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Lucid Diagnostics Inc.: Q4 FY2025 earnings call

What management said about Q4 FY2025, from the documents filed with the SEC on 26 March 2026: press release. The quarter’s numbers.

Key takeaways

  • Processed 3,664 EsoGuard tests: The company processed 3,664 EsoGuard tests in 4Q25, up from 2,841 in 3Q25 per the prior release, and recognized $1.5 million of EsoGuard revenue. Source
  • GAAP net loss rose to $16.3M: GAAP net loss attributable to common stockholders was $16.3 million, or $(0.12) per share, against $11.5 million in 4Q24. Source
  • VA contract adds national access: The VA contract covers EsoGuard at Medicare-aligned pricing of $1,938 across about 170 VA medical centers under a single national framework. Source
  • Real-world data from 12,000 patients: Positive real-world data from nearly 12,000 at-risk patients showed a 95% technical success rate for EsoCheck and 95% of procedures completed in under two minutes. Source
  • Operating expenses rose to $15.5M: Operating expenses were $15.5 million in 4Q25, including $1.2 million of stock-based compensation, against $13.6 million in 4Q24. Source
  • Cash lower than in 3Q25: Cash and cash equivalents were $34.7 million at December 31, 2025, down from $47.3 million at September 30, 2025 and up from $22.4 million a year earlier. Source
  • Medicare coverage still expected near-term: Management said it still expects Medicare coverage for EsoGuard in the near-term, and listed it among the company's 2026 priorities. Source

“Throughout 2025, we established a strong commercial foundation for EsoGuard, demonstrating that we can consistently generate and sustain demand, drive physician adoption”

Lishan Aklog, M.D., Chairman and Chief Executive Officer

What changed from last quarter

  • New: The company was awarded a Department of Veterans Affairs contract for EsoGuard under the VA Federal Supply Schedule, with Medicare-aligned pricing of $1,938. Source

Results and growth drivers

  • Processed 3,664 EsoGuard tests: The company processed 3,664 EsoGuard tests in 4Q25, up from 2,841 in 3Q25 per the prior release, and recognized $1.5 million of EsoGuard revenue. Source
  • Revenue rose from a year earlier: Quarterly revenue was $1,504 thousand against $1,197 thousand in 4Q24; full-year 2025 revenue was $4,706 thousand against $4,346 thousand in 2024. Source
  • GAAP net loss rose to $16.3M: GAAP net loss attributable to common stockholders was $16.3 million, or $(0.12) per share, against $11.5 million in 4Q24. Source
  • Full-year non-GAAP loss of $44.0M: Full-year 2025 non-GAAP adjusted loss was $44.0 million, or $(0.43) per share, against $40.0 million in 2024. Source

Products and clinical data

  • VA contract adds national access: The VA contract covers EsoGuard at Medicare-aligned pricing of $1,938 across about 170 VA medical centers under a single national framework. Source
  • Real-world data from 12,000 patients: Positive real-world data from nearly 12,000 at-risk patients showed a 95% technical success rate for EsoCheck and 95% of procedures completed in under two minutes. Source
  • Physicians used EsoGuard appropriately: The company said physicians used EsoGuard appropriately in routine clinical practice in the real-world data set. Source

“As we move into 2026, our focus is on building on that foundation by converting demand into revenue”

Lishan Aklog, M.D., Chairman and Chief Executive Officer

Operating costs and non-GAAP items

  • Operating expenses rose to $15.5M: Operating expenses were $15.5 million in 4Q25, including $1.2 million of stock-based compensation, against $13.6 million in 4Q24. Source
  • Fair value change in other expense: Other expense was $2.3 million in 4Q25; the non-GAAP reconciliation adds back a $2,359 thousand change in fair value of convertible debt. Source
  • Non-GAAP loss excludes stock compensation: Non-GAAP adjusted loss was $12.6 million, or $(0.10) per share, against $10.3 million in 3Q25, after stock-based compensation and other non-cash items. Source

Capital, cash and share count

  • Cash lower than in 3Q25: Cash and cash equivalents were $34.7 million at December 31, 2025, down from $47.3 million at September 30, 2025 and up from $22.4 million a year earlier. Source
  • Annual report filed March 25: The audited 2025 results were filed on Form 10-K on March 25, 2026, the day before this release. Source
  • Weighted share count increased: Basic and diluted weighted shares were 131,070 thousand in 4Q25, against 108,176 thousand in 3Q25 and 58,378 thousand in 4Q24. Source

Strategy and 2026 priorities

  • Named priorities for 2026: Management listed 2026 priorities as deepening the VA relationship, expanding health system adoption, advancing commercial payor coverage, and securing Medicare coverage. Source
  • Build on 2025 foundation: The CEO said the company will build on the 2025 commercial foundation by converting demand into revenue. Source

Coverage and reimbursement path

  • Medicare coverage still expected near-term: Management said it still expects Medicare coverage for EsoGuard in the near-term, and listed it among the company's 2026 priorities. Source

Figures management reported

FigureReported
EsoGuard tests processed (4Q25) Source3,664
EsoGuard revenue (4Q25) Source$1.5 million
VA medical centers covered Sourceapproximately 170
Patients in real-world study Sourcenearly 12,000

Risks management discussed

  • Operational: Management said converting demand into revenue is the focus for 2026. Source
  • Demand: Adoption across health systems and commercial payor coverage are listed as priorities for 2026. Source

Earlier plans management reported on

  • Not stated: The prior release said Lucid was in the final stages of achieving Medicare coverage; this release says it still expects coverage in the near-term.

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.