Open the filing on EDGARTable of ContentsDecember 31, 2025 Fourth Quarter and Year Ended December 31, 2025 Financial and Operating Results (continued) December 31, 2025 Fourth Quarter and Year Ended December 31, 2025 Financial and Operating Results (continued) December 31, 2025 GuidanceDecember 31, 2025(Dollars in millions, except per share amounts) Guidance (continued)December 31, 2025 2025 Dispositions and Sales of Partial InterestsDecember 31, 2025(Dollars in thousands) Earnings Call Information and About the CompanyDecember 31, 2025 Consolidated Statements of OperationsDecember 31, 2025(Dollars in thousands, except per share amounts) Consolidated Balance SheetsDecember 31, 2025(In thousands) Funds From Operations and Funds From Operations per ShareDecember 31, 2025(In thousands) Funds From Operations and Funds From Operations per Share (continued)December 31, 2025(In thousands, except per share amounts) Company ProfileDecember 31, 2025 Investor InformationDecember 31, 2025 Financial and Asset Base HighlightsDecember 31, 2025(Dollars in thousands, except per share amounts) Financial and Asset Base Highlights (continued)December 31, 2025(Dollars in thousands, except annual rental revenue per occupied RSF amounts) High-Quality and Diverse Client BaseDecember 31, 2025 Key Operating MetricsDecember 31, 2025 Same Property PerformanceDecember 31, 2025(Dollars in thousands) Leasing ActivityDecember 31, 2025(Dollars per RSF) Leasing Activity - Tenant MixDecember 31, 2025 Contractual Lease ExpirationsDecember 31, 2025 Top 20 TenantsDecember 31, 2025(Dollars in thousands, except average market cap amounts) Summary of Properties and OccupancyDecember 31, 2025(Dollars in thousands, except per RSF amounts) Property ListingDecember 31, 2025(Dollars in thousands) Property Listing (continued)December 31, 2025(Dollars in thousands) Property Listing (continued)December 31, 2025(Dollars in thousands) Property Listing (continued)December 31, 2025(Dollars in thousands) Property Listing (continued)December 31, 2025(Dollars in thousands) Property Listing (continued)December 31, 2025(Dollars in thousands) Investments in Real EstateDecember 31, 2025 Investments in Real EstateDecember 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Recent DeliveriesDecember 31, 2025 New Class A/A+ Development and Redevelopment Properties: Recent DeliveriesDecember 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Current Projects December 31, 2025 New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)December 31, 2025 New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)December 31, 2025 New Class A/A+ Development and Redevelopment Properties: Current Projects (continued)December 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of PipelineDecember 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)December 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)December 31, 2025(Dollars in thousands) New Class A/A+ Development and Redevelopment Properties: Summary of Pipeline (continued)December 31, 2025(Dollars in thousands) Construction SpendingDecember 31, 2025(Dollars in thousands) Capitalization of InterestDecember 31, 2025(Dollars in thousands) Joint Venture Financial InformationDecember 31, 2025 Joint Venture Financial Information (continued)December 31, 2025(In thousands) InvestmentsDecember 31, 2025(Dollars in thousands) Balance SheetDecember 31, 2025 Key Credit MetricsDecember 31, 2025 Summary of DebtDecember 31, 2025(Dollars in millions) Summary of Debt (continued)December 31, 2025 Summary of Debt (continued)December 31, 2025(Dollars in thousands) Summary of Debt (continued)December 31, 2025(Dollars in thousands) Summary of Debt (continued)December 31, 2025(Dollars in thousands) Definitions and ReconciliationsDecember 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Definitions and Reconciliations (continued)December 31, 2025 Alexandria’s Long-Standing Track Record of Monetizing EmbeddedAsset Value: 2019 - 2025 Dispositions and Partial Interest Sales
2025 Dispositions and Sales of Partial Interests Update Alexandria’s Key Disposition In 4Q25 - 409 and 499 Illinois Street in Mission Bay ALEXANDRIA CONTINUES TO HAVE A STRONG AND FLEXIBLE BALANCE SHEET WITH SIGNIFICANT LIQUIDITY Alexandria Executes Lease Through 2041 With High-Credit Tenant AstraZeneca for 171,239 RSF Mission-Critical Manufacturing Facility in Maryland
ALEXANDRIA’SPATH FORWARD CONTINUE TO SUCCESSFULLY MANAGE AND REDUCE G&AAlexandria’s General and Administrative Expense Levels Outperform Other S&P 500 REITs Based on our current view of existing market conditions and assumptions for the year ending December 31, 2026, our guidance for 2026 that was initially provided on December 3, 2025 has been ALEXANDRIA: THE MOST TRUSTED BRAND IN LIFE SCIENCE REAL ESTATE™ WE INVENTED IT.WE DOMINATE IT. Interest SoldSquare FootageCapitalization RateCapitalization Rate(Cash Basis)Price(Our Share)Gain on Sales of Real EstatePropertySubmarket/MarketDate of TransactionOperatingFuture Development Completed in YTD 3Q25, excluding exchange of partial interests (see below)$340,871$13,241(1)Completed in 4Q25:Stabilized properties:550 Arsenal Street(2)Cambridge/Inner Suburbs/Greater Boston10/15/25100%249,275281,5926.1%5.4%99,250 - 6260 Sequence DriveSorrento Mesa/San Diego12/16/25100%130,536 - 7.2%7.1%70,000 - 5600 Avenida EncinasOther/San Diego12/17/25100%182,276 - 5.5%5.3%64,100 - 601 Keystone Park DriveResearch Triangle/Research Triangle10/3/25100%77,595 - 9.7%8.7%24,8794,362Other stabilized propertiesVarious307,142 - 103,079 - 361,308Properties with vacancy or significant near-term capital requirements:601, 611, 651, 681, 685, 701, and 751 Gateway BoulevardSouth San Francisco/San Francisco Bay Area12/30/25(3)1,104,826528,684N/A283,173(3) - (3)ARE NautilusTorrey Pines/San Diego12/10/25100%218,640 - 192,000(4)86,260409 and 499 Illinois StreetMission Bay/San Francisco Bay Area12/17/2525%466,297 - 180,273(5)416,749(5)14 TW Alexander DriveResearch Triangle/Research Triangle11/20/25100%173,820 - 155,000(6)78,4894767 Nexus Center DriveUniversity Town Center/San Diego12/31/25100%65,280 - 50,000(7)15,330Alexandria Center for Life Science - Long Island CityNew York City/New York City12/19/25100%179,100 - 34,500 - Other non-stabilized propertiesVarious469,992117,22797,183746992,129Land:9363, 9373, and 9393 Towne Centre DriveUniversity Town Center/San Diego12/18/25100% - 230,000N/A40,00017,978285, 299, 307, and 345 Dorchester AvenueSeaport Innovation District/Greater Boston12/30/2560% - 1,040,00033,500 - 3029 East Cornwallis RoadResearch Triangle/Research Triangle12/31/25100% - 600,00029,500 - Other land parcelsVarious - 211,23214,900 - 117,900Total dispositions completed in 4Q251,471,337(8)619,914Total completed 2025 dispositions and sales of partial interests, excluding exchange of partial interests (see below)$1,812,208$633,155Exchange of partial interestsDisposition of Pacific Technology ParkSorrento Mesa/San Diego9/9/2550%544,352 - N/A$96,000$9,290Acquisition of 199 East Blaine StreetLake Union/Seattle9/9/2570%115,084 - (94,430)Difference in sales price received in cash$1,570 The following table presents a reconciliation of net income (loss) attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in accordance Three Months Ended (unless stated otherwise)12/31/259/30/256/30/253/31/2512/31/24Selected financial data from consolidated financial statements and related informationRental revenues$538,330$541,070$553,377$552,112$566,535Tenant recoveries$190,542$194,779$183,902$191,063$196,714General and administrative expenses$28,020$29,224$29,128$30,675$32,730General and administrative expenses as a percentage of net operating income - trailing 12 months5.6%5.7%6.3%6.9%7.6%Operating margin69%68%71%70%70%Adjusted EBITDA margin70%71%71%71%72%Adjusted EBITDA - quarter annualized$2,097,444$2,130,008$2,174,160$2,165,632$2,273,480Adjusted EBITDA - trailing 12 months$2,141,811$2,185,820$2,208,226$2,218,722$2,228,921Net debt at end of period $11,921,114$13,085,745$12,844,726$12,687,856$11,762,176Net debt and preferred stock to Adjusted EBITDA - quarter annualized5.7x6.1x5.9x5.9x5.2xNet debt and preferred stock to Adjusted EBITDA - trailing 12 months5.6x6.0x5.8x5.7x5.3xTotal debt and preferred stock at end of period$12,400,555$13,593,541$13,294,100$13,090,834$12,244,374Gross assets at end of period$40,209,360$43,791,893$43,770,007$43,486,989$43,152,628Total debt and preferred stock to gross assets at end of period31%31%30%30%28%Fixed-charge coverage ratio - quarter annualized3.7x3.9x4.1x4.3x4.3xFixed-charge coverage ratio - trailing 12 months4.0x4.1x4.3x4.4x4.5xUnencumbered net operating income as a percentage of total net operating income100.0%100.0%99.7%99.8%99.9%Closing stock price at end of period$48.94$83.34$72.63$92.51$97.55Common shares outstanding (in thousands) at end of period 170,538170,339170,146170,130172,203Total equity capitalization at end of period$8,346,123$14,196,059$12,357,709$15,738,715$16,798,446Total market capitalization at end of period$20,746,678$27,789,600$25,651,809$28,829,549$29,042,820Dividend per share - quarter/annualized$0.72/$2.88$1.32/$5.28$1.32/$5.28$1.32/$5.28$1.32/$5.28Dividend payout ratio for the quarter33%60%57%57%55%Dividend yield - annualized5.9%6.3%7.3%5.7%5.4%Amounts related to operating leases:Operating lease liabilities at end of period$360,543$361,986$363,419$371,412$507,127Rent expense$8,566$10,645$12,139$11,666$10,685Capitalized interest$81,845$86,091$82,423$80,065$81,586Average real estate basis capitalized during the period$8,046,984$8,407,332$8,107,180$8,026,566$8,118,010Weighted-average interest rate for capitalization of interest during the period4.07%4.10%4.07%3.99%4.02%Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. Three Months Ended (unless stated otherwise)12/31/259/30/256/30/253/31/2512/31/24Amounts included in funds from operations and non-revenue-enhancing capital expendituresStraight-line rent revenue$14,096$18,821$18,536$22,023$17,653Amortization of acquired below-market leases$5,889$6,456$10,196$15,222$15,512Amortization of deferred revenue related to tenant-funded and -built landlord improvements$5,264$5,455$2,401$1,651$1,214Straight-line rent expense on ground leases$116$114$87$149$1,021Cash payment for ground lease extension$ - $ - $ - $(135,000)$(135,000)Stock compensation expense$8,232$10,293$12,530$10,064$12,477Amortization of loan fees $4,481$4,505$4,615$4,691$4,620Amortization of debt discounts$327$325$335$349$333Non-revenue-enhancing capital expenditures:Building improvements $4,372$3,948$4,622$3,789$4,313Tenant improvements and leasing commissions$26,494$16,707$23,971$73,483$81,918Funds from operations attributable to noncontrolling interests$77,922$80,236$80,860$81,012$76,111Operating statistics and related information (at end of period)Number of properties - North America340375384386391RSF - North America (including development and redevelopment projects under construction)39,449,37242,887,96443,699,92243,687,34344,124,001Total square footage - North America59,382,07966,417,02667,220,33768,518,18469,289,411Annual rental revenue per occupied RSF - North America$59.97$58.94$58.68$58.38$56.98Occupancy of operating properties - North America90.9%(1)90.6%90.8%91.7%94.6%Occupancy of operating and redevelopment properties - North America86.9%85.8%86.2%86.9%89.7%Weighted-average remaining lease term (in years) 7.57.57.47.67.5Total leasing activity - RSF1,220,9441,171,344769,8151,030,5531,310,999Lease renewals and re-leasing of space - change in new rental rates over expiring rates:Rental rate changes(9.9)%15.2%5.5%18.5%18.1%Rental rate changes (cash basis)(5.2)%6.1%6.1%7.5%3.3%RSF (included in total leasing activity above)821,289354,367483,409884,4081,024,862Previously vacant leasing activity - RSF393,376256,633154,638139,715273,138Top 20 tenants:Annual rental revenue$725,559$768,528$795,244$754,354$741,965Annual rental revenue from investment-grade or publicly traded large cap tenants84%90%89%87%92%Weighted-average remaining lease term (in years) 9.79.49.49.69.3Same property performance - percentage change over comparable quarter from prior year:Net operating income changes(6.0)%(2)(6.0)%(5.4)%(3.1)%0.6%Net operating income changes (cash basis)(1.7)%(2)(3.1)%2.0%5.1%6.3% December 31, 2025December 31, 2025Same Property Financial DataThree Months EndedYear EndedSame Property Statistical DataThree Months EndedYear EndedPercentage change over comparable period from prior year:Number of same properties286282Net operating income changes(6.0)%(3.5)%Rentable square feet30,622,24029,774,548Net operating income changes (cash basis)(1.7)%0.9%(1)Occupancy - current-period average91.0%92.5%Operating margin67%68%Occupancy - same-period prior-year average95.5%95.2% YearRSFPercentage of Occupied RSFAnnual Rental Revenue (per RSF)(1)Percentage of Annual Rental Revenue2026(2)2,900,6659.3%$52.738.2%20273,220,83410.3%$54.529.4%20283,848,08512.4%$51.8010.7%20291,741,4175.6%$46.914.4%20302,482,6338.0%$43.285.7%20313,550,98211.4%$54.1710.3%2032864,8102.8%$58.022.7%20332,164,6966.9%$50.945.9%20342,733,7878.8%$67.669.9%20351,042,1263.3%$57.393.2%Thereafter6,601,76421.2%$84.0929.6% Summary of properties Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSan Francisco Bay AreaMission BayMegacampus: Alexandria Center® for Science and Technology - Mission Bay(1)1,557,403212,796 - 1,770,1998$65,40096.0%96.0%1455(2), 1515(2), 1655, and 1725 Third Street, 1450, 1500, and 1700 Owens Street, and 455 Mission Bay Boulevard SouthMission Bay1,557,403212,796 - 1,770,199865,40096.096.0South San FranciscoMegacampus: Alexandria Center® for Advanced Technologies - South San Francisco812,453 - 107,250919,703542,60079.069.8213(1), 249, 259, 269, and 279 East Grand AvenueAlexandria Center® for Life Science - South San Francisco504,232 - - 504,232328,64283.083.0201 Haskins Way and 400 and 450 East Jamie CourtMegacampus: Alexandria Center® for Advanced Technologies - Tanforan445,232 - - 445,23222,365100.0100.01122 and 1150 El Camino RealAlexandria Technology Center® - Gateway326,197 - - 326,197519,46189.789.7600, 630, 650, 901, and 951 Gateway BoulevardAlexandria Center® for Life Science - Millbrae(1)285,346 - - 285,346137,003100.0100.0230 Harriet Tubman Way500 Forbes Boulevard(1)155,685 - - 155,685110,908100.0100.0South San Francisco2,529,145 - 107,2502,636,39517140,97988.584.9Greater StanfordMegacampus: Alexandria Center® for Life Science - San Carlos738,038 - - 738,038946,67791.491.4825, 835, 960, and 1501-1599 Industrial RoadAlexandria Stanford Life Science District705,787 - - 705,787953,48086.886.83160, 3165, 3170, and 3181 Porter Drive and 3301, 3303, 3305, 3307, and 3330 Hillview Avenue3412, 3420, 3440, 3450, and 3460 Hillview Avenue340,103 - - 340,103524,42986.586.52475 and 2625/2627/2631 Hanover Street and 1450 Page Mill Road198,548 - - 198,548313,751100.0100.02100 and 2200 Geng Road62,526 - - 62,52622,732100.0100.0Greater Stanford2,045,002 - - 2,045,00228141,06990.190.1San Francisco Bay Area6,131,550212,796107,2506,451,59653$347,44890.9%89.4%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.(2)We own 100% of this property. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSan DiegoTorrey PinesMegacampus: One Alexandria Square1,090,906 - - 1,090,90610$77,13896.5%96.5%3115 and 3215(1) Merryfield Row, 3010, 3013, and 3033 Science Park Road, 10935, 10945, 10955, and 10970 Alexandria Way, 10996 Torreyana Road, and 3545 Cray CourtARE Torrey Ridge308,565 - - 308,565314,46186.286.210578, 10618, and 10628 Science Center DriveTorrey Pines1,399,471 - - 1,399,4711391,59994.294.2University Town CenterMegacampus: Campus Point by Alexandria(1)1,310,696893,525 - 2,204,221884,46699.599.59880(2), 10210, 10290, and 10300 Campus Point Drive and 4135, 4155, 4224, and 4242 Campus Point CourtMegacampus: 5200 Illumina Way(1)792,687 - - 792,687629,978100.0100.09625 Towne Centre Drive(1)163,648 - - 163,64816,520100.0100.0University Town Center2,267,031893,525 - 3,160,55615120,96499.799.7Sorrento MesaMegacampus: SD Tech by Alexandria(1)969,41681,610 - 1,051,0261148,07298.098.09605, 9645, 9675, 9725, 9735, 9808, 9855, and 9868 Scranton Road, and 10055, 10065, and 10075 Barnes Canyon RoadMegacampus: Sequence District by Alexandria671,039 - - 671,039624,306100.0100.06290, 6310, 6340, 6350, 6420, and 6450 Sequence DriveSummers Ridge Science Park(1)316,531 - - 316,531411,521100.0100.09965, 9975, 9985, and 9995 Summers Ridge Road10102 Hoyt Park Drive144,113 - - 144,113111,379100.0100.05810/5820 Nancy Ridge Drive83,354 - - 83,35413,389100.0100.09877 Waples Street63,774 - - 63,77412,680100.0100.0Sorrento Mesa2,248,22781,610 - 2,329,83724101,34799.199.1Sorrento Valley3911, 3931, 3985, 4025, 4031, and 4045 Sorrento Valley Boulevard151,406 - - 151,40664,85755.955.911045 Roselle Street27,689 - - 27,68911,814100.0100.0Sorrento Valley179,095 - - 179,09576,67162.762.7San Diego6,093,824975,135 - 7,068,95959$320,58197.2%97.2%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details.(2)We own 100% of this property. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalSeattleLake UnionMegacampus: Alexandria Center® for Life Science - Eastlake1,151,975 - - 1,151,9759$68,69491.3%91.3%1150, 1201(1), 1208(1), 1551, 1600, and 1616 Eastlake Avenue East, 188 and 199 East Blaine Street, and 1600 Fairview Avenue EastMegacampus: Alexandria Center® for Advanced Technologies - South Lake Union413,178227,577 - 640,755423,37298.898.8400(1) and 701 Dexter Avenue North, 428 Westlake Avenue North, and 219 Terry Avenue NorthLake Union1,565,153227,577 - 1,792,7301392,06693.393.3Elliott Bay410 West Harrison Street and 410 Elliott Avenue West20,101 - - 20,101245972.572.5BothellMegacampus: Alexandria Center® for Advanced Technologies - Canyon Park815,000 - - 815,0001915,67484.284.222121 and 22125 17th Avenue Southeast, 22021, 22025, 22026, 22030, 22118, and 22122 20th Avenue Southeast, 22333, 22422, 22515, and 22522 29th Drive Southeast, 22213 and 22309 30th Drive Southeast, and 1629, 1631, 1725, 1916, and 1930 220th Street SoutheastAlexandria Center® for Advanced Technologies - Monte Villa Parkway463,243 - - 463,243612,83479.779.73301, 3303, 3305, 3307, 3555, and 3755 Monte Villa ParkwayBothell1,278,243 - - 1,278,2432528,50882.682.6Other63,057 - - 63,057248191.791.7Seattle2,926,554227,577 - 3,154,13142121,51488.488.4MarylandRockvilleMegacampus: Alexandria Center® for Life Science - Shady Grove1,691,960 - - 1,691,9602093,31594.794.79601, 9603, 9605, 9704, 9708, 9712, 9714, 9800, 9804, 9808, 9900, and 9950 Medical Center Drive, 14920 and 15010 Broschart Road, 9920 Belward Campus Drive, and 9810 and 9820 Darnestown Road1330 Piccard Drive131,507 - - 131,50713,81387.687.61405 Research Boulevard72,170 - - 72,17012,50194.794.71500 and 1550 East Gude Drive91,359 - - 91,35921,844100.0100.05 Research Place63,852 - - 63,85213,125100.0100.05 Research Court51,520 - - 51,52011,976100.0100.012301 Parklawn Drive49,185 - - 49,18511,853100.0100.0Rockville2,151,553 - - 2,151,55327$108,42794.9%94.9%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalMaryland (continued)GaithersburgAlexandria Technology Center® - Gaithersburg I619,061 - - 619,0619$19,66393.6%93.6%9, 25, 35, 45, 50, and 55 West Watkins Mill Road and 910, 930, and 940 Clopper RoadAlexandria Technology Center® - Gaithersburg II486,300 - - 486,300716,25495.195.1700, 704, and 708 Quince Orchard Road and 19, 20, 21, and 22 Firstfield Road401 Professional Drive63,207 - - 63,20711,35179.779.7950 Wind River Lane50,000 - - 50,00011,234100.0100.0620 Professional Drive27,950 - - 27,95011,207100.0100.0Gaithersburg1,246,518 - - 1,246,5181939,70993.993.9Beltsville8000/9000/10000 Virginia Manor Road 191,884 - - 191,88413,30796.496.4101 West Dickman Street(1)142,933 - - 142,93311,72666.566.5Beltsville334,817 - - 334,81725,03383.683.6Maryland3,732,888 - - 3,732,88848153,16993.693.6Research TriangleResearch TriangleMegacampus: Alexandria Center® for Life Science - Durham2,041,067 - - 2,041,0671544,49397.397.36, 8, 10, 12, 14, 40, 41, 42, and 65 Moore Drive, 21, 25, 27, 29, and 31 Alexandria Way, and 2400 Ellis RoadMegacampus: Alexandria Center® for Advanced Technologies and AgTech - Research Triangle711,886 - - 711,886629,58594.194.16, 8, 10, and 12 Davis Drive and 5 and 9 Laboratory DriveMegacampus: Alexandria Center® for Sustainable Technologies259,962 - - 259,96267,34384.884.8104, 108, 110, 112, and 114 TW Alexander Drive and 5 Triangle DriveAlexandria Technology Center® - Alston121,204 - - 121,20422,27980.580.5800 and 801 Capitola DriveAlexandria Innovation Center® - Research Triangle136,563 - - 136,56334,06496.196.17010, 7020, and 7030 Kit Creek Road2525 East NC Highway 5482,996 - - 82,99613,580100.0100.0407 Davis Drive81,956 - - 81,95613,323100.0100.0Research Triangle3,435,634 - - 3,435,63434$94,66795.2%95.2%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalNew York CityNew York CityMegacampus: Alexandria Center® for Life Science - New York City729,461 - - 729,4612$66,08596.4%96.4%430 and 450 East 29th StreetNew York City729,461 - - 729,461266,08596.496.4TexasAustinMegacampus: Intersection Campus1,525,359 - - 1,525,3591233,69483.083.0507 East Howard Lane, 13011 McCallen Pass, 13813 and 13929 Center Lake Drive, and 12535, 12545, 12555, and 12565 Riata Vista CircleAustin1,525,359 - - 1,525,3591233,69483.083.0Greater HoustonAlexandria Center® for Advanced Technologies at The Woodlands 120,828 - 73,298194,12613,17241.525.88800 Technology Forest PlaceTexas1,646,187 - 73,2981,719,4851336,86679.976.5Non-cluster/other markets414,216 - - 414,216712,37991.291.2North America, excluding properties held for sale34,330,8411,998,9151,564,23937,893,9953201,862,05690.9%86.9%Properties held for sale 1,555,377 - - 1,555,3772037,69766.5%66.5%Total - North America35,886,2181,998,9151,564,23939,449,372340$1,899,753 99 Coolidge Avenue311 Arsenal Street50 and 60 Sylvan Road(1)1450 Owens StreetGreater Boston/Cambridge/Inner SuburbsGreater Boston/Cambridge/Inner SuburbsGreater Boston/Route 128San Francisco Bay Area/Mission Bay191,396 RSF333,758 RSF267,015 RSF212,796 RSF81% Leased/Negotiating7% Leased/Negotiating74% Leased/Negotiating49% Leased/Negotiating Our Ownership InterestAt 100%Unlevered YieldsProperty/Market/SubmarketIn ServiceCIPCost to CompleteTotal atCompletionInitial StabilizedInitial Stabilized (Cash Basis)Under construction2026 stabilization with 86% leased/negotiating99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs100%$162,887$210,603$70,510$444,0006.0%6.8%4135 Campus Point Court/San Diego/University Town Center56.4% - 434,46589,535524,0009.4%6.2%10075 Barnes Canyon Road/San Diego/Sorrento Mesa50.0%123,133132,79365,074321,0005.5%5.7%286,020777,8612027-2028 stabilization with 51% leased/negotiating(1)311 Arsenal Street/Greater Boston/Cambridge/Inner Suburbs100%21,854306,028TBD50 and 60 Sylvan Road/Greater Boston/Route 128100% - 345,0461450 Owens Street/San Francisco Bay Area/Mission Bay25.0% - 247,271269 East Grand Avenue/San Francisco Bay Area/South San Francisco100% - 119,546Campus Point by Alexandria/San Diego/University Town Center(2)56.4% - 62,790597,210660,0007.3%6.5%701 Dexter Avenue North/Seattle/Lake Union100% - 302,126TBD21,8541,382,807Evaluating business strategy with 8% leased/negotiating8800 Technology Forest Place/Texas/Greater Houston100%60,93846,5784,484112,0006.3%6.0%3000 Minuteman Road/Greater Boston/Other100% - 163,966TBD40 Sylvan Road/Greater Boston/Route 128100% - 225,791421 Park Drive/Greater Boston/Fenway100% - 584,00960,9381,020,344Total under construction$368,812$3,181,012$2,110,000(3)$5,660,000(3)Our share of investment(3)(4)$310,000$2,710,000$1,710,000$4,730,000 77% of Our Total Development and Redevelopment Pipeline RSF MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionFutureTotal(1)San Francisco Bay AreaMegacampus: Alexandria Center® for Science and Technology - Mission Bay/Mission Bay25.0%$247,271212,796 - 212,7961450 Owens StreetMegacampus: Alexandria Center® for Advanced Technologies - South San Francisco/South San Francisco100%126,201107,25090,000197,250211(2) and 269 East Grand AvenueMegacampus: Alexandria Center® for Advanced Technologies - Tanforan/South San Francisco100%436,956 - 1,930,0001,930,0001122, 1150, and 1178 El Camino RealAlexandria Center® for Life Science - Millbrae/South San Francisco48.6%160,822 - 348,401348,401201 and 231 Adrian Road and 30 Rollins RoadMegacampus: Alexandria Center® for Life Science - San Carlos/Greater Stanford100%486,468 - 1,497,8301,497,830960 Industrial Road, 987 and 1075 Commercial Street, and 888 Bransten Road2100, 2200, 2300, and 2400 Geng Road/Greater Stanford100%83,082 - 240,000240,0001,540,800320,0464,106,2314,426,277San DiegoMegacampus: Campus Point by Alexandria/University Town Center56.4%(3)643,229893,525500,8591,394,38410010(4), 10140(4), 10210, and 10260 Campus Point Drive and 4135, 4161, 4165, and 4224 Campus Point CourtMegacampus: SD Tech by Alexandria/Sorrento Mesa50.0%249,02181,610493,845575,4559805 Scranton Road and 10075 Barnes Canyon Road11255 and 11355 North Torrey Pines Road/Torrey Pines100%161,539 - 215,000215,000Megacampus: One Alexandria Square/Torrey Pines100%65,706 - 125,280125,28010975 and 10995 Torreyana RoadMegacampus: 5200 Illumina Way/University Town Center51.0%17,982 - 451,832451,8329625 Towne Centre Drive/University Town Center30.0%837 - 100,000100,000Megacampus: Sequence District by Alexandria/Sorrento Mesa100%48,992 - 1,661,9151,661,9156290, 6310, 6340, 6350, and 6450 Sequence Drive4075 Sorrento Valley Boulevard/Sorrento Valley100%29,224 - 144,000144,000Other development and redevelopment projects(2)78,036 - 475,000475,000$1,294,566975,1354,167,7315,142,866Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.