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Penumbra Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 25 February 2026: press release. The quarter’s numbers.

Key takeaways

  • Fourth-quarter revenue grew 22.1%: Fourth quarter revenue was $385.4 million, up 22.1% from $315.5 million a year earlier, or 20.9% in constant currency. Source
  • Full-year revenue rose 17.5%: Full-year 2025 revenue was $1,403.7 million, up 17.5% from $1,194.6 million, or 16.9% in constant currency. Source
  • Operating income rose from $9.3 million: Full-year income from operations was $189.2 million, against $9.3 million in 2024, a year that included a $76.9 million impairment charge. Source
  • U.S. growth outpaced international for the year: U.S. revenue rose 20.6% in the fourth quarter and 21.0% for the year. International rose 27.7% in the quarter, or 21.9% in constant currency, and 6.6% for the year. Source
  • Embolization and access grew fastest: Embolization and access revenue reached $130.7 million in the fourth quarter, up 37.0%, with U.S. embolization and access up 42.7%. Full-year revenue was $455.7 million, up 20.2%. Source
  • Final revenue above January preliminary range: Fourth-quarter revenue of $385.4 million was above the $383.0 million to $384.8 million range in the January 15, 2026 preliminary release. Full-year revenue of $1,403.7 million was above the $1,401.3 million to $1,403.1 million range.
  • No full-year 2026 guidance: Management said it will not provide financial guidance for full year 2026. Source

“As such, with favorable product mix, improvement in productivity, and by leveraging our fixed costs on higher volume of new product sales during the year, our gross margin may be positively impacted in the future.”

Penumbra Inc., press release

What changed from last quarter

  • New: A proposed acquisition of Penumbra by Boston Scientific is named as the reason for the no-guidance and no-call decisions. The January 15, 2026 preliminary release does not mention it. Source

Results and growth drivers

  • Fourth-quarter revenue grew 22.1%: Fourth quarter revenue was $385.4 million, up 22.1% from $315.5 million a year earlier, or 20.9% in constant currency. Source
  • Full-year revenue rose 17.5%: Full-year 2025 revenue was $1,403.7 million, up 17.5% from $1,194.6 million, or 16.9% in constant currency. Source
  • Operating income rose from $9.3 million: Full-year income from operations was $189.2 million, against $9.3 million in 2024, a year that included a $76.9 million impairment charge. Source
  • Diluted EPS rose in both periods: Fourth-quarter GAAP diluted EPS was $1.20 against $0.86 a year earlier; full-year GAAP diluted EPS was $4.52 against $0.36. Source

Segments and regions

  • U.S. growth outpaced international for the year: U.S. revenue rose 20.6% in the fourth quarter and 21.0% for the year. International rose 27.7% in the quarter, or 21.9% in constant currency, and 6.6% for the year. Source
  • United States share of revenue: The United States represented 77.6% of fourth-quarter revenue and 77.8% for the full year; international was 22.4% and 22.2%. Source
  • International full-year growth was 6.6%: International revenue rose 6.6% for the full year, or 4.2% in constant currency, compared with 27.7% in the fourth quarter. Source

“Gross margin is impacted by product mix, regional mix, and production initiatives to support demand and create future efficiencies.”

Penumbra Inc., press release

Products and customers

  • Embolization and access grew fastest: Embolization and access revenue reached $130.7 million in the fourth quarter, up 37.0%, with U.S. embolization and access up 42.7%. Full-year revenue was $455.7 million, up 20.2%. Source
  • Thrombectomy growth in the quarter: Thrombectomy revenue was $254.7 million, up 15.7%, or 14.7% in constant currency. U.S. thrombectomy rose 12.4% in the quarter. Source
  • U.S. thrombectomy full-year growth: U.S. thrombectomy revenue for the full year was $771.5 million, up 19.3% from 2024. Source

Costs and margins

  • Fourth-quarter gross margin reached 68.0%: Gross profit was $262.1 million, or 68.0% of revenue, against 66.8% a year earlier. Gross margin is affected by product mix, regional mix and production initiatives. Source
  • 2024 gross margin carried impairment charge: Full-year gross margin was 67.1%, against 63.2% in 2024. The 2024 figure included a one-time $33.4 million inventory impairment charge. Source
  • Operating expenses fell as share of revenue: Full-year operating expenses were $753.2 million, or 53.7% of revenue, against 62.4% in 2024, which included the $76.9 million impairment charge. Source
  • SG&A rose with quarterly spend: Fourth-quarter SG&A was $181.1 million, against $147.9 million, and R&D was $21.8 million, against $20.0 million. Source

Final results against preliminary update

  • Final revenue above January preliminary range: Fourth-quarter revenue of $385.4 million was above the $383.0 million to $384.8 million range in the January 15, 2026 preliminary release. Full-year revenue of $1,403.7 million was above the $1,401.3 million to $1,403.1 million range.
  • Operating income within preliminary ranges: Fourth-quarter income from operations of $59.2 million was within the preliminary range of $56.9 million to $60.4 million.
  • Gross margin within preliminary range: Fourth-quarter gross margin of 68.0% was within the preliminary range of 67.9% to 68.1%. Full-year gross margin of 67.1% matched the preliminary figure.

Cash, balance sheet and EPS

  • Cash shifted into marketable investments: Cash and cash equivalents were $186.9 million at year end, down from $324.4 million. Marketable investments rose to $357.9 million from $15.7 million. Source
  • Property and equipment nearly doubled: Property and equipment, net was $117.4 million at year end, against $62.6 million a year earlier, per the balance sheet. Source
  • Non-GAAP EPS excludes tax benefits: Non-GAAP diluted EPS was $1.18 for the fourth quarter and $3.84 for the year, after excluding excess tax benefits on share-based compensation of $0.02 and $0.68 per share. Source

Guidance, reporting and deal context

  • No full-year 2026 guidance: Management said it will not provide financial guidance for full year 2026. Source
  • No conference call this quarter: The company will not host a conference call on the fourth quarter and full-year results. Source
  • Proposed Boston Scientific acquisition named: The release names Boston Scientific Corporation as the party to the proposed acquisition of Penumbra. Source

Coming up, as management said on 25 February 2026

  • Annual report filing expected: The company said it expects to file its Form 10-K for 2025 with the SEC on or before March 2, 2026. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.