TRV GP V, LLC
TRV GP V, LLC reported 3 US-listed holdings worth $498.2 million in its 13F for the quarter ended 30 June 2026, filed 10 August 2026. Its largest: Rapport Therapeutics Inc. (52.5%), Septerna Inc. (41.8%) and Maze Therapeatics (5.7%). Against the quarter before, it opened 0 positions, added to 0, trimmed 1 and sold out of 0.
The 3 largest of its 3 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.
What the fund reported holding at each quarter's end; hover a bar for the number of positions
What its reported holdings returned
Held through each quarter, the holdings it reported returned +70.1% over the 6 quarters to 30 June 2026, against +27.4% for the S&P 500.
Not the fund's own return: each 13F's holdings are kept unchanged until the next one, so trades inside a quarter, dividends, cash and fees are left out. A rough guide to how its picks have done over time.
What it did on the quarter
Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held
Trimmed 1
- Rapport Therapeutics Inc. RAPP-854,708 shares · -12%
What it holds
| Company | Shares | Value | Of its book | Change in shares |
|---|---|---|---|---|
| Rapport Therapeutics Inc. RAPP | 6.3M | $261.7 million | 52.53% | -854.7K |
| Septerna Inc. SEPN | 6.2M | $208.2 million | 41.78% | no change |
| Maze Therapeatics MAZE | 950.8K | $28.4 million | 5.69% | no change |