(2)Includes a property in which we own a partial interest through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. (3)The noncontrolling interest share of our real estate joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases to 75%, after which future capital would be contributed pro rata with our partner.(4)We have a 100% interest in this property. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionFutureTotal(1)SeattleMegacampus: Alexandria Center® for Advanced Technologies - South Lake Union/Lake Union(2)$596,213227,5771,057,4001,284,977601 and 701 Dexter Avenue North and 800 Mercer Street1010 4th Avenue South/SoDo100%62,763 - 544,825544,825410 West Harrison Street/Elliott Bay100% - - 91,00091,000Megacampus: Alexandria Center® for Advanced Technologies - Canyon Park/Bothell100%20,256 - 230,000230,00021660 20th Avenue SoutheastOther development and redevelopment projects100%155,787 - 706,087706,087835,019227,5772,629,3122,856,889MarylandMegacampus: Alexandria Center® for Life Science - Shady Grove/Rockville100%28,382 - 296,000296,0009830 Darnestown Road28,382 - 296,000296,000Research TriangleMegacampus: Alexandria Center® for Life Science - Durham/Research Triangle100%165,816 - 2,060,0002,060,000Megacampus: Alexandria Center® for Advanced Technologies and AgTech - Research Triangle/Research Triangle100%113,493 - 1,170,0001,170,0004 and 12 Davis DriveMegacampus: Alexandria Center® for Sustainable Technologies/Research Triangle100%56,351 - 750,000750,000120 TW Alexander Drive, 2752 East NC Highway 54, and 10 South Triangle DriveOther development and redevelopment projects100%1,647 - 25,00025,000337,307 - 4,005,0004,005,000New York CityMegacampus: Alexandria Center® for Life Science - New York City/New York City100%178,148 - 550,000(3)550,000$178,148 - 550,000550,000Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties.(2)We have a 100% interest in 601 and 701 Dexter Avenue North aggregating 415,977 RSF and a 60% interest in the future development project at 800 Mercer Street aggregating 869,000 RSF.(3)During the three months ended September 30, 2024, we filed a lawsuit against the New York City Health + Hospitals Corporation and the New York City Economic Development Corporation for fraud and breach of contract concerning our option to ground lease a land parcel to develop a future world-class life science building within the Alexandria Center® for Life Science - New York City Megacampus. Refer to our annual report on Form 10-K for the three months ended December 31, 2025 filed with the SEC on January 26, 2026 for additional details. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionFutureTotal(1)TexasAlexandria Center® for Advanced Technologies at The Woodlands/Greater Houston100%$49,69173,298116,405189,7038800 Technology Forest Place1001 Trinity Street and 1020 Red River Street/Austin100%135,868 - 250,010250,010Other development and redevelopment projects100%60,241 - 344,000344,000245,80073,298710,415783,713Other development and redevelopment projects100%47,504 - 597,743597,743Total pipeline as of December 31, 2025, excluding properties held for sale6,788,4643,563,15419,907,13023,470,284Properties held for sale261,208 - 1,893,2811,893,281Total pipeline as of December 31, 2025$7,049,672(2)3,563,15421,800,41125,363,565 Construction spendingProjected Guidance Midpoint for Year Ending December 31, 2026Year Ended December 31, 2025Year Ended December 31, 2024Construction of Class A/A+ properties:Active construction projectsIncludes development and redevelopment under construction(1)$1,445,000$1,216,572$1,791,097Future pipeline pre-constructionPrimarily Megacampus expansion pre-construction work (entitlement, design, and site work)210,000(2)275,971426,948Revenue- and non-revenue-enhancing capital expenditures(3)510,000(4)324,293273,377Construction spending (before contributions from noncontrolling interests or tenants)2,165,0001,816,8362,491,422Contributions from noncontrolling interests (consolidated real estate joint ventures)(100,000)(5)(193,936)(343,798)Tenant-funded and -built landlord improvements(315,000)(178,651)(129,152)Total construction spending$1,750,000$1,444,249$2,018,4722026 guidance range for construction spending$1,500,000 - $2,000,000 Leased/NegotiatingAverage Real Estate Basis Capitalized During 2025Percentage of Total Average Real Estate Basis CapitalizedKey Categories of Real Estate Basis CapitalizedConstruction of Class A/A+ properties:Development and redevelopment of projects under construction:2026 stabilization86%$590,0697%2027-2028 stabilization51%1,308,80016Evaluating business strategy8%878,66111Repositioning and smaller redevelopment projects1,187,460(1)15Future pipeline projects with critical pre-construction milestones during 2026:Megacampus projects2,078,801(2)25Non-Megacampus projects987,518(2)12Assets sold in 2025 or designated as held for sale as of 4Q25(3)1,115,70714Total average real estate basis capitalized(4)$8,147,016100% We hold investments in publicly traded companies and privately held entities primarily involved in the life science industry. The tables below summarize components of our investment income DebtStated RateInterest Rate(1)Maturity Date(2)Principal Payments Remaining for the Periods Ending December 31,PrincipalUnamortized (Deferred Financing Cost), (Discount)/PremiumTotal20262027202820292030ThereafterUnsecured senior line of credit and commercial paper program(3)(3)4.33%(3)1/22/30(3)$ - $ - $ - $ - $353,500$ - $353,500$(339)$353,161Unsecured senior notes payable4.30%4.501/15/26(4)300,000 - - - - - 300,000(36)299,964Unsecured senior notes payable3.80%3.964/15/26350,000 - - - - - 350,000(162)349,838Unsecured senior notes payable3.95%4.131/15/27 - 350,000 - - - - 350,000(555)349,445Unsecured senior notes payable3.95%4.071/15/28 - - 425,000 - - - 425,000(888)424,112Unsecured senior notes payable4.50%4.607/30/29 - - - 300,000 - - 300,000(805)299,195Unsecured senior notes payable2.75%2.8712/15/29 - - - 400,000 - - 400,000(1,655)398,345Unsecured senior notes payable4.70%4.817/1/30 - - - - 450,000 - 450,000(1,686)448,314Unsecured senior notes payable4.90%5.0512/15/30 - - - - 700,000 - 700,000(3,947)696,053Unsecured senior notes payable3.375%3.488/15/31 - - - - - 750,000750,000(3,704)746,296Unsecured senior notes payable2.00%2.125/18/32 - - - - - 900,000900,000(6,043)893,957Unsecured senior notes payable1.875%1.972/1/33 - - - - - 1,000,0001,000,000(6,240)993,760Unsecured senior notes payable2.95%3.073/15/34 - - - - - 800,000800,000(6,477)793,523Unsecured senior notes payable4.75%4.884/15/35 - - - - - 500,000500,000(4,500)495,500Unsecured senior notes payable5.50%5.6610/1/35 - - - - - 550,000550,000(6,316)543,684Unsecured senior notes payable5.25%5.385/15/36 - - - - - 400,000400,000(3,767)396,233Unsecured senior notes payable4.85%4.934/15/49 - - - - - 300,000300,000(2,756)297,244Unsecured senior notes payable4.00%3.912/1/50 - - - - - 700,000700,0009,844709,844Unsecured senior notes payable3.00%3.085/18/51 - - - - - 850,000850,000(10,842)839,158Unsecured senior notes payable3.55%3.633/15/52 - - - - - 1,000,0001,000,000(13,228)986,772Unsecured senior notes payable5.15%5.264/15/53 - - - - - 500,000500,000(7,373)492,627Unsecured senior notes payable5.625%5.715/15/54 - - - - - 600,000600,000(6,470)593,530Unsecured debt weighted-average interest rate/subtotal3.91650,000350,000425,000700,0001,503,5008,850,00012,478,500(77,945)12,400,555Weighted-average interest rate/total 3.91%$650,000$350,000$425,000$700,000$1,503,500$8,850,000$12,478,500$(77,945)$12,400,555Balloon payments$650,000$350,000$425,000$700,000$1,503,500$8,850,000$12,478,500$ - $12,478,500Principal amortization - - - - - - - (77,945)(77,945)Total debt$650,000$350,000$425,000$700,000$1,503,500$8,850,000$12,478,500$(77,945)$12,400,555Fixed-rate debt$650,000$350,000$425,000$700,000$1,150,000$8,850,000$12,125,000$(77,606)$12,047,394Variable-rate debt - - - - 353,500 - 353,500(339)353,161Total debt$650,000$350,000$425,000$700,000$1,503,500$8,850,000$12,478,500$(77,945)$12,400,555Weighted-average stated rate on maturing debt4.03%3.95%3.95%3.50%4.71%3.66% Our Megacampus™ Properties Account for 78% of Our Annual Rental Revenue ALEXANDRIA’SMEGACAMPUS™ PLATFORM REPRESENTS78%OF OUR ANNUAL RENTAL REVENUE COMPANY HIGHLIGHTSPagePageAlexandria's Mission and Cluster Model ..............................................iiiEARNINGS PRESS RELEASEFourth Quarter and Year Ended December 31, 2025 Financial and Operating Results ................................................................................1Consolidated Statements of Operations ..........................................8Guidance ...................................................................................................4Consolidated Balance Sheets............................................................9Dispositions and Sales of Partial Interests ..........................................6Funds From Operations and Funds From Operations per Share 10Earnings Call Information and About the Company ...........................7SUPPLEMENTAL INFORMATIONCompany Profile.......................................................................................13External Growth / Investments in Real EstateInvestor Information .................................................................................14Investments in Real Estate ................................................................31Financial and Asset Base Highlights.....................................................15New Class A/A+ Development and Redevelopment Properties:High-Quality and Diverse Client Base .................................................17Recent Deliveries ...........................................................................33Internal Operating MetricsCurrent Projects..............................................................................35Key Operating Metrics.............................................................................18Summary of Pipeline......................................................................39Same Property Performance..................................................................19Construction Spending........................................................................43Leasing Activity.........................................................................................20Capitalization of Interest .....................................................................44Contractual Lease Expirations ...............................................................22Joint Venture Financial Information...................................................45Top 20 Tenants .........................................................................................23Balance Sheet ManagementSummary of Properties and Occupancy ..............................................24Investments ..........................................................................................47Property Listing ........................................................................................25Balance Sheet ......................................................................................48Key Credit Metrics ...............................................................................49Summary of Debt .................................................................................50Definitions and ReconciliationsDefinitions and Reconciliations..........................................................55 Key considerations for funds from operations and adjusted EBITDA for 1Q26 Three Months EndedYear Ended 12/31/259/30/256/30/253/31/2512/31/2412/31/2512/31/24Revenues: Income from rentals$728,872$735,849$737,279$743,175$763,249$2,945,175$3,049,706Other income25,542(1)16,09524,76114,98325,69681,38166,688Total revenues754,414751,944762,040758,158788,9453,026,5563,116,394Expenses:Rental operations232,543239,234224,433226,395240,432922,605909,265General and administrative28,02029,22429,12830,67532,730117,047168,359Interest65,67454,85255,29650,87655,659226,698185,838Depreciation and amortization322,063340,230346,123342,062330,1081,350,4781,202,380Impairment of real estate1,717,188(2)323,870129,60632,154186,5642,202,818223,068Loss on early extinguishment of debt - 107 - - - 107 - Total expenses2,365,488987,517784,586682,162845,4934,819,7532,688,910Equity in (losses) earnings of unconsolidated real estate joint ventures(304)201(9,021)(507)6,635(9,631)7,059Investment (loss) income(3,890)28,161(30,622)(49,992)(67,988)(56,343)(53,122)Gain on sales of real estate619,914(2)9,366 - 13,165101,806642,445129,312Net (loss) income(995,354)(197,845)(62,189)38,662(16,095)(1,216,726)510,733Net income attributable to noncontrolling interests(85,521)(2)(34,909)(44,813)(47,601)(46,150)(212,844)(187,784)Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s stockholders(1,080,875)(232,754)(107,002)(8,939)(62,245)(1,429,570)322,949Net income attributable to unvested restricted stock awards(965)(2,183)(2,609)(2,660)(2,677)(8,417)(13,394)Net (loss) income attributable to Alexandria Real Estate Equities, Inc.’s common stockholders$(1,081,840)$(234,937)$(109,611)$(11,599)$(64,922)$(1,437,987)$309,555Net (loss) income per share attributable to Alexandria Real Estate Equities, Inc.’s common stockholders:Basic$(6.35)$(1.38)$(0.64)$(0.07)$(0.38)$(8.44)$1.80Diluted$(6.35)$(1.38)$(0.64)$(0.07)$(0.38)$(8.44)$1.80Weighted-average shares of common stock outstanding:Basic170,394170,181170,135170,522172,262170,307172,071Diluted170,394170,181170,135170,522172,262170,307172,071Dividends declared per share of common stock$0.72$1.32$1.32$1.32$1.32$4.68$5.19 Same Property Performance:Net Operating Income ChangesRental Rate Growth: Renewed/Re-Leased SpaceMargins(1)Favorable Lease Structure(2)OperatingAdjusted EBITDAStrategic Lease Structure by Owner and Operator of Collaborative Megacampus Ecosystems69%70%Increasing cash flowsPercentage of leases containing annual rent escalations97%Stable cash flowsLong-Duration Lease Terms(3)Percentage of triple net leases92%9.7 Years7.5 YearsLower capex burdenPercentage of leases providing for therecapture of capital expenditures 92%Top 20 TenantsAll Tenants Incremental Annual Net Operating Income Generated From 2025 Deliveries Consolidated Real Estate Joint VenturesPropertyMarketSubmarketNoncontrolling Interest Share(1)Operating RSF at 100%50 and 60 Binney StreetGreater BostonCambridge/Inner Suburbs66.0%532,39575/125 Binney StreetGreater BostonCambridge/Inner Suburbs60.0%388,270100 and 225 Binney Street and 300 Third StreetGreater BostonCambridge/Inner Suburbs70.0%870,64115 Necco StreetGreater BostonSeaport Innovation District43.3%345,996Alexandria Center® for Science and Technology - Mission Bay(3)San Francisco Bay AreaMission Bay75.0%548,215211 and 213 East Grand AvenueSan Francisco Bay AreaSouth San Francisco70.0%300,930500 Forbes BoulevardSan Francisco Bay AreaSouth San Francisco90.0%155,685Alexandria Center® for Life Science - MillbraeSan Francisco Bay AreaSouth San Francisco51.4%285,3463215 Merryfield RowSan DiegoTorrey Pines70.0%170,523Campus Point by Alexandria(2)(4)San DiegoUniversity Town Center43.6%(5)1,212,4145200 Illumina WaySan DiegoUniversity Town Center49.0%792,6879625 Towne Centre DriveSan DiegoUniversity Town Center70.0%163,648SD Tech by Alexandria(2)(6)San DiegoSorrento Mesa50.0%969,416Summers Ridge Science Park(7)San DiegoSorrento Mesa70.0%316,5311201 and 1208 Eastlake Avenue EastSeattleLake Union70.0%206,134400 Dexter Avenue NorthSeattleLake Union70.0%290,754800 Mercer StreetSeattleLake Union40.0% - (2)Unconsolidated Real Estate Joint VenturesPropertyMarketSubmarketOur Ownership Share(8)Operating RSF at 100%1655 and 1725 Third StreetSan Francisco Bay AreaMission Bay10.0%586,208101 West Dickman StreetMarylandBeltsville58.4%(9)142,933 LiquidityLimited Outstanding Borrowings and Significant Availability on Unsecured Senior Line of Credit(in millions)$5.3B(in millions)Availability under our unsecured senior line of credit, net of amounts outstanding under our commercial paper program$4,647Cash, cash equivalents, and restricted cash554Investments in publicly traded companies95Liquidity as of December 31, 2025$5,296Net Debt and Preferred Stock to Adjusted EBITDA(1)Fixed-Charge Coverage Ratio(1) This section contains additional details for sections throughout the Supplemental Information and the accompanying Earnings Press Release, as well as explanations and reconciliations of certain non- Annual rental revenue Class A/A+ properties and AAA locations Development, redevelopment, and pre-construction (continued) Fixed-charge coverage ratio Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s Initial stabilized yield (unlevered) Investments Investments in real estate Investments in real estate (continued) Joint venture financial information Megacampus™ Net debt and preferred stock to Adjusted EBITDA Net operating income, net operating income (cash basis), and operating margin Net operating income, net operating income (cash basis), and operating margin (continued) Operating statistics Same property comparisons (continued) Stabilized occupancy date Unencumbered net operating income as a percentage of total net operating income Weighted-average shares of common stock outstanding - diluted Alexandria Real Estate Equities, Inc. Reports Solid leasing volume Increased occupancy and leasing progress on temporary vacancy Reduction of capital spend and funding needs Key capital events We will host a conference call on Tuesday, January 27, 2026, at 2:00 p.m. Eastern Time (“ET”)/11:00 a.m. Pacific Time (“PT”), which is open to the general public, to discuss our financial and operating Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a Alexandria’s executive and senior management team consists of 59 Corporate Headquarters New York Stock Exchange Trading Symbol Information Requests26 North Euclid Avenue Common stock: ARE Phone:(626) 578-0777Pasadena, California 91101 Email:corporateinformation@are.comwww.are.com Website:investor.are.com Stable Cash Flows From Our High-Quality and Diverse Mix of TenantsInvestment-Grade or Publicly Traded Large Cap Tenants84%of ARE’s Top 20 Tenant Annual Rental Revenue53%of ARE’s TotalAnnual Rental Revenue Three Months EndedYear EndedYear EndedDecember 31, 2025December 31, 2025December 31, 2024Including Straight-Line RentCash BasisIncluding Straight-Line RentCash BasisIncluding Straight-Line RentCash BasisLeasing activity:Renewed/re-leased space(1) Rental rate changes(9.9)%(2)(5.2)%(2)7.0%3.5%16.9%7.2%New rates$38.58$42.11$52.71$53.66$65.48$64.18Expiring rates$42.82$44.44$49.27$51.87$56.01$59.85RSF821,2892,543,4733,888,139Tenant improvements/leasing commissions$32.26$55.34$46.89Weighted-average lease term5.9 years9.0 years8.5 yearsPreviously vacant/developed/redeveloped space leased(3)New rates$64.08$62.55$72.30$67.56$59.44$57.34Previously vacant RSF393,376944,362672,474Developed/redeveloped RSF6,279704,821493,341Weighted-average lease term8.8 years13.8 years10.0 yearsLeasing activity summary (totals):New rates$46.93$48.80$60.42$59.13$64.16$62.68RSF1,220,9444,192,6565,053,954Weighted-average lease term7.6 years11.9 years8.9 yearsLease expirations(1)Expiring rates$44.66$46.13$54.22$55.56$53.82$57.24RSF911,0294,460,0815,005,638 84% of Top 20 Tenant Annual Rental Revenue Is From Investment-Grade Property/Market/SubmarketLocated on Mega-campusDev/RedevSquare FootagePercentageOccupancy(1)In ServiceCIPTotalLeasedLeased/NegotiatingInitialStabilizedUnder construction2026 stabilization99 Coolidge Avenue/Greater Boston/Cambridge/Inner SuburbsXDev129,413191,396320,80981%81%4Q234Q264135 Campus Point Court/San Diego/University Town CenterXDev - 426,927426,9271001003Q263Q2610075 Barnes Canyon Road/San Diego/Sorrento MesaXDev171,46981,610253,07968681Q252H26300,882699,9331,000,81586862027-2028 stabilization311 Arsenal Street/Greater Boston/Cambridge/Inner SuburbsXRedev56,904333,758390,662772027202750 and 60 Sylvan Road/Greater Boston/Route 128XRedev - 267,015267,01574744Q2620271450 Owens Street/San Francisco Bay Area/Mission BayXDev - 212,796212,796 - 4920272027269 East Grand Avenue/San Francisco Bay Area/South San FranciscoXRedev - 107,250107,250 - - 2H262027Campus Point by Alexandria/San Diego/University Town Center(2)XDev - 466,598466,59810010020282028701 Dexter Avenue North/Seattle/Lake UnionXDev - 227,577227,57723234Q26202756,9041,614,9941,671,8984551Evaluating business strategy8800 Technology Forest Place/Texas/Greater HoustonRedev50,09473,298123,39246462Q234Q263000 Minuteman Road/Greater Boston/OtherXRedev - 453,869453,869 - - 2027202740 Sylvan Road/Greater Boston/Route 128XRedev - 329,049329,049 - - 20272027421 Park Drive/Greater Boston/FenwayXDev - 392,011392,01113132027202850,0941,248,2271,298,32188Total under construction407,8803,563,1543,971,03443%46% reiterated as of January 26, 2026. Actual results may be materially higher or lower than these expectations. Our guidance for 2026 is subject to a number of variables and uncertainties, including, but not limited to, with U.S. generally accepted accounting principles (“GAAP”), including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations attributable to The following table presents a reconciliation of net income (loss) per share attributable to Alexandria’s common stockholders, the most directly comparable financial measure presented in RSFNumber of PropertiesAnnual Rental RevenueMarketOperatingDevelopmentRedevelopmentTotal% of TotalTotal% of TotalPer RSFGreater Boston9,220,527583,4071,383,69111,187,62528%62$709,34737%$89.07San Francisco Bay Area6,131,550212,796107,2506,451,5961653347,4481868.83San Diego6,093,824975,135 - 7,068,9591959320,5811854.14Seattle2,926,554227,577 - 3,154,131842121,514646.95Maryland3,732,888 - - 3,732,888948153,169844.35Research Triangle3,435,634 - - 3,435,63493494,667528.94New York City729,461 - - 729,4612266,085393.96Texas1,646,187 - 73,2981,719,48541336,866228.02Non-cluster/other markets(1)414,216 - - 414,2161712,379132.75Properties held for sale1,555,377 - - 1,555,37742037,697236.46North America35,886,2181,998,9151,564,23939,449,372100%340$1,899,753100%$59.973,563,154 (loss) and non-real estate investments. Refer to “Investments” under “Definitions and reconciliations” in the Supplemental Information for additional details. Debt covenantsUnsecured Senior Notes PayableUnsecured Senior Line of CreditDebt Covenant Ratios(1)RequirementDecember 31, 2025RequirementDecember 31, 2025Total Debt to Total Assets≤ 60%32%≤ 60.0%33.5%Secured Debt to Total Assets≤ 40% - %≤ 45.0% - %Consolidated EBITDA to Interest Expense≥ 1.5x7.8x≥ 1.50x3.41xUnencumbered Total Asset Value to Unsecured Debt≥ 150%302%N/AN/AUnsecured Interest Coverage RatioN/AN/A≥ 1.75x7.63x Alexandria’s opportunistic sale to UCSF, a longstanding tenant, generates proceeds to recycle into the business and enables UCSF to expand its Mission Bay campus. ALEXANDRIA CONTINUES TO HAVE A STRONG AND FLEXIBLE BALANCE SHEET WITH SIGNIFICANT LIQUIDITY CONFERENCE CALLINFORMATION:Tuesday, January 27, 20262:00 p.m. Eastern Time11:00 a.m. Pacific Time(833) 366-1125 or(412) 902-6738Ask to join the conference call for Alexandria Real Estate Equities, Inc.CONTACT INFORMATION:Alexandria Real Estate Equities, Inc.corporateinformation@are.comJOEL S. MARCUSExecutive Chairman &Founder PETER M. MOGLIAChief Executive Officer & Chief Investment OfficerMARC E. BINDAChief Financial Officer & Treasurer PAULA SCHWARTZManaging Director,Rx Communications Group(917) 633-7790 GAAP financial measures and the reasons why we use these supplemental measures of performance and believe they provide useful information to investors. Additional detail can be found in our most recent