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Samsara Biocapital, LLC

CIK 1744967 · latest 13F filed 14 August 2026 · Read the filing on EDGAR

Samsara Biocapital, LLC reported 24 US-listed holdings worth $1.22 billion in its 13F for the quarter ended 30 June 2026, filed 14 August 2026. Its largest: Scholar Rock Holding Corporation (31.2%), Alumis Inc. (14.7%) and Mineralys Therapeutics Inc. (13.0%). Against the quarter before, it opened 4 positions, added to 2, trimmed 5 and sold out of 2.

Filed before as Samsara BioCapital, LLC.

Reported holdings$1.22B+18.3% on Q1 2026
Positions24+2 on Q1 2026
The largest ten90.5%of its reported holdings
Latest 13FQ2 2026filed 14 August 2026
Where the money is
OpenedAdded toHeldTrimmed
SRRK31.2%ALMS14.7%MLYS13.0%SEPN8.7%ALMR5.5%NGNE4.4%KLRS4.3%SGP3.9%STRO2.9%IVA2.0%JBIO1.3%PBLS1.3%VTVT0.9%AQST0.9%10 more5.2%

The 14 largest of its 24 positions, each sized by its share of the reported holdings, coloured by the change in shares against Q1 2026.

Reported holdings, quarter by quarter
Q3 2024: $520.3 million in 42 positions$520MQ3 24Q4 2024: $728.6 million in 43 positions$729MQ4 24Q1 2025: $560.8 million in 37 positions$561MQ1 25Q2 2025: $488.9 million in 29 positions$489MQ2 25Q3 2025: $765.9 million in 27 positions$766MQ3 25Q4 2025: $969.3 million in 21 positions$969MQ4 25Q1 2026: $1.03 billion in 22 positions$1.03BQ1 26Q2 2026: $1.22 billion in 24 positions$1.22BQ2 26

What the fund reported holding at each quarter's end; hover a bar for the number of positions

What it did on the quarter

Opened 4Added 2Held 13Trimmed 5Sold out 2
Opened: 4Added: 2Held: 13Trimmed: 5Sold out: 2

Its positions against its 13F for the quarter to 31 March 2026; a change under 0.1% of a position counts as held

Opened 4

  1. Alamar Biosciences Inc. ALMR$67.2 million
  2. Parabilis Medicines Inc. Com PBLS$15.2 million
  3. Artiva Biotherapeutics Inc. ARTV$9.3 million
  4. Eloxx Pharmaceuticals Inc. ELOX$5.6 million

Added to 2

  1. Inventiva SA IVA+1.1 million shares · +22%
  2. Rani Therapeutics Holdings-A RANI+1.9 million shares · +22%

Trimmed 5

  1. Jade Biosciences Inc. JBIO-232,561 shares · -24%
  2. Upstream Bio Inc. UPB-382,330 shares · -52%
  3. X4 Pharmaceuticals Inc. XFOR-436,979 shares · -24%
  4. Kalaris Therapeutics Inc KLRS-66,906 shares · -1%
  5. Abivax SA ABVX-1,486 shares · -3%

Sold out of 2

  1. Arcellx Inc. ACLX$7.0 million last quarter
  2. Palvella Therapeutics Inc. Ne PVLA$4.8 million last quarter

What it holds

CompanySharesValueOf its bookChange in shares
Scholar Rock Holding Corporation SRRK6,897,652$379.4 million31.16%no change
Alumis Inc. ALMS6,345,219$178.6 million14.67%no change
Mineralys Therapeutics Inc. MLYS5,871,018$158.4 million13.01%no change
Septerna Inc. SEPN3,149,128$105.5 million8.66%no change
Alamar Biosciences Inc. ALMR2,480,310$67.2 million5.52%new
Neurogene Inc. NGNE1,717,127$54.0 million4.44%no change
Kalaris Therapeutics Inc KLRS12,881,175$52.4 million4.31%-66,906
Spyglass Pharma Inc. SGP2,109,953$47.0 million3.86%no change
Sutro Biopharma Inc. STRO1,062,872$35.3 million2.90%no change
Inventiva SA IVA6,314,805$23.9 million1.96%+1,120,000
Jade Biosciences Inc. JBIO736,237$16.4 million1.34%-232,561
Parabilis Medicines Inc. Com PBLS556,044$15.2 million1.25%new
VTV Therapeutics Inc. Class A New VTVT298,496$11.2 million0.92%no change
Aquestive Therapeutics Inc. AQST2,500,000$10.4 million0.85%no change
Nkarta Inc. NKTX3,507,666$9.9 million0.82%no change
Artiva Biotherapeutics Inc. ARTV954,861$9.3 million0.76%new
Rani Therapeutics Holdings-A RANI10,369,159$7.9 million0.65%+1,869,159
Agomab Therapeutics NV AGMB600,000$7.8 million0.64%no change
Abivax SA ABVX55,095$7.3 million0.60%-1,486
X4 Pharmaceuticals Inc. XFOR1,395,587$6.5 million0.54%-436,979
Eloxx Pharmaceuticals Inc. ELOX400,000$5.6 million0.46%new
Coherus Biosciences Inc. CHRS3,428,571$4.8 million0.39%no change
Upstream Bio Inc. UPB353,717$2.4 million0.20%-382,330
Gossamer Bio Inc. GOSS7,222,559$1.2 million0.10%no change
Every US-listed position in the fund's 13F for the quarter ended 30 June 2026, by the value it reported.
Read moreChange is shares against its 13F for the quarter before; the 2 it sold out of are in the box above.