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Teva Pharmaceutical Industries Ltd.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 28 January 2026: press release. Guidance figures: 11 new, 2 kept. The quarter’s numbers.

Key takeaways

  • 2025 revenue rose 4%: Revenue was $17,258 million for 2025, up 4% in U.S. dollars and 3% in local currency. Higher AUSTEDO, AJOVY and UZEDY sales and duvakitug milestone payments were partly offset by the Japan divestment. Source
  • Non-GAAP EPS $2.93 for 2025: Non-GAAP diluted EPS was $2.93 for 2025, against $2.49 in 2024. GAAP diluted EPS was $1.21, against a loss of $1.45. Non-GAAP operating margin was 28.4% of revenue. Source
  • 2025 results above prior expected ranges: The January 11, 2026 presentation gave 2025 ranges, including non-GAAP diluted EPS of $2.55 to $2.65 and free cash flow of $1.6 to $1.9 billion. Reported figures were $2.93 and $2,396 million.
  • US segment revenue up 34%: U.S. segment revenue was $2,643 million in the fourth quarter, up 34%, mainly from the duvakitug milestone payments and AUSTEDO. Segment profit rose to $1,181 million, a 44.7% margin, from $569 million. Source
  • Key innovative brands passed $3 billion: Key innovative brands, AUSTEDO, AJOVY and UZEDY, reached over $3 billion of 2025 revenue, up 35% in local currency. Source
  • Gross margin rose to 51.8%: GAAP gross margin was 51.8% for 2025, against 48.7%, and non-GAAP gross margin was 55.9%, against 53.3%. Management attributed the increase mainly to product mix, led by AUSTEDO, and to duvakitug milestone payments. Source
  • Free cash flow reached $2.4 billion: Free cash flow was $2,396 million in 2025, against $2,068 million in 2024. It included $1,214 million of beneficial interest collected on securitized receivables. Source

“Our key innovative brands led our growth, reaching $1 billion in revenues in the fourth quarter of 2025 for the first time”

Mr. Richard Francis, Teva's President and CEO

Guidance

AreaPeriodFigureAgainst last quarter
Revenues Source2026$16.4 - $16.8 billionNew
Non-GAAP operating income Source2026$4.55 - $4.8 billionNew
Adjusted EBITDA Source2026$5.0 - $5.3 billionNew
Non-GAAP diluted EPS Source2026$2.57 - $2.77New
Free cash flow Source2026$2.0 - $2.4 billionNew
AUSTEDO revenues Source2026$2,400 - $2,550 millionNew
AJOVY revenues Source2026$750 - $790 millionNew
UZEDY revenues Source2026$250 - $280 millionNew
Finance expenses Source2026~$800 millionNew
Tax rate Source202616% - 19%New
Capital expenditure Source2026$0.5 billionNew
Non-GAAP operating income margin Source202730%Kept
Transformation net savings Sourceby 2027~$700 millionKept

What changed from last quarter

  • New guidance: Numeric 2026 guidance was given for revenues, operating income, adjusted EBITDA, EPS and free cash flow. The January presentation had given only directional 2026 commentary. Source
  • Guidance kept: The 2027 operating profit target of 30% was given in the January presentation and is repeated in the release.
  • New: From January 1, 2026, Anda is no longer reported in the United States segment and is reported within Other Activities. Source
  • New: A Royalty Pharma funding agreement provides up to $500 million to fund development of anti-IL-15 for vitiligo, announced in January 2026. Source
  • New: Teva and Abingworth amended the development funding agreement, adding $50 million of development funding for DARI (ICS-SABA). Source

Full-year and fourth-quarter results

  • 2025 revenue rose 4%: Revenue was $17,258 million for 2025, up 4% in U.S. dollars and 3% in local currency. Higher AUSTEDO, AJOVY and UZEDY sales and duvakitug milestone payments were partly offset by the Japan divestment. Source
  • Fourth-quarter revenue up 11%: Fourth-quarter revenue was $4,711 million, up 11% in U.S. dollars and 9% in local currency. Management attributed the rise mainly to the duvakitug milestone payments and higher AUSTEDO revenue. Source
  • Operating income positive against prior loss: Operating income was $2,157 million in 2025, or 12.5% of revenues. The 2024 result included goodwill impairment charges, and 2025 benefited from lower other asset impairments. Source
  • Non-GAAP EPS $2.93 for 2025: Non-GAAP diluted EPS was $2.93 for 2025, against $2.49 in 2024. GAAP diluted EPS was $1.21, against a loss of $1.45. Non-GAAP operating margin was 28.4% of revenue. Source
  • 2025 results above prior expected ranges: The January 11, 2026 presentation gave 2025 ranges, including non-GAAP diluted EPS of $2.55 to $2.65 and free cash flow of $1.6 to $1.9 billion. Reported figures were $2.93 and $2,396 million.