common stockholders common stockholders (continued) 99 Coolidge Avenue500 North Beacon Street and 4 Kingsbury Avenue(1)Greater Boston/Cambridge/Inner SuburbsGreater Boston/Cambridge/Inner Suburbs129,413 RSF248,018 RSF100% Occupancy92% Occupancy Development and RedevelopmentUnder ConstructionOperating2026 Stabilization2027- 2028 StabilizationEvaluating StrategyFutureSubtotalTotalSquare footageOperating34,330,841 - - - - - 34,330,841Future Class A/A+ development and redevelopment properties - 699,9331,614,9941,248,22719,907,13023,470,28423,470,284Future development and redevelopment square feet currently included in rental properties(1) - - (52,620) - (1,815,084)(1,867,704)(1,867,704)Total square footage, excluding properties held for sale34,330,841699,9331,562,3741,248,22718,092,04621,602,58055,933,421Properties held for sale1,555,377 - - - 1,893,2811,893,2813,448,658Total square footage35,886,218699,9331,562,3741,248,22719,985,32723,495,86159,382,079Investments in real estateGross book value as of December 31, 2025(2)$27,767,849$777,861$1,382,807$1,020,344$3,868,660$7,049,672(3)$34,817,521Properties held for sale452,825 - - - 261,208261,208714,033Total gross investment in real estate, excluding properties held for sale$27,315,024$777,861$1,382,807$1,020,344$3,607,452$6,788,464$34,103,488 As of December 31, 2025Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsInvestments in real estate$3,317,283$83,974Cash, cash equivalents, and restricted cash139,3971,853Other assets402,60210,238Secured notes payable - (60,864)Other liabilities(172,916)(4,524)Redeemable noncontrolling interests(58,788) - $3,627,578$30,677 ALEXANDRIA HAS THE LONGEST WEIGHTED-AVERAGE REMAINING DEBT TERM Fixed-rate and variable-rate debtFixed-RateDebtVariable-Rate DebtTotalPercentageWeighted-AverageInterest Rate(1)Remaining Term(in years)Unsecured senior notes payable$12,047,394$ - $12,047,39497.2%3.90%12.3Unsecured senior line of credit(2) and commercial paper program(3) - 353,161353,1612.84.334.1(4)Total/weighted average$12,047,394$353,161$12,400,555100.0%3.91%12.1(4)Percentage of total debt97.2%2.8%100.0% results for the fourth quarter and year ended December 31, 2025. To participate in this conference call, dial (833) 366-1125 or (412) 902-6738 shortly before 2:00 p.m. ET/11:00 a.m. PT and ask the operator to join 4Q25 and 2025 Net Loss per Share - Diluted of $6.35 and $8.44, respectively; and leasing velocity and overall tenant demand, actions and changes in policy by the current U.S. administration related to the regulatory environment, life science funding, the U.S. Food and Drug Administration and 12/31/259/30/256/30/253/31/2512/31/24Assets Investments in real estate$28,689,996$31,743,917$32,160,600$32,121,712$32,110,039Investments in unconsolidated real estate joint ventures30,67739,60140,23450,08639,873Cash and cash equivalents549,062579,474520,545476,430552,146Restricted cash4,6934,7057,4037,3247,701Tenant receivables6,6726,4096,2676,8756,409Deferred rent1,179,4031,257,3781,232,7191,210,5841,187,031Deferred leasing costs458,311505,241491,074489,287485,959Investments1,501,2491,537,6381,476,6961,479,6881,476,985Other assets 1,661,7721,700,7851,688,0911,758,4421,661,306Total assets$34,081,835$37,375,148$37,623,629$37,600,428$37,527,449Liabilities, Noncontrolling Interests, and EquitySecured notes payable$ - $ - $153,500$150,807$149,909Unsecured senior notes payable12,047,39412,044,99912,042,60712,640,14412,094,465Unsecured senior line of credit and commercial paper353,1611,548,5421,097,993299,883 - Accounts payable, accrued expenses, and other liabilities2,397,0732,432,7262,360,8402,281,4142,654,351Dividends payable127,771230,603229,686228,622230,263Total liabilities14,925,39916,256,87015,884,62615,600,87015,128,988Commitments and contingenciesRedeemable noncontrolling interests58,78858,6629,6129,61219,972Alexandria Real Estate Equities, Inc.’s stockholders’ equity:Common stock1,7051,7031,7011,7011,722Additional paid-in capital15,497,76016,669,80217,200,94917,509,14817,933,572Accumulated other comprehensive loss(29,395)(32,203)(27,415)(46,202)(46,252)Alexandria Real Estate Equities, Inc.’s stockholders’ equity15,470,07016,639,30217,175,23517,464,64717,889,042Noncontrolling interests3,627,5784,420,3144,554,1564,525,2994,489,447Total equity19,097,64821,059,61621,729,39121,989,94622,378,489Total liabilities, noncontrolling interests, and equity$34,081,835$37,375,148$37,623,629$37,600,428$37,527,449 best-in-class, mission-driven life science REIT making a positive and lasting impact on the Is Within Our Megacampus™ Ecosystems We present certain operating statistics related to our properties, including number of Unencumbered net operating income as a percentage of total net operating income is a non- Alexandria’s common stockholders - diluted, and funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted, for the periods below: accordance with GAAP, including our share of amounts from consolidated and unconsolidated real estate joint ventures, to funds from operations per share attributable to Alexandria’s common Furthermore, we believe net operating income is useful to investors as a performance •Leasing volume of 1.2 million RSF during 4Q25. individuals averaging 24 years of real estate experience, including 13 years Net debt and preferred stock to Adjusted EBITDA is a non-GAAP financial measure that we Annual rental revenue represents the annualized fixed base rental obligations, calculated in Class A/A+ properties are properties clustered in AAA locations that provide innovative Initial stabilized yield is calculated as the estimated amounts of net operating income at The following table reconciles net income (loss) to net operating income and net operating The stabilized occupancy date represents the estimated date on which a development or From time to time, we enter into capital market transactions, including forward equity sales Operating occupancy as of September 30, 202590.6%Assets with vacancy designated as held for sale or sold during 4Q250.5Early termination of one lease aggregating 170,618 RSF at 259 East Grand Avenue in South San Francisco, originally set to expire in early 2027, which is already fully re-leased to a new tenant with occupancy expected to commence in 2H26(0.5)(1)Reclassification of 401 Park Avenue from redevelopment to operating upon our decision to pursue leasing as office space rather than convert to laboratory space(0.3)Other changes in occupancy, primarily due to the commencement of leases during 4Q250.6Operating occupancy as of December 31, 202590.9Key vacant space leased with future delivery2.5(2)Operating occupancy as of December 31, 2025, including leased but not yet delivered space93.4% •During 4Q25, we reduced future construction funding requirements across our active pipeline •On December 8, 2025, we announced that our board of directors authorized a common stock Fixed-charge coverage ratio is a non-GAAP financial measure representing the ratio of December 31, 2025Year Ended December 31, 2024Three Months EndedYear EndedRealized (losses) gains:Realized gains$21,072$115,722$117,214Impairment of non-real estate investments(20,181)(1)(95,716)(58,090)Significant realized loss(103,329)(2)(103,329)(2) - (102,438)(83,323)59,124Unrealized gains (losses)98,548(3)26,980(4)(112,246)(5)Investment loss$(3,890)$(56,343)$(53,122) annual report on Form 10-K and subsequent quarterly reports on Form 10-Q, as well as other documents filed with or furnished to the SEC from time to time. Revenue-enhancing and repositioning capital expenditures represent spending to reposition The following table reconciles our investments in real estate as of December 31, 2025: The square footage presented in the table below is classified as operating as of December 31, We present components of balance sheet and operating results information related to our real A Megacampus ecosystem is a cluster campus that consists of approximately 1 million RSF or The following table reconciles the number of same properties to total properties for the year We hold investments in publicly traded companies and privately held entities primarily The following key considerations are expected to impact our quarterly funds from operations per share results in 1Q26. These items will also affect our Adjusted EBITDA beginning in Aggregated $78 Million(1), Including $10 Million in 4Q25 the call for Alexandria Real Estate Equities, Inc. The audio webcast can be accessed at www.are.com in the “For Investors” section. A replay of the call will be available for a limited time from 4:00 p.m. ET/1:00 p.m. National Institutes of Health, trade, and other areas. For additional discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated, refer to our discussion of 4Q25 and 2025 FFO per Share - Diluted, as Adjusted, of $2.16 and $9.01, respectively world. With our founding in 1994, Alexandria pioneered the life science real estate niche. properties, RSF, occupancy percentage, leasing activity, and contractual lease expirations as of the end GAAP financial measure that we believe is useful to investors as a performance measure of the results measure of our consolidated properties because, when compared across periods, net operating income $767.1M$180.3M(Our Share)(1)SALES PRICE IN 4Q25$1,645SALES PRICE PER RSF$416.7M$103.9M(Our Share)GAIN ON SALE OFREAL ESTATE$293.0MARE ORIGINAL PURCHASE PRICE (2011)40%OCCUPANCY AS OF 3Q25 35 COMPLETEDTRANSACTIONS(1)$1.8BTOTAL SALES(1)$642MTOTAL GAIN ON SALES OF REAL ESTATE(1) stockholders - diluted, and funds from operations per share attributable to Alexandria’s common stockholders - diluted, as adjusted, for the periods below. Per share amounts may not add due to or Publicly Traded Large Cap Tenants(1) believe is useful to investors as a supplemental measure of evaluating our balance sheet leverage. Net accordance with GAAP. It includes the amortization of deferred revenue related to tenant-funded and tenants with highly dynamic and collaborative environments that enhance their ability to successfully stabilization divided by our investment in the property. For this calculation, we exclude any tenant- income (cash basis) and computes operating margin: redevelopment project is expected to reach occupancy of 95% or greater. agreements (“Forward Agreements”), to fund acquisitions, to fund construction of our development and •Leasing of previously vacant space aggregating 393,376 RSF, up 98%, over the quarterly Adjusted EBITDA to cash interest and fixed charges. We believe that this ratio is useful to investors as a GAAP-basis accounting for real estate assets utilizes historical cost accounting and assumes by: i) selling or designating as held for sale three projects and ii) pivoting one project to a repurchase program under which we may repurchase up to $500.0 million of our common with Alexandria. Our executive management team alone averages 15 years or significantly change the use of a property, including through improvement in the asset quality from The following table reconciles net income (loss) to funds from operations for the share of 2025. These lease expirations or vacant space at recently acquired properties represent future estate joint ventures, which are not presented, or intended to be presented, in accordance with GAAP. greater, including operating, active development/redevelopment, and land RSF less operating RSF ended December 31, 2025: Three Months EndedYear Ended12/31/259/30/256/30/253/31/2512/31/2412/31/2512/31/24Net (loss) income attributable to Alexandria’s common stockholders - basic and diluted$(1,081,840)$(234,937)$(109,611)$(11,599)$(64,922)$(1,437,987)$309,555Depreciation and amortization of real estate assets319,865338,182343,729339,381327,1981,341,1571,191,524Noncontrolling share of depreciation and amortization from consolidated real estate JVs(39,942)(45,327)(36,047)(33,411)(34,986)(154,727)(129,711)Our share of depreciation and amortization from unconsolidated real estate JVs8558529421,0541,0613,7034,238Gain on sales of real estate(307,132)(1)(9,824) - (13,165)(100,109)(330,121)(127,615)Impairment of real estate - rental properties and land1,439,303(2)323,870131,090 - 184,5321,894,263192,455Allocation to unvested restricted stock awards (1,903)(1,648)(1,222)(686)(1,182)(5,681)(8,696)Funds from operations attributable to Alexandria’s common stockholders - diluted(3)329,206371,168328,881281,574311,5921,310,6071,431,750Unrealized (gains) losses on non-real estate investments(98,548)(18,515)21,93868,14579,776(26,980)112,246Significant realized losses on non-real estate investments103,329(4) - - - - 103,329 - Impairment of non-real estate investments20,181(5)25,13939,21611,18020,26695,71658,090Impairment of real estate12,619(2) - 7,18932,1542,03251,96230,613Loss on early extinguishment of debt - 107 - - - 107 - Acceleration of stock compensation expense due to executive officer resignation2,455(6) - - - - 2,455 - (Decrease) increase in provision for expected credit losses on financial instruments(341) - - 285(434)(56)(434)Allocation to unvested restricted stock awards(363)(74)(794)(1,329)(1,407)(2,476)(3,188)Funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted$368,538$377,825$396,430$392,009$411,825$1,534,664$1,629,077 This long-term lease at 700 Quince Orchard Road demonstrates AstraZeneca’s commitment to Maryland and brings its aggregate footprint across multiple Alexandria cluster markets to over 600,000 RSF involved in the life science industry. We recognize, measure, present, and disclose these investments as AMONG S&P 500 REITS AT OVER 2X THE AVERAGE DEBT TERM FOR THESE REITS 1Q26. As a result, we expect our net debt and preferred stock to Adjusted EBITDA ratio to temporarily increase in 1Q26 (on a quarter annualized basis) by approximately 1.0x to 1.5x higher PT on Tuesday, January 27, 2026. The replay number is (855) 669-9658 or (412) 317-0088, and the access code is 4730896. ALEXANDRIA’S DEVELOPMENT AND REDEVELOPMENT DELIVERIES ARE EXPECTED TO PROVIDE INCREMENTAL GROWTH IN ANNUAL NET OPERATING INCOME “forward-looking statements” on page 7 of the Earnings Press Release as well as our SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. (In thousands)Investments in Real EstateGross investments in real estate$34,817,521Less: accumulated depreciation(6,127,525)Investments in real estate$28,689,996 of the period. We believe these measures are useful to investors because they facilitate an of operations of our unencumbered real estate assets as it reflects those income and expense items that Alexandria is the preeminent and longest-tenured owner, operator, and developer of reflects trends in occupancy rates, rental rates, and operating costs, which provide a perspective not debt and preferred stock is equal to the sum of total consolidated debt less cash, cash equivalents, and tenant-built landlord improvements for leases in effect as of the end of the period, related to our recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success. These funded and tenant-built landlord improvements from our investment in the property. Our initial stabilized redevelopment projects, and for general working capital purposes. While the Forward Agreements are rounding. that real estate values diminish over time. In an effort to overcome the difference between real estate average over the last five quarters. MarketProperty/SubmarketOur Ownership InterestBook ValueSquare FootageDevelopment and RedevelopmentUnder ConstructionFutureTotal(1)Greater BostonMegacampus: The Arsenal on the Charles/Cambridge/Inner Suburbs100%$318,404333,75834,157367,915 311 Arsenal StreetMegacampus: 480 Arsenal Way and 446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue/Cambridge/Inner Suburbs100%234,388191,396560,000751,396446, 458, and 500 Arsenal Street, and 99 Coolidge AvenueMegacampus: Alexandria Center® for Life Science - Fenway/Fenway100%584,009392,011 - 392,011421 Park DriveMegacampus: Alexandria Center® for Life Science - Waltham/Route 128100%635,997596,064515,0001,111,06440, 50, and 60 Sylvan Road, and 35 Gatehouse DriveMegacampus: 30, 200, and 3000 Minuteman Road/Other100%222,659453,869608,5411,062,4103000 Minuteman RoadMegacampus: Alexandria Technology Square®/Cambridge100%8,631 - 100,000100,00010 Necco Street/Seaport Innovation District100%107,099 - 175,000175,000215 Presidential Way/Route 128100%6,816 - 112,000112,000Other development and redevelopment projects100%162,935 - 740,000740,000$2,280,9381,967,0982,844,6984,811,796Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details.(1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties. supplemental measure of our ability to satisfy fixed financing obligations and preferred stock dividends. Adjusted EBITDA and Adjusted EBITDA margin We believe Adjusted EBITDA provides investors with relevant and useful information as it Weighted-Average Remaining Term of 12.1 Years lower investment strategy; enabling us to redeploy future construction savings and sale stock through December 31, 2026. The new program replaces the prior repurchase Class B to Class A/A+. consolidated real estate joint ventures attributable to noncontrolling interests and our share of opportunities for which we have the intent, subject to market conditions and leasing, to commence first- We present the proportionate share of certain financial line items as follows: (i) for each real estate joint expected to be demolished. We consider Megacampuses that include a minimum of 750,000 operating Market / Submarket / AddressRSF Number of PropertiesAnnual Rental RevenueOccupancy Percentage OperatingOperating and RedevelopmentOperatingDevelopmentRedevelopmentTotalGreater BostonCambridge/Inner SuburbsMegacampus: Alexandria Center® at Kendall Square2,213,866 - - 2,213,8668$212,45893.7%93.7%50(1), 60(1), 75/125(1), 90, 100(1), and 225(1) Binney Street, 140 First Street, and 300 Third Street(1)Megacampus: Alexandria Center® at One Kendall Square1,294,598 - - 1,294,59811136,03491.291.2One Kendall Square (Buildings 100, 200, 300, 400, 500, 600/700, 1400, 1800, and 2000), and 325 and 399 Binney StreetMegacampus: Alexandria Technology Square®1,192,075 - - 1,192,075779,34173.973.9100, 200, 300, 400, 500, 600, and 700 Technology Square Megacampus: The Arsenal on the Charles787,760 - 333,7581,121,5181346,02078.054.8 311, 321, and 343 Arsenal Street, 300, 400, and 500 North Beacon Street, 1, 2, 3, and 4 Kingsbury Avenue, and 100, 200, and 400 Talcott AvenueMegacampus: 480 Arsenal Way, 446, 458, and 500 Arsenal Street, and 99 Coolidge Avenue(1)386,780191,396 - 578,176526,29891.491.4Cambridge/Inner Suburbs5,875,079191,396333,7586,400,23344500,15186.982.2FenwayMegacampus: Alexandria Center® for Life Science - Fenway1,452,183392,011 - 1,844,1943104,65179.279.2401 and 421 Park Drive and 201 Brookline AvenueSeaport Innovation District5 and 15(1) Necco Street459,395 - - 459,395247,01997.097.0Route 128Megacampus: Alexandria Center® for Life Science - Waltham465,981 - 596,0641,062,045538,56697.842.940, 50, and 60 Sylvan Road, 35 Gatehouse Drive, and 840 Winter Street19, 225, and 235 Presidential Way585,226 - - 585,226314,19497.097.0Route 1281,051,207 - 596,0641,647,271852,76097.462.1OtherMegacampus: 30, 200, and 3000 Minuteman Road382,663 - 453,869836,53254,76662.528.6Greater Boston9,220,527583,4071,383,69111,187,62562$709,34786.4%75.1%Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details.(1)We own a partial interest in this property through a real estate joint venture. Refer to “Joint venture financial information” in the Supplemental Information for additional details. follows: PASADENA, Calif. - January 26, 2026 - Alexandria Real Estate Equities, Inc. (NYSE: ARE) with Alexandria. than our 4Q25 annualized ratio of 5.7x. We expect this ratio to trend downward through the remainder of 2026 as we make progress on our disposition and sales of partial interests program, Alexandria’s Leasing Volume Is Driven by Our Diverse Tenant Mix Three Months EndedYear Ended(Dollars in thousands)12/31/2512/31/2412/31/2512/31/24Net (loss) income$(995,354)$(16,095)$(1,216,726)$510,733Equity in losses (earnings) of unconsolidated real estate joint ventures304(6,635)9,631(7,059)General and administrative expenses28,02032,730117,047168,359Interest expense65,67455,659226,698185,838Depreciation and amortization322,063330,1081,350,4781,202,380Impairment of real estate1,717,188186,5642,202,818223,068Loss on early extinguishment of debt - - 107 - Gain on sales of real estate(619,914)(101,806)(642,445)(129,312)Investment loss3,89067,98856,34353,122Net operating income521,871548,5132,103,9512,207,129Straight-line rent revenue(14,096)(17,653)(73,476)(143,329)Amortization of deferred revenue related to tenant-funded and -built landlord improvements(5,264)(1,214)(14,771)(1,543)Amortization of acquired below-market leases(5,889)(15,512)(37,763)(85,679)Provision for expected credit losses on financial instruments(341)(434)(56)(434)Net operating income (cash basis)$496,281$513,700$1,977,885$1,976,144Net operating income (cash basis) - annualized$1,985,124$2,054,800$1,977,885$1,976,144Net operating income (from above)$521,871$548,513$2,103,951$2,207,129Total revenues$754,414$788,945$3,026,556$3,116,394Operating margin69%70%70%71% understanding of certain trends for our properties. We compute the number of properties, RSF, Redevelopment - placed intoDevelopment - under constructionPropertiesservice after January 1, 2024Properties99 Coolidge Avenue1840 Winter Street11450 Owens Street1Alexandria Center® for Advanced Technologies - Monte Villa Parkway610075 Barnes Canyon Road1421 Park Drive174135 Campus Point Court1Acquisitions after January 1, 2024Properties701 Dexter Avenue North1Other2Campus Point by Alexandria - 26Unconsolidated real estate JVs3Development - placed intoProperties held for sale20service after January 1, 2024PropertiesTotal properties excluded from same properties581150 Eastlake Avenue East19810 Darnestown Road1Same properties2829820 Darnestown Road1Total properties in North America as of December 31, 20253404155 Campus Point Court1201 Brookline Avenue19808 Medical Center Drive1230 Harriet Tubman Way1500 North Beacon Street and 4 Kingsbury Avenue210935, 10945, and 10955 Alexandria Way312Redevelopment - under constructionProperties40, 50, and 60 Sylvan Road3269 East Grand Avenue18800 Technology Forest Place1311 Arsenal Street1Other28 are incurred at the unencumbered property level. Unencumbered net operating income is derived from immediately apparent from net income or loss. Net operating income can be used to measure the initial collaborative Megacampus™ ecosystems in AAA life science innovation cluster locations, restricted cash, plus preferred stock outstanding as of the end of the period. Refer to the definition of operating RSF. Annual rental revenue is presented using 100% of the annual rental revenue from our properties are typically well-located, professionally managed, and well-maintained, offering a wide range yield excludes the benefit of leverage. Our cash rents related to our development and redevelopment Tenant recoveries outstanding, we are required to consider the potential dilutive effect of our Forward Agreements under values and historical cost accounting for real estate assets, the Nareit Board of Governors established Cash interest is equal to interest expense calculated in accordance with GAAP plus capitalized interest, allows investors to evaluate the operating performance of our business activities without having to •Rental rates on renewals and re-leasing of space decreased by 9.9% and 5.2% (cash basis) unconsolidated real estate joint ventures: time conversion from non-laboratory space to laboratory space, or to commence future ground-up venture that we consolidate in our financial statements, which are controlled by us through contractual RSF to be Established Megacampuses. These Megacampuses have realized the scale and flexibility proceeds into opportunities aligned with our long‑term Megacampus™ strategy. authorization for up to $500.0 million that was set to expire on December 31, 2025. During Statements of OperationsBalance SheetGains and LossesCarrying AmountUnrealizedRealizedDifference between proceeds received upon disposition and historical costPublicly traded companiesFair valueChanges in fair valuePrivately held entities without readily determinable fair values that:Report NAVFair value, using NAV as a practical expedientChanges in NAV, as a practical expedient to fair valueDo not report NAVCost, adjusted for observable price changes and impairments(1)Observable price changes(1)Impairments to reduce costs to fair value, which result in an adjusted cost