Alnylam Pharmaceuticals, Inc. insider trading
In twelve months insiders at Alnylam Pharmaceuticals bought nothing and sold $44.0M on the open market; 136 of the 279 sales were under plans set months before.
New to this? How to read this page
- Insiders are the people who run the company: officers, directors and owners of 10% or more. They must report a trade on Form 4 within two business days.
- A purchase on the open market is the strongest sign: the insider spent their own money.
- A sale under a trading plan (Rule 10b5-1) says little: its dates were fixed months before. Sales outside a plan say more, but insiders sell for many reasons, such as taxes or a house.
- Grants, option exercises and shares held back for tax are left out.
- What is a Form 4? · Form 4 codes
What kind of trades
Insiders only sold: 279 sales worth $44.0M, and 136 of them were under plans set months before, which say little.
Every Form 4 line of the last twelve months, counted by kind. The grades come from the filing itself: whether the insider paid cash, whether a plan set the date, whether pay was taken in stock by choice.
Insider trades on the share price
last twelve months34 marks over twelve months, each in its grade: solid for the stronger signs, hollow or grey for the ones that say little.
The blue line is the daily close over twelve months. Each mark is one insider's trades on one day, on that day's price, sized by dollar value. Solid marks are the stronger signs; hollow and grey marks say little. Hover or tap a mark for who, how much and why.
Trades worth a closer look
A purchase stands out when two or more of these hold: a senior insider, several insiders buying within 90 days, a fall of 10% or more in the three months before, or over $1 million. A sale outside a plan is judged the same way. These are the Feed's rules.
Who traded
dollars, twelve months8 insiders traded. The most: Greenstreet Yvonne, sale outside a plan $8.8M; sale under a plan $11.6M.
One row per insider, sold to the left and bought to the right, split by grade: the paler part of a bar is the part that says little.
How it compares
every company on the siteOpen-market sales, twelve months
Open-market purchases, twelve months
The bar ranks every company on the site from the lowest on the left to the highest on the right, in three equal thirds; the small figures under it are the values where each third starts, and the black tick is the middle company. The orange dot is this company; the grey ticks are the other companies in its industry (hover or tap for names). A hatched block is companies tied at none.
Every Form 4 line
| Traded | Insider | Role | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|---|
| 2 October 2026 | Supran Bryan | EVP, CLO and Secretary | Saleafter a 30% fall over three months · 55% below its one-year high · Form 144 notice 2 October 2026 | 1,758 | $226.88 | $398,855 | Form 4 |
| 1 June 2026 | Pyott David E I | Director | Saletrading plan set in advance · Form 144 notice 1 June 2026 | 921 | $297.71 | $274,191 | Form 4 |
| 1 June 2026 | Pyott David E I | Director | Saletrading plan set in advance · Form 144 notice 1 June 2026 | 1,175 | $298.91 | $351,219 | Form 4 |
| 1 June 2026 | Pyott David E I | Director | Saletrading plan set in advance · Form 144 notice 1 June 2026 | 1,222 | $299.87 | $366,441 | Form 4 |
| 1 June 2026 | Pyott David E I | Director | Saletrading plan set in advance · Form 144 notice 1 June 2026 | 495 | $300.72 | $148,856 | Form 4 |
| 1 June 2026 | Pyott David E I | Director | Saletrading plan set in advance · Form 144 notice 1 June 2026 | 17 | $302.65 | $5,145 | Form 4 |
| 6 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance · Form 144 notice 6 April 2026 | 56 | $320.14 | $17,928 | Form 4 |
| 6 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance · Form 144 notice 6 April 2026 | 909 | $329.76 | $299,752 | Form 4 |
| 6 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance · Form 144 notice 6 April 2026 | 829 | $330.46 | $273,951 | Form 4 |
| 6 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance · Form 144 notice 6 April 2026 | 293 | $331.89 | $97,244 | Form 4 |
| 6 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance · Form 144 notice 6 April 2026 | 199 | $333.94 | $66,454 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 265 | $316.61 | $83,902 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 359 | $317.44 | $113,961 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 209 | $318.47 | $66,560 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 86 | $319.69 | $27,493 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 147 | $320.62 | $47,131 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 224 | $321.64 | $72,047 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 245 | $322.86 | $79,101 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 81 | $323.64 | $26,215 | Form 4 |
| 2 April 2026 | McLaughlin Melissa | Chief Human Resources Officer | Saletrading plan set in advance | 8 | $325.49 | $2,604 | Form 4 |
| 5 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 654 | $322.33 | $210,804 | Form 4 |
| 5 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 740 | $323.55 | $239,427 | Form 4 |
| 5 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 510 | $324.59 | $165,541 | Form 4 |
| 5 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 500 | $326.08 | $163,040 | Form 4 |
| 5 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 124 | $321.81 | $39,904 | Form 4 |
| 5 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 233 | $323.25 | $75,317 | Form 4 |
| 5 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 148 | $324.60 | $48,041 | Form 4 |
| 5 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 153 | $326.24 | $49,915 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 106 | $319.03 | $33,817 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 102 | $320.01 | $32,641 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 215 | $320.81 | $68,974 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 289 | $321.82 | $93,006 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 350 | $323.01 | $113,054 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 767 | $323.84 | $248,385 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 272 | $324.88 | $88,367 | Form 4 |
| 4 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 208 | $325.67 | $67,739 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 135 | $319.03 | $43,069 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 129 | $320.01 | $41,281 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 274 | $320.81 | $87,902 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 368 | $321.82 | $118,430 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 444 | $323.01 | $143,416 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 973 | $323.84 | $315,096 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 345 | $324.88 | $112,084 | Form 4 |
