greeksoup/ stock research

Zoetis Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 12 February 2026: press release. Guidance figures: 13 new. The quarter’s numbers.

Key takeaways

  • Fourth-quarter revenue grew 3%: Fourth-quarter revenue was $2.4 billion, up 3% reported and 4% on an organic operational basis. Source
  • Full-year revenue grew 2% reported: Full-year revenue was $9.5 billion, up 2% reported and 6% on an organic operational basis. Source
  • International revenue rose 7% organically: International revenue was $1.1 billion, up 8% reported and 7% organic operational; the reported figure includes timing effects covered under fiscal alignment below. Source
  • Long-acting OA pain antibodies approved: Lenivia, an OA pain antibody for dogs dosed up to three months, was approved in Canada and the EU in Q4; Portela, for cats, was also approved in Canada and the EU. Source
  • OA pain antibody sales declined in U.S.: Sales of the OA pain antibodies Librela and Solensia declined in Q4, partly offset by growth in parasiticides, ProHeart, Simparica and dermatology products. Source
  • Cost of sales ratio improved to 28.1%: Full-year adjusted cost of sales was 28.1% of revenue against 29.3%; the fourth-quarter ratio was 29.7% against 30.5%. Source
  • Q4 International sales pulled forward: Operational changes accelerated sales into Q4, adding about 2.5% to 3.5% to reported International growth; the trend is not expected at fiscal year-end 2026. Source

“Zoetis delivered solid results in 2025, demonstrating the strength and resilience of our portfolio across species, geographies, and channels.”

Kristin Peck, Chief Executive Officer of Zoetis

Guidance

AreaPeriodFigureAgainst last quarter
Revenue SourceFull year 2026$9.825 billion to $10.025 billionNew
Organic operational revenue growth SourceFull year 20263% to 5%New
Reported net income SourceFull year 2026$2.825 billion to $2.875 billionNew
Adjusted net income SourceFull year 2026$2.975 billion to $3.025 billionNew
Organic operational growth in adjusted net income SourceFull year 20263% to 6%New
Reported diluted EPS SourceFull year 2026$6.65 to $6.75New
Adjusted diluted EPS SourceFull year 2026$7.00 to $7.10New
Adjusted cost of sales as percentage of revenue SourceFull year 2026Approximately 28.0%New
Adjusted SG&A expenses SourceFull year 2026$2,430 to $2,490 millionNew
Adjusted R&D expenses SourceFull year 2026$715 to $725 millionNew
Adjusted interest expense and other (income)/deductions-net SourceFull year 2026Approximately $200 millionNew
Effective tax rate on adjusted income SourceFull year 2026Approximately 20.5%New
Certain significant items and acquisition and divestiture-related costs SourceFull year 2026Approximately $65 millionNew

What changed from last quarter

  • New guidance: Full-year 2026 guidance issued for revenue, net income, EPS and selected cost lines. Source
  • New: Veterinary Pathology Group acquired in November 2025, a UK and Ireland diagnostic laboratory group. Source
  • New: Conditional licenses reported for H5N2 avian influenza vaccines, not in the prior release. Source
  • New: Expected Fiscal Year Alignment introduced: one-month reporting lag to end in 2026. Source
  • New: Timing of annual price increases in certain International Subsidiaries shifted to early 2026. Source

Fourth quarter and full year

  • Fourth-quarter revenue grew 3%: Fourth-quarter revenue was $2.4 billion, up 3% reported and 4% on an organic operational basis. Source
  • Full-year revenue grew 2% reported: Full-year revenue was $9.5 billion, up 2% reported and 6% on an organic operational basis. Source
  • Full-year adjusted EPS of $6.41: Full-year adjusted net income was $2.8 billion, up 6% reported and 7% organic operational; adjusted diluted EPS rose 8% reported. Source
  • Fourth-quarter adjusted income rose 4%: Fourth-quarter adjusted net income rose 4% on an organic operational basis; adjusted figures exclude a net $45 million of purchase accounting, deal and significant items. Source

Segments and regions

  • U.S. revenue flat on organic basis: U.S. revenue was $1.2 billion in the quarter, down 2% reported and flat organically; full-year U.S. revenue was flat reported and up 4% organically. Source
  • International revenue rose 7% organically: International revenue was $1.1 billion, up 8% reported and 7% organic operational; the reported figure includes timing effects covered under fiscal alignment below. Source
  • Full-year International organic growth 8%: Full-year International revenue was $4.3 billion, up 4% reported and 8% organic operational, with foreign exchange reducing reported growth by 1%. Source
  • International segment earnings rose: International segment earnings were $574 million in Q4, up 10% reported from $523 million; U.S. segment earnings were $830 million. Source

“Advancing our innovative pipeline is central to our strategy, and we achieved key milestones in 2025, including the first regulatory approvals for long-acting OA pain products Lenivia and Portela.”