basis and the differences between proceeds received upon disposition and adjusted or historical costEquity method investmentsContributions, adjusted for our share of the investee’s earnings or losses, less distributions received, reduced by other-than-temporary impairments Our share of unrealized gains or losses reported by the investeeOur share of realized gains or losses reported by the investee, and other-than-temporary impairments Additionally, a copy of this Earnings Press Release and Supplemental Information for the fourth quarter and year ended December 31, 2025 is available in the “For Investors” section of our website at announced financial and operating results for the fourth quarter and year ended December 31, REDUCED FUTURE CONSTRUCTION COMMITMENTS BY MORE THAN $300 MILLION FROM FOUR PROJECTS with a target net debt and preferred stock to Adjusted EBITDA ratio of 5.6x to 6.2x for 4Q26 annualized, which is unchanged from our initial 2026 guidance provided on December 3, 2025. Projected 2026 Funds From Operations per Share Attributable to Alexandria’s Common Stockholders - DilutedFunds from operations per share, as adjusted(1)$6.25 to $6.55Midpoint$6.40 Key Credit Metric TargetsNet debt and preferred stock to Adjusted EBITDA - 4Q26 annualized5.6x to 6.2xFixed-charge coverage ratio - 4Q26 annualized3.6x to 4.1x The following table reconciles net income (loss), the most directly comparable financial occupancy percentage, leasing activity, and contractual lease expirations at 100%, excluding RSF at assets classified in continuing operations, which are not subject to any mortgage, deed of trust, lien, or stabilized yields of our properties by calculating net operating income generated by a property divided by funds from operations as an improved measurement tool. Since its introduction, funds from operations Adjusted EBITDA and Adjusted EBITDA margin for further information on the calculation of Adjusted consolidated properties and our share of annual rental revenue for our unconsolidated real estate joint of amenities and featuring premium construction materials and finishes. Class A/A+ properties are projects are generally expected to increase over time due to contractual annual rent escalations. Our the treasury stock method. Under this method, we also include the dilutive effect of unvested restricted including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland, EXECUTIVE MANAGEMENT TEAMJoel S. MarcusPeter M. MogliaExecutive Chairman & FounderChief Executive Officer & Chief Investment OfficerHunter L. KassHart ColeCo-President & Regional Market Director - Greater BostonCo-President & Co-Regional Market Director - SeattleMarc E. BindaLawrence J. DiamondChief Financial Officer & TreasurerCo-Chief Operating Officer & Regional Market Director - MarylandJoseph HakmanJesse J. NelsonCo-Chief Operating Officer & Chief Strategic Transactions OfficerEVP - Regional Market Director - San FranciscoMichael E. BossBret E. GossettEVP - Co-Regional Market Director - San DiegoEVP - Co-Regional Market Director & Head of Leasing - San DiegoBlake L. StevensJoshua J. MitchellEVP - Regional Market Director - Research TriangleEVP - Regional Market Director - New YorkHallie E. KuhnJenna R. FogerEVP - Capital Markets & Co-Lead - Life ScienceEVP - Co-Lead - Life ScienceJackie B. ClemGary D. DeanGeneral Counsel & SecretaryEVP - Real Estate Legal AffairsAndres R. GavinetOnn C. LeeChief Accounting OfficerEVP - AccountingKristina A. Fukuzaki-CarlsonMadeleine T. AlsbrookEVP - Business OperationsEVP - Talent ManagementGregory C. ThomasEVP - Chief Technology Officer TenantRemaining Lease Term(1) (in years)Aggregate RSFAnnual Rental Revenue(1)Percentage of Annual Rental Revenue(1)Investment-Grade Credit RatingsAverage Market Cap(in billions)Moody’sS&P1Bristol-Myers Squibb Company5.61,344,987$116,1406.1%A2A$102.642Eli Lilly and Company9.31,000,59184,9284.5Aa3A+$784.243Moderna, Inc.12.9462,10071,5713.8 - - $11.324Takeda Pharmaceutical Company Limited9.4549,75947,8992.5Baa1BBB+$46.085Eikon Therapeutics, Inc.(2)13.1311,80640,0052.1 - - $ - 6AstraZeneca PLC6.1440,08739,4132.1A1A+$237.137Illumina, Inc.5.8792,68729,9771.6Baa3BBB$15.918Novartis AG2.1377,09529,4631.6Aa3AA-$251.269United States Government4.6414,49929,243(3)1.5AaaAA+$ - 10Uber Technologies, Inc.56.8(4)1,009,18827,8311.5Baa1BBB$176.4411Boston Children's Hospital11.2309,23126,2941.4Aa2AA$ - 12Sanofi5.0267,27821,8511.2Aa3AA$125.2913Alphabet Inc.2.4418,60021,8371.1Aa2AA+$2,562.4214New York University6.6218,98321,1101.1Aa2AA-$ - 15Cloud Software Group Holdings, Inc.0.7(5)216,27820,5531.1 - - $ - 16Massachusetts Institute of Technology4.0242,42820,5291.1AaaAAA$ - 17Charles River Laboratories, Inc.9.7242,69320,2071.1 - - $7.9718Merck & Co., Inc.8.0308,35619,6101.0Aa3A+$219.0919Vaxcyte, Inc.9.0230,75518,6921.0 - - $6.0920Altos Labs, Inc.(6)15.3158,99018,4061.0 - - $ - Total/weighted-average9.7(4)9,316,391$725,55938.4% less amortization of loan fees and debt premiums (discounts). account for differences recognized because of investing and financing decisions related to our real Three Months EndedYear Ended12/31/259/30/256/30/253/31/2512/31/2412/31/2512/31/24Net (loss) income per share attributable to Alexandria’s common stockholders - diluted$(6.35)$(1.38)$(0.64)$(0.07)$(0.38)$(8.44)$1.80Depreciation and amortization of real estate assets1.651.731.811.801.706.996.20Gain on sales of real estate(1.80)(0.06) - (0.08)(0.58)(1.94)(0.74)Impairment of real estate - rental properties and land8.451.900.77 - 1.0711.121.12Allocation to unvested restricted stock awards(0.02)(0.01)(0.01) - - (0.04)(0.06)Funds from operations per share attributable to Alexandria’s common stockholders - diluted1.932.181.931.651.817.698.32Unrealized (gains) losses on non-real estate investments(0.58)(0.11)0.130.400.46(0.16)0.65Significant realized losses on non-real estate investments0.61 - - - - 0.62 - Impairment of non-real estate investments0.120.150.230.070.120.560.34Impairment of real estate0.07 - 0.040.190.010.300.18Acceleration of stock compensation expense due to executive officer resignation0.01 - - - - 0.01 - Allocation to unvested restricted stock awards - - - (0.01)(0.01)(0.01)(0.02)Funds from operations per share attributable to Alexandria’s common stockholders - diluted, as adjusted$2.16$2.22$2.33$2.30$2.39$9.01$9.47Weighted-average shares of common stock outstanding - dilutedEarnings per share - diluted170,394170,181170,135170,522172,262170,307172,071Funds from operations - diluted, per share170,504170,305170,192170,599172,262170,390172,071Funds from operations - diluted, as adjusted, per share170,504170,305170,192170,599172,262170,390172,071 for 4Q25 and increased by 7.0% and 3.5% (cash basis) for 2025. Non-revenue-enhancing capital expenditures represent costs required to maintain the current development: rights or majority voting rights, but of which we own less than 100%, we apply the noncontrolling interest that deliver strategic optionality to our tenants. We present certain metrics related to our Established •We reduced the overall size of our future construction funding needs on current 4Q25, no shares were repurchased. www.are.com or by following this link: https://www.are.com/fs/2025q4.pdf. 2025. Tenant recoveries represent revenues comprising reimbursement of real estate taxes, Property/Market/SubmarketOur Ownership InterestRSF Placed in ServiceOccupancy Percentage(3)Total ProjectUnlevered Yields4Q25 Delivery Date(2)Prior to 1/1/251Q252Q253Q254Q25TotalInitial StabilizedInitial Stabilized (Cash Basis)RSFInvestmentDevelopment projects99 Coolidge Avenue/Greater Boston/Cambridge/Inner SuburbsN/A100%116,414 - - 12,999 - 129,413100%320,809$444,0006.0%6.8%500 North Beacon Street and 4 Kingsbury Avenue/Greater Boston/Cambridge/Inner SuburbsN/A100%211,574 - - 36,444 - 248,01892%248,018429,0006.55.9230 Harriet Tubman Way/San Francisco Bay Area/South San FranciscoN/A48.6% - 285,346 - - - 285,346100%285,346476,0007.56.210935, 10945, and 10955 Alexandria Way/San Diego/Torrey PinesN/A100%93,492 - 119,202122,302 - 334,996100%334,996480,0007.26.910075 Barnes Canyon Road/San Diego/Sorrento Mesa12/18/2550.0% - 17,718 - 13,772139,979171,469100%253,079321,0005.55.7Weighted average/total12/18/25421,480303,064119,202185,517139,9791,169,2421,442,248$2,150,0006.6%6.3%Assets sold in 2025 or designated as held for sale in 4Q25:651 Gateway Boulevard/San Francisco Bay Area/South San Francisco(4)N/AN/A67,017 - 22,005 - - 89,022N/ACanada(5)N/AN/A78,4876,43076,567 - - 161,484N/A measure calculated and presented in accordance with GAAP, to Adjusted EBITDA and calculates the Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsDecember 31, 2025December 31, 2025(In thousands)Three Months EndedYear EndedThree Months EndedYear EndedNet income (loss)$85,521$212,844$(304)$(9,631)Depreciation and amortization of real estate assets39,942154,7278553,703Gain on sale of real estate of consolidated JV(312,807)(312,807) - - Gain on sale of interest of unconsolidated JV - - (25)(483)Impairment of real estate265,266265,266 - 8,673Funds from operations$77,922$320,030$526$2,262 properties classified as held for sale, for all properties in which we have an investment, including other security interest, as of the period for which income is presented. our investment in the property. Net operating income excludes certain components from net income in has become a widely used non-GAAP financial measure among equity REITs. We believe that funds Maintain a Strong andFlexible Balance Sheet,Significant Liquidity, and Targeted Leverage EBITDA. ventures. Annual rental revenue per RSF is computed by dividing annual rental revenue by the sum of generally newer or have undergone substantial redevelopment and are generally expected to command estimates for initial stabilized yields, initial stabilized yields (cash basis), and total costs at completion stock awards (“RSAs”) with forfeitable dividends in the calculation of diluted shares. Research Triangle, and New York City. estate and non-real estate investments, our capital structure, capital market transactions, and variances revenues of a stabilized property, including the associated costs for renewed and re-leased space. economic ownership percentage to each financial item to arrive at the amount of such cumulative Megacampuses because we believe they facilitate a more robust understanding of certain of our •82% of our leasing activity during the last twelve months was generated from our existing Continue to SuccessfullyManage G&A Dev/RedevRSF of Lease Expirations Targeted forDevelopment and RedevelopmentProperty/Submarket20262027Thereafter(1)TotalUnder construction project:Campus Point by Alexandria/University Town CenterDev52,620 - - 52,620Future projects:446, 458, and 500 Arsenal Street/Cambridge/Inner SuburbsDev - - 116,623116,6233000 Minuteman Road/Greater BostonRedev - - 167,549167,5491122 and 1150 El Camino Real/South San FranciscoDev - - 375,232375,2322100 and 2200 Geng Road/Greater Stanford Dev - - 62,52662,526960 Industrial Road/Greater StanfordDev - - 112,590112,590Campus Point by Alexandria/University Town CenterDev - - 96,80596,805Sequence District by Alexandria/Sorrento MesaDev/Redev - - 555,754555,754410 West Harrison Street/Elliott BayDev - - 17,20517,205Other/SeattleDev - - 63,05763,057CanadaRedev - - 247,743247,743 - - 1,815,0841,815,084Total52,620 - 1,815,0841,867,704 development and redevelopment projects by more than $300 million over the next few •In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon insurance, utilities, repairs and maintenance, common area expenses, and other operating expenses 4Q25 Dispositions SIGNIFICANTLIQUIDITYPERCENTAGE OF FIXED-RATE DEBT SINCE 2021(1)$5.3B96.7%REMAINING DEBT TERM(IN YEARS)DEBT INTEREST RATE12.13.91%Longest Among S&P 500 REITs(3) Life Science Product, Service, and Device Equity Research Coverage Adjusted EBITDA margin: properties owned by our consolidated and unconsolidated real estate joint ventures. For operating from operations is helpful to investors as an additional measure of the performance of an equity order to provide results that are more closely related to the results of operations of our properties. For 100% of the RSF of our consolidated properties and our share of the RSF of properties held in higher annual rental rates compared to other classes of similar properties. AAA locations are in close represent our initial estimates at the commencement of the project. We expect to update this information The following table reconciles interest expense, the most directly comparable financial 2019 - 2025AGGREGATE$11BTotal Sales(1)$3.9BTotal Gains onSales of Real Estate(2)$2.8BTotal Impairmentsof Real Estate(2) Three Months Ended December 31,Year Ended December 31,20252024$ Change% Change20252024$ Change% ChangeIncome from rentals:Same properties$425,975$451,251$(25,276)(5.6)%$1,687,734$1,732,019$(44,285)(2.6)%Non-same properties112,355115,284(2,929)(2.5)497,155572,320(75,165)(13.1)Rental revenues538,330566,535(28,205)(5.0)2,184,8892,304,339(119,450)(5.2)Same properties163,222160,9842,2381.4627,224594,47132,7535.5Non-same properties27,32035,730(8,410)(23.5)133,062150,896(17,834)(11.8)Tenant recoveries190,542196,714(6,172)(3.1)760,286745,36714,9192.0Income from rentals728,872763,249(34,377)(4.5)2,945,1753,049,706(104,531)(3.4)Same properties793335458136.71,7911,26752441.4Non-same properties24,74925,361(612)(2.4)79,59065,42114,16921.7Other income25,54225,696(154)(0.6)81,38166,68814,69322.0Same properties589,990612,570(22,580)(3.7)2,316,7492,327,757(11,008)(0.5)Non-same properties164,424176,375(11,951)(6.8)709,807788,637(78,830)(10.0)Total revenues754,414788,945(34,531)(4.4)3,026,5563,116,394(89,838)(2.9)Same properties195,291192,7682,5231.3752,481706,90445,5776.4Non-same properties37,25247,664(10,412)(21.8)170,124202,361(32,237)(15.9)Rental operations232,543240,432(7,889)(3.3)922,605909,26513,3401.5Same properties394,699419,802(25,103)(6.0)1,564,2681,620,853(56,585)(3.5)Non-same properties127,172128,711(1,539)(1.2)539,683586,276(46,593)(7.9)Net operating income$521,871$548,513$(26,642)(4.9)%(2)$2,103,951$2,207,129$(103,178)(4.7)%(2)Net operating income - same properties$394,699$419,802$(25,103)(6.0)%$1,564,268$1,620,853$(56,585)(3.5)%Straight-line rent revenue (5,296)(21,637)16,341(75.5)(25,078)(94,232)69,154(73.4)Amortization of acquired below-market leases and deferred revenue related to tenant-funded and -built landlord improvements(9,503)(11,504)2,001(17.4)(36,763)(37,512)749(2.0)Net operating income - same properties (cash basis)$379,900$386,661$(6,761)(1.7)%$1,502,427$1,489,109$13,3180.9% resulting from the volatility of market conditions outside of our control. For example, we exclude gains or Key highlightsYTDOperating results4Q254Q2420252024Net (loss) income attributable to Alexandria’s common stockholders - diluted:In millions$(1,081.8)$(64.9)$(1,438.0)$309.6Per share$(6.35)$(0.38)$(8.44)$1.80Funds from operations attributable to Alexandria’s common stockholders - diluted, as adjusted:In millions$368.5$411.8$1,534.7$1,629.1Per share$2.16$2.39$9.01$9.47 For any questions, please contact corporateinformation@are.com; Joel S. Marcus, executive chairman and founder; Peter M. Moglia, chief executive officer and chief investment officer; Marc E. Binda, noncontrolling interest share of each component presented; and (ii) for each real estate joint venture that operating trends. tenant base. years. maturity. No gain or loss was incurred in connection with this repayment. ONSHORING PHARMA SUPPLY CHAINS & ACCELERATING ACCESS TO TRANSFORMATIVE THERAPIES Stabilized Properties and earned in the period during which the applicable expenses are incurred and the tenant’s obligation •We completed $1.47 billion of dispositions during 4Q25. These dispositions had annual net operating income of $118 million (based on consolidated 3Q25 annualized results) with a The following table reconciles debt to net debt and preferred stock and computes the ratio to REIT. Moreover, we believe that funds from operations, as adjusted, allows investors to compare our metrics based on annual rental revenue, refer to the definition of annual rental revenue herein. The following table summarizes unencumbered net operating income as a percentage of total example, interest expense is not necessarily linked to the operating performance of a real estate asset Multinational Pharmaceutical Land unconsolidated real estate joint ventures. As of December 31, 2025, approximately 92% of our leases proximity to concentrations of specialized skills, knowledge, institutions, and related businesses. It is upon completion of the project, or sooner if there are significant changes to the expected project yields The weighted-average shares of common stock outstanding used in calculating EPS - diluted, measure calculated and presented in accordance with GAAP, to cash interest and computes fixed- losses on the early extinguishment of debt to allow investors to measure our performance independent chief financial officer and treasurer; or Paula Schwartz, managing director of Rx Communications Group, at (917) 633-7790. As of December 31, 2025, Alexandria has a total market capitalization of Dividend payout ratio (common stock) we do not control and do not consolidate, which are instead controlled jointly or by our joint venture 4Q252025Lease renewals and re-leasing of space:Rental rate changes(9.9)%7.0%Rental rate changes (cash basis)(5.2)%3.5%RSF821,2892,543,473Leasing of previously vacant space - RSF393,376944,362Leasing of development and redevelopment space - RSF6,279704,821Total leasing activity - RSF1,220,9444,192,656 Three Months Ended(Dollars in thousands)12/31/259/30/256/30/253/31/2512/31/24Net (loss) income$(995,354)$(197,845)$(62,189)$38,662$(16,095)Interest expense65,67454,85255,29650,87655,659Income taxes1,8513,7371,0201,1451,855Depreciation and amortization322,063340,230346,123342,062330,108Stock compensation expense8,23210,29312,53010,06412,477Loss on early extinguishment of debt - 107 - - - Gain on sales of real estate(619,914)(9,366) - (13,165)(101,806)Unrealized (gains) losses on non-real estate investments(98,548)(18,515)21,93868,14579,776Significant realized losses on non-real estate investments103,329 - - - - Impairment of real estate1,717,188323,870129,60632,154186,564Impairment of non-real estate investments20,18125,13939,21611,18020,266Increase (decrease) in provision for expected credit losses on financial instruments(341) - - 285(434)Adjusted EBITDA$524,361$532,502$543,540$541,408$568,370Total revenues$754,414$751,944$762,040$758,158$788,945Adjusted EBITDA margin70%71%71%71%72% •3% reduction in non-income-producing assets to 17% as a percentage of gross assets. Alexandria is currently covered by the following research analysts. This list may be incomplete and is subject to change as firms initiate or discontinue coverage of our company. Please note that any opinions, estimates, or forecasts regarding our historical or predicted performance made by these analysts are theirs alone and do not represent opinions, estimates, or forecasts of Alexandria or our management. Alexandria does not by our reference or distribution of the information below imply our endorsement of or concurrence with any opinions, estimates, or forecasts of these analysts. Interested persons may obtain copies of analysts’ reports on their own as we do not distribute these reports. Several of these firms may, from time to time, own our stock and/or hold other long or short positions in our stock and may provide compensated services to us. to reimburse us arises. performance to the performance of other real estate companies on a consistent basis, without having to weighted-average disposition date of December 9, 2025. Refer to “2025 Dispositions and sales of partial interests” in the Earnings Press Release for additional details. Adjusted EBITDA: net operating income: and is often incurred at the corporate level rather than at the property level. In addition, depreciation and (on an annual rental revenue basis) were triple net leases, which require tenants to pay substantially all important to note that our definition of property classification may not be directly comparable to other or costs. FFO per share - diluted, and FFO per share - diluted, as adjusted, during each period are calculated as Investments charge coverage ratio: of our indebtedness and capital structure. We believe that adjusting for the effects of impairments and partners through contractual rights or majority voting rights, we apply our economic ownership The following table reconciles our annual rental revenue and development and redevelopment $20.75 billion and an asset base in North America that includes 35.9 million RSF of •We are evaluating business strategy for four additional projects. account for differences recognized because of real estate acquisition and disposition decisions, Same property comparisons Three Months Ended(Dollars in thousands)12/31/259/30/256/30/253/31/2512/31/24Unencumbered net operating income$521,871$512,710$535,766$530,691$547,921Encumbered net operating income - - 1,8411,072592Total net operating income$521,871$512,710$537,607$531,763$548,513Unencumbered net operating income as a percentage of total net operating income100.0%100.0%99.7%99.8%99.9% Key Sources and Uses of CapitalRangeMidpointSources of capital:Reduction in debt(5)$(1,075)$(2,275)$(1,675)Net cash provided by operating activities after dividends475575525Dispositions and sales of partial interests (refer to page 6)(6) 2,1003,7002,900Total sources of capital$1,500$2,000$1,750Uses of capital:Construction$1,500$2,000$1,750Total uses of capital$1,500$2,000$1,750Reduction in debt (included above):Repayment of unsecured notes payable with 2026 maturities(7)$(650)$(650)$(650)Unsecured senior line of credit, commercial paper, and other(425)(1,625)(1,025)Reduction in debt$(1,075)$(2,275)$(1,675) amortization, because of historical cost accounting and useful life estimates, may distort comparability of The following table presents our new Class A/A+ development and redevelopment pipeline, real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other equity REITs. Dividend payout ratio (common stock) is the ratio of the absolute dollar amount of dividends follows. Also shown are the weighted-average unvested shares associated with unvested RSAs with gains or losses on sales of real estate, significant impairments and realized gains or losses on non-real About the Company percentage to each financial item to arrive at our proportionate share of each component presented. pipeline RSF, excluding properties classified as held for sale, as of December 31, 2025: operating properties and 3.5 million RSF of Class A/A+ properties undergoing construction. •As of December 31, 2025: (Dollars in thousands)12/31/259/30/256/30/253/31/2512/31/24Secured notes payable$ - $ - $153,500$150,807$149,909Unsecured senior notes payable 12,047,39412,044,99912,042,60712,640,14412,094,465Unsecured senior line of credit and commercial paper353,1611,548,5421,097,993299,883 - Unamortized deferred financing costs74,31476,38378,57480,77677,649Cash and cash equivalents(549,062)(579,474)(520,545)(476,430)(552,146)Restricted cash(4,693)(4,705)(7,403)(7,324)(7,701)Preferred stock - - - - - Net debt and preferred stock$11,921,114$13,085,745$12,844,726$12,687,856$11,762,176Adjusted EBITDA: - quarter annualized$2,097,444$2,130,008$2,174,160$2,165,632$2,273,480 - trailing 12 months$2,141,811$2,185,820$2,208,226$2,218,722$2,228,921Net debt and preferred stock to Adjusted EBITDA: - quarter annualized5.7x6.1x5.9x5.9x5.2x - trailing 12 months5.6x6.0x5.8x5.7x5.3x Market2026 Contractual Lease Expirations (in RSF)Annual Rental Revenue(per RSF)(1)2027 Contractual Lease Expirations (in RSF)Annual Rental Revenue(per RSF)(1)LeasedNegotiating/AnticipatingTargeted for Future Development/RedevelopmentRemainingExpiringLeasesTotal(2)LeasedNegotiating/AnticipatingTargeted for FutureDevelopment/RedevelopmentRemainingExpiring LeasesTotalGreater Boston144,451 - - 248,627393,078$44.0150,649 - - 179,430230,079$94.88San Francisco Bay Area6,52722,000 - 286,652315,17969.981,873 - - 215,684217,55770.96San Diego - 49,79152,620(3)153,477255,88854.62 - - - 339,716339,71643.71Seattle32,500 - - 150,145182,64528.004,32025,898 - 486,950517,16843.59Maryland171,239 - - 173,729344,96829.48 - - - 261,550261,55027.38Research Triangle42,3186,439 - 99,209147,96643.6634,910 - - 242,303277,21334.74New York City35,256 - - 39,65974,91571.65 - - - 98,29998,29991.95Texas - - - - - - - - - 91,71191,71126.10Non-cluster/other markets - - - 24,56724,56759.21 - - - 11,41811,418N/ASubtotal432,29178,23052,6201,176,0651,739,20647.1191,75225,898 - 1,927,0612,044,71150.43Key lease expirations with expected downtime140,9869,836 - 1,010,637(4)1,161,459(4)61.14 - - - 1,176,1231,176,123(5)61.61Total573,27788,06652,6202,186,7022,900,665$52.7391,75225,898 - 3,103,1843,220,834$54.52Percentage of expiring leases20%3%2%75%100%3%1%0%96%100% •Initial stabilized yield reflects rental income, including contractual rent escalations and any rent We classify rental revenues and tenant recoveries generated through the leasing of real (3.5)% financing decisions, capital structure, capital market transactions, variances resulting from the volatility Three Months Ended(Dollars in thousands)12/31/259/30/256/30/253/31/2512/31/24Adjusted EBITDA$524,361$532,502$543,540$541,408$568,370Interest expense$65,674$54,852$55,296$50,876$55,659Capitalized interest81,84586,09182,42380,06581,586Amortization of loan fees(4,481)(4,505)(4,615)(4,691)(4,620)Amortization of debt discounts(327)(325)(335)(349)(333)Cash interest and fixed charges$142,711$136,113$132,769$125,901$132,292Fixed-charge coverage ratio: - quarter annualized3.7x3.9x4.1x4.3x4.3x - trailing 12 months4.0x4.1x4.3x4.4x4.5x operating performance at the property level. Impairments of real estate have been excluded in deriving 2026 key lease expirations with expected downtime excluding properties held for sale, as a percentage of gross assets and as a percentage of annual rental operating expenses (including increases thereto) in addition to base rent. Annual rental revenue on our common stock (shares of common stock outstanding on the respective record dates multiplied by nonforfeitable dividends used in calculating amounts allocable to these awards pursuant to the two-class SIGNIFICANTLIQUIDITYPERCENTAGE OF FIXED-RATE DEBT SINCE 2021(1)$5.3B96.7%REMAINING DEBT TERM(IN YEARS)DEBT INTEREST RATE12.13.91%Longest Among S&P 500 REITs(3) 5.9 Years Average Debt Term of S&P 500 REITs as of September 30, 2025 estate investments, changes in provision for expected credit losses on financial instruments, and Alexandria’s development and redevelopment pipeline delivered incremental annual net operating Key AssumptionsLowHighOccupancy percentage in North America as of December 31, 2026(2)87.7%89.3%Lease renewals and re-leasing of space:Rental rate changes(2.0)%6.0%Rental rate changes (cash basis)(12.0)%(4.0)%Same property performance:Net operating income(9.5)%(7.5)%Net operating income (cash basis)(9.5)%(7.5)%Straight-line rent revenue$65$95General and administrative expenses$134$154Capitalization of interest(3)$225$275Interest expense$230$280Realized gains on non-real estate investments(4)$60$90 •Our non-real estate investments aggregated $1.50 billion. As a result of changes within our total property portfolio during the comparative periods →→AstraZeneca’s new Gaithersburg facility aims to accelerate the production of innovative medicines for cancer, rare, and chronic diseasesThe investment builds upon AstraZeneca’s $300M investment in a cell therapy manufacturing facility at 9950 Medical Center Drive on the Alexandria Center® for Life Science - Shady Grove Megacampus™ →→AstraZeneca’s announced $2B(1) investment in Maryland includes substantial support for mission-critical manufacturing at 700 Quince Orchard RoadAstraZeneca has committed to invest $50B(2) in U.S.