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Neogenomics Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 17 February 2026: press release. Guidance figures: 11 new. The quarter’s numbers.

Key takeaways

  • Revenue rose 11% in Q4: Consolidated revenue was $190 million in the fourth quarter, up 11%, and $727 million for the year, up 10%. Source
  • Net loss narrowed in Q4, widened for year: Q4 net loss was $10 million, down 36%; full-year net loss was $108 million, up 37%, with diluted loss per share of $(0.84) for the year. Source
  • Clinical tests grew 10.7% in Q4: Clinical tests performed were 356,136 in Q4, up 10.7% including Pathline, and 1,399,703 for the year, up 12.1%. Excluding Pathline, growth was 6.5% in Q4 and 8.8% for the year. Source
  • NGS grew faster than the market: NGS grew 23% in Q4 and 22% for the year, which management described as well ahead of market growth. Source
  • MRD market sized above $20 billion: Management said RaDaR ST, its MRD assay, addresses a molecular residual disease monitoring market it sized at more than $20 billion. Source
  • GAAP gross margin 43.8% in Q4: GAAP gross profit margin was 43.8% in Q4 against 44.9% a year earlier, and 43.2% for the year against 43.9%. Source
  • Cash ended year at $160 million: Cash and cash equivalents were $160 million at quarter end, against $367 million a year earlier. Source

“I am pleased with our progress in 2025 and excited about our current momentum.”

Tony Zook, CEO of NeoGenomics

Guidance

AreaPeriodFigureAgainst last quarter
Consolidated revenue SourceFY 2026$793 million to $801 millionNew
Net loss (GAAP) SourceFY 2026$(63) million to $(50) millionNew
Adjusted EBITDA SourceFY 2026$55 million to $57 millionNew
Adjusted net income SourceFY 2026$21 million to $27 millionNew
Adjusted diluted EPS SourceFY 2026$0.16 to $0.21New
GAAP net loss per diluted share SourceFY 2026$(0.48) to $(0.38)New
Amortization of intangibles SourceFY 202630,000 and 30,000 (in thousands)New
Stock-based compensation SourceFY 202643,000 and 40,000 (in thousands, as listed)New
Other one-time expenses SourceFY 202611,000 and 7,000 (in thousands)New
Depreciation SourceFY 202639,000 and 36,000 (in thousands)New
Diluted shares SourceFY 2026130,000 thousandNew

What changed from last quarter

  • New guidance: Company issued full-year 2026 guidance for consolidated revenue, net loss and adjusted EBITDA; the January preliminary release contained no 2026 figures. Source
  • New: Company said it successfully resolved RaDaR ST patent litigation; the release gives no terms. Source

Fourth quarter and full-year results

  • Revenue rose 11% in Q4: Consolidated revenue was $190 million in the fourth quarter, up 11%, and $727 million for the year, up 10%. Source
  • Net loss narrowed in Q4, widened for year: Q4 net loss was $10 million, down 36%; full-year net loss was $108 million, up 37%, with diluted loss per share of $(0.84) for the year. Source
  • Adjusted EBITDA up in both periods: Adjusted EBITDA was $13 million in Q4, up 13%, and $43 million for the year, up 9%. Source
  • Volume, mix and reimbursement drove growth: Management attributed growth to more test volumes, a shift to higher-value tests and reimbursement initiatives; the Pathline acquisition also added revenue. Source

Clinical volumes and revenue per test

  • Clinical tests grew 10.7% in Q4: Clinical tests performed were 356,136 in Q4, up 10.7% including Pathline, and 1,399,703 for the year, up 12.1%. Excluding Pathline, growth was 6.5% in Q4 and 8.8% for the year. Source
  • Revenue per test rose to $488: Average revenue per clinical test rose 5% to $488 in Q4, or 7% excluding Pathline tests; the full-year figure was $471. Source
  • Clinical revenue rose 15% for the year: Full-year clinical revenue grew 15%, or 13% excluding the Pathline acquisition. Source

“We believe RaDaR ST, together with our PanTracer family of therapy selection solutions, will be a key driver of our revenue growth over the long term.”