| 4 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 265 | $325.67 | $86,303 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 114 | $319.03 | $36,369 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 109 | $320.01 | $34,881 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 230 | $320.81 | $73,786 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 309 | $321.82 | $99,442 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 374 | $323.01 | $120,806 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 818 | $323.84 | $264,901 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 291 | $324.88 | $94,540 | Form 4 |
| 4 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 223 | $325.67 | $72,624 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 106 | $319.03 | $33,817 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 102 | $320.01 | $32,641 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 215 | $320.81 | $68,974 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 289 | $321.82 | $93,006 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 350 | $323.01 | $113,054 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 767 | $323.84 | $248,385 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 272 | $324.88 | $88,367 | Form 4 |
| 4 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 31% fall over three months · 33% below its one-year high | 208 | $325.67 | $67,739 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 29 | $319.03 | $9,252 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 28 | $320.01 | $8,960 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 59 | $320.81 | $18,928 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 79 | $321.82 | $25,424 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 96 | $323.01 | $31,009 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 210 | $323.84 | $68,006 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 75 | $324.88 | $24,366 | Form 4 |
| 4 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 5 March 2026 | 57 | $325.67 | $18,563 | Form 4 |
| 3 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 355 | $316.74 | $112,443 | Form 4 |
| 3 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 317 | $319.06 | $101,142 | Form 4 |
| 3 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 640 | $320.48 | $205,107 | Form 4 |
| 3 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 463 | $321.50 | $148,854 | Form 4 |
| 3 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 289 | $316.55 | $91,483 | Form 4 |
| 3 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 282 | $318.62 | $89,851 | Form 4 |
| 3 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 722 | $320.51 | $231,408 | Form 4 |
| 3 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 359 | $321.58 | $115,447 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 65 | $323.62 | $21,035 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 124 | $324.65 | $40,257 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 356 | $325.63 | $115,924 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 541 | $326.81 | $176,804 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 454 | $327.67 | $148,762 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 138 | $328.71 | $45,362 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 234 | $329.71 | $77,152 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 112 | $330.85 | $37,055 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 129 | $331.93 | $42,819 | Form 4 |
| 2 March 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 53 | $332.64 | $17,630 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 50 | $323.62 | $16,181 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 97 | $324.65 | $31,491 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 277 | $325.63 | $90,200 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 421 | $326.81 | $137,587 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 353 | $327.67 | $115,668 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 107 | $328.71 | $35,172 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 182 | $329.71 | $60,007 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 87 | $330.85 | $28,784 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 101 | $331.93 | $33,525 | Form 4 |
| 2 March 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 42 | $332.64 | $13,971 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 47 | $323.62 | $15,210 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 90 | $324.65 | $29,218 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 258 | $325.63 | $84,013 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 392 | $326.81 | $128,110 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 329 | $327.67 | $107,803 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 100 | $328.71 | $32,871 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 170 | $329.71 | $56,051 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 81 | $330.85 | $26,799 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 94 | $331.93 | $31,201 | Form 4 |
| 2 March 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 3 March 2026 | 37 | $332.64 | $12,308 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 47 | $323.62 | $15,210 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 90 | $324.65 | $29,218 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 258 | $325.63 | $84,013 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 392 | $326.81 | $128,110 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 329 | $327.67 | $107,803 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 100 | $328.71 | $32,871 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 170 | $329.71 | $56,051 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 81 | $330.85 | $26,799 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 94 | $331.93 | $31,201 | Form 4 |
| 2 March 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 37 | $332.64 | $12,308 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 200 | $323.62 | $64,724 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 382 | $324.65 | $124,016 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 1,098 | $325.63 | $357,542 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 1,669 | $326.81 | $545,446 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 1,399 | $327.67 | $458,410 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 424 | $328.71 | $139,373 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 722 | $329.71 | $238,051 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 346 | $330.85 | $114,474 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 399 | $331.93 | $132,440 | Form 4 |