-based manufacturing and R&D by 2030 ACHIEVED4Q25 LEVERAGE(2)5.7x concessions over the term(s) of the lease(s), calculated on a straight-line basis, and any estate assets within revenues in income from rentals in our consolidated statements of operations. We of market conditions outside of our control, or other corporate activities that may not be representative of Alexandria Real Estate Equities, Inc. (NYSE: ARE), an S&P 500® company, is a best-in-class, mission-driven life science REIT making a positive and lasting impact on the world. With our founding in 1994, The components of balance sheet and operating results information related to our real estate Credit ratings net operating income because we do not consider impairments of real estate to be property-level revenue as of December 31, 2025: •There are key lease expirations primarily in our Greater Boston, San Francisco Bay Area, and San Diego markets, aggregating 1.2 million RSF, with a weighted‑average lease excludes these operating expenses recovered from our tenants. Amounts recovered from our tenants the related dividend per share) to funds from operations attributable to Alexandria’s common Placed Into ServiceNear-Term DeliveriesIntermediate-Term DeliveriesEvaluating Business Strategy202520262027 - 20282026-2028$78M$97M$123M$113M97% Occupied86%Leased/Negotiating51%Leased/Negotiating8%Leased/Negotiating852,764 RSF699,933 RSF1.6 million RSF1.2 million RSF $76MProjected CumulativeG&A Savingsin 2025 and 2026Compared to 2024(1) method for each of the respective periods presented below. significant termination fees allows investors to evaluate performance from period to period on a (Dollars in thousands)Annual Rental RevenueDevelopment and Redevelopment Pipeline RSFMegacampus$1,451,39116,735,429Core and non-core410,6654,867,151Total$1,862,05621,602,580Megacampus as a percentage of annual rental revenue and of total development and redevelopment pipeline RSF78%77% (1)All covenant ratio titles utilize terms as defined in the respective debt and credit agreements. The calculation of consolidated EBITDA is based on the definitions contained in our loan agreements and is not directly comparable to (1)Represents the weighted-average interest rate as of the end of the applicable period, including expense/income related to the amortization of loan fees, amortization of debt premiums (discounts), and other bank fees. income of $10 million commencing during 4Q25, with an additional $97 million of incremental Alexandria has a long-standing and proven track record of developing Class A/A+ presented, including changes from assets acquired or sold, properties placed into development or •Unrealized gains presented in our consolidated balance sheet were $133.4 million, amortization of deferred revenue related to tenant-funded and tenant-built landlord improvements. provide investors with a separate presentation of rental revenues and tenant recoveries in “Same the operating performance of our properties. Alexandria pioneered the life science real estate niche. Alexandria is the preeminent and longest-tenured owner, operator, and developer of collaborative Megacampus™ ecosystems in AAA life science innovation joint ventures do not represent our legal claim to those items. For each entity that we do not wholly own, Maintain Optionality forFuture Growth Focused onMegacampus™ Investment operating expenses. Impairments of real estate relate to changes in the values of our assets and do not December 31, 2025December 31, 2024InvestmentsCostUnrealized GainsUnrealized LossesCarrying AmountCarrying AmountPublicly traded companies$54,752$44,319$(4,143)$94,928$105,667Entities that report NAV460,16089,514(37,298)512,376609,866Entities that do not report NAV:Entities with observable price changes82,25250,601(9,615)123,238174,737Entities without observable price changes413,324 - - 413,324400,487Investments accounted for under the equity method N/AN/AN/A357,383186,228December 31, 2025$1,010,488(6)$184,434$(51,056)$1,501,249$1,476,985December 31, 2024$1,207,146$228,100$(144,489)$1,476,985 related to these operating expenses, along with base rent, are classified in income from rentals in our stockholders - diluted, as adjusted. expiration date in April 2026 and annual rental revenue of $71 million. These leases are expected to become vacant upon expiration, and we anticipate downtime on these spaces to Percentage of(Dollars in thousands)Book ValueGross AssetsAnnual Rental RevenueProjects under active construction$3,181,0128% - %Future development projects(1) and land parcels primarily located in Megacampuses3,607,45291Total Class A/A+ development and redevelopment pipeline, excluding properties held for sale6,788,464171Properties held for sale - land parcels261,2081 - Total Class A/A+ development and redevelopment pipeline$7,049,67218%1% consistent basis without having to account for differences recognized because of investing and financing the computation of EBITDA as described in Exchange Act Release No. 47226. (2)As of December 31, 2025, we had no outstanding balance on our unsecured senior line of credit. LARGEST, HIGHEST-QUALITYASSET BASE CLUSTERED IN THE KEY CENTERS OF LIFE SCIENCE INNOVATIONSECTOR-LEADING CLIENT TENANT BASEHIGH-QUALITY CASH FLOWSPROVEN UNDERWRITINGFORTRESS BALANCE SHEETLONG-TENURED, HIGHLY EXPERIENCED MANAGEMENT TEAM annual net operating income anticipated to deliver by 4Q26 primarily from projects that are 86% redevelopment, and development or redevelopment properties recently placed into service, the properties clustered in highly dynamic and collaborative Megacampus environments that comprising gross unrealized gains and losses aggregating $184.4 million and $51.1 million, •Initial stabilized yield (cash basis) reflects cash rents at the stabilization date after initial rental property performance” in this Supplemental Information because we believe it promotes investors’ Three Months EndedYear Ended(In thousands)12/31/259/30/256/30/253/31/2512/31/2412/31/2512/31/24Basic shares for earnings per share170,394170,181170,135170,522172,262170,307172,071Unvested RSAs with forfeitable dividends - - - - - - - Diluted shares for earnings per share170,394170,181170,135170,522172,262170,307172,071Basic shares for funds from operations per share and funds from operations per share, as adjusted170,394170,181170,135170,522172,262170,307172,071Unvested RSAs with forfeitable dividends1101245777 - 83 - Diluted shares for funds from operations per share and funds from operations per share, as adjusted170,504170,305170,192170,599172,262170,390172,071Weighted-average unvested RSAs with nonforfeitable dividends used in calculating the allocations of net income, funds from operations, and funds from operations, as adjusted1,5701,9171,9982,0532,4171,8832,779 cluster locations, including Greater Boston, the San Francisco Bay Area, San Diego, Seattle, Maryland, Research Triangle, and New York City. As of December 31, 2025, Alexandria has a total market capitalization the joint venture agreement generally determines what equity holders can receive upon capital events, Represents the credit ratings assigned by S&P Global Ratings or Moody’s Ratings as of reflect the current operating performance with respect to related revenues or expenses. Our consolidated statements of operations. (3)The commercial paper program provides us with the ability to issue up to $2.50 billion of commercial paper notes that bear interest at short-term fixed rates and can generally be issued with a maturity of 30 days or less and with range from 6 to 24 months on a weighted‑average basis. 150,822 RSF has been leased or is under negotiations and we have identified prospective tenants or have early negotiations decisions related to our real estate and non-real estate investments or other corporate activities that SubmarketAs of 3Q25PropertyCIP RSFTotal ProjectLeased/NegotiatingProject Status as of 4Q25Projects under construction as of 3Q254,239,76243%Redevelopment projects removed from pipeline in 4Q25:651 Gateway BoulevardSouth San Francisco(237,684)21%Sold in 4Q25CanadaCanada(56,314)78Held for sale as of 4Q25One Hampshire StreetCambridge(104,956) - Held for sale as of 4Q25401 Park DriveFenway(137,675) - Reclassified to operating(1)(536,629)32Projects placed into service in 4Q25(139,979)100Projects under construction as of 4Q253,563,15446% BMOCFRAGreen StreetRBC Capital MarketsJohn Kim / Juan SanabriaNathan SchmidtDylan BurzinskiMichael Carroll(212) 885-4115 / (312) 845-4074(646) 517-1144(949) 640-8780(440) 715-2649BNP Paribas ExaneCitigroup Global Markets Inc.J.P. Morgan Securities LLCRobert W. Baird & Co. IncorporatedNate Crossett / Monir KoummalNicholas Joseph / Seth BergeyAnthony Paolone / Ray ZhongWesley Golladay / Nicholas Thillman(646) 342-1588 / (646) 342-1554(212) 816-1909 / (212) 816-2066(212) 622-6682 / (212) 622-5411(216) 737-7510 / (414) 298-5053BofA SecuritiesCitizensJefferiesFarrell Granath / Jeff SpectorAaron Hecht / Linda FuJoe Dickstein / Katie Elders(646) 855-1351 / (646) 855-1363(415) 835-3963 / (415) 869-4411(212) 778-8771 / (917) 421-1968BTIG, LLCDeutsche Bank AGMizuho Securities USA LLCTom Catherwood / Michael TompkinsTayo Okusanya / Samuel OhiomahVikram Malhotra / Jyoti Yadav(212) 738-6140 / (212) 527-3566(212) 250-9284 / (212) 250-0057(212) 282-3827 / (212) 471-2683Cantor FitzgeraldEvercore ISIMorgan Stanley & Co. LLCRichard Anderson / Jeffrey CarrSteve Sakwa / James KammertRonald Kamdem / Derrick Metzler(929) 441-6927 / (929) 709-0434(212) 446-9462 / (312) 705-4233(212) 296-8319 / (212) 761-3366Fixed Income Research CoverageRating AgenciesBarclays Capital Inc.J.P. Morgan Securities LLCMoody’s Ratings S&P Global RatingsSrinjoy Banerjee / Ishaan PandyaMark Streeter / Tyler Schachner(212) 553-0376 Michael Souers(212) 526-3521 / (212) 526-2970(212) 834-5086 / (212) 834-2238 (212) 438-2508CreditSightsMizuho Securities USA LLCNicholas MogliaThierry Perrein(212) 340-3886(212) 205-7665 leased/negotiating consolidated total income from rentals, as well as rental operating expenses in our operating results, can The 2018 White Paper published by the Nareit Board of Governors (the “Nareit White Paper”) enhance our tenants’ ability to successfully recruit and retain world-class talent and inspire concessions, if any, have elapsed and our total cash investment in the property. understanding of our operating results. We believe that the presentation of tenant recoveries is useful to respectively. 5.6%11.3%Alexandria4Q25(2)S&P 500 REITAverage 2023 - 3Q25(Excluding Alexandria)(3) of $20.75 billion and an asset base in North America that includes 35.9 million RSF of operating properties and 3.5 million RSF of Class A/A+ properties undergoing construction. Alexandria has a long-standing and such as sales or refinancing, or in the event of a liquidation. Equity holders are normally entitled to their December 31, 2025. A credit rating is not a recommendation to buy, sell, or hold securities and may be impairments of real estate represent the write-down in the value of the assets to the estimated fair value a maximum maturity of 397 days from the date of issuance. Borrowings under the program are used to fund short-term capital needs and are back-stopped by our unsecured senior line of credit. In the event we are unable to Dividend yield may not be representative of the operating performance of our properties. for another 468,470 RSF. We expect a decline in net operating income of approximately $14 million for the three months ending March 31, 2026, compared to the three months ended show significant changes from period to period. In order to supplement an evaluation of our results of defines funds from operations as net income (computed in accordance with GAAP), excluding gains or investors as a supplemental measure of our ability to recover operating expenses under our triple net Public Biotechnology - Approved or Marketed productivity, efficiency, creativity, and success. •Investment loss of $3.9 million for 4Q25 presented in our consolidated statement of issue commercial paper notes or refinance outstanding borrowings under terms equal to or more favorable than those under our unsecured senior line of credit, we expect to borrow under the unsecured senior line of credit at Unconsolidated real estate joint ventures’ debtAt 100%Unconsolidated Joint VentureMaturity DateStated RateInterest Rate(1)Aggregate CommitmentDebt Balance(2)Our Share101 West Dickman Street10/29/26SOFR+1.95%(3)5.74%$26,750$19,13658.4%1655 and 1725 Third Street2/10/356.37%6.44%500,000496,88110.0%$526,750$516,017 •During 4Q25, we placed into service one development project aggregating 139,979 RSF that proven track record of developing Class A/A+ properties clustered in highly dynamic and collaborative Megacampus environments that enhance our tenants’ ability to successfully recruit and retain world-class talent respective legal ownership of any residual cash from a joint venture only after all liabilities, priority Noncontrolling Interest Share of Consolidated Real Estate JVsOur Share of Unconsolidated Real Estate JVsDecember 31, 2025December 31, 2025Three Months EndedYear EndedThree Months EndedYear EndedTotal revenues$114,339$467,580$2,656$10,619Rental operations(36,231)(145,209)(1,040)(4,048)78,108322,3711,6166,571General and administrative(823)(3,016)(32)(133)Interest(62)(967)(1,058)(4,176)Depreciation and amortization of real estate assets(39,942)(154,727)(855)(3,703)Impairment of real estate(265,266)(1)(265,266) - (8,673)Gain on sale of real estate of consolidated JV312,807(2)312,807 - - Gain on sale of interest of unconsolidated JV - - 25483Fixed returns allocated to redeemable noncontrolling interests(3)6991,642 - - $85,521$212,844$(304)$(9,631)Straight-line rent and below-market lease revenue $2,723$19,580$139$645Funds from operations(4)$77,922$320,030$526$2,262 subject to revision or withdrawal at any time. less cost to sell. These impairments result from investing decisions or a deterioration in market Capitalization rates ACHIEVED4Q25 LEVERAGE(2)5.7x December 31, 2025, related to the portion of these leases that are scheduled to expire in 1Q26, which includes operating expenses that will not be recoverable once the spaces (1)Refer to “Guidance” in the Earnings Press Release for key considerations on 1Q26 guidance. losses on sales of real estate, and impairments of real estate, plus depreciation and amortization of Other(1) Under construction - evaluating business strategy - $878.7 million operations over a given quarterly or annual period, we analyze the operating performance for all leases, including recoveries of utilities, repairs and maintenance, insurance, property taxes, common Investment-grade or publicly traded large cap tenants SOFR+0.855%. As of December 31, 2025, we had $353.2 million of commercial paper notes outstanding. Dividend strategy to share net cash flows from operating activities with stockholders while Dividend yield for the quarter represents the annualized quarter dividend divided by the operations consisted of $21.1 million of realized gains, $103.3 million from a significant and inspire productivity, efficiency, creativity, and success. Alexandria also provides strategic capital to transformative life science companies through our venture capital platform. We believe our unique business distributions, and claims have been repaid or satisfied. is 100% occupied at 10075 Barnes Canyon Road in our Sorrento Mesa submarket and conditions. We also exclude realized and unrealized investment gain or loss, which results from 20242025 Repositioning and smaller redevelopment projects(1) - $1.19 billion Reduce Capital Spendand Funding Needs A best-in-class REIT with a high-quality, diverse tenant base, strong margins, and long lease In addition, we believe that excluding charges related to stock compensation and unrealized (2)Represents temporary vacancies as of December 31, 2025 aggregating 899,259 RSF, primarily in the Greater SUPPLEMENTAL become vacant. Refer to “Contractual lease expirations” in the Supplemental Information for additional details. operating real estate assets, and after adjustments for our share of consolidated and unconsolidated consolidated properties that were fully operating for the entirety of the comparative periods presented, (4)We calculate the weighted-average remaining term of our commercial paper notes by using the maturity date of our unsecured senior line of credit. Using the maturity date of our outstanding commercial paper notes, the area expenses, and other operating expenses, and of our ability to mitigate the effect to net income for retaining a significant portion for reinvestment Capitalization rates are calculated based on net operating income and net operating income closing common stock price at the end of the quarter. Alexandria also provides strategic capital to transformative life science Development, redevelopment, and pre-construction model and diligent underwriting ensure a high-quality and diverse tenant base that results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. For realized loss on one transaction, $98.5 million of unrealized gains, and $20.2 million of investment decisions that occur at the corporate level related to non-real estate investments in publicly delivered incremental annual net operating income of $10 million. Boston, San Francisco Bay Area, and Seattle markets, that are leased and expected to be occupied upon gains or losses facilitates for investors a comparison of our business activities across periods without the terms partnerships and real estate joint ventures. Impairments represent the write-down of assets when fair Investment-grade or publicly traded large cap tenants represent tenants that are investment- consolidated weighted-average maturity of our debt is 12.0 years. The commercial paper notes sold during the year ended December 31, 2025 were issued at a weighted-average yield to maturity of 4.48% and had a weighted- Summary of occupancy We believe that this information can help investors estimate the balance sheet and operating referred to as same properties. We separately present quarterly and year-to-date same property results Refer to “Megacampus™” under “Definitions and reconciliations” in the Supplemental Information for additional details. any significant variability to components of our operating expenses. (cash basis) annualized, excluding lease termination fees, on stabilized operating assets for the quarter 12% 17% more information on Alexandria, please visit www.are.com. companies through our venture capital platform. We believe our unique business model traded companies and certain privately held entities. Therefore, we do not consider these activities to be completion of building and/or tenant improvements. The weighted-average expected delivery date is impairment charges. •Common stock dividend declared of $0.72 per share for 4Q25, representing a 45% reduction •Annual net operating income (cash basis) from recently delivered projects is expected to volatility resulting from market forces outside of our control. Adjusted EBITDA has limitations as a Projected capital contributions from partners in consolidated real estate joint ventures to fund constructionTimingAmount(5)2026$100,0002027 and beyond37,000Total$137,000 average maturity term of 19 days. value over the recoverability period is less than the carrying value due to changes in general market Certain items included in 4Q25 results not expected to reoccur in 1Q26 grade rated or publicly traded companies with an average daily market capitalization greater than $10 results information related to our partially owned entities. Presenting this information provides a to align with the interim financial information required by the SEC in our management’s discussion and Operating PropertiesOperating and Redevelopment PropertiesMarket12/31/259/30/2512/31/2412/31/259/30/2512/31/24Greater Boston86.4%86.8%94.8%75.1%73.6%80.8%San Francisco Bay Area90.990.493.389.486.489.1San Diego97.295.296.397.295.296.3Seattle88.4(2)90.192.488.490.192.4Maryland93.693.995.793.693.995.7Research Triangle95.294.997.495.294.997.4New York City96.498.388.496.498.388.4Texas79.979.995.576.576.591.8Subtotal90.990.894.886.985.990.0CanadaN/A(3)90.395.9N/A85.482.9Non-cluster/other markets91.2(1)69.672.591.269.672.5North America90.9%(4)90.6%94.6%86.9%85.8%89.7% A key component of our business model is our disciplined allocation of capital to the (As of December 31, 2025, unless stated otherwise)Occupancy of operating properties in North America90.9%Percentage of annual rental revenue in effect from Megacampus™ platform78%Percentage of annual rental revenue in effect from investment-grade or publicly traded large cap tenants53%Operating margin69%Adjusted EBITDA margin70%Percentage of leases containing annual rent escalations97%Weighted-average remaining lease term:Top 20 tenants9.7yearsAll tenants7.5yearsStrong 4Q25 tenant collections:4Q25 tenant rents and receivables collected as of January 26, 202699.9% Weighted-average interest rate for capitalization of interest preceding the date on which the property is sold, or near-term prospective net operating income. approximately August 2026 and the expected annual rental revenue is approximately $52 million. Space Intentionally Blank and diligent underwriting ensure a high-quality and diverse tenant base that results in an indication of operating performance of our real estate assets at the property level. Our calculation of from the quarterly dividend declared of $1.32 for 3Q25. increase by $26 million upon the burn-off of initial free rent, which has a weighted-average Advanced Technologies(2) Life Science Product, Service, and Device measure of our performance. Adjusted EBITDA does not reflect our historical expenditures or future INFORMATION conditions and do not necessarily reflect the operating performance of the properties during the (1)Total square footage includes 1.9 million RSF of buildings currently in operation that we expect to demolish or redevelop and commence future construction subject to market conditions and leasing. Refer to “Investments in real estate” billion for the twelve months ended December 31, 2025, as reported by Bloomberg Professional
