TRV GP Vi, LLC
TRV GP Vi, LLC reported 4 US-listed holdings worth $232.3 million in its 13F for the quarter ended 30 June 2026, filed 10 August 2026. Its largest: Septerna Inc. (60.7%), Seaport Therapeutics Inc. (19.3%) and Rapport Therapeutics Inc. (17.4%). Against the quarter before, it opened 1 position, added to 0, trimmed 0 and sold out of 0.
The 4 largest of its 4 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.
What the fund reported holding at each quarter's end; hover a bar for the number of positions
What its reported holdings returned
Held through each quarter, the holdings it reported returned +47.4% over the 6 quarters to 30 June 2026, against +27.4% for the S&P 500.
Not the fund's own return: each 13F's holdings are kept unchanged until the next one, so trades inside a quarter, dividends, cash and fees are left out. A rough guide to how its picks have done over time.
What it did on the quarter
Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held
Opened 1
- Seaport Therapeutics Inc. SPTX$44.8 million
What it holds
| Company | Shares | Value | Of its book | Change in shares |
|---|---|---|---|---|
| Septerna Inc. SEPN | 4.2M | $141.0 million | 60.72% | no change |
| Seaport Therapeutics Inc. SPTX | 2.1M | $44.8 million | 19.27% | new |
| Rapport Therapeutics Inc. RAPP | 969.2K | $40.4 million | 17.39% | no change |
| Tango Therapeutics Inc. TNGX | 194.2K | $6.1 million | 2.61% | no change |