Tony Zook, CEO of NeoGenomics

Products and community channel

  • NGS grew faster than the market: NGS grew 23% in Q4 and 22% for the year, which management described as well ahead of market growth. Source
  • Community channel cited as core base: Management said innovation reaches community oncology, where the company holds a leadership position and about 80% of cancer care is delivered. Source
  • MRD market sized above $20 billion: Management said RaDaR ST, its MRD assay, addresses a molecular residual disease monitoring market it sized at more than $20 billion. Source

Costs, margins and operating spend

  • GAAP gross margin 43.8% in Q4: GAAP gross profit margin was 43.8% in Q4 against 44.9% a year earlier, and 43.2% for the year against 43.9%. Source
  • Adjusted gross margin fell year on year: Adjusted gross profit margin was 46.4% in Q4, against 48.0%, and 46.0% for the year, against 47.1%. Source
  • Operating expenses held flat in Q4: Operating expenses were $97 million in the fourth quarter, flat with the prior-year quarter. Source
  • R&D and sales spend rose: Research and development was $9.2 million in Q4 against $8.0 million, and $37.1 million for the year against $31.2 million; sales and marketing was $92.0 million for the year against $84.7 million. Source

“We envision a world where every cancer treatment decision is as personal as the patient, and this drives what we do every day.”

Tony Zook, CEO of NeoGenomics

Cash, debt and cash flow

  • Cash ended year at $160 million: Cash and cash equivalents were $160 million at quarter end, against $367 million a year earlier. Source
  • Convertible debt of $201 million repaid: The company repaid $201.25 million of convertible debt in the year, and net financing outflows were $200.3 million. Source
  • Operating cash flow was $5.2 million: Net cash provided by operating activities was $5.2 million for the year, against $7.0 million in 2024. Source
  • Capital spending fell to $27 million: Purchases of property and equipment were $27.0 million for the year, against $41.1 million in 2024. Source

2026 guidance basis

  • GAAP and adjusted guidance differ by charges: The company said GAAP net loss for 2026 includes amortization of intangibles, stock-based compensation and other one-time expenses, which are removed from the adjusted figures. Source
  • Share count assumed at 130 million: Diluted shares for 2026 are assumed at 130,000 thousand at both ends of the range. Source
  • Guidance may change during the year: The company reserves the right to adjust its 2026 guidance at any time based on execution of its business plan. Source

Coming up, as management said on 17 February 2026

  • RaDaR ST MRD clinical launch imminent: Management described the clinical launch of the RaDaR ST MRD assay as imminent. Source
  • Modest MRD revenue expected in 2026: Management anticipates modest revenue contribution from MRD in 2026. Source

Figures management reported

FigureReported
Clinical tests performed, including Pathline SourceQ4 356,136 (up 10.7%); full year 1,399,703 (up 12.1%)
Average revenue per clinical test SourceQ4 $488 (up 4.9%); full year $471 (up 3.1%)
NGS growth SourceQ4 23%; full year 22%

Risks management discussed

  • Demand: Lower non-clinical revenue from pharmaceutical and biotech macro trends, plus a less favorable test mix, partly offset growth. Source
  • Operational: Higher compensation and benefit costs and higher supplies costs partly offset the revenue gain in gross profit. Source
  • Financial: Impairment charges for the year were $27.8 million, including an InVisionFirst-Lung intangible write-down and a loss on the Trapelo Health asset sale. Source
  • Regulatory: IP litigation costs for the year included legal fees and a settlement payment. Source
  • Operational: Acquisition and integration costs for the year covered consulting and legal fees, severance and employee retention, totalling $7.3 million. Source

Earlier plans management reported on

  • Met: Management said the restructuring program was completed in 2024, which reduced restructuring charges in the fourth quarter. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.