| 2 March 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 28% fall over three months · 34% below its one-year high | 160 | $332.64 | $53,222 | Form 4 |
| 27 February 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 27 February 2026 | 127 | $328.92 | $41,773 | Form 4 |
| 27 February 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 27 February 2026 | 2,259 | $330.73 | $747,119 | Form 4 |
| 27 February 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 27 February 2026 | 1,159 | $331.49 | $384,197 | Form 4 |
| 27 February 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 27 February 2026 | 942 | $332.48 | $313,196 | Form 4 |
| 27 February 2026 | Garg Pushkal | EVP Chief R&D | Saletrading plan set in advance · Form 144 notice 27 February 2026 | 140 | $334.39 | $46,815 | Form 4 |
| 17 February 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 February 2026 | 2,041 | $331.96 | $677,532 | Form 4 |
| 13 February 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 30% fall over three months · 36% below its one-year high | 2,242 | $310.08 | $695,201 | Form 4 |
| 13 February 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 30% fall over three months · 36% below its one-year high | 6,958 | $310.08 | $2.2 million | Form 4 |
| 13 February 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 30% fall over three months · 36% below its one-year high | 1,959 | $310.08 | $607,448 | Form 4 |
| 13 February 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 1,959 | $310.08 | $607,448 | Form 4 |
| 13 February 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 30% fall over three months · 36% below its one-year high | 2,242 | $310.08 | $695,201 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 197 | $367.52 | $72,401 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 562 | $368.76 | $207,243 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 644 | $370.00 | $238,280 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 485 | $371.24 | $180,051 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 280 | $372.93 | $104,420 | Form 4 |
| 13 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 122 | $374.33 | $45,668 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 39 | $353.95 | $13,804 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 42 | $355.16 | $14,917 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 41 | $356.09 | $14,600 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 96 | $357.17 | $34,288 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 123 | $358.18 | $44,056 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 85 | $359.14 | $30,527 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 155 | $360.22 | $55,834 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 98 | $361.45 | $35,422 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 73 | $362.38 | $26,454 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 47 | $363.55 | $17,087 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 199 | $364.83 | $72,601 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 220 | $365.56 | $80,423 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 50 | $366.41 | $18,320 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 41 | $367.40 | $15,063 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 92 | $368.62 | $33,913 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 40 | $369.48 | $14,779 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 18 | $370.87 | $6,676 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 3 | $372.46 | $1,117 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 14 | $374.44 | $5,242 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 19 | $375.65 | $7,137 | Form 4 |
| 12 January 2026 | Garg Pushkal | EVP Chief R&D | Saleafter a 20% fall over three months · 24% below its one-year high | 15 | $377.82 | $5,667 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 247 | $353.95 | $87,426 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 269 | $355.16 | $95,538 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 263 | $356.09 | $93,652 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 607 | $357.17 | $216,802 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 778 | $358.18 | $278,664 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 537 | $359.14 | $192,858 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 980 | $360.22 | $353,016 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 624 | $361.45 | $225,545 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 464 | $362.38 | $168,144 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 301 | $363.55 | $109,429 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 1,259 | $364.83 | $459,321 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 1,395 | $365.56 | $509,956 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 316 | $366.41 | $115,786 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 261 | $367.40 | $95,891 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 584 | $368.62 | $215,274 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 253 | $369.48 | $93,478 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 118 | $370.87 | $43,763 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 21 | $372.46 | $7,822 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 88 | $374.44 | $32,951 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 118 | $375.65 | $44,327 | Form 4 |
| 12 January 2026 | Greenstreet Yvonne | Chief Executive Officer | Saleafter a 20% fall over three months · 24% below its one-year high · Form 144 notice 12 November 2025 | 94 | $377.82 | $35,515 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 72 | $353.95 | $25,484 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 78 | $355.16 | $27,702 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 76 | $356.09 | $27,063 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 176 | $357.17 | $62,862 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 226 | $358.18 | $80,949 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 156 | $359.14 | $56,026 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 284 | $360.22 | $102,302 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 181 | $361.45 | $65,422 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 135 | $362.38 | $48,921 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 87 | $363.55 | $31,629 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 365 | $364.83 | $133,163 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 405 | $365.56 | $148,052 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 92 | $366.41 | $33,710 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 76 | $367.40 | $27,922 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 170 | $368.62 | $62,665 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 73 | $369.48 | $26,972 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 36 | $370.87 | $13,351 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 6 | $372.46 | $2,235 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 25 | $374.44 | $9,361 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 34 | $375.65 | $12,772 | Form 4 |