- During 4Q25, we terminated a lease at one property in our South San Francisco submarket aggregating 170,618 RSF, which had generated annual rental revenue of $11.4 million, perspective not immediately available from consolidated financial statements and one that can analysis of our financial condition and results of operations. These same properties are analyzed development and redevelopment of new Class A/A+ properties, as well as property enhancements The following table reconciles income from rentals to tenant recoveries: net operating income also excludes charges incurred from changes in certain financing decisions, such Life Science Product, Service, and Device higher occupancy levels, longer lease terms, higher rental income, higher returns, and •The decision to reduce the declared dividend per common share reflects our commitment to requirements for capital expenditures or contractual commitments. While Adjusted EBITDA is a relevant remaining period of approximately six months. Forward-Looking Statements under “Definitions and reconciliations” in the Supplemental Information for additional details, including development and redevelopment square feet currently included in rental properties. corresponding period. The weighted-average interest rate required for calculating capitalization of interest pursuant Key operating metrics Multinational Pharmaceutical Services. Credit ratings from Moody’s Ratings and S&P Global Ratings reflect credit ratings of the supplement an understanding of the joint venture assets, liabilities, revenues, and expenses included in separately from properties acquired subsequent to the first day in the earliest comparable quarterly or identified during the underwriting of certain acquired properties. These efforts are primarily concentrated ahead of its contractual lease expiration in early 2027. The termination allowed us to re-lease 100% of the space to a new tenant, with occupancy expected to commence in 2H26 Gross assets Capitalized interest Under construction - 2026 stabilization - $590.1 million (86% leased/negotiating) Consider Flexible and Opportunistic ShareBuyback Plan 269 East Grand Avenue4135 Campus Point CourtCampus Point by Alexandria10075 Barnes Canyon Road701 Dexter Avenue NorthSan Francisco Bay Area/South San FranciscoSan Diego/University Town CenterSan Diego/University Town CenterSan Diego/Sorrento MesaSeattle/Lake Union107,250 RSF426,927 RSF466,598 RSF81,610 RSF227,577 RSF - % Leased/Negotiating 100% Leased100% Leased68% Leased/Negotiating23% Leased/Negotiating as losses on early extinguishment of debt and changes in provision for expected credit losses on Average Debt OutstandingWeighted-Average Interest RateDecember 31, 2025December 31, 2025Three Months EndedYear EndedThree Months EndedYear EndedLong-term fixed-rate debt$12,121,545$12,248,0393.88%3.87%Short-term variable-rate unsecured senior line of credit and commercial paper program debt2,318,3581,281,1044.284.55Blended-average interest rate14,439,90313,529,1433.943.93Loan fee amortization and annual facility fee related to unsecured senior line of creditN/AN/A0.130.13Total/weighted average$14,439,903$13,529,1434.07%4.06% greater long-term asset value. For more information on Alexandria, please visit (2)Includes $3.18 billion of projects that are currently under construction. measure of performance, it does not represent net income (loss) or cash flows from operations maintaining the strength of our balance sheet, enhancing financial flexibility, and preserving •77% of the RSF in our total development and redevelopment pipeline is within our (1) (2) (3) Three Months EndedYear Ended(In thousands)12/31/259/30/256/30/253/31/2512/31/2412/31/2512/31/24Income from rentals$728,872$735,849$737,279$743,175$763,249$2,945,175$3,049,706Rental revenues(538,330)(541,070)(553,377)(552,112)(566,535)(2,184,889)(2,304,339)Tenant recoveries$190,542$194,779$183,902$191,063$196,714$760,286$745,367 to GAAP represents a weighted-average rate as of the end of the applicable period, based on the rates tenant’s parent entity, and there can be no assurance that a tenant’s parent entity will satisfy the tenant’s our consolidated results. year-to-date period presented, properties that underwent development or redevelopment at any time in collaborative Megacampus™ ecosystems within AAA life science innovation clusters, as well as other following the completion of tenant improvements. As a result of the termination, we recognized incremental rental revenue of $8.4 million during 4Q25, primarily from a termination Public Biotechnology We compute funds from operations, as adjusted, as funds from operations calculated in Operating metrics4Q252025(dollars in millions)Net operating income (cash basis) $1,985(1)$1,978(Decrease) Increase compared to 4Q24 and 2024(3.4)%(2)0.1%(2)Same property performance:Net operating income changes(6.0)%(3.5)%Net operating income changes (cash basis) (1.7)%0.9%Occupancy - current-period average91.0%92.5%Occupancy - same-period prior-year average95.5%95.2% This document includes “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. financial instruments, as these charges often relate to corporate strategy. Property operating expenses www.are.com. calculated and presented in accordance with GAAP, and it should not be considered as an alternative to liquidity of approximately $410 million on an annual basis, which will be used to support our Public Biotechnology - Preclinical or Clinical Stage applicable to borrowings outstanding during the period, including expense/income related to interest rate Megacampus ecosystems. Net cash provided by operating activities after dividends 230 Harriet Tubman Way10935, 10945, and 10955 Alexandria Way(2)10075 Barnes Canyon RoadSan Francisco Bay Area/South San FranciscoSan Diego/Torrey PinesSan Diego/Sorrento Mesa285,346 RSF334,996 RSF171,469 RSF100% Occupancy100% Occupancy100% Occupancy Gross assets are calculated as total assets plus accumulated depreciation: lease obligation upon such tenant’s default. We monitor the credit quality and related material changes during the comparative periods, unconsolidated real estate joint ventures, properties classified as held strategic locations that support innovation and growth. These projects are generally focused on Multinational Pharmaceutical Substantially CompleteLarge-Scale Non-CoreDisposition Plan fee, net of the deferred rent balances written off. We capitalize interest cost as a cost of a project during periods for which activities necessary accordance with the Nareit White Paper, excluding significant gains, losses, and impairments realized Such forward-looking statements include, without limitation, statements regarding our projected 2026 earnings per share, projected 2026 funds from operations per share, projected 2026 funds from operations per included in determining net operating income primarily consist of costs that are related to our operating those indicators in evaluating performance or liquidity. The components of balance sheet and operating results information related to our real estate 2026 capital plan. hedge agreements, amortization of loan fees, amortization of debt premiums (discounts), and other bank (1)Includes interest expense and amortization of loan fees. of our tenants. Material changes that cause a tenant’s market capitalization to decrease below $10 for sale, and corporate entities (legal entities performing general and administrative functions), which are providing high-quality, generic, and reusable spaces that meet the real estate requirements of a wide Government Institutions Development and Redevelopment ProjectsIncremental Annual Net Operating IncomeRSFLeased/NegotiatingPercentage(dollars in millions)Expected to be placed into service:2026$97(1)699,933(2)86%(3)2027- 20281231,614,99451%$220Projects under business strategy evaluation:2026-2028$1131,248,2278% (In thousands)12/31/259/30/256/30/253/31/2512/31/24Total assets$34,081,835$37,375,148$37,623,629$37,600,428$37,527,449Accumulated depreciation6,127,5256,416,7456,146,3785,886,5615,625,179Gross assets$40,209,360$43,791,893$43,770,007$43,486,989$43,152,628 to develop, redevelop, or reposition a project for its intended use are ongoing, provided that on non-real estate investments, unrealized gains or losses on non-real estate investments, impairments share, as adjusted, projected net operating income, and our projected sources and uses of capital. You can identify the forward-looking statements by their use of forward-looking words, such as “forecast,” properties, such as utilities, repairs, and maintenance; rental expense related to ground leases; Net cash provided by operating activities after dividends is reduced by distributions to (1)Includes projects with existing buildings that are generating or can generate operating cash flows. Also includes Future projects with critical milestones in 2026 - Megacampus projects(2) - $2.08 billion joint ventures are limited as an analytical tool as the overall economic ownership interest does not Tenant base (2)Represents outstanding principal, net of unamortized deferred financing costs, as of December 31, 2025. fees. A separate calculation is performed to determine our weighted-average interest rate for •Significant net cash flows provided by operating activities after dividends retained for billion, which are not immediately reflected in the twelve-month average, may result in their exclusion excluded from same property results. Additionally, termination fees, if any, are excluded from the results range of tenants. Upon completion, each development or redevelopment project is expected to generate WEIGHTED AVERAGE expenditures for the asset have been made and interest cost has been incurred. Activities necessary to •We recognized an asset management fee paid by our joint venture partner aggregating $7.0 million in connection with the disposition of 409 and 499 Illinois Street in 4Q25, which is development rights associated with existing operating campuses. of real estate primarily consisting of right-of-use assets and pre-acquisition costs related to projects that “guidance,” “goals,” “projects,” “estimates,” “anticipates,” “believes,” “expects,” “intends,” “may,” “plans,” “seeks,” “should,” “targets,” or “will,” or the negative of those words or similar words. These forward-looking contracted services, such as janitorial, engineering, and landscaping; property taxes and insurance; and noncontrolling interests, excludes liquidating distributions from asset sales, and excludes changes in (3)This loan is subject to a fixed SOFR floor of 0.75%. In order to calculate the Adjusted EBITDA margin, we divide Adjusted EBITDA by total represent our legal claim to each of our joint ventures’ assets, liabilities, or results of operations. In 20% capitalization for each month. The rate will vary each month due to changes in variable interest rates, reinvestment aggregating $2.36 billion for the years ended December 31, 2021 through 2025. Public/Private Mix (Cost)Tenant/Non-Tenant Mix (Cost) from this measure. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. of same properties. increases in rental income, net operating income, and cash flows. Our development and redevelopment Alexandria is known for our high-quality and diverse tenant base, with 53% of our develop, redevelop, or reposition a project include pre-construction activities such as entitlements, we decided to no longer pursue, gains or losses on early extinguishment of debt, changes in the included in other income. Other income in 4Q25 was $25.5 million, or 3.4% of total revenues, compared to an average of $19.5 million, or 2.5% of total revenues, for the preceding statements are based on our current expectations, beliefs, projections, future plans and strategies, anticipated events or trends, and similar expressions concerning matters that are not historical facts, as well as a property-level salaries. General and administrative expenses consist primarily of accounting and operating assets and liabilities as they represent timing differences. We are not able to forecast the net income of future periods without unreasonable effort and Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” and “Definitions and reconciliations” in the Supplemental Information for additional details. revenues as presented in our consolidated statements of operations. We believe that this supplemental addition, joint venture financial information may include financial information related to the outstanding debt balances, the proportion of variable-rate debt to fixed-rate debt, the amount and terms (1)Excludes our partner’s share of gain on sale of real estate aggregating $312.8 million at our consolidated real estate joint venture at 409 and 499 Illinois Street. •Dividend yield of 5.9% as of December 31, 2025 and dividend payout ratio of 33% for the projects are generally in locations that are highly desirable to high-quality entities, which we believe BiomedicalInstitutions(3) 4Q25 2025 Space Intentionally Blank annual rental revenue being generated from tenants that are investment-grade rated or permitting, design, site work, and other activities preceding commencement of construction of provision for expected credit losses on financial instruments, significant termination fees, acceleration of number of assumptions concerning future events. There can be no assurance that actual results will not be materially higher or lower than these expectations. These statements are subject to risks, uncertainties, corporate compensation, corporate insurance, professional fees, rent, and supplies that are incurred as five quarters. therefore do not provide a reconciliation for fixed-charge coverage ratio on a forward-looking basis. This 17% performance measure provides investors with additional useful information regarding the profitability of unconsolidated real estate joint ventures that we do not control. We believe that in order to facilitate for Space Intentionally Blank of interest rate hedge agreements, and the amount of loan fee and premium (discount) amortization. (2)During 4Q25, we finalized the Company’s 2025 capital plan and established an initial 2026 capital plan to fund 2026 construction primarily through the sale of land and non-core real estate assets. As a result, we recognized the following three months ended December 31, 2025. results in higher occupancy levels, longer lease terms, higher rental income, higher returns, and greater Under construction - 2027-2028 stabilization - $1.31 billion (51% leased/negotiating) Private Biotechnology Space Intentionally Blank Contractual lease expirations for properties classified as held for sale as of December 31, 2025 are excluded from the information on this page. aboveground building improvements. The advancement of pre-construction efforts is focused on publicly traded large cap companies. The quality, diversity, breadth, and depth of our stock compensation expense due to the resignations of executive officers, deal costs, the income tax assumptions, and other important factors that could cause actual results to differ materially from the results discussed in the forward-looking statements. Factors that might cause such a difference include, without part of corporate office management. We calculate operating margin as net operating income divided by Space Intentionally Blank is due to the inherent difficulty of forecasting the timing and/or amount of items that depend on market our operating activities. investors a clear understanding of our operating results and our total assets and liabilities, joint venture Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. impairment charges to reduce the carrying amounts of certain assets to their estimated fair values less cost to sell: Private Biotechnology 5.6x to 6.2x WEIGHTED AVERAGE Public Biotechnology Refer to “Definitions and reconciliations” in the Supplemental Information for additional details on key credit metrics. (1)Includes vacant square footage as of December 31, 2025. long-term asset value. reducing the time required to deliver projects to prospective tenants. These critical activities add (4) effect related to such items, and the amount of such items that is allocable to our unvested restricted significant relationships with our tenants provide Alexandria with high-quality and stable limitation, our failure to obtain capital (debt, construction financing, and/or equity) or refinance debt maturities, lower than expected yields, increased interest rates and operating costs, adverse economic or real total revenues. (1)Represents amounts in effect as of December 31, 2025. conditions outside of our control, including the timing of dispositions, capital events, and financing Potential tenant wind-downs Successful execution of Alexandria’s capital recycling strategy financial information should be examined in conjunction with our consolidated statements of operations PropertySubmarketImpairment (ARE Share)Asset TypeAssets designated as held for sale and sold in 4Q25:601, 611, 651, 681, 685, 701, and 751 Gateway Boulevard (50% and 51% consolidated JVs)South San Francisco$205,957Non-stabilized285, 299, 307, and 345 Dorchester Avenue (60% consolidated JV)Seaport Innovation District149,720Land3029 East Cornwallis RoadResearch Triangle82,540Land1290 and 1300 Rancho Conejo Boulevard and 2101 Corporate Center DriveNon-cluster68,566Non-stabilizedAssets designated as held for sale in 4Q25 and expected to be sold in 2026:88 Bluxome StreetSoMa333,446Land100 Edwin H. Land BoulevardCambridge156,370Land3825 and 3875 Fabian WayGreater Stanford144,682Stabilized/landMontrealCanada107,056Non-stabilizedOne Hampshire StreetCambridge105,694Non-stabilizedOther non-core assets designated as held for sale in 4Q2597,8911,451,922Noncontrolling interest’s share of impairment in real estate from consolidated real estate JVs265,266Consolidated impairment of real estate$1,717,188
| Space Intentionally Blank Total equity capitalization | 11% to 16% |
| (2)Excludes month-to-month leases aggregating 58,516 RSF as of December 31, 2025. significant value for future ground-up development and are required for the vertical construction of stock awards. We compute the amount that is allocable to our unvested restricted stock awards with (1)Includes smaller conversions to laboratory space through redevelopment. estate developments in our markets, our failure to successfully place into service and lease any properties undergoing development or redevelopment and our existing space held for future development or cash flows. Alexandria’s underwriting team and long-term industry relationships positively Incremental annual net operating income on development and redevelopment projects decisions, as well as quarterly components such as gain on sales of real estate, unrealized gains or (1)Refer to “Funds from operations and funds from operations, as adjusted, attributable to Alexandria’s common stockholders” under “Definitions and reconciliations” in the Supplemental Information for additional details. TOP 15% Other | |
| Space Intentionally Blank We are not able to forecast the net income of future periods without unreasonable effort and •Our 2026 guidance assumes reduction of rent in 2026 aggregating $20 - $25 million (or approximately $6 million per quarter at the midpoint of the range) related to potential tenant and balance sheets. Joint venture financial information should not be considered an alternative to our | |
| We exceeded the midpoint of our 2025 guidance for dispositions and sales of partial interests Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details. (3)Relates to a single-tenant, 100% pre-leased development project aggregating 466,598 RSF that expands the existing Campus Point by Alexandria Megacampus. At the beginning of 2026, the tenant will vacate 52,620 RSF from an Development projects generally consist of the ground-up development of generic and buildings. If we cease activities necessary to prepare a project for its intended use, interest costs related (2)Approximately 75% represents capitalized costs. nonforfeitable dividends using the two-class method. Under the two-class method, we allocate net 4%Public Steadily Improve Occupancyand Increase NOI, Focusing on Leasing to All Sectors of OurTenant Base, Including the Most Innovative Entities in a RapidlyChanging Environment BBB+Negative Baa1Negative 18%Tenant 3.6x to 4.1x | |
| (2)Our guidance for operating occupancy percentage in North America as of December 31, 2026 assumes an approximate 2% benefit related to a range of assets with vacancy that could potentially be sold during 2026 and/or qualify for redevelopment (including new properties acquired for that purpose), our failure to successfully operate or lease acquired properties, decreased rental rates, increased vacancy rates or failure to renew or replace We believe that in order to facilitate for investors a clear understanding of our operating (1)Initial occupancy dates are subject to leasing and/or market conditions. Stabilized occupancy may vary depending on single tenancy versus multi-tenancy. Multi-tenant projects may increase in occupancy over time. losses on non-real estate investments, impairments of real estate, impairments of non-real estate distinguish us from all other publicly traded REITs and real estate companies. Total equity capitalization is equal to the outstanding shares of common stock multiplied by the therefore do not provide a reconciliation for Adjusted EBITDA on a forward-looking basis. This is due to consolidated financial statements, which are presented and prepared in accordance with GAAP. wind-downs and downtime without immediate backfill. existing building, which generated annual rental revenue of $4.1 million as of 4Q25, to allow for the demolition and development of the new, build-to-suit life science building at this site. Refer to “New Class A/A+ development and by completing $1.81 billion of funding, primarily from sales of non-core assets and land, as well reusable laboratory facilities. Redevelopment projects consist of the permanent change in use of (3)Represents revenue- and non-revenue-enhancing capital expenditures before contributions from noncontrolling interests and tenant-funded and tenant-built landlord improvements. Incremental annual net operating income represents the amount of net operating income, on designation as held for sale by December 31, 2026 but that have not yet qualified for such designation as of December 31, 2025. to such project are expensed as incurred. (2)Represents a single-tenant project that expands the existing Campus Point by Alexandria Megacampus, where we currently have a 56.4% interest. The project is fully leased to a longtime multinational pharmaceutical tenant that currently income (after amounts attributable to noncontrolling interests) to common stockholders and to unvested expiring leases, defaults on or non-renewal of leases by tenants, adverse general and local economic conditions, an unfavorable capital market environment, decreased leasing activity or lease renewals, failure to results, net operating income should be examined in conjunction with net income or loss as presented in investments, and changes in provision for expected credit losses on financial instruments. Our attempt Refer to “Initial stabilized yield (unlevered)” under “Definitions and reconciliations” in the Supplemental Information for additional details. We are not able to forecast the net income of future periods without unreasonable effort and closing price on the last trading day at the end of each period presented. the inherent difficulty of forecasting the timing and/or amount of items that depend on market conditions (1)Quarter annualized. redevelopment properties: current projects” in the Supplemental Information for additional details. | |
| Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details on the square footage in service and under construction, if applicable. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (4)The top two revenue- and non-revenue-enhancing capital expenditure projects in 2026 represent approximately 55% of the total spending within this category. The first project relates to a property located at the Alexandria Center® for acquired office, warehouse, or shell space into laboratory space. We generally will not commence new as sales to owner/users. During 4Q25, we completed $1.47 billion of dispositions. (3)Refer to “Capitalization of interest” in the Supplemental Information for additional details. (1)In addition to the real estate joint ventures listed, we have one consolidated real estate joint venture in the Greater Boston market in which a partner holds a $49.6 million redeemable noncontrolling interest earning a fixed return as an annual basis, expected to be realized upon a project being placed into service and achieving full occupies two buildings within the Megacampus: one building aggregating 52,620 RSF and another building aggregating 52,853 RSF. These buildings generated annual rental revenue of $7.5 million as of 4Q25. At the beginning of 2026, the TOP 15% GENERAL AND ADMINISTRATIVE EXPENSES AS A PERCENTAGE OF NET OPERATING INCOME(4) (5) restricted stock awards with nonforfeitable dividends by applying the respective weighted-average obtain LEED and other healthy building certifications and efficiencies, and other risks and uncertainties detailed in our filings with the Securities and Exchange Commission (“SEC”). Accordingly, you are cautioned our consolidated statements of operations. Net operating income should not be considered as an We use Adjusted EBITDA as a supplemental performance measure of our operations, for (4)Key lease expirations with expected downtime represent space expected to become vacant at lease expiration and re-leased to new tenants. We have identified prospects or have early discussions with prospective tenants for 468,470 (2)Change in net operating income (cash basis) includes the impact of operating properties disposed of after to predict these amounts may produce significant but inaccurate estimates, which would potentially be therefore do not provide a reconciliation for net debt and preferred stock to Adjusted EBITDA on a outside of our control, including the timing of dispositions, capital events, and financing decisions, as Executive and senior management team Space Intentionally Blank CREDIT RATING RANKING AMONG ALL PUBLICLY TRADED U.S. REITS(4) | |
| (1)An observable price is a price observed in an orderly transaction for an identical or similar investment of the same General and administrative expenses Advanced Technologies - South San Francisco Megacampus in our South San Francisco submarket, which is leased to a new tenant and is undergoing its first major renovation in 12 years. The second project relates to a property at the Strong and flexible balance sheet with significant liquidity; top 15% credit rating ranking among all (1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 20,444 RSF that were vacant and/or unleased at delivery. (4)Represents realized gains and losses included in funds from operations per share - diluted, as adjusted. Excludes unrealized gains and losses and significant impairments realized on non-real estate investments, if any. Refer to of December 31, 2025. tenant will vacate the 52,620 RSF building, and during 2028, the tenant will vacate the 52,853 RSF building. We expect to fund the majority of future construction costs at the Megacampus until our ownership interest increases to 75%, after development projects for aboveground construction of new Class A/A+ laboratory space without first Other Advanced Technology (2) | |
| (dollars in millions)Sales PriceYTD 3Q25$3414Q251,471Total 2025 dispositions and sales of partial interests(1)$1,812 occupancy. Incremental annual net operating income is calculated as the initial stabilized yield multiplied (1)We expect to provide total estimated costs and related yields for each project over the next several quarters. Cash interest RSF of the 1.0 million RSF listed under remaining expiring leases. We continue to evaluate business plans and re-leasing strategies for these projects to maximize occupancy and rental revenue. We expect downtime for 2026 key lease shares outstanding during each quarter-to-date and year-to-date period. This may result in a difference January 1, 2024. Excluding these dispositions, net operating income (cash basis) annualized for the three not to place undue reliance on such forward-looking statements. All forward-looking statements are made as of the date of this Earnings Press Release and Supplemental Information, and unless otherwise stated, alternative to net income or loss as an indication of our performance, nor as an alternative to cash flows financial and operational decision-making, and as a supplemental means of evaluating period-to-period misleading for our investors. forward-looking basis. This is due to the inherent difficulty of forecasting the timing and/or amount of Percentage of ARE’s Annual Rental Revenue BBB+Negative Baa1Negative | |
| Total market capitalization issuer. Observable price changes result from, among other things, equity transactions for the same issuer with well as quarterly components such as gain on sales of real estate, unrealized gains or losses on non- Net operating income is a non-GAAP financial measure calculated as net income (loss), the Alexandria Technology Square® Megacampus in our Cambridge submarket, which is undergoing its first major renovation in 16 years. (2)Represents the average delivery date for deliveries that occurred during the current quarter, weighted by annual rental revenue. “Investments” in the Supplemental Information for additional details. •General and administrative expenses for the year ended December 31, 2025 was $117.0 million and $28.0 million for the fourth quarter of 2025. Our guidance range for 2026 general (2)Represents a property currently under construction or in our future development and redevelopment pipeline. Refer to the sections under “New Class A/A+ development and redevelopment properties” in the Supplemental which future capital would be contributed pro rata with our joint venture partner. Future projects with critical milestones in 2026 - Non-Megacampus projects - $987.5 million 82%Non-Tenant publicly traded U.S. REITs expirations to be approximately 6 to 24 months on a weighted-average basis, and we expect these properties to remain operating properties. securing significant pre-leasing for such space, except when there is solid market demand for high- (2)Refer to footnote 2 on the prior page for additional details. Alexandria’s executive and senior management team has unique experience and by the project’s total cost at completion. months ended December 31, 2025 and for the year ended December 31, 2025 would have increased by 1.4% of the summation of the quarter-to-date and year-to-date amounts. Neither funds from operations nor Assets sold in 2025 or designated as held for sale as of 4Q25 - $1.12 billion 96%Private Biomedical Institutions we assume no obligation to update this information and expressly disclaim any obligation to update or revise any forward-looking statements, whether as a result of new information, future events, or otherwise. For as a measure of our liquidity or our ability to make distributions. comparisons on a consistent basis. Adjusted EBITDA is calculated as earnings before interest, taxes, similar rights and obligations executed during the reporting period, including subsequent equity offerings or other items that depend on market conditions outside of our control, including the timing of dispositions, real estate investments, impairments of real estate, impairments of non-real estate investments, and (5)Represents contractual capital commitments from existing real estate joint venture partners to fund construction. (1)Includes expected partial deliveries through 2026 from projects expected to stabilize in 2027-2028, including (3)Occupancy reflects total operating RSF placed in service as of each respective delivery date when the space was placed into service. Subsequent occupancy changes are not reflected. most directly comparable financial measure calculated and presented in accordance with GAAP, (5)Our debt repayment goals include repaying existing short-term borrowings, including amounts outstanding on our commercial paper program, repaying our 2026 unsecured senior note payable maturities aggregating $650 million, and Information for additional details. Non-Stabilized Properties and administrative expenses is $134 million to $154 million, with a midpoint of $144 million, or a quarterly average of approximately $36 million. Despite the anticipated increase in (1)Excludes a gain on sale of interest related to an unconsolidated real estate joint venture of $458 thousand, which is classified as equity in earnings of unconsolidated real estate joint ventures in our consolidated statement of operations. (3)Represents dollar amount rounded to the nearest $10 million and includes preliminary estimated amounts for projects listed as TBD. Cash interest is equal to interest expense calculated in accordance with GAAP plus and 6.2%, respectively, compared to the corresponding periods in 2024. quality Class A/A+ properties. Property or CampusSubmarketRSF% of Leased/NegotiatingWeighted Average Expiration DateLocated on MegacampusAnnual Rental Revenue From Lease Expirations/Known Vacancies Alexandria Stanford Life Science DistrictGreater Stanford137,970 - %June 2026$12,899One Alexandria SquareTorrey Pines118,22538January 2026X10,064Alexandria Center® at One Kendall SquareCambridge92,775 - May 2026X7,7839625 Towne Centre DriveUniversity Town Center163,648 - January 20266,5205810/5820 Nancy Ridge DriveSorrento Mesa83,354100January 20263,389Alexandria Center® at Kendall SquareCambridge45,636 - January 2026X4,564RemainingVarious519,8514May 2026(6)25,7921,161,45913%April 2026$71,011 Annual rental revenue and RSF include 100% of each property managed by us in North America. Refer to “Annual rental revenue” and “Investment-grade or publicly traded large cap tenants” under “Definitions and reconciliations” in the Total market capitalization is equal to the sum of total equity capitalization and total debt. expertise in creating, owning, and operating highly dynamic and collaborative CREDIT RATING RANKING AMONG ALL PUBLICLY TRADED U.S. REITS(4) Private Biotechnology reported equity transactions related to the same issuer. funds from operations, as adjusted, should be considered as alternatives to net income (determined in •$20.75 billion in total market capitalization. more discussion relating to risks and uncertainties that could cause actual results to differ materially from those anticipated in our forward-looking statements, and risks to our business in general, please refer to our depreciation, and amortization (“EBITDA”), excluding stock compensation expense, gains or losses on capital events, and financing decisions, as well as quarterly components such as gain on sales of real changes in provision for expected credit losses on financial instruments. Our attempt to predict these speculative future leasing that is not yet fully committed. Refer to the initial and stabilized occupancy years (4)During December 2025, we sold our 50% controlling interest in a consolidated real estate joint venture at 651 Gateway Boulevard. Refer to “2025 Dispositions and sales of partial interests” in the Earnings Press Release for additional potentially repaying other unsecured senior notes payable, including our 2027 maturity. (3)Includes 1450, 1500, and 1700 Owens Street and 455 Mission Bay Boulevard South. excluding equity in the earnings of our unconsolidated real estate joint ventures, general and Advanced Technology Biomedical Institutions | |
| (2)Represents a retail shopping center with future development opportunity. We originally acquired the property in 2021 with the intent to demolish the retail center and develop it into laboratory space. However, due to the project’s financial (4)Represents our share of investment based on our current ownership percentage upon completion of development or redevelopment projects. Our share of investment will be adjusted as our ownership percentage increases at the Campus general and administrative expenses in 2026 compared to 2025, the midpoint of our guidance range for 2026 of $144 million, represents a 14% reduction compared to 2024, and capitalized interest, less amortization of loan fees and debt premiums (discounts). Refer to the definition (1)Includes one property aggregating 247,743 RSF previously included in our Canada market. Supplemental Information for additional details, including our methodology of calculating annual rental revenue from unconsolidated real estate joint ventures and average market capitalization, respectively. | |
| Megacampus real estate in key life science cluster locations to catalyze innovation. From accordance with GAAP) as indications of financial performance, or to cash flows from operating SEC filings, including our most recent annual report on Form 10-K and any subsequent quarterly reports on Form 10-Q. We are not able to forecast the net income of future periods without unreasonable effort and early extinguishment of debt, gains or losses on sales of real estate, impairments of real estate, changes •$8.35 billion in total equity capitalization. under “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Continued successful management and reduction of general and administrative expenses details. (6)We expect to achieve a weighted-average capitalization rate on our projected 2026 non-core operating dispositions (includes stabilized and non-stabilized properties and excludes land) in the 8.5% - 9.5% range. We expect dispositions of estate, unrealized gains or losses on non-real estate investments, impairments of real estate, (4)Includes 10210, 10260, 10290, and 10300 Campus Point Drive and 4110, 4135, 4155, 4161, 4165, 4224, and 4242 Campus Point Court. amounts may produce significant but inaccurate estimates, which would potentially be misleading for our outlook and the substantial capital that development would have required, we decided to recycle the capital generated by the disposition into our development and redevelopment pipeline. administrative expenses, interest expense, depreciation and amortization, impairments of real estate, Point project. (2)Decline in occupancy primarily related to temporary vacancy from one lease expiration aggregating 50,552 RSF in our Bothell submarket. This space is already re-leased, with occupancy expected to commence in 1Q26. of fixed-charge coverage ratio for a reconciliation of interest expense, the most directly comparable cumulative anticipated savings aggregating $76 million for 2025 and 2026. Pre-construction activities include entitlements, permitting, design, site work, and other activities (determined in accordance with GAAP) as measures of liquidity, nor are they indicative of the Information for additional details. design to development to the management of our high-quality, sustainable real estate, as (5)As of December 31, 2025, our Canada project was designated as held for sale. land to represent 25% - 35% of our total dispositions and sales of partial interests for the year ending December 31, 2026. We expect the remaining balance to include approximately 25% - 35% core assets and 35% - 45% non-core assets. (5)The noncontrolling interest share of our real estate joint venture partner is anticipated to decrease to 25%, as we expect to fund the majority of future construction costs at the campus until our ownership interest increases to 75%, therefore do not provide a reconciliation for net operating income on a forward-looking basis. This is due in provision for expected credit losses on financial instruments, and significant termination fees. Adjusted •Net debt and preferred stock to Adjusted EBITDA of 5.7x and fixed-charge coverage ratio of impairments of non-real estate investments, and changes in provision for expected credit losses on investors. (3)We held a 50% ownership interest at 601, 611, 651, 681, 685, and 701 Gateway Boulevard and a 51% interest at 751 Gateway Boulevard. At the time of sale, these properties had operating and redevelopment properties occupancy of gains or losses on early extinguishment of debt, gains or losses on sales of real estate, and investment Percentage of Total Average Real Estate Basis Capitalized During 2025 | |
| Types of dispositions in 2025(1)% of Sales PriceLand21%Non-stabilized properties59Stabilized properties 20Total 2025 dispositions100% (3)10 properties in Canada were designated as held for sale in 4Q25 and the remaining one property was reclassified into our non-cluster market. (1)Based on annual rental revenue in effect as of December 31, 2025. •General and administrative expenses as a percentage of net operating income for the year financial measure calculated and presented in accordance with GAAP, to cash interest. activities preceding commencement of construction of aboveground building improvements. The 2019 - 2025 DISPOSITIONS AND PARTIAL INTEREST SALES | |
| (2)Represents the RSF of projects expected to stabilize in 2026. Does not include RSF for partial deliveries As of January 26, 2026, our share of pending transactions subject to non-refundable deposits, signed letters of intent, or purchase and sale agreement negotiations aggregated $180.7 million. Leasing activity includes 100% of results for properties in North America in which we have an investment. after which future capital would be contributed pro rata with our partner. Refer to “New Class A/A+ development and redevelopment properties: current projects” in the Supplemental Information for additional details. availability of funds for our cash needs, including our ability to make distributions. This document is not an offer to sell or a solicitation to buy securities of Alexandria Real Estate Equities, Inc. Any offers to sell or solicitations to buy our securities shall be made only by means of a to the inherent difficulty of forecasting the timing and/or amount of items that depend on market well as our ongoing cultivation of collaborative environments with unique amenities and EBITDA also excludes unrealized gains or losses and significant realized gains or losses and 62%, with a weighted-average lease term of 5.1 years. Due to macroeconomic conditions in South San Francisco, including significant new supply, lower life science tenant demand, and ongoing challenges leasing both laboratory and financial instruments. Our attempt to predict these amounts may produce significant but inaccurate As of December 31, 2025. Annual rental revenue represents amounts in effect as of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details, including our methodology of calculating 3.7x for 4Q25 annualized. 2025 DISPOSITIONS AND SALES OF PARTIAL INTERESTS BY REAL ESTATE CLASSIFICATION | |
| (4)Includes temporary vacancies as of December 31, 2025 aggregating 899,259 RSF, or 2.5% of total operating RSF, primarily in the Greater Boston, San Francisco Bay Area, and Seattle markets, which are leased and expected (2)Eikon Therapeutics, Inc. is a private biotechnology company led by renowned biopharmaceutical executive Roger Perlmutter, formerly an executive vice president at Merck & Co., Inc. As of February 25, 2025, the company has raised over income or loss. We believe net operating income provides useful information to investors regarding our ended December 31, 2025 were 5.6% - the lowest level in the past ten years for the (1)In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon maturity. No gain or loss was incurred in connection with this repayment. through 2026 from projects expected to stabilize in 2027-2028. advancement of pre-construction efforts is focused on reducing the time required to deliver projects to (7)In January 2026, we repaid $300.0 million of 4.30% unsecured senior notes payable upon maturity, funded temporarily with borrowings under our commercial paper program. We expect to repay these temporary borrowings with proceeds (6)Includes 9605, 9645, 9675, 9725, 9735, 9805, 9808, 9855, and 9868 Scranton Road and 10055, 10065, and 10075 Barnes Canyon Road. Realized gains on non-real estate investments office space, we reassessed the project’s financial outlook and the substantial capital required to lease vacant space and to complete the redevelopment of 651 Gateway Boulevard and future development opportunities. As a result, we sold prospectus approved for that purpose. Unless otherwise indicated, the “Company,” “Alexandria,” “ARE,” “we,” “us,” and “our” refer to Alexandria Real Estate Equities, Inc. and our consolidated subsidiaries. annual rental revenue from unconsolidated real estate joint ventures. conditions outside of our control, including the timing of dispositions, capital events, and financing impairments that result from our non-real estate investments. These non-real estate investment amounts Non-Income-Producing Assets(4) as a Percentage of Gross Assets events, the Alexandria team has a best-in-class reputation of excellence in life science real estimates, which would potentially be misleading for our investors. to be occupied upon completion of building and/or tenant improvements. The weighted-average expected delivery date is approximately August 2026 and the expected annual rental revenue is approximately $52 million. $1.16 billion in private venture capital funding. •As of December 31, 2025 financial condition and results of operations because it primarily reflects those income and expense (1)Excludes month-to-month leases aggregating 58,516 RSF and 136,131 RSF as of December 31, 2025 and 2024, respectively. During the year ended December 31, 2025, we granted free rent concessions averaging 1.5 (2)Refer to footnotes 2 through 4 on page 52 under “Fixed-rate and variable-rate debt” for additional details. | |
| Refer to “Joint venture financial information” under “Definitions and reconciliations” in the Supplemental Information for additional details. (3)Represents the current leased/negotiating percentage of development and redevelopment projects that are Company and approximately half the average of other S&P 500 REITs. In 2025, we realized from future dispositions and sales of partial interests. No gain or loss was incurred in connection with this repayment. (7)Includes 9965, 9975, 9985, and 9995 Summers Ridge Road. prospective tenants. These critical activities add significant value for future ground-up development and the consolidated joint ventures for a gross price of $600.0 million ($560.4 million net of seller credits and sales costs), of which our share of the price (after seller credits) was $283.2 million. •Realized gains included in funds from operations per share - diluted, as adjusted, for the year ended December 31, 2025 were $115.7 million and $21.1 million for the fourth quarter We are not able to forecast the net income of future periods without unreasonable effort and | |
| Alexandria®, Lighthouse Design® logo, Building the Future of Life-Changing Innovation®, That’s What’s in Our DNA®, Megacampus™, At the Vanguard and Heart of the Life Science Ecosystem™, Alexandria decisions, as well as components such as gain on sales of real estate, unrealized gains or losses on (3)Includes leases, which are not subject to annual appropriations, with governmental entities such as the NIH and the General Services Administration. Approximately 2% of the annual rental revenue derived from our leases with the United are classified in our consolidated statements of operations outside of total revenues. estate. Alexandria’s highly experienced management team includes regional market Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details, including its reconciliation from the most directly comparable financial measure presented in accordance with GAAP. months per annum. •Significant liquidity of $5.30 billion, or 3.7x of our debt maturities through 2028. items that are incurred at the property level. Therefore, we believe net operating income is a useful expected to stabilize through 2026. (1) (2) (2) | |