Segments and regions

  • US segment revenue up 34%: U.S. segment revenue was $2,643 million in the fourth quarter, up 34%, mainly from the duvakitug milestone payments and AUSTEDO. Segment profit rose to $1,181 million, a 44.7% margin, from $569 million. Source
  • Full-year segment profit by region: For 2025, United States segment profit was $3,356 million, up from $2,296 million, and Europe segment profit was $1,303 million, down from $1,575 million. Source
  • Europe revenue down 10% in local currency: Europe segment revenue was $1,314 million in the fourth quarter, down 3% in U.S. dollars and 10% in local currency. Management cited lower product-rights sale proceeds, generic and OTC products and COPAXONE, partly offset by AJOVY. Source
  • International Markets down 20% on Japan exit: International Markets revenue was $528 million in the fourth quarter, down 20% in both dollars and local currency. The March 31, 2025 divestment of the Japan business venture and lower product-rights proceeds were the main causes. Source

“Throughout the year, our teams executed with discipline across the business, driving momentum in innovative medicines, scaling our global generics and biosimilars portfolio”

Mr. Richard Francis, Teva's President and CEO

Products and customers

  • Key innovative brands passed $3 billion: Key innovative brands, AUSTEDO, AJOVY and UZEDY, reached over $3 billion of 2025 revenue, up 35% in local currency. Source
  • AUSTEDO fourth-quarter U.S. growth: AUSTEDO U.S. revenue was $725 million in the fourth quarter, up 40%, mainly from volume growth and lower sales allowances. AUSTEDO International Markets revenue rose 29% to $9 million. Source
  • AJOVY and UZEDY grew on volume: AJOVY U.S. revenue was $105 million, up 68% mainly on volume. UZEDY U.S. revenue was $55 million, up 28%, also mainly on volume. Source
  • Biosimilar portfolio ranked second-largest: Management said the biosimilar portfolio is the second-largest in the industry and has launched the most biosimilars since 2020. Source

Costs, margins and pricing

  • Gross margin rose to 51.8%: GAAP gross margin was 51.8% for 2025, against 48.7%, and non-GAAP gross margin was 55.9%, against 53.3%. Management attributed the increase mainly to product mix, led by AUSTEDO, and to duvakitug milestone payments. Source
  • Fourth-quarter non-GAAP gross margin 60.3%: Fourth-quarter non-GAAP gross margin was 60.3%, up from 54.8%. The company cited the duvakitug milestone and product mix, partly offset by lower product-rights sale proceeds. Source
  • G&A rose on transformation costs: Selling and marketing expenses rose 6% to $2,686 million, to support AUSTEDO growth and due to exchange rate effects. General and administrative expenses rose 11%, mainly on Transformation program costs. Source
  • Europe margin fell on mix and hedging: Europe gross margin was 53.9% in the fourth quarter, against 58.6%, and Europe segment profit fell 30%. Management cited lower product-rights proceeds, hedging costs and product mix. Source

“Together, these pipeline assets represent a potential of over $10 billion”

Mr. Richard Francis, Teva's President and CEO

Cash, debt and capital

  • Free cash flow reached $2.4 billion: Free cash flow was $2,396 million in 2025, against $2,068 million in 2024. It included $1,214 million of beneficial interest collected on securitized receivables. Source
  • Operating cash flow lifted by milestones: Operating cash flow was $1,649 million in 2025, against $1,247 million. Management said duvakitug milestone payments drove the increase, partly offset by higher legal settlement payments. Source
  • Gross and net debt reduced: Debt fell after $1,812 million of senior notes were repaid at maturity. Average debt maturity was about 5.6 years at year end. Source
  • Credit ratings upgraded one level: Credit ratings were upgraded by one level at three rating agencies in 2025, which management linked to its improved capital structure and stronger underlying performance. Source
  • Capital investment of $501 million: Capital investment was $501 million in 2025, against $498 million in 2024, and $142 million in the fourth quarter. Source

