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10x Genomics, Inc.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 6 August 2026: press release. Guidance figures: 2 raised. The quarter’s numbers.

Key takeaways

  • Revenue fell as settlement income dropped: Revenue was $151.0 million against $172.9 million a year earlier. Excluding $1.6 million of settlement revenue this year and $27.3 million last year, revenue rose 3%, as the company reported. Source
  • Operating and net results turned to loss: Operating loss was $19.6 million against operating income of $30.1 million. Net loss was $17.9 million, or $0.14 per diluted share, against net income of $34.5 million, or $0.28 per diluted share. Source
  • Revenue guidance range raised: The full-year 2026 revenue range rose to $610 million to $630 million from $600 million to $625 million. Source
  • Growth guidance raised on like basis: Growth over full year 2025, excluding settlement-related license and royalty revenue, is now 2% to 5%, against 0% to 4% in the prior release. Source
  • Gross margin rose to 74%: Gross margin was 74% against 72%. Management attributed the increase mainly to lower manufacturing costs, including $2.6 million of tariff refunds, and lower inventory write-downs. Source
  • Operating expenses up on lower settlement gain: Operating expenses were $132.1 million, up 39% from $95.0 million. The settlement gain was $3.4 million against $40.7 million a year earlier. Source
  • Atera early orders described as strong: Management described the customer response to Atera as extraordinary, citing engagement across the research ecosystem and very strong early order flow. No order values were given. Source
  • Cash and securities rose to $552.0 million: Cash, cash equivalents and marketable securities were $552.0 million at June 30, 2026, up from $539.8 million at March 31, 2026. Cash and cash equivalents alone were $502.5 million. Source

“The story of the quarter was the extraordinary customer response to Atera. We are highly encouraged by the engagement across the research ecosystem and the very strong early order flow,”

Serge Saxonov, Co-founder and CEO of 10x Genomics

Guidance

AreaPeriodFigureAgainst last quarter
Total revenue SourceFull year 2026$610 million to $630 millionRaised from $600 million to $625 million
Revenue growth excluding settlement license and royalty revenue SourceFull year 2026 compared with full year 20252% to 5%Raised from 0% to 4%

What changed from last quarter

  • Guidance raised: The full-year 2026 revenue range was raised, with the low end up $10 million and the high end up $5 million. Source
  • Guidance raised: The growth range excluding patent settlement license and royalty revenue was raised to 2% to 5% from 0% to 4%. Source
  • New: The company acquired Proteintech Genomics, a division within Proteintech Group, adding protein detection to its single cell and spatial platforms. Source
  • New: Multi-year research collaborations were announced with Cleveland Clinic and Lausanne University Hospital on diagnostic applications for cancer care. Source

Second quarter results

  • Revenue fell as settlement income dropped: Revenue was $151.0 million against $172.9 million a year earlier. Excluding $1.6 million of settlement revenue this year and $27.3 million last year, revenue rose 3%, as the company reported. Source
  • Operating and net results turned to loss: Operating loss was $19.6 million against operating income of $30.1 million. Net loss was $17.9 million, or $0.14 per diluted share, against net income of $34.5 million, or $0.28 per diluted share. Source
  • Six-month revenue and loss: For the six months ended June 30, 2026, revenue was $301.9 million against $327.8 million. Net loss was $31.4 million, against net income of $0.2 million, and diluted loss per share was $0.24. Source

Full-year 2026 guidance raised

  • Revenue guidance range raised: The full-year 2026 revenue range rose to $610 million to $630 million from $600 million to $625 million. Source
  • Growth guidance raised on like basis: Growth over full year 2025, excluding settlement-related license and royalty revenue, is now 2% to 5%, against 0% to 4% in the prior release. Source
  • Settlement revenue excluded from growth basis: The growth range excludes non-recurring license and royalty revenue from patent litigation settlements. The prior release excluded only the 2025 amount from its range.