| (8)In addition to the real estate joint ventures listed, we hold an interest in two insignificant unconsolidated real estate joint ventures. (1)Relates to our partners’ share of impairment charges recognized in connection with real estate properties held by consolidated joint ventures at 601, 611, 651, 681, 685, 701, and 751 Gateway Boulevard and 285, 299, 307, and cost reductions of $51.3 million, or 30%, compared to 2024, primarily from cost-control and are required for the vertical construction of buildings. Ultimately, these projects will provide high-quality (4)Represents the sale of a non-stabilized campus located outside of a Megacampus ecosystem. At the time of sale, the campus was 76% occupied, with a weighted-average remaining lease term of less than four years. Given our strategy to (1)Represents the percentage of our annual rental revenue generated by professional services, finance, construction/real estate companies, and retail-related tenants. States Government is cancellable prior to the lease expiration date. of 2025. Our guidance range for 2026 realized gains on non-real estate investments is $60 million to $90 million, with a midpoint of $75 million (or a quarterly average of therefore do not provide a reconciliation for funds from operations on a forward-looking basis. This is | |
| Center®, Alexandria Technology Square®, Alexandria Technology Center®, and Alexandria Innovation Center® are copyrights and trademarks of Alexandria Real Estate Equities, Inc. All other company names, non-real estate investments, impairments of real estate, impairments of non-real estate investments, (2)Includes (i) a one-year lease extension aggregating 247,743 RSF with an investment-grade-rated government institution tenant at an office property in Canada and (ii) a 7.4-year lease aggregating 83,354 RSF with an directors with leading reputations and long-standing relationships within the life science measure for investors to evaluate the operating performance of our consolidated real estate assets. Net •Only 11% of our total debt matures through 2028. (1)Includes the real estate basis related to the 899,259 RSF of vacant space as of December 31, 2025 that is leased with future delivery. The weighted-average expected delivery date is approximately August 2026. (9)Represents a joint venture with a local real estate operator in which our joint venture partner manages the day-to-day activities that significantly affect the economic performance of the joint venture. | |
| 345 Dorchester Avenue. Refer to “2025 dispositions and sales of partial interests” in the Earnings Press Release for additional details. (2)71% of our annual rental revenue from advanced technologies tenants is from investment-grade or publicly traded large cap tenants. invest into our Megacampus and the significant near‑term capital required to re‑stabilize the asset, we decided to reinvest the disposition proceeds into other projects with greater value-creation opportunities. (1)Primarily related to two non-real estate investments in privately held entities that do not report NAV. facilities and are expected to generate significant revenue and cash flows. efficiency initiatives. Some of these cost savings are temporary in nature, and we anticipate (4)Includes (i) ground leases for land at 1455 and 1515 Third Street (two buildings aggregating 422,980 RSF) and (ii) leases at 1655 and 1725 Third Street (two buildings aggregating 586,208 RSF) in our Mission Bay submarket owned by | |
| (1)Excludes future incremental annual net operating income from recently delivered spaces aggregating 20,444 RSF that were vacant and/or unleased at delivery. due to the inherent difficulty of forecasting the timing and/or amount of items that depend on market approximately $18.8 million). Refer to “Investments” in the Supplemental Information for additional details. trademarks, and logos referenced herein are the property of their respective owners. and changes in provision for expected credit losses on financial instruments. Our attempt to predict anchor tenant at one property in our Sorrento Mesa submarket. At acquisition, the office property in Canada was originally targeted for a future change in use, but we instead renewed the existing tenant through the (1)Represents the weighted-average interest rate as of the end of the applicable period, including amortization of loan fees, amortization of debt premiums (discounts), and other bank fees. (2)Approximately 74% of future pipeline projects are expected to reach anticipated pre-construction milestones, including various phases of entitlement, design, site work, and other activities necessary to begin aboveground communities in their respective innovation clusters. We believe that our experience, (2)Relates to our partner’s share of the gain on sale of real estate recognized upon the disposition of the properties at 409 and 499 Illinois Street. operating income on a cash basis is net operating income adjusted to exclude the effect of straight-line (1)Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details, including future development and redevelopment square feet currently included in rental properties. (3)82% of our annual rental revenue from biomedical institutions is from investment-grade or publicly traded large cap tenants. •12.1 years weighted-average remaining term of debt, longest among S&P 500 REITs. (5)Represents two life science buildings in which we held a 25% ownership interest. At the time of sale, the properties were 40% occupied, with a weighted-average remaining lease term of 8.3 years. These properties were sold by the joint (2)In November 2025, we contributed certain publicly traded securities to an unconsolidated joint venture, which resulted in a realized loss of $103.3 million on one transaction that was previously reflected as unrealized losses within our unconsolidated real estate joint venture in which we have an ownership interest of 10%. Annual rental revenue is presented using 100% of the annual rental revenue from our consolidated properties and our share of annual rental that approximately half of the cost reduction achieved in 2025 will continue in 2026. (2)Includes expected partial deliveries through 2026 from projects expected to stabilize in 2027-2028, including speculative future leasing that is not yet fully committed. Our share of incremental annual net operating income from projects beginning of 2027, with no incremental capital investment. We continue to evaluate business strategy for this property, including the potential sale of the asset, subject to market conditions. Excluding these leases, rental Refer to “Same property comparisons” under “Definitions and reconciliations” in the Supplemental Information for additional details, including a reconciliation of same properties to total properties. “Definitions and reconciliations” also conditions outside of our control, including the timing of dispositions, capital events, and financing (1)Excludes the exchange of partial interests in two consolidated real estate joint ventures, Pacific Technology (1)Image represents 60 Sylvan Road on the Alexandria Center® for Life Science - Waltham Megacampus. The project is expected to capture demand in our Route 128 submarket. these amounts may produce significant but inaccurate estimates, which would potentially be misleading (2)Reflects any extension options that we control. vertical construction, on a weighted-average real estate investment basis by May 2026. At each milestone date, we will evaluate whether to proceed with additional pre-construction and/or construction activities based on leasing Refer to “Same property performance” and “Definitions and reconciliations” in the Supplemental Information for additional details. “Definitions and reconciliations” contains the definition of “Net operating income” and its reconciliation (3)Represents an allocation of joint venture earnings to redeemable noncontrolling interests for properties in the Greater Boston and San Francisco Bay Area markets. These redeemable noncontrolling interests earn a fixed return on WEIGHTED-AVERAGE REMAINING DEBT TERM (IN YEARS) | |
| (2)Balances exclude accumulated depreciation and our share of the cost basis associated with our properties held by our unconsolidated real estate joint ventures, which is classified as investments in unconsolidated real estate joint expertise, reputation, and key relationships in the real estate and life science industries venture to an existing tenant following its exercise of a purchase right included in its lease agreement. The gross sales price was $767.1 million ($721.1 million net of seller credits and sales costs), of which our share of the price (after seller rent, amortization of acquired above- and below-market lease revenue, amortization of deferred revenue investment income in our consolidated statement of operations. The unconsolidated joint venture sold these securities and distributed $39.9 million to us in December 2025. •Our fixed-rate debt represents 97.2% of our total debt, which provides predictability in debt revenue from our unconsolidated real estate joint ventures. Excluding these ground leases, the weighted-average remaining lease term for our top 20 tenants was 7.9 years as of December 31, 2025. contains definitions of “Tenant recoveries” and “Net operating income” and their respective reconciliations from the most directly comparable financial measures presented in accordance with GAAP. expected to be placed into service primarily commencing through 2026 is projected to be $74 million. Refer to the initial and stabilized occupancy years under “New Class A/A+ development and redevelopment properties: current | |
| Development, redevelopment, and pre-construction spending also includes the following rates for renewed and re-leased space for the three months ended December 31, 2025 increased by 4.6% and decreased by 5.0% (cash basis). Park and 199 East Blaine Street, during the three months ended September 30, 2025. Refer to ”2025 As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. •Compared to the general and administrative expenses for the year ended December 31, demand and/or market conditions, pause future investments, or consider the potential dispositions of real estate assets. decisions, as well as components such as gain on sales of real estate, unrealized gains or losses on (3)Refer to footnotes 2 through 4 under “Fixed-rate and variable-rate debt” in “Summary of debt” for additional details. from the most directly comparable financial measure presented in accordance with GAAP. for our investors. their investment rather than participate in the operating results of the properties. (1)Based on the midpoint of our guidance range for 2026 general and administrative expenses disclosed on January 26, 2026. ventures in our consolidated balance sheet. Refer to “Investments in real estate” under “Definitions and reconciliations” in the Supplemental Information for additional details. credits) was $180.3 million. Our share of gain on sales of real estate was $103.9 million. (1)Source: U.S. House Committee on Energy and Commerce, “The 21st Century Cures Discussion Document White Paper,” January 27, 2015. (3)Consists of unrealized gains of $24.2 million primarily resulting from the increase in fair values of our investments in privately held entities that report NAV and $74.3 million resulting from accounting reclassifications of unrealized losses related to tenant-funded and tenant-built landlord improvements, and changes in the provision for provide Alexandria significant competitive advantages in attracting new business (5)Represents one lease encompassing three properties located on the Alexandria Stanford Life Science District campus, which we acquired in 2022 and for which we are evaluating business strategy based on market conditions. This lease (1)Image represents 500 North Beacon Street on The Arsenal on the Charles Megacampus. projects” in the Supplemental Information for additional details. servicing costs. Since 2021, our quarter-end fixed-rate debt has averaged 96.7%. (3)Calculated in accordance with standards established by the Nareit Board of Governors. (3)Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in the Supplemental Information for additional details, including total project costs. (1)Includes the impact of initial free rent concessions that burned off after January 1, 2024 for development and redevelopment projects that were placed into service in 2023, and accordingly are part of our same property pool for the costs: (i) amounts to bring certain acquired properties up to market standard and/or other costs identified dispositions and sales of partial interests” in this Earnings Press Release for additional details. (1)Represents the average quarterly percentage fixed-rate debt as of each quarter-end from January 1, 2021 through December 31, 2025. (3)The weighted-average date as of which capitalization of interest ceased was in early December 2025. (4)In January 2026, we repaid our 4.30% unsecured senior notes payable upon maturity. No gain or loss was incurred in connection with this repayment. 2024, we expect to achieve a savings of $76 million of cumulative general and non-real estate investments, impairments of real estate, impairments of non-real estate investments, | |
| (4)Refer to “Funds from operations and funds from operations per share” in the Earnings Press Release and “Definitions and reconciliations” in the Supplemental Information for additional details. (2)Trailing twelve months ended December 31, 2025. (3)Our share of investment in our development and redevelopment pipeline is $6.35 billion. (6)Represents a non-stabilized property that was sold to a user. (1)We plan to lease this property as office which will require less incremental capital. As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (2)Source: PhRMA, “Medicines in Development for Chronic Diseases: 2024 Report.” recognized in prior periods into realized losses upon our realization of investments during the three months ended December 31, 2025. (5)Represents key 2027 lease expirations with expected downtime primarily in our Greater Boston, San Francisco Bay Area, and San Diego markets aggregating 1.2 million RSF with a weighted-average expiration date in March 2027 and with Cloud Software Group, Inc. (formerly known as TIBCO Software, Inc.) was in place when we acquired the properties, of which 137,970 RSF has lease expirations through 2026. Refer to “Contractual lease expirations” in the (1)Includes an asset management fee paid by our joint venture partner of $7.0 million, which was recognized in connection with the disposition of 409 and 499 Illinois Street. Refer to “2025 dispositions and sales of partial interests” in the (2)Image represents 10955 Alexandria Way on the One Alexandria Square Megacampus. expected credit losses on financial instruments required by GAAP. We believe that net operating income | |
| (3)Our share of incremental annual net operating income from projects expected to stabilize in 2027-2028 is projected to be $92 million. opportunities. (4)In November 2025, we contributed certain publicly traded securities to an unconsolidated joint venture, which resulted in a realized loss of $103.3 million on one transaction that was previously reflected as unrealized losses within year ended December 31, 2025, including at 325 Binney Street in our Cambridge submarket and 15 Necco Street in our Seaport Innovation District submarket. Excluding the impact of these initial free rent concessions, same property (4)In addition to capitalized interest, we incur additional capitalized project costs, including property taxes, insurance, payroll, and other costs directly related and essential to the construction of Class A/A+ properties. If we cease (2)Represents net debt and preferred stock to Adjusted EBITDA for the fourth quarter annualized. •Total debt and preferred stock to gross assets of 31%. during the acquisition process (generally within two years of acquisition) and (ii) permanent conversion Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (1)For the three months ended December 31, 2025. | |
| (3)Source for S&P 500 REIT data: S&P Global Market Intelligence. Represents the annual average of the years ended December 31, 2024 and 2023 and the trailing twelve months ended September 30, 2025. (4)Excludes properties classified as held for sale, of which land parcels represent approximately 1% of total non-income producing assets. and changes in provision for expected credit losses on financial instruments. Our attempt to predict As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (1)Represents aggregate sales from outright sales and sales of partial interests. administrative expense in 2025 and 2026 based upon the midpoint of our guidance range (7)We provided seller financing of $33.0 million. (1)Represents the average quarterly percentage fixed-rate debt as of each quarter-end from January 1, 2021 through December 31, 2025. annual rental revenue aggregating $72 million. Included in these expirations are seven leases aggregating 531,984 RSF and $42.3 million in annual rental revenue with four separate tenants that will relocate to our current active (3)Source: Centers for Disease Control and Prevention, “Heart Disease Facts,” October 24, 2024. Represents the latest published data, which reflects the U.S. estimate for 2022. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. (4)Primarily relates to the increase in fair values of our investments in publicly traded entities during the year ended December 31, 2025. Supplemental Information for additional details. Earnings Press Release for additional details. •As of December 31, 2025, the book value of our real estate assets designated as held for | |
| (4)Represents the current leased/negotiating percentage of development and redevelopment projects that are expected to stabilize through 2026. on a cash basis is helpful to investors as an additional measure of operating performance because it investment income in our consolidated statement of operations. The unconsolidated joint venture sold these securities and distributed $39.9 million to us in December 2025. (1)Refer to “2025 dispositions and sales of partial interests” in the Earnings Press Release for additional details. activities necessary to prepare a project for its intended use, costs related to such project are expensed as incurred. Annualized capitalized operating expenses and payroll represent approximately 2% and 1%, respectively, of net operating income (cash basis) for the year ended December 31, 2025 would have decreased by 1.4%. (3)Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025. (2)Percentages calculated based on our annual rental revenue in effect as of December 31, 2025. of space for highly flexible, move-in-ready laboratory space to foster the growth of promising early- and | |
| (4)Refer to “Net operating income” under “Definitions and reconciliations” in the Supplemental Information for additional details. development and redevelopment projects upon completion of their tenant improvements. On a combined basis, these tenants will expand their footprint within our portfolio by over 41%. Additionally, we have identified prospects or have (1)Represents non-core assets outside our Megacampus ecosystems. (2)Total gains and impairments represent our share and include any amounts related to sales of partial interests recognized in additional paid-in capital. (8)Our share of dispositions completed during the three months ended December 31, 2025 had annual net operating income of $93 million (based on 3Q25 annualized results) with a weighted-average disposition date of December 9, 2025. (2)Represents net debt and preferred stock to Adjusted EBITDA for the fourth quarter annualized. (4)Source: National Cancer Institute, “Cancer Statistics,” updated May 7, 2025. Represents the latest published data, which reflects 2018 - 2021 data, not including 2020 due to lack of collection during COVID-19 pandemic. (1)Source: AstraZeneca, “ AstraZeneca plans $2 billion manufacturing investment in Maryland, supporting 2,600 jobs and catalyzing economic growth,” November 21, 2025. (1)Quarter annualized. these amounts may produce significant but inaccurate estimates, which would potentially be misleading (5)Primarily relates to the accounting reclassifications of unrealized gains recognized in prior periods into realized gains upon our realization of investments during the year ended December 31, 2024. for 2026 general and administrative expenses. (6)Altos Labs, Inc. is a private biotechnology company led by Hal Barron, M.D., former Chief Scientific Officer of GlaxoSmithKline. Altos Labs is backed by a group of prominent long-term investors and has raised $3.0 billion in private (2)Refer to footnote 1 and 2 in “Funds from operations and funds from operations per share” in the Earnings Press Release for additional details. (1)Refer to page 2 in the Earnings Press Release and “Summary of properties and occupancy” in the Supplemental Information for additional details. | |
| (5)Represents the RSF related to projects expected to stabilize in 2026. Does not include RSF for partial deliveries through 2026 from projects expected to stabilize in 2027-2028. the total average real estate basis subject to capitalization for 2025. sale aggregated $581.7 million. We expect to sell these assets in 2026. (5)Primarily related to two non-real estate investments in privately held entities that do not report NAV. (2)Decrease in net operating income includes the impact of operating properties disposed of after January 1, 2024. Excluding these dispositions, net operating income for the three months ended December 31, 2025 and the year ended (4)Top 15% ranking represents credit rating levels from S&P Global Ratings and Moody’s Ratings for publicly traded U.S. REITs, from Bloomberg Professional Services and Nareit, as of December 31, 2025. eliminates straight-line rent revenue and the amortization of acquired above- and below-market leases (3)Represents the weighted-average remaining term based on annual rental revenue in effect as of December 31, 2025. early discussions with prospective tenants for 302,028 RSF of the total 1.2 million RSF. We expect downtime to be approximately 9 to 24 months on a weighted-average basis, and we expect these properties to remain operating properties. growth-stage life science companies. (2)Excludes properties classified as held for sale, of which land parcels represent approximately 1% of total non-income producing assets. Total consolidated annual net operating income related to these dispositions, including our partners’ share, is $118 million (based on 3Q25 annualized results). (3)Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025. (5)Source: Alzheimer’s Association, “2025 Alzheimer’s Disease Facts and Figures.” Represents the latest published data, which reflects the U.S. estimate for 2025. (2)Source: AstraZeneca, “ AstraZeneca plans to invest $50 billion in America for medicines manufacturing and R&D,” July 21, 2025. (1)Represents our share of the sales price, net of seller credits and sales costs. (6)Represents 2.5% of gross assets as of December 31, 2025. Refer to “Gross assets” under “Definitions and reconciliations” in the Supplemental Information for additional details. (2)Refer to “Same property performance” in the Supplemental Information for additional details. funding. for our investors. As of December 31, 2025. Refer to “Definitions and reconciliations” in the Supplemental Information for additional details. | |
| Sources: S&P Global Market Intelligence, Bloomberg, or company filings (data not disclosed for SBAC, PSA, and WY) as of September 30, 2025, except for ARE, which is as of December 31, 2025. (6)Relates to the resignation of an executive officer, Daniel J. Ryan, from his position as Co-President & Regional Marketing Director - San Diego. December 31, 2025 would have decreased by 1.7%, and would have increased by 0.9%, respectively, compared to the corresponding periods in 2024. and tenant-funded and tenant-built landlord improvements. (6)Approximately 69% of the 519,851 RSF expiring leases are located on a Megacampus. | |
| (4)Top 15% ranking represents credit rating levels from S&P Global Ratings and Moody’s Ratings for publicly traded U.S. REITs, from Bloomberg Professional Services and Nareit, as of December 31, 2025. | |
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