information for additional details. and expected to be occupied upon completion of building and/or tenant improvements. The weighted-average expected delivery date is approximately May 1, 2026 and the expected annual rental revenue is approximately $46 Source: S&P Global Market Intelligence. (3)Represents the current leased/negotiating percentage of development and redevelopment projects that are expected to stabilize during 4Q25 through 4Q26. net cash proceeds. Refer to “Dispositions and exchange of partial interests” in the Earnings Press Release for Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details. Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details. Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details. Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details. Source: U.S. Food and Drug Administration. Novel therapies approved by the FDA (Center for Drug Evaluation and Research) include new molecular entities and new biologics defined as products containing active moieties that have the amount of net cash provided by operating activities after payment of dividends available to recycle and address our 2026 capital needs could be reduced. As a result, we expect Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (4)Primarily relates to the accounting reclassifications of unrealized gains recognized in prior periods into realized gains upon our realization of investments during the nine months ended September 30, 2025. Excluding the impact of these initial free rent concessions, same property net operating income changes (cash basis) for the nine months ended September 30, 2025 would have been (0.3)%. As of September 30, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (1) Refer to footnote 2 in “Funds from operations and funds from operations per share” in the Earnings Press Release for additional details. (2)Top 15% ranking represents credit rating levels from S&P Global Ratings and Moody’s Ratings for publicly traded U.S. REITs, from Bloomberg Professional Services and Nareit, as of September 30, 2025. on a cash basis is helpful to investors as an additional measure of operating performance because it and we expect these properties to remain operating properties. (2)Under our common stock repurchase program authorized in December 2024, we may repurchase up to $500 million of our common stock through December 31, 2025. During 3Q25, we did not repurchase any shares of common stock. As ventures in our consolidated balance sheet. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details. (5)Represents one lease encompassing four properties acquired in 2022 that we expect to reposition upon lease expiration. This lease with Cloud Software Group, Inc. (formerly known as TIBCO Software, Inc.) was in place when we (4)Source: National Cancer Institute, “Cancer Statistics,” updated May 7, 2025. Represents the latest published data, which reflects 2018 - 2021 data, not including 2020 due to COVID. (2)Refer to the discussion regarding key changes to our 2025 guidance above for additional details. provide Alexandria significant competitive advantages in attracting new business Source for S&P 500 REIT data: S&P Global Market Intelligence. (2)Refer to “Same property performance” in the Supplemental Information for additional details. trailing twelve months ended September 30, 2025 were 5.7% - the lowest level in the past million. (2)For the three months ended September 30, 2025. of space for highly flexible, move-in-ready laboratory space to foster the growth of promising early- and (4)Represents the RSF related to projects expected to stabilize by 4Q26. Does not include RSF for partial deliveries through 4Q26 from projects expected to stabilize in 2027 and beyond. (1)Represents aggregate proceeds from outright sales and sales of partial interests. additional details. not previously been approved by the FDA. (1)Quarter annualized. (5)Primarily relates to the accounting reclassifications of unrealized gains recognized in prior periods into realized gains upon our realization of investments during the year ended December 31, 2024. (1)Represents annual net operating income for the quarter preceding the date on which the property is sold, or near-term prospective net operating income. our Board of Directors to carefully evaluate our 2026 dividend strategy. (1)Represents the occupancy of operating properties at Alexandria’s Megacampus ecosystems within the Greater Boston, San Francisco Bay Area, and San Diego markets as of September 30, 2025, compared to the average market (3)Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for PSA and WY) as of June 30, 2025, except for ARE, which is as of September 30, 2025. of October 27, 2025, the approximate value of shares authorized and remaining under this program was $241.8 million. Subject to market conditions, we may consider repurchasing additional shares of our common stock. (4)Our share of investment in our development and redevelopment pipeline is $7.6 billion. (3)Refer to “Funds from operations and funds from operations per share” in the Earnings Press Release for additional details. acquired the properties, of which 137,970 RSF has lease expirations through 2026. Refer to footnote 3 in “Contractual lease expirations” in the Supplemental Information for additional details. eliminates straight-line rent revenue and the amortization of acquired above- and below-market leases (5)Source: Alzheimer’s Association, “2025 Alzheimer’s Disease Facts and Figures.” Represents the latest published data, which reflects the U.S. estimate for 2025. (1)Trailing twelve months ended September 30, 2025 and June 30, 2025, respectively. Refer to “2026 Considerations” in the Earnings Release for additional details. (3)Percentages calculated based on our annual rental revenue in effect as of September 30, 2025. opportunities. (2)Total gains and impairments include any amounts related to sales of partial interests recognized in additional paid-in capital. ten years and approximately half the average of other S&P 500 REITs. Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future growth-stage life science companies. (1)Includes two additional approvals through October 24, 2025. (6)Represents 2.7% of gross assets as of September 30, 2025. Refer to “Gross assets” under “Definitions and reconciliations” in the Supplemental Information for additional details. (2)Represents completed and pending YTD 2025 dispositions.. Refer to “Dispositions and Exchange of Partial Interests” in the Earnings Release for additional details. occupancy for these markets per the Q2 2025 U.S. Life Sciences Report published by CBRE Research. As of September 30, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (1)Source: U.S. House Committee on Energy and Commerce, “The 21st Century Cures Discussion Document White Paper,” January 27, 2015. Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for PSA and WY) as of June 30, 2025, except for ARE, which is as of September 30, 2025 (4)Refer to “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” under “Definitions and reconciliations” in the Supplemental Information for additional details. (3)In August 2025, we repaid a secured construction loan held by our development project at 99 Coolidge Avenue in our Cambridge/Inner Suburbs submarket. Refer to “Key capital events” in the Earnings Press Release for additional details. (5)As of September 30, 2025, annual rental revenue from future development parcels with existing income was approximately 1% of total annual rental revenue. (2)Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details. and tenant-funded and tenant-built landlord improvements. (4)Represents the weighted-average remaining term based on annual rental revenue in effect as of September 30, 2025. development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing properties subject to market conditions and leasing. development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing properties subject to market conditions and leasing. development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing properties subject to market conditions and leasing. development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing properties subject to market conditions and leasing. Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025 Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025 Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025 Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025iii Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025iv Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025v Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025vi Alexandria Real Estate Equities, Inc. All Rights Reserved. © 2025vii Alexandria Real Estate Equities, Inc. 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