Pipeline and strategy

  • Olanzapine LAI filed with FDA: The company submitted a New Drug Application for olanzapine LAI in December 2025, and is preparing for a U.S. launch subject to approval. Source
  • Fast track for two early assets: FDA fast track designations were received during 2025 for emrusolmin in multiple system atrophy and for anti-IL-15 in celiac disease. Source
  • Duvakitug Phase 3 started in two diseases: Phase 3 studies for duvakitug (anti-TL1A) were started in ulcerative colitis and Crohn's disease. Management said Teva is working with partner Sanofi on additional indications. Source

Transformation and manufacturing

  • Transformation savings of $70 million: Teva Transformation programs were announced on May 7, 2025. Savings reached $70 million in 2025, the first year reported. Source
  • Restructuring expense of $225 million: Restructuring expenses for 2025 related mainly to headcount reduction under the Transformation programs. The company excludes these expenses from non-GAAP results. Source
  • Europe plant impairment of $726 million: The fourth quarter included a $726 million impairment of long-lived assets tied to a manufacturing facility in Europe. The company excludes this from non-GAAP results. Source

Legal, tax and financing costs

  • Legal provisions adjusted out: Legal settlement and loss contingency adjustments were $473 million for 2025, mainly a $220 million update to the opioid settlement provision, plus carvedilol and antitrust items. Source
  • Tax benefit from U.S. allowance release: The 2025 income tax benefit was $180 million on pre-tax income of $1,223 million. The non-GAAP tax rate was 15.8% for 2025. Source
  • Net interest expense of $824 million: Financial expenses, net were $934 million in 2025, mainly net interest of $824 million, against $981 million in 2024. Source

Coming up, as management said on 28 January 2026

  • Olanzapine LAI U.S. launch: Management is preparing for the U.S. launch of olanzapine LAI, subject to regulatory approval, which it listed among 2026 milestones. Source
  • 2026 late-stage pipeline readouts: Management expects multiple late-stage pipeline readouts in 2026 across immunology and neurology, including data for duvakitug and the anti-IL-15 programs. Source
  • Four innovative submissions targeted: Management targets four innovative product submissions over the next five years. Source
  • Form 10-K to follow: The Form 10-K for 2025 will be filed with the SEC and posted on Teva's investor relations website. Source
  • Work with Sanofi on indications: Management said Teva is working with partner Sanofi on targeting additional indications, with no date given. Source

Figures management reported

FigureReported
AUSTEDO global revenue, 2025 Source$2.26 billion, up 34% in local currency
AJOVY global revenue, 2025 Source$673 million, up 30% in local currency
UZEDY revenue, 2025 Source$191 million, up 63% in local currency
U.S. generic products revenue, Q4 2025 Source$673 million, flat
Generics revenue change, 2025 (local currency) SourceU.S. +2%, Europe -2%, International Markets -2%
U.S. generic prescription share, Q4 2025 Source6.5% (7.4% in Q4 2024)
AJOVY exit prescription share, Q4 2025 Source33.3% of subcutaneous anti-CGRP class
R&D expenses, net, 2025 Source$1,013 million
Duvakitug Phase 3 milestone payments Source$500 million
AUSTEDO XR patent expiry Source11 Orange Book patents, 2031 to 2041
Biosimilar approvals and launches SourceSELARSDI and EPYSQLI launched; PONLIMSI and DEGEVMA EMA approvals
FDA indication expansion, UZEDY SourceAdults with Bipolar 1 Disorder

Risks management discussed

  • Regulatory: U.S. government prices for AUSTEDO and AUSTEDO XR, negotiated with CMS, take effect for eligible Medicare patients from January 1, 2027. Source
  • Financial: In the fourth quarter, exchange rate movements net of hedging added $99 million to revenue but reduced operating income by $18 million. Source
  • Demand: BENDEKA and TREANDA revenue fell 14% in the fourth quarter, mainly from competition from alternative therapies and generic bendamustine products. Source
  • Demand: Europe generic revenue fell 4% in local currency in the fourth quarter, mainly from lower volumes and price reductions from market dynamics. Source

Earlier plans management reported on

  • Met: Management said the company achieved the targeted initial enrollment for adult and pediatric populations of the DARI Phase 3 trial by the end of 2025. Source
  • On track: Management said progress on deleveraging is in line with its 2027 targets, with debt reduced through cash flow, repayment and refinancing. Source
  • Not stated: Management said it continued to execute on the four key pillars of its Pivot to Growth strategy, which it announced in May 2023. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.