“Combined with the continued momentum across the rest of the business and our strong operating foundation, we are uniquely well-positioned for the opportunities ahead.”

Serge Saxonov, Co-founder and CEO of 10x Genomics

Products and revenue mix

  • Consumables revenue rose 7%: Total consumables revenue was $130.8 million against $122.2 million. Single Cell consumables were $88.5 million against $85.8 million, and Spatial consumables were $42.3 million against $36.4 million. Source
  • Spatial consumables grew fastest: Spatial consumables revenue rose about 16% to $42.3 million, while Single Cell consumables rose about 3%. Spatial covers the Visium and Xenium products. Source
  • Instrument revenue fell 47%: Instruments revenue was $7.7 million against $14.5 million. Single Cell instruments were $3.1 million against $5.7 million, and Spatial instruments were $4.6 million against $8.8 million. Source
  • Services revenue rose 26%: Services revenue was $10.7 million against $8.5 million. Products and services revenue, excluding license and royalty revenue, was $149.1 million against $145.2 million. Source
  • License and royalty revenue fell: License and royalty revenue was $1.9 million against $27.8 million. The prior-year figure included non-recurring patent litigation settlement income. Source

Regional revenue mix

  • Americas revenue fell, Europe rose: Americas revenue was $85.0 million against $106.2 million, with United States revenue of $82.1 million including license and royalty revenue. Europe, Middle East and Africa rose to $40.0 million from $34.7 million. Source
  • China revenue fell about 35%: China revenue was $15.0 million against $23.2 million. Asia-Pacific excluding China rose to $11.1 million from $8.8 million, about 25% higher. Source
  • Asia-Pacific decline driven by China: Total Asia-Pacific revenue was $26.0 million against $32.0 million. The China decline accounts for more than the whole regional drop, with Asia-Pacific excluding China growing. Source

Margins and operating costs

  • Gross margin rose to 74%: Gross margin was 74% against 72%. Management attributed the increase mainly to lower manufacturing costs, including $2.6 million of tariff refunds, and lower inventory write-downs. Source
  • Operating expenses up on lower settlement gain: Operating expenses were $132.1 million, up 39% from $95.0 million. The settlement gain was $3.4 million against $40.7 million a year earlier. Source
  • R&D down, SG&A up: Research and development was $56.8 million against $61.2 million. Selling, general and administrative expense was $78.7 million against $74.4 million. Source
  • Stock compensation declined: Stock-based compensation was $25.6 million against $27.2 million. Research and development carried $10.5 million of it, and selling, general and administrative $13.2 million. Source

Atera response and strategy

  • Atera early orders described as strong: Management described the customer response to Atera as extraordinary, citing engagement across the research ecosystem and very strong early order flow. No order values were given. Source
  • Proteintech Genomics acquired: The company acquired Proteintech Genomics to add protein detection to its single cell and spatial platforms, which the release describes as strengthening its multiomics strategy. Source
  • Diagnostics collaborations with two hospitals: Multi-year research collaborations were announced with Cleveland Clinic and Lausanne University Hospital on diagnostic applications in cancer care, furthering the diagnostics strategy. Source

Cash, balance sheet and shares

  • Cash and securities rose to $552.0 million: Cash, cash equivalents and marketable securities were $552.0 million at June 30, 2026, up from $539.8 million at March 31, 2026. Cash and cash equivalents alone were $502.5 million. Source
  • Other receivables fell sharply: Accounts receivable, net, was $47.5 million at June 30, against $47.0 million at December 31, 2025. Other receivables fell to $3.1 million from $35.5 million. Source
  • Equity rose, deficit widened: Total stockholders’ equity was $825.5 million, against $796.3 million at December 31, 2025. Accumulated deficit was $1,542.0 million, and total liabilities were $204.5 million. Source
  • Weighted share count increased: Weighted-average basic shares were 130.0 million, against 123.8 million a year earlier. Diluted shares were also 130.0 million, against 124.5 million. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.