| 12 January 2026 | Poulton Jeffrey V. | EVP, Chief Financial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 27 | $377.82 | $10,201 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 39 | $353.95 | $13,804 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 42 | $355.16 | $14,917 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 41 | $356.09 | $14,600 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 96 | $357.17 | $34,288 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 123 | $358.18 | $44,056 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 85 | $359.14 | $30,527 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 155 | $360.22 | $55,834 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 98 | $361.45 | $35,422 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 73 | $362.38 | $26,454 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 47 | $363.55 | $17,087 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 199 | $364.83 | $72,601 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 220 | $365.56 | $80,423 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 50 | $366.41 | $18,320 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 41 | $367.40 | $15,063 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 92 | $368.62 | $33,913 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 40 | $369.48 | $14,779 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 19 | $370.87 | $7,047 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 2 | $372.46 | $745 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 14 | $374.44 | $5,242 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 19 | $375.65 | $7,137 | Form 4 |
| 12 January 2026 | Tanguler Tolga | EVP, Chief Commercial Officer | Saleafter a 20% fall over three months · 24% below its one-year high | 15 | $377.82 | $5,667 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 39 | $353.95 | $13,804 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 42 | $355.16 | $14,917 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 41 | $356.09 | $14,600 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 96 | $357.17 | $34,288 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 123 | $358.18 | $44,056 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 85 | $359.14 | $30,527 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 155 | $360.22 | $55,834 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 98 | $361.45 | $35,422 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 73 | $362.38 | $26,454 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 47 | $363.55 | $17,087 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 199 | $364.83 | $72,601 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 220 | $365.56 | $80,423 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 50 | $366.41 | $18,320 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 41 | $367.40 | $15,063 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 92 | $368.62 | $33,913 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 40 | $369.48 | $14,779 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 19 | $370.87 | $7,047 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 2 | $372.46 | $745 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 14 | $374.44 | $5,242 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 19 | $375.65 | $7,137 | Form 4 |
| 12 January 2026 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 13 January 2026 | 15 | $377.82 | $5,667 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 8,168 | $449.00 | $3.7 million | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 96 | $450.09 | $43,209 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 129 | $451.51 | $58,245 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 368 | $455.24 | $167,528 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 364 | $456.25 | $166,075 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 262 | $457.39 | $119,836 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 794 | $458.41 | $363,978 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 622 | $459.89 | $286,052 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 707 | $460.84 | $325,814 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 323 | $461.96 | $149,213 | Form 4 |
| 17 November 2025 | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Saletrading plan set in advance · Form 144 notice 17 November 2025 | 295 | $463.08 | $136,609 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 654 | $447.73 | $292,815 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,013 | $448.76 | $454,594 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,477 | $450.02 | $664,680 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 2,218 | $450.69 | $999,630 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,702 | $451.94 | $769,202 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,599 | $452.85 | $724,107 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 881 | $453.99 | $399,965 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 195 | $454.69 | $88,665 | Form 4 |
| 13 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 261 | $456.03 | $119,024 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 711 | $448.07 | $318,578 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 2,132 | $449.15 | $957,588 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 453 | $450.17 | $203,927 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,255 | $451.16 | $566,206 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,210 | $452.43 | $547,440 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,069 | $453.52 | $484,813 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 1,960 | $454.84 | $891,486 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 3,406 | $455.56 | $1.6 million | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 2,420 | $456.64 | $1.1 million | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 604 | $457.71 | $276,457 | Form 4 |
| 12 November 2025 | Greenstreet Yvonne | Chief Executive Officer | Saletrading plan set in advance · Form 144 notice 12 November 2025 | 430 | $458.42 | $197,121 | Form 4 |