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Lantheus Holdings, Inc.: Q2 FY2026 earnings call

What management said about Q2 FY2026, from the documents filed with the SEC on 6 August 2026: press release. The quarter’s numbers.

Key takeaways

  • Revenue rose 2.7% to $388.2M: Worldwide revenue was $388.2 million, up 2.7% from $378.0 million a year earlier. Six-month revenue rose 2.0% to $765.5 million. Source
  • Operating income up, adjusted down: Operating income rose 13.9% to $100.2 million. Adjusted operating income fell 6.9% to $142.0 million, and adjusted operating margin was 36.6% against 40.4%. Source
  • PYLARIFY sales declined 4.1%: PYLARIFY sales were $240.4 million, down from $250.6 million a year earlier. PYLARIFY is the largest product line in the quarter. Source
  • DEFINITY sales grew 5.2%: DEFINITY sales were $88.3 million, up from $83.9 million. Six-month DEFINITY sales rose 6.0% to $172.9 million. Source
  • Free cash flow reached $89.9M: Operating cash flow was $92.2 million and free cash flow was $89.9 million, against $79.1 million a year earlier. Capital expenditures were $2.3 million. Source
  • Cash rose to $593.3M: Cash and cash equivalents were $593.3 million at June 30, 2026, up from $359.1 million at December 31, 2025. The company has access to $750.0 million under a revolving credit line. Source
  • Curium to acquire Lantheus: Curium US Holdings LLC will acquire all outstanding shares for $102.50 per share in cash, plus non-transferable CVRs of up to $12.00 per share, for up to $114.50 per share. Source
  • Full-year guidance suspended: Lantheus suspended its full year 2026 guidance, which had been revenue of $1.4 billion to $1.45 billion and adjusted EPS of $5.00 to $5.25, in connection with the pending transaction. Source
  • LNTH-2501 received complete response letter: The FDA issued a Complete Response Letter for LNTH-2501 on June 26, 2026. Resolving facility inspection-related conditions identified in the letter is part of the path to approval. Source

“Together, Curium and Lantheus are positioned to create a radiopharmaceutical company spanning diagnostics and therapeutics, with the infrastructure and capabilities to serve patients in more than 70 countries”

Lantheus Holdings, Inc., press release

What changed from last quarter

  • Guidance withdrawn: Full-year 2026 revenue and adjusted fully diluted EPS guidance was suspended in connection with the pending Curium transaction. Source
  • New: Lantheus entered into a definitive merger agreement with Curium on August 3, 2026, announced after the first quarter release. Source
  • New: The FDA issued a Complete Response Letter for LNTH-2501 on June 26, 2026. The prior release had given a PDUFA date of June 29, 2026. Source
  • Ended: No conference call was planned for the second quarter 2026 results. The first quarter results had been discussed on a call. Source

Quarter results and earnings

  • Revenue rose 2.7% to $388.2M: Worldwide revenue was $388.2 million, up 2.7% from $378.0 million a year earlier. Six-month revenue rose 2.0% to $765.5 million. Source
  • Diluted EPS slightly lower: GAAP diluted EPS was $1.11 against $1.12. Adjusted diluted EPS was $1.55 against $1.57, down 1.3%. Diluted weighted shares were 67.5 million against 70.3 million. Source
  • Operating income up, adjusted down: Operating income rose 13.9% to $100.2 million. Adjusted operating income fell 6.9% to $142.0 million, and adjusted operating margin was 36.6% against 40.4%. Source

Product sales by franchise

  • PYLARIFY sales declined 4.1%: PYLARIFY sales were $240.4 million, down from $250.6 million a year earlier. PYLARIFY is the largest product line in the quarter. Source
  • DEFINITY sales grew 5.2%: DEFINITY sales were $88.3 million, up from $83.9 million. Six-month DEFINITY sales rose 6.0% to $172.9 million. Source
  • Neuraceq added $39.6M revenue: Neuraceq sales were $39.6 million. The prior-year quarter showed no Neuraceq revenue, and six-month Neuraceq sales were $75.1 million. Source
  • Strategic partnerships revenue rose: Strategic partnerships and other revenue was $19.9 million, up 71.9% from $11.6 million. SPECT revenue was nil, against $31.9 million, after the legacy SPECT business was divested. Source

“The Board of Directors of Lantheus has unanimously approved the transaction.”