Kristin Peck, Chief Executive Officer of Zoetis

Products, pipeline and approvals

  • Long-acting OA pain antibodies approved: Lenivia, an OA pain antibody for dogs dosed up to three months, was approved in Canada and the EU in Q4; Portela, for cats, was also approved in Canada and the EU. Source
  • OA pain antibody sales declined in U.S.: Sales of the OA pain antibodies Librela and Solensia declined in Q4, partly offset by growth in parasiticides, ProHeart, Simparica and dermatology products. Source
  • International companion animal sales grew: International companion animal sales rose 7% reported and 4% operationally, led by parasiticides including Simparica Trio, diagnostics, Apoquel and Cytopoint. Source
  • Conditional licenses for emerging diseases: Conditional licenses were received for H5N2 avian influenza vaccines in chickens and lactating dairy cattle, and a conditional approval for Dectomax-CA1 Injectable against New World screwworm. Source
  • About 185 innovations in 2025: The company reported approximately 185 geographic expansion, lifecycle and new product innovations during 2025, including franchise approvals for Simparica Trio, Apoquel and Cytopoint. Source

Costs, margins and transformation

  • Cost of sales ratio improved to 28.1%: Full-year adjusted cost of sales was 28.1% of revenue against 29.3%; the fourth-quarter ratio was 29.7% against 30.5%. Source
  • Segment gross margins by region: U.S. gross margin was 82.8% in Q4 against 81.8%; International gross margin was 67.4% against 67.7%. Source
  • Adjusted R&D rose 7% in Q4: Adjusted R&D expenses were $199 million in Q4, up 7% reported; adjusted SG&A expenses were $615 million, down 1% reported. Source
  • Transformation costs not expected to recur: Business process transformation costs were $29 million for full year 2025, tied to the multi-year ERP program, and are not expected to recur. Source

“Our disciplined execution positions us well as we move into 2026 and lay the groundwork for the next phase of our innovation cycle, supporting sustainable growth and long-term value creation.”

Kristin Peck, Chief Executive Officer of Zoetis

Fiscal alignment and order timing

  • One-month reporting lag ends in 2026: International subsidiaries are included through November 30 while the U.S. reports December 31; the company expects to eliminate the one-month lag in 2026. Source
  • Q4 International sales pulled forward: Operational changes accelerated sales into Q4, adding about 2.5% to 3.5% to reported International growth; the trend is not expected at fiscal year-end 2026. Source
  • December 2025 orders moved into 2026: Processing of certain customer orders from December 2025 was delayed into calendar 2026 as part of the operational changes. Source
  • Annual International price increases moved: A shift in the timing of annual price increases in certain International Subsidiaries was implemented in early 2026, so increases and preceding buying fall in one calendar year. Source
  • Prior periods restated on adoption: On adoption, the company will apply the new accounting principle retroactively to prior periods, allowing comparison of results to historical operations. Source

Guidance basis and reconciliation

  • Guidance uses January exchange rates: The 2026 guidance reflects foreign exchange rates as of January 20, 2026; further detail is in the financial tables and on the conference call. Source
  • Purchase accounting excluded from adjusted EPS: Reconciling reported to adjusted 2026 guidance adds about $0.14 for significant items and acquisition costs and $0.21 for purchase accounting to diluted EPS. Source
  • Organic growth not reconciled to GAAP: The company does not reconcile forward organic operational adjusted net income growth to reported GAAP, citing uncertainty in foreign exchange effects of unusual items. Source

Shares, interest and acquisitions

  • Diluted shares fell about 3% in Q4: Weighted-average diluted shares were 438.6 million in Q4 against 451.1 million, and 443.8 million for the full year against 454.8 million. Source
  • Q4 net income and EPS both rose: Reported net income rose 4% to $603 million in Q4, and reported diluted EPS rose 6% to $1.37. Source
  • Interest expense rose 12% in Q4: Interest expense was $57 million in Q4, up 12% from $51 million; full-year interest expense was $222 million against $225 million. Source
  • Veterinary diagnostics laboratory acquired: In November the company acquired Veterinary Pathology Group, a UK and Ireland diagnostic laboratory group, expanding its diagnostics portfolio. Source

Coming up, as management said on 12 February 2026

  • Lenivia and Portela launches this year: Launches of Lenivia and Portela in Canada and the EU are expected in 2026. Source

Figures management reported

FigureReported
R&D expenses, Q4 and full year 2025 Source$199 million Q4; $698 million full year
Companion animal revenue, full year 2025 Source$6,587 million, up 5%
Livestock revenue, full year 2025 Source$2,764 million, down 5%
Dogs and cats revenue, full year 2025 Source$6,283 million, up 5%
Approvals of Lenivia and Portela SourceCanada and EU
Pipeline candidates with blockbuster potential Source12

Risks management discussed

  • External: Management said it navigated a dynamic operating environment while growth continued during 2025. Source
  • Financial: Asset impairment charges of $27 million for full year 2025 related to a product transition and an aquaculture product portfolio. Source

Earlier plans management reported on

  • On track: Management says it remains on track to receive a significant approval in a major market each year for the next several years. Source
  • Not stated: The release reports Lenivia received approval in Canada and the EU in Q4, which the prior release had anticipated for the EU. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.