Lantheus Holdings, Inc., press release

Operating expenses

  • Sales and marketing expense rose: Sales and marketing expense was $82.8 million against $41.0 million. Cost of goods sold was $146.3 million against $137.0 million. Source
  • G&A and R&D expense lower: General and administrative expense was $20.6 million against $66.5 million. Research and development expense was $38.2 million against $45.5 million. Source
  • Acquired intangible amortization doubled: Amortization of acquired intangible assets was $16.7 million against $8.0 million a year earlier. The company adds this amount back in its non-GAAP measures. Source

Margins and non-GAAP adjustments

  • Adjusted operating margin fell: Adjusted operating income was 36.6% of revenues, against 40.4% a year earlier. Six-month adjusted operating margin was 35.4% against 39.5%. Source
  • Contingent consideration adjustment excluded: A contingent consideration fair value adjustment of $31.4 million was removed in the non-GAAP reconciliation. No comparable item appeared in the prior-year quarter. Source
  • Large Other add-back in quarter: An item labelled Other was added back at $33.0 million in the quarter, against $1.2 million a year earlier. The release does not describe this item. Source

Cash flow and balance sheet

  • Free cash flow reached $89.9M: Operating cash flow was $92.2 million and free cash flow was $89.9 million, against $79.1 million a year earlier. Capital expenditures were $2.3 million. Source
  • Cash rose to $593.3M: Cash and cash equivalents were $593.3 million at June 30, 2026, up from $359.1 million at December 31, 2025. The company has access to $750.0 million under a revolving credit line. Source
  • Equity investments and notes changed: Investment in equity securities was $119.0 million, up from $42.2 million. Long-term notes receivable were $24.5 million, against $92.1 million at March 31, 2026. Source
  • Equity rose, debt steady: Total stockholders’ equity was $1,311.8 million, up from $1,089.8 million at year-end. Long-term debt and other borrowings net of current portion were $570.4 million. Source

Curium merger and guidance

  • Curium to acquire Lantheus: Curium US Holdings LLC will acquire all outstanding shares for $102.50 per share in cash, plus non-transferable CVRs of up to $12.00 per share, for up to $114.50 per share. Source
  • Transaction value and board approval: The company describes total transaction value as up to approximately $8.0 billion. The Lantheus Board of Directors unanimously approved the transaction. Source
  • Full-year guidance suspended: Lantheus suspended its full year 2026 guidance, which had been revenue of $1.4 billion to $1.45 billion and adjusted EPS of $5.00 to $5.25, in connection with the pending transaction. Source
  • No conference call this quarter: The company did not host a conference call for the second quarter 2026 results. The first quarter results had been discussed on a call. Source

Pipeline and regulatory updates

  • LNTH-2501 received complete response letter: The FDA issued a Complete Response Letter for LNTH-2501 on June 26, 2026. Resolving facility inspection-related conditions identified in the letter is part of the path to approval. Source
  • PNT2003 tentative approval under appeal: PNT2003 received FDA tentative approval earlier in 2026. A District Court ruling invalidating all patents asserted by ADACAP is on appeal before the Federal Circuit. Source
  • PYLARIFY TruVu approved in March: The FDA approved PYLARIFY TruVu, a new formulation of PYLARIFY, on March 6, 2026. The approval is referenced as part of the manufacturing and coverage work still under way. Source

Strategy and focus

  • Simplifying operations, radiodiagnostics focus: The company refers to a strategic program to simplify and streamline operations. It intends to focus mainly on radiodiagnostics and pursue value-maximizing alternatives for radiotherapeutic assets. Source
  • Launch readiness and pipeline plans: The company lists commercialization of marketed products, launch readiness for new products, and advancing a focused late-stage pipeline among its plans. Source

Coming up, as management said on 6 August 2026

  • Proxy statement and special meeting: The company intends to file preliminary and definitive proxy statements. The definitive proxy will be delivered to stockholders before a special meeting on the acquisition. Source
  • CVR milestones through 2030: Up to $12.00 per share in additional cash depends on specified commercial milestones for Lantheus products through 2030. Source

Figures management reported

FigureReported
PYLARIFY sales Source$240.4 million, down 4.1%
DEFINITY sales Source$88.3 million, up 5.2%
Neuraceq sales Source$39.6 million
Strategic partnerships and other revenue Source$19.9 million, up 71.9%
Research and development expense Source$38.2 million, against $45.5 million
LNTH-2501 regulatory status SourceComplete Response Letter issued June 26, 2026
PNT2003 regulatory status SourceFDA tentative approval; patents on appeal
SPECT revenue SourceNil, against $31.9 million

Earlier plans management reported on

  • Not stated: The company suspended its previously issued full-year 2026 guidance, rather than reaffirming it as in the first quarter release. Source
  • Not stated: The company refers to the Curium merger agreement as previously announced, dated August 3, 2026. Source

Other quarters

Summarised with AI from the documents the company filed with the SEC. Every point is checked against the filing before it is shown: management’s own words word for word, figures against the line or table row they come from. A point that fails the check is left out. Source opens the filing at that line.